|
FR7461M
(enExample)
|
1968-06-19 |
1970-01-05 |
|
|
|
GB1355961A
(en)
|
1970-02-27 |
1974-06-12 |
Wellcome Found |
Preparation of immunosuppressive antilymphocytic serum
|
|
CH594444A5
(enExample)
*
|
1972-12-04 |
1978-01-13 |
Gerd Birrenbach |
|
|
DK143689C
(da)
|
1975-03-20 |
1982-03-15 |
J Kreuter |
Fremgangsmaade til fremstilling af en adsorberet vaccine
|
|
US4756907A
(en)
|
1978-10-17 |
1988-07-12 |
Stolle Research & Development Corp. |
Active/passive immunization of the internal female reproductive organs
|
|
US4946929A
(en)
|
1983-03-22 |
1990-08-07 |
Massachusetts Institute Of Technology |
Bioerodible articles useful as implants and prostheses having predictable degradation rates
|
|
US6309669B1
(en)
|
1984-03-16 |
2001-10-30 |
The United States Of America As Represented By The Secretary Of The Army |
Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
|
|
US4638045A
(en)
|
1985-02-19 |
1987-01-20 |
Massachusetts Institute Of Technology |
Non-peptide polyamino acid bioerodible polymers
|
|
US4631211A
(en)
|
1985-03-25 |
1986-12-23 |
Scripps Clinic & Research Foundation |
Means for sequential solid phase organic synthesis and methods using the same
|
|
US4806621A
(en)
|
1986-01-21 |
1989-02-21 |
Massachusetts Institute Of Technology |
Biocompatible, bioerodible, hydrophobic, implantable polyimino carbonate article
|
|
JPS63122620A
(ja)
*
|
1986-11-12 |
1988-05-26 |
Sanraku Inc |
ポリ乳酸マイクロスフエア及びその製造方法
|
|
US5736372A
(en)
|
1986-11-20 |
1998-04-07 |
Massachusetts Institute Of Technology |
Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
|
|
US5759830A
(en)
|
1986-11-20 |
1998-06-02 |
Massachusetts Institute Of Technology |
Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
|
|
CA1340581C
(en)
|
1986-11-20 |
1999-06-08 |
Joseph P. Vacanti |
Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
|
|
FR2608988B1
(fr)
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanoparticules
|
|
US5912017A
(en)
|
1987-05-01 |
1999-06-15 |
Massachusetts Institute Of Technology |
Multiwall polymeric microspheres
|
|
US5229490A
(en)
|
1987-05-06 |
1993-07-20 |
The Rockefeller University |
Multiple antigen peptide system
|
|
US5019379A
(en)
|
1987-07-31 |
1991-05-28 |
Massachusetts Institute Of Technology |
Unsaturated polyanhydrides
|
|
US6130082A
(en)
|
1988-05-05 |
2000-10-10 |
American Cyanamid Company |
Recombinant flagellin vaccines
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5010167A
(en)
|
1989-03-31 |
1991-04-23 |
Massachusetts Institute Of Technology |
Poly(amide-and imide-co-anhydride) for biological application
|
|
US5114703A
(en)
|
1989-05-30 |
1992-05-19 |
Alliance Pharmaceutical Corp. |
Percutaneous lymphography using particulate fluorocarbon emulsions
|
|
US5733572A
(en)
*
|
1989-12-22 |
1998-03-31 |
Imarx Pharmaceutical Corp. |
Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
|
|
GB9016885D0
(en)
*
|
1990-08-01 |
1990-09-12 |
Scras |
Sustained release pharmaceutical compositions
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
ATE156705T1
(de)
|
1991-04-02 |
1997-08-15 |
Biotech Australia Pty Ltd |
Systeme zur oralen freisetzung von mikropartikeln
|
|
US5811447A
(en)
*
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
|
US6235313B1
(en)
*
|
1992-04-24 |
2001-05-22 |
Brown University Research Foundation |
Bioadhesive microspheres and their use as drug delivery and imaging systems
|
|
EP0654973A4
(en)
|
1992-07-21 |
1995-08-09 |
Gen Hospital Corp |
ARRANGEMENT FOR DELIVERING MEDICINES TO THE LYMPHIC TISSUE.
|
|
GB9216082D0
(en)
|
1992-07-28 |
1992-09-09 |
Univ Nottingham |
Lymphatic delivery composition
|
|
US6608201B2
(en)
|
1992-08-28 |
2003-08-19 |
3M Innovative Properties Company |
Process for preparing 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2695563B1
(fr)
|
1992-09-11 |
1994-12-02 |
Pasteur Institut |
Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires.
|
|
WO1994007469A1
(en)
|
1992-09-25 |
1994-04-14 |
Dynagen, Inc. |
An immunobooster for delayed release of immunogen
|
|
US5399665A
(en)
|
1992-11-05 |
1995-03-21 |
Massachusetts Institute Of Technology |
Biodegradable polymers for cell transplantation
|
|
CA2153391C
(en)
|
1993-01-11 |
2000-08-15 |
Kenneth Rock |
Inducing cytotoxic t lymphocyte responses
|
|
US5512600A
(en)
|
1993-01-15 |
1996-04-30 |
Massachusetts Institute Of Technology |
Preparation of bonded fiber structures for cell implantation
|
|
US5514378A
(en)
|
1993-02-01 |
1996-05-07 |
Massachusetts Institute Of Technology |
Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
|
|
MX9401351A
(es)
|
1993-02-22 |
1994-08-31 |
Alza Corp |
Composiciones para suministro oral para agentes activos.
