JP2015526235A - 液剤移送デバイス - Google Patents
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- 238000002347 injection Methods 0.000 claims description 83
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- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
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Abstract
Description
11…バレル
12…プランジャロッド
13…雄ルアーロックコネクタ
20,20A,20B…薬瓶
21…薬瓶軸線
22…薬瓶本体
23…薬瓶基部
24…薬瓶ヘッド
26…薬瓶開口部
27…薬瓶ネック
28…薬瓶内部
29…薬剤
31…薬瓶ストッパ
32…最上部薬瓶面
33…薬瓶閉鎖部
40…輸液容器
40A,40B…輸液バッグ
41,41A,41B…注入ポート
42…投与ポート
43…液体内容物
44,44A,44B…注入ポート先端
46,46A…自己シールプラグ
47,47A…プラグ表面
48,48A,48B…注入ポート先端リム
49…ツイストオフキャップ
100…液剤移送デバイス
101…雌ルアーコネクタ
102…穿刺部材
110…液剤移送デバイス
111…液体移送部材
112…雌ルアーコネクタ
113…穿刺カニューレ
114…シース
120…液剤移送デバイス
121…流体制御デバイス
130…液剤移送デバイス
131…液剤移送デバイス軸線
132…注入ポートアダプタ
133…液体移送部材
134…針
136…穿刺先端
137…ドリル状ビット
138…ピン
139A,139B…ストッパ
141…内表面
142,142A,142B…フランジ
150…液剤移送デバイス
151…開口
152A…基端
152B…先端
153…穿刺先端
154…シース
160…液剤移送デバイス
161…ハウジング
162…ハウジング軸線
163…アクセス開口
164…バイアルアダプタ
166…針
167…穿刺部材
200A,200B,200C,200D,200E…汎用薬瓶アダプタ
201…薬瓶アダプタ軸線
202…スカート
203…薬瓶空洞
204…頂壁
206…中央部分
207,208…ストラット
209…撓み部材支持部
209A…基端
209B…先端
211,212,213…撓み部材支持部
211A,212A,213A…基端
211B,212B,213B…先端
214…環状支持部
216,217,218,219…横材
221,222,223,224…撓み部材
221A,222A,223A,224A…撓み部材自由端
221B,222B,223B,224B…薬瓶把持部
226…リテーナ構成
227…ステム
228…トラック
230,231,231A,231B…小さい撓み部材
230…注入ポートコネクタ
231…コネクタ軸線
232…支持リング
232A,232B…小さい撓み部材自由端
233…水平面
233A,233B…リム
234,236,237,236A,236B,237A,237B…大きい撓み部材
238…窓
239…リム
241,241A,241B…間隔
250…汎用注入ポートコネクタ
251…コネクタ軸線
252…支持リング
253…水平面
254…コネクタ部材
256…自由端
257…コネクタ開口
300…薬瓶解放道具
301…道具軸線
302…ハウジング
303…周壁
304…底壁
306…頂部リム
307…内表面
308…スロット
309…ストッパ
311…開口
312…レール
313…解放部材
314…解放部材リム
Claims (13)
- 小型の薬瓶および大型の薬瓶の薬瓶とともに使用するための液剤移送デバイスであって、
前記薬瓶は、薬瓶ボトルと、薬瓶内部と、薬瓶ストッパと、最上部薬瓶面と、薬瓶閉鎖部と、を備え、
前記小型の薬瓶は、外径D1を有する薬瓶閉鎖部を備え、
前記大型の薬瓶は、外径D2を有する薬瓶閉鎖部を備え、
前記D1および前記D2は、D2>D1を満たし、
前記液剤移送デバイスは、長手方向の薬瓶アダプタ軸線と、前記薬瓶閉鎖部に入れ子式に固定するためのスカートと、を有する汎用薬瓶アダプタを備え、
前記スカートは、大型の薬瓶の少なくとも頂部を、前記スカートの中に入れ子式にぴったりと受け入れるための薬瓶空洞を形成するために、
前記長手方向の薬瓶アダプタ軸線に交差する頂壁と、
