|
US2969364A
(en)
|
1957-12-26 |
1961-01-24 |
Upjohn Co |
Derivatives of 5-amino uracil
|
|
US3008491A
(en)
|
1959-05-04 |
1961-11-14 |
Chapman Valve Mfg Co |
Valve for concentric pipe lines
|
|
US3012976A
(en)
|
1959-11-02 |
1961-12-12 |
Miles Lab |
Specific test composition for occult blood
|
|
US3008281A
(en)
|
1960-07-14 |
1961-11-14 |
Nat Dairy Prod Corp |
Conveyor
|
|
US3299104A
(en)
|
1963-04-09 |
1967-01-17 |
Leo Ab |
Certain steroid nu-bis-(haloethyl)-carbamates
|
|
JPS59186924A
(ja)
|
1983-04-08 |
1984-10-23 |
Kureha Chem Ind Co Ltd |
ヒト免疫グロブリン結合抗腫瘍剤
|
|
US5093330A
(en)
|
1987-06-15 |
1992-03-03 |
Ciba-Geigy Corporation |
Staurosporine derivatives substituted at methylamino nitrogen
|
|
US5035878A
(en)
|
1988-09-12 |
1991-07-30 |
University Of Rochester |
Use of dithiocarbamates to counteract myelosuppression
|
|
US5542935A
(en)
|
1989-12-22 |
1996-08-06 |
Imarx Pharmaceutical Corp. |
Therapeutic delivery systems related applications
|
|
US5395855A
(en)
|
1990-05-07 |
1995-03-07 |
Ciba-Geigy Corporation |
Hydrazones
|
|
US5484612A
(en)
|
1993-09-22 |
1996-01-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
|
|
US6326469B1
(en)
|
1994-04-22 |
2001-12-04 |
Sugen, Inc. |
Megakaryocytic protein tyrosine kinases
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
PL188959B1
(pl)
|
1995-07-06 |
2005-05-31 |
Novartis Ag |
Pirolopirymidyny i sposoby ich wytwarzania
|
|
US6011069A
(en)
|
1995-12-26 |
2000-01-04 |
Nisshin Flour Milling Co., Ltd. |
Multidrug resistance inhibitors
|
|
US20020077461A1
(en)
|
1996-04-24 |
2002-06-20 |
Soren Bjorn |
Pharmaceutical formulation
|
|
DK0923941T3
(da)
|
1996-06-27 |
2006-09-18 |
Chugai Pharmaceutical Co Ltd |
Midler mod myelom der skal anvendes sammen med nitrogensennepantitumormidler
|
|
US6121245A
(en)
|
1997-01-29 |
2000-09-19 |
Firshein; Richard N. |
Method of treating cancer using alkylglycerols in conjunction with chemotherapy
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US20040072889A1
(en)
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
|
KR20010020611A
(ko)
|
1997-07-01 |
2001-03-15 |
아테로제닉스, 인코포레이티드 |
항산화제에 의한 과증식질병 치료의 향상
|
|
GB9721069D0
(en)
|
1997-10-03 |
1997-12-03 |
Pharmacia & Upjohn Spa |
Polymeric derivatives of camptothecin
|
|
CA2329130A1
(en)
|
1998-05-21 |
1999-11-25 |
Isis Pharmaceuticals Inc. |
Compositions and methods for non-parenteral delivery of oligonucleotides
|
|
WO1999063929A2
(en)
|
1998-06-08 |
1999-12-16 |
Advanced Medicine, Inc. |
Multibinding inhibitors of microsomal triglyceride transferase protein
|
|
KR20000011247A
(ko)
*
|
1998-07-23 |
2000-02-25 |
김윤 |
다당류를이용한대장선택성약물전달조성물및약학제제
|
|
ES2342240T3
(es)
|
1998-08-11 |
2010-07-02 |
Novartis Ag |
Derivados de isoquinolina con actividad que inhibe la angiogenia.