|
|
US5916539A
(en)
|
1993-03-02 |
1999-06-29 |
Silica Gel Ges. M.B.H. |
Superparamagnetic particles, process for producing the same and their use
|
|
US5565215A
(en)
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
WO1995003035A1
(en)
|
1993-07-23 |
1995-02-02 |
Massachusetts Institute Of Technology |
Polymerized liposomes with enhanced stability for oral delivery
|
|
US5798340A
(en)
|
1993-09-17 |
1998-08-25 |
Gilead Sciences, Inc. |
Nucleotide analogs
|
|
US5500161A
(en)
|
1993-09-21 |
1996-03-19 |
Massachusetts Institute Of Technology And Virus Research Institute |
Method for making hydrophobic polymeric microparticles
|
|
EP0740548B1
(en)
|
1994-02-28 |
2002-12-04 |
Nanopharm AG |
Drug targeting system, method for preparing same and its use
|
|
GB9412273D0
(en)
*
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
CA2560114A1
(en)
|
1994-07-15 |
1996-02-01 |
The University Of Iowa Research Foundation |
Immunomodulatory oligonucleotides
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6007845A
(en)
|
1994-07-22 |
1999-12-28 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US5716404A
(en)
|
1994-12-16 |
1998-02-10 |
Massachusetts Institute Of Technology |
Breast tissue engineering
|
|
DE69630514D1
(de)
|
1995-01-05 |
2003-12-04 |
Univ Michigan |
Oberflächen-modifizierte nanopartikel und verfahren für ihre herstellung und verwendung
|
|
US6123727A
(en)
|
1995-05-01 |
2000-09-26 |
Massachusetts Institute Of Technology |
Tissue engineered tendons and ligaments
|
|
WO1997004747A1
(en)
|
1995-07-27 |
1997-02-13 |
Dunn James M |
Drug delivery systems for macromolecular drugs
|
|
WO1997007788A2
(en)
|
1995-08-31 |
1997-03-06 |
Alkermes Controlled Therapeutics, Inc. |
Composition for sustained release of an agent
|
|
US6095148A
(en)
|
1995-11-03 |
2000-08-01 |
Children's Medical Center Corporation |
Neuronal stimulation using electrically conducting polymers
|
|
US5902599A
(en)
|
1996-02-20 |
1999-05-11 |
Massachusetts Institute Of Technology |
Biodegradable polymer networks for use in orthopedic and dental applications
|
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
|
US5922695A
(en)
|
1996-07-26 |
1999-07-13 |
Gilead Sciences, Inc. |
Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
|
|
US6767702B2
(en)
|
1996-07-29 |
2004-07-27 |
Nanosphere, Inc. |
Nanoparticles having oligonucleotides attached thereto and uses therefor
|
|
US6368598B1
(en)
*
|
1996-09-16 |
2002-04-09 |
Jcrt Radiation Oncology Support Services, Inc. |
Drug complex for treatment of metastatic prostate cancer
|
|
EP0938315B9
(en)
|
1996-10-25 |
2008-02-20 |
Minnesota Mining And Manufacturing Company |
Immune response modifier compounds for treatment of th2 mediated and related diseases
|
|
US6042820A
(en)
|
1996-12-20 |
2000-03-28 |
Connaught Laboratories Limited |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
|
|
EP1039935A4
(en)
|
1997-02-28 |
2005-04-27 |
Univ Iowa Res Found |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
|
|
EP2172216A3
(en)
|
1997-03-10 |
2010-11-24 |
Ottawa Hospital Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6211159B1
(en)
|
1997-04-11 |
2001-04-03 |
University Of Toronto |
Flagellin gene, FlaC of campylobacter
|
|
US6060082A
(en)
*
|
1997-04-18 |
2000-05-09 |
Massachusetts Institute Of Technology |
Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
|
|
ATE370740T1
(de)
|
1997-05-20 |
2007-09-15 |
Ottawa Health Research Inst |
Verfahren zur herstellung von nukleinsäurekonstrukten
|
|
US5837752A
(en)
|
1997-07-17 |
1998-11-17 |
Massachusetts Institute Of Technology |
Semi-interpenetrating polymer networks
|
|
US6989435B2
(en)
|
1997-09-11 |
2006-01-24 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
DE19745950A1
(de)
|
1997-10-17 |
1999-04-22 |
Dds Drug Delivery Service Ges |
Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation
|
|
ES2205573T3
(es)
*
|
1997-11-28 |
2004-05-01 |
Sumitomo Pharmaceuticals Company, Limited |
Nuevo compuestos heterociclicos.
