JP2018536639A5 - - Google Patents
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- JP2018536639A5 JP2018536639A5 JP2018519914A JP2018519914A JP2018536639A5 JP 2018536639 A5 JP2018536639 A5 JP 2018536639A5 JP 2018519914 A JP2018519914 A JP 2018519914A JP 2018519914 A JP2018519914 A JP 2018519914A JP 2018536639 A5 JP2018536639 A5 JP 2018536639A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- alkoxy
- formula
- nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 54
- 229910052739 hydrogen Inorganic materials 0.000 claims description 32
- 239000001257 hydrogen Substances 0.000 claims description 32
- 229910052757 nitrogen Inorganic materials 0.000 claims description 32
- 150000002431 hydrogen Chemical class 0.000 claims description 24
- 150000001875 compounds Chemical class 0.000 claims description 22
- 229910052736 halogen Inorganic materials 0.000 claims description 22
- 150000002367 halogens Chemical class 0.000 claims description 22
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 18
- 229910052799 carbon Inorganic materials 0.000 claims description 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 8
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims description 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 4
- 150000002923 oximes Chemical class 0.000 claims description 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 42
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 35
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 18
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 18
- -1 nitro, hydroxyl Chemical group 0.000 claims 18
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 17
- 125000001072 heteroaryl group Chemical group 0.000 claims 14
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 13
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 12
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims 12
- 125000004670 alkyl amino thio carbonyl group Chemical group 0.000 claims 11
- 125000004767 (C1-C4) haloalkoxy group Chemical group 0.000 claims 10
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 claims 10
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 10
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 10
- 125000000623 heterocyclic group Chemical group 0.000 claims 10
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 claims 10
- 125000004769 (C1-C4) alkylsulfonyl group Chemical group 0.000 claims 9
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims 9
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 9
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 9
- 125000004768 (C1-C4) alkylsulfinyl group Chemical group 0.000 claims 8
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 8
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 claims 8
- 125000004399 C1-C4 alkenyl group Chemical group 0.000 claims 8
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 8
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 8
- 125000003282 alkyl amino group Chemical group 0.000 claims 8
- 125000004471 alkyl aminosulfonyl group Chemical group 0.000 claims 8
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 8
- 125000004122 cyclic group Chemical group 0.000 claims 8
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims 7
- 125000004414 alkyl thio group Chemical group 0.000 claims 7
- 125000000232 haloalkynyl group Chemical group 0.000 claims 7
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 claims 6
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims 6
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 claims 6
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 125000000262 haloalkenyl group Chemical group 0.000 claims 6
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 6
- 125000004760 (C1-C4) alkylsulfonylamino group Chemical group 0.000 claims 5
- 125000004771 (C1-C4) haloalkylsulfinyl group Chemical group 0.000 claims 5
- 125000006642 (C1-C6) cyanoalkyl group Chemical group 0.000 claims 5
- 125000006644 (C2-C6) haloalkynyl group Chemical group 0.000 claims 5
- 125000005103 alkyl silyl group Chemical group 0.000 claims 5
- 125000005159 cyanoalkoxy group Chemical group 0.000 claims 5
- 125000004966 cyanoalkyl group Chemical group 0.000 claims 5
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 5
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 claims 5
- 125000004995 haloalkylthio group Chemical group 0.000 claims 5
- 125000001424 substituent group Chemical group 0.000 claims 5
- ZMZDMBWJUHKJPS-UHFFFAOYSA-N thiocyanic acid Chemical compound SC#N ZMZDMBWJUHKJPS-UHFFFAOYSA-N 0.000 claims 5
- 125000004758 (C1-C4) alkoxyimino group Chemical group 0.000 claims 4
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims 4
