KR102418477B1 - 글루카곤 유도체 - Google Patents
글루카곤 유도체 Download PDFInfo
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- KR102418477B1 KR102418477B1 KR1020140193691A KR20140193691A KR102418477B1 KR 102418477 B1 KR102418477 B1 KR 102418477B1 KR 1020140193691 A KR1020140193691 A KR 1020140193691A KR 20140193691 A KR20140193691 A KR 20140193691A KR 102418477 B1 KR102418477 B1 KR 102418477B1
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- KR
- South Korea
- Prior art keywords
- peptide
- glucagon
- receptor
- obesity
- present
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (24)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020140193691A KR102418477B1 (ko) | 2014-12-30 | 2014-12-30 | 글루카곤 유도체 |
| HK18105858.0A HK1246323B (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| EP15875711.2A EP3240802B1 (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| BR112017013845A BR112017013845A2 (pt) | 2014-12-30 | 2015-12-30 | derivados de glucagon |
| EA201791498A EA036479B1 (ru) | 2014-12-30 | 2015-12-30 | Пептид, активирующий рецептор гпп-1 и рецептор глюкагона, фармацевтическая композиция на его основе и их применение для профилактики или лечения ожирения |
| US15/539,238 US10513550B2 (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| NZ771617A NZ771617B2 (en) | 2015-12-30 | Glucagon derivatives | |
| PCT/KR2015/014481 WO2016108617A1 (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| TW104144429A TWI696631B (zh) | 2014-12-30 | 2015-12-30 | 升糖素衍生物 |
| MX2017008715A MX389593B (es) | 2014-12-30 | 2015-12-30 | Derivados de glucagon. |
| NZ733649A NZ733649B2 (en) | 2015-12-30 | Glucagon derivatives | |
| SG10201906912VA SG10201906912VA (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| AU2015372767A AU2015372767B2 (en) | 2014-12-30 | 2015-12-30 | Glucagon derivatives |
| CN201580071897.XA CN107250155B (zh) | 2014-12-30 | 2015-12-30 | 胰高血糖素衍生物 |
| UAA201707894A UA122967C2 (uk) | 2014-12-30 | 2015-12-30 | Похідна глюкагону |
| JP2017534915A JP6758297B2 (ja) | 2014-12-30 | 2015-12-30 | グルカゴン誘導体 |
| ARP150104341A AR103323A1 (es) | 2014-12-30 | 2015-12-30 | Derivados de glucagón |
| CA2972001A CA2972001C (en) | 2014-12-30 | 2015-12-30 | GLUCAGON DERIVATIVES |
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| TN2017000271A1 (en) * | 2014-12-30 | 2018-10-19 | Hanmi Pharm Ind Co Ltd | Glucagon derivative having improved stability |
| TN2017000555A1 (en) | 2015-06-30 | 2019-04-12 | Hanmi Pharm Ind Co Ltd | Glucagon derivative and a composition comprising a long acting conjugate of the same |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
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| US20240091318A1 (en) | 2022-08-18 | 2024-03-21 | Boehringer Ingelheim International Gmbh | Combination therapy comprising long acting glp-1/glucagon and npy2 receptor agonists |
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