|
|
US6254890B1
(en)
|
1997-12-12 |
2001-07-03 |
Massachusetts Institute Of Technology |
Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
|
|
US6197229B1
(en)
*
|
1997-12-12 |
2001-03-06 |
Massachusetts Institute Of Technology |
Method for high supercoiled DNA content microspheres
|
|
FR2775435B1
(fr)
*
|
1998-02-27 |
2000-05-26 |
Bioalliance Pharma |
Nanoparticules comprenant au moins un polymere et au moins un compose apte a complexer un ou plusieurs principes actifs
|
|
US6232287B1
(en)
|
1998-03-13 |
2001-05-15 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
US6506577B1
(en)
|
1998-03-19 |
2003-01-14 |
The Regents Of The University Of California |
Synthesis and crosslinking of catechol containing copolypeptides
|
|
US6632922B1
(en)
|
1998-03-19 |
2003-10-14 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
US6686446B2
(en)
|
1998-03-19 |
2004-02-03 |
The Regents Of The University Of California |
Methods and compositions for controlled polypeptide synthesis
|
|
CA2323929C
(en)
|
1998-04-03 |
2004-03-09 |
University Of Iowa Research Foundation |
Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
|
|
WO1999056755A1
(en)
|
1998-05-06 |
1999-11-11 |
University Of Iowa Research Foundation |
Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
|
|
DE19827164A1
(de)
|
1998-06-18 |
1999-12-23 |
Merck Patent Gmbh |
Katalytisch Titan(IV)-oxid vermittelte geminale symmetrische Dialkylierung von Carbonsäureamiden
|
|
US6242589B1
(en)
|
1998-07-14 |
2001-06-05 |
Isis Pharmaceuticals, Inc. |
Phosphorothioate oligonucleotides having modified internucleoside linkages
|
|
DE69930642T2
(de)
|
1998-07-29 |
2006-12-28 |
Chiron Corp., Emeryville |
Mikropartikel mit adsorbenten oberflächen, verfahren zu ihrer herstellung und ihrer verwendung
|
|
DE19839214C1
(de)
|
1998-08-28 |
2000-05-25 |
Aventis Res & Tech Gmbh & Co |
Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung
|
|
US6306640B1
(en)
|
1998-10-05 |
2001-10-23 |
Genzyme Corporation |
Melanoma antigenic peptides
|
|
CA2348871C
(en)
*
|
1998-11-02 |
2009-04-14 |
John G. Devane |
Multiparticulate modified release composition
|
|
US7521068B2
(en)
|
1998-11-12 |
2009-04-21 |
Elan Pharma International Ltd. |
Dry powder aerosols of nanoparticulate drugs
|
|
US7238711B1
(en)
|
1999-03-17 |
2007-07-03 |
Cambridge University Technical Services Ltd. |
Compounds and methods to inhibit or augment an inflammatory response
|
|
US6444192B1
(en)
|
1999-02-05 |
2002-09-03 |
The Regents Of The University Of California |
Diagnostic imaging of lymph structures
|
|
US7238368B2
(en)
|
1999-04-23 |
2007-07-03 |
Alza Corporation |
Releasable linkage and compositions containing same
|
|
US6365179B1
(en)
|
1999-04-23 |
2002-04-02 |
Alza Corporation |
Conjugate having a cleavable linkage for use in a liposome
|
|
US7390780B2
(en)
|
1999-04-23 |
2008-06-24 |
Alza Corporation |
Gene delivery mediated by liposome-DNA complex with cleavable peg surface modification
|
|
US6800296B1
(en)
|
1999-05-19 |
2004-10-05 |
Massachusetts Institute Of Technology |
Modification of surfaces using biological recognition events
|
|
US6815170B1
(en)
|
1999-06-30 |
2004-11-09 |
John Wayne Cancer Institute |
Methods for lymph node identification
|
|
EP1202671A4
(en)
*
|
1999-08-13 |
2004-11-10 |
Point Biomedical Corp |
MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
|
|
CA2391534A1
(en)
|
1999-11-15 |
2001-05-25 |
Drug Innovation & Design, Inc. |
Selective cellular targeting: multifunctional delivery vehicles
|
|
US20050032733A1
(en)
*
|
2001-05-18 |
2005-02-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA)
|
|
US8202979B2
(en)
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
US20050020525A1
(en)
*
|
2002-02-20 |
2005-01-27 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US6632671B2
(en)
|
2000-02-28 |
2003-10-14 |
Genesegues, Inc. |
Nanoparticle encapsulation system and method
|
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
US7129222B2
(en)
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
|
US7192725B2
(en)
|
2000-05-19 |
2007-03-20 |
University Of Toronto |
