DE602006012327D1 - Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems - Google Patents

Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems

Info

Publication number
DE602006012327D1
DE602006012327D1 DE602006012327T DE602006012327T DE602006012327D1 DE 602006012327 D1 DE602006012327 D1 DE 602006012327D1 DE 602006012327 T DE602006012327 T DE 602006012327T DE 602006012327 T DE602006012327 T DE 602006012327T DE 602006012327 D1 DE602006012327 D1 DE 602006012327D1
Authority
DE
Germany
Prior art keywords
nervous system
functional restoration
damaged nervous
microelectrodes
bridging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006012327T
Other languages
English (en)
Inventor
Carmen Bartic
Jean-Pierre Kruth
Bart Nuttin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KU Leuven Research and Development
Original Assignee
KU Leuven Research and Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0513460A external-priority patent/GB0513460D0/en
Priority claimed from GB0513684A external-priority patent/GB0513684D0/en
Application filed by KU Leuven Research and Development filed Critical KU Leuven Research and Development
Publication of DE602006012327D1 publication Critical patent/DE602006012327D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36103—Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/407—Evaluating the spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
    • A61B6/50—Clinical applications
    • A61B6/506—Clinical applications involving diagnosis of nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0531—Brain cortex electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
DE602006012327T 2005-07-01 2006-07-03 Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems Active DE602006012327D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0513460A GB0513460D0 (en) 2005-07-01 2005-07-01 Functional restoration of the damaged nervous system
GB0513684A GB0513684D0 (en) 2005-07-05 2005-07-05 Functional restoration of the damaged nervous system
PCT/BE2006/000077 WO2007003019A2 (en) 2005-07-01 2006-07-03 Means for functional restoration of a damaged nervous system

Publications (1)

Publication Number Publication Date
DE602006012327D1 true DE602006012327D1 (de) 2010-04-01

Family

ID=37240989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006012327T Active DE602006012327D1 (de) 2005-07-01 2006-07-03 Mittel zur funktionalen wiederherstellung eines geschädigten nervensystems

Country Status (8)

