|
FR7461M
(enExample)
|
1968-06-19 |
1970-01-05 |
|
|
|
GB1355961A
(en)
|
1970-02-27 |
1974-06-12 |
Wellcome Found |
Preparation of immunosuppressive antilymphocytic serum
|
|
CH594444A5
(enExample)
*
|
1972-12-04 |
1978-01-13 |
Gerd Birrenbach |
|
|
DK143689C
(da)
|
1975-03-20 |
1982-03-15 |
J Kreuter |
Fremgangsmaade til fremstilling af en adsorberet vaccine
|
|
US4756907A
(en)
|
1978-10-17 |
1988-07-12 |
Stolle Research & Development Corp. |
Active/passive immunization of the internal female reproductive organs
|
|
US4946929A
(en)
|
1983-03-22 |
1990-08-07 |
Massachusetts Institute Of Technology |
Bioerodible articles useful as implants and prostheses having predictable degradation rates
|
|
US6309669B1
(en)
|
1984-03-16 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
|
|
US4638045A
(en)
|
1985-02-19 |
1987-01-20 |
Massachusetts Institute Of Technology |
Non-peptide polyamino acid bioerodible polymers
|
|
US4631211A
(en)
|
1985-03-25 |
1986-12-23 |
Scripps Clinic & Research Foundation |
Means for sequential solid phase organic synthesis and methods using the same
|
|
US4806621A
(en)
|
1986-01-21 |
1989-02-21 |
Massachusetts Institute Of Technology |
Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
|
|
JPS63122620A
(ja)
|
1986-11-12 |
1988-05-26 |
Sanraku Inc |
ポリ乳酸マイクロスフエア及びその製造方法
|
|
US5736372A
(en)
|
1986-11-20 |
1998-04-07 |
Massachusetts Institute Of Technology |
Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
|
|
CA1340581C
(en)
|
1986-11-20 |
1999-06-08 |
Joseph P. Vacanti |
Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
|
|
US5759830A
(en)
|
1986-11-20 |
1998-06-02 |
Massachusetts Institute Of Technology |
Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
|
|
FR2608988B1
(fr)
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
|
|
US5912017A
(en)
|
1987-05-01 |
1999-06-15 |
Massachusetts Institute Of Technology |
Multiwall polymeric microspheres
|
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
|
US5019379A
(en)
|
1987-07-31 |
1991-05-28 |
Massachusetts Institute Of Technology |
Unsaturated polyanhydrides
|
|
US6130082A
(en)
|
1988-05-05 |
2000-10-10 |
American Cyanamid Company |
Recombinant flagellin vaccines
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5010167A
(en)
|
1989-03-31 |
1991-04-23 |
Massachusetts Institute Of Technology |
Poly(amide-and imide-co-anhydride) for biological application
|
|
US5114703A
(en)
|
1989-05-30 |
1992-05-19 |
Alliance Pharmaceutical Corp. |
Percutaneous lymphography using particulate fluorocarbon emulsions
|
|
US5733572A
(en)
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
GB9016885D0
(en)
*
|
1990-08-01 |
1990-09-12 |
Scras |
Sustained release pharmaceutical compositions
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
DK0531497T3
(da)
|
1991-04-02 |
1998-03-23 |
Biotech Australia Pty Ltd |
Orale indgivelsessystemer til mikropartikler
|
|
US5811447A
(en)
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
|
US6235313B1
(en)
|
1992-04-24 |
2001-05-22 |
Brown University Research Foundation |
Bioadhesive microspheres and their use as drug delivery and imaging systems
|
|
EP0654973A4
(en)
|
1992-07-21 |
1995-08-09 |
Gen Hospital Corp |
ARRANGEMENT FOR DELIVERING MEDICINES TO THE LYMPHIC TISSUE.