- 125000004916 (C1-C6) alkylcarbonyl group Chemical group 0.000 claims 4
- 125000004845 (C1-C6) alkylsulfonylamino group Chemical group 0.000 claims 4
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 4
- 125000006771 (C1-C6) haloalkylthio group Chemical group 0.000 claims 4
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 claims 4
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 4
- 125000002619 bicyclic group Chemical group 0.000 claims 4
- 229910052801 chlorine Inorganic materials 0.000 claims 4
- 239000000460 chlorine Substances 0.000 claims 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 125000004844 (C1-C6) alkoxyimino group Chemical group 0.000 claims 3
- 125000004750 (C1-C6) alkylaminosulfonyl group Chemical group 0.000 claims 3
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 3
- 125000005947 C1-C6 alkylsulfonyloxy group Chemical group 0.000 claims 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 3
- 241000607479 Yersinia pestis Species 0.000 claims 3
- 239000003905 agrochemical Substances 0.000 claims 3
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 claims 3
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 claims 3
- 125000004682 aminothiocarbonyl group Chemical group NC(=S)* 0.000 claims 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 3
- 229910052794 bromium Inorganic materials 0.000 claims 3
- 229910052731 fluorine Inorganic materials 0.000 claims 3
- 239000011737 fluorine Substances 0.000 claims 3
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 claims 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 3
- 125000006340 pentafluoro ethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 claims 3
- 125000004665 trialkylsilyl group Chemical group 0.000 claims 3
- 125000003830 C1- C4 alkylcarbonylamino group Chemical group 0.000 claims 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 2
- 125000006620 amino-(C1-C6) alkyl group Chemical group 0.000 claims 2
- 125000006310 cycloalkyl amino group Chemical group 0.000 claims 2
- 125000006001 difluoroethyl group Chemical group 0.000 claims 2
- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 claims 2
- 125000003784 fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 claims 2
- 125000004216 fluoromethyl group Chemical group [H]C([H])(F)* 0.000 claims 2
- 238000009472 formulation Methods 0.000 claims 2
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 claims 2
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical group O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000006337 tetrafluoro ethyl group Chemical group 0.000 claims 2
- 125000004205 trifluoroethyl group Chemical group [H]C([H])(*)C(F)(F)F 0.000 claims 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims 2
- 125000006645 (C3-C4) cycloalkyl group Chemical group 0.000 claims 1
- 241001024304 Mino Species 0.000 claims 1
- 239000012868 active agrochemical ingredient Substances 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000005089 alkenylaminocarbonyl group Chemical group 0.000 claims 1
- 125000003302 alkenyloxy group Chemical group 0.000 claims 1
- 125000005153 alkyl sulfamoyl group Chemical group 0.000 claims 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 1
- 125000005332 alkyl sulfoxy group Chemical group 0.000 claims 1
- 125000004683 alkyl sulfoxy imino group Chemical group 0.000 claims 1
- 125000004691 alkyl thio carbonyl group Chemical group 0.000 claims 1
- 125000006615 aromatic heterocyclic group Chemical group 0.000 claims 1
- 125000005161 aryl oxy carbonyl group Chemical group 0.000 claims 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 1
- 239000004067 bulking agent Substances 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 125000005167 cycloalkylaminocarbonyl group Chemical group 0.000 claims 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 125000004993 haloalkoxycarbonyl group Chemical group 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 125000001475 halogen functional group Chemical group 0.000 claims 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
- 125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 claims 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- CMWTZPSULFXXJA-VIFPVBQESA-N naproxen Chemical group C1=C([C@H](C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-VIFPVBQESA-N 0.000 claims 1
- 239000000575 pesticide Substances 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 125000004434 sulfur atom Chemical group 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15191440 | 2015-10-26 | ||
| EP15191440.5 | 2015-10-26 | ||
| PCT/EP2016/075365 WO2017072039A1 (de) | 2015-10-26 | 2016-10-21 | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018536639A JP2018536639A (ja) | 2018-12-13 |
