JP2016518154A - 電極パッドと共に使用するための制御ユニットおよび漏電を推定するための方法 - Google Patents
電極パッドと共に使用するための制御ユニットおよび漏電を推定するための方法 Download PDFInfo
- Publication number
- JP2016518154A JP2016518154A JP2016500610A JP2016500610A JP2016518154A JP 2016518154 A JP2016518154 A JP 2016518154A JP 2016500610 A JP2016500610 A JP 2016500610A JP 2016500610 A JP2016500610 A JP 2016500610A JP 2016518154 A JP2016518154 A JP 2016518154A
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- electrode pad
- pad
- ground
- active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R31/00—Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
- G01R31/50—Testing of electric apparatus, lines, cables or components for short-circuits, continuity, leakage current or incorrect line connections
- G01R31/52—Testing for short-circuits, leakage current or ground faults
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/16—Indifferent or passive electrodes for grounding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36114—Cardiac control, e.g. by vagal stimulation
- A61N1/36117—Cardiac control, e.g. by vagal stimulation for treating hypertension
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B18/1233—Generators therefor with circuits for assuring patient safety
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00026—Conductivity or impedance, e.g. of tissue
- A61B2017/0003—Conductivity or impedance, e.g. of tissue of parts of the instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22001—Angioplasty, e.g. PCTA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/0022—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00273—Anchoring means for temporary attachment of a device to tissue
- A61B2018/00279—Anchoring means for temporary attachment of a device to tissue deployable
- A61B2018/00285—Balloons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00404—Blood vessels other than those in or around the heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00505—Urinary tract
- A61B2018/00511—Kidney
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00815—Temperature measured by a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00821—Temperature measured by a thermocouple
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/16—Indifferent or passive electrodes for grounding
- A61B2018/162—Indifferent or passive electrodes for grounding located on the probe body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
- A61B2090/376—Surgical systems with images on a monitor during operation using X-rays, e.g. fluoroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Radiology & Medical Imaging (AREA)
- Cardiology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Otolaryngology (AREA)
- Plasma & Fusion (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- General Physics & Mathematics (AREA)
- Surgical Instruments (AREA)
- External Artificial Organs (AREA)
- Testing Of Short-Circuits, Discontinuities, Leakage, Or Incorrect Line Connections (AREA)
Abstract
Description
生体内医療用デバイスの第1の電極パッドおよび第2の電極パッドの間の漏電を判断する制御ユニットが、開示されている。第1の電極パッドは、第2の電極パッドから間隔をおいて配置され得る。第1の電極パッドは、活性電極および間隔をおいて配置した接地電極を有することができる。第2の電極パッドは、活性電極および接地電極を有することができる。第1の電極パッドの接地電極は、第2の電極パッドの接地電極に電気接続され得る。制御ユニットは、制御ユニットを生体内医療用デバイスに電気接続する入出力ブロック、および入出力ブロックに通信可能に結合されたコントローラを備え得る。コントローラは、生体内医療用デバイスの第1の電極パッドの活性電極に入出力ブロックを介して第1の信号を加え、それに応じて、第1の電極パッドの活性電極と第1の電極パッドの接地電極との間のインピーダンスに関連する測定値を判断するようにプログラミングされ得る。コントローラはまた、生体内医療用デバイスの第2の電極パッドの活性電極に入出力ブロックを介して第2の信号を加え、それに応じて、第2の電極パッドの活性電極と第2の電極パッドの接地電極との間のインピーダンスに関連する測定値を判断するようにプログラミングされ得る。加えて、コントローラは、第2の電極パッドの活性電極と第2の電極パッドの接地電極との間のインピーダンスに関連する測定値を使用して、第1の電極パッドの活性電極と第2の電極パッドの接地電極との間の漏電の推定値を判断するようにプログラミングされ得る。
式中、M1は第1の測定したインピーダンスであり、Z1は対象インピーダンスであり、Z12は漏洩インピーダンスである。
式中、M1は第1の測定したインピーダンスであり、Z1は対象インピーダンスであり、Z12は漏洩インピーダンスである。
全ての数値は本願明細書では、明確に示されているかどうかに拘わらず、「約」という用語によって変更されるものと考えられる。「約」という用語は普通、当業者が言及した値と同等である(すなわち、同じ機能および結果を有する)と考える数の範囲のことを言う。多くの例では、「約」という用語は、最も近い有効数字に四捨五入された数字を含み得る。
本願明細書および添付の特許請求の範囲で使用されるように、単数形「a」、「an」、および「the」は、内容が明らかにそうでないと示していない限り、複数の指示対象を含む。本願明細書および添付の特許請求の範囲で示されるように、「または」という用語は普通、内容が明らかにそうでないと示していない限り、「および/または」を含む意味で利用される。
(システム概要)
図1Aは、身体通路内で治療を行うシステム100を示している。システム100は、制御ユニット110を備えている。制御ユニット110は、カテーテル・デバイス120にRFエネルギーを運搬するためのRF発生器を備えることができる。本願明細書に開示された実施形態で使用可能な例示的な制御ユニットおよび関連エネルギー運搬方法は、本願明細書に援用する、同一譲受人の米国特許出願公開第2012/0095461号に開示されている。本願明細書に開示された実施形態で使用可能な別の例は、同一譲受人の「アテロームおよび他の対象組織および/または構造の選択的治療用同調RFエネルギー(Tuned RF Energy for Selective Treatment of Atheroma and Other Target Tissues and/or Structures)」という名称の米国特許第7,742,795号、「アテローム性物質の選択可能偏心リモデリングおよび/またはアブレーション(selectable Eccentric Remodeling and/or Ablation of Atherosclerotic Material)」という名称の米国特許第7,291,146号、および「身体組織上の望ましい温度効果を誘導するシステム(System for Inducing Desirable Temperature Effects on Body Tissue)」という名称の米国特許出願公開第2008/0188912号に開示されており、その全体の開示を本願明細書に援用する。いくつかの実施形態では、特に単極エネルギー運搬を利用するいくつかの実施形態では、システムはまた、カテーテル・デバイスに関連し得る接地/共通電極、制御ユニット110に電気結合された、あるいはシステム100に関連する別個のパッドを備えることもできる。
(拡張可能デバイスおよび電極アセンブリ)
再び図1Aを参照すると、カテーテル・デバイス120は、対応、非対応、または半対応バルーンである可能性がある拡張可能デバイス130を備え得る。拡張可能デバイス130は、制御ユニット110に電気結合された複数の電極アセンブリを備える。このような電極アセンブリは、単極または双極であるように電気的に構成することができ、さらに、感熱能力を有する。
(a.重複および非重複治療区域)
再び図1Bを参照すると、治療区域A〜Dは、長手軸L−Lに沿って互いに長手方向に隣接しており、電極アセンブリによって加えられるエネルギーが重複しない治療を作り出すように構成することができる。長手方向に隣接した双極電極アセンブリ140a〜140dによって加えられた治療は、長手軸L−Lに沿って周方向に非連続である。例えば、図1Cを参照すると、治療区域Aに作り出された損傷は、いくつかの実施形態では、治療区域Bに作り出された損傷との(この図でL−Lに対して横方向に)周面周りでの重複を最小限に抑えることができる。
(b.電極アセンブリ構造)
再び図1Cを参照すると、各電極パッド・アセンブリは、遠位電極パッド150a〜150dで、中間尾部160a〜160dで、近接電極パッド170a〜170d、および近接尾部180b、180d(電極パッド・アセンブリ140bおよび140cでは図示せず)である、4つの主な要素を含む。電極アセンブリ140a〜140dの構造的詳細は、図2A〜図2Cを参照して図示および記載されている。
図2Bは、遠位電極パッド208の部分断面A−Aを示している。電極222は図では、(導電層204)の接地トレース210の細長い電極支持体216に電極222を結合させることを可能にするために、複数の通路(例えば、孔)を有する絶縁層206の一部にわたって層状になっている。
図5Cは、電極アセンブリ500と同様に構成されているが、電極パッド512およびより多くの電極上により相対的な電極表面積を有する電極アセンブリ510を示している。
図5Eは、電極アセンブリ500と同様に構成されているが、電極パッド516およびより少ない電極518上にあまり相対的ではない電極表面積を有する電極アセンブリ514を示している。電極パッド516はまた、電極と同じ側に取り付けられた2つの感熱デバイス520を組み込む。
図2から図5Fの電極アセンブリは、双極または単極構成で使用することができる。図5Gから図5Iは、単極電極構成の追加の例を示している。図5Gでは、温度センサ532の両側に単極電極530の2つの平行アレイがある。図5Gでは、単極電極530の各アレイは、その独自の別個のトレースを有し、温度センサ532もその独自の別個のトレースを有する。しかし、他の実施形態では、特定のフレックス回路アセンブリ上の単極電極530の全ては単一の活性トレースを共有し、温度センサの2つのトレースの1つも共有することができるが、他の実施形態では、温度センサ用の電力および接地トレースは、1つまたは複数の単極トレースとは別であり得る。
(治療方法および制御システム)
(a.デバイス位置決め)
図6は、開示の1つの非限定的実施形態による、治療方法600を行うために使用されている、図1Aのシステム100を示している。ここで、制御ユニット110は図では、(複数の電極アセンブリを有する)拡張可能デバイスが、治療が必要な身体通路の部分S1に隣接して配置されるように、身体通路内に配置されたカテーテル・デバイスに動作可能に結合されている。部分S1でのカテーテル・デバイスの配置は、従来の方法により、例えば、透視下でガイドワイヤの上で行うことができる。
(b.エネルギー運搬)
必要な特定のリモデリング効果によって、制御ユニットは、1から180秒の間、約0.25から5ワット平均電力で、または約0.25から900ジュールで電極に通電する。より高いエネルギー治療を、90秒間0.5ワット、または180秒間0.25ワットなどの、より低い電力およびより長い持続時間で行うことができる。単極実施形態では、制御ユニットは、電極構成、および電極と共通接地との間の距離によって、最長5分間最大30ワットで電極に通電することができる。エネルギーは、より少ない導電損失でより局所化された領域にわたって進むので、より短い距離はより短い期間にわたってより低いエネルギーを与える。脱腎神経化で使用される例示的な実施形態では、約5ワットの治療設定で約30秒間エネルギーが運搬され、それによって、治療区域が治療中に約68℃まで加熱される。上に記したように、電力要求は、電極タイプおよび構成によって大きく左右される。普通、より幅広い電極間隙では、より多くの電力が必要であり、この場合、平均電力は5ワットより高く、合計エネルギーは45ジュールを超えることがある。同様に、より短いまたは小さい電極対を使用する場合は、平均電力を減らす必要があり、合計エネルギーは4ジュール未満になることがある。電力および持続時間は、いくつかの例では、厳しい損傷を引き起こすのに十分なのより小さく、特に、血管内の疾病組織をアブレーションするのに十分なのより小さいようにキャリブレーションされることがある。開示全体を本願明細書に援用する、スラガー(Slager)らによって、J.of Amer.Cardiol.(1985年6月)、第1382〜6ページの「放電加工によるアテローム動脈硬化性プラークの蒸発(Vaporization of Atherosclerotic Plaque by Spark Erosion)」というタイトルの記事において、およびステファン・エム・フライ(Stephan M.Fry)による、「熱および崩壊血管形成術:外科医のガイド(Thermal and Disruptive Angioplasty: a Physician’s Guide)」、ストラテジック・ビジネス・デベロップメント・インコーポレイテッド(Strategic Business Development, Inc.)、1990年によって、血管内のアテローム動脈硬化性物質をアブレーションする機構が、十分記載されている。
(c.対象温度)
RFエネルギーの付加は、対象および/または側枝組織の温度を制限するように制御して、例えば、対象組織も側枝組織も不可逆熱損傷を維持するように、対象組織の加熱を制限することができる。いくつかの実施形態では、表面温度範囲は約50度から約90℃までである。穏やかな加熱では、表面温度は約50℃から約70℃までの範囲であり、より活動的な加熱では、表面温度は約70℃から約90℃までの範囲である。バルク組織温度がほとんど50℃から55℃の下のままであるように、約50℃から約70℃までの範囲の表面温度未満に側枝組織の加熱を抑制するように加熱を制限することにより、そうでなければ、狭窄、熱損傷などにつながることがある免疫反応を抑制することができる。50℃から70℃の間の比較的穏やかな表面温度は、より大きい血管管腔、および改善された血流を提供するように、治療中、治療の直後、および/または治療に対する組織の治癒反応による治療後、1時間、1日、1週間、さらには1か月より長くタンパク質結合を変性および損傷させるのに十分である場合がある。
(d.制御アルゴリズム)
図13および図14は、上に記載し、図1〜図6に示したような電気外科用デバイス、または、上に記載し、図7〜図10に示したような、対象温度プロファイル、もしくは他のプロファイルに基づく他のデバイスのエネルギー付加を制御する方法の1つの実施形態を示している。制御方法は、上でさらに詳細に説明した、または他の方法での、図1の制御ユニット110、および/または制御ソフトウェアの処理機能を使用して実行することができる。少なくともいくつかの例では、制御方法は、システムの費用、寸法および複雑性を最小限に抑えることができる、単一の出力設定(例えば、電圧)で電極または他の運搬部位のいくつかに同時に通電するために、比較的単純なロバスト・エネルギー発生器を使用しながら、デバイスの様々な治療部位で温度または(1つまたは複数の)治療パラメータを細かく調整する。制御方法は、対象温度または(1つまたは複数の)治療パラメータからの逸脱を最小限に抑え、したがって、治療のあらゆる短い時間の間にエネルギー発生器に関する需要(例えば、電圧需要)の変化を最小限に抑える。
ステップ1300で示すように、各電極は最初にオフに設定される。ステップ1302では、電極の1本が、その治療サイクルに対する一次電極として指定される。以下にさらに詳細に論じるように、治療中、指定された一次電極は、治療サイクルから治療サイクルまで(例えば、利用可能な電極全てを通るサイクル)で変化する。どの電極が一次電極として指定されるかの判断は、参照テーブルにアクセスする、またはあらゆる他の適切な機能を使用して、一次電極を識別し、治療サイクルから治療サイクルまでの一次電極の選択を変更することによって行うことができる。
ステップ1314では、通電される電極が現在、60℃より高い温度であるか判断される。68℃より高い温度であるこれらの電極は、オフに切り換えられる、あるいは、その治療サイクルで通電されるのが防止され、あるいは他の状態で上記基準を満たすこれらの電極は、ステップ1316において設定電極で通電される。したがって、別の治療サイクルが始まり、図13の制御ループは、治療が完了するまで繰り返される。いくつかの実施形態では、各治療サイクルは、前のおよび次のサイクルと非重複である(例えば、図13のステップは、次のサイクルのステップが開始する前に完全に行われる)が、他の実施形態では、サイクルは少なくともある程度重複していることもある。
(e.神経信号刺激および監視)
上に記載した実施形態の少なくともいくつかでは、または代替実施形態では、脱腎神経化治療方法およびシステムは、神経信号の刺激、および治療した腎動脈に近接する組織内の神経信号反応の監視を行う。いくつかの例では、神経活性のこのような電気記録図は、脱神経化治療の有効性の評価を行う、および/または治療を調整するためのフィードバックを行うことができる。少なくともいくつかの実施形態では、このような電気記録図は、神経活性が存在する、および/または測定した基準に対してシフト(例えば、減少)したかどうかの評価を行い、腎動脈に近接した腎組織の存在をマッピングまたは定量化する必要はない。
(小さな/分岐血管および他の通路の治療)
本明細書に記載したシステムおよびデバイスは有利には、他のエネルギー・ベース治療システムおよびデバイスが適切でない状況で使用することができる。例えば、本明細書に記載したシステムおよびデバイスの実施形態を、血管、および他のカテーテル・ベースエネルギー治療システムを使用して治療するのには小さすぎる他の通路で使用することができる。いくつかの例では、本明細書に記載したシステムおよびデバイスは、4mm未満の直径、および/または20mm未満の長さを有する腎動脈または他の血管で使用することができる。血管蛇行、および治療を受けるべきでない領域に対する治療部位への近接などの他の要因は、現在記載したシステムおよびデバイスの少なくともいくつかの実施形態に対してではないが、前のデバイスを使用した治療に対する反対の表示、あるいは適切ではないことがある。
(インピーダンス補償)
本願明細書に示すように、双極対の電極を使用して、腎神経を含む組織をアブレーションする、変調する、あるいはリモデリングすることもできる。考えられる電極の少なくともいくつかは、遠位電極パッド5050上の遠位対の双極電極(例えば、対の双極電極は、1つまたは複数の活性電極および1つまたは複数の接地電極を含む)、および近接電極パッド5070上の近接対の双極電極(例えば、対の双極電極は、1つまたは複数の活性電極および1つまたは複数の接地電極を含む)でバルーン上に取り付けることができる、図51に略図的に示した可撓性回路および/または2個組5040上に配置され得る。上に示すように、遠位電極パッド5050、近接電極パッド5070、または両方とも、温度センサ(例えば、サーミスタ)を備えることができる。
この関係は、方程式(1)内に代入し、以下の通り、Z1に対して解を求めることができる。
MZ2は、近接電極パッド5070上の双極電極間の測定したインピーダンスである。
分かるように、測定したインピーダンスMZ1は、遠位電極パッド5050上の双極電極間の実際のインピーダンスZ1のより優れた近似を行うためにこの一次方程式(3)を使用して補償することができる。一次関数がここに示されているが、非一次関数を使用することもできることが考えられる。いくつかの例では、一次および/または非一次関数はまた、温度、インピーダンス測定値MZ1および/またはMZ2を得るために加えられる電圧信号、および/または必要に応じてあらゆる他の適切なパラメータの関数であってもよい。
Claims (15)
- 生体内医療用デバイスの第1の電極パッドおよび第2の電極パッドの間の漏電を判断する制御ユニットにおいて、該第1の電極パッドが該第2の電極パッドから間隔をおいて配置されており、該第1の電極パッドが活性電極および間隔をおいて配置されている接地電極を有し、該第2の電極パッドが活性電極および接地電極を有し、該第1の電極パッドの該接地電極が該第2の電極パッドの該接地電極に電気接続されている制御ユニットであって、
該制御ユニットを該生体内医療用デバイスに電気接続する入出力ブロックと、
該入出力ブロックに通信可能に結合されるコントローラであって、
該生体内医療用デバイスの該第1の電極パッドの該活性電極に該入出力ブロックを介して第1の信号を加え、それに応じて、該第1の電極パッドの該活性電極と該第1の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該生体内医療用デバイスの該第2の電極パッドの活性電極に該入出力ブロックを介して第2の信号を加え、それに応じて、該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該インピーダンスに関連する該測定値を使用して、該第1の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該漏電の推定値を判断するようにプログラミングされているコントローラとを備えた制御ユニット。 - 前記コントローラはさらに、前記第1の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記漏電の前記推定値に基づいて、前記第1の電極パッドの前記活性電極と前記第1の電極パッドの前記接地電極との間のインピーダンスに関連する前記測定値を補償するようにプログラミングされている、請求項1に記載の制御ユニット。
- 前記第1の電極パッドは、第1の活性電極トレースと共に接続された2本以上の活性電極、および第1の接地電極トレースと共に接続された2本以上の間隔をおいて配置された接地電極を有し、
前記第2の電極パッドは、第2の活性電極トレースと共に接続された2本以上の活性電極、および第2の接地電極トレースと共に接続された2本以上の間隔をおいて配置された接地電極を有し、
該第1の電極トレースが、該第2の電極トレースに電気接続されて、共通の接地電極トレースを形成し、
前記制御ユニットの前記入出力ブロックは、前記制御ユニットを該第1の活性電極トレース、該第2の活性電極トレース、および該共通の接地電極トレースに電気接続させる、請求項1に記載の制御ユニット。 - 前記生体内医療用デバイスはさらに、前記第1の電極パッドおよび前記第2の電極パッドから間隔をおいて配置された第3の電極パッドを備え、該第3の電極パッドは、活性電極および間隔をおいて配置された接地電極を有し、該第3の電極パッドの該接地電極は、前記第1の電極パッドおよび前記第2の電極パッドの前記接地電極に電気接続されており、
前記制御ユニットの前記コントローラはさらに、
前記生体内医療用デバイスの該第3の電極パッドの該活性電極に前記入出力ブロックを介して第3の信号を加え、それに応じて、該第3の電極パッドの該活性電極と該第3の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該第3の電極パッドの該活性電極と該第3の電極パッドの該接地電極との間の該インピーダンスに関連する該測定値を使用して、前記第1の電極パッドの前記活性電極と該第3の電極パッドの該接地電極との間の漏電の推定値を判断するようにプログラミングされている、請求項1に記載の制御ユニット。 - 前記コントローラは、前記第2の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記インピーダンスに関連する前記測定値を定数に掛けることによって、前記第1の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記漏電の前記推定値を判断する、請求項1に記載の制御ユニット。
- 前記定数は、経験的データによって判断される、請求項5に記載の制御ユニット。
- 前記コントローラは、一次関数で、前記第2の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記インピーダンスに関連する前記測定値を使用することによって、前記第1の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記漏電の前記推定値を判断する、請求項1に記載の制御ユニット。
- 前記コントローラは、非一次関数で、前記第2の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記インピーダンスに関連する前記測定値を使用することによって、前記第1の電極パッドの前記活性電極と前記第2の電極パッドの前記接地電極との間の前記漏電の前記推定値を判断する、請求項1に記載の制御ユニット。
- 前記非一次関数は、前記加えられた信号の温度および電圧の1つまたは複数に左右される、請求項8に記載の制御ユニット。
- 前記コントローラは、前記生体内医療用デバイスの前記第2の電極パッドの前記活性電極に前記入出力ブロックを介して前記信号を加える前または後に、前記生体内医療用デバイスの前記第1の電極パッドの前記活性電極に前記入出力ブロックを介して前記信号を加えるようにプログラミングされている、請求項1に記載の制御ユニット。
- 前記コントローラは、前記生体内医療用デバイスの前記第2の電極パッドの前記活性電極に前記入出力ブロックを介して前記信号を加えると同時に、前記生体内医療用デバイスの前記第1の電極パッドの前記活性電極に前記入出力ブロックを介して前記信号を加えるようにプログラミングされている、請求項1に記載の制御ユニット。
- 生体内医療用デバイスの第1の電極パッドと第2の電極パッドとの間の漏電を判断する方法において、該第1の電極パッドが該第2の電極パッドから間隔をおいて配置されており、該第1の電極パッドが活性電極および間隔をおいて配置されている接地電極を有し、該第2の電極パッドが活性電極および接地電極を有し、該第1の電極パッドの該接地電極が該第2の電極パッドの該接地電極に電気接続されている方法であって、
該生体内医療用デバイスの該第1の電極パッドの該活性電極に第1の信号を加え、これに応じて、該第1の電極パッドの該活性電極と該第1の電極パッドの該接地電極の間のインピーダンスに関連する測定値を判断する工程と、
該生体内医療用デバイスの該第2の電極パッドの該活性電極に第2の信号を加え、これに応じて、該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断する工程と、
該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該インピーダンスに関連する該測定値を使用して、該第1の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該漏電の推定値を判断する工程と、
該第1の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該漏電の該推定値に基づいて、該第1の電極パッドの該活性電極と該第1の電極パッドの該接地電極との間のインピーダンスに関連する該測定値を補償する工程とを含む方法。 - 第1の電極パッドおよび第2の電極パッドを有する生体内医療用デバイスであって、該第1の電極パッドは、該第2の電極パッドと間隔をおいて配置されており、該第1の電極パッドは、活性電極および間隔をおいて配置された接地電極を有し、該第2の電極パッドは、活性電極および接地電極を有し、該第1の電極パッドの該接地電極は、該第2の電極パッドの該接地電極に電気接続されている生体内医療用デバイスと、
該生体内医療用デバイスに結合された制御ユニットであって、
該生体内医療用デバイスの該第1の電極パッドの該活性電極に第1の信号を加え、これに応じて、該第1の電極パッドの該活性電極と該第1の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該生体内医療用デバイスの該第2の電極パッドの該活性電極に第2の信号を加え、これに応じて、該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該第2の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該インピーダンスに関連する該測定値を使用して、該第1の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の漏電の推定値を判断し、
該第1の電極パッドの該活性電極と該第2の電極パッドの該接地電極との間の該漏電の該推定値に基づいて、該第1の電極パッドの該活性電極と該第1の電極パッドの該接地電極との間のインピーダンスに関連する該測定値を補償するようにプログラミングされている制御ユニットとを備えたシステム。 - 前記生体内医療用デバイスの前記第1の電極パッドは、第1の活性電極トレースと共に接続された2本以上の活性電極、および第1の接地電極トレースと共に接続された2本以上の間隔をおいて配置された接地電極を有し、
前記生体内医療用デバイスの前記第2の電極パッドは、第2の活性電極トレースと共に接続された2本以上の活性電極、および第2の接地電極トレースと共に接続された2本以上の間隔をおいて配置された接地電極を有し、
該第1の電極トレースが、該第2の電極トレースに電気接続されて、共通の接地電極トレースを形成し、
前記制御ユニットは、前記第1の活性電極トレース、前記第2の活性電極トレース、および前記共通の接地電極トレースに電気接続されている、請求項13に記載のシステム。 - 前記生体内医療用デバイスはさらに、前記第1の電極パッドおよび前記第2の電極パッドから間隔をおいて配置された第3の電極パッドを備え、該第3の電極パッドは、活性電極および間隔をおいて配置された接地電極を有し、該第3の電極パッドの該接地電極は、前記第1の電極パッドおよび前記第2の電極パッドの前記接地電極に電気接続されており、
前記制御ユニットはさらに、前記生体内医療用デバイスの該第3の電極パッドの該活性電極に第3の信号を加え、それに応じて、該第3の電極パッドの該活性電極と該第3の電極パッドの該接地電極との間のインピーダンスに関連する測定値を判断し、
該第3の電極パッドの該活性電極と該第3の電極パッドの該接地電極との間の該インピーダンスに関連する該測定値を使用して、前記第1の電極パッドの前記活性電極と該第3の電極パッドの該接地電極との間の漏電の推定値を判断するようにプログラミングされている、請求項13に記載のシステム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361788429P | 2013-03-15 | 2013-03-15 | |
US61/788,429 | 2013-03-15 | ||
PCT/US2014/020368 WO2014149690A2 (en) | 2013-03-15 | 2014-03-04 | Medical devices and methods for treatment of hypertension that utilize impedance compensation |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2016518154A true JP2016518154A (ja) | 2016-06-23 |
JP6139772B2 JP6139772B2 (ja) | 2017-05-31 |
Family
ID=50288349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016500610A Expired - Fee Related JP6139772B2 (ja) | 2013-03-15 | 2014-03-04 | 電極パッドと共に使用するための制御ユニットおよび漏電を推定するための方法 |
Country Status (6)
Country | Link |
---|---|
US (2) | US9297845B2 (ja) |
EP (1) | EP2967725B1 (ja) |
JP (1) | JP6139772B2 (ja) |
CN (1) | CN105228546B (ja) |
AU (1) | AU2014237950B2 (ja) |
WO (1) | WO2014149690A2 (ja) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
US20070021803A1 (en) | 2005-07-22 | 2007-01-25 | The Foundry Inc. | Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction |
ATE494040T1 (de) | 2006-06-28 | 2011-01-15 | Ardian Inc | Systeme für wärmeinduzierte renale neuromodulation |
EP3449856B1 (en) | 2010-10-25 | 2023-06-28 | Medtronic Ardian Luxembourg S.à.r.l. | Device for evaluation and feedback of neuromodulation treatment |
JP5759615B2 (ja) | 2011-04-08 | 2015-08-05 | コヴィディエン リミテッド パートナーシップ | 腎交感神経の除神経およびイオン導入薬物送達のためのイオン導入カテーテルシステムならびに方法 |
WO2013076588A2 (en) | 2011-11-07 | 2013-05-30 | Medtronic Ardian Luxembourg S.A.R.L. | Endovascular nerve monitoring devices and associated systems and methods |
JP6195856B2 (ja) | 2012-03-08 | 2017-09-13 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | 神経調節装置に関するバイオマーカーのサンプリングならびに関連システムおよび方法 |
AU2013308531B2 (en) | 2012-08-31 | 2018-05-10 | Acutus Medical, Inc. | Catheter system and methods of medical uses of same, including diagnostic and treatment uses for the heart |
EP2968919B1 (en) | 2013-03-15 | 2021-08-25 | Medtronic Ardian Luxembourg S.à.r.l. | Controlled neuromodulation systems |
EP2967725B1 (en) * | 2013-03-15 | 2019-12-11 | Boston Scientific Scimed, Inc. | Control unit for detecting electrical leakage between electrode pads and system comprising such a control unit |
US9339332B2 (en) | 2013-08-30 | 2016-05-17 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation catheters with nerve monitoring features for transmitting digital neural signals and associated systems and methods |
US9326816B2 (en) | 2013-08-30 | 2016-05-03 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation systems having nerve monitoring assemblies and associated devices, systems, and methods |
US10433902B2 (en) | 2013-10-23 | 2019-10-08 | Medtronic Ardian Luxembourg S.A.R.L. | Current control methods and systems |
AU2014360318B2 (en) | 2013-12-05 | 2019-10-31 | Rfemb Holdings, Llc | Cancer immunotherapy by radiofrequency electrical membrane breakdown (RF-EMB) |
EP3424453A1 (en) * | 2014-02-04 | 2019-01-09 | Boston Scientific Scimed, Inc. | Alternative placement of thermal sensors on bipolar electrode |
US9956035B2 (en) * | 2014-03-27 | 2018-05-01 | Biosense Webster (Israel) Ltd. | Temperature measurement in catheter |
US10610292B2 (en) | 2014-04-25 | 2020-04-07 | Medtronic Ardian Luxembourg S.A.R.L. | Devices, systems, and methods for monitoring and/or controlling deployment of a neuromodulation element within a body lumen and related technology |
US10709490B2 (en) | 2014-05-07 | 2020-07-14 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter assemblies comprising a direct heating element for renal neuromodulation and associated systems and methods |
US11154712B2 (en) | 2014-08-28 | 2021-10-26 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for assessing efficacy of renal neuromodulation and associated systems and devices |
EP4389044A2 (en) | 2014-10-01 | 2024-06-26 | Medtronic Ardian Luxembourg S.à.r.l. | Systems and methods for evaluating neuromodulation therapy via hemodynamic responses |
US20160135878A1 (en) * | 2014-11-14 | 2016-05-19 | General Electric Company | System and method for nervous system modulation |
WO2016100720A1 (en) | 2014-12-17 | 2016-06-23 | Medtronic Ardian Luxembourg S.A.R.L. | Systems and methods for assessing sympathetic nervous system tone for renal neuromodulation therapy |
WO2016123608A2 (en) * | 2015-01-30 | 2016-08-04 | Rfemb Holdings, Llc | Radio-frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue |
US11020181B2 (en) | 2016-01-07 | 2021-06-01 | Educational Foundation Kyorin Gakuen | Infrared denaturing device |
JP2019503398A (ja) | 2016-01-15 | 2019-02-07 | アールエフイーエムビー ホールディングス リミテッド ライアビリティ カンパニー | がんの免疫学的処置 |
US11172991B2 (en) | 2016-09-08 | 2021-11-16 | Medtronic, Inc. | Navigation with arbitrary catheter geometries and method of contact assessment |
US10231784B2 (en) | 2016-10-28 | 2019-03-19 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and systems for optimizing perivascular neuromodulation therapy using computational fluid dynamics |
US11147610B2 (en) * | 2017-02-10 | 2021-10-19 | Biosense Webster (Israel) Ltd. | Tissue thickness using pulsed power |
CN114311659A (zh) | 2017-05-16 | 2022-04-12 | 南京三迭纪医药科技有限公司 | 3d打印设备和方法 |
EP3459469A1 (en) | 2017-09-23 | 2019-03-27 | Universität Zürich | Medical occluder device |
US10201503B1 (en) | 2018-01-09 | 2019-02-12 | Triastek, Inc. | Precision pharmaceutical 3D printing device |
US11123135B2 (en) * | 2018-05-30 | 2021-09-21 | Biosense Webster (Israel) Ltd. | Enhanced large-diameter balloon catheter |
US11633120B2 (en) | 2018-09-04 | 2023-04-25 | Medtronic Ardian Luxembourg S.A.R.L. | Systems and methods for assessing efficacy of renal neuromodulation therapy |
US11458684B2 (en) | 2020-07-30 | 2022-10-04 | Triastek, Inc. | High-throughput and high-precision pharmaceutical additive manufacturing system |
CN117301512A (zh) | 2019-08-20 | 2023-12-29 | 南京三迭纪医药科技有限公司 | 高通量和高精度的药物增材制造系统 |
US11944315B2 (en) | 2019-09-26 | 2024-04-02 | Universität Zürich | Left atrial appendage occlusion devices |
TW202139937A (zh) * | 2020-03-05 | 2021-11-01 | 愛爾蘭商博士健康愛爾蘭有限公司 | 具有用於熱量測之非接觸式溫度感測的電極組件 |
WO2021239848A1 (en) * | 2020-05-27 | 2021-12-02 | Galvez Gamiz Manuel | Electrophysiology system |
US11793565B2 (en) | 2020-09-29 | 2023-10-24 | Biosense Webster (Israel) Ltd. | Detecting electrode contact using absolute and relative thresholds |
US11911096B2 (en) | 2020-12-17 | 2024-02-27 | Biosense Webster (Israel) Ltd. | Detecting contact and proximity between ablation electrodes by sensing changes in voltage morphology of non-activated electrodes |
CN113349882B (zh) * | 2021-06-23 | 2022-12-06 | 苏州中荟医疗科技有限公司 | 冲击波发生系统 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009518151A (ja) * | 2005-12-06 | 2009-05-07 | セント・ジュード・メディカル・エイトリアル・フィブリレーション・ディヴィジョン・インコーポレーテッド | 組織切除のための電極結合の評価 |
JP2010507404A (ja) * | 2006-10-18 | 2010-03-11 | ミノウ・メディカル・インコーポレーテッド | 身体組織に望ましい温度作用を誘発するシステム |
JP2010507403A (ja) * | 2006-10-18 | 2010-03-11 | ミノウ・メディカル・インコーポレーテッド | 標的組織の選択的な処置のための調節されたrfエネルギーおよび電気的な組織の特徴付け |
JP2010526557A (ja) * | 2007-02-06 | 2010-08-05 | アラゴン サージカル インク | 電気焼灼方法と装置 |
Family Cites Families (1236)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US164184A (en) | 1875-06-08 | Improvement in vesicular electrodes | ||
US852787A (en) | 1906-04-02 | 1907-05-07 | Arthur G Hoerner | Ironing-board. |
US921973A (en) | 1908-11-17 | 1909-05-18 | L T Gillett | Device for coupling and uncoupling sectional metallic pipe-lines. |
US976733A (en) | 1910-05-25 | 1910-11-22 | Maria A Gilliland | Skimmer. |
US1167014A (en) | 1915-06-25 | 1916-01-04 | William R O'brien | Veterinary surgical instrument. |
US2505358A (en) | 1949-04-20 | 1950-04-25 | Sklar Mfg Co Inc J | Double-cutting biopsy bistoury |
US2701559A (en) | 1951-08-02 | 1955-02-08 | William A Cooper | Apparatus for exfoliating and collecting diagnostic material from inner walls of hollow viscera |
