JP2014534812A5 - - Google Patents
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- JP2014534812A5 JP2014534812A5 JP2014536328A JP2014536328A JP2014534812A5 JP 2014534812 A5 JP2014534812 A5 JP 2014534812A5 JP 2014536328 A JP2014536328 A JP 2014536328A JP 2014536328 A JP2014536328 A JP 2014536328A JP 2014534812 A5 JP2014534812 A5 JP 2014534812A5
- Authority
- JP
- Japan
- Prior art keywords
- target polynucleotide
- pore
- helicase
- characterizing
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002157 polynucleotide Substances 0.000 claims 26
- 102000040430 polynucleotide Human genes 0.000 claims 26
- 108091033319 polynucleotide Proteins 0.000 claims 26
- 239000011148 porous material Substances 0.000 claims 23
- 108060004795 Methyltransferase Proteins 0.000 claims 18
- 238000000034 method Methods 0.000 claims 13
- 102100022536 Helicase POLQ-like Human genes 0.000 claims 10
- 101000899334 Homo sapiens Helicase POLQ-like Proteins 0.000 claims 10
- 238000005259 measurement Methods 0.000 claims 5
- 108010013381 Porins Proteins 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 102000007739 porin activity proteins Human genes 0.000 claims 4
- 230000000694 effects Effects 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 108091005703 transmembrane proteins Proteins 0.000 claims 3
- 102000035160 transmembrane proteins Human genes 0.000 claims 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 2
- 108010006464 Hemolysin Proteins Proteins 0.000 claims 2
- 108010014603 Leukocidins Proteins 0.000 claims 2
- 241000187480 Mycobacterium smegmatis Species 0.000 claims 2
- 101710203388 Outer membrane porin G Proteins 0.000 claims 2
- 238000012512 characterization method Methods 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000003228 hemolysin Substances 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 102000004895 Lipoproteins Human genes 0.000 claims 1
- 108090001030 Lipoproteins Proteins 0.000 claims 1
- 241000588653 Neisseria Species 0.000 claims 1
- 108700006385 OmpF Proteins 0.000 claims 1
- 108010073429 Type V Secretion Systems Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 230000005669 field effect Effects 0.000 claims 1
- 238000002847 impedance measurement Methods 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- 230000011987 methylation Effects 0.000 claims 1
- 238000007069 methylation reaction Methods 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 108010014203 outer membrane phospholipase A Proteins 0.000 claims 1
- 230000003647 oxidation Effects 0.000 claims 1
- 238000007254 oxidation reaction Methods 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 125000006850 spacer group Chemical group 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161549998P | 2011-10-21 | 2011-10-21 | |
| US61/549,998 | 2011-10-21 | ||
| US201261599244P | 2012-02-15 | 2012-02-15 | |
| US61/599,244 | 2012-02-15 | ||
| PCT/GB2012/052579 WO2013057495A2 (en) | 2011-10-21 | 2012-10-18 | Enzyme method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534812A JP2014534812A (ja) | 2014-12-25 |
| JP2014534812A5 true JP2014534812A5 (enExample) | 2015-12-10 |
| JP6226869B2 JP6226869B2 (ja) | 2017-11-08 |
Family
ID=47073477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014536328A Active JP6226869B2 (ja) | 2011-10-21 | 2012-10-18 | 酵素法 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US9758823B2 (enExample) |
