JP2018524113A5 - - Google Patents
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- JP2018524113A5 JP2018524113A5 JP2018501208A JP2018501208A JP2018524113A5 JP 2018524113 A5 JP2018524113 A5 JP 2018524113A5 JP 2018501208 A JP2018501208 A JP 2018501208A JP 2018501208 A JP2018501208 A JP 2018501208A JP 2018524113 A5 JP2018524113 A5 JP 2018524113A5
- Authority
- JP
- Japan
- Prior art keywords
- stimulator
- stimulation
- sensor
- treatment
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000638 stimulation Effects 0.000 claims 27
- 230000029058 respiratory gaseous exchange Effects 0.000 claims 13
- 230000000241 respiratory effect Effects 0.000 claims 8
- 201000004193 respiratory failure Diseases 0.000 claims 6
- 208000004756 Respiratory Insufficiency Diseases 0.000 claims 5
- 208000034972 Sudden Infant Death Diseases 0.000 claims 5
- 206010042440 Sudden infant death syndrome Diseases 0.000 claims 5
- 230000033001 locomotion Effects 0.000 claims 5
- 210000000278 spinal cord Anatomy 0.000 claims 5
- 239000000556 agonist Substances 0.000 claims 4
- 210000000779 thoracic wall Anatomy 0.000 claims 4
- 210000000038 chest Anatomy 0.000 claims 3
- 230000007794 irritation Effects 0.000 claims 3
- 230000001730 monoaminergic effect Effects 0.000 claims 3
- 229920006395 saturated elastomer Polymers 0.000 claims 3
- QJPPEMXOOWNICQ-UHFFFAOYSA-N 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1h-inden-2-yl)piperazine Chemical compound O1CCOC2=C1C=CC=C2N(CC1)CCN1C1CC2=CC=CC=C2C1 QJPPEMXOOWNICQ-UHFFFAOYSA-N 0.000 claims 2
- ASXGJMSKWNBENU-UHFFFAOYSA-N 8-OH-DPAT Chemical group C1=CC(O)=C2CC(N(CCC)CCC)CCC2=C1 ASXGJMSKWNBENU-UHFFFAOYSA-N 0.000 claims 2
- GHWJEDJMOVUXEC-UHFFFAOYSA-N 9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol Chemical compound C1NCCC=2C(Cl)=C(O)C(O)=CC=2C1C1=CC=CC=C1 GHWJEDJMOVUXEC-UHFFFAOYSA-N 0.000 claims 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- QWCRAEMEVRGPNT-UHFFFAOYSA-N buspirone Chemical compound C1C(=O)N(CCCCN2CCN(CC2)C=2N=CC=CN=2)C(=O)CC21CCCC2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 0.000 claims 2
- 229960002495 buspirone Drugs 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000005389 magnetism Effects 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- FELGMEQIXOGIFQ-CYBMUJFWSA-N (3r)-9-methyl-3-[(2-methylimidazol-1-yl)methyl]-2,3-dihydro-1h-carbazol-4-one Chemical compound CC1=NC=CN1C[C@@H]1C(=O)C(C=2C(=CC=CC=2)N2C)=C2CC1 FELGMEQIXOGIFQ-CYBMUJFWSA-N 0.000 claims 1
- GOTMKOSCLKVOGG-OAHLLOKOSA-N (5R)-8-chloro-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol Chemical compound C1([C@@H]2C3=CC(O)=C(Cl)C=C3CCN(C2)C)=CC=CC=C1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 0.000 claims 1
- WPVVMKYQOMJPIN-UHFFFAOYSA-N 1-(6-chloro-2-pyridinyl)-4-piperidinamine Chemical compound C1CC(N)CCN1C1=CC=CC(Cl)=N1 WPVVMKYQOMJPIN-UHFFFAOYSA-N 0.000 claims 1
- 239000003477 4 aminobutyric acid receptor stimulating agent Substances 0.000 claims 1
- -1 4-amino- (6 -Chloro-2-pyridyl) Chemical group 0.000 claims 1
- AADCDMQTJNYOSS-LBPRGKRZSA-N 5-chloro-3-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide Chemical compound CCN1CCC[C@H]1CNC(=O)C1=C(O)C(CC)=CC(Cl)=C1OC AADCDMQTJNYOSS-LBPRGKRZSA-N 0.000 claims 1
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- GJSURZIOUXUGAL-UHFFFAOYSA-N Clonidine Chemical compound ClC1=CC=CC(Cl)=C1NC1=NCCN1 GJSURZIOUXUGAL-UHFFFAOYSA-N 0.000 claims 1
- 229940127427 Glycine Agonists Drugs 0.000 claims 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 1