US3108593A (en) | 1961-03-13 | 1963-10-29 | Jacob A Glassman | Surgical extractor |
US3108594A (en) | 1962-08-14 | 1963-10-29 | Jacob A Glassman | Surgical extractor and method of use |
US3540431A (en) | 1968-04-04 | 1970-11-17 | Kazi Mobin Uddin | Collapsible filter for fluid flowing in closed passageway |
US6014590A (en) | 1974-03-04 | 2000-01-11 | Ep Technologies, Inc. | Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions |
US3952747A (en) | 1974-03-28 | 1976-04-27 | Kimmell Jr Garman O | Filter and filter insertion instrument |
US3996938A (en) | 1975-07-10 | 1976-12-14 | Clark Iii William T | Expanding mesh catheter |
US4046150A (en) | 1975-07-17 | 1977-09-06 | American Hospital Supply Corporation | Medical instrument for locating and removing occlusive objects |
US4290427A (en) | 1979-11-26 | 1981-09-22 | Thomas J. Fogarty | Endarterectomy apparatus |
US4402686A (en) | 1981-07-09 | 1983-09-06 | Medel Gonzalo A | Pinched nerve instrument |
US4483341A (en) | 1982-12-09 | 1984-11-20 | Atlantic Richfield Company | Therapeutic hypothermia instrument |
US4784132A (en) | 1983-03-25 | 1988-11-15 | Fox Kenneth R | Method of and apparatus for laser treatment of body lumens |
US4531943A (en) | 1983-08-08 | 1985-07-30 | Angiomedics Corporation | Catheter with soft deformable tip |
EP0152766A1 (en) | 1984-01-24 | 1985-08-28 | Shiley Incorporated | Reduction of an arteriosclerotic lesion by selective absorption of electromagnetic energy in a component thereof |
US4574804A (en) | 1984-02-27 | 1986-03-11 | Board Of Regents, The University Of Texas System | Optic nerve clamp |
US4682596A (en) | 1984-05-22 | 1987-07-28 | Cordis Corporation | Electrosurgical catheter and method for vascular applications |
US4587975A (en) | 1984-07-02 | 1986-05-13 | Cardiac Pacemakers, Inc. | Dimension sensitive angioplasty catheter |
US5162217A (en) | 1984-08-27 | 1992-11-10 | Bio-Technology General Corp. | Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda PL promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof |
US6030611A (en) | 1984-08-27 | 2000-02-29 | Bio-Technology General Corp. | Therapeutic SOD compositions and uses thereof |
US5143836A (en) | 1984-08-27 | 1992-09-01 | Bio-Technology General Corp. | Plasmids for expression of human superoxide dismutase (SOD) analogs containing lambda pl promoter with engineered restriction site for substituting ribosomal binding sites and methods of use thereof |
US4649936A (en) | 1984-10-11 | 1987-03-17 | Case Western Reserve University | Asymmetric single electrode cuff for generation of unidirectionally propagating action potentials for collision blocking |
US4799479A (en) | 1984-10-24 | 1989-01-24 | The Beth Israel Hospital Association | Method and apparatus for angioplasty |
US20020045811A1 (en) | 1985-03-22 | 2002-04-18 | Carter Kittrell | Laser ablation process and apparatus |
US5693043A (en) | 1985-03-22 | 1997-12-02 | Massachusetts Institute Of Technology | Catheter for laser angiosurgery |
US5034010A (en) | 1985-03-22 | 1991-07-23 | Massachusetts Institute Of Technology | Optical shield for a laser catheter |
US5318024A (en) | 1985-03-22 | 1994-06-07 | Massachusetts Institute Of Technology | Laser endoscope for spectroscopic imaging |
US4862886A (en) | 1985-05-08 | 1989-09-05 | Summit Technology Inc. | Laser angioplasty |
US4709698A (en) | 1986-05-14 | 1987-12-01 | Thomas J. Fogarty | Heatable dilation catheter |
GB8622797D0 (en) | 1986-09-22 | 1986-10-29 | Allied Colloids Ltd | Polymeric particles |
US4784162A (en) | 1986-09-23 | 1988-11-15 | Advanced Medical Technologies | Portable, multi-channel, physiological data monitoring system |
US5231995A (en) | 1986-11-14 | 1993-08-03 | Desai Jawahar M | Method for catheter mapping and ablation |
US4785806A (en) | 1987-01-08 | 1988-11-22 | Yale University | Laser ablation process and apparatus |
US4790310A (en) | 1987-02-04 | 1988-12-13 | Robert Ginsburg | Laser catheter having wide angle sweep |
US4765331A (en) | 1987-02-10 | 1988-08-23 | Circon Corporation | Electrosurgical device with treatment arc of less than 360 degrees |
US4823791A (en) | 1987-05-08 | 1989-04-25 | Circon Acmi Division Of Circon Corporation | Electrosurgical probe apparatus |
US4770653A (en) | 1987-06-25 | 1988-09-13 | Medilase, Inc. | Laser angioplasty |
US4938766A (en) | 1987-08-28 | 1990-07-03 | Jarvik Robert K | Prosthetic compliance devices |
US5154705A (en) | 1987-09-30 | 1992-10-13 | Lake Region Manufacturing Co., Inc. | Hollow lumen cable apparatus |
US4788975B1 (en) | 1987-11-05 | 1999-03-02 | Trimedyne Inc | Control system and method for improved laser angioplasty |
US4887605A (en) | 1988-02-18 | 1989-12-19 | Angelsen Bjorn A J | Laser catheter delivery system for controlled atheroma ablation combining laser angioplasty and intra-arterial ultrasonic imagining |
US4890623A (en) | 1988-03-14 | 1990-01-02 | C. R. Bard, Inc. | Biopotential sensing device and method for making |
US5372138A (en) | 1988-03-21 | 1994-12-13 | Boston Scientific Corporation | Acousting imaging catheters and the like |
US5178620A (en) | 1988-06-10 | 1993-01-12 | Advanced Angioplasty Products, Inc. | Thermal dilatation catheter and method |
US4830003A (en) | 1988-06-17 | 1989-05-16 | Wolff Rodney G | Compressive stent and delivery system |
EP0649637A1 (en) | 1988-08-24 | 1995-04-26 | SLEPIAN, Marvin J. | Material for endoluminal paving and sealing |
US4920979A (en) | 1988-10-12 | 1990-05-01 | Huntington Medical Research Institute | Bidirectional helical electrode for nerve stimulation |
US6066130A (en) | 1988-10-24 | 2000-05-23 | The General Hospital Corporation | Delivering laser energy |
US4955377A (en) | 1988-10-28 | 1990-09-11 | Lennox Charles D | Device and method for heating tissue in a patient's body |
US5129396A (en) | 1988-11-10 | 1992-07-14 | Arye Rosen | Microwave aided balloon angioplasty with lumen measurement |
US5419323A (en) | 1988-12-21 | 1995-05-30 | Massachusetts Institute Of Technology | Method for laser induced fluorescence of tissue |
US5697369A (en) | 1988-12-22 | 1997-12-16 | Biofield Corp. | Method and apparatus for disease, injury and bodily condition screening or sensing |
WO1990007303A1 (en) | 1989-01-06 | 1990-07-12 | Angioplasty Systems, Inc. | Electrosurgical catheter for resolving atherosclerotic plaque |
US5749914A (en) | 1989-01-06 | 1998-05-12 | Advanced Coronary Intervention | Catheter for obstructed stent |
US5779698A (en) | 1989-01-18 | 1998-07-14 | Applied Medical Resources Corporation | Angioplasty catheter system and method for making same |
US5052402A (en) | 1989-01-31 | 1991-10-01 | C.R. Bard, Inc. | Disposable biopsy forceps |
US5453091A (en) | 1989-03-17 | 1995-09-26 | Merit Medical Systems, Inc. | RF transmission module for wirelessly transmitting balloon catheter data in a syringe inflation system |
US5125928A (en) | 1989-04-13 | 1992-06-30 | Everest Medical Corporation | Ablation catheter with selectively deployable electrodes |
US5098431A (en) | 1989-04-13 | 1992-03-24 | Everest Medical Corporation | RF ablation catheter |
US4976711A (en) | 1989-04-13 | 1990-12-11 | Everest Medical Corporation | Ablation catheter with selectively deployable electrodes |
US5211651A (en) | 1989-08-18 | 1993-05-18 | Evi Corporation | Catheter atherotome |
JP3036835B2 (ja) | 1989-08-18 | 2000-04-24 | イーブイアイ コーポレイション | カテーテルアテロトーム |
US5156610A (en) | 1989-08-18 | 1992-10-20 | Evi Corporation | Catheter atherotome |
US5282484A (en) | 1989-08-18 | 1994-02-01 | Endovascular Instruments, Inc. | Method for performing a partial atherectomy |
US5071424A (en) | 1989-08-18 | 1991-12-10 | Evi Corporation | Catheter atherotome |
US5622188A (en) | 1989-08-18 | 1997-04-22 | Endovascular Instruments, Inc. | Method of restoring reduced or absent blood flow capacity in an artery |
WO1991003207A1 (en) | 1989-09-08 | 1991-03-21 | Boston Scientific Corporation | Physiologic low stress angioplasty |
US5109859A (en) | 1989-10-04 | 1992-05-05 | Beth Israel Hospital Association | Ultrasound guided laser angioplasty |
US5344395A (en) | 1989-11-13 | 1994-09-06 | Scimed Life Systems, Inc. | Apparatus for intravascular cavitation or delivery of low frequency mechanical energy |
US5290306A (en) | 1989-11-29 | 1994-03-01 | Cordis Corporation | Puncture resistant balloon catheter |
US5074871A (en) | 1989-12-07 | 1991-12-24 | Evi Corporation | Catheter atherotome |
US5178625A (en) | 1989-12-07 | 1993-01-12 | Evi Corporation | Catheter atherotome |
US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
US5158564A (en) | 1990-02-14 | 1992-10-27 | Angiomed Ag | Atherectomy apparatus |
US5084006A (en) | 1990-03-30 | 1992-01-28 | Alza Corporation | Iontopheretic delivery device |
US5098429A (en) | 1990-04-17 | 1992-03-24 | Mmtc, Inc. | Angioplastic technique employing an inductively-heated ferrite material |
US5236413B1 (en) | 1990-05-07 | 1996-06-18 | Andrew J Feiring | Method and apparatus for inducing the permeation of medication into internal tissue |
US5190540A (en) | 1990-06-08 | 1993-03-02 | Cardiovascular & Interventional Research Consultants, Inc. | Thermal balloon angioplasty |
DE69110467T2 (de) | 1990-06-15 | 1996-02-01 | Cortrak Medical Inc | Vorrichtung zur abgabe von medikamenten. |
US5053033A (en) | 1990-10-10 | 1991-10-01 | Boston Advanced Technologies, Inc. | Inhibition of restenosis by ultraviolet radiation |
US5304171A (en) | 1990-10-18 | 1994-04-19 | Gregory Kenton W | Catheter devices and methods for delivering |
US5139496A (en) | 1990-12-20 | 1992-08-18 | Hed Aharon Z | Ultrasonic freeze ablation catheters and probes |
US6524274B1 (en) | 1990-12-28 | 2003-02-25 | Scimed Life Systems, Inc. | Triggered release hydrogel drug delivery system |
US5170802A (en) | 1991-01-07 | 1992-12-15 | Medtronic, Inc. | Implantable electrode for location within a blood vessel |
US5304115A (en) | 1991-01-11 | 1994-04-19 | Baxter International Inc. | Ultrasonic angioplasty device incorporating improved transmission member and ablation probe |
US5312328A (en) | 1991-01-11 | 1994-05-17 | Baxter International Inc. | Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels |
US5368558A (en) | 1991-01-11 | 1994-11-29 | Baxter International Inc. | Ultrasonic ablation catheter device having endoscopic component and method of using same |
US5916192A (en) | 1991-01-11 | 1999-06-29 | Advanced Cardiovascular Systems, Inc. | Ultrasonic angioplasty-atherectomy catheter and method of use |
US5957882A (en) | 1991-01-11 | 1999-09-28 | Advanced Cardiovascular Systems, Inc. | Ultrasound devices for ablating and removing obstructive matter from anatomical passageways and blood vessels |
US5997497A (en) | 1991-01-11 | 1999-12-07 | Advanced Cardiovascular Systems | Ultrasound catheter having integrated drug delivery system and methods of using same |
US5324255A (en) | 1991-01-11 | 1994-06-28 | Baxter International Inc. | Angioplasty and ablative devices having onboard ultrasound components and devices and methods for utilizing ultrasound to treat or prevent vasopasm |
US5542917A (en) | 1991-01-11 | 1996-08-06 | Baxter International, Inc. | Ultrasound delivery catheters incorporating improved distal tip construction |
US5368557A (en) | 1991-01-11 | 1994-11-29 | Baxter International Inc. | Ultrasonic ablation catheter device having multiple ultrasound transmission members |
US5267954A (en) | 1991-01-11 | 1993-12-07 | Baxter International Inc. | Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels |
US5447509A (en) | 1991-01-11 | 1995-09-05 | Baxter International Inc. | Ultrasound catheter system having modulated output with feedback control |
US5380274A (en) | 1991-01-11 | 1995-01-10 | Baxter International Inc. | Ultrasound transmission member having improved longitudinal transmission properties |
US5405318A (en) | 1992-05-05 | 1995-04-11 | Baxter International Inc. | Ultra-sound catheter for removing obstructions from tubular anatomical structures such as blood vessels |
AU660444B2 (en) | 1991-02-15 | 1995-06-29 | Ingemar H. Lundquist | Torquable catheter and method |
US5234407A (en) | 1991-03-06 | 1993-08-10 | Baxter International Inc. | Method and device for exchanging cardiovascular guide catheter while a previously inserted angioplasty guide wire remains in place |
US5454788A (en) | 1991-04-24 | 1995-10-03 | Baxter International Inc. | Exchangeable integrated-wire balloon catheter |
US5251634A (en) | 1991-05-03 | 1993-10-12 | Cyberonics, Inc. | Helical nerve electrode |
US6309379B1 (en) | 1991-05-23 | 2001-10-30 | Lloyd K. Willard | Sheath for selective delivery of multiple intravascular devices and methods of use thereof |
US5270654A (en) | 1991-07-05 | 1993-12-14 | Feinberg David A | Ultra-fast multi-section MRI using gradient and spin echo (grase) imaging |
US5383917A (en) | 1991-07-05 | 1995-01-24 | Jawahar M. Desai | Device and method for multi-phase radio-frequency ablation |
JPH0596012A (ja) | 1991-10-07 | 1993-04-20 | Olympus Optical Co Ltd | 温熱治療装置 |
US5697909A (en) | 1992-01-07 | 1997-12-16 | Arthrocare Corporation | Methods and apparatus for surgical cutting |
JP2505709B2 (ja) | 1991-11-04 | 1996-06-12 | バクスター インターナショナル インコーポレーテッド | ガイドワイヤ進入式超音波切除装置 |
US5906614A (en) | 1991-11-08 | 1999-05-25 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using predicted temperature for monitoring and control |
EP0566725B1 (en) | 1991-11-08 | 2003-06-04 | Boston Scientific Limited | Ablation electrode with insulated temperature sensing elements |
US5383874A (en) | 1991-11-08 | 1995-01-24 | Ep Technologies, Inc. | Systems for identifying catheters and monitoring their use |
US5498261A (en) | 1991-12-20 | 1996-03-12 | Advanced Cardiovascular Systems, Inc. | Thermal angioplasty system |
ATE144124T1 (de) | 1991-12-20 | 1996-11-15 | Technomed Medical Systems | Schallwellen aussendende,thermische effekte und kavitationseffekte erzeugende vorrichtung fur die ultraschalltherapie |
US5301683A (en) | 1991-12-23 | 1994-04-12 | Durkan John A | Diagnosing carpal tunnel syndrome |
US5522873A (en) | 1991-12-26 | 1996-06-04 | Webster Laboratories, Inc. | Catheter having electrode with annular recess and method of using same |
US6179824B1 (en) | 1993-05-10 | 2001-01-30 | Arthrocare Corporation | System and methods for electrosurgical restenosis of body lumens |
US5419767A (en) | 1992-01-07 | 1995-05-30 | Thapliyal And Eggers Partners | Methods and apparatus for advancing catheters through severely occluded body lumens |
US5681282A (en) | 1992-01-07 | 1997-10-28 | Arthrocare Corporation | Methods and apparatus for ablation of luminal tissues |
US5509411A (en) | 1993-01-29 | 1996-04-23 | Cardima, Inc. | Intravascular sensing device |
US5242441A (en) | 1992-02-24 | 1993-09-07 | Boaz Avitall | Deflectable catheter with rotatable tip electrode |
US5263493A (en) | 1992-02-24 | 1993-11-23 | Boaz Avitall | Deflectable loop electrode array mapping and ablation catheter for cardiac chambers |
US5330518A (en) | 1992-03-06 | 1994-07-19 | Urologix, Inc. | Method for treating interstitial tissue associated with microwave thermal therapy |
US5436566A (en) * | 1992-03-17 | 1995-07-25 | Conmed Corporation | Leakage capacitance compensating current sensor for current supplied to medical device loads |
US5306250A (en) | 1992-04-02 | 1994-04-26 | Indiana University Foundation | Method and apparatus for intravascular drug delivery |
US5573533A (en) | 1992-04-10 | 1996-11-12 | Medtronic Cardiorhythm | Method and system for radiofrequency ablation of cardiac tissue |
US5540681A (en) | 1992-04-10 | 1996-07-30 | Medtronic Cardiorhythm | Method and system for radiofrequency ablation of tissue |
US5314466A (en) | 1992-04-13 | 1994-05-24 | Ep Technologies, Inc. | Articulated unidirectional microwave antenna systems for cardiac ablation |
US5300068A (en) | 1992-04-21 | 1994-04-05 | St. Jude Medical, Inc. | Electrosurgical apparatus |
USRE40863E1 (en) | 1992-04-23 | 2009-07-21 | Boston Scientific Scimed, Inc. | Apparatus and method for sealing vascular punctures |
US6063085A (en) | 1992-04-23 | 2000-05-16 | Scimed Life Systems, Inc. | Apparatus and method for sealing vascular punctures |
US5810810A (en) | 1992-04-23 | 1998-09-22 | Scimed Life Systems, Inc. | Apparatus and method for sealing vascular punctures |
JPH07506991A (ja) | 1992-04-23 | 1995-08-03 | シメッド ライフ システムズ インコーポレイテッド | 血管穿刺を密封するための装置及び方法 |
US5277201A (en) | 1992-05-01 | 1994-01-11 | Vesta Medical, Inc. | Endometrial ablation apparatus and method |
US5443470A (en) | 1992-05-01 | 1995-08-22 | Vesta Medical, Inc. | Method and apparatus for endometrial ablation |
US5295484A (en) | 1992-05-19 | 1994-03-22 | Arizona Board Of Regents For And On Behalf Of The University Of Arizona | Apparatus and method for intra-cardiac ablation of arrhythmias |
US5255679A (en) | 1992-06-02 | 1993-10-26 | Cardiac Pathways Corporation | Endocardial catheter for mapping and/or ablation with an expandable basket structure having means for providing selective reinforcement and pressure sensing mechanism for use therewith, and method |
US5478351A (en) | 1992-06-24 | 1995-12-26 | Microsurge, Inc. | Endoscopic surgical tool with handle and detachable tool assembly |
ATE190513T1 (de) | 1992-06-26 | 2000-04-15 | Schneider Usa Inc | Katheter mit ausdehnbarer maschendrahtspitze |
US5382228A (en) | 1992-07-09 | 1995-01-17 | Baxter International Inc. | Method and device for connecting ultrasound transmission member (S) to an ultrasound generating device |
US5365172A (en) | 1992-08-07 | 1994-11-15 | Brigham And Women's Hospital | Methods and apparatus for MRI |
US5297564A (en) | 1992-08-27 | 1994-03-29 | Love Jack W | Catheter technique for creation of an aortico-pulmonary shunt |
US5401272A (en) | 1992-09-25 | 1995-03-28 | Envision Surgical Systems, Inc. | Multimodality probe with extendable bipolar electrodes |
US5333614A (en) | 1992-09-28 | 1994-08-02 | Feiring Andrew J | Measurement of absolute vascular flow |
US5471982A (en) | 1992-09-29 | 1995-12-05 | Ep Technologies, Inc. | Cardiac mapping and ablation systems |
US6086581A (en) | 1992-09-29 | 2000-07-11 | Ep Technologies, Inc. | Large surface cardiac ablation catheter that assumes a low profile during introduction into the heart |
WO1994007446A1 (en) | 1992-10-05 | 1994-04-14 | Boston Scientific Corporation | Device and method for heating tissue |
CA2107741C (en) | 1992-10-07 | 2000-06-27 | Peter T. Keith | Ablation devices and methods of use |
US5687737A (en) | 1992-10-09 | 1997-11-18 | Washington University | Computerized three-dimensional cardiac mapping with interactive visual displays |
US6398782B1 (en) | 1992-10-13 | 2002-06-04 | Edwards Lifesciences Corporation | Bipolar vascular sealing apparatus and methods |
US5432876C1 (en) | 1992-10-19 | 2002-05-21 | Minnesota Mining & Mfg | Illumination devices and optical fibres for use therein |
US5634901A (en) | 1992-11-02 | 1997-06-03 | Localmed, Inc. | Method of using a catheter sleeve |
US5643297A (en) | 1992-11-09 | 1997-07-01 | Endovascular Instruments, Inc. | Intra-artery obstruction clearing apparatus and methods |
US5807306A (en) | 1992-11-09 | 1998-09-15 | Cortrak Medical, Inc. | Polymer matrix drug delivery apparatus |
US5571122A (en) | 1992-11-09 | 1996-11-05 | Endovascular Instruments, Inc. | Unitary removal of plaque |
US6923805B1 (en) | 1992-11-13 | 2005-08-02 | Scimed Life Systems, Inc. | Electrophysiology energy treatment devices and methods of use |
DE4338758C2 (de) | 1992-11-13 | 2001-08-09 | Scimed Life Systems Inc | Katheteranordnung |
US6068653A (en) | 1992-11-13 | 2000-05-30 | Scimed Life Systems, Inc. | Electrophysiology catheter device |
WO1994010922A1 (en) | 1992-11-13 | 1994-05-26 | Ep Technologies, Inc. | Cardial ablation systems using temperature monitoring |
US5676693A (en) | 1992-11-13 | 1997-10-14 | Scimed Life Systems, Inc. | Electrophysiology device |
US5545161A (en) | 1992-12-01 | 1996-08-13 | Cardiac Pathways Corporation | Catheter for RF ablation having cooled electrode with electrically insulated sleeve |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
DE69417465T2 (de) | 1993-02-05 | 1999-07-22 | Joe W And Dorothy Dorsett Brow | Ultraschallballonkatheter für Angioplastik |
US5512051A (en) | 1993-02-16 | 1996-04-30 | Boston Scientific Corporation | Slip-layered catheter balloon |
US6346074B1 (en) | 1993-02-22 | 2002-02-12 | Heartport, Inc. | Devices for less invasive intracardiac interventions |
US6161543A (en) | 1993-02-22 | 2000-12-19 | Epicor, Inc. | Methods of epicardial ablation for creating a lesion around the pulmonary veins |
US5797960A (en) | 1993-02-22 | 1998-08-25 | Stevens; John H. | Method and apparatus for thoracoscopic intracardiac procedures |
US5403311A (en) | 1993-03-29 | 1995-04-04 | Boston Scientific Corporation | Electro-coagulation and ablation and other electrotherapeutic treatments of body tissue |
US6915806B2 (en) | 1993-05-10 | 2005-07-12 | Arthrocare Corporation | Method for harvesting graft vessel |
US5405346A (en) | 1993-05-14 | 1995-04-11 | Fidus Medical Technology Corporation | Tunable microwave ablation catheter |
US5364392A (en) | 1993-05-14 | 1994-11-15 | Fidus Medical Technology Corporation | Microwave ablation catheter system with impedance matching tuner and method |
US5693082A (en) | 1993-05-14 | 1997-12-02 | Fidus Medical Technology Corporation | Tunable microwave ablation catheter system and method |
US5860974A (en) | 1993-07-01 | 1999-01-19 | Boston Scientific Corporation | Heart ablation catheter with expandable electrode and method of coupling energy to an electrode on a catheter shaft |
JP3898754B2 (ja) | 1993-07-01 | 2007-03-28 | ボストン サイエンティフィック リミテッド | 像形成、電位検出型及び切除カテーテル |
US5630837A (en) | 1993-07-01 | 1997-05-20 | Boston Scientific Corporation | Acoustic ablation |
US5584831A (en) | 1993-07-09 | 1996-12-17 | September 28, Inc. | Spinal fixation device and method |
US5409000A (en) | 1993-09-14 | 1995-04-25 | Cardiac Pathways Corporation | Endocardial mapping and ablation system utilizing separately controlled steerable ablation catheter with ultrasonic imaging capabilities and method |
US5843124A (en) | 1993-09-28 | 1998-12-01 | Hemodynamics, Inc. | Surface opening adhesive sealer |
US5417672A (en) | 1993-10-04 | 1995-05-23 | Baxter International Inc. | Connector for coupling an ultrasound transducer to an ultrasound catheter |
US5427118A (en) | 1993-10-04 | 1995-06-27 | Baxter International Inc. | Ultrasonic guidewire |
US5496312A (en) | 1993-10-07 | 1996-03-05 | Valleylab Inc. | Impedance and temperature generator control |
US5840076A (en) | 1996-04-12 | 1998-11-24 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using electrode structures with distally oriented porous regions |
US5797903A (en) | 1996-04-12 | 1998-08-25 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using porous electrode structures with electrically conductive surfaces |
US5991650A (en) | 1993-10-15 | 1999-11-23 | Ep Technologies, Inc. | Surface coatings for catheters, direct contacting diagnostic and therapeutic devices |
WO1995010225A1 (en) | 1993-10-15 | 1995-04-20 | Ep Technologies, Inc. | Multiple electrode element for mapping and ablating |