| EP (2) | EP2987870B1 (enExample) |
| JP (1) | JP6226869B2 (enExample) |
| KR (1) | KR20140090633A (enExample) |
| CN (1) | CN104039979B (enExample) |
| AU (1) | AU2012324639B2 (enExample) |
| BR (1) | BR112014009579B1 (enExample) |
| CA (1) | CA2852812A1 (enExample) |
| WO (1) | WO2013057495A2 (enExample) |
Families Citing this family (142)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008102121A1 (en) | 2007-02-20 | 2008-08-28 | Oxford Nanopore Technologies Limited | Formation of lipid bilayers |
| GB0724736D0 (en) | 2007-12-19 | 2008-01-30 | Oxford Nanolabs Ltd | Formation of layers of amphiphilic molecules |
| CN104710519B (zh) | 2008-09-22 | 2021-05-28 | 华盛顿大学 | Msp纳米微孔和相关方法 |
| AU2010209528B2 (en) | 2009-01-30 | 2015-10-01 | Oxford Nanopore Technologies Limited | Adaptors for nucleic acid constructs in transmembrane sequencing |
| BR112013030529B1 (pt) | 2011-05-27 | 2023-03-07 | Oxford Nanopore Technologies Plc | Método para determinar a presença, ausência ou características de um analito, método e aparelho para sequenciamento de um analito que é um polinucleotídeo alvo, e, kit |
| JP6298404B2 (ja) | 2011-07-25 | 2018-03-20 | オックスフォード ナノポール テクノロジーズ リミテッド | 膜貫通ポアを用いる二重鎖ポリヌクレオチド配列決定のためのヘアピンループ方法 |
| US20160162634A1 (en) | 2011-09-23 | 2016-06-09 | Oxford Nanopore Technologies Limited | Analysis of a polymer comprising polymer units |
| CN104039979B (zh) | 2011-10-21 | 2016-08-24 | 牛津纳米孔技术公司 | 使用孔和Hel308解旋酶表征目标多核苷酸的酶方法 |
| CN104136631B (zh) | 2011-12-29 | 2017-03-01 | 牛津纳米孔技术公司 | 使用xpd解旋酶表征多核苷酸的方法 |
| BR112014016112B8 (pt) | 2011-12-29 | 2022-12-27 | Oxford Nanopore Tech Ltd | Método e aparelho para caracterizar um polinucleotídeo alvo, kit, e, uso de uma helicase |
| GB201202519D0 (en) | 2012-02-13 | 2012-03-28 | Oxford Nanopore Tech Ltd | Apparatus for supporting an array of layers of amphiphilic molecules and method of forming an array of layers of amphiphilic molecules |
| WO2013121201A1 (en) | 2012-02-15 | 2013-08-22 | Oxford Nanopore Technologies Limited | Aptamer method |
| CN104321441B (zh) | 2012-02-16 | 2016-10-19 | 牛津楠路珀尔科技有限公司 | 聚合物的测量的分析 |
| KR102083695B1 (ko) | 2012-04-10 | 2020-03-02 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 돌연변이체 리세닌 기공 |
| US10808231B2 (en) | 2012-07-19 | 2020-10-20 | Oxford Nanopore Technologies Limited | Modified helicases |
| JP6429773B2 (ja) | 2012-07-19 | 2018-11-28 | オックスフォード ナノポール テクノロジーズ リミテッド | 酵素構築物 |
| EP2875154B1 (en) | 2012-07-19 | 2017-08-23 | Oxford Nanopore Technologies Limited | SSB method for characterising a nucleic acid |
| US9551023B2 (en) | 2012-09-14 | 2017-01-24 | Oxford Nanopore Technologies Ltd. | Sample preparation method |
| GB201313121D0 (en) | 2013-07-23 | 2013-09-04 | Oxford Nanopore Tech Ltd | Array of volumes of polar medium |
| US9995728B2 (en) | 2012-11-06 | 2018-06-12 | Oxford Nanopore Technologies Ltd. | Quadruplex method |
| GB201222928D0 (en) | 2012-12-19 | 2013-01-30 | Oxford Nanopore Tech Ltd | Analysis of a polynucleotide |
| CA2901545C (en) | 2013-03-08 | 2019-10-08 | Oxford Nanopore Technologies Limited | Use of spacer elements in a nucleic acid to control movement of a helicase |
| GB201318465D0 (en) | 2013-10-18 | 2013-12-04 | Oxford Nanopore Tech Ltd | Method |
| GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