| JP2018536639A5 true JP2018536639A5 (enExample) | 2019-11-28 |
| JP6916175B2 JP6916175B2 (ja) | 2021-08-11 |
Family
ID=54360232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018519914A Active JP6916175B2 (ja) | 2015-10-26 | 2016-10-21 | 有害生物防除剤としての縮合二環式ヘテロ環誘導体 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10550116B2 (enExample) |
| EP (1) | EP3368521B1 (enExample) |
| JP (1) | JP6916175B2 (enExample) |
| KR (1) | KR102666624B1 (enExample) |
| CN (1) | CN108430986B (enExample) |
| AR (1) | AR106473A1 (enExample) |
| AU (1) | AU2016347345B2 (enExample) |
| BR (1) | BR112018008440B1 (enExample) |
| CA (1) | CA3002888A1 (enExample) |
| CL (1) | CL2018001077A1 (enExample) |
| CO (1) | CO2018004344A2 (enExample) |
| ES (1) | ES2894301T3 (enExample) |
| IL (1) | IL258623B (enExample) |
| MX (1) | MX392191B (enExample) |
| PE (1) | PE20181198A1 (enExample) |
| PH (1) | PH12018500877B1 (enExample) |
| RU (1) | RU2018119344A (enExample) |
| TW (1) | TWI720040B (enExample) |
| UY (1) | UY36966A (enExample) |
| WO (1) | WO2017072039A1 (enExample) |
| ZA (1) | ZA201803475B (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108349970B (zh) | 2015-11-05 | 2021-03-05 | 住友化学株式会社 | 稠合杂环化合物 |
| EA036621B1 (ru) | 2016-03-10 | 2020-12-01 | Ниссан Кемикал Корпорейшн | Конденсированные гетероциклические соединения и пестициды |
| MX2019000793A (es) | 2016-07-19 | 2019-06-20 | Bayer Cropscience Ag | Derivados de heterociclos biciclicos condensados como pesticidas. |
| EP3497102B1 (de) | 2016-08-15 | 2022-12-07 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| KR20190084310A (ko) | 2016-11-23 | 2019-07-16 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 살충제로서의 2-[3-(알킬술포닐)-2H-인다졸-2-일]-3H-이미다조[4,5-b]피리딘 유도체 및 유사한 화합물 |
| WO2018138050A1 (de) | 2017-01-26 | 2018-08-02 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| WO2019068572A1 (de) | 2017-10-04 | 2019-04-11 | Bayer Aktiengesellschaft | Heterocyclen-derivate als schädlingsbekämpfungsmittel |
| EP3305786A3 (de) * | 2018-01-22 | 2018-07-25 | Bayer CropScience Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
| CN111741958A (zh) * | 2018-02-21 | 2020-10-02 | 拜耳公司 | 作为害虫防治剂的稠合双环杂环衍生物 |
| CN111989328B (zh) * | 2018-04-20 | 2023-04-18 | 拜耳公司 | 作为害虫防治剂的杂环衍生物 |
| US11882835B2 (en) | 2018-07-10 | 2024-01-30 | Nihon Nohyaku Co., Ltd. | Benzimidazole compound having an optionally halogenated alkylenedioxy group or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide |
| JP2022500412A (ja) * | 2018-09-13 | 2022-01-04 | バイエル・アクチエンゲゼルシヤフト | 害虫防除剤としての複素環誘導体 |
| CN113710669A (zh) * | 2019-02-26 | 2021-11-26 | 拜耳公司 | 作为农药的稠合双环杂环衍生物 |
| JP7535532B2 (ja) | 2019-02-26 | 2024-08-16 | バイエル・アクチエンゲゼルシヤフト | 有害生物防除剤としての縮合二環式複素環式誘導体 |
| CN112824402B (zh) * | 2019-11-21 | 2023-02-28 | 浙江省化工研究院有限公司 | 一类苯并咪唑类衍生物、其制备方法及应用 |
| WO2021257863A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Pyrrolotriazine compounds as jak2 v617f inhibitors |
| US11691971B2 (en) | 2020-06-19 | 2023-07-04 | Incyte Corporation | Naphthyridinone compounds as JAK2 V617F inhibitors |
| US10994999B1 (en) | 2020-06-30 | 2021-05-04 | Donald Richard Wilshe | Agricultural composition for facilitating treatment of a plant |
| WO2022006456A1 (en) | 2020-07-02 | 2022-01-06 | Incyte Corporation | Tricyclic pyridone compounds as jak2 v617f inhibitors |
| BR112023000047A2 (pt) | 2020-07-02 | 2023-03-14 | Incyte Corp | Compostos de ureia tricíclicos como inibidores da v617f da jak2 |
| US11661422B2 (en) | 2020-08-27 | 2023-05-30 | Incyte Corporation | Tricyclic urea compounds as JAK2 V617F inhibitors |
| WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
| AR125273A1 (es) | 2021-02-25 | 2023-07-05 | Incyte Corp | Lactamas espirocíclicas como inhibidores de jak2 v617f |
| JP7644217B2 (ja) * | 2021-03-01 | 2025-03-11 | 日本農薬株式会社 | スルホンアミド基を有する縮合複素環化合物又はその塩類及び該化合物若しくはその塩類を含有する農園芸用殺虫剤又は動物用の外部若しくは内部寄生虫防除剤並びにそれらの使用方法 |
| AR126700A1 (es) * | 2021-08-10 | 2023-11-01 | Syngenta Crop Protection Ag | Derivados heterocíclicos activos como plaguicidas con sustituyentes que contienen azufre |
| JP2024177597A (ja) * | 2021-11-04 | 2024-12-20 | 日産化学株式会社 | インドール化合物の製造方法 |
| UY40138A (es) * | 2022-02-07 | 2023-08-31 | Syngenta Crop Protection Ag | Derivados de pirazolo[3,4-c]piridin-5-il]-2-quinoxalina o 2-quinolina activos como pesticidas con su |
| KR20240163688A (ko) | 2022-03-17 | 2024-11-19 | 인사이트 코포레이션 | Jak2 v617f 억제제로서의 삼환계 우레아 화합물 |
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| EP4603485A1 (en) * | 2022-10-14 | 2025-08-20 | Sumitomo Chemical Company, Limited | Sulfonamide composition and harmful-arthropod control composition containing same |
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