KR102418477B1 - 글루카곤 유도체 - Google Patents

글루카곤 유도체 Download PDF

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Publication number
KR102418477B1
KR102418477B1 KR1020140193691A KR20140193691A KR102418477B1 KR 102418477 B1 KR102418477 B1 KR 102418477B1 KR 1020140193691 A KR1020140193691 A KR 1020140193691A KR 20140193691 A KR20140193691 A KR 20140193691A KR 102418477 B1 KR102418477 B1 KR 102418477B1
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KR
South Korea
Prior art keywords
peptide
glucagon
receptor
obesity
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020140193691A
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English (en)
Korean (ko)
Other versions
KR20160082026A (ko
Inventor
정성엽
박영진
이종석
최재혁
임창기
권세창
Original Assignee
한미약품 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority to KR1020140193691A priority Critical patent/KR102418477B1/ko
Application filed by 한미약품 주식회사 filed Critical 한미약품 주식회사
Priority to EA201791498A priority patent/EA036479B1/ru
Priority to MX2017008715A priority patent/MX389593B/es
Priority to SG11201705130XA priority patent/SG11201705130XA/en
Priority to ARP150104341A priority patent/AR103323A1/es
Priority to BR112017013845A priority patent/BR112017013845A2/pt
Priority to NZ771617A priority patent/NZ771617B2/en
Priority to US15/539,238 priority patent/US10513550B2/en
Priority to TW104144429A priority patent/TWI696631B/zh
Priority to NZ733649A priority patent/NZ733649B2/en
Priority to EP15875711.2A priority patent/EP3240802B1/en
Priority to SG10201906912VA priority patent/SG10201906912VA/en
Priority to CA2972001A priority patent/CA2972001C/en
Priority to AU2015372767A priority patent/AU2015372767B2/en
Priority to UAA201707894A priority patent/UA122967C2/uk
Priority to HK18105858.0A priority patent/HK1246323B/en
Priority to PCT/KR2015/014481 priority patent/WO2016108617A1/en
Priority to JP2017534915A priority patent/JP6758297B2/ja
Priority to CN201580071897.XA priority patent/CN107250155B/zh
Publication of KR20160082026A publication Critical patent/KR20160082026A/ko
Priority to IL253001A priority patent/IL253001B/en
Priority to ZA2017/04328A priority patent/ZA201704328B/en
Priority to PH12017501205A priority patent/PH12017501205A1/en
Priority to US16/684,110 priority patent/US11254724B2/en
Priority to US17/499,222 priority patent/US12018060B2/en
Application granted granted Critical
Publication of KR102418477B1 publication Critical patent/KR102418477B1/ko
Active legal-status Critical Current
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020140193691A 2014-12-30 2014-12-30 글루카곤 유도체 Active KR102418477B1 (ko)

Priority Applications (24)

Application Number Priority Date Filing Date Title
KR1020140193691A KR102418477B1 (ko) 2014-12-30 2014-12-30 글루카곤 유도체
AU2015372767A AU2015372767B2 (en) 2014-12-30 2015-12-30 Glucagon derivatives
SG11201705130XA SG11201705130XA (en) 2014-12-30 2015-12-30 Glucagon derivatives
ARP150104341A AR103323A1 (es) 2014-12-30 2015-12-30 Derivados de glucagón
HK18105858.0A HK1246323B (en) 2014-12-30 2015-12-30 Glucagon derivatives
NZ771617A NZ771617B2 (en) 2015-12-30 Glucagon derivatives
US15/539,238 US10513550B2 (en) 2014-12-30 2015-12-30 Glucagon derivatives
TW104144429A TWI696631B (zh) 2014-12-30 2015-12-30 升糖素衍生物
NZ733649A NZ733649B2 (en) 2015-12-30 Glucagon derivatives
MX2017008715A MX389593B (es) 2014-12-30 2015-12-30 Derivados de glucagon.
SG10201906912VA SG10201906912VA (en) 2014-12-30 2015-12-30 Glucagon derivatives
CA2972001A CA2972001C (en) 2014-12-30 2015-12-30 GLUCAGON DERIVATIVES
EA201791498A EA036479B1 (ru) 2014-12-30 2015-12-30 Пептид, активирующий рецептор гпп-1 и рецептор глюкагона, фармацевтическая композиция на его основе и их применение для профилактики или лечения ожирения
EP15875711.2A EP3240802B1 (en) 2014-12-30 2015-12-30 Glucagon derivatives
BR112017013845A BR112017013845A2 (pt) 2014-12-30 2015-12-30 derivados de glucagon
PCT/KR2015/014481 WO2016108617A1 (en) 2014-12-30 2015-12-30 Glucagon derivatives
JP2017534915A JP6758297B2 (ja) 2014-12-30 2015-12-30 グルカゴン誘導体
CN201580071897.XA CN107250155B (zh) 2014-12-30 2015-12-30 胰高血糖素衍生物
UAA201707894A UA122967C2 (uk) 2014-12-30 2015-12-30 Похідна глюкагону
IL253001A IL253001B (en) 2014-12-30 2017-06-19 History of glucagon
ZA2017/04328A ZA201704328B (en) 2014-12-30 2017-06-26 Glucagon derivatives
PH12017501205A PH12017501205A1 (en) 2014-12-30 2017-06-27 Glucagon derivatives
US16/684,110 US11254724B2 (en) 2014-12-30 2019-11-14 Glucagon derivatives
US17/499,222 US12018060B2 (en) 2014-12-30 2021-10-12 Glucagon derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020140193691A KR102418477B1 (ko) 2014-12-30 2014-12-30 글루카곤 유도체

Publications (2)

Publication Number Publication Date
KR20160082026A KR20160082026A (ko) 2016-07-08
KR102418477B1 true KR102418477B1 (ko) 2022-07-08

Family

ID=56284668

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020140193691A Active KR102418477B1 (ko) 2014-12-30 2014-12-30 글루카곤 유도체

Country Status (18)

Country Link
US (3) US10513550B2 (enExample)
EP (1) EP3240802B1 (enExample)
JP (1) JP6758297B2 (enExample)
KR (1) KR102418477B1 (enExample)
CN (1) CN107250155B (enExample)
AR (1) AR103323A1 (enExample)
AU (1) AU2015372767B2 (enExample)
BR (1) BR112017013845A2 (enExample)
CA (1) CA2972001C (enExample)
EA (1) EA036479B1 (enExample)
IL (1) IL253001B (enExample)
MX (1) MX389593B (enExample)
PH (1) PH12017501205A1 (enExample)
SG (2) SG10201906912VA (enExample)
TW (1) TWI696631B (enExample)
UA (1) UA122967C2 (enExample)
WO (1) WO2016108617A1 (enExample)
ZA (1) ZA201704328B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
SG11201805586SA (en) 2015-12-31 2018-07-30 Hanmi Pharmaceutical Co Ltd Triple glucagon/glp-1/gip receptor agonist
CN121591873A (zh) * 2018-07-19 2026-03-03 D&D制药技术股份有限公司 包括多肽的药物组合物
JP2025526148A (ja) 2022-08-18 2025-08-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 長時間作用型ｇｌｐ－１／グルカゴン受容体アゴニスト及びｎｐｙ２受容体アゴニストを含む組合せ治療

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