|
|
US6326390B1
(en)
|
1998-08-25 |
2001-12-04 |
King Pharmaceuticals Reseach And Development, Inc. |
Use of adenosine A3 receptor antagonists to inhibit tumor growth
|
|
ATE329596T1
(de)
|
1999-03-30 |
2006-07-15 |
Novartis Pharma Gmbh |
Phthalazinderivate zur behandlung von entzündlicher erkrankungen
|
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
|
US6635677B2
(en)
|
1999-08-13 |
2003-10-21 |
Case Western Reserve University |
Methoxyamine combinations in the treatment of cancer
|
|
US8791081B2
(en)
|
1999-08-13 |
2014-07-29 |
Case Western Reserve University |
MGMT inhibitor combination for the treatment of neoplastic disorders
|
|
US7811981B2
(en)
|
1999-08-30 |
2010-10-12 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Methods of and compositions for inhibiting the proliferation of mammalian cells
|
|
US20030072794A1
(en)
|
2000-06-09 |
2003-04-17 |
Teni Boulikas |
Encapsulation of plasmid DNA (lipogenes™) and therapeutic agents with nuclear localization signal/fusogenic peptide conjugates into targeted liposome complexes
|
|
CA2413313C
(en)
|
2000-06-23 |
2011-06-14 |
Mitsubishi Pharma Corporation |
Antitumor effect potentiators
|
|
PE20020354A1
(es)
|
2000-09-01 |
2002-06-12 |
Novartis Ag |
Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
|
|
AU2002227383B2
(en)
|
2000-10-30 |
2004-07-08 |
Euro-Celtique S.A. |
Controlled release hydrocodone formulations
|
|
ITMI20002358A1
(it)
|
2000-10-31 |
2002-05-01 |
Flavio Moroni |
Derivati di tieno ,2, 3-c|isochinolin-3-one come inibitori della poli(a dp-ribosio)polimerasi
|
|
US7619005B2
(en)
|
2000-11-01 |
2009-11-17 |
Cognition Pharmaceuticals Llc |
Methods for treating cognitive impairment in humans with Multiple Sclerosis
|
|
US20100098691A1
(en)
|
2001-01-24 |
2010-04-22 |
S'bio Pte Ltd |
Combination of benzimidazole anti-cancer agent and a second anti-cancer agent
|
|
TWI238824B
(en)
|
2001-05-14 |
2005-09-01 |
Novartis Ag |
4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
|
|
PT1397155E
(pt)
|
2001-06-21 |
2015-12-07 |
Genentech Inc |
Formulação de libertação sustentada
|
|
US20030158118A1
(en)
|
2001-11-26 |
2003-08-21 |
Weidner Morten Sloth |
Combination of cimetidine and cysteine derivatives for treating cancer
|
|
US7045534B2
(en)
|
2002-02-12 |
2006-05-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods of reducing angiogenesis
|
|
WO2003070823A2
(en)
|
2002-02-20 |
2003-08-28 |
The General Hospital Corporation |
Conjugates comprising a biodegradable polymer and uses therefor
|
|
US8580782B2
(en)
|
2002-09-04 |
2013-11-12 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors
|
|
ATE468855T1
(de)
*
|
2002-11-12 |
2010-06-15 |
Jewish General Hospital |
Kombination von stickstoff-senf analogen und imatinib für die behandlung von chronischer lymphatischer leukämie
|
|
KR20050090435A
(ko)
|
2002-12-30 |
2005-09-13 |
셀진 코포레이션 |
플루오로알콕시-치환된 1,3-디히드로-이소인돌릴 화합물 및그의 제약학적 용도
|
|
PT2476667E
(pt)
|
2003-02-26 |
2014-09-18 |
Sugen Inc |
Compostos de aminoheteroarilo como inibidores da proteína quinase
|
|
NZ543122A
(en)
|
2003-03-24 |
2008-07-31 |
Sequoia Pharmaceuticals Inc |
An HIV fusion inhibitor peptide covalently linked to a blood protein
|
|
WO2004094409A1
(en)
|
2003-03-27 |
2004-11-04 |
Lankenau Institute For Medical Research |
Novel ido inhibitors and methods of use
|
|
ZA200507752B
(en)
|
2003-03-28 |
2007-01-31 |
Threshold Pharmaceuticals Inc |
Compositions and methods for treating cancer
|
|
US7385055B2
(en)
|
2003-05-19 |
2008-06-10 |
Board Of Trustees Of Michigan State University |
Preparation of hymenialdisine derivatives and use thereof
|
|
US7842835B2
(en)
|
2003-07-07 |
2010-11-30 |
Georgetown University |
Histone deacetylase inhibitors and methods of use thereof
|
|
RU2006106768A
(ru)
|
2003-08-07 |
2007-09-20 |
Шеринг Корпорейшн (US) |
Новые ингибиторы фарнезилпротеинтрансферазы как противоопухолевые агенты
|
|
WO2005023246A1
(en)
|
2003-09-04 |
2005-03-17 |
Aventis Pharmaceuticals Inc. |
Substituted indoles as inhibitors of poly (adp-ribose) polymerase (parp)
|
|
HUP0303313A2
(hu)
|
2003-10-09 |
2005-07-28 |
Richter Gedeon Vegyészeti Gyár Rt. |
Transzdermális gyógyszerkészítmények
|
|
US7491725B2
(en)
|
2004-02-06 |
2009-02-17 |
Bristol-Myers Squibb Company |
Process for preparing 2-aminothiazole-5-aromatic carboxamides as kinase inhibitors
|
|
US8435539B2
(en)
|
2004-02-13 |
2013-05-07 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
US8652484B2
(en)
|
2004-02-13 |
2014-02-18 |
Immunomedics, Inc. |
Delivery system for cytotoxic drugs by bispecific antibody pretargeting