US5599346A (en) | 1993-11-08 | 1997-02-04 | Zomed International, Inc. | RF treatment system |
JP3400835B2 (ja) | 1993-12-20 | 2003-04-28 | テルモ株式会社 | 副伝導路検出装置 |
US5441498A (en) | 1994-02-16 | 1995-08-15 | Envision Surgical Systems, Inc. | Method of using a multimodality probe with extendable bipolar electrodes |
US5588962A (en) | 1994-03-29 | 1996-12-31 | Boston Scientific Corporation | Drug treatment of diseased sites deep within the body |
US5505201A (en) | 1994-04-20 | 1996-04-09 | Case Western Reserve University | Implantable helical spiral cuff electrode |
US5451207A (en) | 1994-04-25 | 1995-09-19 | The Regents Of The University Of California | Method of coronary plaque removal with bypass and perfusion |
US5715819A (en) | 1994-05-26 | 1998-02-10 | The Carolinas Heart Institute | Microwave tomographic spectroscopy system and method |
US5573531A (en) | 1994-06-20 | 1996-11-12 | Gregory; Kenton W. | Fluid core laser angioscope |
US6056744A (en) | 1994-06-24 | 2000-05-02 | Conway Stuart Medical, Inc. | Sphincter treatment apparatus |
US5505730A (en) | 1994-06-24 | 1996-04-09 | Stuart D. Edwards | Thin layer ablation apparatus |
US6405732B1 (en) | 1994-06-24 | 2002-06-18 | Curon Medical, Inc. | Method to treat gastric reflux via the detection and ablation of gastro-esophageal nerves and receptors |
WO1996000528A1 (en) | 1994-06-27 | 1996-01-11 | Ep Technologies, Inc. | Non-linear control systems and methods for heating and ablating body tissue |
JP3564141B2 (ja) | 1994-06-27 | 2004-09-08 | ボストン サイエンティフィック リミテッド | 複数の温度感知要素を使用して組織のアブレーションを制御するためのシステム |
US5735846A (en) | 1994-06-27 | 1998-04-07 | Ep Technologies, Inc. | Systems and methods for ablating body tissue using predicted maximum tissue temperature |
CA2194061C (en) | 1994-06-27 | 2006-04-11 | David K. Swanson | Systems and methods for sensing temperature within the body |
AU2970495A (en) | 1994-07-19 | 1996-02-16 | Hologram Technology International, Inc. | Image recording medium and method of making same |
US5810802A (en) | 1994-08-08 | 1998-09-22 | E.P. Technologies, Inc. | Systems and methods for controlling tissue ablation using multiple temperature sensing elements |
US5967976A (en) | 1994-08-19 | 1999-10-19 | Novoste Corporation | Apparatus and methods for procedures related to the electrophysiology of the heart |
US5531520A (en) | 1994-09-01 | 1996-07-02 | Massachusetts Institute Of Technology | System and method of registration of three-dimensional data sets including anatomical body data |
US8025661B2 (en) | 1994-09-09 | 2011-09-27 | Cardiofocus, Inc. | Coaxial catheter instruments for ablation with radiant energy |
US6572609B1 (en) | 1999-07-14 | 2003-06-03 | Cardiofocus, Inc. | Phototherapeutic waveguide apparatus |
US5647847A (en) | 1994-09-16 | 1997-07-15 | Scimed Life Systems, Inc. | Balloon catheter with improved pressure source |
US5876336A (en) | 1994-10-11 | 1999-03-02 | Ep Technologies, Inc. | Systems and methods for guiding movable electrode elements within multiple-electrode structure |
US5810742A (en) | 1994-10-24 | 1998-09-22 | Transcan Research & Development Co., Ltd. | Tissue characterization based on impedance images and on impedance measurements |
US5817144A (en) | 1994-10-25 | 1998-10-06 | Latis, Inc. | Method for contemporaneous application OF laser energy and localized pharmacologic therapy |
US5571151A (en) | 1994-10-25 | 1996-11-05 | Gregory; Kenton W. | Method for contemporaneous application of laser energy and localized pharmacologic therapy |
US6689086B1 (en) | 1994-10-27 | 2004-02-10 | Advanced Cardiovascular Systems, Inc. | Method of using a catheter for delivery of ultrasonic energy and medicament |
US5643255A (en) | 1994-12-12 | 1997-07-01 | Hicor, Inc. | Steerable catheter with rotatable tip electrode and method of use |
US5665062A (en) | 1995-01-23 | 1997-09-09 | Houser; Russell A. | Atherectomy catheter and RF cutting method |
US5776174A (en) | 1995-01-30 | 1998-07-07 | Illumenex Corporation | Stabilization of vascular lesions by ultraviolet radiation |
FR2729845B1 (fr) | 1995-02-01 | 1997-07-25 | Centre Nat Rech Scient | Catheter d'imagerie echographique endocavitaire |
US6409722B1 (en) | 1998-07-07 | 2002-06-25 | Medtronic, Inc. | Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue |
US5904697A (en) | 1995-02-24 | 1999-05-18 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US5695504A (en) | 1995-02-24 | 1997-12-09 | Heartport, Inc. | Devices and methods for performing a vascular anastomosis |
US6110187A (en) | 1995-02-24 | 2000-08-29 | Heartport, Inc. | Device and method for minimizing heart displacements during a beating heart surgical procedure |
EP0827383B1 (en) | 1995-02-28 | 2007-05-30 | Boston Scientific Corporation | Polymer implements for torque transmission |
US5797849A (en) | 1995-03-28 | 1998-08-25 | Sonometrics Corporation | Method for carrying out a medical procedure using a three-dimensional tracking and imaging system |
US5755753A (en) | 1995-05-05 | 1998-05-26 | Thermage, Inc. | Method for controlled contraction of collagen tissue |
US6425912B1 (en) | 1995-05-05 | 2002-07-30 | Thermage, Inc. | Method and apparatus for modifying skin surface and soft tissue structure |
US6470216B1 (en) | 1995-05-05 | 2002-10-22 | Thermage, Inc. | Method for smoothing contour irregularities of skin surface |
US6241753B1 (en) | 1995-05-05 | 2001-06-05 | Thermage, Inc. | Method for scar collagen formation and contraction |
US5660836A (en) | 1995-05-05 | 1997-08-26 | Knowlton; Edward W. | Method and apparatus for controlled contraction of collagen tissue |
US6251104B1 (en) | 1995-05-10 | 2001-06-26 | Eclipse Surgical Technologies, Inc. | Guiding catheter system for ablating heart tissue |
US5782760A (en) | 1995-05-23 | 1998-07-21 | Cardima, Inc. | Over-the-wire EP catheter |
US6190379B1 (en) | 1995-06-06 | 2001-02-20 | Sun Star Technology, Inc. | Hot tip catheter |
US5666964A (en) | 1995-06-06 | 1997-09-16 | Meilus; Algis A. | Muscle treatment devices |
US6632193B1 (en) | 1995-06-07 | 2003-10-14 | Arthrocare Corporation | Systems and methods for electrosurgical tissue treatment |
US5741248A (en) | 1995-06-07 | 1998-04-21 | Temple University-Of The Commonwealth System Of Higher Education | Fluorochemical liquid augmented cryosurgery |
US6293943B1 (en) | 1995-06-07 | 2001-09-25 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods which predict maximum tissue temperature |
US6837888B2 (en) | 1995-06-07 | 2005-01-04 | Arthrocare Corporation | Electrosurgical probe with movable return electrode and methods related thereto |
US6004319A (en) | 1995-06-23 | 1999-12-21 | Gyrus Medical Limited | Electrosurgical instrument |
US6293942B1 (en) | 1995-06-23 | 2001-09-25 | Gyrus Medical Limited | Electrosurgical generator method |
US5702433A (en) | 1995-06-27 | 1997-12-30 | Arrow International Investment Corp. | Kink-resistant steerable catheter assembly for microwave ablation |
US8241217B2 (en) | 1995-06-29 | 2012-08-14 | Teratech Corporation | Portable ultrasound imaging data |
WO1997001988A1 (en) | 1995-06-30 | 1997-01-23 | Boston Scientific Corporation | Ultrasound imaging catheter with a cutting element |
US5693029A (en) | 1995-07-10 | 1997-12-02 | World Medical Manufacturing Corporation | Pro-cell intra-cavity therapeutic agent delivery device |
US5865801A (en) | 1995-07-18 | 1999-02-02 | Houser; Russell A. | Multiple compartmented balloon catheter with external pressure sensing |
US5672174A (en) | 1995-08-15 | 1997-09-30 | Rita Medical Systems, Inc. | Multiple antenna ablation apparatus and method |
US5800484A (en) | 1995-08-15 | 1998-09-01 | Rita Medical Systems, Inc. | Multiple antenna ablation apparatus with expanded electrodes |
US6763261B2 (en) | 1995-09-20 | 2004-07-13 | Board Of Regents, The University Of Texas System | Method and apparatus for detecting vulnerable atherosclerotic plaque |
US6090618A (en) | 1996-10-07 | 2000-07-18 | Arch Development Corporation | DNA constructs and viral vectors comprising a smooth muscle promoter |
AU726713B2 (en) | 1995-10-13 | 2000-11-16 | Transvascular, Inc. | Methods and apparatus for bypassing arterial obstructions and/or performing other transvascular procedures |
AU729466B2 (en) | 1995-10-13 | 2001-02-01 | Transvascular, Inc. | A device, system and method for interstitial transvascular intervention |
US5846245A (en) | 1995-10-20 | 1998-12-08 | New York University | Bone-adjusting device |
US5817092A (en) | 1995-11-09 | 1998-10-06 | Radio Therapeutics Corporation | Apparatus, system and method for delivering radio frequency energy to a treatment site |
US5833593A (en) | 1995-11-09 | 1998-11-10 | United States Surgical Corporation | Flexible source wire for localized internal irradiation of tissue |
US5906623A (en) | 1995-12-11 | 1999-05-25 | Boston Scientific Corporation | Lithotripsy system |
NZ299133A (en) * | 1995-12-11 | 1997-09-22 | Megadyne Med Prod Inc | Electrocautery instrument; details relating to an insulation covering overlaid by a conducting layer, the layers being on a metallic shaft component of the instrument |
US6350276B1 (en) | 1996-01-05 | 2002-02-26 | Thermage, Inc. | Tissue remodeling apparatus containing cooling fluid |
US5836874A (en) | 1996-04-08 | 1998-11-17 | Ep Technologies, Inc. | Multi-function electrode structures for electrically analyzing and heating body tissue |
US5891135A (en) | 1996-01-19 | 1999-04-06 | Ep Technologies, Inc. | Stem elements for securing tubing and electrical wires to expandable-collapsible electrode structures |
US6071278A (en) | 1996-02-28 | 2000-06-06 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using porous electrode structures with specified electrical resistivities |
US5868736A (en) | 1996-04-12 | 1999-02-09 | Ep Technologies, Inc. | Systems and methods to control tissue heating or ablation with porous electrode structures |
US6475213B1 (en) | 1996-01-19 | 2002-11-05 | Ep Technologies, Inc. | Method of ablating body tissue |
US5961513A (en) | 1996-01-19 | 1999-10-05 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using porous electrode structures |
US5853411A (en) | 1996-01-19 | 1998-12-29 | Ep Technologies, Inc. | Enhanced electrical connections for electrode structures |
US5846239A (en) | 1996-04-12 | 1998-12-08 | Ep Technologies, Inc. | Tissue heating and ablation systems and methods using segmented porous electrode structures |
US5871483A (en) | 1996-01-19 | 1999-02-16 | Ep Technologies, Inc. | Folding electrode structures |
US5830213A (en) | 1996-04-12 | 1998-11-03 | Ep Technologies, Inc. | Systems for heating and ablating tissue using multifunctional electrode structures |
US5846238A (en) | 1996-01-19 | 1998-12-08 | Ep Technologies, Inc. | Expandable-collapsible electrode structures with distal end steering or manipulation |
US5879348A (en) | 1996-04-12 | 1999-03-09 | Ep Technologies, Inc. | Electrode structures formed from flexible, porous, or woven materials |
US5925038A (en) | 1996-01-19 | 1999-07-20 | Ep Technologies, Inc. | Expandable-collapsible electrode structures for capacitive coupling to tissue |
US5891136A (en) | 1996-01-19 | 1999-04-06 | Ep Technologies, Inc. | Expandable-collapsible mesh electrode structures |
WO1997025919A1 (en) | 1996-01-19 | 1997-07-24 | Ep Technologies, Inc. | Systems and methods for heating and ablating tissue using multifunctional electrode structures |
DE69724255T2 (de) | 1996-02-02 | 2004-06-03 | Transvascular, Inc., Menlo Park | System für interstitielle transvaskuläre chirurgische eingriffe |
SE9600389D0 (sv) * | 1996-02-02 | 1996-02-02 | Pacesetter Ab | Medical device used to stimulate tissue |
US6436056B1 (en) | 1996-02-28 | 2002-08-20 | Boston Scientific Corporation | Polymeric implements for torque transmission |
US6036687A (en) | 1996-03-05 | 2000-03-14 | Vnus Medical Technologies, Inc. | Method and apparatus for treating venous insufficiency |
JP4060887B2 (ja) | 1996-03-05 | 2008-03-12 | ヴィナス メディカル テクノロジーズ インコーポレイテッド | 組織を加熱するための脈管カテーテル利用システム |
US6152899A (en) | 1996-03-05 | 2000-11-28 | Vnus Medical Technologies, Inc. | Expandable catheter having improved electrode design, and method for applying energy |
US6033397A (en) | 1996-03-05 | 2000-03-07 | Vnus Medical Technologies, Inc. | Method and apparatus for treating esophageal varices |
US6139527A (en) | 1996-03-05 | 2000-10-31 | Vnus Medical Technologies, Inc. | Method and apparatus for treating hemorrhoids |
US5843016A (en) | 1996-03-18 | 1998-12-01 | Physion S.R.L. | Electromotive drug administration for treatment of acute urinary outflow obstruction |
US5690681A (en) | 1996-03-29 | 1997-11-25 | Purdue Research Foundation | Method and apparatus using vagal stimulation for control of ventricular rate during atrial fibrillation |
US5769880A (en) | 1996-04-12 | 1998-06-23 | Novacept | Moisture transport system for contact electrocoagulation |
US6813520B2 (en) | 1996-04-12 | 2004-11-02 | Novacept | Method for ablating and/or coagulating tissue using moisture transport |
US7604633B2 (en) | 1996-04-12 | 2009-10-20 | Cytyc Corporation | Moisture transport system for contact electrocoagulation |
US6673040B1 (en) | 1996-04-16 | 2004-01-06 | Cardeon Corporation | System and methods for catheter procedures with circulatory support in high risk patients |
US5904709A (en) | 1996-04-17 | 1999-05-18 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Microwave treatment for cardiac arrhythmias |
US20020045890A1 (en) | 1996-04-24 | 2002-04-18 | The Regents Of The University O F California | Opto-acoustic thrombolysis |
US6022309A (en) | 1996-04-24 | 2000-02-08 | The Regents Of The University Of California | Opto-acoustic thrombolysis |
US6898454B2 (en) | 1996-04-25 | 2005-05-24 | The Johns Hopkins University | Systems and methods for evaluating the urethra and the periurethral tissues |
AUPN957296A0 (en) | 1996-04-30 | 1996-05-23 | Cardiac Crc Nominees Pty Limited | A system for simultaneous unipolar multi-electrode ablation |
US7022105B1 (en) | 1996-05-06 | 2006-04-04 | Novasys Medical Inc. | Treatment of tissue in sphincters, sinuses and orifices |
US6066139A (en) | 1996-05-14 | 2000-05-23 | Sherwood Services Ag | Apparatus and method for sterilization and embolization |
GB9612993D0 (en) | 1996-06-20 | 1996-08-21 | Gyrus Medical Ltd | Electrosurgical instrument |
US5882346A (en) | 1996-07-15 | 1999-03-16 | Cardiac Pathways Corporation | Shapable catheter using exchangeable core and method of use |
US5662671A (en) | 1996-07-17 | 1997-09-02 | Embol-X, Inc. | Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries |
US5832228A (en) | 1996-07-30 | 1998-11-03 | Itt Industries, Inc. | System and method for providing multi-level security in computer devices utilized with non-secure networks |
US5755682A (en) | 1996-08-13 | 1998-05-26 | Heartstent Corporation | Method and apparatus for performing coronary artery bypass surgery |
US6684098B2 (en) | 1996-08-16 | 2004-01-27 | Brigham And Women's Hospital, Inc. | Versatile stereotactic device and methods of use |
US7203537B2 (en) | 1996-08-19 | 2007-04-10 | Mr3 Medical, Llc | System and method for breaking reentry circuits by cooling cardiac tissue |
US5800494A (en) | 1996-08-20 | 1998-09-01 | Fidus Medical Technology Corporation | Microwave ablation catheters having antennas with distal fire capabilities |
US6123679A (en) | 1996-08-29 | 2000-09-26 | Lafaut; Jean-Pierre | Method for extracorporeal shock wave lithotripsy by applying an acoustic shock wave followed by a limited oscillating acoustic pressure wave train |
US7603166B2 (en) | 1996-09-20 | 2009-10-13 | Board Of Regents University Of Texas System | Method and apparatus for detection of vulnerable atherosclerotic plaque |
US6451044B1 (en) | 1996-09-20 | 2002-09-17 | Board Of Regents, The University Of Texas System | Method and apparatus for heating inflammed tissue |
US5906636A (en) | 1996-09-20 | 1999-05-25 | Texas Heart Institute | Heat treatment of inflamed tissue |
US5954740A (en) | 1996-09-23 | 1999-09-21 | Boston Scientific Corporation | Catheter balloon having raised radial segments |
US5957941A (en) | 1996-09-27 | 1999-09-28 | Boston Scientific Corporation | Catheter system and drive assembly thereof |
US5971975A (en) | 1996-10-09 | 1999-10-26 | Target Therapeutics, Inc. | Guide catheter with enhanced guidewire tracking |
US6464697B1 (en) | 1998-02-19 | 2002-10-15 | Curon Medical, Inc. | Stomach and adjoining tissue regions in the esophagus |
US5931834A (en) | 1996-10-15 | 1999-08-03 | Eclipse Surgical Technologies, Inc. | Method for non-synchronous laser-assisted myocardial revascularization |
US5785702A (en) | 1996-10-15 | 1998-07-28 | Eclipse Surgical Technologies, Inc. | Method for non-synchronous laser-assisted transmyocardial revascularization |
US5810803A (en) | 1996-10-16 | 1998-09-22 | Fidus Medical Technology Corporation | Conformal positioning assembly for microwave ablation catheter |
US5741249A (en) | 1996-10-16 | 1998-04-21 | Fidus Medical Technology Corporation | Anchoring tip assembly for microwave ablation catheter |
US6237605B1 (en) | 1996-10-22 | 2001-05-29 | Epicor, Inc. | Methods of epicardial ablation |
US5848969A (en) | 1996-10-28 | 1998-12-15 | Ep Technologies, Inc. | Systems and methods for visualizing interior tissue regions using expandable imaging structures |
US5904651A (en) | 1996-10-28 | 1999-05-18 | Ep Technologies, Inc. | Systems and methods for visualizing tissue during diagnostic or therapeutic procedures |
US5827268A (en) | 1996-10-30 | 1998-10-27 | Hearten Medical, Inc. | Device for the treatment of patent ductus arteriosus and method of using the device |
US6081749A (en) | 1997-08-13 | 2000-06-27 | Surx, Inc. | Noninvasive devices, methods, and systems for shrinking of tissues |
US6091995A (en) | 1996-11-08 | 2000-07-18 | Surx, Inc. | Devices, methods, and systems for shrinking tissues |
US5875782A (en) | 1996-11-14 | 1999-03-02 | Cardiothoracic Systems, Inc. | Methods and devices for minimally invasive coronary artery revascularization on a beating heart without cardiopulmonary bypass |
WO1998022184A1 (en) | 1996-11-21 | 1998-05-28 | Boston Scientific Corporation | Mucosal ablation using light |
US6159187A (en) | 1996-12-06 | 2000-12-12 | Target Therapeutics, Inc. | Reinforced catheter with a formable distal tip |
US5999678A (en) | 1996-12-27 | 1999-12-07 | Eclipse Surgical Technologies, Inc. | Laser delivery means adapted for drug delivery |
CA2225521C (en) | 1996-12-27 | 2004-04-06 | Eclipse Surgical Technologies, Inc. | Laser assisted drug delivery apparatus |
US5775338A (en) | 1997-01-10 | 1998-07-07 | Scimed Life Systems, Inc. | Heated perfusion balloon for reduction of restenosis |
US8329179B2 (en) | 1997-01-28 | 2012-12-11 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
US7452538B2 (en) | 1997-01-28 | 2008-11-18 | Human Genome Sciences, Inc. | Death domain containing receptor 4 antibodies and methods |
JP4450870B2 (ja) | 1997-01-28 | 2010-04-14 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 死ドメイン含有レセプター4(dr4:死レセプター4)、tnf−レセプタースーパーファミリーのメンバーおよびtrailへの結合 |
AU6657098A (en) | 1997-02-12 | 1998-08-26 | Prolifix Medical, Inc. | Apparatus for removal of material from stents |
US5989284A (en) | 1997-02-18 | 1999-11-23 | Hearten Medical, Inc. | Method and device for soft tissue modification |
US6120516A (en) | 1997-02-28 | 2000-09-19 | Lumend, Inc. | Method for treating vascular occlusion |
US5868735A (en) | 1997-03-06 | 1999-02-09 | Scimed Life Systems, Inc. | Cryoplasty device and method |
US7220257B1 (en) | 2000-07-25 | 2007-05-22 | Scimed Life Systems, Inc. | Cryotreatment device and method |
AU6561898A (en) | 1997-03-17 | 1998-10-12 | Boris Rubinsky | Freezing method for controlled removal of fatty tissue by liposuction |
US5904667A (en) | 1997-03-17 | 1999-05-18 | C.R. Bard, Inc. | Rotatable control mechanism for steerable catheter |
US7425212B1 (en) | 1998-06-10 | 2008-09-16 | Asthmatx, Inc. | Devices for modification of airways by transfer of energy |
US5972026A (en) | 1997-04-07 | 1999-10-26 | Broncus Technologies, Inc. | Bronchial stenter having diametrically adjustable electrodes |
US6488673B1 (en) | 1997-04-07 | 2002-12-03 | Broncus Technologies, Inc. | Method of increasing gas exchange of a lung |
US6524299B1 (en) | 1997-04-09 | 2003-02-25 | Target Therapeutics, Inc. | Flow-directed catheter |
AU744343B2 (en) | 1997-04-11 | 2002-02-21 | Transvascular, Inc. | Methods and apparatus for transmyocardial direct coronary revascularization |
US5827203A (en) | 1997-04-21 | 1998-10-27 | Nita; Henry | Ultrasound system and method for myocardial revascularization |
GB9708268D0 (en) | 1997-04-24 | 1997-06-18 | Gyrus Medical Ltd | An electrosurgical instrument |
US6117128A (en) | 1997-04-30 | 2000-09-12 | Kenton W. Gregory | Energy delivery catheter and method for the use thereof |
US6723063B1 (en) | 1998-06-29 | 2004-04-20 | Ekos Corporation | Sheath for use with an ultrasound element |
US6024740A (en) | 1997-07-08 | 2000-02-15 | The Regents Of The University Of California | Circumferential ablation device assembly |
US5989208A (en) | 1997-05-16 | 1999-11-23 | Nita; Henry | Therapeutic ultrasound system |
US6217576B1 (en) | 1997-05-19 | 2001-04-17 | Irvine Biomedical Inc. | Catheter probe for treating focal atrial fibrillation in pulmonary veins |
US5895378A (en) | 1997-05-29 | 1999-04-20 | Target Therapeutics, Inc. | Flow-directed catheter having multiple tapers and radio-opaque markers |
US6152912A (en) | 1997-06-10 | 2000-11-28 | Target Therapeutics, Inc. | Optimized high performance spiral-wound vascular catheter |
US5951539A (en) | 1997-06-10 | 1999-09-14 | Target Therpeutics, Inc. | Optimized high performance multiple coil spiral-wound vascular catheter |
AU7141198A (en) | 1997-06-13 | 1998-12-30 | Arthrocare Corporation | Electrosurgical systems and methods for recanalization of occluded body lumens |
US6855143B2 (en) | 1997-06-13 | 2005-02-15 | Arthrocare Corporation | Electrosurgical systems and methods for recanalization of occluded body lumens |
EP0989822A4 (en) | 1997-06-23 | 2004-07-28 | Focus Surgery Inc | ACOUSTIC HEMOSTASIS METHODS AND DEVICES |
WO1999000060A1 (en) | 1997-06-26 | 1999-01-07 | Advanced Coronary Intervention | Electrosurgical catheter for resolving obstructions by radio frequency ablation |
USRE40279E1 (en) | 1997-06-26 | 2008-04-29 | Sherwood Services Ag | Method and system for neural tissue modification |
US6241666B1 (en) | 1997-07-03 | 2001-06-05 | Cardiac Pathways Corp. | Ablation catheter tip with a buffer layer covering the electrode |
US6500174B1 (en) | 1997-07-08 | 2002-12-31 | Atrionix, Inc. | Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member |
US6547788B1 (en) | 1997-07-08 | 2003-04-15 | Atrionx, Inc. | Medical device with sensor cooperating with expandable member |
US6869431B2 (en) | 1997-07-08 | 2005-03-22 | Atrionix, Inc. | Medical device with sensor cooperating with expandable member |
US6117101A (en) | 1997-07-08 | 2000-09-12 | The Regents Of The University Of California | Circumferential ablation device assembly |