Country Link
US (1) US7991465B2 (de)
EP (1) EP1909890B1 (de)
JP (1) JP4880681B2 (de)
AT (1) ATE457773T1 (de)
CA (1) CA2613694A1 (de)
DE (1) DE602006012327D1 (de)
DK (1) DK1909890T3 (de)
WO (1) WO2007003019A2 (de)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2672731C (en) 2006-12-15 2013-02-26 Nasophlex B.V. Resuscitation device and method for resuscitation
WO2008107822A1 (en) * 2007-03-02 2008-09-12 Koninklijke Philips Electronics N.V. Electrode system for deep brain stimulation
DE102007029364A1 (de) * 2007-06-26 2009-01-02 Siemens Ag Verfahren zum Bestimmen eines Zugangs zu einem Areal von einem Gehirn
JP5126710B2 (ja) * 2007-08-22 2013-01-23 国立大学法人大阪大学 頭蓋内電極構造体およびその製造方法
NL2001697C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Nose stimulator for producing a stimulation signal to a nose.
NL2001695C2 (en) * 2008-06-18 2009-12-22 Kerphos B V An electronic system for producing a stimulation signal to the human body.
NL2001694C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Ear stimulator for producing a stimulation signal to an ear.
NL2001698C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Cardioverter / defibrillator.
CA2739431C (en) 2008-10-01 2016-12-06 Sherwin Hua System and method for wire-guided pedicle screw stabilization of spinal vertebrae
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
EP2349440B1 (de) 2008-10-07 2019-08-21 Mc10, Inc. Katheterballon mit dehnbarer integrierter schaltung und sensoranordnung
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9123614B2 (en) 2008-10-07 2015-09-01 Mc10, Inc. Methods and applications of non-planar imaging arrays
US9545216B2 (en) 2011-08-05 2017-01-17 Mc10, Inc. Catheter balloon methods and apparatus employing sensing elements
US8992568B2 (en) 2008-10-20 2015-03-31 Neil Duggal Systems and methods for cerebrospinal fluid repair
EP2184263A1 (de) 2008-11-06 2010-05-12 Unilever N.V. Wasseraufbereitungsvorrichtung
JP5694947B2 (ja) * 2008-12-11 2015-04-01 エムシー１０ インコーポレイテッドＭｃ１０，Ｉｎｃ． 医療用途のための伸張性電子部品を使用する装置
US9723122B2 (en) 2009-10-01 2017-08-01 Mc10, Inc. Protective cases with integrated electronics
US8666471B2 (en) 2010-03-17 2014-03-04 The Board Of Trustees Of The University Of Illinois Implantable biomedical devices on bioresorbable substrates
EP2353636A1 (de) * 2010-02-05 2011-08-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Neurologische Schnittstellensonde
US8718792B2 (en) * 2010-02-19 2014-05-06 Neuron Networks Restored, Llc System and method of repairing of neural networks
WO2011107917A1 (en) * 2010-03-01 2011-09-09 Koninklijke Philips Electronics N.V. Method and system for determining settings for deep brain stimulation
DE102010020610A1 (de) * 2010-05-14 2011-11-17 Siemens Aktiengesellschaft Strahlendetektor und Verfahren zur Herstellung eines Strahlendetektors
US11813454B2 (en) * 2010-11-11 2023-11-14 IINN, Inc. Methods of bypassing neurological damage through motor nerve root stimulation
WO2012094346A2 (en) 2011-01-03 2012-07-12 The Regents Of The University Of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
WO2012100260A2 (en) 2011-01-21 2012-07-26 California Institute Of Technology A parylene-based microelectrode array implant for spinal cord stimulation
JP6060146B2 (ja) 2011-03-24 2017-01-11 カリフォルニア インスティテュート オブ テクノロジー 神経刺激装置
JP5771437B2 (ja) * 2011-04-26 2015-08-26 学校法人同志社 生体装着用電極
JP2014523633A (ja) 2011-05-27 2014-09-11 エムシー１０ インコーポレイテッド 電子的、光学的、且つ／又は機械的装置及びシステム並びにこれらの装置及びシステムを製造する方法
US9757050B2 (en) 2011-08-05 2017-09-12 Mc10, Inc. Catheter balloon employing force sensing elements
WO2013052180A2 (en) 2011-10-05 2013-04-11 University Of Kansas Methods and associated neural prosthetic devices for bridging brain areas to improve function
JP2014533183A (ja) 2011-11-11 2014-12-11 ニューロイネイブリング テクノロジーズ インコーポレイテッド 運動神経、感覚、自律、性的、血管運動および認知機能の回復を可能にするための非侵襲性神経調節装置