- WJAJPNHVVFWKKL-UHFFFAOYSA-N Methoxamine Chemical compound COC1=CC=C(OC)C(C(O)C(C)N)=C1 WJAJPNHVVFWKKL-UHFFFAOYSA-N 0.000 claims 1
- SBPRIAGPYFYCRT-UHFFFAOYSA-N N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide Chemical compound COC1=CC=CC=C1N1CCN(CCN(C(=O)C2CCCCC2)C=2N=CC=CC=2)CC1 SBPRIAGPYFYCRT-UHFFFAOYSA-N 0.000 claims 1
- 206010040880 Skin irritation Diseases 0.000 claims 1
- BLGXFZZNTVWLAY-CCZXDCJGSA-N Yohimbine Natural products C1=CC=C2C(CCN3C[C@@H]4CC[C@@H](O)[C@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-CCZXDCJGSA-N 0.000 claims 1
- 230000001154 acute effect Effects 0.000 claims 1
- 206010001053 acute respiratory failure Diseases 0.000 claims 1
- BLGXFZZNTVWLAY-UHFFFAOYSA-N beta-Yohimbin Natural products C1=CC=C2C(CCN3CC4CCC(O)C(C4CC33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-UHFFFAOYSA-N 0.000 claims 1
- 208000029028 brain injury Diseases 0.000 claims 1
- 229960002896 clonidine Drugs 0.000 claims 1
- 229940052760 dopamine agonists Drugs 0.000 claims 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 210000000624 ear auricle Anatomy 0.000 claims 1
- 229950007535 eticlopride Drugs 0.000 claims 1
- 210000002683 foot Anatomy 0.000 claims 1
- 210000001061 forehead Anatomy 0.000 claims 1
- 230000000977 initiatory effect Effects 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- FPCCSQOGAWCVBH-UHFFFAOYSA-N ketanserin Chemical compound C1=CC(F)=CC=C1C(=O)C1CCN(CCN2C(C3=CC=CC=C3NC2=O)=O)CC1 FPCCSQOGAWCVBH-UHFFFAOYSA-N 0.000 claims 1
- 229960005417 ketanserin Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229960005192 methoxamine Drugs 0.000 claims 1
- 230000004770 neurodegeneration Effects 0.000 claims 1
- 208000015122 neurodegenerative disease Diseases 0.000 claims 1
- 230000002474 noradrenergic effect Effects 0.000 claims 1
- 229960005343 ondansetron Drugs 0.000 claims 1
- IENZQIKPVFGBNW-UHFFFAOYSA-N prazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1=CC=CO1 IENZQIKPVFGBNW-UHFFFAOYSA-N 0.000 claims 1
- 229960001289 prazosin Drugs 0.000 claims 1
- FTSUPYGMFAPCFZ-ZWNOBZJWSA-N quinpirole Chemical compound C([C@H]1CCCN([C@@H]1C1)CCC)C2=C1C=NN2 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 0.000 claims 1
- 229950001037 quinpirole Drugs 0.000 claims 1
- XRXDAJYKGWNHTQ-UHFFFAOYSA-N quipazine Chemical compound C1CNCCN1C1=CC=C(C=CC=C2)C2=N1 XRXDAJYKGWNHTQ-UHFFFAOYSA-N 0.000 claims 1
- 229950002315 quipazine Drugs 0.000 claims 1
- 230000000284 resting effect Effects 0.000 claims 1
- 239000000952 serotonin receptor agonist Substances 0.000 claims 1
- 230000036556 skin irritation Effects 0.000 claims 1
- 231100000475 skin irritation Toxicity 0.000 claims 1
- 208000020431 spinal cord injury Diseases 0.000 claims 1
- 230000008961 swelling Effects 0.000 claims 1
- BLGXFZZNTVWLAY-SCYLSFHTSA-N yohimbine Chemical compound C1=CC=C2C(CCN3C[C@@H]4CC[C@H](O)[C@@H]([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 0.000 claims 1
- 229960000317 yohimbine Drugs 0.000 claims 1
- AADVZSXPNRLYLV-UHFFFAOYSA-N yohimbine carboxylic acid Natural products C1=CC=C2C(CCN3CC4CCC(C(C4CC33)C(O)=O)O)=C3NC2=C1 AADVZSXPNRLYLV-UHFFFAOYSA-N 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021188658A JP7520800B2 (ja) | 2015-07-13 | 2021-11-19 | 呼吸機能を可能にするために脊髄ネットワークにアクセスすること |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562191892P | 2015-07-13 | 2015-07-13 | |
| US62/191,892 | 2015-07-13 | ||