US6966908B2 (en) | 1997-07-08 | 2005-11-22 | Atrionix, Inc. | Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall |
US6997925B2 (en) | 1997-07-08 | 2006-02-14 | Atrionx, Inc. | Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall |
US6652515B1 (en) | 1997-07-08 | 2003-11-25 | Atrionix, Inc. | Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall |
US5891138A (en) | 1997-08-11 | 1999-04-06 | Irvine Biomedical, Inc. | Catheter system having parallel electrodes |
ATE326913T1 (de) | 1997-08-13 | 2006-06-15 | Solarant Medical Inc | Nichtinvasive geräte und systeme zum schrumpfen von geweben |
US9023031B2 (en) | 1997-08-13 | 2015-05-05 | Verathon Inc. | Noninvasive devices, methods, and systems for modifying tissues |
US5964757A (en) | 1997-09-05 | 1999-10-12 | Cordis Webster, Inc. | Steerable direct myocardial revascularization catheter |
US6402719B1 (en) | 1997-09-05 | 2002-06-11 | Cordis Webster, Inc. | Steerable DMR catheter with infusion tube |
US6200312B1 (en) | 1997-09-11 | 2001-03-13 | Vnus Medical Technologies, Inc. | Expandable vein ligator catheter having multiple electrode leads |
US6179832B1 (en) | 1997-09-11 | 2001-01-30 | Vnus Medical Technologies, Inc. | Expandable catheter having two sets of electrodes |
US6258084B1 (en) | 1997-09-11 | 2001-07-10 | Vnus Medical Technologies, Inc. | Method for applying energy to biological tissue including the use of tumescent tissue compression |
US6401719B1 (en) | 1997-09-11 | 2002-06-11 | Vnus Medical Technologies, Inc. | Method of ligating hollow anatomical structures |
US5954717A (en) | 1997-09-25 | 1999-09-21 | Radiotherapeutics Corporation | Method and system for heating solid tissue |
US8257725B2 (en) | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
US6007514A (en) | 1997-09-30 | 1999-12-28 | Nita; Henry | Ultrasound system with pathfinding guidewire |
US6238389B1 (en) | 1997-09-30 | 2001-05-29 | Boston Scientific Corporation | Deflectable interstitial ablation device |
US5891114A (en) | 1997-09-30 | 1999-04-06 | Target Therapeutics, Inc. | Soft-tip high performance braided catheter |
US6706010B1 (en) | 1997-10-08 | 2004-03-16 | Kaneka Corporation | Balloon catheter and method of production thereof |
US6231516B1 (en) | 1997-10-14 | 2001-05-15 | Vacusense, Inc. | Endoluminal implant with therapeutic and diagnostic capability |
US5935063A (en) | 1997-10-29 | 1999-08-10 | Irvine Biomedical, Inc. | Electrode catheter system and methods thereof |
US6156046A (en) | 1997-11-07 | 2000-12-05 | Prolifix Medical, Inc. | Methods and systems for treating obstructions in a body lumen |
US6120476A (en) | 1997-12-01 | 2000-09-19 | Cordis Webster, Inc. | Irrigated tip catheter |
US5971979A (en) | 1997-12-02 | 1999-10-26 | Odyssey Technologies, Inc. | Method for cryogenic inhibition of hyperplasia |
CA2318243A1 (en) | 1998-01-12 | 1999-07-15 | Ronald P. Lesser | Technique for using brain heat flow management to treat brain disorders |
AU2114299A (en) | 1998-01-14 | 1999-08-02 | Conway-Stuart Medical, Inc. | Electrosurgical device for sphincter treatment |
EP1047348A1 (en) | 1998-01-14 | 2000-11-02 | Conway-Stuart Medical, Inc. | Lectrosurgical apparatus for treating gatroesophageal reflux disease (gerd) and method |
CA2318771A1 (en) | 1998-01-26 | 1999-07-29 | Scimed Life Systems, Inc. | Catheter assembly with distal end inductive coupler and embedded transmission line |
US6447505B2 (en) | 1998-02-11 | 2002-09-10 | Cosman Company, Inc. | Balloon catheter method for intra-urethral radio-frequency urethral enlargement |
US6517534B1 (en) | 1998-02-11 | 2003-02-11 | Cosman Company, Inc. | Peri-urethral ablation |
US6651670B2 (en) | 1998-02-13 | 2003-11-25 | Ventrica, Inc. | Delivering a conduit into a heart wall to place a coronary vessel in communication with a heart chamber and removing tissue from the vessel or heart wall to facilitate such communication |
US7165551B2 (en) | 1998-02-19 | 2007-01-23 | Curon Medical, Inc. | Apparatus to detect and treat aberrant myoelectric activity |
US6273886B1 (en) | 1998-02-19 | 2001-08-14 | Curon Medical, Inc. | Integrated tissue heating and cooling apparatus |
US6258087B1 (en) | 1998-02-19 | 2001-07-10 | Curon Medical, Inc. | Expandable electrode assemblies for forming lesions to treat dysfunction in sphincters and adjoining tissue regions |
US6142993A (en) | 1998-02-27 | 2000-11-07 | Ep Technologies, Inc. | Collapsible spline structure using a balloon as an expanding actuator |
CA2321671C (en) | 1998-03-02 | 2009-07-14 | Atrionix, Inc. | Tissue ablation system and method for forming long linear lesion |
JP2002505138A (ja) | 1998-03-06 | 2002-02-19 | キューロン メディカル,インコーポレイテッド | 電気外科的に食道括約筋を処置するための器具 |
US6115626A (en) | 1998-03-26 | 2000-09-05 | Scimed Life Systems, Inc. | Systems and methods using annotated images for controlling the use of diagnostic or therapeutic instruments in instruments in interior body regions |
AU3454999A (en) | 1998-03-30 | 1999-10-18 | University Of Virginia Patent Foundation | Flow arrest, double balloon technique for occluding aneurysms or blood vessels |
US6200266B1 (en) | 1998-03-31 | 2001-03-13 | Case Western Reserve University | Method and apparatus for ultrasound imaging using acoustic impedance reconstruction |
US6142991A (en) | 1998-03-31 | 2000-11-07 | Galil Medical, Ltd. | High resolution cryosurgical method and apparatus |
WO1999049908A1 (en) | 1998-03-31 | 1999-10-07 | University Of Cincinnati | Temperature controlled solute delivery system |
US6905494B2 (en) | 1998-03-31 | 2005-06-14 | Innercool Therapies, Inc. | Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection |
US6685732B2 (en) | 1998-03-31 | 2004-02-03 | Innercool Therapies, Inc. | Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing microporous balloon |
US7001378B2 (en) | 1998-03-31 | 2006-02-21 | Innercool Therapies, Inc. | Method and device for performing cooling or cryo-therapies, for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection |
US6666874B2 (en) | 1998-04-10 | 2003-12-23 | Endicor Medical, Inc. | Rotational atherectomy system with serrated cutting tip |
US6219577B1 (en) | 1998-04-14 | 2001-04-17 | Global Vascular Concepts, Inc. | Iontophoresis, electroporation and combination catheters for local drug delivery to arteries and other body tissues |
US20020065542A1 (en) | 1998-04-22 | 2002-05-30 | Ronald G. Lax | Method and apparatus for treating an aneurysm |
US6161047A (en) | 1998-04-30 | 2000-12-12 | Medtronic Inc. | Apparatus and method for expanding a stimulation lead body in situ |
US6050994A (en) | 1998-05-05 | 2000-04-18 | Cardiac Pacemakers, Inc. | RF ablation apparatus and method using controllable duty cycle with alternate phasing |
US6558378B2 (en) | 1998-05-05 | 2003-05-06 | Cardiac Pacemakers, Inc. | RF ablation system and method having automatic temperature control |
US6508815B1 (en) | 1998-05-08 | 2003-01-21 | Novacept | Radio-frequency generator for powering an ablation device |
US6066096A (en) | 1998-05-08 | 2000-05-23 | Duke University | Imaging probes and catheters for volumetric intraluminal ultrasound imaging and related systems |
US6022901A (en) | 1998-05-13 | 2000-02-08 | Pharmascience Inc. | Administration of resveratrol to prevent or treat restenosis following coronary intervention |
US7494488B2 (en) | 1998-05-28 | 2009-02-24 | Pearl Technology Holdings, Llc | Facial tissue strengthening and tightening device and methods |
US7198635B2 (en) | 2000-10-17 | 2007-04-03 | Asthmatx, Inc. | Modification of airways by application of energy |
EP1109591A4 (en) | 1998-06-12 | 2004-08-18 | Cardiac Pacemakers Inc | MODIFIED WIRE GUIDE FOR LEFT VENTRICLE ACCESS DIVERSION |
US6121775A (en) | 1998-06-16 | 2000-09-19 | Beth Israel Deaconess Medical Center, Inc. | MRI imaging method and apparatus |
WO1999065561A1 (en) | 1998-06-19 | 1999-12-23 | Cordis Webster, Inc. | Method and apparatus for transvascular treatment of tachycardia and fibrillation |
US6322559B1 (en) | 1998-07-06 | 2001-11-27 | Vnus Medical Technologies, Inc. | Electrode catheter having coil structure |
US6394096B1 (en) | 1998-07-15 | 2002-05-28 | Corazon Technologies, Inc. | Method and apparatus for treatment of cardiovascular tissue mineralization |
US9415222B2 (en) | 1998-08-05 | 2016-08-16 | Cyberonics, Inc. | Monitoring an epilepsy disease state with a supervisory module |
US6152943A (en) | 1998-08-14 | 2000-11-28 | Incept Llc | Methods and apparatus for intraluminal deposition of hydrogels |
US6228109B1 (en) | 1998-08-31 | 2001-05-08 | Lily Chen Tu | Methods for treating atherosclerosis and vulnerable plaques |
US5980563A (en) | 1998-08-31 | 1999-11-09 | Tu; Lily Chen | Ablation apparatus and methods for treating atherosclerosis |
US20050080374A1 (en) | 1998-09-01 | 2005-04-14 | Brady Esch | Method and apparatus for treating acute myocardial infarction with selective hypothermic perfusion |
US6251128B1 (en) | 1998-09-01 | 2001-06-26 | Fidus Medical Technology Corporation | Microwave ablation catheter with loop configuration |
US6123702A (en) | 1998-09-10 | 2000-09-26 | Scimed Life Systems, Inc. | Systems and methods for controlling power in an electrosurgical probe |
US6183468B1 (en) | 1998-09-10 | 2001-02-06 | Scimed Life Systems, Inc. | Systems and methods for controlling power in an electrosurgical probe |
US6489307B1 (en) | 1998-09-14 | 2002-12-03 | University Of Florida | Antisense compositions targeted to β1-adrenoceptor-specific mRNA and methods of use |
US6425867B1 (en) | 1998-09-18 | 2002-07-30 | University Of Washington | Noise-free real time ultrasonic imaging of a treatment site undergoing high intensity focused ultrasound therapy |
US7722539B2 (en) | 1998-09-18 | 2010-05-25 | University Of Washington | Treatment of unwanted tissue by the selective destruction of vasculature providing nutrients to the tissue |
US6299379B1 (en) | 1998-09-18 | 2001-10-09 | Lewis Hunting Accessories, Mfg., Inc. | Reflective trail markers |
US6123703A (en) | 1998-09-19 | 2000-09-26 | Tu; Lily Chen | Ablation catheter and methods for treating tissues |
US6036689A (en) | 1998-09-24 | 2000-03-14 | Tu; Lily Chen | Ablation device for treating atherosclerotic tissues |
US6319251B1 (en) | 1998-09-24 | 2001-11-20 | Hosheng Tu | Medical device and methods for treating intravascular restenosis |
US20060240070A1 (en) | 1998-09-24 | 2006-10-26 | Cromack Keith R | Delivery of highly lipophilic agents via medical devices |
US8257724B2 (en) | 1998-09-24 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
AU5882599A (en) | 1998-09-24 | 2000-04-10 | Super Dimension Ltd. | System and method for determining the location of a catheter during an intra-body medical procedure |
US6283935B1 (en) | 1998-09-30 | 2001-09-04 | Hearten Medical | Ultrasonic device for providing reversible tissue damage to heart muscle |
US7137980B2 (en) | 1998-10-23 | 2006-11-21 | Sherwood Services Ag | Method and system for controlling output of RF medical generator |
US6796981B2 (en) | 1999-09-30 | 2004-09-28 | Sherwood Services Ag | Vessel sealing system |
US7901400B2 (en) | 1998-10-23 | 2011-03-08 | Covidien Ag | Method and system for controlling output of RF medical generator |
US6123718A (en) | 1998-11-02 | 2000-09-26 | Polymerex Medical Corp. | Balloon catheter |
US6701176B1 (en) | 1998-11-04 | 2004-03-02 | Johns Hopkins University School Of Medicine | Magnetic-resonance-guided imaging, electrophysiology, and ablation |
US6673290B1 (en) | 1998-11-12 | 2004-01-06 | Scimed Life Systems, Inc. | Electrode structure for heating and ablating tissue and method for making and assembling the same |
US6210406B1 (en) | 1998-12-03 | 2001-04-03 | Cordis Webster, Inc. | Split tip electrode catheter and signal processing RF ablation system |
US6129725A (en) | 1998-12-04 | 2000-10-10 | Tu; Lily Chen | Methods for reduction of restenosis |
US6078839A (en) | 1998-12-09 | 2000-06-20 | Pacesetter, Inc. | Abrasion resistant implantable lead insulation protector |
US20070066972A1 (en) | 2001-11-29 | 2007-03-22 | Medwaves, Inc. | Ablation catheter apparatus with one or more electrodes |
US6620139B1 (en) | 1998-12-14 | 2003-09-16 | Tre Esse Progettazione Biomedica S.R.L. | Catheter system for performing intramyocardiac therapeutic treatment |
US7066900B2 (en) | 1998-12-23 | 2006-06-27 | Life Therapeutics | Removal of metabolic components from blood |
US6106477A (en) | 1998-12-28 | 2000-08-22 | Medtronic, Inc. | Chronically implantable blood vessel cuff with sensor |
US6296619B1 (en) | 1998-12-30 | 2001-10-02 | Pharmasonics, Inc. | Therapeutic ultrasonic catheter for delivering a uniform energy dose |
US6102908A (en) | 1999-01-04 | 2000-08-15 | Tu; Lily Chen | Rotatable apparatus having ablation capabilities |
WO2000040955A1 (en) | 1999-01-05 | 2000-07-13 | Kaiku Limited | Impedance measurements of bodily matter |
US6206831B1 (en) | 1999-01-06 | 2001-03-27 | Scimed Life Systems, Inc. | Ultrasound-guided ablation catheter and methods of use |
US6228076B1 (en) | 1999-01-09 | 2001-05-08 | Intraluminal Therapeutics, Inc. | System and method for controlling tissue ablation |
US7481803B2 (en) | 2000-11-28 | 2009-01-27 | Flowmedica, Inc. | Intra-aortic renal drug delivery catheter |
US7329236B2 (en) | 1999-01-11 | 2008-02-12 | Flowmedica, Inc. | Intra-aortic renal drug delivery catheter |
US6749598B1 (en) | 1999-01-11 | 2004-06-15 | Flowmedica, Inc. | Apparatus and methods for treating congestive heart disease |
US7122019B1 (en) | 2000-11-28 | 2006-10-17 | Flowmedica Inc. | Intra-aortic renal drug delivery catheter |
US7780628B1 (en) | 1999-01-11 | 2010-08-24 | Angiodynamics, Inc. | Apparatus and methods for treating congestive heart disease |
US6695830B2 (en) | 1999-01-15 | 2004-02-24 | Scimed Life Systems, Inc. | Method for delivering medication into an arterial wall for prevention of restenosis |
US6191862B1 (en) | 1999-01-20 | 2001-02-20 | Lightlab Imaging, Llc | Methods and apparatus for high speed longitudinal scanning in imaging systems |
US6592526B1 (en) | 1999-01-25 | 2003-07-15 | Jay Alan Lenker | Resolution ultrasound devices for imaging and treatment of body lumens |
US6423057B1 (en) | 1999-01-25 | 2002-07-23 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method and apparatus for monitoring and controlling tissue temperature and lesion formation in radio-frequency ablation procedures |
US6113615A (en) | 1999-02-03 | 2000-09-05 | Scimed Life Systems, Inc. | Atherectomy burr including a bias wire |
US6236883B1 (en) | 1999-02-03 | 2001-05-22 | The Trustees Of Columbia University In The City Of New York | Methods and systems for localizing reentrant circuits from electrogram features |
US6203537B1 (en) | 1999-02-04 | 2001-03-20 | Sorin Adrian | Laser-driven acoustic ablation catheter |
WO2000047118A1 (en) | 1999-02-10 | 2000-08-17 | Swaminathan Jayaraman | Balloon catheter for cryotherapy and method of using same |
US6855123B2 (en) | 2002-08-02 | 2005-02-15 | Flow Cardia, Inc. | Therapeutic ultrasound system |
WO2000048525A2 (en) | 1999-02-19 | 2000-08-24 | Scimed Life Systems, Inc. | Laser lithotripsy device with suction |
US6468297B1 (en) | 1999-02-24 | 2002-10-22 | Cryovascular Systems, Inc. | Cryogenically enhanced intravascular interventions |
US6428534B1 (en) | 1999-02-24 | 2002-08-06 | Cryovascular Systems, Inc. | Cryogenic angioplasty catheter |
US6432102B2 (en) | 1999-03-15 | 2002-08-13 | Cryovascular Systems, Inc. | Cryosurgical fluid supply |
US6514245B1 (en) | 1999-03-15 | 2003-02-04 | Cryovascular Systems, Inc. | Safety cryotherapy catheter |
US6648879B2 (en) | 1999-02-24 | 2003-11-18 | Cryovascular Systems, Inc. | Safety cryotherapy catheter |
CA2364098C (en) | 1999-03-09 | 2010-11-16 | Thermage, Inc. | Apparatus and method for treatment of tissue |
US6911026B1 (en) | 1999-07-12 | 2005-06-28 | Stereotaxis, Inc. | Magnetically guided atherectomy |
US6484052B1 (en) | 1999-03-30 | 2002-11-19 | The Regents Of The University Of California | Optically generated ultrasound for enhanced drug delivery |
US6409723B1 (en) | 1999-04-02 | 2002-06-25 | Stuart D. Edwards | Treating body tissue by applying energy and substances |
US6325797B1 (en) | 1999-04-05 | 2001-12-04 | Medtronic, Inc. | Ablation catheter and method for isolating a pulmonary vein |
US6702811B2 (en) | 1999-04-05 | 2004-03-09 | Medtronic, Inc. | Ablation catheter assembly with radially decreasing helix and method of use |
US20010007070A1 (en) | 1999-04-05 | 2001-07-05 | Medtronic, Inc. | Ablation catheter assembly and method for isolating a pulmonary vein |
US20050010095A1 (en) | 1999-04-05 | 2005-01-13 | Medtronic, Inc. | Multi-purpose catheter apparatus and method of use |
EP1171032A4 (en) | 1999-04-15 | 2008-10-29 | Surgi Vision | PROCESS FOR IN VIVO IMAGING BY MAGNETIC RESONANCE |
US6577902B1 (en) | 1999-04-16 | 2003-06-10 | Tony R. Brown | Device for shaping infarcted heart tissue and method of using the device |
US6317615B1 (en) | 1999-04-19 | 2001-11-13 | Cardiac Pacemakers, Inc. | Method and system for reducing arterial restenosis in the presence of an intravascular stent |
US6149647A (en) | 1999-04-19 | 2000-11-21 | Tu; Lily Chen | Apparatus and methods for tissue treatment |
US6595959B1 (en) | 1999-04-23 | 2003-07-22 | Alexander A. Stratienko | Cardiovascular sheath/catheter |
US6245045B1 (en) | 1999-04-23 | 2001-06-12 | Alexander Andrew Stratienko | Combination sheath and catheter for cardiovascular use |
US6514236B1 (en) | 1999-04-23 | 2003-02-04 | Alexander A. Stratienko | Method for treating a cardiovascular condition |
US6689142B1 (en) | 1999-04-26 | 2004-02-10 | Scimed Life Systems, Inc. | Apparatus and methods for guiding a needle |
AU4600600A (en) | 1999-04-26 | 2000-11-10 | Simage Oy | Self triggered imaging device for imaging radiation |
US7226446B1 (en) | 1999-05-04 | 2007-06-05 | Dinesh Mody | Surgical microwave ablation assembly |
US6648854B1 (en) | 1999-05-14 | 2003-11-18 | Scimed Life Systems, Inc. | Single lumen balloon-tipped micro catheter with reinforced shaft |
US6692490B1 (en) | 1999-05-18 | 2004-02-17 | Novasys Medical, Inc. | Treatment of urinary incontinence and other disorders by application of energy and drugs |
EP1180004A1 (en) | 1999-05-18 | 2002-02-20 | Silhouette Medical Inc. | Surgical weight control device |
US7343195B2 (en) | 1999-05-18 | 2008-03-11 | Mediguide Ltd. | Method and apparatus for real time quantitative three-dimensional image reconstruction of a moving organ and intra-body navigation |
GB9911956D0 (en) | 1999-05-21 | 1999-07-21 | Gyrus Medical Ltd | Electrosurgery system and method |
US6375668B1 (en) | 1999-06-02 | 2002-04-23 | Hanson S. Gifford | Devices and methods for treating vascular malformations |
US6391024B1 (en) | 1999-06-17 | 2002-05-21 | Cardiac Pacemakers, Inc. | RF ablation apparatus and method having electrode/tissue contact assessment scheme and electrocardiogram filtering |
US6398792B1 (en) | 1999-06-21 | 2002-06-04 | O'connor Lawrence | Angioplasty catheter with transducer using balloon for focusing of ultrasonic energy and method for use |
SE519023C2 (sv) | 1999-06-21 | 2002-12-23 | Micromuscle Ab | Kateterburna mikrokirurgiska verktygsset |
US6546272B1 (en) | 1999-06-24 | 2003-04-08 | Mackinnon Nicholas B. | Apparatus for in vivo imaging of the respiratory tract and other internal organs |
EP1198271A4 (en) | 1999-06-25 | 2009-01-21 | Univ Emory | DEVICES AND METHODS FOR STIMULATING THE VAGUSNERVS |
US7426409B2 (en) | 1999-06-25 | 2008-09-16 | Board Of Regents, The University Of Texas System | Method and apparatus for detecting vulnerable atherosclerotic plaque |
US6238392B1 (en) | 1999-06-29 | 2001-05-29 | Ethicon Endo-Surgery, Inc. | Bipolar electrosurgical instrument including a plurality of balloon electrodes |
US6179859B1 (en) | 1999-07-16 | 2001-01-30 | Baff Llc | Emboli filtration system and methods of use |
US6508804B2 (en) | 1999-07-28 | 2003-01-21 | Scimed Life Systems, Inc. | Catheter having continuous lattice and coil reinforcement |
US6203561B1 (en) | 1999-07-30 | 2001-03-20 | Incept Llc | Integrated vascular device having thrombectomy element and vascular filter and methods of use |
US6235044B1 (en) | 1999-08-04 | 2001-05-22 | Scimed Life Systems, Inc. | Percutaneous catheter and guidewire for filtering during ablation of mycardial or vascular tissue |
US7033372B1 (en) | 1999-08-04 | 2006-04-25 | Percardia, Inc. | Corkscrew reinforced left ventricle to coronary artery channel |
DE60008072T2 (de) | 1999-08-05 | 2004-08-05 | Broncus Technologies, Inc., Mountain View | Verfahren und vorrichtungen zur herstellung von kollateralen kanälen in den lungen |
US7175644B2 (en) | 2001-02-14 | 2007-02-13 | Broncus Technologies, Inc. | Devices and methods for maintaining collateral channels in tissue |
DE29913688U1 (de) | 1999-08-05 | 1999-10-14 | Wolf Gmbh Richard | Transurethrale Dissektionselektrode |
US6445939B1 (en) | 1999-08-09 | 2002-09-03 | Lightlab Imaging, Llc | Ultra-small optical probes, imaging optics, and methods for using same |
FR2797389B1 (fr) | 1999-08-09 | 2001-11-30 | Novatech Inc | Prothese aortique bifurquee |
US7288096B2 (en) | 2003-01-17 | 2007-10-30 | Origin Medsystems, Inc. | Apparatus for placement of cardiac defibrillator and pacer |
US6575966B2 (en) | 1999-08-23 | 2003-06-10 | Cryocath Technologies Inc. | Endovascular cryotreatment catheter |
US6283959B1 (en) | 1999-08-23 | 2001-09-04 | Cyrocath Technologies, Inc. | Endovascular cryotreatment catheter |
US6298256B1 (en) | 1999-09-10 | 2001-10-02 | Frank-Egbert Meyer | Device and method for the location and catheterization of the surroundings of a nerve |
US6454775B1 (en) | 1999-12-06 | 2002-09-24 | Bacchus Vascular Inc. | Systems and methods for clot disruption and retrieval |
NL1013084C2 (nl) | 1999-09-17 | 2001-03-20 | Neopost Bv | Instellen van een systeem voor het samenstellen van poststukken. |
US6829497B2 (en) | 1999-09-21 | 2004-12-07 | Jamil Mogul | Steerable diagnostic catheters |
JP2003510126A (ja) | 1999-09-28 | 2003-03-18 | ノヴァシス メディカル インコーポレイテッド | エネルギーと薬の適用による組織の処置 |
US6485489B2 (en) | 1999-10-02 | 2002-11-26 | Quantum Cor, Inc. | Catheter system for repairing a mitral valve annulus |
JP2001116565A (ja) | 1999-10-15 | 2001-04-27 | Yazaki Corp | 車載ナビゲーション装置及び車載ナビゲーション装置における処理プログラムを記録した記録媒体 |
US6514248B1 (en) | 1999-10-15 | 2003-02-04 | Neothermia Corporation | Accurate cutting about and into tissue volumes with electrosurgically deployed electrodes |
US6669655B1 (en) | 1999-10-20 | 2003-12-30 | Transurgical, Inc. | Sonic element and catheter incorporating same |
CA2387127A1 (en) | 1999-10-25 | 2001-05-17 | Therus Corporation | Use of focused ultrasound for vascular sealing |
EP1229829B1 (en) | 1999-11-10 | 2008-01-09 | Cytyc Surgical Products | System for detecting perforations in a body cavity |
US6529756B1 (en) | 1999-11-22 | 2003-03-04 | Scimed Life Systems, Inc. | Apparatus for mapping and coagulating soft tissue in or around body orifices |
US6542781B1 (en) | 1999-11-22 | 2003-04-01 | Scimed Life Systems, Inc. | Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
EP1237472A4 (en) | 1999-11-24 | 2008-04-30 | Nuvasive Inc | SLEKTROMYOGRAPHIESYSTEM |