AU2012334926B2 (en) 2011-11-11 2017-07-13 The Regents Of The University Of California Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
US10092750B2 (en) 2011-11-11 2018-10-09 Neuroenabling Technologies, Inc. Transcutaneous neuromodulation system and methods of using same
US9226402B2 (en) 2012-06-11 2015-12-29 Mc10, Inc. Strain isolation structures for stretchable electronics
WO2014007871A1 (en) 2012-07-05 2014-01-09 Mc10, Inc. Catheter device including flow sensing
US9295842B2 (en) 2012-07-05 2016-03-29 Mc10, Inc. Catheter or guidewire device including flow sensing and use thereof
EP2906960A4 (de) 2012-10-09 2016-06-15 Mc10 Inc Kleidung mit integrierter konformer elektronik
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
US9993642B2 (en) 2013-03-15 2018-06-12 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
US9919146B2 (en) 2013-05-01 2018-03-20 Sherwin Hua Methods and systems for intraventricular brain stimulation
US9706647B2 (en) 2013-05-14 2017-07-11 Mc10, Inc. Conformal electronics including nested serpentine interconnects
CN105723197A (zh) 2013-08-05 2016-06-29 Mc10股份有限公司 包括可适形电子器件的柔性温度传感器
US10137299B2 (en) 2013-09-27 2018-11-27 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
KR20160065948A (ko) 2013-10-07 2016-06-09 엠씨10, 인크 감지 및 분석용 등각 센서 시스템
CA2930740A1 (en) 2013-11-22 2015-05-28 Mc10, Inc. Conformal sensor systems for sensing and analysis of cardiac activity
EP3092661A4 (de) 2014-01-06 2017-09-27 Mc10, Inc. Verkapselte elektronische konforme systeme und vorrichtungen sowie verfahren zur herstellung und verwendung davon
WO2015106286A1 (en) 2014-01-13 2015-07-16 California Institute Of Technology Neuromodulation systems and methods of using same
EP3114911B1 (de) 2014-03-04 2023-05-03 Medidata Solutions, Inc. Flexibles mehrteiliges verkapselungsgehäuse für elektronische vorrichtungen
US9486878B2 (en) 2014-06-20 2016-11-08 Velo3D, Inc. Apparatuses, systems and methods for three-dimensional printing
WO2016029159A2 (en) 2014-08-21 2016-02-25 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
CA2959378A1 (en) 2014-08-27 2016-03-03 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
US9899330B2 (en) 2014-10-03 2018-02-20 Mc10, Inc. Flexible electronic circuits with embedded integrated circuit die
US10297572B2 (en) 2014-10-06 2019-05-21 Mc10, Inc. Discrete flexible interconnects for modules of integrated circuits
USD781270S1 (en) 2014-10-15 2017-03-14 Mc10, Inc. Electronic device having antenna
WO2016126795A1 (en) * 2015-02-03 2016-08-11 Children's Medical Center Corporation Detecting nerve damage using diffusion tensor imaging
CN107530004A (zh) 2015-02-20 2018-01-02 Mc10股份有限公司 基于贴身状况、位置和/或取向的可穿戴式设备的自动检测和构造
WO2016140961A1 (en) 2015-03-02 2016-09-09 Mc10, Inc. Perspiration sensor
US10653332B2 (en) 2015-07-17 2020-05-19 Mc10, Inc. Conductive stiffener, method of making a conductive stiffener, and conductive adhesive and encapsulation layers
US10709384B2 (en) 2015-08-19 2020-07-14 Mc10, Inc. Wearable heat flux devices and methods of use
WO2017035512A1 (en) 2015-08-26 2017-03-02 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
EP3356003A4 (de) 2015-10-01 2019-04-03 Mc10, Inc. Verfahren und system zur interaktion mit einer virtuellen umgebung
CN108289630A (zh) 2015-10-05 2018-07-17 Mc10股份有限公司 用于神经调节和刺激的方法和系统
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
CN108367498A (zh) 2015-11-06 2018-08-03 维洛3D公司 Adept三维打印
CN108698126A (zh) 2015-12-10 2018-10-23 维洛3D公司 精湛的三维打印
WO2017143077A1 (en) 2016-02-18 2017-08-24 Velo3D, Inc. Accurate three-dimensional printing
US10673280B2 (en) 2016-02-22 2020-06-02 Mc10, Inc. System, device, and method for coupled hub and sensor node on-body acquisition of sensor information
EP3420732B8 (de) 2016-02-22 2020-12-30 Medidata Solutions, Inc. System, vorrichtungen und verfahren zur daten- und leistungsübertragung auf dem körper