| GB201313477D0 (en) | 2013-07-29 | 2013-09-11 | Univ Leuven Kath | Nanopore biosensors for detection of proteins and nucleic acids |
| WO2014190299A2 (en) * | 2013-05-23 | 2014-11-27 | Arizona Board Of Regents Acting For And On Behalf Of Arizona State University | Chemistry, systems and methods of translocation of a polymer through a nanopore |
| CN117965707A (zh) | 2013-10-18 | 2024-05-03 | 牛津纳米孔科技公开有限公司 | 经修饰的酶 |
| GB201406151D0 (en) | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
| JP6800749B2 (ja) | 2013-11-26 | 2020-12-23 | イルミナ インコーポレイテッド | ポリヌクレオチド配列決定のための組成物及び方法 |
| GB201406155D0 (en) * | 2014-04-04 | 2014-05-21 | Oxford Nanopore Tech Ltd | Method |
| AU2015208919B9 (en) | 2014-01-22 | 2021-04-01 | Oxford Nanopore Technologies Limited | Method for attaching one or more polynucleotide binding proteins to a target polynucleotide |
| SG10202111841TA (en) | 2014-02-19 | 2021-12-30 | Univ Washington | Nanopore-based analysis of protein characteristics |
| GB201403096D0 (en) | 2014-02-21 | 2014-04-09 | Oxford Nanopore Tech Ltd | Sample preparation method |
| EP3126515B1 (en) | 2014-04-04 | 2018-08-29 | Oxford Nanopore Technologies Limited | Method for characterising a double stranded nucleic acid using a nano-pore and anchor molecules at both ends of said nucleic acid |
| WO2015166275A1 (en) | 2014-05-02 | 2015-11-05 | Oxford Nanopore Technologies Limited | Mutant pores |
| GB201417712D0 (en) | 2014-10-07 | 2014-11-19 | Oxford Nanopore Tech Ltd | Method |
| WO2015187670A2 (en) | 2014-06-03 | 2015-12-10 | Illumina, Inc. | Compositions, systems, and methods for detecting events using tethers anchored to or adjacent to nanopores |
| GB201411285D0 (en) * | 2014-06-25 | 2014-08-06 | Prosser Joseph | Sequencer |
| JP6601852B2 (ja) * | 2014-07-31 | 2019-11-06 | イルミナ インコーポレイテッド | ハイブリッドナノポアセンサ |
| CN119899249A (zh) | 2014-09-01 | 2025-04-29 | 弗拉芒区生物技术研究所 | 突变csgg孔 |
| US10266885B2 (en) | 2014-10-07 | 2019-04-23 | Oxford Nanopore Technologies Ltd. | Mutant pores |
| GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
| KR102551897B1 (ko) | 2014-10-16 | 2023-07-06 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 폴리머의 분석 |
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| GB201418469D0 (en) | 2014-10-17 | 2014-12-03 | Oxford Nanopore Tech Ltd | Method |
| CN107109489B (zh) * | 2014-10-17 | 2021-11-30 | 牛津纳米孔技术公司 | 纳米孔rna表征方法 |
| CN107208160B (zh) | 2015-01-30 | 2023-02-17 | 哈佛学院院长及董事 | 无显微镜成像 |
| CN107533045B (zh) | 2015-02-05 | 2020-10-09 | 哈佛大学校长及研究员协会 | 包括流体通道的纳米孔感测器 |
| GB201502810D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Method |
| GB201502809D0 (en) | 2015-02-19 | 2015-04-08 | Oxford Nanopore Tech Ltd | Mutant pore |
| EP3283887B1 (en) | 2015-04-14 | 2021-07-21 | Katholieke Universiteit Leuven | Nanopores with internal protein adaptors |
| GB201508003D0 (en) | 2015-05-11 | 2015-06-24 | Oxford Nanopore Tech Ltd | Apparatus and methods for measuring an electrical current |
| GB201508669D0 (en) | 2015-05-20 | 2015-07-01 | Oxford Nanopore Tech Ltd | Methods and apparatus for forming apertures in a solid state membrane using dielectric breakdown |
| JP6595005B2 (ja) | 2015-06-03 | 2019-10-23 | イラミーナ インコーポレーテッド | ナノポアに隣接するポリメラーゼに固定されたテザーを用いるポリヌクレオチドの配列決定のための組成物、システム、および方法 |
| AU2016369071B2 (en) | 2015-12-08 | 2022-05-19 | Katholieke Universiteit Leuven Ku Leuven Research & Development | Modified nanopores, compositions comprising the same, and uses thereof |