|
|
GB9216082D0
(en)
|
1992-07-28 |
1992-09-09 |
Univ Nottingham |
Lymphatic delivery composition
|
|
US6608201B2
(en)
|
1992-08-28 |
2003-08-19 |
3M Innovative Properties Company |
Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2695563B1
(fr)
|
1992-09-11 |
1994-12-02 |
Pasteur Institut |
Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
|
|
AU4932493A
(en)
|
1992-09-25 |
1994-04-26 |
Dynagen, Inc. |
An immunobooster for delayed release of immunogen
|
|
US5399665A
(en)
|
1992-11-05 |
1995-03-21 |
Massachusetts Institute Of Technology |
Biodegradable polymers for cell transplantation
|
|
DE69418699T2
(de)
|
1993-01-11 |
1999-09-30 |
Dana-Farber Cancer Institute, Boston |
Induktion der antworten zytotoxischer t-lymphozyten
|
|
US5512600A
(en)
|
1993-01-15 |
1996-04-30 |
Massachusetts Institute Of Technology |
Preparation of bonded fiber structures for cell implantation
|
|
US5514378A
(en)
|
1993-02-01 |
1996-05-07 |
Massachusetts Institute Of Technology |
Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
|
|
JPH08507070A
(ja)
|
1993-02-22 |
1996-07-30 |
アルザ・コーポレーション |
活性物質の経口投与のための組成物
|
|
JPH08508721A
(ja)
|
1993-03-17 |
1996-09-17 |
シリカゲル ゲス．エム．ビー．エイチ |
超常磁性粒子、その製法及びその用途
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
WO1995003035A1
(en)
|
1993-07-23 |
1995-02-02 |
Massachusetts Institute Of Technology |
Polymerized liposomes with enhanced stability for oral delivery
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US5798340A
(en)
|
1993-09-17 |
1998-08-25 |
Gilead Sciences, Inc. |
Nucleotide analogs
|
|
US5500161A
(en)
*
|
1993-09-21 |
1996-03-19 |
Massachusetts Institute Of Technology And Virus Research Institute |
Method for making hydrophobic polymeric microparticles
|
|
JP2930421B2
(ja)
|
1994-02-28 |
1999-08-03 |
メディノヴァ メディカル コンサルティング ゲゼルシャフト ミット ベシュレンクテル ハフツング |
薬剤組成物、その製造方法及びその使用方法
|
|
GB9412273D0
(en)
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
AU713040B2
(en)
|
1994-07-15 |
1999-11-18 |
University Of Iowa Research Foundation, The |
Immunomodulatory oligonucleotides
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6007845A
(en)
|
1994-07-22 |
1999-12-28 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US5716404A
(en)
|
1994-12-16 |
1998-02-10 |
Massachusetts Institute Of Technology |
Breast tissue engineering
|
|
ATE252894T1
(de)
|
1995-01-05 |
2003-11-15 |
Univ Michigan |
Oberflächen-modifizierte nanopartikel und verfahren für ihre herstellung und verwendung
|
|
US6123727A
(en)
|
1995-05-01 |
2000-09-26 |
Massachusetts Institute Of Technology |
Tissue engineered tendons and ligaments
|
|
WO1997004747A1
(en)
|
1995-07-27 |
1997-02-13 |
Dunn James M |
Drug delivery systems for macromolecular drugs
|
|
AU710347B2
(en)
|
1995-08-31 |
1999-09-16 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of an agent
|
|
US6095148A
(en)
|
1995-11-03 |
2000-08-01 |
Children's Medical Center Corporation |
Neuronal stimulation using electrically conducting polymers
|
|
US5902599A
(en)
|
1996-02-20 |
1999-05-11 |
Massachusetts Institute Of Technology |
Biodegradable polymer networks for use in orthopedic and dental applications
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US5922695A
(en)
|
1996-07-26 |
1999-07-13 |
Gilead Sciences, Inc. |
Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
|
|
US6368598B1
(en)
|
1996-09-16 |
2002-04-09 |
Jcrt Radiation Oncology Support Services, Inc. |
Drug complex for treatment of metastatic prostate cancer
|
|
JP4391592B2
(ja)
|
1996-10-25 |
2009-12-24 |
スリーエム カンパニー |
Ｔｈ２介在性および関連疾患治療のための免疫応答修飾化合物
|
|
US6042820A
(en)
|
1996-12-20 |
2000-03-28 |
Connaught Laboratories Limited |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
|
|
WO2000006123A1
(en)
|
1998-07-29 |
2000-02-10 |
Chiron Corporation |
Microparticles with adsorbent surfaces, methods of making same, and uses thereof
|
|
CA2281838A1
(en)
|
1997-02-28 |
1998-09-03 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated cpg dinucleotide in the treatment of lps-associated disorders
|
|
AU753688B2
(en)
|
1997-03-10 |
2002-10-24 |
Ottawa Civic Loeb Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6211159B1
