AU2015361018B2 - 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones - Google Patents
3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones Download PDFInfo
- Publication number
- AU2015361018B2 AU2015361018B2 AU2015361018A AU2015361018A AU2015361018B2 AU 2015361018 B2 AU2015361018 B2 AU 2015361018B2 AU 2015361018 A AU2015361018 A AU 2015361018A AU 2015361018 A AU2015361018 A AU 2015361018A AU 2015361018 B2 AU2015361018 B2 AU 2015361018B2
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- HTMGQIXFZMZZKD-UHFFFAOYSA-N C(CC1)Cc2c1cncc2 Chemical compound C(CC1)Cc2c1cncc2 HTMGQIXFZMZZKD-UHFFFAOYSA-N 0.000 description 1
- YQDGQEKUTLYWJU-UHFFFAOYSA-N C1Cc2cccnc2CC1 Chemical compound C1Cc2cccnc2CC1 YQDGQEKUTLYWJU-UHFFFAOYSA-N 0.000 description 1
- BNBQRQQYDMDJAH-UHFFFAOYSA-N C1Oc(cccc2)c2OC1 Chemical compound C1Oc(cccc2)c2OC1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 description 1
- HCVRYRKQGOZDDA-UHFFFAOYSA-N C=CC1=C(C=C)OCOC1 Chemical compound C=CC1=C(C=C)OCOC1 HCVRYRKQGOZDDA-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B31/00—Reduction in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462088971P | 2014-12-08 | 2014-12-08 | |
| US62/088,971 | 2014-12-08 | ||
| PCT/US2015/063101 WO2016094117A1 (en) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2015361018A1 AU2015361018A1 (en) | 2017-04-27 |
| AU2015361018B2 true AU2015361018B2 (en) | 2020-01-16 |
Family
ID=54782892
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015361018A Active AU2015361018B2 (en) | 2014-12-08 | 2015-12-01 | 3-oxo-3-(arylamino)propanoates, a process for their preparation, and their use in preparing pyrrolidinones |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10227286B2 (enExample) |
| EP (1) | EP3230264B1 (enExample) |
| JP (1) | JP6611816B2 (enExample) |
| KR (1) | KR102542215B1 (enExample) |
| CN (1) | CN107001260B (enExample) |
| AR (1) | AR102939A1 (enExample) |
| AU (1) | AU2015361018B2 (enExample) |
| BR (1) | BR112017009701B1 (enExample) |
| ES (1) | ES2759267T3 (enExample) |
| HU (1) | HUE047582T2 (enExample) |
| IL (1) | IL252637A (enExample) |
| MX (1) | MX382656B (enExample) |
| PL (1) | PL3230264T3 (enExample) |
| RU (1) | RU2712831C2 (enExample) |
| SG (1) | SG11201702924WA (enExample) |
| TW (1) | TWI694982B (enExample) |
| WO (1) | WO2016094117A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11589583B2 (en) | 2013-12-03 | 2023-02-28 | Fmc Corporation | Pyrrolidinones herbicides |
| ES2923506T3 (es) | 2013-12-03 | 2022-09-28 | Fmc Corp | Herbicidas de pirrolidinona |
| PE20170444A1 (es) | 2014-07-02 | 2017-05-11 | Du Pont | Herbicidas de piperidinona |
| US10405547B2 (en) | 2015-04-10 | 2019-09-10 | Fmc Corporation | Substituted cyclic amides as herbicides |
| BR112017020094B1 (pt) | 2015-04-27 | 2022-01-11 | Fmc Corporation | Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada |
| WO2016182780A1 (en) | 2015-05-12 | 2016-11-17 | E I Du Pont De Nemours And Company | Aryl substituted bicyclic compounds as herbicides |
| CA2983590C (en) | 2015-05-29 | 2021-11-30 | E I Du Pont De Nemours And Company | Substituted cyclic amides as herbicides |