| JP7085999B2 (ja) * | 2016-02-17 | 2022-06-17 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 分子プログラミングツール |
| CN108779170A (zh) | 2016-03-02 | 2018-11-09 | 牛津纳米孔技术公司 | 突变孔 |
| AU2017246690B2 (en) | 2016-04-06 | 2022-03-24 | Oxford Nanopore Technologies Plc | Mutant pore |
| GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| EP4063521B1 (en) | 2016-05-25 | 2024-02-21 | Oxford Nanopore Technologies PLC | Method of nanopore sequencing |
| GB201609221D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
| GB201611770D0 (en) | 2016-07-06 | 2016-08-17 | Oxford Nanopore Tech | Microfluidic device |
| EP3516079B1 (en) | 2016-09-20 | 2022-06-22 | President and Fellows of Harvard College | Molecular product authentication systems |
| GB201616590D0 (en) | 2016-09-29 | 2016-11-16 | Oxford Nanopore Technologies Limited | Method |
| GB201619930D0 (en) | 2016-11-24 | 2017-01-11 | Oxford Nanopore Tech | Apparatus and methods for controlling insertion of a membrane channel into a membrane |
| GB201620450D0 (en) | 2016-12-01 | 2017-01-18 | Oxford Nanopore Tech Ltd | Method |
| JP7116062B2 (ja) | 2017-01-10 | 2022-08-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 多重化シグナル増幅 |
| JP2020505043A (ja) | 2017-01-24 | 2020-02-20 | 四川大学 | 核酸巻き戻し機能を有する膜貫通型ナノポア並びにその構築方法及び用途 |
| AU2018218531B2 (en) | 2017-02-10 | 2021-01-28 | Oxford Nanopore Technologies Limited | Modified nanopores, compositions comprising the same, and uses thereof |
| GB201707122D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Pore |
| GB201707140D0 (en) | 2017-05-04 | 2017-06-21 | Oxford Nanopore Tech Ltd | Method |
| US11999948B2 (en) * | 2017-05-04 | 2024-06-04 | The Regents Of The University Of California | Methods of producing size-selected nucleic acid libraries and compositions and kits for practicing same |
| EP3957990A1 (en) * | 2017-06-29 | 2022-02-23 | President and Fellows of Harvard College | Deterministic stepping of polymers through a nanopore |
| CA3066715A1 (en) | 2017-06-30 | 2019-01-03 | Vib Vzw | Novel protein pores |
| GB2568895B (en) | 2017-11-29 | 2021-10-27 | Oxford Nanopore Tech Ltd | Microfluidic device |
| GB2569977A (en) | 2018-01-05 | 2019-07-10 | Oxford Nanopore Tech Ltd | Method |
| WO2019147945A1 (en) | 2018-01-26 | 2019-08-01 | President And Fellows Of Harvard College | Proximity detection methods and compositions |
| GB201801768D0 (en) | 2018-02-02 | 2018-03-21 | Oxford Nanopore Tech Ltd | Synthesis method |
| WO2019183359A1 (en) | 2018-03-22 | 2019-09-26 | President And Fellows Of Harvard College | Methods and compositions for molecular authentication |
| GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
| GB201808556D0 (en) | 2018-05-24 | 2018-07-11 | Oxford Nanopore Tech Ltd | Method |
| GB201808554D0 (en) | 2018-05-24 | 2018-07-11 | Oxford Nanopore Tech Ltd | Method |
| GB201809323D0 (en) | 2018-06-06 | 2018-07-25 | Oxford Nanopore Tech Ltd | Method |
| US20220162692A1 (en) | 2018-07-30 | 2022-05-26 | Oxford University Innovation Limited | Assemblies |
| JP2020031557A (ja) * | 2018-08-28 | 2020-03-05 | 株式会社日立ハイテクノロジーズ | 生体分子分析装置 |
| WO2020061997A1 (zh) * | 2018-09-28 | 2020-04-02 | 北京齐碳科技有限公司 | 一种解旋酶及其应用 |
| WO2020084705A1 (ja) * | 2018-10-24 | 2020-04-30 | 株式会社日立ハイテク | 生体ポリマ分析デバイス及びそれを用いた分析装置、並びに分析方法 |