US6280466B1 (en) | 1999-12-03 | 2001-08-28 | Teramed Inc. | Endovascular graft system |
US6592567B1 (en) | 1999-12-07 | 2003-07-15 | Chf Solutions, Inc. | Kidney perfusion catheter |
US7097641B1 (en) | 1999-12-09 | 2006-08-29 | Cryocath Technologies Inc. | Catheter with cryogenic and heating ablation |
US6800075B2 (en) | 1999-12-10 | 2004-10-05 | Sprite Solutions | Method to inject and extract fluid at a treatment site to remove debris |
US7494485B2 (en) | 1999-12-10 | 2009-02-24 | Sprite Solutions | Fluidic interventional device and method of distal protection |
US6480745B2 (en) | 1999-12-24 | 2002-11-12 | Medtronic, Inc. | Information network interrogation of an implanted device |
US6494891B1 (en) | 1999-12-30 | 2002-12-17 | Advanced Cardiovascular Systems, Inc. | Ultrasonic angioplasty transmission member |
US6440125B1 (en) | 2000-01-04 | 2002-08-27 | Peter Rentrop | Excimer laser catheter |
US6328699B1 (en) | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
US6623453B1 (en) | 2000-01-19 | 2003-09-23 | Vanny Corporation | Chemo-thermo applicator for cancer treatment |
US6692450B1 (en) | 2000-01-19 | 2004-02-17 | Medtronic Xomed, Inc. | Focused ultrasound ablation devices having selectively actuatable ultrasound emitting elements and methods of using the same |
US7706882B2 (en) | 2000-01-19 | 2010-04-27 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area |
US6447443B1 (en) | 2001-01-13 | 2002-09-10 | Medtronic, Inc. | Method for organ positioning and stabilization |
US7184827B1 (en) | 2000-01-24 | 2007-02-27 | Stuart D. Edwards | Shrinkage of dilatations in the body |
US6569109B2 (en) | 2000-02-04 | 2003-05-27 | Olympus Optical Co., Ltd. | Ultrasonic operation apparatus for performing follow-up control of resonance frequency drive of ultrasonic oscillator by digital PLL system using DDS (direct digital synthesizer) |
US6457365B1 (en) | 2000-02-09 | 2002-10-01 | Endosonics Corporation | Method and apparatus for ultrasonic imaging |
US6663622B1 (en) | 2000-02-11 | 2003-12-16 | Iotek, Inc. | Surgical devices and methods for use in tissue ablation procedures |
US6158250A (en) | 2000-02-14 | 2000-12-12 | Novacept | Flat-bed knitting machine and method of knitting |
US7499745B2 (en) | 2000-02-28 | 2009-03-03 | Barbara Ann Karmanos Cancer Institute | Multidimensional bioelectrical tissue analyzer |
US6394956B1 (en) | 2000-02-29 | 2002-05-28 | Scimed Life Systems, Inc. | RF ablation and ultrasound catheter for crossing chronic total occlusions |
US6770070B1 (en) | 2000-03-17 | 2004-08-03 | Rita Medical Systems, Inc. | Lung treatment apparatus and method |
US6458098B1 (en) | 2000-03-17 | 2002-10-01 | Nozomu Kanesaka | Vascular therapy device |
DE60135836D1 (en) | 2000-03-24 | 2008-10-30 | Prorhythm Inc | Gerät zur intrakorporalen thermotherapie |
US6471696B1 (en) | 2000-04-12 | 2002-10-29 | Afx, Inc. | Microwave ablation instrument with a directional radiation pattern |
US20020107514A1 (en) | 2000-04-27 | 2002-08-08 | Hooven Michael D. | Transmural ablation device with parallel jaws |
US6558382B2 (en) | 2000-04-27 | 2003-05-06 | Medtronic, Inc. | Suction stabilized epicardial ablation devices |
AU2001253654A1 (en) | 2000-04-27 | 2001-11-12 | Medtronic, Inc. | Vibration sensitive ablation apparatus and method |
DE60138319D1 (de) | 2000-05-03 | 2009-05-20 | Bard Inc C R | Gerät zur Darstellung und Ablation bei elektrophysiologischen Verfahren |
WO2001087172A1 (en) | 2000-05-12 | 2001-11-22 | Cardima, Inc. | Multi-channel rf energy delivery with coagulum reduction |
US7252664B2 (en) | 2000-05-12 | 2007-08-07 | Cardima, Inc. | System and method for multi-channel RF energy delivery with coagulum reduction |
US7181261B2 (en) | 2000-05-15 | 2007-02-20 | Silver James H | Implantable, retrievable, thrombus minimizing sensors |
US6442413B1 (en) | 2000-05-15 | 2002-08-27 | James H. Silver | Implantable sensor |
US7006858B2 (en) | 2000-05-15 | 2006-02-28 | Silver James H | Implantable, retrievable sensors and immunosensors |
WO2001087154A1 (en) | 2000-05-18 | 2001-11-22 | Nuvasive, Inc. | Tissue discrimination and applications in medical procedures |
US6544780B1 (en) | 2000-06-02 | 2003-04-08 | Genphar, Inc. | Adenovirus vector with multiple expression cassettes |
US6511500B1 (en) | 2000-06-06 | 2003-01-28 | Marc Mounir Rahme | Use of autonomic nervous system neurotransmitters inhibition and atrial parasympathetic fibers ablation for the treatment of atrial arrhythmias and to preserve drug effects |
US20020022864A1 (en) | 2000-06-07 | 2002-02-21 | Mahvi David M. | Multipolar electrode system for radiofrequency ablation |
US6752805B2 (en) | 2000-06-13 | 2004-06-22 | Atrionix, Inc. | Surgical ablation probe for forming a circumferential lesion |
US7837720B2 (en) | 2000-06-20 | 2010-11-23 | Boston Scientific Corporation | Apparatus for treatment of tissue adjacent a bodily conduit with a gene or drug-coated compression balloon |
US6958075B2 (en) | 2001-09-18 | 2005-10-25 | Celsion Corporation | Device and method for treatment of tissue adjacent a bodily conduit by thermocompression |
US6477426B1 (en) | 2000-06-20 | 2002-11-05 | Celsion Corporation | System and method for heating the prostate gland to treat and prevent the growth and spread of prostate tumors |
EP1365800B1 (en) | 2000-06-28 | 2013-03-06 | Ira Sanders | Methods for using tetanus toxin for benificial purposes in animals (mammals) |
US6511478B1 (en) | 2000-06-30 | 2003-01-28 | Scimed Life Systems, Inc. | Medical probe with reduced number of temperature sensor wires |
US6638277B2 (en) | 2000-07-06 | 2003-10-28 | Scimed Life Systems, Inc. | Tumor ablation needle with independently activated and independently traversing tines |
US20020095197A1 (en) | 2000-07-11 | 2002-07-18 | Lardo Albert C. | Application of photochemotherapy for the treatment of cardiac arrhythmias |
CA2415134C (en) | 2000-07-13 | 2015-09-22 | Transurgical, Inc. | Thermal treatment methods and apparatus with focused energy application |
DE10038737A1 (de) | 2000-08-02 | 2002-02-14 | Oliver Wendt | Katheter für magnetresonanztomographische Untersuchungen |
US7678106B2 (en) | 2000-08-09 | 2010-03-16 | Halt Medical, Inc. | Gynecological ablation procedure and system |
US6699241B2 (en) | 2000-08-11 | 2004-03-02 | Northeastern University | Wide-aperture catheter-based microwave cardiac ablation antenna |
US7789876B2 (en) | 2000-08-14 | 2010-09-07 | Tyco Healthcare Group, Lp | Method and apparatus for positioning a catheter relative to an anatomical junction |
US20040010118A1 (en) | 2000-08-16 | 2004-01-15 | Zerhusen Bryan D. | Novel proteins and nucleic acids encoding same |
US6497711B1 (en) | 2000-08-16 | 2002-12-24 | Scimed Life Systems, Inc. | Therectomy device having a light weight drive shaft and an imaging device |
US6955174B2 (en) | 2000-08-18 | 2005-10-18 | Uryovascular Systems, Inc. | Cryotherapy method for detecting and treating vulnerable plaque |
US6602246B1 (en) | 2000-08-18 | 2003-08-05 | Cryovascular Systems, Inc. | Cryotherapy method for detecting and treating vulnerable plaque |
US6669692B1 (en) | 2000-08-21 | 2003-12-30 | Biosense Webster, Inc. | Ablation catheter with cooled linear electrode |
DE60142693D1 (de) | 2000-09-08 | 2010-09-09 | Daiichi Sankyo Co Ltd | Arzneimittel für herzversagen |
US6511496B1 (en) | 2000-09-12 | 2003-01-28 | Advanced Cardiovascular Systems, Inc. | Embolic protection device for use in interventional procedures |
US6522926B1 (en) | 2000-09-27 | 2003-02-18 | Cvrx, Inc. | Devices and methods for cardiovascular reflex control |
US6985774B2 (en) | 2000-09-27 | 2006-01-10 | Cvrx, Inc. | Stimulus regimens for cardiovascular reflex control |
US7158832B2 (en) | 2000-09-27 | 2007-01-02 | Cvrx, Inc. | Electrode designs and methods of use for cardiovascular reflex control devices |
US6845267B2 (en) | 2000-09-28 | 2005-01-18 | Advanced Bionics Corporation | Systems and methods for modulation of circulatory perfusion by electrical and/or drug stimulation |
US6470219B1 (en) | 2000-10-02 | 2002-10-22 | Novasys Medical, Inc. | Apparatus and method for treating female urinary incontinence |
US6527765B2 (en) | 2000-10-06 | 2003-03-04 | Charles D. Kelman | Cryogenic surgical system and method of use in removal of tissue |
US6802857B1 (en) | 2000-10-11 | 2004-10-12 | Uab Research Foundation | MRI stent |
US6475215B1 (en) | 2000-10-12 | 2002-11-05 | Naim Erturk Tanrisever | Quantum energy surgical device and method |
US7104987B2 (en) | 2000-10-17 | 2006-09-12 | Asthmatx, Inc. | Control system and process for application of energy to airway walls and other mediums |
US7646544B2 (en) | 2005-05-14 | 2010-01-12 | Batchko Robert G | Fluidic optical devices |
US6706037B2 (en) | 2000-10-24 | 2004-03-16 | Galil Medical Ltd. | Multiple cryoprobe apparatus and method |
US6616624B1 (en) | 2000-10-30 | 2003-09-09 | Cvrx, Inc. | Systems and method for controlling renovascular perfusion |
US20060062786A1 (en) | 2000-11-08 | 2006-03-23 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20070292411A1 (en) | 2000-11-08 | 2007-12-20 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
US6673066B2 (en) | 2000-11-10 | 2004-01-06 | Cardiostream, Inc. | Apparatus and method to diagnose and treat vulnerable plaque |
US6942692B2 (en) | 2000-11-16 | 2005-09-13 | Cordis Corporation | Supra-renal prosthesis and renal artery bypass |
JP5377813B2 (ja) | 2000-11-16 | 2013-12-25 | コヴィディエン リミテッド パートナーシップ | ヒト食道内の異常組織を処置するシステム及び方法 |
US7314483B2 (en) | 2000-11-16 | 2008-01-01 | Cordis Corp. | Stent graft with branch leg |
CA2429725C (en) | 2000-11-24 | 2010-02-09 | Innovacell Biotechnologie Gmbh | Ultrasonic probe comprising a positioning device for examination devices and operation devices |
US6579308B1 (en) | 2000-11-28 | 2003-06-17 | Scimed Life Systems, Inc. | Stent devices with detachable distal or proximal wires |
US7081114B2 (en) | 2000-11-29 | 2006-07-25 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Electrophysiology/ablation catheter having lariat configuration of variable radius |
US6676657B2 (en) | 2000-12-07 | 2004-01-13 | The United States Of America As Represented By The Department Of Health And Human Services | Endoluminal radiofrequency cauterization system |
US6659981B2 (en) | 2000-12-08 | 2003-12-09 | Medtronic, Inc. | Medical device delivery catheter with distal locator |
US6623452B2 (en) | 2000-12-19 | 2003-09-23 | Scimed Life Systems, Inc. | Drug delivery catheter having a highly compliant balloon with infusion holes |
US6620157B1 (en) * | 2000-12-28 | 2003-09-16 | Senorx, Inc. | High frequency power source |
US20020087151A1 (en) | 2000-12-29 | 2002-07-04 | Afx, Inc. | Tissue ablation apparatus with a sliding ablation instrument and method |
DE60238178D1 (de) | 2001-01-16 | 2010-12-16 | Cytyc Surgical Products Palo A | Vorrichtung und verfahren zur behandlung des venösen reflux |
US6569177B1 (en) | 2001-01-19 | 2003-05-27 | Scimed Life Systems, Inc. | Ablation atherectomy burr |
CA2435304C (en) | 2001-01-19 | 2010-01-05 | Boston Scientific Limited | Introducer for deployment of branched prosthesis |
US20020107536A1 (en) | 2001-02-07 | 2002-08-08 | Hussein Hany M. | Device and method for preventing kidney failure |
US6823205B1 (en) | 2001-02-08 | 2004-11-23 | Boston University Radiology Associates | Synthetic images for a magnetic resonance imaging scanner using linear combination of source images to generate contrast and spatial navigation |
CN1496271B (zh) | 2001-02-16 | 2010-04-28 | 阿斯比奥制药株式会社 | 伴随有aop-1基因或aop-1的表达减少的疾病的治疗方法以及该疾病的治疗药 |
AUPR333301A0 (en) | 2001-02-23 | 2001-03-22 | Northern Sydney Area Health Service | Determining the volume of a normal heart and its pathological and treated variants by using dimension sensors |
US6564096B2 (en) | 2001-02-28 | 2003-05-13 | Robert A. Mest | Method and system for treatment of tachycardia and fibrillation |
US6994093B2 (en) | 2001-02-28 | 2006-02-07 | Chase Medical, L.P. | Ventricular restoration shaping apparatus and method of use |
US6666863B2 (en) | 2001-03-01 | 2003-12-23 | Scimed Life Systems, Inc. | Device and method for percutaneous myocardial revascularization |
US6786904B2 (en) | 2002-01-10 | 2004-09-07 | Triton Biosystems, Inc. | Method and device to treat vulnerable plaque |
WO2002085920A2 (en) | 2001-03-08 | 2002-10-31 | Oralbekov, Bakytzhan | Alkane and alkane group dehydrogenation with organometallic catalysts |
US6570659B2 (en) | 2001-03-16 | 2003-05-27 | Lightlab Imaging, Llc | Broadband light source system and method and light source combiner |
US6623444B2 (en) | 2001-03-21 | 2003-09-23 | Advanced Medical Applications, Inc. | Ultrasonic catheter drug delivery method and device |
US20020147480A1 (en) | 2001-04-04 | 2002-10-10 | Mamayek Donald S. | Treatment of lipid pool |
US6552796B2 (en) | 2001-04-06 | 2003-04-22 | Lightlab Imaging, Llc | Apparatus and method for selective data collection and signal to noise ratio enhancement using optical coherence tomography |
US6764501B2 (en) | 2001-04-10 | 2004-07-20 | Robert A. Ganz | Apparatus and method for treating atherosclerotic vascular disease through light sterilization |
US6666858B2 (en) | 2001-04-12 | 2003-12-23 | Scimed Life Systems, Inc. | Cryo balloon for atrial ablation |
US7402312B2 (en) | 2001-04-13 | 2008-07-22 | Human Genome Sciences, Inc. | Antibodies to vascular endothelial growth factor 2 (VEGF-2) |
US20050232921A1 (en) | 2001-04-13 | 2005-10-20 | Rosen Craig A | Vascular endothelial growth factor 2 |
US6989010B2 (en) | 2001-04-26 | 2006-01-24 | Medtronic, Inc. | Ablation system and method of use |
US6645223B2 (en) | 2001-04-30 | 2003-11-11 | Advanced Cardiovascular Systems, Inc. | Deployment and recovery control systems for embolic protection devices |
WO2002087456A1 (en) | 2001-05-01 | 2002-11-07 | C.R. Bard, Inc. | Method and apparatus for altering conduction properties in the heart and in adjacent vessels |
US20020169444A1 (en) | 2001-05-08 | 2002-11-14 | Mest Robert A. | Catheter having continuous braided electrode |
WO2002089686A1 (en) | 2001-05-10 | 2002-11-14 | Rita Medical Systems, Inc. | Rf tissue ablation apparatus and method |
US20030130713A1 (en) | 2001-05-21 | 2003-07-10 | Stewart Mark T. | Trans-septal catheter with retention mechanism |
US6771996B2 (en) | 2001-05-24 | 2004-08-03 | Cardiac Pacemakers, Inc. | Ablation and high-resolution mapping catheter system for pulmonary vein foci elimination |
US7348003B2 (en) | 2001-05-25 | 2008-03-25 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors |
US7361341B2 (en) | 2001-05-25 | 2008-04-22 | Human Genome Sciences, Inc. | Methods of treating cancer using antibodies that immunospecifically bind to trail receptors |
US20050214209A1 (en) | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20090226429A1 (en) | 2001-05-25 | 2009-09-10 | Human Genome Sciences, Inc. | Antibodies That Immunospecifically Bind to TRAIL Receptors |
US20050129616A1 (en) | 2001-05-25 | 2005-06-16 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20050214210A1 (en) | 2001-05-25 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
JP2004532251A (ja) | 2001-05-31 | 2004-10-21 | ミラヴァント ファーマシューティカルズ インコーポレイテッド | 光線力学療法で使用のメタロテトラピロール系光増感剤 |
US20020198520A1 (en) | 2001-06-20 | 2002-12-26 | Scimed Life Systems, Inc. | Irrigation sheath |
US6797933B1 (en) | 2001-06-29 | 2004-09-28 | Vanguard International Semiconductor Corporation | On-chip design-for-testing structure for CMOS APS (active pixel sensor) image sensor |
US6605056B2 (en) | 2001-07-11 | 2003-08-12 | Scimed Life Systems, Inc. | Conformable balloon |
US20060167498A1 (en) | 2001-07-23 | 2006-07-27 | Dilorenzo Daniel J | Method, apparatus, and surgical technique for autonomic neuromodulation for the treatment of disease |
US20040043030A1 (en) | 2001-07-31 | 2004-03-04 | Immunomedics, Inc. | Polymeric delivery systems |
CA2456047A1 (en) | 2001-08-08 | 2003-02-20 | Canica Design Inc. | Surgical retractor and tissue stabilization device |
US6786900B2 (en) | 2001-08-13 | 2004-09-07 | Cryovascular Systems, Inc. | Cryotherapy methods for treating vessel dissections and side branch occlusion |
US6600956B2 (en) | 2001-08-21 | 2003-07-29 | Cyberonics, Inc. | Circumneural electrode assembly |
US20030050635A1 (en) | 2001-08-22 | 2003-03-13 | Csaba Truckai | Embolization systems and techniques for treating tumors |
AU2002324775A1 (en) | 2001-08-23 | 2003-03-10 | Sciperio, Inc. | Architecture tool and methods of use |
US8287524B2 (en) | 2001-08-23 | 2012-10-16 | Jerry Siegel | Apparatus and method for performing radiation energy treatments |
JP4280865B2 (ja) | 2001-08-31 | 2009-06-17 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 経皮プリングル閉塞デバイス |
US6962584B1 (en) | 2001-09-06 | 2005-11-08 | Stone Gregg W | Electromagnetic photonic catheter for reducing restenosis |
US7252679B2 (en) | 2001-09-13 | 2007-08-07 | Cordis Corporation | Stent with angulated struts |
AU2002326952A1 (en) | 2001-09-19 | 2003-04-01 | Urologix, Inc. | Microwave ablation device |
JP2005527474A (ja) | 2001-09-20 | 2005-09-15 | コーネル リサーチ ファンデーション インコーポレーテッド | 前立腺特異的膜抗原に特異的な結合剤を用いて、皮膚障害を治療するかまたは防止するための方法および組成物 |
US6723043B2 (en) | 2001-09-25 | 2004-04-20 | Sdgi Holdings, Inc. | Methods and devices for inserting and manipulating surgical instruments |
ATE320767T1 (de) | 2001-09-28 | 2006-04-15 | Rita Medical Systems Inc | Impedanzgesteuerte vorrichtung zur ablation von gewebe |
JP3607231B2 (ja) | 2001-09-28 | 2005-01-05 | 有限会社日本エレクテル | 高周波加温バルーンカテーテル |
JP2003111848A (ja) | 2001-10-05 | 2003-04-15 | Nihon Medix | 加熱式バルーンカテーテル装置およびその加熱方法 |
BR0213130B1 (pt) | 2001-10-06 | 2014-10-07 | Medos S A | Método para regular uma microválvula ajustável, microválvula ajustável, arranjo de microválvula implantável e bomba implantável |
US6814730B2 (en) | 2001-10-09 | 2004-11-09 | Hong Li | Balloon catheters for non-continuous lesions |
US6926716B2 (en) | 2001-11-09 | 2005-08-09 | Surgrx Inc. | Electrosurgical instrument |
AUPR847201A0 (en) | 2001-10-26 | 2001-11-15 | Cook Incorporated | Endoluminal graft |
US6807444B2 (en) | 2001-11-05 | 2004-10-19 | Hosheng Tu | Apparatus and methods for monitoring tissue impedance |
US20030092995A1 (en) | 2001-11-13 | 2003-05-15 | Medtronic, Inc. | System and method of positioning implantable medical devices |
US7317077B2 (en) | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
WO2003043685A2 (en) | 2001-11-19 | 2003-05-30 | Cardiovascular Systems, Inc | High torque, low profile intravascular guidewire system |
US6895077B2 (en) | 2001-11-21 | 2005-05-17 | University Of Massachusetts Medical Center | System and method for x-ray fluoroscopic imaging |
DE60209799T2 (de) | 2001-12-03 | 2007-01-25 | Ekos Corp., Bothell | Katheter mit mehreren ultraschall-abstrahlenden teilen |
WO2007136946A2 (en) | 2001-12-03 | 2007-11-29 | Xtent, Inc. | Delivery catheter having active engagement mechanism for prosthesis |
US6849075B2 (en) | 2001-12-04 | 2005-02-01 | Estech, Inc. | Cardiac ablation devices and methods |
US20050149069A1 (en) | 2001-12-04 | 2005-07-07 | Bertolero Arthur A. | Left atrial appendage devices and methods |
US6709431B2 (en) | 2001-12-18 | 2004-03-23 | Scimed Life Systems, Inc. | Cryo-temperature monitoring |
US20050214205A1 (en) | 2001-12-20 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
CA2471140A1 (en) | 2001-12-20 | 2003-07-03 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to trail receptors |
US20050214208A1 (en) | 2001-12-20 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to TRAIL receptors |
US20050214207A1 (en) | 2001-12-20 | 2005-09-29 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind toTRAIL receptors |
US6972024B1 (en) | 2001-12-21 | 2005-12-06 | Advanced Cardiovascular Systems, Inc. | Method of treating vulnerable plaque |
US6893436B2 (en) | 2002-01-03 | 2005-05-17 | Afx, Inc. | Ablation instrument having a flexible distal portion |
US7326237B2 (en) | 2002-01-08 | 2008-02-05 | Cordis Corporation | Supra-renal anchoring prosthesis |
EP2327954A1 (en) | 2002-01-11 | 2011-06-01 | The General Hospital Corporation | Apparatus for OCT imaging with axial line focus for improved resolution and depth of field |
US6814733B2 (en) | 2002-01-31 | 2004-11-09 | Biosense, Inc. | Radio frequency pulmonary vein isolation |
US6790206B2 (en) | 2002-01-31 | 2004-09-14 | Scimed Life Systems, Inc. | Compensation for power variation along patient cables |
US6826830B2 (en) | 2002-02-05 | 2004-12-07 | International Business Machines Corporation | Multi-layered interconnect structure using liquid crystalline polymer dielectric |
US6949121B1 (en) | 2002-02-07 | 2005-09-27 | Sentient Engineering & Technology, Llc | Apparatus and methods for conduits and materials |
MXPA04007897A (es) | 2002-02-15 | 2004-11-26 | Celsion Corp | Metodo y aparato para tratar el tejido adyacente a un conducto corporal con termocompresion y farmacos. |
US7192427B2 (en) | 2002-02-19 | 2007-03-20 | Afx, Inc. | Apparatus and method for assessing transmurality of a tissue ablation |
IL163525A0 (en) | 2002-02-21 | 2005-12-18 | Wyeth Corp | A follistatin domain containing protein |
US7294127B2 (en) | 2002-03-05 | 2007-11-13 | Baylis Medical Company Inc. | Electrosurgical tissue treatment method |
US6824516B2 (en) | 2002-03-11 | 2004-11-30 | Medsci Technologies, Inc. | System for examining, mapping, diagnosing, and treating diseases of the prostate |
WO2003089997A2 (en) | 2002-03-15 | 2003-10-30 | C.R. Bard, Inc. | Method and apparatus for control of ablation energy and electrogram acquisition through multiple common electrodes in an electrophysiology catheter |
ITBS20020039U1 (it) | 2002-03-20 | 2003-09-22 | Fogazzi Di Venturelli Andrea & | Catetere con elettrodo flessibile raffreddato |
US7087026B2 (en) | 2002-03-21 | 2006-08-08 | Radiant Medical, Inc. | Devices and methods for measuring blood flow rate or cardiac output and for heating or cooling the body |
US6979420B2 (en) | 2002-03-28 | 2005-12-27 | Scimed Life Systems, Inc. | Method of molding balloon catheters employing microwave energy |
US7853333B2 (en) | 2002-04-08 | 2010-12-14 | Ardian, Inc. | Methods and apparatus for multi-vessel renal neuromodulation |
US6978174B2 (en) | 2002-04-08 | 2005-12-20 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US20060206150A1 (en) | 2002-04-08 | 2006-09-14 | Ardian, Inc. | Methods and apparatus for treating acute myocardial infarction |
US8347891B2 (en) | 2002-04-08 | 2013-01-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen |
US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
US8145317B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods for renal neuromodulation |
US8145316B2 (en) | 2002-04-08 | 2012-03-27 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
US7162303B2 (en) | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
US7756583B2 (en) | 2002-04-08 | 2010-07-13 | Ardian, Inc. | Methods and apparatus for intravascularly-induced neuromodulation |
US8131371B2 (en) | 2002-04-08 | 2012-03-06 | Ardian, Inc. | Methods and apparatus for monopolar renal neuromodulation |
US20110207758A1 (en) | 2003-04-08 | 2011-08-25 | Medtronic Vascular, Inc. | Methods for Therapeutic Renal Denervation |
