WO2007133718A3 - Non-invasive acquisition of large nerve action potentials (naps) with closely spaced surface electrodes and reduced stimulus artifacts - Google Patents

Non-invasive acquisition of large nerve action potentials (naps) with closely spaced surface electrodes and reduced stimulus artifacts Download PDF

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Publication number
WO2007133718A3
WO2007133718A3 PCT/US2007/011483 US2007011483W WO2007133718A3 WO 2007133718 A3 WO2007133718 A3 WO 2007133718A3 US 2007011483 W US2007011483 W US 2007011483W WO 2007133718 A3 WO2007133718 A3 WO 2007133718A3
Authority
WO
WIPO (PCT)
Prior art keywords
naps
action potentials
closely spaced
nerve action
surface electrodes
Prior art date
Application number
PCT/US2007/011483
Other languages
French (fr)
Other versions
WO2007133718A2 (en
Inventor
Changwang Wu
Shai Gozani
Original Assignee
Neurometrix Inc
Changwang Wu
Shai Gozani
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurometrix Inc, Changwang Wu, Shai Gozani filed Critical Neurometrix Inc
Publication of WO2007133718A2 publication Critical patent/WO2007133718A2/en
Publication of WO2007133718A3 publication Critical patent/WO2007133718A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0456—Specially adapted for transcutaneous electrical nerve stimulation [TENS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0492—Patch electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

The present invention addresses the foregoing problems associated with the prior art by providing a novel method and apparatus (5) for, non-invasively detecting large nerve action potentials (NAPs) while effectively minimizing or substantially eliminating stimulus artifacts, even where the stimulation site ( 15, 20) and the detection site (25, 30) are in close physical proximity (80) to one another, e g, within about 2 cm of one another.
PCT/US2007/011483 2006-05-11 2007-05-11 Non-invasive acquisition of large nerve action potentials (naps) with closely spaced surface electrodes and reduced stimulus artifacts WO2007133718A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US79951206P 2006-05-11 2006-05-11
US60/799,512 2006-05-11
US87529206P 2006-12-15 2006-12-15
US60/875,292 2006-12-15

Publications (2)

Publication Number Publication Date
WO2007133718A2 WO2007133718A2 (en) 2007-11-22
WO2007133718A3 true WO2007133718A3 (en) 2008-11-27

Family

ID=38694514

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/011483 WO2007133718A2 (en) 2006-05-11 2007-05-11 Non-invasive acquisition of large nerve action potentials (naps) with closely spaced surface electrodes and reduced stimulus artifacts

Country Status (1)

Country Link
WO (1) WO2007133718A2 (en)

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US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
WO2009029614A1 (en) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
US9211409B2 (en) 2008-03-31 2015-12-15 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of T-cell activity
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
EP2355893B1 (en) * 2008-11-18 2013-12-25 Setpoint Medical Corporation Devices for optimizing electrode placement for anti-inflamatory stimulation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
WO2010144578A2 (en) 2009-06-09 2010-12-16 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
WO2014169145A1 (en) 2013-04-10 2014-10-16 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
EP2515996B1 (en) 2009-12-23 2019-09-18 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
WO2012154865A2 (en) 2011-05-09 2012-11-15 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
CN108882885A (en) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 The control of vagal stimulation
EP3405255A4 (en) 2016-01-20 2019-10-16 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US11173307B2 (en) 2017-08-14 2021-11-16 Setpoint Medical Corporation Vagus nerve stimulation pre-screening test
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
EP3744277B1 (en) * 2019-05-27 2024-09-11 Erbe Elektromedizin GmbH Method and device for quantifying neuromuscular inflammation due to hf flows
JP2023526080A (en) 2020-05-21 2023-06-20 ザ・フェインステイン・インスティチュート・フォー・メディカル・リサーチ Systems and methods for vagus nerve stimulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5758651A (en) * 1992-12-22 1998-06-02 Nygard; Tony Mikeal Telemetry system and apparatus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5758651A (en) * 1992-12-22 1998-06-02 Nygard; Tony Mikeal Telemetry system and apparatus

Also Published As

Publication number Publication date
WO2007133718A2 (en) 2007-11-22

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