(en)
|
1997-04-11 |
2001-04-03 |
University Of Toronto |
Flagellin gene, FlaC of campylobacter
|
|
US6060082A
(en)
*
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
EP1003531B1
(en)
|
1997-05-20 |
2007-08-22 |
Ottawa Health Research Institute |
Processes for preparing nucleic acid constructs
|
|
US5837752A
(en)
|
1997-07-17 |
1998-11-17 |
Massachusetts Institute Of Technology |
Semi-interpenetrating polymer networks
|
|
US6989435B2
(en)
*
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
DE19745950A1
(de)
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
JP4375901B2
(ja)
*
|
1997-11-28 |
2009-12-02 |
大日本住友製薬株式会社 |
新規な複素環化合物
|
|
US6197229B1
(en)
|
1997-12-12 |
2001-03-06 |
Massachusetts Institute Of Technology |
Method for high supercoiled DNA content microspheres
|
|
US6254890B1
(en)
|
1997-12-12 |
2001-07-03 |
Massachusetts Institute Of Technology |
Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
|
|
FR2775435B1
(fr)
|
1998-02-27 |
2000-05-26 |
Bioalliance Pharma |
Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
|
|
US6232287B1
(en)
*
|
1998-03-13 |
2001-05-15 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
US6686446B2
(en)
|
1998-03-19 |
2004-02-03 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
US6506577B1
(en)
|
1998-03-19 |
2003-01-14 |
The Regents Of The University Of California |
Synthesis and crosslinking of catechol containing copolypeptides
|
|
US6632922B1
(en)
|
1998-03-19 |
2003-10-14 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
US6218371B1
(en)
|
1998-04-03 |
2001-04-17 |
University Of Iowa Research Foundation |
Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
|
|
EP1077708A1
(en)
|
1998-05-06 |
2001-02-28 |
University Of Iowa Research Foundation |
Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
|
|
DE19827164A1
(de)
*
|
1998-06-18 |
1999-12-23 |
Merck Patent Gmbh |
Katalytisch Titan(IV)-oxid vermittelte geminale symmetrische Dialkylierung von Carbonsäureamiden
|
|
US6242589B1
(en)
|
1998-07-14 |
2001-06-05 |
Isis Pharmaceuticals, Inc. |
Phosphorothioate oligonucleotides having modified internucleoside linkages
|
|
DE19839214C1
(de)
*
|
1998-08-28 |
2000-05-25 |
Aventis Res & Tech Gmbh & Co |
Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
|
|
US6306640B1
(en)
|
1998-10-05 |
2001-10-23 |
Genzyme Corporation |
Melanoma antigenic peptides
|
|
IL142896A0
(en)
*
|
1998-11-02 |
2002-04-21 |
Elan Corp Plc |
Multiparticulate modified release composition
|
|
US7521068B2
(en)
|
1998-11-12 |
2009-04-21 |
Elan Pharma International Ltd. |
Dry powder aerosols of nanoparticulate drugs
|
|
US7238711B1
(en)
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US6444192B1
(en)
|
1999-02-05 |
2002-09-03 |
The Regents Of The University Of California |
Diagnostic imaging of lymph structures
|
|
US7390780B2
(en)
|
1999-04-23 |
2008-06-24 |
Alza Corporation |
Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification
|
|
HUP0201425A3
(en)
|
1999-04-23 |
2006-07-28 |
Hadasit Med Res Service |
Conjugate having a cleavable linkage for use in a liposome
|
|
US7238368B2
(en)
|
1999-04-23 |
2007-07-03 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
US6800296B1
(en)
|
1999-05-19 |
2004-10-05 |
Massachusetts Institute Of Technology |
Modification of surfaces using biological recognition events
|
|
US6815170B1
(en)
|
1999-06-30 |
2004-11-09 |
John Wayne Cancer Institute |
Methods for lymph node identification
|
|
EP1202671A4
(en)
|
1999-08-13 |
2004-11-10 |
Point Biomedical Corp |
MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
|
|
CA2391534A1
(en)
|
1999-11-15 |
2001-05-25 |
Drug Innovation & Design, Inc. |
Selective cellular targeting: multifunctional delivery vehicles
|
|
CA2396113C
(en)
|
2000-01-13 |
2009-04-07 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
US20050020525A1
(en)
*
|
2002-02-20 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20050032733A1
(en)
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
|
MXPA02008361A
(es)
|
2000-02-28 |
2004-05-17 |
Genesegues Inc |
Sistema y metodo de encapsulacion de nanocapsulas.