Flagellin gene, flaC of Campylobacter
|
|
WO2002100325A2
(en)
|
2000-10-13 |
2002-12-19 |
Ligocyte Pharmaceuticals, Inc. |
Polyvalent nanoparticles
|
|
GB0025414D0
(en)
|
2000-10-16 |
2000-11-29 |
Consejo Superior Investigacion |
Nanoparticles
|
|
EP1355965B1
(en)
|
2000-10-19 |
2012-09-19 |
Ecole Polytechnique Fédérale de Lausanne (EPFL) |
Method of synthesizing block copolymers for multifunctional self-assembled systems
|
|
US7592008B2
(en)
|
2000-11-20 |
2009-09-22 |
The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois |
Membrane scaffold proteins
|
|
US7097837B2
(en)
|
2001-02-19 |
2006-08-29 |
Pharmexa A/S |
Synthetic vaccine agents
|
|
US20030175950A1
(en)
|
2001-05-29 |
2003-09-18 |
Mcswiggen James A. |
RNA interference mediated inhibition of HIV gene expression using short interfering RNA
|
|
US7314624B2
(en)
|
2001-06-05 |
2008-01-01 |
The Regents Of The University Of Michigan |
Nanoemulsion vaccines
|
|
CA2452382A1
(en)
|
2001-07-10 |
2003-01-23 |
Corixa Corporation |
Compositions and methods for delivery of proteins and adjuvants encapsulated in microspheres
|
|
CA2456328C
(en)
|
2001-08-07 |
2015-05-26 |
Dynavax Technologies Corporation |
Complexes of a short cpg-containing oligonucleotide bound to the surface of a solid phase microcarrier and methods for use thereof
|
|
US6818732B2
(en)
|
2001-08-30 |
2004-11-16 |
The Regents Of The University Of California |
Transition metal initiators for controlled poly (beta-peptide) synthesis from beta-lactam monomers
|
|
US8088388B2
(en)
|
2002-02-14 |
2012-01-03 |
United Biomedical, Inc. |
Stabilized synthetic immunogen delivery system
|
|
EP2572707A3
(en)
*
|
2002-02-20 |
2013-11-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microparticles with adsorbed polypeptide-containing molecules
|
|
US20030232013A1
(en)
|
2002-02-22 |
2003-12-18 |
Gary Sieckman |
Therapeutic and diagnostic targeting of cancers cells with tumor homing peptides
|
|
US7635463B2
(en)
*
|
2002-02-27 |
2009-12-22 |
Pharmain Corporation |
Compositions for delivery of therapeutics and other materials
|
|
ES2734652T3
(es)
|
2002-04-04 |
2019-12-11 |
Zoetis Belgium S A |
Oligorribonucleótidos inmunoestimulantes que contienen G y U
|
|
US20040038303A1
(en)
*
|
2002-04-08 |
2004-02-26 |
Unger Gretchen M. |
Biologic modulations with nanoparticles
|
|
US20080233181A1
(en)
|
2002-04-12 |
2008-09-25 |
Nagy Jon O |
Nanoparticle adjuvants for sub-unit vaccines
|
|
US7285289B2
(en)
|
2002-04-12 |
2007-10-23 |
Nagy Jon O |
Nanoparticle vaccines
|
|
JP4381826B2
(ja)
*
|
2002-04-22 |
2009-12-09 |
ユニヴァーシティ オヴ フロリダ |
機能化されたナノ粒子及びその使用方法
|
|
WO2003101972A1
(en)
*
|
2002-05-30 |
2003-12-11 |
The Scripps Research Institute |
Copper-catalysed ligation of azides and acetylenes
|
|
US20040092470A1
(en)
|
2002-06-18 |
2004-05-13 |
Leonard Sherry A. |
Dry powder oligonucleotide formualtion, preparation and its uses
|
|
WO2004005325A2
(en)
|
2002-07-10 |
2004-01-15 |
The Ohio State University Research Foundation |
Antigen-polymer compositions
|
|
MXPA04012010A
(es)
*
|
2002-07-18 |
2005-03-07 |
Cytos Biotechnology Ag |
Conjugados de hapteno-portador que comprende particulas similares a virus, y usos de los mismos.
|
|
US7488792B2
(en)
|
2002-08-28 |
2009-02-10 |
Burnham Institute For Medical Research |
Collagen-binding molecules that selectively home to tumor vasculature and methods of using same
|
|
US20060189554A1
(en)
|
2002-09-24 |
2006-08-24 |
Russell Mumper |
Nanoparticle-Based vaccine delivery system containing adjuvant
|
|
US7008411B1
(en)
|
2002-09-30 |
2006-03-07 |
Advanced Cardiovascular Systems, Inc. |
Method and apparatus for treating vulnerable plaque
|
|
NO20024755D0
(no)
|
2002-10-03 |
2002-10-03 |
Amersham Health As |
Metode
|
|
SE0203687D0
(sv)
*
|
2002-12-13 |
2002-12-13 |
Ian Harwigsson Med Adagit Fa |
Pharmaceutical Porous Particles
|
|
US20040156846A1
(en)
|
2003-02-06 |
2004-08-12 |
Triton Biosystems, Inc. |
Therapy via targeted delivery of nanoscale particles using L6 antibodies
|
|
JP4509999B2
(ja)
|
2003-02-17 |
2010-07-21 |
ブルクハルト，ペーター |
医薬送達及び抗原提示システムとしてのペプチドナノ粒子
|
|
US20040191215A1
(en)
|