| EP3303321A1 (en) * | 2015-06-02 | 2018-04-11 | E. I. du Pont de Nemours and Company | Substituted cyclic amides and their use as herbicides |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤として有用な環状ｎ−カルボキサミド化合物 |
| GB201617050D0 (en) | 2016-10-07 | 2016-11-23 | Syngenta Participations Ag | Herbicidal mixtures |
| US11498899B2 (en) | 2016-12-21 | 2022-11-15 | Fmc Corporation | Nitrone herbicides |
| JP7548697B2 (ja) | 2017-03-21 | 2024-09-10 | エフ エム シー コーポレーション | 除草剤混合物、組成物、及び方法 |
| CN110691516B (zh) | 2017-03-21 | 2022-10-28 | Fmc公司 | 吡咯烷酮及其制备方法 |
| WO2018177837A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | 4-cyclopentyl- und 4-cyclopropyl-2-oxopyrrolidin-3-carboxami d-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| WO2018177836A1 (de) | 2017-03-30 | 2018-10-04 | Bayer Aktiengesellschaft | N-cyclopropyl-2-oxopyrrolidin-3-carboxamid-derivate und verwandte verbindungen als herbizide pflanzenschutzmittel |
| AR111839A1 (es) | 2017-05-30 | 2019-08-21 | Fmc Corp | Lactamas 3-sustituidas herbicidas |
| AR111967A1 (es) | 2017-05-30 | 2019-09-04 | Fmc Corp | Amidas herbicidas |
| WO2019025156A1 (de) | 2017-08-03 | 2019-02-07 | Bayer Aktiengesellschaft | Substituierte pyrrolidinone sowie deren salze und ihre verwendung als herbizide wirkstoffe |
| GB201819747D0 (en) | 2018-12-04 | 2019-01-16 | Syngenta Participations Ag | Herbicidal compositions |
| CN113423272A (zh) | 2019-02-15 | 2021-09-21 | 先正达农作物保护股份公司 | 除草组合物 |
| AR127968A1 (es) | 2021-12-15 | 2024-03-13 | Adama Agan Ltd | Compuestos útiles para la preparación de varios agroquímicos y sus marcadores |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| WO2004037787A1 (de) * | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidin-2-on-3-carboxamide |
| WO2014065413A1 (ja) * | 2012-10-26 | 2014-05-01 | 日本たばこ産業株式会社 | トリアゾール・イソオキサゾール化合物およびその医薬用途 |
| WO2015084796A1 (en) * | 2013-12-03 | 2015-06-11 | E. I. Du Pont De Nemours And Company | Pyrrolidinones as herbicides |
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| DE1262277B (de) | 1962-12-05 | 1968-03-07 | Basf Ag | Verfahren zur Herstellung von Pyrrolidonen |
| US3741989A (en) | 1970-10-27 | 1973-06-26 | Abbott Lab | Lactonic acetals |
| JPS5356288A (en) | 1976-10-30 | 1978-05-22 | Matsushita Electric Works Ltd | Preparation of phenolic resin |
| JPS5488114A (en) | 1977-12-26 | 1979-07-13 | Fuji Photo Film Co Ltd | Manufacturing device for photograph seal |
| US4594094A (en) | 1983-04-04 | 1986-06-10 | Shell Oil Company | Oxacycloalkane-alpha-(thio)carboxylic acid derivatives and use as plant growth regulators and herbicides |
| JP3487669B2 (ja) | 1995-03-28 | 2004-01-19 | 積水化学工業株式会社 | 不飽和ポリエステル樹脂組成物 |
| WO2000009481A1 (en) | 1998-08-11 | 2000-02-24 | Takeda Chemical Industries, Ltd. | Cyclic amide compounds, process for producing the same, intermediates thereof and herbicides |
| ATE353645T1 (de) | 2001-10-08 | 2007-03-15 | Ucb Sa | Verwendung von 2-oxo-1-pyrrolidin-derivaten zur herstellung eines arzneimittels zur behandlung von dyskinesia |