離間して軸線方向に向けられた第1の対の撓み部材支持部と、
前記軸線方向に向けられた第1の対の撓み部材支持部に対向し、離間して軸線方向に向けられた第2の対の撓み部材支持部と
を備え、
前記撓み部材支持部の各々は、前記頂壁に隣接する基端と、前記頂壁から離れた先端と、を有し、
前記第1の対の撓み部材支持部は、該撓み部材支持部に対応する先端同士の間を延在する第1の横材を備え、
前記第1の横材は、前記長手方向の薬瓶アダプタ軸線に対して弾性的に撓むように前記第1の横材に取り付けられた、軸線方向に向けられた第1の撓み部材と一体的に形成され、
前記第1の撓み部材は、前記第1の横材から離れた第1の撓み部材自由端と、該第1の撓み部材自由端の方へ向かう半径方向内向きの第1の薬瓶把持部と、を有し、
前記第2の対の撓み部材支持部は、該撓み部材支持部に対応する先端同士の間を延在する第2の横材を備え、
前記第2の横材は、前記長手方向の薬瓶アダプタ軸線に対して弾性的に撓むように前記第2の横材に取り付けられた、軸線方向に向けられた第2の撓み部材と一体的に形成され、
前記第2の撓み部材は、前記横材から離れた第2の撓み部材自由端と、該第2の撓み部材自由端の方へ向かう半径方向内向きの第2の薬瓶把持部と、を有し、
前記第1の撓み部材と前記第2の撓み部材とは、前記第1の薬瓶把持部および前記第2の薬瓶把持部が該第1の薬瓶把持部と該第2の薬瓶把持部との間にS<D1を満たす間隔Sを形成し、前記汎用薬瓶アダプタを前記薬瓶に入れ子式に固定するときに前記第1の薬瓶把持部および前記第2の薬瓶把持部が薬瓶閉鎖部の下に位置するように、対向し、
前記第1の撓み部材および前記第2の撓み部材は、前記汎用薬瓶アダプタを前記大型の薬瓶に入れ子式に固定するときには、前記汎用薬瓶アダプタを前記小型の薬瓶に入れ子式に固定する場合と比べて、前記第1の横材および前記第2の横材のところで、前記長手方向の薬瓶アダプタ軸線に対して、より大きく、対応して外向きに弾性的に撓まされる
液剤移送デバイス。 - 請求項1に記載のデバイスであって、
前記スカートは、単一の連続的な環状支持部を備え、
前記環状支持部は、前記第1の横材と、前記第2の横材と、前記第1の横材と前記第2の横材との間を延在する第3の横材と、前記第1の横材と前記第2の横材との間を延在するとともに前記第3の横材に対向する第4の横材と、を備え、
前記第3の横材は、前記長手方向の薬瓶アダプタ軸線に対して弾性的に撓むように前記第3の横材に取り付けられた、軸線方向に向けられた第3の撓み部材と一体的に形成され、
前記第3の撓み部材は、前記第3の横材から離れた第3の撓み部材自由端と、該第3の撓み部材自由端の方へ向かう半径方向内向きの第3の薬瓶把持部と、を有し、
前記第4の横材は、前記長手方向の薬瓶アダプタ軸線に対して弾性的に撓むように前記第4の横材に取り付けられた、軸線方向に向けられた第4の撓み部材と一体的に形成され、
前記第4の撓み部材は、前記第4の横材から離れた第4の撓み部材自由端と、該第4の撓み部材自由端の方へ向かう半径方向内向きの第4の薬瓶把持部と、を有し、
前記第3の撓み部材と前記第4の撓み部材とは、前記第3の薬瓶把持部と前記第4の薬瓶把持部との間に前記間隔Sが形成され、前記汎用薬瓶アダプタを前記薬瓶に入れ子式に固定するときに前記第3の薬瓶把持部および前記第4の薬瓶把持部が前記薬瓶閉鎖部の下に位置するように、対向する
デバイス。 - 請求項1または請求項2に記載のデバイスであって、
前記頂面は、環状の中央部分と、前記環状の中央部分から前記撓み部材支持部の各々までの半径方向のストラットと、によって構成される
デバイス。 - 請求項1ないし請求項3のいずれか一項に記載のデバイスであって、
前記第1の撓み部材および前記第2の撓み部材は、
前記第1の撓み部材および前記第2の撓み部材が、前記汎用薬瓶アダプタを小型の薬瓶に入れ子式に固定するときは、前記長手方向の薬瓶アダプタ軸線に略平行となり、前記汎用薬瓶アダプタを大型の薬瓶に入れ子式に固定するときは、前記長手方向の薬瓶アダプタ軸線に対して外向きに撓むように、
前記汎用薬瓶アダプタが薬瓶に入れ子式に固定される前には、前記長手方向の薬瓶アダプタ軸線に略平行である
デバイス。 - 請求項1ないし請求項4のいずれか一項に記載のデバイスであって、
前記頂壁は、
一体的なアクセスポートと、
前記汎用薬瓶アダプタを前記薬瓶に入れ子式に固定するときに薬瓶ストッパを穿刺して前記薬瓶内部と流れ連通することを可能にするための、前記一体的なアクセスポートと流れ連通する一体的な穿刺部材と
を備えるデバイス。 - 請求項1ないし請求項4のいずれか一項に記載のデバイスであって、