2003-03-25 |
2004-09-30 |
Michael Froix |
Compositions for induction of a therapeutic response
|
|
CN100361651C
(zh)
|
2003-03-26 |
2008-01-16 |
日本株式会社Ltt生物医药 |
用于靶向药物送递和持续药物释放的静脉内纳米颗粒
|
|
CN100560719C
(zh)
|
2003-03-26 |
2009-11-18 |
赛托斯生物技术公司 |
Melan-a肽类似物-病毒样颗粒偶联物
|
|
US7731967B2
(en)
*
|
2003-04-30 |
2010-06-08 |
Novartis Vaccines And Diagnostics, Inc. |
Compositions for inducing immune responses
|
|
US7727969B2
(en)
|
2003-06-06 |
2010-06-01 |
Massachusetts Institute Of Technology |
Controlled release nanoparticle having bound oligonucleotide for targeted delivery
|
|
WO2005014110A1
(en)
|
2003-07-22 |
2005-02-17 |
Cytos Biotechnology Ag |
Cpg-packaged liposomes
|
|
US20050042298A1
(en)
|
2003-08-20 |
2005-02-24 |
Pardridge William M. |
Immunonanoparticles
|
|
EP1670509A4
(en)
*
|
2003-09-03 |
2007-10-31 |
Dendritherapeutics Inc |
MULTIPLEX VACCINES
|
|
US7943179B2
(en)
|
2003-09-23 |
2011-05-17 |
Massachusetts Institute Of Technology |
pH triggerable polymeric particles
|
|
US20080160089A1
(en)
*
|
2003-10-14 |
2008-07-03 |
Medivas, Llc |
Vaccine delivery compositions and methods of use
|
|
US7829119B2
(en)
|
2003-10-20 |
2010-11-09 |
William Marsh Rice University |
Method to fabricate microcapsules from polymers and charged nanoparticles
|
|
US20070116768A1
(en)
|
2003-12-09 |
2007-05-24 |
Michael Chorny |
Sustained release preparations composed of biocompatible complex microparticles
|
|
CA2549341C
(en)
|
2003-12-19 |
2014-06-10 |
The University Of North Carolina At Chapel Hill |
Methods for fabricating isolated micro- and nano- structures using soft or imprint lithography
|
|
WO2005065418A2
(en)
|
2003-12-31 |
2005-07-21 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides for diagnosis and therapy
|
|
US20070087986A1
(en)
*
|
2004-01-26 |
2007-04-19 |
Brett Premack |
Compositions and methods for enhancing immunity by chemoattractant adjuvants
|
|
TW200533750A
(en)
|
2004-02-19 |
2005-10-16 |
Coley Pharm Group Inc |
Immunostimulatory viral RNA oligonucleotides
|
|
AU2005244260B2
(en)
*
|
2004-04-09 |
2010-08-05 |
3M Innovative Properties Company |
Methods, compositions, and preparations for delivery of immune response modifiers
|
|
ES2246695B1
(es)
|
2004-04-29 |
2007-05-01 |
Instituto Cientifico Y Tecnologico De Navarra, S.A. |
Composicion estimuladora de la respuesta inmunitaria que comprende nanoparticulas a base de un copolimero de metil vinil eter y anhidrido maleico.
|
|
US20060017339A1
(en)
*
|
2004-06-03 |
2006-01-26 |
Lalit Chordia |
Brushless canned motor
|
|
PT1767216E
(pt)
|
2004-06-11 |
2012-08-27 |
Riken |
Fármaco tendo um ligando de células reguladoras contido num lipossoma
|
|
US7713550B2
(en)
|
2004-06-15 |
2010-05-11 |
Andrx Corporation |
Controlled release sodium valproate formulation
|
|
WO2006080951A2
(en)
*
|
2004-07-01 |
2006-08-03 |
Yale University |
Targeted and high density drug loaded polymeric materials
|
|
WO2006014579A2
(en)
*
|
2004-07-08 |
2006-02-09 |
The Regents Of California |
Enhancing class i antigen presentation with synthetic sequences
|
|
US8017151B2
(en)
|
2004-09-07 |
2011-09-13 |
Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center |
Amphiphilic polymer-protein conjugates and methods of use thereof
|
|
CN1692943A
(zh)
|
2004-09-17 |
2005-11-09 |
四川大学 |
CpG DNA分子抗感染免疫制剂的制备和应用
|
|
GB0421296D0
(en)
|
2004-09-24 |
2004-10-27 |
Angiogene Pharm Ltd |
Bioreductively-activated prodrugs
|
|
US9079765B2
(en)
*
|
2004-10-01 |
2015-07-14 |
Midatech Ltd. |
Nanoparticles comprising antigens and adjuvants, and immunogenic structures
|
|
WO2006042146A2
(en)
*
|
2004-10-07 |
2006-04-20 |
Emory University |
Multifunctional nanoparticles conjugates and their use
|
|
WO2007001448A2
(en)
|
2004-11-04 |
2007-01-04 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
|
WO2006137934A2
(en)
|
2004-11-05 |
2006-12-28 |
The General Hospital Corporation |
Purposeful movement of human migratory cells away from an agent source
|
|
EP1812056B1
(en)
|
2004-11-15 |
2013-08-07 |
Novartis Vaccines and Diagnostics, Inc. |
Immunogenic compositions containing anthrax antigen, biodegradable polymer microparticles, and polynucleotide-containing immunological adjuvant