|
|
WO2005092326A1
(en)
|
2004-03-22 |
2005-10-06 |
The Regents Of The University Of Michigan |
Small molecule antagonists of xiap family proteins
|
|
CA2561617A1
(en)
|
2004-04-05 |
2005-10-20 |
Aton Pharma, Inc. |
Histone deacetylase inhibitor prodrugs
|
|
TW200538149A
(en)
|
2004-05-20 |
2005-12-01 |
Telik Inc |
Sensitization to another anticancer therapy and/or amelioration of a side effect of another anticancer therapy by treatment with a GST-activated anticancer compound
|
|
TW200600091A
(en)
|
2004-05-21 |
2006-01-01 |
Telik Inc |
Sulfonylethyl phosphorodiamidates
|
|
CA2568835C
(en)
|
2004-06-30 |
2014-05-27 |
Janssen Pharmaceutica N.V. |
Quinazolinone derivatives as parp inhibitors
|
|
SI1771474T1
(sl)
|
2004-07-20 |
2010-06-30 |
Genentech Inc |
Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba
|
|
SE0402025D0
(sv)
|
2004-08-13 |
2004-08-13 |
Active Biotech Ab |
Treatment of hyperproliferative disease with superantigens in combination with another anticancer agent
|
|
US20060100226A1
(en)
|
2004-09-10 |
2006-05-11 |
Sikorski James A |
2-Thiopyrimidinones as therapeutic agents
|
|
CA2595290C
(en)
|
2005-01-19 |
2013-06-25 |
Mgi Gp, Inc. |
Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting parp
|
|
NZ560712A
(en)
|
2005-02-17 |
2010-12-24 |
Synta Pharmaceuticals Corp |
(3,4,5-trisubstituted-phenyl)isoxazole combretastin derivatives for the treatment of disorders
|
|
US7872050B2
(en)
|
2005-03-14 |
2011-01-18 |
Yaupon Therapeutics Inc. |
Stabilized compositions of volatile alkylating agents and methods of using thereof
|
|
KR101288729B1
(ko)
|
2005-04-01 |
2013-07-23 |
인터자인 테크놀로지스, 인코포레이티드 |
약물 전달용 중합체성 마이셀
|
|
US20060229277A1
(en)
|
2005-04-08 |
2006-10-12 |
Orbus Pharma, Inc. |
Stabilized pharmaceutical compositions comprising an HMG-CoA reductase inhibitor
|
|
US7728026B2
(en)
|
2005-04-11 |
2010-06-01 |
Abbott Laboratories, Inc. |
2-substituted-1 h-benzimidazile-4-carboxamides are PARP inhibitors
|
|
US8242103B2
(en)
|
2005-05-19 |
2012-08-14 |
Merck Sharp & Dohme Limited |
Sulphamides for treatment of cancer
|
|
BRPI0613796A2
(pt)
|
2005-06-07 |
2011-02-15 |
Univ Yale |
composicões farmacêuticas e seus usos, e métodos de tratamento de cáncer e outras condições ou estados patológicos, por meio do uso de clevudina (lfmau) e telbivudina (ldt)
|
|
JP5159616B2
(ja)
|
2005-06-15 |
2013-03-06 |
カーディオム ファーマ コーポレイション |
アミノシクロヘキシルエーテル化合物の調製のための合成プロセス
|
|
RU2408584C2
(ru)
|
2005-06-23 |
2011-01-10 |
Мерк Шарп Энд Домэ Корп. |
Ингибиторы тирозинкиназы
|
|
HUE035853T2
(en)
|
2005-07-18 |
2018-05-28 |
Seattle Genetics Inc |
Beta-glucuronide-linker-drug conjugates
|
|
CA2621983A1
(en)
|
2005-09-09 |
2007-03-22 |
Schering Corporation |
Azafused cyclin dependent kinase inhibitors
|
|
US8378117B2
(en)
|
2005-09-23 |
2013-02-19 |
Janssen Pharmaceutica N.V. |
Hexahydro-cycloheptapyrazole cannabinoid modulators
|
|
EA015781B1
(ru)
|
2005-10-21 |
2011-12-30 |
Панацея Биотек Лимитед |
Композиции для лечения рака
|
|
JP5249770B2
(ja)
|
2005-11-03 |
2013-07-31 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
キナーゼインヒビターとして有用なアミノピリジン
|
|
WO2007065559A1
(en)
|
2005-11-18 |
2007-06-14 |
Synthon B.V. |
Zolpidem tablets
|
|
CA2633500A1
(en)
|
2005-12-20 |
2007-07-05 |
President And Fellows Of Harvard College |
Compounds, screens, and methods of treatment
|
|
WO2007081751A2
(en)
|
2006-01-05 |
2007-07-19 |
The Johns Hopkins University |
Compositions and methods for the treatment of cancer
|
|
US7910607B2
(en)
|
2006-03-10 |
2011-03-22 |
The Trustees Of California State University |
Nitroxide free radical synergized antineoplastic agents
|
|
WO2007106555A2
(en)
|
2006-03-14 |
2007-09-20 |
Neuren Pharmaceuticals Limited |
Oral formulations of glycyl-2-methylprolyl-glutamate
|
|
AU2007228784B2
(en)
|
2006-03-22 |
2012-03-08 |
Janssen Pharmaceutica N.V. |
Cyclic-alkylaminederivatives as inhibitors of the interaction between MDM2 and p53
|
|
CA2644369A1
(en)
|
2006-03-28 |
2007-10-04 |
Novartis Ag |
Amide derivatives and their application for the treatment of g protein related diseases
|
|
CA2645633A1
(en)
|
2006-04-05 |
2007-11-01 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
|
WO2007127137A2
(en)
|
2006-04-26 |
2007-11-08 |
Merck & Co., Inc. |
Disubstituted aniline compounds
|
|
GB0609378D0
(en)
|
2006-05-11 |
2006-06-21 |
Novartis Ag |
Organic compounds
|
|
CA2651681A1
(en)
|
2006-05-18 |
2007-11-29 |
Merck & Co., Inc. |
Aryl-fused spirocyclic compounds
|
|
US8034834B2
(en)
*
|
2006-05-25 |
