JP2017538785A5 - - Google Patents
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- JP2017538785A5 JP2017538785A5 JP2017548361A JP2017548361A JP2017538785A5 JP 2017538785 A5 JP2017538785 A5 JP 2017538785A5 JP 2017548361 A JP2017548361 A JP 2017548361A JP 2017548361 A JP2017548361 A JP 2017548361A JP 2017538785 A5 JP2017538785 A5 JP 2017538785A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- independently
- ring
- halogen atom
- haloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 125000001424 substituent group Chemical group 0.000 claims description 42
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 30
- 238000000034 method Methods 0.000 claims description 24
- 150000001875 compounds Chemical class 0.000 claims description 15
- 125000004433 nitrogen atom Chemical group N* 0.000 claims description 6
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 claims description 3
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 125000004076 pyridyl group Chemical group 0.000 claims description 3
- 125000000623 heterocyclic group Chemical group 0.000 claims description 2
- 125000005843 halogen group Chemical group 0.000 claims 25
- 125000006583 (C1-C3) haloalkyl group Chemical group 0.000 claims 19
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 claims 9
- 125000004093 cyano group Chemical group *C#N 0.000 claims 7
- 125000001188 haloalkyl group Chemical group 0.000 claims 7
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 claims 6
- 125000004122 cyclic group Chemical group 0.000 claims 6
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 6
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 6
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical group [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims 5
- 125000003545 alkoxy group Chemical group 0.000 claims 4
- 125000005347 halocycloalkyl group Chemical group 0.000 claims 4
- 125000004434 sulfur atom Chemical group 0.000 claims 4
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical group CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 claims 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 3
- 125000005119 alkyl cycloalkyl group Chemical group 0.000 claims 3
- 150000001721 carbon Chemical group 0.000 claims 3
- 125000000392 cycloalkenyl group Chemical group 0.000 claims 3
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 3
- 125000004665 trialkylsilyl group Chemical group 0.000 claims 3
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 2
- 125000006781 (C4-C10) cycloalkylcarbonyl group Chemical group 0.000 claims 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000002837 carbocyclic group Chemical group 0.000 claims 2
- 239000003054 catalyst Substances 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000004438 haloalkoxy group Chemical group 0.000 claims 2
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 claims 2
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 claims 2
- 125000005842 heteroatom Chemical group 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 229910052759 nickel Inorganic materials 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 125000004845 (C1-C6) alkylsulfonylamino group Chemical group 0.000 claims 1
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 claims 1
- 125000006815 (C4-C10) cycloalkylaminocarbonyl group Chemical group 0.000 claims 1
- FQHVMLOWACVQFN-UHFFFAOYSA-N 1-(1,2,3,4-tetrahydroisoquinolin-1-yl)-3,4-dihydroisoquinoline-1,2-diamine Chemical compound C1(N(CCC2=CC=CC=C12)N)(C1NCCC2=CC=CC=C12)N FQHVMLOWACVQFN-UHFFFAOYSA-N 0.000 claims 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 claims 1
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 claims 1
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 claims 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical group C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 1