|
|
US20060111271A1
(en)
|
2004-11-24 |
2006-05-25 |
Cerny Erich H |
Active and passive immunization against pharmacologically active hapten molecules using a synthetic carrier compound composed of similar elements
|
|
CA2590768A1
(en)
|
2004-12-14 |
2006-06-22 |
Alnylam Pharmaceuticals, Inc. |
Rnai modulation of mll-af4 and uses thereof
|
|
US20060257359A1
(en)
|
2005-02-28 |
2006-11-16 |
Cedric Francois |
Modifying macrophage phenotype for treatment of disease
|
|
WO2006102395A2
(en)
|
2005-03-22 |
2006-09-28 |
Medstar Health Inc |
Delivery systems and methods for diagnosing and treating cardiovascular diseases
|
|
US20080305161A1
(en)
|
2005-04-13 |
2008-12-11 |
Pfizer Inc |
Injectable depot formulations and methods for providing sustained release of nanoparticle compositions
|
|
US20060241076A1
(en)
|
2005-04-26 |
2006-10-26 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhanced immunostimulatory activity
|
|
AU2006243334A1
(en)
|
2005-05-04 |
2006-11-09 |
Noxxon Pharma Ag |
Novel use of spiegelmers
|
|
US20070092575A1
(en)
*
|
2005-05-10 |
2007-04-26 |
Naomi Balaban |
Compositions for administering RNAIII-inhibiting peptides
|
|
US20100062968A1
(en)
*
|
2005-05-10 |
2010-03-11 |
Bali Pulendran |
Novel strategies for delivery of active agents using micelles and particles
|
|
US9290617B2
(en)
|
2005-07-06 |
2016-03-22 |
Molly S. Shoichet |
Method of biomolecule immobilization on polymers using click-type chemistry
|
|
CN101287507B
(zh)
|
2005-08-12 |
2012-12-05 |
刘江 |
用于淋巴靶向的方法和装置
|
|
WO2007028341A1
(fr)
*
|
2005-09-09 |
2007-03-15 |
Beijing Diacrid Medical Technology Co., Ltd. |
Nanomicelles servant de medicaments anticancereux a polyethylene phospholipides glycolyles contenant des vinca alcaloides
|
|
BRPI0622298A8
(pt)
|
2005-11-25 |
2016-04-05 |
Coley Pharm Gmbh |
Oligorribonucleotídeo para estimular a produção de uma citocina pró-inflamatória, uso do mesmo e composição contendo tal oligorribonucleotídeo
|
|
EP1954252B1
(en)
|
2005-12-02 |
2016-02-03 |
GlaxoSmithKline Biologicals SA |
Nanoparticles for use in immunogenic compositions
|
|
JP5484732B2
(ja)
|
2005-12-14 |
2014-05-07 |
サイトス バイオテクノロジー アーゲー |
過敏症の治療のための免疫賦活性核酸パッケージ粒子
|
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
|
US7842312B2
(en)
|
2005-12-29 |
2010-11-30 |
Cordis Corporation |
Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same
|
|
EP1986685A4
(en)
|
2006-01-31 |
2009-02-25 |
Medivas Llc |
COMPOSITIONS FOR DISPENSING A VACCINATE AND METHOD FOR THE APPLICATION THEREOF
|
|
US8021689B2
(en)
|
2006-02-21 |
2011-09-20 |
Ecole Polytechnique Federale de Lausanne (“EPFL”) |
Nanoparticles for immunotherapy
|
|
AU2007221154A1
(en)
|
2006-02-24 |
2007-09-07 |
Novartis Ag |
Microparticles containing biodegradable polymer and cationic polysaccharide for use in immunogenic compositions
|
|
CA2648099C
(en)
|
2006-03-31 |
2012-05-29 |
The Brigham And Women's Hospital, Inc |
System for targeted delivery of therapeutic agents
|
|
WO2007118653A2
(de)
|
2006-04-11 |
2007-10-25 |
Koko Kosmetikvertrieb Gmbh & Co. Kg |
Nanopartikel, enthaltend nicotin und/oder cotinin, dispersionen und die verwendung derselben
|
|
US8367113B2
(en)
*
|
2006-05-15 |
2013-02-05 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
|
WO2007137117A2
(en)
|
2006-05-17 |
2007-11-29 |
Massachusetts Institute Of Technology |
Aptamer-directed drug delivery
|
|
KR101552227B1
(ko)
|
2006-06-12 |
2015-09-10 |
사이토스 바이오테크놀로지 아게 |
올리고뉴클레오티드를 ｒｎａ 박테리오파지의 바이러스-유사 입자로 패키징하는 방법
|
|
WO2008054892A2
(en)
*
|
2006-06-16 |
2008-05-08 |
Florida Atlantic University |
Chitin micro-particles as an adjuvant
|
|
US9381477B2
(en)
*
|
2006-06-23 |
2016-07-05 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
|
WO2008019142A2
(en)
|
2006-08-04 |
2008-02-14 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
|
US20080171059A1
(en)
|
2006-08-07 |
2008-07-17 |
Shanshan Wu Howland |
Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens
|
|
CN101500937A
(zh)
|
2006-08-11 |
2009-08-05 |
万能药生物有限公司 |
用于递送活性成分的粒子及其制备方法和组合物
|
|