EP3445230B1 (de) 2016-04-19 2024-03-13 Medidata Solutions, Inc. Verfahren und system zur messung der transpiration
WO2018005439A1 (en) 2016-06-29 2018-01-04 Velo3D, Inc. Three-dimensional printing and three-dimensional printers
US11691343B2 (en) 2016-06-29 2023-07-04 Velo3D, Inc. Three-dimensional printing and three-dimensional printers
US20210290949A1 (en) * 2016-07-28 2021-09-23 Galvani Bioelectronics Limited Nerve cuffs, methods of fabricating the same and methods of use
US10447347B2 (en) 2016-08-12 2019-10-15 Mc10, Inc. Wireless charger and high speed data off-loader
WO2018128695A2 (en) 2016-11-07 2018-07-12 Velo3D, Inc. Gas flow in three-dimensional printing
US10611092B2 (en) 2017-01-05 2020-04-07 Velo3D, Inc. Optics in three-dimensional printing
US10442003B2 (en) 2017-03-02 2019-10-15 Velo3D, Inc. Three-dimensional printing of three-dimensional objects
WO2018183396A1 (en) 2017-03-28 2018-10-04 Velo3D, Inc. Material manipulation in three-dimensional printing
DE20168827T1 (de) 2017-06-30 2021-01-21 Gtx Medical B.V. System zur neuromodulierung
US11407034B2 (en) 2017-07-06 2022-08-09 OmniTek Technology Ltda. Selective laser melting system and method of using same
US10272525B1 (en) 2017-12-27 2019-04-30 Velo3D, Inc. Three-dimensional printing systems and methods of their use
US10144176B1 (en) 2018-01-15 2018-12-04 Velo3D, Inc. Three-dimensional printing systems and methods of their use
EP3653260A1 (de) 2018-11-13 2020-05-20 GTX medical B.V. Sensor in bekleidung von gliedmassen oder schuhwerk
DE18205821T1 (de) 2018-11-13 2020-12-24 Gtx Medical B.V. Steuerungssystem zur bewegungsrekonstruktion und/oder wiederherstellung für einen patienten
EP3695878B1 (de) 2019-02-12 2023-04-19 ONWARD Medical N.V. System zur neuromodulierung
CN110694169A (zh) * 2019-09-16 2020-01-17 浙江大学 基于运动意图诱发中枢神经系统微电刺激的运动功能障碍神经桥接系统
EP3827871A1 (de) 2019-11-27 2021-06-02 ONWARD Medical B.V. Neuromodulationssystem
US20220331565A1 (en) * 2021-04-14 2022-10-20 The Board Of Trustees Of The University Of Arkansas Patient specific medical balloon forming machine and system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262945A (en) 1991-08-09 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Method for quantification of brain volume from magnetic resonance images
US6176874B1 (en) 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US6327491B1 (en) 1998-07-06 2001-12-04 Neutar, Llc Customized surgical fixture
ATE282661T1 (de) * 1998-08-26 2004-12-15 Dow Global Technologies Inc Internes formtrennmittel für rim- polyurethanschaumstoffe niedriger dichte
US20020187350A1 (en) * 2001-01-29 2002-12-12 Honeywell International Inc. Robust highly reflective optical construction
US7072436B2 (en) * 2001-08-24 2006-07-04 The Board Of Trustees Of The Leland Stanford Junior University Volumetric computed tomography (VCT)
US6976998B2 (en) * 2002-01-17 2005-12-20 Massachusetts Institute Of Technology Minimally invasive retinal prosthesis
US6734096B2 (en) 2002-01-17 2004-05-11 International Business Machines Corporation Fine-pitch device lithography using a sacrificial hardmask
US7012266B2 (en) 2002-08-23 2006-03-14 Samsung Electronics Co., Ltd. MEMS-based two-dimensional e-beam nano lithography device and method for making the same
US7369900B2 (en) * 2004-05-08 2008-05-06 Bojan Zdravkovic Neural bridge devices and methods for restoring and modulating neural activity

Also Published As

Publication number Publication date
EP1909890A2 (de) 2008-04-16
CA2613694A1 (en) 2007-01-11
ATE457773T1 (de) 2010-03-15
EP1909890B1 (de) 2010-02-17
WO2007003019A2 (en) 2007-01-11
US20080208268A1 (en) 2008-08-28
JP2008546491A (ja) 2008-12-25
US7991465B2 (en) 2011-08-02
JP4880681B2 (ja) 2012-02-22
DK1909890T3 (da) 2010-05-03
WO2007003019A3 (en) 2007-03-01

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