|
|
US7129222B2
(en)
*
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
US7192725B2
(en)
|
2000-05-19 |
2007-03-20 |
University Of Toronto |
Flagellin gene, flaC of Campylobacter
|
|
WO2002100325A2
(en)
|
2000-10-13 |
2002-12-19 |
Ligocyte Pharmaceuticals, Inc. |
Polyvalent nanoparticles
|
|
GB0025414D0
(en)
|
2000-10-16 |
2000-11-29 |
Consejo Superior Investigacion |
Nanoparticles
|
|
CA2426692C
(en)
|
2000-10-19 |
2011-01-25 |
Eidgenossische Technische Hochschule Zurich |
Block copolymers for multifunctional self-assembled systems
|
|
US7592008B2
(en)
|
2000-11-20 |
2009-09-22 |
The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois |
Membrane scaffold proteins
|
|
US7097837B2
(en)
|
2001-02-19 |
2006-08-29 |
Pharmexa A/S |
Synthetic vaccine agents
|
|
US20030175950A1
(en)
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
|
EP2545937A1
(en)
|
2001-06-05 |
2013-01-16 |
The Regents Of The University Of Michigan |
Nanoemulsion vaccines
|
|
JP2005514326A
(ja)
|
2001-07-10 |
2005-05-19 |
コリクサ コーポレイション |
ミクロスフェア中に封入されたタンパク質およびアジュバントを送達するための組成物および方法
|
|
AU2002326561B2
(en)
|
2001-08-07 |
2008-04-03 |
Dynavax Technologies Corporation |
Immunomodulatory compositions, formulations, and methods for use thereof
|
|
WO2003020797A1
(en)
|
2001-08-30 |
2003-03-13 |
The Regents Of The University Of California |
Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers
|
|
US8088388B2
(en)
|
2002-02-14 |
2012-01-03 |
United Biomedical, Inc. |
Stabilized synthetic immunogen delivery system
|
|
JP4646516B2
(ja)
*
|
2002-02-20 |
2011-03-09 |
ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド |
吸着したポリペプチド含有分子を有する微粒子
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
US7635463B2
(en)
*
|
2002-02-27 |
2009-12-22 |
Pharmain Corporation |
Compositions for delivery of therapeutics and other materials
|
|
NZ535952A
(en)
|
2002-04-04 |
2009-01-31 |
Coley Pharm Gmbh |
Immunostimulatory G,U-containing oligoribonucleotides
|
|
US20040038303A1
(en)
*
|
2002-04-08 |
2004-02-26 |
Unger Gretchen M. |
Biologic modulations with nanoparticles
|
|
US7285289B2
(en)
*
|
2002-04-12 |
2007-10-23 |
Nagy Jon O |
Nanoparticle vaccines
|
|
US20080233181A1
(en)
|
2002-04-12 |
2008-09-25 |
Nagy Jon O |
Nanoparticle adjuvants for sub-unit vaccines
|
|
EP1499895B1
(en)
|
2002-04-22 |
2008-05-07 |
University Of Florida |
Functionalized nanoparticles and methods of use
|
|
US7375234B2
(en)
*
|
2002-05-30 |
2008-05-20 |
The Scripps Research Institute |
Copper-catalysed ligation of azides and acetylenes
|
|
AU2003276131A1
(en)
|
2002-06-18 |
2003-12-31 |
Epigenesis Pharmaceuticals, Inc. |
A dry powder oligonucleotide formulation, preparation and its uses
|
|
AU2003269904A1
(en)
|
2002-07-10 |
2004-01-23 |
The Ohio State University Research Foundation |
Antigen-polymer compositions
|
|
NZ537003A
(en)
*
|
2002-07-18 |
2008-03-28 |
Cytos Biotechnology Ag |
Hapten-carrier conjugates comprising virus like particles and uses thereof
|
|
US7488792B2
(en)
|
2002-08-28 |
2009-02-10 |
Burnham Institute For Medical Research |
Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
|
|
AU2003302226A1
(en)
|
2002-09-24 |
2004-06-30 |
University Of Kentucky Research Foundation |
Nanoparticle-based vaccine delivery system containing adjuvant
|
|
US7008411B1
(en)
*
|
2002-09-30 |
2006-03-07 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for treating vulnerable plaque
|
|
NO20024755D0
(no)
|
2002-10-03 |
2002-10-03 |
Amersham Health As |
Metode
|
|
SE0203687D0
(sv)
*
|
2002-12-13 |
2002-12-13 |
Ian Harwigsson Med Adagit Fa |
Pharmaceutical Porous Particles
|
|
US20040156846A1
(en)
|
2003-02-06 |
2004-08-12 |
Triton Biosystems, Inc. |
Therapy via targeted delivery of nanoscale particles using L6 antibodies
|
|
US8575110B2
(en)
*
|
2003-02-17 |
2013-11-05 |
Alpha-O Peptides G |
Peptidic nanoparticles as drug delivery and antigen display systems
|
|
US20040191215A1
(en)
|
2003-03-25 |
2004-09-30 |
Michael Froix |
Compositions for induction of a therapeutic response
|
|
CN101675993A
(zh)
|
2003-03-26 |
2010-03-24 |
赛托斯生物技术公司 |
Melan-a肽类似物-病毒样颗粒偶联物
|
|
CA2518223A1
(en)
|
2003-03-26 |
2004-10-07 |
Ltt Bio-Pharma Co., Ltd. |
Intravenous nanoparticles for targeting drug delivery and sustained drug release
|
|
US7731967B2
(en)
*
|
2003-04-30 |