2011-10-11 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders with HSP90 inhibitors
|
|
TWI490212B
(zh)
|
2006-05-25 |
2015-07-01 |
Synta Pharmaceuticals Corp |
調節hsp90活性之三唑化合物
|
|
EP2069351B1
(en)
|
2006-06-20 |
2015-10-28 |
AbbVie Inc. |
Pyrazoloquinazolinones as parp inhibitors
|
|
US7964728B2
(en)
|
2006-07-06 |
2011-06-21 |
Solvay Pharmaceuticals B.V. |
Azaindole derivatives with a combination of partial nicotinic acetyl-choline receptor agonism and dopamine reuptake inhibition
|
|
US20080213249A1
(en)
|
2006-07-07 |
2008-09-04 |
The Scripps Research Insitute |
Use of Retro-Aldol Reaction to Generate Reactive Vinyl Ketone for Attachment to Antibody Molecules by Michael Addition Reaction for Use in Immunostaining and Immunotargeting
|
|
TW200813021A
(en)
|
2006-07-10 |
2008-03-16 |
Merck & Co Inc |
Tyrosine kinase inhibitors
|
|
JP2009543823A
(ja)
|
2006-07-17 |
2009-12-10 |
ノバルティス アクチエンゲゼルシャフト |
免疫調節剤として使用するための胆汁酸アミドのスルホニルアミノカルボニル誘導体
|
|
MX2009000824A
(es)
|
2006-07-24 |
2009-02-04 |
Tetralogic Pharmaceuticals Cor |
Antagonistas dimericos de las proteinas inhibidoras de la apoptosis.
|
|
US7683060B2
(en)
|
2006-08-07 |
2010-03-23 |
Incyte Corporation |
Triazolotriazines as kinase inhibitors
|
|
AU2007281682B2
(en)
|
2006-08-07 |
2013-05-16 |
Abbvie Biotherapeutics Inc. |
Compositions and methods using anti-CS1 antibodies to treat multiple myeloma
|
|
CA2659425C
(en)
|
2006-08-17 |
2017-06-20 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
|
US20080085882A1
(en)
*
|
2006-08-18 |
2008-04-10 |
University Of North Texas Health Science Center At Fort Worth |
Compositions and Methods for Potentiation of Cancer Agents
|
|
ATE535520T1
(de)
|
2006-08-23 |
2011-12-15 |
Eisai R&D Man Co Ltd |
Salz eines phenoxypyridinderivats oder kristall davon und verfahren zu dessen herstellung
|
|
CN101501051A
(zh)
|
2006-08-23 |
2009-08-05 |
诺瓦提斯公司 |
作为神经磷脂酶抑制剂的酰胺化合物
|
|
DK2061765T3
(en)
|
2006-09-01 |
2015-01-26 |
Senhwa Biosciences Inc |
Serine-threonine protein kinase AND PARP-MODULATOR
|
|
WO2008030408A2
(en)
|
2006-09-05 |
2008-03-13 |
Yale University |
Proteomimetic compounds as inhibitors of the interaction of a nuclear receptor with coactivator peptides
|
|
EP2529621B1
(en)
|
2006-09-22 |
2016-10-05 |
Pharmacyclics LLC |
Inhibitors of bruton's tyrosine kinase
|
|
JP5721949B2
(ja)
|
2006-10-12 |
2015-05-20 |
アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited |
複合薬剤
|
|
US8242080B2
(en)
|
2006-10-13 |
2012-08-14 |
The Regents Of The University Of California |
Inhibitors of the EGFR kinase targeting the asymmetric activating dimer interface
|
|
UY30639A1
(es)
|
2006-10-17 |
2008-05-31 |
Kudos Pharm Ltd |
Derivados sustituidos de 2h-ftalazin-1-ona, sus formas cristalinas, proceso de preparacion y aplicaciones
|
|
US7842278B2
(en)
|
2006-10-27 |
2010-11-30 |
Natural Pharmacia International, Inc. |
Hypoxia-selective, weakly basic 2-nitroimidazole delivery agents and methods of use thereof
|
|
US8227605B2
(en)
|
2006-10-31 |
2012-07-24 |
Schering Corporation |
2-aminothiazole-4-carboxylic amides as protein kinase inhibitors
|
|
US7750007B2
(en)
|
2006-11-06 |
2010-07-06 |
Supergen, Inc. |
Imidazo[1,2-beta]pyridazine and pyrazolo[1,5-alpha]pyrimidine derivatives and their use as protein kinase inhibitors
|
|
US20120164075A1
(en)
|
2006-11-21 |
2012-06-28 |
Jina Pharmaceuticals, Inc. |
Endoxifen methods and compositions in the treatment of mammalian diseases
|
|
US20080125397A1
(en)
|
2006-11-28 |
2008-05-29 |
Telik, Inc. |
2 (SULFONYL)ETHYL N,N,N',N' tetrakis(2 chloroethyl)phosphorodia
|
|
US7655799B2
(en)
|
2006-11-29 |
2010-02-02 |
Telik, Inc. |
2{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidates
|
|
WO2008079973A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Egfr binding peptides and uses thereof
|
|
WO2008079982A2
(en)
|
2006-12-21 |
2008-07-03 |
Centocor, Inc. |
Liposome composition for targeting egfr receptor
|
|
US20080293648A1
(en)
|
2007-01-05 |
2008-11-27 |
Saha Pharmaceuticals, Inc. |
Compositions and Methods for Cancer Treatment
|
|
WO2008085987A2
(en)
|
2007-01-09 |
2008-07-17 |
The Trustees Of The University Of Pennsylvania |
Drug delivery to human tissues by single chain variable region antibody fragments cloned by phage display
|
|
US8398956B2
(en)
|
2007-01-11 |
2013-03-19 |
Immunomedics, Inc. |
In vivo copper-free click chemistry for delivery of therapeutic and/or diagnostic agents
|
|
MX2009008425A
(es)
|
2007-02-06 |
2009-08-17 |
Novartis Ag |
Derivados de 1-bencensulfonil-1h-indol como inhibidores de la actividad de ccr9.