WO2008033432A2
(en)
|
2006-09-12 |
2008-03-20 |
Coley Pharmaceutical Group, Inc. |
Immune modulation by chemically modified ribonucleosides and oligoribonucleotides
|
|
CA2702340C
(en)
|
2006-10-12 |
2014-12-16 |
The University Of Queensland |
Compositions and methods for modulating immune responses
|
|
WO2008147456A2
(en)
|
2006-11-20 |
2008-12-04 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
|
US20080213377A1
(en)
|
2006-12-08 |
2008-09-04 |
Bhatia Sangeeta N |
Delivery of Nanoparticles and/or Agents to Cells
|
|
WO2008071774A1
(en)
|
2006-12-14 |
2008-06-19 |
Cytos Biotechnology Ag |
Purification process for coat protein of rna bacteriophages
|
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
|
JP5425642B2
(ja)
*
|
2007-02-07 |
2014-02-26 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
合成ｔｌｒアゴニストの結合体およびそのための使用
|
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
|
WO2008115641A2
(en)
|
2007-02-15 |
2008-09-25 |
Yale University |
Modular nanoparticles for adaptable vaccines
|
|
WO2008118861A2
(en)
|
2007-03-23 |
2008-10-02 |
The University Of North Carolina At Chapel Hill |
Discrete size and shape specific organic nanoparticles designed to elicit an immune response
|
|
EP2142216B1
(en)
|
2007-03-30 |
2015-04-22 |
Particle Sciences, Inc. |
Particle formulations and uses thereof
|
|
JP2010523595A
(ja)
|
2007-04-04 |
2010-07-15 |
マサチューセッツ インスティテュート オブ テクノロジー |
ポリ（アミノ酸）ターゲッティング部分
|
|
WO2008124634A1
(en)
|
2007-04-04 |
2008-10-16 |
Massachusetts Institute Of Technology |
Polymer-encapsulated reverse micelles
|
|
CA2683063A1
(en)
|
2007-04-09 |
2008-10-16 |
Chimeros, Inc. |
Self-assembling nanoparticle drug delivery system
|
|
WO2008127532A1
(en)
|
2007-04-12 |
2008-10-23 |
Emory University |
Novel strategies for delivery of active agents using micelles and particles
|
|
US8394914B2
(en)
|
2007-08-24 |
2013-03-12 |
Board Of Trustees Of Michigan State University |
Functional polyglycolide nanoparticles derived from unimolecular micelles
|
|
WO2009038685A1
(en)
|
2007-09-18 |
2009-03-26 |
The Scripps Research Institute |
Ligands for copper-catalyzed azide-alkyne cycloaddition reactions
|
|
CA2917512C
(en)
|
2007-10-12 |
2025-08-05 |
President And Fellows Of Harvard College |
VACCINE NANOTECHNOLOGY
|
|
WO2009052837A2
(en)
*
|
2007-10-24 |
2009-04-30 |
Tallinn University Of Technology |
Maldi ms-based high-throughput screening method for substances inhibiting aggregation of alzheimer's amyloid beta peptides
|
|
ES2664753T3
(es)
*
|
2007-12-07 |
2018-04-23 |
Glaxosmithkline Biologicals Sa |
Composiciones de inducción de respuestas inmunes
|
|
AU2009221419B2
(en)
|
2008-02-01 |
2013-09-26 |
Alpha-O Peptides Ag |
Self-assembling peptide nanoparticles useful as vaccines
|
|
EP2262489A2
(en)
|
2008-02-28 |
2010-12-22 |
Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts |
Hollow nanoparticles and uses thereof
|
|
JP2011525477A
(ja)
|
2008-03-04 |
2011-09-22 |
リクイディア・テクノロジーズ・インコーポレーテッド |
免疫調節剤粒子および処置方法
|
|
US20090297621A1
(en)
|
2008-06-03 |
2009-12-03 |
Abbott Cardiovascular Systems Inc. |
Microparticles For The Treatment Of Disease
|
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
|
DK2774608T3
(da)
*
|
2008-06-16 |
2020-01-13 |
Pfizer |
Lægemiddelladede polymere nanopartikler og fremgangsmåder til fremstilling og anvendelse deraf
|
|
EP2303236A4
(en)
*
|
2008-07-01 |
2012-09-26 |
Univ Emory |
SYNERGISTIC INDUCTION OF HUMOR AND CELLULAR IMMUNITY BY COMBINATORY ACTIVATION OF TOLL-LIKE RECEPTORS
|
|
JP5667566B2
(ja)
|
2008-08-06 |
2015-02-12 |
ノバルティス アーゲー |
免疫原性組成物における使用のための微粒子
|
|
JP5519670B2
(ja)
|
2008-08-11 |
2014-06-11 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
|
WO2010018132A1
(en)
|
2008-08-11 |
2010-02-18 |
Smithkline Beecham Corporation |
Compounds
|
|
EP2324025A1
(en)
|
2008-08-11 |
2011-05-25 |
Smithkline Beecham Corporation |
Purine derivatives for use in the treatment of allergic, inflammatory and infectious diseases
|
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
|
US8323696B2
(en)
|
2008-08-29 |
2012-12-04 |
Ecole Polytechnique Federale De Lausanne |
Nanoparticles for immunotherapy