前記汎用薬瓶アダプタは、事前に取り付けられた初期の無傷の薬瓶に入れ子式に固定されることができ、
前記頂壁は、前記事前に取り付けられた初期の無傷の薬瓶の前記最上部薬瓶面の上に位置する、軸線方向に向けられた管状のステムを備え、
前記液剤移送デバイスは、さらに、前記ステムに配置された穿刺先端を有する分離した液体移送部材であって、前記薬瓶内部との流れ連通を可能にするために、前記液体移送部材を前記薬瓶の方へ下方に押したときに前記薬瓶ストッパを穿刺するための液体移送部材を備える
デバイス。 - 請求項6に記載のデバイスであって、
前記事前に取り付けられた無傷の薬瓶は、前記第1の撓み部材および前記第2の撓み部材を前記長手方向の薬瓶アダプタ軸線に対して外向きに撓ませるための薬瓶解放道具を使用する場合に、前記汎用薬瓶アダプタから無傷で取り外すことができる
デバイス。 - 小型の薬瓶および大型の薬瓶の薬瓶とともに使用するための液剤移送デバイスであって、
前記薬瓶は、薬瓶ボトルと、薬瓶内部と、薬瓶ストッパと、最上部薬瓶面と、薬瓶閉鎖部と、を備え、
前記小型の薬瓶は、外径D1を有する薬瓶閉鎖部を有し、
前記大型の薬瓶は、外径D2を有する薬瓶閉鎖部を有し、
前記D1およびD2は、D2>D1を満たし、
前記液剤移送デバイスは、長手方向の薬瓶アダプタ軸線と、前記薬瓶に入れ子式に固定するためのスカートと、を有する汎用薬瓶アダプタを備え、
前記スカートは、前記長手方向の薬瓶アダプタ軸線に交差する頂壁を備え、
軸線方向に向けられた一組の小さい撓み部材が、小型の薬瓶の薬瓶閉鎖部に入れ子式に取り付けるために、前記頂壁から下方に垂下し、
前記軸線方向に向けられた一組の小さい撓み部材の各々は、前記頂壁から先端側の小さい撓み部材自由端を有し、
軸線方向に向けられた一組の大きい撓み部材が、大型の薬瓶の薬瓶閉鎖部に入れ子式に取り付けるために、前記頂壁から下方に垂下し、前記軸線方向に向けられた一組の小さい撓み部材を取り囲み、前記大型薬瓶の前記最上部薬瓶面は、前記小さい撓み部材自由端の下に位置する
液剤移送デバイス。 - 請求項8に記載のデバイスであって、
前記軸線方向に向けられた一組の大きい撓み部材は、前記軸線方向に向けられた一組の小さい撓み部材に直交し、それによって、前記汎用薬瓶アダプタを小型の薬瓶に入れ子式に固定するときに、前記軸線方向に向けられた一組の小さい撓み部材は、前記軸線方向に向けられた一組の大きい撓み部材同士の間で、前記長手方向の薬瓶アダプタ軸線に対して外向きに撓む
デバイス。 - 請求項9に記載のデバイスであって、
前記軸線方向に向けられた一組の大きい撓み部材は、隣接する大きい撓み部材の第1の対と、隣接する大きい撓み部材の第2の対と、を備える
デバイス。 - 請求項8ないし請求項10のいずれか一項に記載のデバイスであって、
前記頂壁は、
一体的なアクセスポートと、
前記汎用薬瓶アダプタを前記薬瓶に入れ子式に固定するときに薬瓶ストッパを穿刺して前記薬瓶内部と流体連通することを可能にするための、前記一体的なアクセスポートと流れ連通する一体的な穿刺部材と
を備えるデバイス。 - 請求項8ないし請求項10のいずれか一項に記載のデバイスであって、
前記汎用薬瓶アダプタは、事前に取り付けられた初期の無傷の薬瓶に入れ子式に固定されることができ、
前記頂壁は、前記事前に取り付けられた初期の無傷の薬瓶の前記最上部薬瓶面の上に位置する、軸線方向に向けられた管状のステムを備え、
前記液剤移送デバイスは、さらに、前記ステムに配置された穿刺先端を有する分離した液体移送部材であって、前記薬瓶内部との流体連通を可能にするために、前記液体移送部材を前記薬瓶の方へ下方に押したときに前記薬瓶ストッパを穿刺するための液体移送部材を備える
デバイス。 - 輸液を収容するとともに注入ポートを有する輸液バッグとともに使用するための液剤移送デバイスであって、
前記注入ポートは、露出したプラグ表面を有する自己シールプラグを備える注入ポート先端で終端し、
前記注入ポート先端は、後端の注入ポートリムを有し、
前記液剤移送デバイスは、長手方向のハウジング軸線を有する、端部が開口したハウジングを備え、さらに、汎用注入ポートコネクタを備え、
前記汎用注入ポートコネクタは、前記長手方向のハウジング軸線と同一方向の長手方向のコネクタ軸線と、前記長手方向のコネクタ軸線と交差する水平面を形成する閉じた支持リングと、を有し、
前記支持リングは、該支持リングに弾性的に撓むように取り付けられた多数の湾曲したコネクタ部材を有し、
コネクタ部材自由端が、前記端部が開口したハウジングの方向から前記支持リングの下に位置するコネクタ開口に向かって収束し、その結果、前記汎用注入ポートコネクタは、全体的に椀状形状をなし、