|
|
CA2677651A1
(en)
|
2007-02-15 |
2008-08-21 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
|
MX2009009183A
(es)
|
2007-02-28 |
2009-09-07 |
Inotek Pharmaceuticals Corp |
Analogos de indenoisoquinolinona y metodos de utilizacion de los mismos.
|
|
JP5545955B2
(ja)
|
2007-03-08 |
2014-07-09 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
Parpおよびtank阻害剤としてのキノリノン誘導体
|
|
JP5383513B2
(ja)
|
2007-03-09 |
2014-01-08 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
化合物およびその標的に関連する組成物ならびに方法
|
|
US8501233B2
(en)
|
2007-03-13 |
2013-08-06 |
Wake Forest University |
Compositions and methods for treating cancer
|
|
US20100184706A1
(en)
|
2007-03-20 |
2010-07-22 |
Bachovchin William W |
Fap-activated chemotherapeutic compounds, and methods of use thereof
|
|
PT2139484E
(pt)
|
2007-04-10 |
2013-10-31 |
Exelixis Inc |
Métodos de tratamento de cancro usando inibidores piridopirimidinona de pi3k-alfa
|
|
US20100048579A1
(en)
|
2007-04-13 |
2010-02-25 |
Luca Arista |
Pyridazine-, pyridine- and pyrane-derivatives as gpbar1 agonists
|
|
PE20090806A1
(es)
|
2007-04-18 |
2009-06-27 |
Merck & Co Inc |
Derivados de triazol que son antagonistas de smo
|
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
|
AT505225A1
(de)
|
2007-04-26 |
2008-11-15 |
Sanochemia Pharmazeutika Ag |
0erfahren zur herstellung von hoch reinem 2,4'-dimethyl-3-piperidino-propiophenon (tolperison), dieses enthaltende pharmazeutische zusammensetzungen, sowie tolperison enthaltende wirkstoffformulierungen
|
|
US7838495B2
(en)
|
2007-04-27 |
2010-11-23 |
University Of Maryland, Baltimore |
Compositions and methods of use of EPB1, and ErbB3 binding protein
|
|
WO2008137619A2
(en)
|
2007-05-02 |
2008-11-13 |
Vertex Pharmaceuticals Incorporated |
Thiazoles and pyrazoles useful as kinase inhibitors
|
|
UA99914C2
(ru)
|
2007-05-15 |
2012-10-25 |
Оцука Фармас'Ютікел Ко., Лтд. |
Способ применения антагонистов вазопресина со средствами антрациклиновой химиотерапии для снижения кардиотоксичности
|
|
WO2008144506A1
(en)
|
2007-05-16 |
2008-11-27 |
University Of Maryland, Baltimore |
Apoptotic pathway targeting for the diagnosis and treatment of cancer
|
|
US20110288023A1
(en)
|
2007-06-08 |
2011-11-24 |
The Regents Of The University Of California Office Of Technology Transfer |
Cancer drug delivery using modified transferrin
|
|
WO2009003911A1
(en)
|
2007-06-29 |
2009-01-08 |
4Sc Ag |
Thiophene-imidazopyridines
|
|
WO2009008992A2
(en)
|
2007-07-06 |
2009-01-15 |
Osi Pharmaceuticals Inc. |
Combination anti-cancer therapy comprising an inhibitor of both mtorc1 and mt0rc2
|
|
PT2175884T
(pt)
|
2007-07-12 |
2016-09-21 |
Gitr Inc |
Terapias de combinação empregando moléculas de ligação a gitr
|
|
EP2545938A1
(en)
|
2007-08-03 |
2013-01-16 |
Abbott Biotherapeutics Corp. |
Therapeutic use of anti-tweak receptor antibodies
|
|
EP2184282B1
(en)
|
2007-08-10 |
2014-10-08 |
Mitsubishi Tanabe Pharma Corporation |
Novel salt of isoquinoline compound and crystal thereof
|
|
EP2190429B1
(en)
|
2007-09-10 |
2016-04-20 |
Boston Biomedical, Inc. |
A novel group of stat3 pathway inhibitors and cancer stem cell pathway inhibitors
|
|
SI2209375T1
(sl)
|
2007-10-03 |
2014-12-31 |
Eisai Inc. |
Spojine inhibitorja PARP in metode uporabe
|
|
US20100311678A1
(en)
|
2007-10-04 |
2010-12-09 |
Bean Bruce P |
Methods and compositions for treating cancer and modulating signal transduction and metabolism pathways
|
|
CN101903403B
(zh)
|
2007-10-19 |
2016-03-16 |
西雅图基因公司 |
Cd19结合剂及其应用
|
|
JP2011500806A
(ja)
|
2007-10-25 |
2011-01-06 |
メルク・シャープ・エンド・ドーム・コーポレイション |
治療用化合物
|
|
CN104109208A
(zh)
|
2007-11-14 |
2014-10-22 |
中外制药株式会社 |
使用抗gpr49抗体的癌症的诊断和治疗
|
|
JP5758630B2
(ja)
|
2007-11-15 |
2015-08-05 |