| US7250443B2 (en) | 2002-08-23 | 2007-07-31 | Chiron Corporation | Pyrrole based inhibitors of glycogen synthase kinase 3 |
| KR100614422B1 (ko) | 2002-11-15 | 2006-08-21 | 주식회사디엔에이링크 | 베타-니트로스티렌계 화합물 및 이를 함유하는 항암 조성물 |
| US7205318B2 (en) | 2003-03-18 | 2007-04-17 | Bristol-Myers Squibb Company | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors |
| AU2006209241B2 (en) | 2005-01-28 | 2009-10-22 | Irm Llc | Synthesis of aryl pyrrolidones |
| US20070123508A1 (en) | 2005-05-27 | 2007-05-31 | Roger Olsson | PAR2-modulating compounds and their use |
| WO2007066828A1 (ja) | 2005-12-09 | 2007-06-14 | Sumitomo Chemical Company, Limited | 光学活性な４－アミノ－３－置換フェニルブタン酸の製造方法 |
| ES2304220B1 (es) | 2007-03-02 | 2009-09-11 | Universidad De Zaragoza | Composicion para el tratamiento de enfermedades infecciosas. |
| EP2065380A1 (en) | 2007-08-22 | 2009-06-03 | F.Hoffmann-La Roche Ag | Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer |
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| WO2010026989A1 (ja) | 2008-09-02 | 2010-03-11 | 日産化学工業株式会社 | オルト置換ハロアルキルスルホンアニリド誘導体及び除草剤 |
| WO2010053165A1 (ja) | 2008-11-04 | 2010-05-14 | 帝人ファーマ株式会社 | ビタミンｄ３ラクタム誘導体 |
| BRPI1007995A2 (pt) * | 2009-02-23 | 2019-09-24 | Hoffmann La Roche | orto-aminoamidas para o tratamento de cãncer. |
| CN101747252A (zh) * | 2009-12-28 | 2010-06-23 | 嘉兴宜博生物医药科技有限公司 | R构诺普利兰的合成方法 |
| PT2603513T (pt) | 2010-08-10 | 2020-06-08 | Takeda Pharmaceuticals Co | Composto heterocíclico e sua utilização como modulador alostérico positivo do recetor de ampa |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| RU2606131C2 (ru) | 2011-05-13 | 2017-01-10 | Эррэй Биофарма Инк. | СОЕДИНЕНИЯ ПИРРОЛИДИНИЛМОЧЕВИНЫ И ПИРРОЛИДИНИЛТИОМОЧЕВИНЫ КАК ИНГИБИТОРЫ КИНАЗЫ TrkA |
| CN102531918B (zh) | 2012-01-18 | 2013-10-02 | 安阳工学院 | 一种对映纯对称反式二烷基环己胺的合成方法 |
| KR20130142477A (ko) | 2012-06-19 | 2013-12-30 | 순천향대학교 산학협력단 | 키랄 나이트로사이클로프로판 유도체의 제조방법 |
| GB201321743D0 (en) | 2013-12-09 | 2014-01-22 | Ucb Pharma Sa | Therapeutic agents |
| RU2555370C1 (ru) | 2014-02-12 | 2015-07-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Самарский государственный технический университет" | Способ энантиоселективного синтеза диэтил[3-метил-(1s)-(нитрометил)бутил]малоната формулы i |
| PE20170444A1 (es) | 2014-07-02 | 2017-05-11 | Du Pont | Herbicidas de piperidinona |
| US10405547B2 (en) | 2015-04-10 | 2019-09-10 | Fmc Corporation | Substituted cyclic amides as herbicides |
| BR112017020094B1 (pt) | 2015-04-27 | 2022-01-11 | Fmc Corporation | Composto, composições herbicidas, mistura de herbicida e método para controlar o crescimento de vegetação indesejada |
| WO2016182780A1 (en) | 2015-05-12 | 2016-11-17 | E I Du Pont De Nemours And Company | Aryl substituted bicyclic compounds as herbicides |
| CA2983590C (en) | 2015-05-29 | 2021-11-30 | E I Du Pont De Nemours And Company | Substituted cyclic amides as herbicides |
| EP3303321A1 (en) * | 2015-06-02 | 2018-04-11 | E. I. du Pont de Nemours and Company | Substituted cyclic amides and their use as herbicides |
