JP2018505153A5 - - Google Patents
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- JP2018505153A5 JP2018505153A5 JP2017534915A JP2017534915A JP2018505153A5 JP 2018505153 A5 JP2018505153 A5 JP 2018505153A5 JP 2017534915 A JP2017534915 A JP 2017534915A JP 2017534915 A JP2017534915 A JP 2017534915A JP 2018505153 A5 JP2018505153 A5 JP 2018505153A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- amino acid
- receptor
- pharmaceutical composition
- receptor agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2014-0193691 | 2014-12-30 | ||
| KR1020140193691A KR102418477B1 (ko) | 2014-12-30 | 2014-12-30 | 글루카곤 유도체 |
| PCT/KR2015/014481 WO2016108617A1 (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018505153A JP2018505153A (ja) | 2018-02-22 |
| JP2018505153A5 true JP2018505153A5 (enExample) | 2019-01-31 |
| JP6758297B2 JP6758297B2 (ja) | 2020-09-23 |
Family
ID=56284668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534915A Active JP6758297B2 (ja) | 2014-12-30 | 2015-12-30 | グルカゴン誘導体 |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US10513550B2 (enExample) |
| EP (1) | EP3240802B1 (enExample) |
| JP (1) | JP6758297B2 (enExample) |
| KR (1) | KR102418477B1 (enExample) |
| CN (1) | CN107250155B (enExample) |
| AR (1) | AR103323A1 (enExample) |
| AU (1) | AU2015372767B2 (enExample) |
| BR (1) | BR112017013845A2 (enExample) |
| CA (1) | CA2972001C (enExample) |
| EA (1) | EA036479B1 (enExample) |
| IL (1) | IL253001B (enExample) |
| MX (1) | MX389593B (enExample) |
| PH (1) | PH12017501205A1 (enExample) |
| SG (2) | SG10201906912VA (enExample) |
| TW (1) | TWI696631B (enExample) |
| UA (1) | UA122967C2 (enExample) |
| WO (1) | WO2016108617A1 (enExample) |
| ZA (1) | ZA201704328B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20230304A1 (es) * | 2014-12-30 | 2023-02-13 | Hanmi Pharm Ind Co Ltd | Derivados de glucagon como agentes hipoglucemicos y antiobesidad |
| CN108025041A (zh) | 2015-06-30 | 2018-05-11 | 韩美药品株式会社 | 胰高血糖素衍生物和包含其长效缀合物的组合物 |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| HK1258177A1 (en) | 2015-12-31 | 2019-11-08 | Hanmi Pharm. Co., Ltd. | Persistent conjugate of triple activator activating glucagon, glp-1 and gip receptor |
| CN112912095A (zh) * | 2018-07-19 | 2021-06-04 | D&D制药技术股份有限公司 | 包括多肽的药物组合物 |
| JP2025526148A (ja) | 2022-08-18 | 2025-08-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療 |
Family Cites Families (88)
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| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| CA2249195A1 (en) | 1996-03-18 | 1997-09-25 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
| JP3895109B2 (ja) | 1998-03-06 | 2007-03-22 | 中外製薬株式会社 | 蛋白非添加製剤 |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| US6677136B2 (en) | 2000-05-03 | 2004-01-13 | Amgen Inc. | Glucagon antagonists |
| GB0121709D0 (en) | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| WO2005003296A2 (en) | 2003-01-22 | 2005-01-13 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| US7217845B2 (en) | 2002-11-25 | 2007-05-15 | Sun Bio, Inc. | Bifunctional polyethylene glycol derivatives |
| GB0300571D0 (en) | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US20050176108A1 (en) | 2003-03-13 | 2005-08-11 | Young-Min Kim | Physiologically active polypeptide conjugate having prolonged in vivo half-life |
| WO2005035761A1 (en) | 2003-10-16 | 2005-04-21 | Compugen Ltd. | Splice variants of preproglucagon, glucagon-like peptide-1 and oxyntomodulin |
| US8263084B2 (en) | 2003-11-13 | 2012-09-11 | Hanmi Science Co., Ltd | Pharmaceutical composition for treating obesity-related disease comprising insulinotropic peptide conjugate |
| AU2004282984B2 (en) | 2003-11-13 | 2011-07-14 | Hanmi Science Co., Ltd. | Protein complex using immunoglobulin fragment andmethod for the preparation thereof |
| US20090238838A1 (en) | 2003-11-13 | 2009-09-24 | Hanmi Pharm. Ind. Co. Ltd. | Insulinotropic peptide conjugate using an immunoglobulin fc |
| KR101135244B1 (ko) | 2007-11-29 | 2012-04-24 | 한미사이언스 주식회사 | 인슐린 분비 펩타이드 결합체를 포함하는 비만 관련질환 치료용 조성물 |
| CA2589800A1 (en) | 2004-12-02 | 2006-06-08 | Domantis Limited | Bispecific domain antibodies targeting serum albumin and glp-1 or pyy |
| EA011653B1 (ru) | 2005-02-11 | 2009-04-28 | Амилин Фармасьютикалз, Инк. | Аналоги и гибридные полипептиды gip с избираемыми свойствами |
| US20090286723A1 (en) | 2005-02-11 | 2009-11-19 | Amylin Pharmaceuticals, Inc. | Hybrid Polypeptides with Selectable Properties |
| KR100754667B1 (ko) | 2005-04-08 | 2007-09-03 | 한미약품 주식회사 | 비펩타이드성 중합체로 개질된 면역글로불린 Ｆｃ 단편 및이를 포함하는 약제학적 조성물 |
| AU2006258841B2 (en) | 2005-06-13 | 2012-05-03 | Imperial Innovations Limited | Oxyntomodulin analogues and their effects on feeding behaviour |
| GB0511986D0 (en) | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| WO2007030375A2 (en) | 2005-09-08 | 2007-03-15 | Children's Hospital Medical Center | Lysosomal acid lipase therapy for nafld and related diseases |
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