エンメエッセディ・イタリア・エッセ・エッレ・エッレ |
Parp阻害剤としてのピリダジノン誘導体
|
|
WO2009076629A2
(en)
|
2007-12-12 |
2009-06-18 |
The Regents Of The University Of Michigan |
Compositions and methods for treating cancer
|
|
EP2240172B1
(en)
|
2007-12-21 |
2014-03-19 |
Novartis AG |
Combination of nilotinib and chlorambucil for the treatment of chronic lymphocytic leukemia
|
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
|
CN101998959B
(zh)
|
2008-02-06 |
2013-08-28 |
生物马林药物股份有限公司 |
聚(adp-核糖)聚合酶(parp)的苯并噁唑甲酰胺抑制剂
|
|
BRPI0907754A2
(pt)
|
2008-02-08 |
2015-07-21 |
Aileron Therapeutics Inc |
Macrociclos peptidomiméticos terapêuticos
|
|
US20090202540A1
(en)
|
2008-02-11 |
2009-08-13 |
Auspex Pharmaceuticals, Inc. |
Substituted oxazaphosphorines
|
|
EP2259791A2
(en)
|
2008-03-05 |
2010-12-15 |
Tel HaShomer Medical Research Infrastructure and Services Ltd. |
Glp-1 receptor agonists and related active pharmaceutical ingredients for treatment of cancer
|
|
MY165582A
(en)
|
2008-03-11 |
2018-04-05 |
Incyte Holdings Corp |
Azetidine and cyclobutane derivatives as jak inhibitors
|
|
ES2480994T3
(es)
|
2008-03-31 |
2014-07-29 |
Genentech, Inc. |
Compuestos de tipo benzopirano y benzoxepina inhibidores de PI3K y métodos de uso
|
|
EP2110377A1
(en)
|
2008-04-15 |
2009-10-21 |
DAC S.r.l. |
Spirocyclic derivatives as histone deacetylase inhibitors
|
|
NZ588884A
(en)
|
2008-04-30 |
2013-05-31 |
Immunogen Inc |
Cross-linkers and their uses
|
|
US8158636B2
(en)
|
2008-05-19 |
2012-04-17 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
|
US8207169B2
(en)
|
2008-06-03 |
2012-06-26 |
Msd K.K. |
Substituted [1,2,4]triazolo[4′,3′:1,6]pyrido[2,3-b]pyrazines of the formula D
|
|
GB2475183B
(en)
|
2008-06-04 |
2011-11-23 |
Gw Pharma Ltd |
Cannabinoids in combination with non-cannabinoid chemotherapeutic agent that are selective estrogen receptor modulators
|
|
EP2133334A1
(en)
|
2008-06-09 |
2009-12-16 |
DAC S.r.l. |
Heterocyclic derivatives as HDAC inhibitors
|
|
US8207195B2
(en)
|
2008-06-26 |
2012-06-26 |
Inspire Pharmaceuticals, Inc. |
Method for treating neurological and neuropathic diseases using rho kinase inhibitor compounds
|
|
CA3012229C
(en)
|
2008-07-08 |
2020-11-10 |
Incyte Holdings Corporation |
1,2,5-oxadiazoles as inhibitors of indoleamine 2,3-dioxygenase
|
|
US8338477B2
(en)
|
2008-07-11 |
2012-12-25 |
Neumedics |
Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits
|
|
CA2726460C
(en)
|
2008-07-15 |
2017-02-21 |
F. Hoffmann-La Roche Ag |
Novel phenyl-imidazopyridines and pyridazines
|
|
CN102159214A
(zh)
|
2008-07-16 |
2011-08-17 |
药品循环公司 |
用于实体肿瘤的治疗的布鲁顿酪氨酸激酶的抑制剂
|
|
US8217076B2
(en)
|
2008-07-17 |
2012-07-10 |
Colorado State University Research Foundation |
Method for preparing largazole analogs and uses thereof
|
|
WO2010014755A1
(en)
|
2008-07-29 |
2010-02-04 |
The Regents Of The University Of Colorado |
Methods and compounds for enhancing anti-cancer therapy
|
|
WO2010021822A2
(en)
|
2008-07-30 |
2010-02-25 |
The Regents Of The University Of California |
Discovery of candidate biomarkers of in vivo apoptosis by global profiling of caspase cleavage sites
|
|
CA2732437C
(en)
|
2008-08-01 |
2017-11-21 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
|
HUE035295T2
(en)
|
2008-08-06 |
2018-05-02 |
Medivation Technologies Inc |
Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
|
|
BRPI0918971A2
(pt)
|
2008-08-26 |
2015-12-01 |
Boehringer Ingelheim Int |
tienopirimidinas para composições farmacêuticas
|
|
US20100068302A1
(en)
|
2008-09-17 |
2010-03-18 |
Traslational Cancer Drugs Pharma, S.L. |
Methods and compositions for the treatment of cancer
|
|
MX2011003751A
(es)
|
2008-10-08 |
2011-04-27 |
Cephalon Inc |
Procesos para preparar bendamustina.