前記注入ポート先端を、前記コネクタ開口を通って前記端部が開口したハウジングの中に摺動的に強制的に挿入した際に、前記注入ポート先端が前記多数のコネクタ部材を、前記コネクタ軸線に対して撓んでいない位置から外向きに撓ませ、前記後端の注入ポートリムの後ろでスナップ止めされ、それによって、前記摺動的に強制的に挿入する方向と反対方向に、前記端部が開口したハウジングから前記注入ポート先端を外向きに摺動させて引き抜くことが妨げられるように構成された
液剤移送デバイス。
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IL221634A IL221634A0 (en) | 2012-08-26 | 2012-08-26 | Universal drug vial adapter |
IL221634 | 2012-08-26 | ||
US201261731574P | 2012-11-30 | 2012-11-30 | |
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PCT/IL2013/050706 WO2014033706A2 (en) | 2012-08-26 | 2013-08-20 | Liquid drug transfer devices |
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JP2015065985A (ja) * | 2013-09-26 | 2015-04-13 | テルモ株式会社 | バイアルアダプタ |
JP2020500582A (ja) * | 2016-12-06 | 2020-01-16 | ウエスト・ファーマ.サービシーズ・イスラエル,リミテッド | 完全なままの個別注射バイアル解放ツールと共に使用するための液剤移動装置 |
JP2020156828A (ja) * | 2019-03-27 | 2020-10-01 | 株式会社ジェイ・エム・エス | アダプタ |
WO2020196511A1 (ja) * | 2019-03-27 | 2020-10-01 | 株式会社ジェイ・エム・エス | アダプタ |
JP7223265B2 (ja) | 2019-03-27 | 2023-02-16 | 株式会社ジェイ・エム・エス | アダプタ |
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WO2014033706A3 (en) | 2014-06-19 |
IL268585B2 (en) | 2023-12-01 |
EP3167866B1 (en) | 2017-11-22 |
CN105769561B (zh) | 2018-08-14 |
US9839580B2 (en) | 2017-12-12 |
EP2887919B1 (en) | 2016-12-28 |
JP5996758B2 (ja) | 2016-09-21 |
CN105769561A (zh) | 2016-07-20 |
IL237241A0 (en) | 2015-04-30 |
US20170312175A1 (en) | 2017-11-02 |
IL221634A0 (en) | 2012-12-31 |
US20150209230A1 (en) | 2015-07-30 |
WO2014033706A2 (en) | 2014-03-06 |
IL268585B1 (en) | 2023-08-01 |
DK3167866T3 (en) | 2018-02-26 |
JP2016028752A (ja) | 2016-03-03 |
JP5837263B2 (ja) | 2015-12-24 |
EP3167866A1 (en) | 2017-05-17 |
CN104755059B (zh) | 2016-06-08 |
CN104755059A (zh) | 2015-07-01 |
IL237241B (en) | 2019-08-29 |
DK2887919T3 (en) | 2017-03-27 |
US10299990B2 (en) | 2019-05-28 |
EP2887919A2 (en) | 2015-07-01 |
IL268585A (en) | 2019-09-26 |
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