2010-06-08 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions for inducing immune responses
|
|
US7727969B2
(en)
|
2003-06-06 |
2010-06-01 |
Massachusetts Institute Of Technology |
Controlled release nanoparticle having bound oligonucleotide for targeted delivery
|
|
WO2005014110A1
(en)
|
2003-07-22 |
2005-02-17 |
Cytos Biotechnology Ag |
Cpg-packaged liposomes
|
|
US20050042298A1
(en)
*
|
2003-08-20 |
2005-02-24 |
Pardridge William M. |
Immunonanoparticles
|
|
WO2005037190A2
(en)
*
|
2003-09-03 |
2005-04-28 |
Dendritherapeutics, Inc. |
Multiplex vaccines
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
US20080160089A1
(en)
*
|
2003-10-14 |
2008-07-03 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
CA2558916C
(en)
|
2003-10-20 |
2009-09-22 |
William Marsh Rice University |
Method to fabricate microcapsules from polymers and charged nanoparticles
|
|
WO2005055949A2
(en)
*
|
2003-12-09 |
2005-06-23 |
The Children's Hospital Of Philadelphia |
Sustained release preparations composed of biocompatible complex microparticles
|
|
WO2005101466A2
(en)
*
|
2003-12-19 |
2005-10-27 |
The University Of North Carolina At Chapel Hill |
Methods for fabricating isolated micro- and nano- structures using soft or imprint lithography
|
|
WO2005065418A2
(en)
|
2003-12-31 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides for diagnosis and therapy
|
|
US20070087986A1
(en)
|
2004-01-26 |
2007-04-19 |
Brett Premack |
Compositions and methods for enhancing immunity by chemoattractant adjuvants
|
|
JP2007526253A
(ja)
|
2004-02-19 |
2007-09-13 |
コーリー ファーマシューティカル グループ，インコーポレイテッド |
免疫刺激性ウイルスｒｎａオリゴヌクレオチド
|
|
CA2562283A1
(en)
*
|
2004-04-09 |
2005-11-24 |
3M Innovative Properties Company |
Methods, compositions, and preparations for delivery of immune response modifiers
|
|
ES2246695B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
|
|
US20060017339A1
(en)
*
|
2004-06-03 |
2006-01-26 |
Lalit Chordia |
Brushless canned motor
|
|
EP1767216B1
(en)
|
2004-06-11 |
2012-07-11 |
Riken |
Drug having regulatory cell ligand contained in liposome
|
|
US7713550B2
(en)
|
2004-06-15 |
2010-05-11 |
Andrx Corporation |
Controlled release sodium valproate formulation
|
|
WO2006080951A2
(en)
|
2004-07-01 |
2006-08-03 |
Yale University |
Targeted and high density drug loaded polymeric materials
|
|
WO2006014579A2
(en)
*
|
2004-07-08 |
2006-02-09 |
The Regents Of California |
Enhancing class i antigen presentation with synthetic sequences
|
|
US8017151B2
(en)
*
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
CN1692943A
(zh)
|
2004-09-17 |
2005-11-09 |
四川大学 |
CpG DNA分子抗感染免疫制剂的制备和应用
|
|
GB0421296D0
(en)
|
2004-09-24 |
2004-10-27 |
Angiogene Pharm Ltd |
Bioreductively-activated prodrugs
|
|
ES2625905T3
(es)
|
2004-10-01 |
2017-07-20 |
Midatech Ltd. |
Nanopartículas que comprenden antígenos y adyuvantes capaces de estimular linfocitos T cooperadores
|
|
CA2583389A1
(en)
*
|
2004-10-07 |
2006-04-20 |
Emory University |
Multifunctional nanoparticles conjugates and their use
|
|
WO2007001448A2
(en)
|
2004-11-04 |
2007-01-04 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
JP2008519052A
(ja)
|
2004-11-05 |
2008-06-05 |
ザ ジェネラル ホスピタル コーポレイション |
薬剤によるヒト遊走性細胞の合目的的挙動
|
|
AU2005334819B2
(en)
|
2004-11-15 |
2011-11-24 |
Novartis Vaccines And Diagnostics Inc. |
Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant
|
|
US20060111271A1
(en)
|
2004-11-24 |
2006-05-25 |
Cerny Erich H |
Active and passive immunization against pharmacologically active hapten molecules using a synthetic carrier compound composed of similar elements
|
|
EP1824872B1
(en)
|
2004-12-14 |
2012-02-08 |
Alnylam Pharmaceuticals Inc. |
Rnai modulation of mll-af4 and uses thereof
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
WO2006102395A2
(en)
|
2005-03-22 |
2006-09-28 |
Medstar Health Inc |
Delivery systems and methods for diagnosing and treating cardiovascular diseases
|
|
US20080305161A1
(en)
|
2005-04-13 |
2008-12-11 |
Pfizer Inc |
Injectable depot formulations and methods for providing sustained release of nanoparticle compositions
|
|
AU2006241149A1
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhanced immunostimulatory activity
|
|
MX2007013760A
(es)
|
2005-05-04 |
2008-01-28 |
Noxxon Pharma Ag |
Uso novedoso de spiegelmers.