|
|
US20100111901A1
(en)
|
2008-11-03 |
2010-05-06 |
Auspex Pharmaceuticals, Inc. |
Triazole inhibitors of aromatase
|
|
US8476431B2
(en)
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
|
UY32240A
(es)
|
2008-11-14 |
2010-06-30 |
Boeringer Ingelheim Kg |
Nuevas 2,4-diaminopirimidinas, sus sales farmacéuticamente aceptables, composiciones conteniéndolas y aplicaciones.
|
|
WO2010068920A2
(en)
|
2008-12-12 |
2010-06-17 |
Auspex Pharmaceutical, Inc. |
Diaminoquinazoline inhibitors of dihydrofolate reductase
|
|
WO2010080570A2
(en)
|
2008-12-18 |
2010-07-15 |
New York University |
Tumor therapy with antitumor agents in combination with sindbis virus-based vectors
|
|
US20100173013A1
(en)
|
2009-01-08 |
2010-07-08 |
Denis Drygin |
Treatment of neoplastic disorders using combination therapies
|
|
PL2389372T3
(pl)
|
2009-01-23 |
2016-02-29 |
Rigel Pharmaceuticals Inc |
Kompozycje i sposoby hamowania szlaku JAK
|
|
EP2389379A1
(en)
|
2009-01-23 |
2011-11-30 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-Ribose) Polymerase (PARP) Inhibitors
|
|
EP3620154A1
(en)
|
2009-02-06 |
2020-03-11 |
University Of Southern California |
Therapeutic compositions comprising monoterpenes
|
|
US8299077B2
(en)
|
2009-03-02 |
2012-10-30 |
Roche Palo Alto Llc |
Inhibitors of Bruton's tyrosine kinase
|
|
AR075812A1
(es)
|
2009-03-11 |
2011-04-27 |
Plexxikon Inc |
Derivados de pirrol[2,3-b]piridina como inhibidores de raf quinasa
|
|
BRPI1014854A2
(pt)
|
2009-03-30 |
2016-05-03 |
Cerulean Pharma Inc |
"conjugados polímero-agente, partículas, composições, e métodos de uso relacionados"
|
|
US8574829B2
(en)
|
2009-03-31 |
2013-11-05 |
The Trustees Of The University Of Pennsylvania |
Methods of treating cancer with phenformin
|
|
WO2010114881A1
(en)
|
2009-04-01 |
2010-10-07 |
Progenra Inc. |
Anti-neoplastic compounds, compositions and methods
|
|
JP5756457B2
(ja)
|
2009-04-06 |
2015-07-29 |
アジオス ファーマシューティカルズ, インコーポレイテッド |
ピルビン酸キナーゼm2調節剤、治療組成物および関連する使用方法
|
|
TW201040181A
(en)
|
2009-04-08 |
2010-11-16 |
Idenix Pharmaceuticals Inc |
Macrocyclic serine protease inhibitors
|
|
US20100291025A1
(en)
|
2009-04-13 |
2010-11-18 |
Auspex Pharmaceuticals, Inc. |
Indazole inhibitors of tyrosine kinase
|
|
ES2513915T3
(es)
|
2009-04-24 |
2014-10-27 |
F. Hoffmann-La Roche Ag |
Inhibidores de la tirosina quinasa de Bruton
|
|
US20110053968A1
(en)
|
2009-06-09 |
2011-03-03 |
Auspex Pharmaceuticals, Inc. |
Aminopyrimidine inhibitors of tyrosine kinase
|
|
WO2010144808A2
(en)
|
2009-06-12 |
2010-12-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Identification of dsg-3 as a biomarker for the detection of metastasis in lymph nodes
|
|
TWI625121B
(zh)
|
2009-07-13 |
2018-06-01 |
基利科學股份有限公司 |
調節細胞凋亡信號之激酶的抑制劑
|
|
US8232318B2
(en)
|
2009-07-31 |
2012-07-31 |
The General Hospital Corporation |
Approaches to treat cancer using HB-EGF inhibitors
|
|
SG178190A1
(en)
*
|
2009-07-31 |
2012-03-29 |
Shin Maeda |
Cancer metastasis inhibitor
|
|
AR077974A1
(es)
|
2009-08-28 |
2011-10-05 |
Takeda Pharmaceutical |
Compuestos de hexahidrooxazinopterina para uso como inhibidores de mtor
|
|
MX2012002994A
(es)
|
2009-09-11 |
2012-07-17 |
Cylene Pharmaceuticals Inc |
Lactamas heterociclo-substituidas farmaceuticamente utiles.