| PCT/US2016/041802 WO2017011410A1 (en) | 2015-07-13 | 2016-07-11 | Accessing spinal network to enable respiratory function |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021188658A Division JP7520800B2 (ja) | 2015-07-13 | 2021-11-19 | 呼吸機能を可能にするために脊髄ネットワークにアクセスすること |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018524113A JP2018524113A (ja) | 2018-08-30 |
| JP2018524113A5 true JP2018524113A5 (enExample) | 2019-09-05 |
| JP6983148B2 JP6983148B2 (ja) | 2021-12-17 |
Family
ID=57757566
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018501208A Active JP6983148B2 (ja) | 2015-07-13 | 2016-07-11 | 呼吸機能を可能にするために脊髄ネットワークにアクセスすること |
| JP2021188658A Active JP7520800B2 (ja) | 2015-07-13 | 2021-11-19 | 呼吸機能を可能にするために脊髄ネットワークにアクセスすること |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021188658A Active JP7520800B2 (ja) | 2015-07-13 | 2021-11-19 | 呼吸機能を可能にするために脊髄ネットワークにアクセスすること |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20180185642A1 (enExample) |
| EP (2) | EP3322477B1 (enExample) |
| JP (2) | JP6983148B2 (enExample) |
| CA (1) | CA3030615A1 (enExample) |
| HK (1) | HK1255688A1 (enExample) |
| WO (1) | WO2017011410A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2823592C (en) | 2011-01-03 | 2021-11-23 | The Regents Of The University Of California | High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury |
| ES2728143T3 (es) | 2011-11-11 | 2019-10-22 | Univ California | Estimulación transcutánea de la médula espinal: herramienta no invasiva para la activación del circuito locomotor |
| US9393409B2 (en) | 2011-11-11 | 2016-07-19 | Neuroenabling Technologies, Inc. | Non invasive neuromodulation device for enabling recovery of motor, sensory, autonomic, sexual, vasomotor and cognitive function |
| WO2014144785A1 (en) | 2013-03-15 | 2014-09-18 | The Regents Of The University Of California | Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion |
| CA2925754C (en) | 2013-09-27 | 2023-02-21 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
| US10751533B2 (en) | 2014-08-21 | 2020-08-25 | The Regents Of The University Of California | Regulation of autonomic control of bladder voiding after a complete spinal cord injury |
| EP3185946B1 (en) | 2014-08-27 | 2019-10-09 | The Regents Of The University Of California | Multi-electrode array for spinal cord epidural stimulation |
| US11298533B2 (en) | 2015-08-26 | 2022-04-12 | The Regents Of The University Of California | Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject |
| US11097122B2 (en) | 2015-11-04 | 2021-08-24 | The Regents Of The University Of California | Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel |
| EP3573517B1 (en) * | 2017-01-24 | 2023-10-18 | The Regents of the University of California | Accessing spinal network to enable respiratory function |
| WO2018148844A1 (en) | 2017-02-17 | 2018-08-23 | The University Of British Columbia | Apparatus and methods for maintaining physiological functions |
| US12434068B2 (en) | 2017-05-23 | 2025-10-07 | The Regents Of The University Of California | Accessing spinal networks to address sexual dysfunction |
| DE20168827T1 (de) | 2017-06-30 | 2021-01-21 | Gtx Medical B.V. | System zur neuromodulierung |
| WO2019050896A2 (en) * | 2017-09-05 | 2019-03-14 | University Of Florida Research Foundation, Inc. | STIMULATION OF NEURONES MOTORS OF SPINAL CORD BY ELECTRICAL SIGNALS |
| US12357828B2 (en) | 2017-12-05 | 2025-07-15 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for planning and/or providing neuromodulation |
| US11992684B2 (en) | 2017-12-05 | 2024-05-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | System for planning and/or providing neuromodulation |