US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
US7620451B2 (en) | 2005-12-29 | 2009-11-17 | Ardian, Inc. | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach |
US6685733B1 (en) | 2002-04-10 | 2004-02-03 | Radiant Medical, Inc. | Methods and systems for reducing substance-induced renal damage |
US20050256398A1 (en) | 2004-05-12 | 2005-11-17 | Hastings Roger N | Systems and methods for interventional medicine |
US6989009B2 (en) | 2002-04-19 | 2006-01-24 | Scimed Life Systems, Inc. | Cryo balloon |
US20030199747A1 (en) | 2002-04-19 | 2003-10-23 | Michlitsch Kenneth J. | Methods and apparatus for the identification and stabilization of vulnerable plaque |
DE10217559B4 (de) | 2002-04-19 | 2004-02-19 | Universitätsklinikum Freiburg | Vorrichtung zur minimalinvasiven, intravasalen Aortenklappenextraktion |
US6746401B2 (en) | 2002-05-06 | 2004-06-08 | Scimed Life Systems, Inc. | Tissue ablation visualization |
EP1508157B1 (en) | 2002-05-08 | 2011-11-23 | Phoseon Technology, Inc. | High efficiency solid-state light source and methods of use and manufacture |
AUPS226402A0 (en) | 2002-05-13 | 2002-06-13 | Advanced Metal Coatings Pty Limited | An ablation catheter |
US6746474B2 (en) | 2002-05-31 | 2004-06-08 | Vahid Saadat | Apparatus and methods for cooling a region within the body |
US7153315B2 (en) | 2002-06-11 | 2006-12-26 | Boston Scientific Scimed, Inc. | Catheter balloon with ultrasonic microscalpel blades |
US6748953B2 (en) | 2002-06-11 | 2004-06-15 | Scimed Life Systems, Inc. | Method for thermal treatment of type II endoleaks in arterial aneurysms |
AU2003258976B2 (en) | 2002-06-28 | 2008-05-29 | Cook Incorporated | Thoracic aortic aneurysm stent graft. |
GB2390545B (en) | 2002-07-09 | 2005-04-20 | Barts & London Nhs Trust | Hollow organ probe |
US7769427B2 (en) | 2002-07-16 | 2010-08-03 | Magnetics, Inc. | Apparatus and method for catheter guidance control and imaging |
US6866662B2 (en) | 2002-07-23 | 2005-03-15 | Biosense Webster, Inc. | Ablation catheter having stabilizing array |
EP1545680B1 (en) | 2002-07-25 | 2010-09-08 | Boston Scientific Limited | Medical device for navigation through anatomy |
US8920826B2 (en) | 2002-07-31 | 2014-12-30 | Boston Scientific Scimed, Inc. | Medical imaging reference devices |
US6702748B1 (en) | 2002-09-20 | 2004-03-09 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
TWI235073B (en) | 2002-08-20 | 2005-07-01 | Toray Industries | Catheter for treating cardiac arrhythmias |
US6991617B2 (en) | 2002-08-21 | 2006-01-31 | Hektner Thomas R | Vascular treatment method and device |
US7604608B2 (en) | 2003-01-14 | 2009-10-20 | Flowcardia, Inc. | Ultrasound catheter and methods for making and using same |
US6942677B2 (en) | 2003-02-26 | 2005-09-13 | Flowcardia, Inc. | Ultrasound catheter apparatus |
US7335180B2 (en) | 2003-11-24 | 2008-02-26 | Flowcardia, Inc. | Steerable ultrasound catheter |
US7220233B2 (en) | 2003-04-08 | 2007-05-22 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US7137963B2 (en) | 2002-08-26 | 2006-11-21 | Flowcardia, Inc. | Ultrasound catheter for disrupting blood vessel obstructions |
US6929639B2 (en) | 2002-08-30 | 2005-08-16 | Scimed Life Systems, Inc. | Cryo ablation coil |
EP1585572A4 (en) | 2002-09-20 | 2010-02-24 | Flowmedica Inc | METHOD AND APPARATUS FOR ADMINISTERING INTRA-AORTIC SUBSTANCE TO A BRANCHED VESSEL |
US6942620B2 (en) | 2002-09-20 | 2005-09-13 | Flowcardia Inc | Connector for securing ultrasound catheter to transducer |
US7063679B2 (en) | 2002-09-20 | 2006-06-20 | Flowmedica, Inc. | Intra-aortic renal delivery catheter |
US7282213B2 (en) | 2002-09-30 | 2007-10-16 | Medtronic, Inc. | Method for applying a drug coating to a medical device |
EP1405613B1 (en) | 2002-10-04 | 2006-03-22 | Sorin Biomedica Cardio S.R.L. | An implant device for treating aneurisms of the abdominal aorta |
US6673101B1 (en) | 2002-10-09 | 2004-01-06 | Endovascular Technologies, Inc. | Apparatus and method for deploying self-expanding stents |
US7493154B2 (en) | 2002-10-23 | 2009-02-17 | Medtronic, Inc. | Methods and apparatus for locating body vessels and occlusions in body vessels |
US6936003B2 (en) * | 2002-10-29 | 2005-08-30 | Given Imaging Ltd | In-vivo extendable element device and system, and method of use |
US20040088011A1 (en) * | 2002-10-31 | 2004-05-06 | Koninklijke Philips Electronics N.V. | Defibrillation circuit that can compensate for a variation in a patient parameter and related defibrillator and method |
US7404824B1 (en) | 2002-11-15 | 2008-07-29 | Advanced Cardiovascular Systems, Inc. | Valve aptation assist device |
US7599730B2 (en) | 2002-11-19 | 2009-10-06 | Medtronic Navigation, Inc. | Navigation system for cardiac therapies |
US6926713B2 (en) | 2002-12-11 | 2005-08-09 | Boston Scientific Scimed, Inc. | Angle indexer for medical devices |
KR100887669B1 (ko) | 2002-12-28 | 2009-03-11 | 엘지디스플레이 주식회사 | 액정표시장치 및 그 제조방법 |
US20050154277A1 (en) | 2002-12-31 | 2005-07-14 | Jing Tang | Apparatus and methods of using built-in micro-spectroscopy micro-biosensors and specimen collection system for a wireless capsule in a biological body in vivo |
EP1583569A4 (en) | 2003-01-03 | 2009-05-06 | Ekos Corp | ULTRASONIC CATHETER COMPRISING AN AXIAL ENERGY FIELD |
US6847848B2 (en) | 2003-01-07 | 2005-01-25 | Mmtc, Inc | Inflatable balloon catheter structural designs and methods for treating diseased tissue of a patient |
US7083612B2 (en) | 2003-01-15 | 2006-08-01 | Cryodynamics, Llc | Cryotherapy system |
US7087051B2 (en) | 2003-01-15 | 2006-08-08 | Boston Scientific Scimed, Inc. | Articulating radio frequency probe handle |
US7819866B2 (en) | 2003-01-21 | 2010-10-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation catheter and electrode |
US6960207B2 (en) | 2003-01-21 | 2005-11-01 | St Jude Medical, Daig Division, Inc. | Ablation catheter having a virtual electrode comprising portholes and a porous conductor |
JP4067976B2 (ja) | 2003-01-24 | 2008-03-26 | 有限会社日本エレクテル | 高周波加温バルーンカテーテル |
JP2006517827A (ja) | 2003-01-29 | 2006-08-03 | イー−ピル・ファーマ・リミテッド | 胃腸管内における活性薬物の送達 |
US20040193211A1 (en) | 2003-02-14 | 2004-09-30 | Voegele James W. | Fingertip surgical instruments |
US7201749B2 (en) | 2003-02-19 | 2007-04-10 | Biosense, Inc. | Externally-applied high intensity focused ultrasound (HIFU) for pulmonary vein isolation |
CN1764419A (zh) | 2003-02-20 | 2006-04-26 | 普罗里森姆股份有限公司 | 心脏消融装置 |
US8465452B2 (en) | 2003-02-21 | 2013-06-18 | 3Dt Holdings, Llc | Devices, systems, and methods for removing stenotic lesions from vessels |
US7818053B2 (en) | 2003-02-21 | 2010-10-19 | Dtherapeutics, Llc | Devices, systems and methods for plaque type determination |
US9603545B2 (en) | 2003-02-21 | 2017-03-28 | 3Dt Holdings, Llc | Devices, systems, and methods for removing targeted lesions from vessels |
US6923808B2 (en) | 2003-02-24 | 2005-08-02 | Boston Scientific Scimed, Inc. | Probes having helical and loop shaped inflatable therapeutic elements |
US20040167506A1 (en) | 2003-02-25 | 2004-08-26 | Scimed Life Systems, Inc. | Medical devices employing ferromagnetic heating |
US7314480B2 (en) | 2003-02-27 | 2008-01-01 | Boston Scientific Scimed, Inc. | Rotating balloon expandable sheath bifurcation delivery |
DE10308383A1 (de) | 2003-02-27 | 2004-09-16 | Storz Endoskop Produktions Gmbh | Verfahren und optisches System zur Vermessung der Topographie eines Meßobjekts |
US7250041B2 (en) | 2003-03-12 | 2007-07-31 | Abbott Cardiovascular Systems Inc. | Retrograde pressure regulated infusion |
US20050015125A1 (en) | 2003-03-14 | 2005-01-20 | Mioduski Paul C. | Hyperthermia treatment systems and methods |
US7792568B2 (en) | 2003-03-17 | 2010-09-07 | Boston Scientific Scimed, Inc. | MRI-visible medical devices |
US7972330B2 (en) | 2003-03-27 | 2011-07-05 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US8021362B2 (en) | 2003-03-27 | 2011-09-20 | Terumo Kabushiki Kaisha | Methods and apparatus for closing a layered tissue defect |
US7293562B2 (en) | 2003-03-27 | 2007-11-13 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
US20040206365A1 (en) * | 2003-03-31 | 2004-10-21 | Knowlton Edward Wells | Method for treatment of tissue |
US6953425B2 (en) | 2003-04-25 | 2005-10-11 | Medtronic Vascular, Inc. | Method of treating vulnerable plaque using a catheter-based radiation system |
US7597704B2 (en) | 2003-04-28 | 2009-10-06 | Atritech, Inc. | Left atrial appendage occlusion device with active expansion |
US20040243022A1 (en) | 2003-04-29 | 2004-12-02 | Medtronic Vascular, Inc. | Method and system of detecting vulnerable plaque by sensing motion of thin fibrous cap |
JP4850697B2 (ja) | 2003-05-02 | 2012-01-11 | ボストン サイエンティフィック リミテッド | 多機能医療用カテーテル |
US7279600B2 (en) | 2003-05-02 | 2007-10-09 | Wyeth | Hydroxy-biphenyl-carbaldehyde oxime derivatives and their use as estrogenic agents |
CL2004000985A1 (es) | 2003-05-16 | 2005-01-14 | Wyeth Corp | Compuestos derivados de fenilquinolinas; composicion farmaceutica, proceso de preparacion; y uso para tratar osteoporosis, enfermedad de paget, dano vascular, osteoartritis, cancer oseo, cancer ovarico, cancer prostatico, hipercolesterolemia, aterosc |
JP2004337400A (ja) | 2003-05-16 | 2004-12-02 | Terumo Corp | 薬剤投与キット |
ATE350366T1 (de) | 2003-05-16 | 2007-01-15 | Wyeth Corp | Aryl-carbaldehyd oxime-verbindungen und deren verwendung als oestrogenwirksame substanzen |
US7758520B2 (en) | 2003-05-27 | 2010-07-20 | Boston Scientific Scimed, Inc. | Medical device having segmented construction |
WO2004105807A2 (en) | 2003-05-27 | 2004-12-09 | Venture Manufacturing, Llc | Balloon centered radially expanding ablation device |
US6932776B2 (en) | 2003-06-02 | 2005-08-23 | Meridian Medicalssystems, Llc | Method and apparatus for detecting and treating vulnerable plaques |
JP4616252B2 (ja) | 2003-06-04 | 2011-01-19 | シネコー・エルエルシー | 脈管内電気生理システム及び方法 |
US7738952B2 (en) | 2003-06-09 | 2010-06-15 | Palo Alto Investors | Treatment of conditions through modulation of the autonomic nervous system |
WO2004110258A2 (en) | 2003-06-10 | 2004-12-23 | Cardiofocus, Inc. | Guided cardiac ablation catheters |
US20080208169A1 (en) | 2003-06-11 | 2008-08-28 | Boyle Edward M Jr | Body-Space Treatment Catheter |
US7112196B2 (en) | 2003-06-13 | 2006-09-26 | Piezo Technologies, Inc. | Multi-element array for acoustic ablation |
DE10328816A1 (de) | 2003-06-21 | 2005-01-05 | Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin | Implantierbare Stimulationselektrode mit einer Beschichtung zur Erhöhung der Gewebsverträglichkeit |
US7066895B2 (en) | 2003-06-30 | 2006-06-27 | Ethicon, Inc. | Ultrasonic radial focused transducer for pulmonary vein ablation |
US7678104B2 (en) | 2003-07-17 | 2010-03-16 | Biosense Webster, Inc. | Ultrasound ablation catheter and method for its use |
US7670335B2 (en) | 2003-07-21 | 2010-03-02 | Biosense Webster, Inc. | Ablation device with spiral array ultrasound transducer |
US7479157B2 (en) | 2003-08-07 | 2009-01-20 | Boston Scientific Scimed, Inc. | Stent designs which enable the visibility of the inside of the stent during MRI |
US7250440B2 (en) | 2003-08-12 | 2007-07-31 | Wyeth | (Hydroxyphenyl)-1H-indole-3-carbaldehyde oxime derivatives as estrogenic agents |
US7294125B2 (en) | 2003-08-22 | 2007-11-13 | Scimed Life Systems, Inc. | Methods of delivering energy to body portions to produce a therapeutic response |
US7313430B2 (en) | 2003-08-28 | 2007-12-25 | Medtronic Navigation, Inc. | Method and apparatus for performing stereotactic surgery |
CA2938411C (en) | 2003-09-12 | 2019-03-05 | Minnow Medical, Llc | Selectable eccentric remodeling and/or ablation of atherosclerotic material |
US7569052B2 (en) | 2003-09-12 | 2009-08-04 | Boston Scientific Scimed, Inc. | Ablation catheter with tissue protecting assembly |
US7736362B2 (en) | 2003-09-15 | 2010-06-15 | Boston Scientific Scimed, Inc. | Catheter balloons |
US7758510B2 (en) | 2003-09-19 | 2010-07-20 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
US7435248B2 (en) | 2003-09-26 | 2008-10-14 | Boston Scientific Scimed, Inc. | Medical probes for creating and diagnosing circumferential lesions within or around the ostium of a vessel |
WO2005037070A2 (en) | 2003-10-11 | 2005-04-28 | The Regents Of The University Of California | Method and system for nerve repair, nanoknife, mems platform and uses thereof |
US7280863B2 (en) | 2003-10-20 | 2007-10-09 | Magnetecs, Inc. | System and method for radar-assisted catheter guidance and control |
US7480532B2 (en) | 2003-10-22 | 2009-01-20 | Cvrx, Inc. | Baroreflex activation for pain control, sedation and sleep |
KR100573976B1 (ko) | 2003-10-28 | 2006-04-26 | 삼성전자주식회사 | 전사벨트의 구동방법 |
CA2544416A1 (en) | 2003-11-03 | 2005-05-12 | B-Balloon Ltd. | Treatment of vascular bifurcations |
EP1689457A2 (en) | 2003-11-10 | 2006-08-16 | Angiotech International Ag | Intravascular devices and fibrosis-inducing agents |
WO2005065079A2 (en) | 2003-11-10 | 2005-07-21 | Angiotech International Ag | Medical implants and fibrosis-inducing agents |
AU2004291062A1 (en) | 2003-11-10 | 2005-06-02 | Angiotech International Ag | Medical implants and anti-scarring agents |
US7367970B2 (en) | 2003-11-11 | 2008-05-06 | Biosense Webster Inc. | Externally applied RF for pulmonary vein isolation |
WO2005051224A2 (en) | 2003-11-25 | 2005-06-09 | F.D. Cardio Ltd. | Stent positioning using inflation tube |
WO2005053555A1 (de) | 2003-12-01 | 2005-06-16 | Biotronik Crm Patent Ag | Elektrodenleitung für die elektrotherapie von herzgewebe |
US8336705B2 (en) | 2003-12-02 | 2012-12-25 | Fuso Pharmaceuticals Industries, Ltd. | Multi-chamber container |
JP4391221B2 (ja) | 2003-12-22 | 2009-12-24 | 有限会社日本エレクテル | 高周波加温バルーンカテーテル |
US20050148842A1 (en) | 2003-12-22 | 2005-07-07 | Leming Wang | Positioning devices and methods for in vivo wireless imaging capsules |
US7686841B2 (en) | 2003-12-29 | 2010-03-30 | Boston Scientific Scimed, Inc. | Rotating balloon expandable sheath bifurcation delivery system |
WO2005065559A1 (ja) | 2004-01-06 | 2005-07-21 | Toray Industries, Inc. | バルーンカテーテル |
US7326206B2 (en) | 2004-01-16 | 2008-02-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Conforming-electrode catheter and method for ablation |
US7371231B2 (en) | 2004-02-02 | 2008-05-13 | Boston Scientific Scimed, Inc. | System and method for performing ablation using a balloon |
KR100605849B1 (ko) | 2004-02-09 | 2006-08-01 | 삼성전자주식회사 | 휴대용 단말기의 데이터 저장 및 재생방법 |
US20050182479A1 (en) | 2004-02-13 | 2005-08-18 | Craig Bonsignore | Connector members for stents |
US7157492B2 (en) | 2004-02-26 | 2007-01-02 | Wyeth | Dibenzo chromene derivatives and their use as ERβ selective ligands |
US20050203410A1 (en) | 2004-02-27 | 2005-09-15 | Ep Medsystems, Inc. | Methods and systems for ultrasound imaging of the heart from the pericardium |
US7198632B2 (en) | 2004-03-02 | 2007-04-03 | Boston Scientific Scimed, Inc. | Occlusion balloon catheter with longitudinally expandable balloon |
US7662114B2 (en) | 2004-03-02 | 2010-02-16 | Focus Surgery, Inc. | Ultrasound phased arrays |
US8052636B2 (en) | 2004-03-05 | 2011-11-08 | Hansen Medical, Inc. | Robotic catheter system and methods |
US7247141B2 (en) | 2004-03-08 | 2007-07-24 | Ethicon Endo-Surgery, Inc. | Intra-cavitary ultrasound medical system and method |
US7238184B2 (en) | 2004-03-15 | 2007-07-03 | Boston Scientific Scimed, Inc. | Ablation probe with peltier effect thermal control |
US20050228415A1 (en) | 2004-03-23 | 2005-10-13 | Michael Gertner | Methods and devices for percutaneous, non-laparoscopic treatment of obesity |
US20080147002A1 (en) | 2004-03-23 | 2008-06-19 | Michael Eric Gertner | Obesity treatment systems |
US7946976B2 (en) | 2004-03-23 | 2011-05-24 | Michael Gertner | Methods and devices for the surgical creation of satiety and biofeedback pathways |
US8001976B2 (en) | 2004-03-23 | 2011-08-23 | Michael Gertner | Management systems for the surgically treated obese patient |
US20080071306A1 (en) | 2004-03-23 | 2008-03-20 | Michael Gertner | Extragastric Balloon With Attachment Tabs |
US7841978B2 (en) | 2004-03-23 | 2010-11-30 | Michael Gertner | Methods and devices for to treatment of obesity |
US20080300618A1 (en) | 2004-03-23 | 2008-12-04 | Michael Eric Gertner | Obesity treatment systems |
WO2006049725A2 (en) | 2004-03-23 | 2006-05-11 | Minimus Surgical Systems | Surgical systems and devices to enhance gastric restriction therapies |
US20070233170A1 (en) | 2004-03-23 | 2007-10-04 | Michael Gertner | Extragastric Balloon |
US8343031B2 (en) | 2004-03-23 | 2013-01-01 | Michael Gertner | Obesity treatment systems |
US20060195139A1 (en) | 2004-03-23 | 2006-08-31 | Michael Gertner | Extragastric devices and methods for gastroplasty |
US9555223B2 (en) | 2004-03-23 | 2017-01-31 | Medtronic Cryocath Lp | Method and apparatus for inflating and deflating balloon catheters |
US7255675B2 (en) | 2004-03-23 | 2007-08-14 | Michael Gertner | Devices and methods to treat a patient |
US20060142790A1 (en) | 2004-03-23 | 2006-06-29 | Michael Gertner | Methods and devices to facilitate connections between body lumens |
US7854733B2 (en) | 2004-03-24 | 2010-12-21 | Biosense Webster, Inc. | Phased-array for tissue treatment |
US20050214268A1 (en) | 2004-03-25 | 2005-09-29 | Cavanagh William A Iii | Methods for treating tumors and cancerous tissues |
JP4216810B2 (ja) | 2004-03-30 | 2009-01-28 | 株式会社東芝 | 生体情報計測装置 |
US7323006B2 (en) | 2004-03-30 | 2008-01-29 | Xtent, Inc. | Rapid exchange interventional devices and methods |
US20050228286A1 (en) | 2004-04-07 | 2005-10-13 | Messerly Jeffrey D | Medical system having a rotatable ultrasound source and a piercing tip |
US20060018949A1 (en) | 2004-04-07 | 2006-01-26 | Bausch & Lomb Incorporated | Injectable biodegradable drug delivery system |
US20060004323A1 (en) | 2004-04-21 | 2006-01-05 | Exploramed Nc1, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
US7566319B2 (en) | 2004-04-21 | 2009-07-28 | Boston Scientific Scimed, Inc. | Traction balloon |
US20050245862A1 (en) | 2004-04-28 | 2005-11-03 | Endobionics, Inc. | Torque mechanism for interventional catheters |
US20050251116A1 (en) | 2004-05-05 | 2005-11-10 | Minnow Medical, Llc | Imaging and eccentric atherosclerotic material laser remodeling and/or ablation catheter |
US7291142B2 (en) | 2004-05-10 | 2007-11-06 | Boston Scientific Scimed, Inc. | Low temperature lesion formation apparatus, systems and methods |
US7087053B2 (en) | 2004-05-27 | 2006-08-08 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Catheter with bifurcated, collapsible tip for sensing and ablating |
WO2005117758A1 (en) | 2004-05-28 | 2005-12-15 | Cook Incorporated | Exchangeable delivery system for expandable prosthetic devices |
US20050267556A1 (en) | 2004-05-28 | 2005-12-01 | Allan Shuros | Drug eluting implants to prevent cardiac apoptosis |
WO2005120375A2 (en) | 2004-06-02 | 2005-12-22 | Medtronic, Inc. | Loop ablation apparatus and method |
US20050273149A1 (en) | 2004-06-08 | 2005-12-08 | Tran Thomas T | Bifurcated stent delivery system |
US7640046B2 (en) | 2004-06-18 | 2009-12-29 | Cardiac Pacemakers, Inc. | Methods and apparatuses for localizing myocardial infarction during catheterization |
US7197354B2 (en) | 2004-06-21 | 2007-03-27 | Mediguide Ltd. | System for determining the position and orientation of a catheter |
US7367975B2 (en) | 2004-06-21 | 2008-05-06 | Cierra, Inc. | Energy based devices and methods for treatment of anatomic tissue defects |
US20060024564A1 (en) | 2004-07-06 | 2006-02-02 | Manclaw Ronald R | Manclaw-Harrison fuel cell |
US20060025765A1 (en) | 2004-07-30 | 2006-02-02 | Jaime Landman | Electrosurgical systems and methods |
US7799021B2 (en) | 2004-08-04 | 2010-09-21 | Kimberly-Clark Inc. | Electrosurgical treatment in conjunction with monitoring |
EP2319925B1 (en) | 2004-08-16 | 2018-07-25 | Quark Pharmaceuticals, Inc. | Therapeutic uses of inhibitors of RTP801 |
US7540852B2 (en) | 2004-08-26 | 2009-06-02 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
CN101052641A (zh) | 2004-09-07 | 2007-10-10 | 惠氏公司 | 6H-[1]苯并吡喃并[4,3-b]喹啉及其作为雌激素药物的用途 |
US20060085054A1 (en) | 2004-09-09 | 2006-04-20 | Zikorus Arthur W | Methods and apparatus for treatment of hollow anatomical structures |
US20060095096A1 (en) | 2004-09-09 | 2006-05-04 | Debenedictis Leonard C | Interchangeable tips for medical laser treatments and methods for using same |
US8396548B2 (en) | 2008-11-14 | 2013-03-12 | Vessix Vascular, Inc. | Selective drug delivery in a lumen |
US9974607B2 (en) | 2006-10-18 | 2018-05-22 | Vessix Vascular, Inc. | Inducing desirable temperature effects on body tissue |
US8545488B2 (en) | 2004-09-17 | 2013-10-01 | The Spectranetics Corporation | Cardiovascular imaging system |
US7458971B2 (en) | 2004-09-24 | 2008-12-02 | Boston Scientific Scimed, Inc. | RF ablation probe with unibody electrode element |
US7635383B2 (en) | 2004-09-28 | 2009-12-22 | Boston Scientific Scimed, Inc. | Rotating stent delivery system for side branch access and protection and method of using same |
US20060069385A1 (en) | 2004-09-28 | 2006-03-30 | Scimed Life Systems, Inc. | Methods and apparatus for tissue cryotherapy |
WO2006042047A1 (en) | 2004-10-07 | 2006-04-20 | Flea Street Translational, Llc | Methods, systems and devices for establishing communication between hollow organs and tissue lumens |
US20060089637A1 (en) | 2004-10-14 | 2006-04-27 | Werneth Randell L | Ablation catheter |
US7887538B2 (en) | 2005-10-15 | 2011-02-15 | Baxano, Inc. | Methods and apparatus for tissue modification |
US7938830B2 (en) | 2004-10-15 | 2011-05-10 | Baxano, Inc. | Powered tissue modification devices and methods |
US20060083194A1 (en) | 2004-10-19 | 2006-04-20 | Ardian Dhrimaj | System and method rendering audio/image data on remote devices |
US7962854B2 (en) | 2004-10-19 | 2011-06-14 | Sony Ericsson Mobile Communications Ab | Systems, methods and computer program products for displaying content on multiple display screens using handheld wireless communicators |
WO2006049970A2 (en) | 2004-10-27 | 2006-05-11 | Yuval Carmel | Radio-frequency device for passivation of vascular plaque and method of using same |
US7753907B2 (en) | 2004-10-29 | 2010-07-13 | Boston Scientific Scimed, Inc. | Medical device systems and methods |
US7937143B2 (en) | 2004-11-02 | 2011-05-03 | Ardian, Inc. | Methods and apparatus for inducing controlled renal neuromodulation |
US7200445B1 (en) | 2005-10-21 | 2007-04-03 | Asthmatx, Inc. | Energy delivery devices and methods |
US20090240249A1 (en) | 2004-11-08 | 2009-09-24 | Cardima, Inc. | System and Method for Performing Ablation and Other Medical Procedures Using An Electrode Array with Flexible Circuit |
US8617152B2 (en) | 2004-11-15 | 2013-12-31 | Medtronic Ablation Frontiers Llc | Ablation system with feedback |
US20060129128A1 (en) | 2004-11-15 | 2006-06-15 | Sampson Russel M | Method and system for drug delivery |
CA2587780A1 (en) | 2004-11-18 | 2006-05-26 | Transpharma Medical Ltd. | Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents |
US20060167106A1 (en) | 2004-11-19 | 2006-07-27 | Mei Zhang | Compounds acting at the centrosome |