|
|
EP1906985A4
(en)
*
|
2005-05-10 |
2012-07-11 |
Naomi Balaban |
COMPOSITIONS FOR ADMINISTERING RNAIII-INHIBITING PEPTIDES
|
|
JP2008540558A
(ja)
*
|
2005-05-10 |
2008-11-20 |
エモリー・ユニバーシティ |
ミセルおよび粒子を用いた、活性物質の送達のための新規の戦略
|
|
CA2614049C
(en)
|
2005-07-06 |
2014-12-02 |
Molly S. Shoichet |
Method of biomolecule immobilization on polymers using click-type chemistry
|
|
US20100278725A1
(en)
|
2005-08-12 |
2010-11-04 |
Jiang Liu |
Methods and devices for lymphatic targeting
|
|
WO2007028341A1
(fr)
|
2005-09-09 |
2007-03-15 |
Beijing Diacrid Medical Technology Co., Ltd. |
Nanomicelles servant de medicaments anticancereux a polyethylene phospholipides glycolyles contenant des vinca alcaloides
|
|
WO2007062107A2
(en)
|
2005-11-25 |
2007-05-31 |
Coley Pharmaceutical Gmbh |
Immunostimulatory oligoribonucleotides
|
|
US9393215B2
(en)
|
2005-12-02 |
2016-07-19 |
Novartis Ag |
Nanoparticles for use in immunogenic compositions
|
|
AU2006325225B2
(en)
|
2005-12-14 |
2013-07-04 |
Cytos Biotechnology Ag |
Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
US7842312B2
(en)
|
2005-12-29 |
2010-11-30 |
Cordis Corporation |
Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
|
|
WO2007089870A2
(en)
*
|
2006-01-31 |
2007-08-09 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
US8021689B2
(en)
|
2006-02-21 |
2011-09-20 |
Ecole Polytechnique Federale de Lausanne (“EPFL”) |
Nanoparticles for immunotherapy
|
|
US8431160B2
(en)
|
2006-02-24 |
2013-04-30 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
|
WO2008105773A2
(en)
|
2006-03-31 |
2008-09-04 |
Massachusetts Institute Of Technology |
System for targeted delivery of therapeutic agents
|
|
US20100247653A1
(en)
|
2006-04-11 |
2010-09-30 |
Hans Lautenschlager |
Nanoparticles containing nicotine and/or cotinine, dispersions, and use thereof
|
|
US8367113B2
(en)
|
2006-05-15 |
2013-02-05 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
WO2007137117A2
(en)
|
2006-05-17 |
2007-11-29 |
Massachusetts Institute Of Technology |
Aptamer-directed drug delivery
|
|
SI2032592T1
(sl)
|
2006-06-12 |
2013-10-30 |
Cytos Biotechnology Ag |
Postopki za pakiranje oligonukleotidov v virusu-podobne delce RNA bakteriofagov
|
|
US20080014281A1
(en)
*
|
2006-06-16 |
2008-01-17 |
Florida Atlantic University |
Chitin Micro-Particles As An Adjuvant
|
|
WO2007150030A2
(en)
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
US20100144845A1
(en)
|
2006-08-04 |
2010-06-10 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US20080171059A1
(en)
|
2006-08-07 |
2008-07-17 |
Shanshan Wu Howland |
Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens
|
|
RU2413506C2
(ru)
|
2006-08-11 |
2011-03-10 |
Панацея Биотек Лимитед |
Частицы для доставки активных ингредиентов, способ их получения и композиции из них
|
|
WO2008033432A2
(en)
|
2006-09-12 |
2008-03-20 |
Coley Pharmaceutical Group, Inc. |
Immune modulation by chemically modified ribonucleosides and oligoribonucleotides
|
|
CA2702340C
(en)
|
2006-10-12 |
2014-12-16 |
The University Of Queensland |
Compositions and methods for modulating immune responses
|
|
US20100303723A1
(en)
|
2006-11-20 |
2010-12-02 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
|
WO2008073856A2
(en)
|
2006-12-08 |
2008-06-19 |
Massachusetts Institute Of Technology |
Delivery of nanoparticles and/or agents to cells
|
|
WO2008071774A1
(en)
|
2006-12-14 |
2008-06-19 |
Cytos Biotechnology Ag |
Purification process for coat protein of rna bacteriophages
|
|
US20080149123A1
(en)
*
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