| KR102118530B1 (ko) * | 2018-02-23 | 2020-06-03 | 김민규 | 펄스 자기장을 이용한 미주신경 자극 방법 및 장치 |
| US12478777B2 (en) | 2018-08-23 | 2025-11-25 | The Regents Of The University Of California | Non-invasive spinal cord stimulation for nerve root palsy, cauda equina syndrome, and restoration of upper extremity function |
| EP3653256B1 (en) | 2018-11-13 | 2022-03-30 | ONWARD Medical N.V. | Control system for movement reconstruction and/or restoration for a patient |
| EP3695878B1 (en) | 2019-02-12 | 2023-04-19 | ONWARD Medical N.V. | A system for neuromodulation |
| EP3972683A4 (en) | 2019-05-22 | 2023-11-08 | The Regents Of The University Of California | TRANSCUTANEOUS ELECTRICAL SPINAL CORD NEUROMODULATOR AND USES THEREOF |
| EP3824948A1 (en) | 2019-11-19 | 2021-05-26 | ONWARD Medical B.V. | A planning and/or control system for a neuromodulation system |
| EP3827871A1 (en) | 2019-11-27 | 2021-06-02 | ONWARD Medical B.V. | Neuromodulation system |
| DE19211738T1 (de) | 2019-11-27 | 2021-09-09 | Onward Medical B.V. | Neuromodulationssystem |
| EP3875142A1 (en) * | 2020-03-04 | 2021-09-08 | ONWARD Medical B.V. | A neuromodulation system |
| US12168096B2 (en) * | 2021-01-27 | 2024-12-17 | Chimei Medical Center | Ventilator-weaning timing prediction system, program product thereof and method for building and using the same |
| JP2024513975A (ja) * | 2021-04-14 | 2024-03-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 呼吸筋をコンディショニングするための脊髄刺激療法 |
| US12623080B2 (en) | 2023-06-21 | 2026-05-12 | Onward Medical N.V. | Neuromodulation system |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5066272A (en) | 1990-06-29 | 1991-11-19 | The Johns Hopkins University | Magnetic nerve stimulator |
| US6086525A (en) | 1994-11-28 | 2000-07-11 | Neotonus, Inc. | Magnetic nerve stimulator for exciting peripheral nerves |
| US6500110B1 (en) | 1996-08-15 | 2002-12-31 | Neotonus, Inc. | Magnetic nerve stimulation seat device |
| US6463327B1 (en) * | 1998-06-11 | 2002-10-08 | Cprx Llc | Stimulatory device and methods to electrically stimulate the phrenic nerve |
| US6234985B1 (en) * | 1998-06-11 | 2001-05-22 | Cprx Llc | Device and method for performing cardiopulmonary resuscitation |
| US7146221B2 (en) | 2001-11-16 | 2006-12-05 | The Regents Of The University Of California | Flexible electrode array for artifical vision |
| US20110288609A1 (en) * | 2003-10-15 | 2011-11-24 | Rmx, Llc | Therapeutic diaphragm stimulation device and method |
| US7422555B2 (en) * | 2003-12-30 | 2008-09-09 | Jacob Zabara | Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses |
| EP1750799A2 (en) * | 2004-05-04 | 2007-02-14 | The Cleveland Clinic Foundation | Methods of treating medical conditions by neuromodulation of the sympathetic nervous system |
| WO2005114720A2 (en) | 2004-05-14 | 2005-12-01 | California Institute Of Technology | Parylene-based flexible multi-electrode arrays for neuronal stimulation and recording and methods for manufacturing the same |
| US20070060954A1 (en) * | 2005-02-25 | 2007-03-15 | Tracy Cameron | Method of using spinal cord stimulation to treat neurological disorders or conditions |
| US7657316B2 (en) * | 2005-02-25 | 2010-02-02 | Boston Scientific Neuromodulation Corporation | Methods and systems for stimulating a motor cortex of the brain to treat a medical condition |
| US7702385B2 (en) * | 2005-11-16 | 2010-04-20 | Boston Scientific Neuromodulation Corporation | Electrode contact configurations for an implantable stimulator |