US7473890B2 (en) | 2004-11-23 | 2009-01-06 | New York University | Manipulation of objects in potential energy landscapes |
US20060247266A1 (en) | 2004-11-26 | 2006-11-02 | Asahi Kasei Pharma Corporation | Nitrogen-containing tricyclic compounds |
US8048144B2 (en) | 2004-11-30 | 2011-11-01 | Scimed Life Systems, Inc. | Prosthesis fixation device and method |
EP1819304B1 (en) | 2004-12-09 | 2023-01-25 | Twelve, Inc. | Aortic valve repair |
US7402151B2 (en) | 2004-12-17 | 2008-07-22 | Biocardia, Inc. | Steerable guide catheters and methods for their use |
WO2006066610A1 (en) | 2004-12-23 | 2006-06-29 | Telecom Italia S.P.A. | Method and system for video telephone communications set up, related equipment and computer program product |
US20080009927A1 (en) | 2005-01-11 | 2008-01-10 | Vilims Bradley D | Combination Electrical Stimulating and Infusion Medical Device and Method |
US8007440B2 (en) | 2005-02-08 | 2011-08-30 | Volcano Corporation | Apparatus and methods for low-cost intravascular ultrasound imaging and for crossing severe vascular occlusions |
US7828837B2 (en) | 2005-02-17 | 2010-11-09 | Khoury Medical Devices, LLC. | Vascular endograft |
US20060182873A1 (en) | 2005-02-17 | 2006-08-17 | Klisch Leo M | Medical devices |
US7515965B2 (en) * | 2005-02-23 | 2009-04-07 | Medtronic, Inc. | Implantable medical device providing adaptive neurostimulation therapy for incontinence |
PT1853271E (pt) | 2005-03-04 | 2011-01-28 | Sucampo Ag | Método e composição para o tratamento de doenças vasculares periféricas |
US8801701B2 (en) | 2005-03-09 | 2014-08-12 | Sunnybrook Health Sciences Centre | Method and apparatus for obtaining quantitative temperature measurements in prostate and other tissue undergoing thermal therapy treatment |
US7759315B2 (en) | 2005-03-09 | 2010-07-20 | Csl Behring Ag | Treatment of inflammatory conditions of the intestine |
US7674256B2 (en) | 2005-03-17 | 2010-03-09 | Boston Scientific Scimed, Inc. | Treating internal body tissue |
ATE533520T1 (de) | 2005-03-23 | 2011-12-15 | Abbott Lab | Abgabe von stark lipophilen mitteln durch medizinprodukte |
US7670337B2 (en) | 2005-03-25 | 2010-03-02 | Boston Scientific Scimed, Inc. | Ablation probe having a plurality of arrays of electrodes |
ES2565342T3 (es) | 2005-03-28 | 2016-04-04 | Vessix Vascular, Inc. | Caracterización eléctrica intraluminal de tejido y energía de RF regulada para tratamiento selectivo de ateroma y otros tejidos diana |
US20060224153A1 (en) | 2005-04-05 | 2006-10-05 | Fischell Robert E | Catheter system for the treatment of atrial fibrillation |
US7715912B2 (en) | 2005-04-13 | 2010-05-11 | Intelect Medical, Inc. | System and method for providing a waveform for stimulating biological tissue |
EP3804647A1 (en) | 2005-04-21 | 2021-04-14 | Boston Scientific Scimed Inc. | Control methods and devices for energy delivery |
US20060239921A1 (en) | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
US7505816B2 (en) | 2005-04-29 | 2009-03-17 | Medtronic, Inc. | Actively cooled external energy source, external charger, system of transcutaneous energy transfer, system of transcutaneous charging and method therefore |
US20060247760A1 (en) | 2005-04-29 | 2006-11-02 | Medtronic Vascular, Inc. | Methods and apparatus for treatment of aneurysms adjacent branch arteries |
US7806871B2 (en) | 2005-05-09 | 2010-10-05 | Boston Scientific Scimed, Inc. | Method and device for tissue removal and for delivery of a therapeutic agent or bulking agent |
US20080161717A1 (en) | 2005-05-10 | 2008-07-03 | Michael Eric Gertner | Obesity Treatment Systems |
US7862565B2 (en) | 2005-05-12 | 2011-01-04 | Aragon Surgical, Inc. | Method for tissue cauterization |
US20080091193A1 (en) | 2005-05-16 | 2008-04-17 | James Kauphusman | Irrigated ablation catheter having magnetic tip for magnetic field control and guidance |
KR20120099730A (ko) | 2005-05-20 | 2012-09-11 | 오메로스 코포레이션 | 시클로옥시게나제 저해제 및 칼슘채널 길항제 조성물 및 이의 비뇨기과 시술시의 용도를 위한 방법 |
US10092429B2 (en) | 2005-08-22 | 2018-10-09 | Incept, Llc | Flared stents and apparatus and methods for delivering them |
US7767844B2 (en) | 2005-05-23 | 2010-08-03 | Atomic Energy Council | Method for manufacturing diethylene triamine pentaacetic acid derivative |
US8951225B2 (en) | 2005-06-10 | 2015-02-10 | Acclarent, Inc. | Catheters with non-removable guide members useable for treatment of sinusitis |
US7584004B2 (en) | 2005-06-13 | 2009-09-01 | Cardiac Pacemakers, Inc. | Vascularly stabilized peripheral nerve cuff assembly |
EP2759276A1 (en) | 2005-06-20 | 2014-07-30 | Medtronic Ablation Frontiers LLC | Ablation catheter |
US7717853B2 (en) | 2005-06-24 | 2010-05-18 | Henry Nita | Methods and apparatus for intracranial ultrasound delivery |
CA2613671C (en) | 2005-06-29 | 2014-04-08 | Radiant Medical, Inc. | Devices, systems and methods for rapid endovascular cooling |
US20070016274A1 (en) | 2005-06-29 | 2007-01-18 | Boveja Birinder R | Gastrointestinal (GI) ablation for GI tumors or to provide therapy for obesity, motility disorders, G.E.R.D., or to induce weight loss |
WO2007005386A1 (en) | 2005-06-30 | 2007-01-11 | Rox Medical, Inc. | Devices, systems, and methods for creation of a peripherally located fistula |
DE102005032755B4 (de) | 2005-07-13 | 2014-09-04 | Siemens Aktiengesellschaft | System zur Durchführung und Überwachung minimal-invasiver Eingriffe |
US20070016184A1 (en) | 2005-07-14 | 2007-01-18 | Ethicon Endo-Surgery, Inc. | Medical-treatment electrode assembly and method for medical treatment |
EP1906853B1 (en) | 2005-07-21 | 2017-09-06 | Covidien LP | Systems for treating a hollow anatomical structure |
EP1909694B1 (en) | 2005-07-25 | 2014-06-11 | Rainbow Medical Ltd. | Electrical stimulation of blood vessels |
CA2616760C (en) | 2005-07-26 | 2014-10-07 | Rox Medical, Inc. | Devices, systems, and methods for peripheral arteriovenous fistula creation |
US7983751B2 (en) | 2005-08-12 | 2011-07-19 | Proteus Biomedical, Inc. | Measuring conduction velocity using one or more satellite devices |
US7591996B2 (en) | 2005-08-17 | 2009-09-22 | University Of Washington | Ultrasound target vessel occlusion using microbubbles |
DE102005041601B4 (de) | 2005-09-01 | 2010-07-08 | Siemens Ag | Ablationskatheter zum Setzen einer Läsion und Verfahren zur Herstellung eines Ablationskatheters |
EP1934289A4 (en) | 2005-09-09 | 2011-07-20 | Ottawa Health Research Inst | INTERPENDENT NETWORKS AND RELATED METHODS AND COMPOSITIONS |
US20070073151A1 (en) | 2005-09-13 | 2007-03-29 | General Electric Company | Automated imaging and therapy system |
WO2007041593A2 (en) | 2005-10-03 | 2007-04-12 | Combinatorx, Incorporated | Anti-scarring drug combinations and use thereof |
US20070299043A1 (en) | 2005-10-03 | 2007-12-27 | Hunter William L | Anti-scarring drug combinations and use thereof |
DE102005050344A1 (de) | 2005-10-20 | 2007-05-03 | Siemens Ag | Kryokatheter zur Einführung in ein Körpergefäß sowie medizinische Untersuchungs- und Behandlungsvorrichtung |
US20070093697A1 (en) | 2005-10-21 | 2007-04-26 | Theranova, Llc | Method and apparatus for detection of right to left shunting in the cardiopulmonary vasculature |
US8257338B2 (en) | 2006-10-27 | 2012-09-04 | Artenga, Inc. | Medical microbubble generation |
US9061146B2 (en) * | 2005-10-28 | 2015-06-23 | Medtronic, Inc. | Impedance-based bladder sensing |
JP4702704B2 (ja) | 2005-11-01 | 2011-06-15 | 有限会社日本エレクテル | バルーンカテーテルシステム |
US7901420B2 (en) | 2005-11-02 | 2011-03-08 | University Of Massachusetts | Tissue clamp |
US8052700B2 (en) | 2005-11-02 | 2011-11-08 | University Of Massachusetts | Tissue clamp |
US10716749B2 (en) | 2005-11-03 | 2020-07-21 | Palo Alto Investors | Methods and compositions for treating a renal disease condition in a subject |
US20080249525A1 (en) | 2005-11-08 | 2008-10-09 | U & I Corporation | Radio Frequency Ablation Electrode for Selected Tissue Removal |
US7766833B2 (en) | 2005-11-23 | 2010-08-03 | General Electric Company | Ablation array having independently activated ablation elements |
US7959627B2 (en) | 2005-11-23 | 2011-06-14 | Barrx Medical, Inc. | Precision ablating device |
US8190238B2 (en) | 2005-12-09 | 2012-05-29 | Hansen Medical, Inc. | Robotic catheter system and methods |
US7776967B2 (en) | 2005-12-16 | 2010-08-17 | Continental Ag | Polyorganosiloxane composition for use in unsaturated elastomer, article made therefrom, and associated method |
US20080108867A1 (en) | 2005-12-22 | 2008-05-08 | Gan Zhou | Devices and Methods for Ultrasonic Imaging and Ablation |
US8031927B2 (en) | 2005-12-28 | 2011-10-04 | The General Hospital Corporation | Medical image processing |
US7896874B2 (en) | 2005-12-29 | 2011-03-01 | Boston Scientific Scimed, Inc. | RF ablation probes with tine valves |
US7993334B2 (en) | 2005-12-29 | 2011-08-09 | Boston Scientific Scimed, Inc. | Low-profile, expanding single needle ablation probe |
US8033284B2 (en) | 2006-01-11 | 2011-10-11 | Curaelase, Inc. | Therapeutic laser treatment |
US20070162109A1 (en) | 2006-01-11 | 2007-07-12 | Luis Davila | Intraluminal stent graft |
WO2007143281A2 (en) | 2006-01-13 | 2007-12-13 | Mirabilis Medica Inc. | Methods and apparatus for the treatment of menometrorrhagia, endometrial pathology, and cervical neoplasia using high intensity focused ultrasound energy |
CA2574935A1 (en) | 2006-01-24 | 2007-07-24 | Sherwood Services Ag | A method and system for controlling an output of a radio-frequency medical generator having an impedance based control algorithm |
US20070179496A1 (en) | 2006-01-31 | 2007-08-02 | Medtronic, Inc. | Flexible catheter for ablation therapy |
EP1988941A2 (en) | 2006-01-31 | 2008-11-12 | Nanocopoeia, Inc. | Nanoparticle coating of surfaces |
CA2637787A1 (en) | 2006-02-03 | 2007-08-16 | Synecor, Llc | Intravascular device for neuromodulation |
US7918850B2 (en) | 2006-02-17 | 2011-04-05 | Biosense Wabster, Inc. | Lesion assessment by pacing |
US7869854B2 (en) | 2006-02-23 | 2011-01-11 | Magnetecs, Inc. | Apparatus for magnetically deployable catheter with MOSFET sensor and method for mapping and ablation |
US20070208210A1 (en) | 2006-03-02 | 2007-09-06 | G&L Consulting, Llc | Method and apparatus to unload a failing heart |
US8043673B2 (en) | 2006-03-02 | 2011-10-25 | Boston Scientific Scimed, Inc. | Method to make tube-in-tube balloon |
US20070208256A1 (en) | 2006-03-03 | 2007-09-06 | Medtronic Vascular, Inc. | Multiple Branch Tubular Prosthesis and Methods |
US8585753B2 (en) | 2006-03-04 | 2013-11-19 | John James Scanlon | Fibrillated biodegradable prosthesis |
US8027718B2 (en) | 2006-03-07 | 2011-09-27 | Mayo Foundation For Medical Education And Research | Regional anesthetic |
US7894905B2 (en) | 2006-03-13 | 2011-02-22 | Neuropace, Inc. | Implantable system enabling responsive therapy for pain |
US20070219576A1 (en) | 2006-03-16 | 2007-09-20 | Medtronic Vascular, Inc. | Reversibly and Radially Expandable Electroactive Polymer Element for Temporary Occlusion of a Vessel |
US7736360B2 (en) | 2006-03-17 | 2010-06-15 | Microcube, Llc | Devices and methods for creating continuous lesions |
US20070225781A1 (en) | 2006-03-21 | 2007-09-27 | Nidus Medical, Llc | Apparatus and methods for altering temperature in a region within the body |
EP2010085A1 (en) | 2006-03-31 | 2009-01-07 | Breval S.R.L. | Device and method for the thermal ablation of tumors by means of high-frequency electromagnetic energy under overpressure conditions |
US20080004673A1 (en) | 2006-04-03 | 2008-01-03 | Cvrx, Inc. | Implantable extravascular electrostimulation system having a resilient cuff |
JP2009533126A (ja) | 2006-04-14 | 2009-09-17 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | レーザ誘起光学破壊(liob)を使用する心臓アブレーション用システム及び方法 |
US20080051454A1 (en) | 2006-04-21 | 2008-02-28 | The Board Of Trustees Operating Michigan State University | Compositions and methods for transient receptor potential vanilloid (TRPV) channel mediated treatments |
US8019435B2 (en) | 2006-05-02 | 2011-09-13 | Boston Scientific Scimed, Inc. | Control of arterial smooth muscle tone |
US7511494B2 (en) | 2006-05-11 | 2009-03-31 | The General Hospital Corporation | Method for measuring the microarchitecture of complex tissue with MRI |
AU2007249248B2 (en) | 2006-05-12 | 2013-07-11 | Auris Health, Inc. | Device for ablating body tissue |
US7725157B2 (en) | 2006-05-16 | 2010-05-25 | General Electric Company | System and method for interventional procedures using MRI |
RU2008151150A (ru) | 2006-05-24 | 2010-06-27 | Эмсижен Лимитед (Gb) | Устройство для герметизации сосуда и способы герметизации |
US20080039746A1 (en) | 2006-05-25 | 2008-02-14 | Medtronic, Inc. | Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions |
WO2007140597A1 (en) | 2006-06-02 | 2007-12-13 | Victhom Human Bionics Inc. | Nerve cuff, method and apparatus for manufacturing same |
EP2026843A4 (en) | 2006-06-09 | 2011-06-22 | Quark Pharmaceuticals Inc | THERAPEUTIC USES OF RTP801L INHIBITORS |
US20080097251A1 (en) | 2006-06-15 | 2008-04-24 | Eilaz Babaev | Method and apparatus for treating vascular obstructions |
JP2008010537A (ja) | 2006-06-28 | 2008-01-17 | Toshiba Corp | Nand型不揮発性半導体記憶装置およびnand型不揮発性半導体記憶装置の製造方法 |
ATE494040T1 (de) | 2006-06-28 | 2011-01-15 | Ardian Inc | Systeme für wärmeinduzierte renale neuromodulation |
CA2552620C (en) | 2006-07-20 | 2014-07-15 | Ruggedcom Inc. | An anchoring member to facilitate fastening daughter boards to a mother board and a method for use |
GB0614557D0 (en) | 2006-07-21 | 2006-08-30 | Emcision Ltd | Tissue Ablator |
US8452988B2 (en) | 2006-07-24 | 2013-05-28 | Michael Sujue Wang | Secure data storage for protecting digital content |
EP2068740B1 (en) | 2006-07-28 | 2019-04-17 | Serene Medical, Inc. | Ablation apparatus and system to limit nerve conduction |
WO2008017080A2 (en) | 2006-08-03 | 2008-02-07 | Hansen Medical, Inc. | Systems for performing minimally invasive procedures |
US20090221955A1 (en) | 2006-08-08 | 2009-09-03 | Bacoustics, Llc | Ablative ultrasonic-cryogenic methods |
US20080039727A1 (en) | 2006-08-08 | 2008-02-14 | Eilaz Babaev | Ablative Cardiac Catheter System |
US8725225B2 (en) | 2006-08-10 | 2014-05-13 | University Of Rochester | Intraoperative imaging of renal cortical tumors and cysts |
US20080039830A1 (en) | 2006-08-14 | 2008-02-14 | Munger Gareth T | Method and Apparatus for Ablative Recanalization of Blocked Vasculature |
US20080243091A1 (en) | 2006-08-22 | 2008-10-02 | Mitchell R. Humphreys | Process and System For Systematic Oxygenation and Renal Preservation During Retrograde Perfusion of the Ischemic Kidney |
KR20090045940A (ko) | 2006-08-29 | 2009-05-08 | 포휴먼텍(주) | 세포자멸사의 억제를 위한 약학 조성물, 및 이를 전달하는 방법 |
US20080064957A1 (en) | 2006-09-07 | 2008-03-13 | Spence Paul A | Ultrasonic implant, systems and methods related to diverting material in blood flow away from the head |
US20080082109A1 (en) | 2006-09-08 | 2008-04-03 | Hansen Medical, Inc. | Robotic surgical system with forward-oriented field of view guide instrument navigation |
WO2008033867A2 (en) | 2006-09-11 | 2008-03-20 | Enbio Limited | Method of doping surfaces |
US8486060B2 (en) | 2006-09-18 | 2013-07-16 | Cytyc Corporation | Power ramping during RF ablation |
US20080071269A1 (en) | 2006-09-18 | 2008-03-20 | Cytyc Corporation | Curved Endoscopic Medical Device |
US7691080B2 (en) | 2006-09-21 | 2010-04-06 | Mercator Medsystems, Inc. | Dual modulus balloon for interventional procedures |
EP2267199A3 (en) | 2006-09-29 | 2012-09-12 | The University of Akron | Metal oxide fibers and nanofibers, method for making same, and uses thereof |
US8617149B2 (en) | 2006-10-02 | 2013-12-31 | Boston Scientific Scimed, Inc. | Common bond, double-balloon catheter |
US8641660B2 (en) | 2006-10-04 | 2014-02-04 | P Tech, Llc | Methods and devices for controlling biologic microenvironments |
US7664548B2 (en) | 2006-10-06 | 2010-02-16 | Cardiac Pacemakers, Inc. | Distributed neuromodulation system for treatment of cardiovascular disease |
US8388680B2 (en) | 2006-10-18 | 2013-03-05 | Guided Delivery Systems, Inc. | Methods and devices for catheter advancement and delivery of substances therethrough |
US7615072B2 (en) | 2006-11-14 | 2009-11-10 | Medtronic Vascular, Inc. | Endoluminal prosthesis |
US20080255550A1 (en) | 2006-11-30 | 2008-10-16 | Minos Medical | Systems and methods for less invasive neutralization by ablation of tissue including the appendix and gall bladder |
US20080140002A1 (en) | 2006-12-06 | 2008-06-12 | Kamal Ramzipoor | System for delivery of biologically active substances with actuating three dimensional surface |
US7699809B2 (en) | 2006-12-14 | 2010-04-20 | Urmey William F | Catheter positioning system |
US7846160B2 (en) | 2006-12-21 | 2010-12-07 | Cytyc Corporation | Method and apparatus for sterilization |
US7896871B2 (en) * | 2007-02-22 | 2011-03-01 | Medtronic, Inc. | Impedance computation for ablation therapy |
US20080208162A1 (en) | 2007-02-26 | 2008-08-28 | Joshi Ashok V | Device and Method For Thermophoretic Fluid Delivery |
US20080221448A1 (en) | 2007-03-07 | 2008-09-11 | Khuri-Yakub Butrus T | Image-guided delivery of therapeutic tools duing minimally invasive surgeries and interventions |
US8406877B2 (en) | 2007-03-19 | 2013-03-26 | Cardiac Pacemakers, Inc. | Selective nerve stimulation with optionally closed-loop capabilities |
US9486651B2 (en) | 2007-03-30 | 2016-11-08 | Koninklijke Philips N.V. | MRI-guided HIFU marking to guide radiotherapy and other procedures |
US8198611B2 (en) | 2007-04-02 | 2012-06-12 | Globalfoundries Inc. | Laser beam formatting module and method for fabricating semiconductor dies using same |
US9259233B2 (en) | 2007-04-06 | 2016-02-16 | Hologic, Inc. | Method and device for distending a gynecological cavity |
WO2008128070A2 (en) | 2007-04-11 | 2008-10-23 | The Cleveland Clinic Foundation | Method and apparatus for renal neuromodulation |
US8496653B2 (en) | 2007-04-23 | 2013-07-30 | Boston Scientific Scimed, Inc. | Thrombus removal |
US7495439B2 (en) | 2007-04-27 | 2009-02-24 | The General Hospital Corporation | MRI method for reducing artifacts using RF pulse at offset frequency |
US8641704B2 (en) | 2007-05-11 | 2014-02-04 | Medtronic Ablation Frontiers Llc | Ablation therapy system and method for treating continuous atrial fibrillation |
EP2164401B1 (en) | 2007-05-23 | 2015-08-26 | Medinol Ltd. | Apparatus for guided chronic total occlusion penetration |
US11395694B2 (en) | 2009-05-07 | 2022-07-26 | St. Jude Medical, Llc | Irrigated ablation catheter with multiple segmented ablation electrodes |
US20080312673A1 (en) | 2007-06-05 | 2008-12-18 | Viswanathan Raju R | Method and apparatus for CTO crossing |
US20090210953A1 (en) | 2007-06-08 | 2009-08-20 | Bryan Moyer | Identification of TRPML3 (MCOLN3) as a salty taste receptor and use in assays for identifying taste (salty) modulators and/or therapeutics that modulate sodium transport, absorption or excretion and/or aldosterone, and/or vasopressin production or release |
US8263104B2 (en) | 2007-06-08 | 2012-09-11 | Northwestern University | Polymer nanofilm coatings |
US20080312644A1 (en) | 2007-06-14 | 2008-12-18 | Boston Scientific Scimed, Inc. | Cryogenic balloon ablation instruments and systems |
US20090270850A1 (en) | 2007-06-20 | 2009-10-29 | Tea Time Partners, L.P., Organized In Texas | Devices and methods for the ablation of tissue in the lateral direction |
US20090018486A1 (en) | 2007-07-13 | 2009-01-15 | Menachem Goren | Diagnosis and treatment of vericocele and prostate disorders |
US8828068B2 (en) | 2007-07-17 | 2014-09-09 | Cardiac Pacemakers, Inc. | Systems and methods for local vasoactive response using temperature modulation |
US8702609B2 (en) | 2007-07-27 | 2014-04-22 | Meridian Cardiovascular Systems, Inc. | Image-guided intravascular therapy catheters |
US8821477B2 (en) | 2007-08-06 | 2014-09-02 | Boston Scientific Scimed, Inc. | Alternative micromachined structures |
US8066731B2 (en) | 2007-08-20 | 2011-11-29 | Olympus Medical Systems Corp. | Treatment device |
KR101282285B1 (ko) | 2007-08-20 | 2013-07-10 | 삼성전자주식회사 | 이동 통신 시스템에서 위치 기반 서비스 제공 시스템 및방법 |
US7863897B2 (en) | 2007-09-07 | 2011-01-04 | The General Hospital Corporation | Method and apparatus for characterizing the temporal resolution of an imaging device |
US20090069671A1 (en) | 2007-09-10 | 2009-03-12 | General Electric Company | Electric Motor Tracking System and Method |
US7777486B2 (en) | 2007-09-13 | 2010-08-17 | The Board Of Trustees Of The Leland Stanford Junior University | Magnetic resonance imaging with bipolar multi-echo sequences |
WO2009036471A1 (en) | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Prostate cancer ablation |
US9283034B2 (en) | 2007-09-26 | 2016-03-15 | Retrovascular, Inc. | Recanalization system using radiofrequency energy |
JP5479672B2 (ja) | 2007-09-27 | 2014-04-23 | シスメックス株式会社 | 血液または尿の分析装置およびデータ処理装置 |
JP2010540198A (ja) | 2007-10-05 | 2010-12-24 | コアプタス メディカル コーポレイション | 経中隔心臓処置のためのシステムおよび方法 |
WO2009055286A1 (en) | 2007-10-24 | 2009-04-30 | Edwards Lifesciences Corporation | Percutaneous nitinol stent extraction device |
US20100284927A1 (en) | 2007-10-26 | 2010-11-11 | University Of Utah Research Foundation | Use of mri contrast agents for evaluating the treatment of tumors |
US20090112202A1 (en) | 2007-10-31 | 2009-04-30 | Boston Scientific Scimed, Inc. | Dispersive electrode with thermochromatic properties |
US20090118620A1 (en) | 2007-11-06 | 2009-05-07 | General Electric Company | System and method for tracking an ultrasound catheter |
WO2009065078A1 (en) | 2007-11-14 | 2009-05-22 | Pathway Medical Technologies, Inc. | Delivery and administration of compositions using interventional catheters |
US20090131798A1 (en) | 2007-11-19 | 2009-05-21 | Minar Christopher D | Method and apparatus for intravascular imaging and occlusion crossing |
US20090143640A1 (en) | 2007-11-26 | 2009-06-04 | Voyage Medical, Inc. | Combination imaging and treatment assemblies |
KR20100102626A (ko) | 2007-11-30 | 2010-09-24 | 노파르티스 아게 | 근 위축 및 관련 장애의 치료를 위한 단백질 티로신 포스파타제 억제제 및 인간 성장 호르몬의 조합물 |
US20090287120A1 (en) | 2007-12-18 | 2009-11-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Circulatory monitoring systems and methods |
US8021413B2 (en) | 2007-12-27 | 2011-09-20 | Cook Medical Technologies Llc | Low profile medical device |
JP5576292B2 (ja) | 2007-12-27 | 2014-08-20 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 液体冷却剤を冷凍アブレーションデバイスに制御可能に送達するためのシステム |
US8366615B2 (en) | 2009-01-05 | 2013-02-05 | Texas Heart Institute | Introducer sheath with electrodes |
US8273023B2 (en) | 2009-01-05 | 2012-09-25 | Texas Heart Institute | Introducer sheathe with electrodes |
GB2456301A (en) | 2008-01-08 | 2009-07-15 | Gmj Design Ltd | Surface Representation from a Point Cloud |
US8676322B2 (en) | 2008-01-30 | 2014-03-18 | Boston Scientific Neuromodulation Corporation | Methods and systems of treating pancreatitis pain |
WO2009099550A1 (en) | 2008-02-07 | 2009-08-13 | Cardiac Pacemakers, Inc. | Wireless tissue electrostimulation |
US8858609B2 (en) | 2008-02-07 | 2014-10-14 | Intuitive Surgical Operations, Inc. | Stent delivery under direct visualization |