EP2510946B1
(en)
*
|
2007-02-07 |
2015-08-05 |
The Regents of The University of California |
Conjugates of synthetic tlr agonists and uses therefor
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
WO2008115641A2
(en)
|
2007-02-15 |
2008-09-25 |
Yale University |
Modular nanoparticles for adaptable vaccines
|
|
US20100151031A1
(en)
|
2007-03-23 |
2010-06-17 |
Desimone Joseph M |
Discrete size and shape specific organic nanoparticles designed to elicit an immune response
|
|
US11246831B2
(en)
|
2007-03-30 |
2022-02-15 |
Particle Sciences, Inc. |
Particle formulations and uses thereof
|
|
US20090074828A1
(en)
|
2007-04-04 |
2009-03-19 |
Massachusetts Institute Of Technology |
Poly(amino acid) targeting moieties
|
|
WO2008124634A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Polymer-encapsulated reverse micelles
|
|
US20090226525A1
(en)
|
2007-04-09 |
2009-09-10 |
Chimeros Inc. |
Self-assembling nanoparticle drug delivery system
|
|
JP2010523656A
(ja)
|
2007-04-12 |
2010-07-15 |
エモリー・ユニバーシティ |
ミセルおよび粒子を用いた、活性物質の送達のための新規の戦略
|
|
US8394914B2
(en)
|
2007-08-24 |
2013-03-12 |
Board Of Trustees Of Michigan State University |
Functional polyglycolide nanoparticles derived from unimolecular micelles
|
|
WO2009038685A1
(en)
|
2007-09-18 |
2009-03-26 |
The Scripps Research Institute |
Ligands for copper-catalyzed azide-alkyne cycloaddition reactions
|
|
MX2010003642A
(es)
*
|
2007-10-12 |
2010-08-09 |
Massachusetts Inst Technology |
Nanotecnologia de vacuna.
|
|
EP2217930B1
(en)
*
|
2007-10-24 |
2013-03-06 |
Tallinn University Of Technology |
Maldi ms-based high-throughput screening method for substances inhibiting aggregation of alzheimer's amyloid beta peptides
|
|
AU2008335457B2
(en)
*
|
2007-12-07 |
2015-04-16 |
Glaxosmithkline Biologicals S.A. |
Compositions for inducing immune responses
|
|
WO2009109428A2
(en)
|
2008-02-01 |
2009-09-11 |
Alpha-O Peptides Ag |
Self-assembling peptide nanoparticles useful as vaccines
|
|
WO2009106999A2
(en)
|
2008-02-28 |
2009-09-03 |
Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts |
Hollow nanoparticles and uses thereof
|
|
US20110151015A1
(en)
|
2008-03-04 |
2011-06-23 |
Liquikia Technologies, Inc. |
Immunomodulator particles and methods of treating
|
|
US20090297621A1
(en)
|
2008-06-03 |
2009-12-03 |
Abbott Cardiovascular Systems Inc. |
Microparticles For The Treatment Of Disease
|
|
WO2010005726A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences Inc. |
Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
|
|
AU2009268923B2
(en)
*
|
2008-06-16 |
2015-09-17 |
Pfizer Inc. |
Drug loaded polymeric nanoparticles and methods of making and using same
|
|
EP2303236A4
(en)
*
|
2008-07-01 |
2012-09-26 |
Univ Emory |
SYNERGISTIC INDUCTION OF HUMOR AND CELLULAR IMMUNITY BY COMBINATORY ACTIVATION OF TOLL-LIKE RECEPTORS
|
|
WO2010017330A1
(en)
|
2008-08-06 |
2010-02-11 |
Novartis Ag |
Microparticles for use in immunogenic compositions
|
|
UA103195C2
(uk)
*
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
JP5519670B2
(ja)
|
2008-08-11 |
2014-06-11 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
BRPI0917458A2
(pt)
|
2008-08-11 |
2015-12-01 |
Glaxosmithkline Llc |
composto, método de tratamento de doenças e condições, composição farmacêutica, método para tratar ou prevenir doença, e, uso de um composto
|
|
US8323696B2
(en)
*
|
2008-08-29 |
2012-12-04 |
Ecole Polytechnique Federale De Lausanne |
Nanoparticles for immunotherapy
|
|
WO2010039861A2
(en)
|
2008-09-30 |
2010-04-08 |
The Regents Of The University Of Michigan |