| WO2006102591A2 (en) * | 2005-03-24 | 2006-09-28 | Vanderbilt University | Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis |
| US8036750B2 (en) * | 2005-06-13 | 2011-10-11 | Cardiac Pacemakers, Inc. | System for neural control of respiration |
| CN1879906A (zh) | 2005-06-15 | 2006-12-20 | 郑云峰 | 中枢神经系统磁刺激装置及其使用方法 |
| US8676324B2 (en) | 2005-11-10 | 2014-03-18 | ElectroCore, LLC | Electrical and magnetic stimulators used to treat migraine/sinus headache, rhinitis, sinusitis, rhinosinusitis, and comorbid disorders |
| US8099146B1 (en) | 2006-03-23 | 2012-01-17 | Pacesetter, Inc. | System and method for calibrating a blood oxygen saturation sensor for use with an implantable medical device |
| US20090108969A1 (en) | 2007-10-31 | 2009-04-30 | Los Alamos National Security | Apparatus and method for transcranial and nerve magnetic stimulation |
| US8352036B2 (en) * | 2009-01-19 | 2013-01-08 | Anthony DiMarco | Respiratory muscle activation by spinal cord stimulation |
| JP2012519574A (ja) * | 2009-03-09 | 2012-08-30 | カーディアック ペースメイカーズ， インコーポレイテッド | リンパ管に埋め込み可能な電極を含む自律神経調整のためのシステム |
| US9403001B2 (en) | 2009-03-20 | 2016-08-02 | ElectroCore, LLC | Non-invasive magnetic or electrical nerve stimulation to treat gastroparesis, functional dyspepsia, and other functional gastrointestinal disorders |
| US9174045B2 (en) | 2009-03-20 | 2015-11-03 | ElectroCore, LLC | Non-invasive electrical and magnetic nerve stimulators used to treat overactive bladder and urinary incontinence |
| CA2823592C (en) | 2011-01-03 | 2021-11-23 | The Regents Of The University Of California | High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury |
| CN103608067A (zh) | 2011-01-21 | 2014-02-26 | 加利福尼亚理工学院 | 脊髓刺激法的聚对二甲苯基微电极阵列植入 |
| US10173048B2 (en) * | 2011-03-10 | 2019-01-08 | Electrocore, Inc. | Electrical and magnetic stimulators used to treat migraine/sinus headache, rhinitis, sinusitis, rhinosinusitis, and comorbid disorders |
| US9808164B2 (en) | 2011-09-30 | 2017-11-07 | Medtronic, Inc. | Evaluation of cardiac dyssynchrony based on chest wall motion and electrical cardiac activity |
| JP6359528B2 (ja) * | 2012-06-21 | 2018-07-18 | ラングペーサー メディカル インコーポレイテッドＬｕｎｇｐａｃｅｒ Ｍｅｄｉｃａｌ Ｉｎｃ． | 経血管横隔膜ペーシング・システム及び使用方法 |
| WO2014144785A1 (en) * | 2013-03-15 | 2014-09-18 | The Regents Of The University Of California | Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion |
| CA2925754C (en) * | 2013-09-27 | 2023-02-21 | The Regents Of The University Of California | Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects |
| EP3185946B1 (en) * | 2014-08-27 | 2019-10-09 | The Regents Of The University Of California | Multi-electrode array for spinal cord epidural stimulation |
| CN107405481A (zh) * | 2014-08-27 | 2017-11-28 | 加利福尼亚大学董事会 | 制造用于脊髓硬膜外刺激的多电极阵列的方法 |
-
2016
- 2016-07-11 EP EP16825005.8A patent/EP3322477B1/en active Active
- 2016-07-11 WO PCT/US2016/041802 patent/WO2017011410A1/en not_active Ceased
- 2016-07-11 JP JP2018501208A patent/JP6983148B2/ja active Active
- 2016-07-11 EP EP25221547.0A patent/EP4710997A3/en active Pending
- 2016-07-11 HK HK18114836.9A patent/HK1255688A1/zh unknown
- 2016-07-11 CA CA3030615A patent/CA3030615A1/en active Pending
- 2016-07-11 US US15/740,323 patent/US20180185642A1/en active Pending
-
2021
- 2021-11-19 JP JP2021188658A patent/JP7520800B2/ja active Active
-
2025
- 2025-06-04 US US19/227,985 patent/US20250295923A1/en active Pending
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