|
|
CN102647904A
(zh)
|
2009-09-16 |
2012-08-22 |
赛林药物股份有限公司 |
新型三环蛋白激酶调节剂
|
|
TWI423980B
(zh)
|
2009-09-28 |
2014-01-21 |
Hoffmann La Roche |
苯并氧氮呯pi3k抑制劑化合物及使用方法
|
|
US7741330B1
(en)
|
2009-10-12 |
2010-06-22 |
Pharmacyclics, Inc. |
Pyrazolo-pyrimidine inhibitors of Bruton's tyrosine kinase
|
|
MY173390A
(en)
|
2009-10-23 |
2020-01-22 |
Takeda Pharmaceuticals Co |
Anti-gcc antibody molecules and related compositions and methods
|
|
CA2780645C
(en)
|
2009-11-18 |
2018-01-16 |
Nektar Therapeutics |
Salt form of a multi-arm polymer-drug conjugate
|
|
PL2509602T3
(pl)
|
2009-12-04 |
2017-08-31 |
Senhwa Biosciences, Inc. |
Pirazolopirymidyny i podobne heterocykle jako inhibitory ck2
|
|
US20110195066A1
(en)
|
2010-02-05 |
2011-08-11 |
Auspex Pharmaceuticals, Inc. |
Quinoline inhibitors of tyrosine kinase
|
|
CA2825428C
(en)
|
2010-02-12 |
2022-06-14 |
Alexander Vuckovic, M.D., Llc |
Compositions and methods for treating depression
|
|
AU2011218805A1
(en)
|
2010-02-24 |
2012-08-30 |
Auspex Pharmaceuticals, Inc. |
Trimethoxyphenyl inhibitors of tyrosine kinase
|
|
ES2562959T3
(es)
|
2010-02-26 |
2016-03-09 |
Evotec International Gmbh |
Tienopirimidinas que contienen un grupo alquilo sustituido para composiciones farmacéuticas
|
|
UY33241A
(es)
|
2010-02-26 |
2011-09-30 |
Boehringer Ingelheim Int |
?Tienopirimidinas que contienen heterocicloalquilo para composiciones farmacéuticas?.
|
|
WO2011109799A1
(en)
|
2010-03-05 |
2011-09-09 |
Karyopharm Therapeutics, Inc. |
Nuclear transport modulatiors and uses thereof
|
|
AU2011243947A1
(en)
|
2010-04-23 |
2012-12-06 |
Piramal Enterprises Limited |
Nitric oxide releasing prodrugs of therapeutic agents
|
|
US9096584B2
(en)
|
2010-05-12 |
2015-08-04 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as inhibitors of ATR kinase
|
|
CA2800595C
(en)
|
2010-05-26 |
2018-04-24 |
Shriners Hospitals For Children |
Compositions comprising the nc2 domain of collagen ix and methods of using same
|
|
MX380504B
(es)
|
2010-06-03 |
2025-03-12 |
Pharmacyclics Llc |
El uso de inhibidores de la tirosina quinasa de bruton (btk).
|
|
WO2012047339A2
(en)
|
2010-06-28 |
2012-04-12 |
The General Hospital Corporation |
Anti-cxcr4 as a sensitizer to cancer therapeutics
|
|
BR112013003671A2
(pt)
*
|
2010-08-18 |
2017-01-10 |
Del Mar Pharmaceuticals |
composições e métodos para melhorar os benefícios terapêuticos de compostos químicos administyrados sub-otimamente incluindo hexitóis substituídos tais como dianidrogalactitol e diacetildianidrogalactiol
|
|
US20120213854A1
(en)
|
2010-09-30 |
2012-08-23 |
Fetzer Oliver S |
Methods of treating a subject and related particles, polymers and compositions
|
|
US8846623B2
(en)
|
2010-10-25 |
2014-09-30 |
Academia Sinica |
Cancer-targeting peptides and uses thereof in cancer treatment and diagnosis
|
|
WO2012064973A2
(en)
|
2010-11-10 |
2012-05-18 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
EP2786755A3
(en)
|
2010-11-12 |
2014-10-29 |
Pharma Mar S.A. |
Combination therapy with an antitumor alkaloid
|
|
WO2012166555A1
(en)
|
2011-05-27 |
2012-12-06 |
Nektar Therapeutics |
Water - soluble polymer - linked binding moiety and drug compounds
|
|
US8637490B2
(en)
|
2011-07-01 |
2014-01-28 |
Uwm Research Foundation, Inc. |
Anti-cancer agents
|
|
CA2842195A1
(en)
|
2011-07-18 |
2013-01-24 |
Immunomedics, Inc. |
Fty720 increases cd74 expression and sensitizes cancer cells to anti-cd74 antibody-mediated cell death
|
|
CN115778934A
(zh)
*
|
2012-01-20 |
2023-03-14 |
德玛公司 |
经取代的己糖醇类用于治疗恶性肿瘤的用途
|
|
KR101374820B1
(ko)
|
2012-01-30 |
2014-03-17 |
광주과학기술원 |
페오포르바이드-α 컨쥬게이트 및 그의 용도
|
|
US8501724B1
(en)
|
2012-01-31 |
2013-08-06 |
Pharmacyclics, Inc. |
Purinone compounds as kinase inhibitors
|
|
MA37711A1
(fr)
|
2012-06-04 |
2017-05-31 |
Pharmacyclics Inc |
Formes cristallines d'un inhibiteur de tyrosine kinase de bruton
|
|
US20140005148A1
(en)
|
2012-06-29 |
2014-01-02 |
Coldstream Laboratories Inc. |
Stable liquid formulations of nitrogen mustards
|