Dendrimer conjugates
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US8343498B2
(en)
*
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
US9764012B2
(en)
|
2009-04-01 |
2017-09-19 |
University Of Miami |
Vaccine compositions and methods of use thereof
|
|
AU2010239689A1
(en)
*
|
2009-04-21 |
2011-11-03 |
Selecta Biosciences, Inc. |
Immunonanotherapeutics providing a Th1-biased response
|
|
AU2010242867B2
(en)
|
2009-05-01 |
2016-05-12 |
Qiagen Gaithersburg, Inc. |
A non-target amplification method for detection of RNA splice-forms in a sample
|
|
WO2010138193A2
(en)
|
2009-05-27 |
2010-12-02 |
Selecta Biosciences, Inc. |
Targeted synthetic nanocarriers with ph sensitive release of immunomodulatory agents
|
|
WO2011005850A1
(en)
|
2009-07-07 |
2011-01-13 |
The Research Foundation Of State University Of New York |
Lipidic compositions for induction of immune tolerance
|
|
CN107617110A
(zh)
*
|
2009-08-26 |
2018-01-23 |
西莱克塔生物科技公司 |
诱导t细胞辅助的组合物
|
|
JP5965844B2
(ja)
|
2009-12-15 |
2016-08-10 |
バインド セラピューティックス インコーポレイテッド |
高いガラス転移温度または高分子量のコポリマーを有する治療用ポリマーナノ粒子組成物
|
|
WO2011085231A2
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
US20110229556A1
(en)
|
2010-03-19 |
2011-09-22 |
Massachusetts Institute Of Technology |
Lipid-coated polymer particles for immune stimulation
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
US20110272836A1
(en)
|
2010-04-12 |
2011-11-10 |
Selecta Biosciences, Inc. |
Eccentric vessels
|
|
CN107029223A
(zh)
|
2010-05-26 |
2017-08-11 |
西莱克塔生物科技公司 |
合成纳米载体联合疫苗
|
|
WO2012024621A2
(en)
|
2010-08-20 |
2012-02-23 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza a virus hemagglutinin
|
|
US20120070493A1
(en)
*
|
2010-08-23 |
2012-03-22 |
Selecta Biosciences, Inc. |
Targeted multi-epitope dosage forms for induction of an immune response to antigens
|
|
EP2640190A4
(en)
|
2010-11-05 |
2016-05-11 |
Selecta Biosciences Inc |
MODIFIED NICOTINIC COMPOUNDS AND ASSOCIATED METHODS
|
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
US20120244222A1
(en)
|
2011-03-25 |
2012-09-27 |
Selecta Biosciences, Inc. |
Osmotic mediated release synthetic nanocarriers
|
|
CN107320734A
(zh)
|
2011-04-29 |
2017-11-07 |
西莱克塔生物科技公司 |
从合成纳米载体中控制释放免疫抑制剂
|
|
JP2014521687A
(ja)
*
|
2011-07-29 |
2014-08-28 |
セレクタ バイオサイエンシーズ インコーポレーテッド |
体液性および細胞傷害性ｔリンパ球（ｃｔｌ）免疫応答を生成する合成ナノキャリア
|
|
WO2013036296A1
(en)
*
|
2011-09-06 |
2013-03-14 |
Selecta Biosciences, Inc. |
Compositions and methods for producing antigen-specific induced tolerogenic dendritic cells with synthetic nanocarriers
|
|
CN105307641A
(zh)
|
2013-05-03 |
2016-02-03 |
西莱克塔生物科技公司 |
用于降低不期望体液免疫应答的给药组合
|
|
ES2834129T3
(es)
|
2013-06-04 |
2021-06-16 |
Selecta Biosciences Inc |
Administración repetida de agentes inmunoterapéuticos específicos de antígeno no inmunosupresores
|
|
US20160220501A1
(en)
|
2015-02-03 |
2016-08-04 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
|
US20150359865A1
(en)
|
2014-06-17 |
2015-12-17 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers for t-cell-mediated autoimmune disease
|
|
EP3160453A1
(en)
|
2014-06-25 |
2017-05-03 |
Selecta Biosciences, Inc. |
Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
|
|
EA201790551A1
(ru)
|
2014-09-07 |
2017-07-31 |
Селекта Байосайенсиз, Инк. |
Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору
|
|
AU2015342968B2
(en)
|
2014-11-05 |
2021-05-27 |
Selecta Biosciences, Inc. |
Methods and compositions related to the use of low HLB surfactants in the production of synthetic nanocarriers comprising a rapalog
|