- -1 N-substituted cyclohexane-1,2-diamine Chemical class 0.000 claims 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003302 alkenyloxy group Chemical group 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 claims 1
- 125000005081 alkoxyalkoxyalkyl group Chemical group 0.000 claims 1
- 125000004466 alkoxycarbonylamino group Chemical group 0.000 claims 1
- 125000000278 alkyl amino alkyl group Chemical group 0.000 claims 1
- 125000004457 alkyl amino carbonyl group Chemical group 0.000 claims 1
- 125000003806 alkyl carbonyl amino group Chemical group 0.000 claims 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 claims 1
- 125000004687 alkyl sulfinyl alkyl group Chemical group 0.000 claims 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 claims 1
- 125000004688 alkyl sulfonyl alkyl group Chemical group 0.000 claims 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 claims 1
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 claims 1
- 125000006350 alkyl thio alkyl group Chemical group 0.000 claims 1
- 125000004414 alkyl thio group Chemical group 0.000 claims 1
- 125000005133 alkynyloxy group Chemical group 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 1
- 125000006310 cycloalkyl amino group Chemical group 0.000 claims 1
- 125000005357 cycloalkylalkynyl group Chemical group 0.000 claims 1
- 125000005144 cycloalkylsulfonyl group Chemical group 0.000 claims 1
- 125000005366 cycloalkylthio group Chemical group 0.000 claims 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 claims 1
- 125000004473 dialkylaminocarbonyl group Chemical group 0.000 claims 1
- 125000004427 diamine group Chemical group 0.000 claims 1
- 125000004994 halo alkoxy alkyl group Chemical group 0.000 claims 1
- 125000005221 halo alkyl carbonyl amino group Chemical group 0.000 claims 1
- 125000000262 haloalkenyl group Chemical group 0.000 claims 1
- 125000005291 haloalkenyloxy group Chemical group 0.000 claims 1
- 125000004993 haloalkoxycarbonyl group Chemical group 0.000 claims 1
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 claims 1
- 125000004995 haloalkylthio group Chemical group 0.000 claims 1
- 125000000232 haloalkynyl group Chemical group 0.000 claims 1
- 125000005292 haloalkynyloxy group Chemical group 0.000 claims 1
- 125000004971 nitroalkyl group Chemical group 0.000 claims 1
- 150000007530 organic bases Chemical class 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 1
- 0 C*(C(C(C(CCC=[N+][O-])OC*)C(ON)=O)=O)[N+](C)[O-] Chemical compound C*(C(C(C(CCC=[N+][O-])OC*)C(ON)=O)=O)[N+](C)[O-] 0.000 description 2
- 125000002541 furyl group Chemical group 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088971P | 2014-12-08 | 2014-12-08 | |
| US62/088,971 | 2014-12-08 | ||
| PCT/US2015/063101 WO2016094117A1 (en) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017538785A JP2017538785A (ja) | 2017-12-28 |
| JP2017538785A5 true JP2017538785A5 (enExample) | 2019-01-17 |
| JP6611816B2 JP6611816B2 (ja) | 2019-11-27 |
Family
ID=54782892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017548361A Active JP6611816B2 (ja) | 2014-12-08 | 2015-12-01 | ３−オキソ−３−（アリールアミノ）プロパノエイト、その製造方法、およびピロリジノンの製造におけるその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10227286B2 (enExample) |
| EP (1) | EP3230264B1 (enExample) |
| JP (1) | JP6611816B2 (enExample) |
| KR (1) | KR102542215B1 (enExample) |
| CN (1) | CN107001260B (enExample) |
| AR (1) | AR102939A1 (enExample) |
| AU (1) | AU2015361018B2 (enExample) |
| BR (1) | BR112017009701B1 (enExample) |
| ES (1) | ES2759267T3 (enExample) |
| HU (1) | HUE047582T2 (enExample) |
| IL (1) | IL252637A (enExample) |
| MX (1) | MX382656B (enExample) |
| PL (1) | PL3230264T3 (enExample) |
| RU (1) | RU2712831C2 (enExample) |
| SG (1) | SG11201702924WA (enExample) |
| TW (1) | TWI694982B (enExample) |
| WO (1) | WO2016094117A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| JP6524086B2 (ja) | 2013-12-03 | 2019-06-05 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | ピロリジノン除草剤 |
