BR112017013845A2 - derivados de glucagon - Google Patents

derivados de glucagon

Info

Publication number
BR112017013845A2
BR112017013845A2 BR112017013845A BR112017013845A BR112017013845A2 BR 112017013845 A2 BR112017013845 A2 BR 112017013845A2 BR 112017013845 A BR112017013845 A BR 112017013845A BR 112017013845 A BR112017013845 A BR 112017013845A BR 112017013845 A2 BR112017013845 A2 BR 112017013845A2
Authority
BR
Brazil
Prior art keywords
glucagon
peptide
present
receptors
obesity
Prior art date
Application number
BR112017013845A
Other languages
English (en)
Inventor
Ki Lim Chang
Hyuk Choi Jae
Suk Lee Jong
Chang Kwon Se
Youb Jung Sung
Jin Park Young
Original Assignee
Hanmi Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanmi Pharm Ind Co Ltd filed Critical Hanmi Pharm Ind Co Ltd
Publication of BR112017013845A2 publication Critical patent/BR112017013845A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

a presente invenção se refere a um novo peptídeo de um derivado de glucagon e uma composição para prevenir ou tratar a obesidade compreendendo o peptídeo como um ingrediente ativo. o derivado do glucagon de acordo com a presente invenção mostra um efeito de ativação mais excelente tanto no que diz respeito aos receptores do peptídeo semelhante ao glucagon 1 como aos receptores de glucagon em comparação ao glucagon nativo, e assim pode ser amplamente utilizado como um agente eficaz para o tratamento da obesidade.
BR112017013845A 2014-12-30 2015-12-30 derivados de glucagon BR112017013845A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020140193691A KR102418477B1 (ko) 2014-12-30 2014-12-30 글루카곤 유도체
PCT/KR2015/014481 WO2016108617A1 (en) 2014-12-30 2015-12-30 Glucagon derivatives

Publications (1)

Publication Number Publication Date
BR112017013845A2 true BR112017013845A2 (pt) 2018-01-02

Family

ID=56284668

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017013845A BR112017013845A2 (pt) 2014-12-30 2015-12-30 derivados de glucagon

Country Status (19)

Country Link
US (2) US10513550B2 (pt)
EP (1) EP3240802B1 (pt)
JP (1) JP6758297B2 (pt)
KR (1) KR102418477B1 (pt)
CN (1) CN107250155B (pt)
AR (1) AR103323A1 (pt)
AU (1) AU2015372767B2 (pt)
BR (1) BR112017013845A2 (pt)
CA (1) CA2972001A1 (pt)
EA (1) EA036479B1 (pt)
HK (1) HK1246323A1 (pt)
IL (1) IL253001B (pt)
MX (1) MX2017008715A (pt)
PH (1) PH12017501205A1 (pt)
SG (2) SG11201705130XA (pt)
TW (1) TWI696631B (pt)
UA (1) UA122967C2 (pt)
WO (1) WO2016108617A1 (pt)
ZA (1) ZA201704328B (pt)

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TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
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WO2024038067A1 (en) 2022-08-18 2024-02-22 Boehringer Ingelheim International Gmbh Combination therapy comprising long acting glp-1/glucagon and npy2 receptor agonists

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EP3240802B1 (en) 2021-07-21
MX2017008715A (es) 2017-11-17
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US20220025012A1 (en) 2022-01-27
ZA201704328B (en) 2021-01-27
EP3240802A1 (en) 2017-11-08
WO2016108617A1 (en) 2016-07-07
JP6758297B2 (ja) 2020-09-23
CN107250155B (zh) 2021-08-10
US20200140515A1 (en) 2020-05-07
US10513550B2 (en) 2019-12-24

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