| JP6937290B2 (ja) | 2015-07-31 | 2021-09-22 | エフ エム シー コーポレーションＦｍｃ Ｃｏｒｐｏｒａｔｉｏｎ | 除草剤として有用な環状ｎ−カルボキサミド化合物 |
| US11498899B2 (en) | 2016-12-21 | 2022-11-15 | Fmc Corporation | Nitrone herbicides |
| CN110691516B (zh) | 2017-03-21 | 2022-10-28 | Fmc公司 | 吡咯烷酮及其制备方法 |
| JP7548697B2 (ja) | 2017-03-21 | 2024-09-10 | エフ エム シー コーポレーション | 除草剤混合物、組成物、及び方法 |
-
2015
- 2015-12-01 HU HUE15805092A patent/HUE047582T2/hu unknown
- 2015-12-01 SG SG11201702924WA patent/SG11201702924WA/en unknown
- 2015-12-01 AU AU2015361018A patent/AU2015361018B2/en active Active
- 2015-12-01 PL PL15805092T patent/PL3230264T3/pl unknown
- 2015-12-01 CN CN201580065080.1A patent/CN107001260B/zh active Active
- 2015-12-01 EP EP15805092.2A patent/EP3230264B1/en active Active
- 2015-12-01 WO PCT/US2015/063101 patent/WO2016094117A1/en not_active Ceased
- 2015-12-01 KR KR1020177018406A patent/KR102542215B1/ko active Active
- 2015-12-01 MX MX2017007087A patent/MX382656B/es unknown
- 2015-12-01 JP JP2017548361A patent/JP6611816B2/ja active Active
- 2015-12-01 RU RU2017123114A patent/RU2712831C2/ru active
- 2015-12-01 US US15/533,448 patent/US10227286B2/en active Active
- 2015-12-01 ES ES15805092T patent/ES2759267T3/es active Active
- 2015-12-01 BR BR112017009701-0A patent/BR112017009701B1/pt active IP Right Grant
- 2015-12-04 AR ARP150103996A patent/AR102939A1/es active IP Right Grant
- 2015-12-04 TW TW104140692A patent/TWI694982B/zh active
-
2017
- 2017-06-04 IL IL252637A patent/IL252637A/en active IP Right Grant
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4874422A (en) * | 1988-12-27 | 1989-10-17 | Ici Americas Inc. | 1-Phenyl-3-carboxyamidopyrrolidones and their use as herbicides |
| WO2004037787A1 (de) * | 2002-10-18 | 2004-05-06 | Basf Aktiengesellschaft | 1-phenylpyrrolidin-2-on-3-carboxamide |
| WO2014065413A1 (ja) * | 2012-10-26 | 2014-05-01 | 日本たばこ産業株式会社 | トリアゾール・イソオキサゾール化合物およびその医薬用途 |
| WO2015084796A1 (en) * | 2013-12-03 | 2015-06-11 | E. I. Du Pont De Nemours And Company | Pyrrolidinones as herbicides |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201702924WA (en) | 2017-05-30 |
| RU2017123114A (ru) | 2019-01-11 |
| BR112017009701B1 (pt) | 2021-09-08 |
| KR20170090491A (ko) | 2017-08-07 |
| MX2017007087A (es) | 2017-09-05 |
| HUE047582T2 (hu) | 2020-05-28 |
| EP3230264B1 (en) | 2019-09-11 |
| KR102542215B1 (ko) | 2023-06-12 |
| TW201632497A (zh) | 2016-09-16 |
| US10227286B2 (en) | 2019-03-12 |
| RU2712831C2 (ru) | 2020-02-03 |
| PL3230264T3 (pl) | 2020-03-31 |
| EP3230264A1 (en) | 2017-10-18 |
| US20180057442A1 (en) | 2018-03-01 |
| RU2017123114A3 (enExample) | 2019-07-17 |
| MX382656B (es) | 2025-03-13 |
| JP6611816B2 (ja) | 2019-11-27 |
| CN107001260A (zh) | 2017-08-01 |
| IL252637A (en) | 2017-11-30 |
| IL252637A0 (en) | 2017-07-31 |
| WO2016094117A1 (en) | 2016-06-16 |
| CN107001260B (zh) | 2020-11-10 |
| TWI694982B (zh) | 2020-06-01 |
| JP2017538785A (ja) | 2017-12-28 |
| BR112017009701A2 (pt) | 2018-02-20 |
| AU2015361018A1 (en) | 2017-04-27 |
| ES2759267T3 (es) | 2020-05-08 |
| AR102939A1 (es) | 2017-04-05 |
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