WO2009105482A1 (en) | 2008-02-19 | 2009-08-27 | Boston Scientific Scimed, Inc. | Apparatus for uniformly distributing coolant within a cryo-ablation device |
US20110040324A1 (en) | 2008-03-17 | 2011-02-17 | Mccarthy Patrick M | Devices and methods for percutaneous access, hemostasis, and closure |
WO2009121009A2 (en) | 2008-03-27 | 2009-10-01 | The Regents Of The University Of California | Irreversible electroporation device for use in attenuating neointimal |
US20090247966A1 (en) | 2008-03-28 | 2009-10-01 | Gunn Euen T | Methods and products for applying structured compositions to a substrate |
US20090253974A1 (en) | 2008-04-08 | 2009-10-08 | Marc Mounir Rahme | Use of tools, mapping systems, catheters, electrodes or any devices targeting any autonomic nerve(s) structure(s) in the human heart for the diagnostic, treatment and/or prevention of the recurrence of cardiac arrhythmias. |
US20090264755A1 (en) | 2008-04-22 | 2009-10-22 | National Taiwan University | High-Intensity Ultrasonic Vessel Ablator Using Blood Flow Signal for Precise Positioning |
US7956613B2 (en) | 2008-05-02 | 2011-06-07 | The General Hospital Corporation | Method for imaging acoustically induced rotary saturation with a magnetic resonance imaging system |
ES2398052T5 (es) | 2008-05-09 | 2021-10-25 | Nuvaira Inc | Sistemas para tratar un árbol bronquial |
US9028445B2 (en) | 2008-05-12 | 2015-05-12 | Frank W. Ingle | Apparatus and method for chilling cryo-ablation coolant and resulting cryo-ablation system |
JP5345678B2 (ja) | 2008-05-15 | 2013-11-20 | ボストン サイエンティフィック サイムド,インコーポレイテッド | 組織をクライオジェニック・アブレーション処理し、クライオジェニック・アブレーション領域を調整する装置 |
US8128617B2 (en) | 2008-05-27 | 2012-03-06 | Boston Scientific Scimed, Inc. | Electrical mapping and cryo ablating with a balloon catheter |
US8187261B2 (en) | 2008-05-29 | 2012-05-29 | Boston Scientific Scimed, Inc. | Regulating internal pressure of a cryotherapy balloon catheter |
US20090318749A1 (en) | 2008-06-19 | 2009-12-24 | Craig Stolen | Method and apparatus for pacing and intermittent ischemia |
US20100049099A1 (en) | 2008-07-18 | 2010-02-25 | Vytronus, Inc. | Method and system for positioning an energy source |
US20100030061A1 (en) | 2008-07-31 | 2010-02-04 | Canfield Monte R | Navigation system for cardiac therapies using gating |
US9597145B2 (en) | 2008-08-20 | 2017-03-21 | Prostacare Pty Ltd | Non-thermal ablation system for treating tissue |
US20100049283A1 (en) | 2008-08-21 | 2010-02-25 | Bliss Holdings, Llc | Illumination-based medical device & methods of use thereof |
AU2009282740A1 (en) | 2008-08-21 | 2010-02-25 | Med-El Elektromedizinische Geraete Gmbh | Multipath stimulation hearing systems |
US20100069837A1 (en) | 2008-09-16 | 2010-03-18 | Boston Scientific Scimed, Inc. | Balloon Assembly and Method for Therapeutic Agent Delivery |
CA2737785A1 (en) | 2008-09-22 | 2010-03-25 | Minnow Medical, Inc. | Inducing desirable temperature effects on body tissue using alternate energy sources |
DE102008048616B4 (de) | 2008-09-23 | 2010-08-05 | Olympus Winter & Ibe Gmbh | Urologischer Ballonkatheter |
DE102008050347B4 (de) | 2008-10-02 | 2011-01-20 | Siemens Aktiengesellschaft | Verfahren, Magnetresonanzanlage und Datenträger zur Bestimmung eines Nierenfunktionsparameters |
EP2349440B1 (en) | 2008-10-07 | 2019-08-21 | Mc10, Inc. | Catheter balloon having stretchable integrated circuitry and sensor array |
US8382753B2 (en) | 2008-10-21 | 2013-02-26 | Hermes Innovations, LLC | Tissue ablation methods |
US8923773B1 (en) * | 2008-10-29 | 2014-12-30 | University Of South Florida | Minimally invasive networked surgical system and method |
US8358981B1 (en) * | 2008-10-29 | 2013-01-22 | University Of South Florida | Minimally invasive networked surgical system and method |
US20100114244A1 (en) | 2008-10-31 | 2010-05-06 | Medtronic, Inc. | Electrical renal autonomic blockade |
ES2615826T3 (es) | 2008-11-11 | 2017-06-08 | Shifamed Holdings, Llc | Conjunto de electrodos de perfil bajo |
US8400164B2 (en) * | 2008-11-12 | 2013-03-19 | Biosense Webster, Inc. | Calibration and compensation for errors in position measurement |
US9468364B2 (en) | 2008-11-14 | 2016-10-18 | Intuitive Surgical Operations, Inc. | Intravascular catheter with hood and image processing systems |
CA2743992A1 (en) | 2008-11-17 | 2010-05-20 | Minnow Medical, Inc. | Selective accumulation of energy with or without knowledge of tissue topography |
EP2376189B1 (en) | 2008-12-09 | 2018-02-07 | Nephera Ltd. | Stimulation of the urinary system |
WO2010082993A2 (en) | 2008-12-11 | 2010-07-22 | Mc10, Inc. | Systems, methods, and devices using stretchable or flexible electronics for medical applications |
US20100160903A1 (en) | 2008-12-22 | 2010-06-24 | Yosef Krespi | Process and system for treating a vascular occlusion or other endoluminal structure |
US20100160906A1 (en) | 2008-12-23 | 2010-06-24 | Asthmatx, Inc. | Expandable energy delivery devices having flexible conductive elements and associated systems and methods |
US8317810B2 (en) | 2008-12-29 | 2012-11-27 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Tissue puncture assemblies and methods for puncturing tissue |
US9352174B2 (en) | 2008-12-30 | 2016-05-31 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation system with blood leakage minimization and tissue protective capabilities |
US8808345B2 (en) | 2008-12-31 | 2014-08-19 | Medtronic Ardian Luxembourg S.A.R.L. | Handle assemblies for intravascular treatment devices and associated systems and methods |
US8652129B2 (en) | 2008-12-31 | 2014-02-18 | Medtronic Ardian Luxembourg S.A.R.L. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
US20100168739A1 (en) | 2008-12-31 | 2010-07-01 | Ardian, Inc. | Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation |
EP2208506A1 (en) | 2009-01-16 | 2010-07-21 | Oncotherm Kft. | Intraluminar oncothermia catheter |
WO2010088301A1 (en) | 2009-01-27 | 2010-08-05 | Boveda Marco Medical Llc | Catheters and methods for performing electrophysiological interventions |
EP2404171A4 (en) | 2009-03-03 | 2016-01-27 | Mc10 Inc | SYSTEMS, METHODS AND DEVICES HAVING INTEGRATED INTEGRATED CIRCUIT ELEMENTS FOR DETECTING AND ADMINISTERING THERAPY |
US20100249604A1 (en) | 2009-03-31 | 2010-09-30 | Boston Scientific Corporation | Systems and methods for making and using a motor distally-positioned within a catheter of an intravascular ultrasound imaging system |
US8287532B2 (en) | 2009-04-13 | 2012-10-16 | Biosense Webster, Inc. | Epicardial mapping and ablation catheter |
ES2548253T3 (es) | 2009-04-20 | 2015-10-15 | Gilead Calistoga Llc | Métodos para el tratamiento de tumores sólidos |
WO2010124120A1 (en) | 2009-04-22 | 2010-10-28 | Mercator Medsystems, Inc. | Use of guanethidine for treating hypertension by local vascular delivery |
US8628524B2 (en) | 2009-04-27 | 2014-01-14 | Bovie Medical Corporation | Return electrode detection and monitoring system and method thereof |
US8517955B2 (en) | 2009-05-08 | 2013-08-27 | Broncus Medical Inc. | Tissue sampling devices, systems and methods |
US8551096B2 (en) | 2009-05-13 | 2013-10-08 | Boston Scientific Scimed, Inc. | Directional delivery of energy and bioactives |
US8292881B2 (en) | 2009-05-27 | 2012-10-23 | Vivant Medical, Inc. | Narrow gauge high strength choked wet tip microwave ablation antenna |
WO2011006017A1 (en) | 2009-07-08 | 2011-01-13 | Sanuwave, Inc. | Usage of extracorporeal and intracorporeal pressure shock waves in medicine |
WO2011005901A2 (en) | 2009-07-09 | 2011-01-13 | Silhouette Medical Inc. | Apparatus for treating medical conditions of hollow anatomical structures |
US20110071400A1 (en) | 2009-09-23 | 2011-03-24 | Boston Scientific Scimed, Inc. | Systems and methods for making and using intravascular ultrasound imaging systems with sealed imaging cores |
US20110071401A1 (en) | 2009-09-24 | 2011-03-24 | Boston Scientific Scimed, Inc. | Systems and methods for making and using a stepper motor for an intravascular ultrasound imaging system |
US8343145B2 (en) | 2009-09-28 | 2013-01-01 | Vivant Medical, Inc. | Microwave surface ablation using conical probe |
US9101733B2 (en) | 2009-09-29 | 2015-08-11 | Biosense Webster, Inc. | Catheter with biased planar deflection |
US8986302B2 (en) * | 2009-10-09 | 2015-03-24 | Ethicon Endo-Surgery, Inc. | Surgical generator for ultrasonic and electrosurgical devices |
US20110092880A1 (en) | 2009-10-12 | 2011-04-21 | Michael Gertner | Energetic modulation of nerves |
US20110118600A1 (en) | 2009-11-16 | 2011-05-19 | Michael Gertner | External Autonomic Modulation |
US8295912B2 (en) | 2009-10-12 | 2012-10-23 | Kona Medical, Inc. | Method and system to inhibit a function of a nerve traveling with an artery |
US9174065B2 (en) | 2009-10-12 | 2015-11-03 | Kona Medical, Inc. | Energetic modulation of nerves |
EP2995350B1 (en) | 2009-10-30 | 2016-08-03 | ReCor Medical, Inc. | Apparatus for treatment of hypertension through percutaneous ultrasound renal denervation |
AU2010313313A1 (en) | 2009-10-30 | 2012-06-07 | Sound Interventions, Inc. | Method and apparatus for non-invasive treatment of hypertension through ultrasound renal denervation |
US20110112400A1 (en) | 2009-11-06 | 2011-05-12 | Ardian, Inc. | High intensity focused ultrasound catheter apparatuses, systems, and methods for renal neuromodulation |
CA2781951A1 (en) | 2009-11-13 | 2011-05-19 | St. Jude Medical, Inc. | Assembly of staggered ablation elements |
US20110137155A1 (en) | 2009-12-09 | 2011-06-09 | Boston Scientific Scimed, Inc. | Delivery device for localized delivery of a therapeutic agent |
US9179827B2 (en) | 2009-12-15 | 2015-11-10 | Boston Scientific Scimed, Inc. | Systems and methods for determining the position and orientation of medical devices inserted into a patient |
US20110270238A1 (en) | 2009-12-31 | 2011-11-03 | Raed Rizq | Compliant Cryoballoon Apparatus for Denervating Ostia of the Renal Arteries |
US20110263921A1 (en) | 2009-12-31 | 2011-10-27 | Anthony Vrba | Patterned Denervation Therapy for Innervated Renal Vasculature |
US20110264116A1 (en) | 2009-12-31 | 2011-10-27 | Gordon Kocur | Compressive Denervation Apparatus for Innervated Renal Vasculature |
US20110200171A1 (en) | 2010-01-19 | 2011-08-18 | Ardian, Inc. | Methods and apparatus for renal neuromodulation via stereotactic radiotherapy |
DE102010000396A1 (de) * | 2010-02-12 | 2011-08-18 | Erbe Elektromedizin GmbH, 72072 | HF-Chirurgiegerät |
CA2793737A1 (en) | 2010-03-24 | 2011-09-29 | Shifamed Holdings, Llc | Intravascular tissue disruption |
CA2795229A1 (en) | 2010-04-09 | 2011-10-13 | Vessix Vascular, Inc. | Power generating and control apparatus for the treatment of tissue |
US20110257641A1 (en) | 2010-04-14 | 2011-10-20 | Roger Hastings | Phototherapy for renal denervation |
CA2795933A1 (en) | 2010-04-14 | 2011-10-20 | Boston Scientific Scimed, Inc. | Renal artery denervation apparatus employing helical shaping arrangement |
US9192790B2 (en) | 2010-04-14 | 2015-11-24 | Boston Scientific Scimed, Inc. | Focused ultrasonic renal denervation |
US20110257642A1 (en) | 2010-04-16 | 2011-10-20 | Griggs Iii Charles Sherman | Method for producing a permanent or nearly permanent skin image, design or tattoo by freezing the skin |
US8870863B2 (en) | 2010-04-26 | 2014-10-28 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses, systems, and methods for renal neuromodulation |
US8845631B2 (en) * | 2010-04-28 | 2014-09-30 | Medtronic Ablation Frontiers Llc | Systems and methods of performing medical procedures |
US9724509B2 (en) * | 2010-06-07 | 2017-08-08 | Medtronic, Inc. | Selective termination of stimulation to deliver post-stimulation therapeutic effect |
US8473067B2 (en) | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
US8120518B2 (en) | 2010-06-14 | 2012-02-21 | Koren Advanced Institute of Science and Technology | Digital feedforward sigma-delta modulator in analog-to-digital converter and modulation method thereof |
US9358020B2 (en) | 2010-06-25 | 2016-06-07 | Boston Scientific Scimed Inc. | Catheter device for delivery energy to a vein |
US20120029496A1 (en) | 2010-07-30 | 2012-02-02 | Scott Smith | Renal nerve ablation using mild freezing and microwave energy |
US9084609B2 (en) | 2010-07-30 | 2015-07-21 | Boston Scientific Scime, Inc. | Spiral balloon catheter for renal nerve ablation |
US9155589B2 (en) | 2010-07-30 | 2015-10-13 | Boston Scientific Scimed, Inc. | Sequential activation RF electrode set for renal nerve ablation |
US9463062B2 (en) | 2010-07-30 | 2016-10-11 | Boston Scientific Scimed, Inc. | Cooled conductive balloon RF catheter for renal nerve ablation |
US9358365B2 (en) | 2010-07-30 | 2016-06-07 | Boston Scientific Scimed, Inc. | Precision electrode movement control for renal nerve ablation |
US9408661B2 (en) | 2010-07-30 | 2016-08-09 | Patrick A. Haverkost | RF electrodes on multiple flexible wires for renal nerve ablation |
US20120029512A1 (en) | 2010-07-30 | 2012-02-02 | Willard Martin R | Balloon with surface electrodes and integral cooling for renal nerve ablation |
US20120029505A1 (en) | 2010-07-30 | 2012-02-02 | Jenson Mark L | Self-Leveling Electrode Sets for Renal Nerve Ablation |
EP3998030A1 (en) | 2010-08-05 | 2022-05-18 | Medtronic Ireland Manufacturing Unlimited Company | Cryoablation apparatuses, systems, and methods for renal neuromodulation |
WO2012033860A1 (en) | 2010-09-07 | 2012-03-15 | Boston Scientific Scimed, Inc. | Self-powered ablation catheter for renal denervation |
US20120059241A1 (en) | 2010-09-08 | 2012-03-08 | Boston Scientific Scimed, Inc. | Systems and methods for making and using a steerable imaging system configured and arranged for insertion into a patient |
US20120065554A1 (en) | 2010-09-09 | 2012-03-15 | Michael Pikus | Dual Balloon Ablation Catheter with Vessel Deformation Arrangement for Renal Nerve Ablation |
US20120065506A1 (en) | 2010-09-10 | 2012-03-15 | Scott Smith | Mechanical, Electromechanical, and/or Elastographic Assessment for Renal Nerve Ablation |
JP2013544565A (ja) | 2010-10-20 | 2013-12-19 | メドトロニック アーディアン ルクセンブルク ソシエテ ア レスポンサビリテ リミテ | 腎神経調節のための拡張可能なメッシュ構造を有するカテーテル器具並びに関連するシステムおよび方法 |
TWI556849B (zh) | 2010-10-21 | 2016-11-11 | 美敦力阿福盧森堡公司 | 用於腎臟神經協調的導管裝置 |
BR112013010007A2 (pt) | 2010-10-25 | 2017-10-24 | Medtronic Ardian Luxembourg | aparelho de cateter |
EP3449856B1 (en) | 2010-10-25 | 2023-06-28 | Medtronic Ardian Luxembourg S.à.r.l. | Device for evaluation and feedback of neuromodulation treatment |
EP4059459A1 (en) | 2010-10-25 | 2022-09-21 | Medtronic Ireland Manufacturing Unlimited Company | Microwave catheter apparatuses for renal neuromodulation |
US8974451B2 (en) | 2010-10-25 | 2015-03-10 | Boston Scientific Scimed, Inc. | Renal nerve ablation using conductive fluid jet and RF energy |
US9060754B2 (en) | 2010-10-26 | 2015-06-23 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
US20120130458A1 (en) | 2010-10-26 | 2012-05-24 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation cryotherapeutic devices and associated systems and methods |
US20120109021A1 (en) | 2010-10-27 | 2012-05-03 | Roger Hastings | Renal denervation catheter employing acoustic wave generator arrangement |
US9220558B2 (en) | 2010-10-27 | 2015-12-29 | Boston Scientific Scimed, Inc. | RF renal denervation catheter with multiple independent electrodes |
US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
US9089350B2 (en) | 2010-11-16 | 2015-07-28 | Boston Scientific Scimed, Inc. | Renal denervation catheter with RF electrode and integral contrast dye injection arrangement |
US9668811B2 (en) | 2010-11-16 | 2017-06-06 | Boston Scientific Scimed, Inc. | Minimally invasive access for renal nerve ablation |
US20120123261A1 (en) | 2010-11-16 | 2012-05-17 | Jenson Mark L | Renal Nerve Ablation Using Mild Freezing and Vibration |
US9326751B2 (en) | 2010-11-17 | 2016-05-03 | Boston Scientific Scimed, Inc. | Catheter guidance of external energy for renal denervation |
US9060761B2 (en) | 2010-11-18 | 2015-06-23 | Boston Scientific Scime, Inc. | Catheter-focused magnetic field induced renal nerve ablation |
EP2640297B1 (en) | 2010-11-19 | 2016-03-30 | Boston Scientific Scimed, Inc. | Renal nerve detection and ablation apparatus |
US9192435B2 (en) | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
US9023034B2 (en) | 2010-11-22 | 2015-05-05 | Boston Scientific Scimed, Inc. | Renal ablation electrode with force-activatable conduction apparatus |
US20120136349A1 (en) | 2010-11-30 | 2012-05-31 | Roger Hastings | RENAL DENERVATION CATHETER AND METHOD USING pH ALTERATION |
US20120157992A1 (en) | 2010-12-15 | 2012-06-21 | Scott Smith | Off-wall electrode device for renal nerve ablation |
US20120157993A1 (en) | 2010-12-15 | 2012-06-21 | Jenson Mark L | Bipolar Off-Wall Electrode Device for Renal Nerve Ablation |
US20120232409A1 (en) | 2010-12-15 | 2012-09-13 | Stahmann Jeffrey E | System and method for renal artery occlusion during renal denervation therapy |
US20120184952A1 (en) | 2011-01-19 | 2012-07-19 | Jenson Mark L | Low-profile off-wall electrode device for renal nerve ablation |
US9220561B2 (en) | 2011-01-19 | 2015-12-29 | Boston Scientific Scimed, Inc. | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury |
EP2734259B1 (en) | 2011-07-20 | 2016-11-23 | Boston Scientific Scimed, Inc. | Percutaneous device to visualize, target and ablate nerves |
CN103813829B (zh) | 2011-07-22 | 2016-05-18 | 波士顿科学西美德公司 | 具有可定位于螺旋引导件中的神经调制元件的神经调制系统 |
US20130035681A1 (en) | 2011-08-04 | 2013-02-07 | Boston Scientific Scimed, Inc. | Novel catheter for contiguous rf ablation |
US8702619B2 (en) | 2011-08-26 | 2014-04-22 | Symap Holding Limited | Mapping sympathetic nerve distribution for renal ablation and catheters for same |
US9427579B2 (en) | 2011-09-29 | 2016-08-30 | Pacesetter, Inc. | System and method for performing renal denervation verification |
CN103826694B (zh) | 2011-09-30 | 2017-03-22 | 柯惠有限合伙公司 | 能量传递装置以及使用方法 |
US20130090578A1 (en) | 2011-10-10 | 2013-04-11 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation |
US9186210B2 (en) | 2011-10-10 | 2015-11-17 | Boston Scientific Scimed, Inc. | Medical devices including ablation electrodes |
CN103857353B (zh) | 2011-10-11 | 2017-03-01 | 波士顿科学西美德公司 | 具有绝缘尖端的消融导管 |
US9420955B2 (en) | 2011-10-11 | 2016-08-23 | Boston Scientific Scimed, Inc. | Intravascular temperature monitoring system and method |
US20130090649A1 (en) | 2011-10-11 | 2013-04-11 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation |
US20130090650A1 (en) | 2011-10-11 | 2013-04-11 | Boston Scientific Scimed, Inc. | Renal nerve ablation cooling device and technique |
EP2765940B1 (en) | 2011-10-11 | 2015-08-26 | Boston Scientific Scimed, Inc. | Off-wall electrode device for nerve modulation |
US9364284B2 (en) | 2011-10-12 | 2016-06-14 | Boston Scientific Scimed, Inc. | Method of making an off-wall spacer cage |
EP2768563B1 (en) | 2011-10-18 | 2016-11-09 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
US20130096550A1 (en) | 2011-10-18 | 2013-04-18 | Boston Scientific Scimed, Inc. | Ablative catheter with electrode cooling and related methods of use |
US9079000B2 (en) | 2011-10-18 | 2015-07-14 | Boston Scientific Scimed, Inc. | Integrated crossing balloon catheter |
US20130110106A1 (en) | 2011-10-28 | 2013-05-02 | Boston Scientific Scimed, Inc. | Expandable structure for off-wall ablation electrode |
EP2775948B1 (en) | 2011-11-08 | 2018-04-04 | Boston Scientific Scimed, Inc. | Ostial renal nerve ablation |
US9265969B2 (en) | 2011-12-21 | 2016-02-23 | Cardiac Pacemakers, Inc. | Methods for modulating cell function |
CA2861622C (en) | 2011-12-23 | 2020-10-27 | Vessix Vascular, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
US20130172877A1 (en) | 2011-12-28 | 2013-07-04 | Boston Scientific Scimed, Inc. | Balloon expandable multi-electrode rf ablation catheter |
CN104135958B (zh) | 2011-12-28 | 2017-05-03 | 波士顿科学西美德公司 | 用有聚合物消融元件的新消融导管调变神经的装置和方法 |
US20130172880A1 (en) | 2011-12-29 | 2013-07-04 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices and methods for renal nerve modulation |
WO2013101485A1 (en) | 2011-12-29 | 2013-07-04 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation monitoring |
US20130172879A1 (en) | 2011-12-29 | 2013-07-04 | Boston Scientific Scimed, Inc. | Renal nerve modulation medical devices |
US9050106B2 (en) | 2011-12-29 | 2015-06-09 | Boston Scientific Scimed, Inc. | Off-wall electrode device and methods for nerve modulation |
US9095350B2 (en) * | 2012-05-01 | 2015-08-04 | Medtronic Ablation Frontiers Llc | Impedance detection of venous placement of multi-electrode catheters |
CN104768487A (zh) | 2012-09-13 | 2015-07-08 | 波士顿科学西美德公司 | 肾脏神经调节球囊及其制造和使用方法 |
EP2967725B1 (en) * | 2013-03-15 | 2019-12-11 | Boston Scientific Scimed, Inc. | Control unit for detecting electrical leakage between electrode pads and system comprising such a control unit |
-
2014
- 2014-03-04 EP EP14710770.0A patent/EP2967725B1/en active Active
- 2014-03-04 CN CN201480028576.7A patent/CN105228546B/zh not_active Expired - Fee Related
- 2014-03-04 US US14/196,829 patent/US9297845B2/en active Active
- 2014-03-04 AU AU2014237950A patent/AU2014237950B2/en not_active Ceased
- 2014-03-04 JP JP2016500610A patent/JP6139772B2/ja not_active Expired - Fee Related
- 2014-03-04 WO PCT/US2014/020368 patent/WO2014149690A2/en active Application Filing
-
2016
- 2016-02-16 US US15/045,108 patent/US10371734B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009518151A (ja) * | 2005-12-06 | 2009-05-07 | セント・ジュード・メディカル・エイトリアル・フィブリレーション・ディヴィジョン・インコーポレーテッド | 組織切除のための電極結合の評価 |
JP2010507404A (ja) * | 2006-10-18 | 2010-03-11 | ミノウ・メディカル・インコーポレーテッド | 身体組織に望ましい温度作用を誘発するシステム |
JP2010507403A (ja) * | 2006-10-18 | 2010-03-11 | ミノウ・メディカル・インコーポレーテッド | 標的組織の選択的な処置のための調節されたrfエネルギーおよび電気的な組織の特徴付け |
JP2010526557A (ja) * | 2007-02-06 | 2010-08-05 | アラゴン サージカル インク | 電気焼灼方法と装置 |
Also Published As
Publication number | Publication date |
---|---|
US20140266235A1 (en) | 2014-09-18 |
EP2967725A2 (en) | 2016-01-20 |
EP2967725B1 (en) | 2019-12-11 |
WO2014149690A3 (en) | 2015-01-08 |
US10371734B2 (en) | 2019-08-06 |
US9297845B2 (en) | 2016-03-29 |
JP6139772B2 (ja) | 2017-05-31 |
WO2014149690A2 (en) | 2014-09-25 |
CN105228546B (zh) | 2017-11-14 |
AU2014237950A1 (en) | 2015-10-08 |
AU2014237950B2 (en) | 2017-04-13 |
CN105228546A (zh) | 2016-01-06 |
US20160161540A1 (en) | 2016-06-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6139772B2 (ja) | 電極パッドと共に使用するための制御ユニットおよび漏電を推定するための方法 | |
JP6220044B2 (ja) | 腎神経アブレーションのための医療用デバイス | |
JP6568138B2 (ja) | 身体通路の組織又は身体通路に隣接する組織をリモデリングするためのデバイス |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20160914 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160920 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20161219 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20170220 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20170404 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20170427 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6139772 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
LAPS | Cancellation because of no payment of annual fees |