SG10201906912VA - Glucagon derivatives - Google Patents
Glucagon derivativesInfo
- Publication number
- SG10201906912VA SG10201906912VA SG10201906912VA SG10201906912VA SG10201906912VA SG 10201906912V A SG10201906912V A SG 10201906912VA SG 10201906912V A SG10201906912V A SG 10201906912VA SG 10201906912V A SG10201906912V A SG 10201906912VA SG 10201906912V A SG10201906912V A SG 10201906912VA
- Authority
- SG
- Singapore
- Prior art keywords
- glucagon
- peptide
- present
- treating obesity
- receptors
- Prior art date
Links
- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical class C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 5
- 208000008589 Obesity Diseases 0.000 abstract 2
- 235000020824 obesity Nutrition 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000051325 Glucagon Human genes 0.000 abstract 1
- 108060003199 Glucagon Proteins 0.000 abstract 1
- 108010063919 Glucagon Receptors Proteins 0.000 abstract 1
- 102100040890 Glucagon receptor Human genes 0.000 abstract 1
- 108010086246 Glucagon-Like Peptide-1 Receptor Proteins 0.000 abstract 1
- 102100032882 Glucagon-like peptide 1 receptor Human genes 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229960004666 glucagon Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
GLUCAGON DERIVATIVES The present invention relates to a novel peptide of a glucagon derivative and a composition for preventing or treating obesity comprising the peptide as an active ingredient. The glucagon derivative according to the present invention shows a more excellent activating effect with regard to both glucagon-like peptide-1 receptors and glucagon receptors compared to native glucagon, and thus can be widely used as an effective agent for treating obesity. NO FIGURE
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020140193691A KR102418477B1 (en) | 2014-12-30 | 2014-12-30 | Gluagon Derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201906912VA true SG10201906912VA (en) | 2019-09-27 |
Family
ID=56284668
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201705130XA SG11201705130XA (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
SG10201906912VA SG10201906912VA (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201705130XA SG11201705130XA (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
Country Status (19)
Country | Link |
---|---|
US (3) | US10513550B2 (en) |
EP (1) | EP3240802B1 (en) |
JP (1) | JP6758297B2 (en) |
KR (1) | KR102418477B1 (en) |
CN (1) | CN107250155B (en) |
AR (1) | AR103323A1 (en) |
AU (1) | AU2015372767B2 (en) |
BR (1) | BR112017013845A2 (en) |
CA (1) | CA2972001A1 (en) |
EA (1) | EA036479B1 (en) |
HK (1) | HK1246323A1 (en) |
IL (1) | IL253001B (en) |
MX (1) | MX2017008715A (en) |
PH (1) | PH12017501205A1 (en) |
SG (2) | SG11201705130XA (en) |
TW (1) | TWI696631B (en) |
UA (1) | UA122967C2 (en) |
WO (1) | WO2016108617A1 (en) |
ZA (1) | ZA201704328B (en) |
Families Citing this family (5)
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WO2016108586A1 (en) * | 2014-12-30 | 2016-07-07 | 한미약품 주식회사 | Glucagon derivative having improved stability |
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TWI622596B (en) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | Glucagon receptor agonists |
HRP20220995T1 (en) | 2015-12-31 | 2022-11-11 | Hanmi Pharm. Co., Ltd. | Triple activator activating glucagon, glp-1 and gip receptor |
WO2024038067A1 (en) | 2022-08-18 | 2024-02-22 | Boehringer Ingelheim International Gmbh | Combination therapy comprising long acting glp-1/glucagon and npy2 receptor agonists |
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2014
- 2014-12-30 KR KR1020140193691A patent/KR102418477B1/en active IP Right Grant
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2015
- 2015-12-30 EP EP15875711.2A patent/EP3240802B1/en active Active
- 2015-12-30 CN CN201580071897.XA patent/CN107250155B/en active Active
- 2015-12-30 UA UAA201707894A patent/UA122967C2/en unknown
- 2015-12-30 WO PCT/KR2015/014481 patent/WO2016108617A1/en active Application Filing
- 2015-12-30 AU AU2015372767A patent/AU2015372767B2/en active Active
- 2015-12-30 EA EA201791498A patent/EA036479B1/en not_active IP Right Cessation
- 2015-12-30 SG SG11201705130XA patent/SG11201705130XA/en unknown
- 2015-12-30 JP JP2017534915A patent/JP6758297B2/en active Active
- 2015-12-30 CA CA2972001A patent/CA2972001A1/en active Pending
- 2015-12-30 TW TW104144429A patent/TWI696631B/en active
- 2015-12-30 BR BR112017013845A patent/BR112017013845A2/en not_active Application Discontinuation
- 2015-12-30 SG SG10201906912VA patent/SG10201906912VA/en unknown
- 2015-12-30 US US15/539,238 patent/US10513550B2/en active Active
- 2015-12-30 AR ARP150104341A patent/AR103323A1/en unknown
- 2015-12-30 MX MX2017008715A patent/MX2017008715A/en unknown
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2017
- 2017-06-19 IL IL253001A patent/IL253001B/en unknown
- 2017-06-26 ZA ZA2017/04328A patent/ZA201704328B/en unknown
- 2017-06-27 PH PH12017501205A patent/PH12017501205A1/en unknown
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2018
- 2018-05-07 HK HK18105858.0A patent/HK1246323A1/en unknown
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2019
- 2019-11-14 US US16/684,110 patent/US11254724B2/en active Active
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2021
- 2021-10-12 US US17/499,222 patent/US12018060B2/en active Active
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