| EP3164386B1 (en) | 2014-07-02 | 2020-10-07 | FMC Corporation | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
| PL3294743T3 (pl) | 2015-05-12 | 2020-03-31 | Fmc Corporation | Podstawione arylem związki bicykliczne jako środki chwastobójcze |
| EP3303287B1 (en) | 2015-05-29 | 2020-12-16 | FMC Corporation | Substituted cyclic amides as herbicides |
| US10654804B2 (en) | 2015-06-02 | 2020-05-19 | Fmc Corporation | Substituted cyclic amides and their use as herbicides |
| AU2016303209B2 (en) | 2015-07-31 | 2021-04-01 | Fmc Corporation | Cyclic N-carboxamide compounds useful as herbicides |
| GB201617050D0 (en) | 2016-10-07 | 2016-11-23 | Syngenta Participations Ag | Herbicidal mixtures |
| EP3558962B1 (en) | 2016-12-21 | 2023-07-12 | FMC Corporation | Nitrone herbicides |
| SG11201908640TA (en) | 2017-03-21 | 2019-10-30 | Fmc Corp | Pyrrolidinones and a process to prepare them |
| BR112019019551A2 (pt) | 2017-03-21 | 2020-04-22 | Fmc Corp | mistura, e, método para controlar o crescimento de vegetação indesejada |
| WO2018177836A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | N-cyclopropyl-2-oxopyrrolidin-3-carboxamid-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| WO2018177837A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | 4-cyclopentyl- und 4-cyclopropyl-2-oxopyrrolidin-3-carboxami d-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| WO2019025156A1 (de) | 2017-08-03 | 2019-02-07 | Bayer Aktiengesellschaft | Substituierte pyrrolidinone sowie deren salze und ihre verwendung als herbizide wirkstoffe |
| GB201819747D0 (en) | 2018-12-04 | 2019-01-16 | Syngenta Participations Ag | Herbicidal compositions |
| CN113423272A (zh) | 2019-02-15 | 2021-09-21 | 先正达农作物保护股份公司 | 除草组合物 |
| IL313538A (en) | 2021-12-15 | 2024-08-01 | Adama Agan Ltd | Useful compounds for the preparation of various agrochemicals and their markers |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1262277B (de) | 1962-12-05 | 1968-03-07 | Basf Ag | Verfahren zur Herstellung von Pyrrolidonen |
| US3741989A (en) | 1970-10-27 | 1973-06-26 | Abbott Lab | Lactonic acetals |
| JPS5356288A (en) | 1976-10-30 | 1978-05-22 | Matsushita Electric Works Ltd | Preparation of phenolic resin |
| JPS5488114A (en) | 1977-12-26 | 1979-07-13 | Fuji Photo Film Co Ltd | Manufacturing device for photograph seal |
| US4594094A (en) | 1983-04-04 | 1986-06-10 | Shell Oil Company | Oxacycloalkane-alpha-(thio)carboxylic acid derivatives and use as plant growth regulators and herbicides |
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| JP3487669B2 (ja) | 1995-03-28 | 2004-01-19 | 積水化学工業株式会社 | 不飽和ポリエステル樹脂組成物 |
| WO2000009481A1 (en) | 1998-08-11 | 2000-02-24 | Takeda Chemical Industries, Ltd. | Cyclic amide compounds, process for producing the same, intermediates thereof and herbicides |
| CA2461961A1 (en) | 2001-10-08 | 2003-04-17 | Ucb, S.A. | Use of 2-oxo-1-pyrrolidine derivatives for the treatment of dyskinesia and movement disorders |
| US7250443B2 (en) | 2002-08-23 | 2007-07-31 | Chiron Corporation | Pyrrole based inhibitors of glycogen synthase kinase 3 |
| CA2502478A1 (en) | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidine-2-one-3-carboxamides |
| WO2004046081A1 (en) | 2002-11-15 | 2004-06-03 | Dna Link, Inc. | Beta-nitrostyrene compound and telomerase inhibitor having an anticancer activity |
| US7205318B2 (en) | 2003-03-18 | 2007-04-17 | Bristol-Myers Squibb Company | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors |
| BRPI0607294A2 (pt) | 2005-01-28 | 2009-08-25 | Irm Llc | processos para sìntese de aril pirrolidonas, bem como mistura |
| US20070123508A1 (en) | 2005-05-27 | 2007-05-31 | Roger Olsson | PAR2-modulating compounds and their use |
| WO2007066828A1 (ja) | 2005-12-09 | 2007-06-14 | Sumitomo Chemical Company, Limited | 光学活性な４－アミノ－３－置換フェニルブタン酸の製造方法 |