|
|
WO2010039861A2
(en)
|
2008-09-30 |
2010-04-08 |
The Regents Of The University Of Michigan |
Dendrimer conjugates
|
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
|
US8343498B2
(en)
*
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
|
US8343497B2
(en)
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
|
JP5661735B2
(ja)
|
2009-04-01 |
2015-01-28 |
ユニバーシティ オブ マイアミ |
ワクチン組成物及びその使用方法
|
|
US20110223201A1
(en)
*
|
2009-04-21 |
2011-09-15 |
Selecta Biosciences, Inc. |
Immunonanotherapeutics Providing a Th1-Biased Response
|
|
EP2425019B1
(en)
|
2009-05-01 |
2014-03-19 |
QIAGEN Gaithersburg, Inc. |
A non-target amplification method for detection of rna splice-forms in a sample
|
|
WO2010138193A2
(en)
*
|
2009-05-27 |
2010-12-02 |
Selecta Biosciences, Inc. |
Targeted synthetic nanocarriers with ph sensitive release of immunomodulatory agents
|
|
EP3058953A1
(en)
|
2009-07-07 |
2016-08-24 |
The Research Foundation Of State University Of New York |
Lipidic compositions for induction of immune tolerance
|
|
EP3311833A3
(en)
*
|
2009-08-26 |
2018-07-25 |
Selecta Biosciences, Inc. |
Compositions that induce t cell help
|
|
US9295649B2
(en)
|
2009-12-15 |
2016-03-29 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers
|
|
WO2011085231A2
(en)
|
2010-01-08 |
2011-07-14 |
Selecta Biosciences, Inc. |
Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
|
|
US20110229556A1
(en)
|
2010-03-19 |
2011-09-22 |
Massachusetts Institute Of Technology |
Lipid-coated polymer particles for immune stimulation
|
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
|
US20110272836A1
(en)
|
2010-04-12 |
2011-11-10 |
Selecta Biosciences, Inc. |
Eccentric vessels
|
|
WO2011150264A2
(en)
|
2010-05-26 |
2011-12-01 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier combination vaccines
|
|
WO2012024629A1
(en)
|
2010-08-20 |
2012-02-23 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising proteins obtained or derived from human influenza a virus hemagglutinin
|
|
AU2011293508A1
(en)
*
|
2010-08-23 |
2013-01-24 |
Selecta Biosciences, Inc. |
Targeted multi-epitope dosage forms for induction of an immune response to antigens
|
|
WO2012061717A1
(en)
|
2010-11-05 |
2012-05-10 |
Selecta Biosciences, Inc. |
Modified nicotinic compounds and related methods
|
|
US20120171229A1
(en)
|
2010-12-30 |
2012-07-05 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers with reactive groups that release biologically active agents
|
|
CA2830948A1
(en)
|
2011-03-25 |
2012-10-04 |
Selecta Biosciences, Inc. |
Osmotic mediated release synthetic nanocarriers
|
|
MX373641B
(es)
|
2011-04-29 |
2020-05-04 |
Selecta Biosciences Inc |
Nanoportadores sintéticos tolerogénicos para la terapia contra alergias.
|
|
CA2843274A1
(en)
|
2011-07-29 |
2013-02-07 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers that generate humoral and cytotoxic t lymphocyte (ctl) immune responses
|
|
US20130058970A1
(en)
|
2011-09-06 |
2013-03-07 |
Selecta Biosciences, Inc. |
Induced tolerogenic dendritic cells to reduce systemic inflammatory cytokines
|
|
CN105283175A
(zh)
|
2013-05-03 |
2016-01-27 |
西莱克塔生物科技公司 |
用于降低的或增强的药效学作用的致耐受性合成纳米载体和治疗性大分子
|
|
EA201592273A1
(ru)
|
2013-06-04 |
2016-09-30 |
Селекта Байосайенсиз, Инк. |
Повторное введение неиммуносупрессивных антигенспецифических иммунотерапевтических средств
|
|
US20150359865A1
(en)
|
2014-06-17 |
2015-12-17 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers for t-cell-mediated autoimmune disease
|
|
US20160220501A1
(en)
|
2015-02-03 |
2016-08-04 |
Selecta Biosciences, Inc. |
Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins
|
|
WO2015200728A1
(en)
|
2014-06-25 |
2015-12-30 |
Selecta Biosciences, Inc. |
Methods and compositions for treatment with synthetic nanocarriers and immune checkpoint inhibitors
|
|
KR20170045344A
(ko)
|
2014-09-07 |
2017-04-26 |
셀렉타 바이오사이언시즈, 인크. |
항-바이러스 전달 벡터 면역 반응을 약화시키기 위한 방법 및 조성물
|
|
IL283699B
(en)
|
2014-11-05 |
2022-09-01 |
Selecta Biosciences Inc |
Methods and preparations related to artificial nanocarriers with rapamycin in a super-saturated steady state
|