| ES2304220B1 (es) | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| EP2065380A1 (en) | 2007-08-22 | 2009-06-03 | F.Hoffmann-La Roche Ag | Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer |
| CN101412711A (zh) | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | 氨基甲酸酯类衍生物及其在医药上的应用 |
| CN102137841B (zh) | 2008-09-02 | 2014-05-14 | 日产化学工业株式会社 | 邻位取代卤代烷基磺酰苯胺衍生物及除草剂 |
| EP2363390A4 (en) | 2008-11-04 | 2012-06-13 | Teijin Pharma Ltd | DERIVATIVE LACTAM OF VITAMIN D3 |
| KR20110117194A (ko) * | 2009-02-23 | 2011-10-26 | 에프. 호프만-라 로슈 아게 | 암 치료를 위한 신규한 오르토-아미노아미드 |
| CN101747252A (zh) * | 2009-12-28 | 2010-06-23 | 嘉兴宜博生物医药科技有限公司 | R构诺普利兰的合成方法 |
| JP5788496B2 (ja) | 2010-08-10 | 2015-09-30 | 武田薬品工業株式会社 | 複素環化合物およびその用途 |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| HRP20161786T1 (hr) | 2011-05-13 | 2017-03-10 | Array Biopharma, Inc. | Pirolidinil urea, pirolidinil tiourea i pirolidinil gvanidin spojevi kao inhibitori trka kinaze |
| CN102531918B (zh) | 2012-01-18 | 2013-10-02 | 安阳工学院 | 一种对映纯对称反式二烷基环己胺的合成方法 |
| KR20130142477A (ko) | 2012-06-19 | 2013-12-30 | 순천향대학교 산학협력단 | 키랄 나이트로사이클로프로판 유도체의 제조방법 |
| US20160137639A1 (en) | 2012-10-26 | 2016-05-19 | Japan Tobacco Inc. | Triazole-isoxazole compound and medical use thereof |
| JP6524086B2 (ja) * | 2013-12-03 | 2019-06-05 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | ピロリジノン除草剤 |
| GB201321743D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| RU2555370C1 (ru) | 2014-02-12 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный технический университет" | Способ энантиоселективного синтеза диэтил[3-метил-(1s)-(нитрометил)бутил]малоната формулы i |
| EP3164386B1 (en) | 2014-07-02 | 2020-10-07 | FMC Corporation | Piperidinone herbicides |
| EP3280709B1 (en) | 2015-04-10 | 2021-05-26 | FMC Corporation | Substituted cyclic amides as herbicides |
| CN107531658B (zh) | 2015-04-27 | 2021-07-27 | Fmc公司 | 作为除草剂的丁内酯 |
| PL3294743T3 (pl) | 2015-05-12 | 2020-03-31 | Fmc Corporation | Podstawione arylem związki bicykliczne jako środki chwastobójcze |
| EP3303287B1 (en) | 2015-05-29 | 2020-12-16 | FMC Corporation | Substituted cyclic amides as herbicides |
| US10654804B2 (en) | 2015-06-02 | 2020-05-19 | Fmc Corporation | Substituted cyclic amides and their use as herbicides |
| AU2016303209B2 (en) | 2015-07-31 | 2021-04-01 | Fmc Corporation | Cyclic N-carboxamide compounds useful as herbicides |
| EP3558962B1 (en) | 2016-12-21 | 2023-07-12 | FMC Corporation | Nitrone herbicides |
| BR112019019551A2 (pt) | 2017-03-21 | 2020-04-22 | Fmc Corp | mistura, e, método para controlar o crescimento de vegetação indesejada |
| SG11201908640TA (en) | 2017-03-21 | 2019-10-30 | Fmc Corp | Pyrrolidinones and a process to prepare them |
-
2015
- 2015-12-01 EP EP15805092.2A patent/EP3230264B1/en active Active
- 2015-12-01 AU AU2015361018A patent/AU2015361018B2/en active Active
- 2015-12-01 HU HUE15805092A patent/HUE047582T2/hu unknown
- 2015-12-01 BR BR112017009701-0A patent/BR112017009701B1/pt active IP Right Grant
- 2015-12-01 CN CN201580065080.1A patent/CN107001260B/zh active Active
- 2015-12-01 SG SG11201702924WA patent/SG11201702924WA/en unknown
- 2015-12-01 RU RU2017123114A patent/RU2712831C2/ru active
- 2015-12-01 JP JP2017548361A patent/JP6611816B2/ja active Active
- 2015-12-01 MX MX2017007087A patent/MX382656B/es unknown
- 2015-12-01 PL PL15805092T patent/PL3230264T3/pl unknown
- 2015-12-01 US US15/533,448 patent/US10227286B2/en active Active
- 2015-12-01 WO PCT/US2015/063101 patent/WO2016094117A1/en not_active Ceased
- 2015-12-01 KR KR1020177018406A patent/KR102542215B1/ko active Active
- 2015-12-01 ES ES15805092T patent/ES2759267T3/es active Active
- 2015-12-04 TW TW104140692A patent/TWI694982B/zh active
- 2015-12-04 AR ARP150103996A patent/AR102939A1/es active IP Right Grant
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2017
- 2017-06-04 IL IL252637A patent/IL252637A/en active IP Right Grant