| EP3650558A1 (en) * | 2018-11-07 | 2020-05-13 | Siemens Healthcare GmbH | Liquid sample workflow for nanopore sequencing |
| GB201821155D0 (en) | 2018-12-21 | 2019-02-06 | Oxford Nanopore Tech Ltd | Method |
| CN113574381B (zh) | 2019-03-12 | 2025-08-26 | 牛津纳米孔科技公开有限公司 | 纳米孔感测装置、组件和操作方法 |
| GB201907244D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| GB201907246D0 (en) | 2019-05-22 | 2019-07-03 | Oxford Nanopore Tech Ltd | Method |
| US11926819B2 (en) | 2019-05-28 | 2024-03-12 | The Regents Of The University Of California | Methods of adding polymers to ribonucleic acids |
| WO2021056599A1 (zh) | 2019-09-29 | 2021-04-01 | 北京齐碳科技有限公司 | 一种Mnep单体变体及其应用 |
| GB201917060D0 (en) | 2019-11-22 | 2020-01-08 | Oxford Nanopore Tech Ltd | Method |
| KR20220110213A (ko) | 2019-12-02 | 2022-08-05 | 옥스포드 나노포어 테크놀로지즈 피엘씨 | 나노포어를 사용하여 표적 폴리펩티드를 특징분석하는 방법 |
| GB201917742D0 (en) | 2019-12-04 | 2020-01-15 | Oxford Nanopore Tech Ltd | Method |
| WO2021124468A1 (ja) * | 2019-12-18 | 2021-06-24 | 株式会社日立ハイテク | 分子複合体、および生体ポリマ分析方法 |
| NL2024579B1 (en) * | 2019-12-24 | 2021-09-06 | Univ Delft Tech | Protein and peptide fingerprinting and sequencing by nanopore translocation of peptide-oligonucleotide complexes |
| GB202004944D0 (en) | 2020-04-03 | 2020-05-20 | King S College London | Method |
| JP7706479B2 (ja) | 2020-06-10 | 2025-07-11 | エフ． ホフマン－ラ ロシュ アーゲー | 膜における自己制限性プロテイン細孔挿入のためのファラデーシステム及び方法 |
| WO2021255475A1 (en) | 2020-06-18 | 2021-12-23 | Oxford Nanopore Technologies Limited | A method of selectively characterising a polynucleotide using a detector |
| WO2021255476A2 (en) | 2020-06-18 | 2021-12-23 | Oxford Nanopore Technologies Limited | Method |
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| CN113930406B (zh) | 2021-12-17 | 2022-04-08 | 北京齐碳科技有限公司 | 一种Pif1-like解旋酶及其应用 |
| CN114599666B (zh) | 2020-06-19 | 2024-08-06 | 北京齐碳科技有限公司 | 一种Pif1-like解旋酶及其应用 |
| CN115989410A (zh) | 2020-07-17 | 2023-04-18 | 牛津纳米孔科技公开有限公司 | 纳米孔感测装置 |
| US20230266268A1 (en) | 2020-07-22 | 2023-08-24 | Oxford Nanopore Technologies Inc. | Solid state nanopore formation |
| GB202015993D0 (en) | 2020-10-08 | 2020-11-25 | Oxford Nanopore Tech Ltd | Method |
| CN116601297A (zh) * | 2020-12-14 | 2023-08-15 | 北京齐碳科技有限公司 | 一种经修饰的解旋酶及其应用 |
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| GB202107192D0 (en) | 2021-05-19 | 2021-06-30 | Oxford Nanopore Tech Ltd | Method |
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| GB202107354D0 (en) | 2021-05-24 | 2021-07-07 | Oxford Nanopore Tech Ltd | Method |
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| GB202118908D0 (en) | 2021-12-23 | 2022-02-09 | Oxford Nanopore Tech Ltd | Method |
| GB202205617D0 (en) | 2022-04-14 | 2022-06-01 | Oxford Nanopore Tech Plc | Novel modified protein pores and enzymes |
| US20240026427A1 (en) | 2022-05-06 | 2024-01-25 | 10X Genomics, Inc. | Methods and compositions for in situ analysis of v(d)j sequences |
| WO2023222657A1 (en) | 2022-05-17 | 2023-11-23 | Oxford Nanopore Technologies Plc | Method and adaptors |
| EP4534691A1 (en) * | 2022-05-27 | 2025-04-09 | BGI Shenzhen | Method for maintaining nanopore sequencing speed |
| GB202211602D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| GB202211607D0 (en) | 2022-08-09 | 2022-09-21 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| JP2025526705A (ja) | 2022-08-09 | 2025-08-15 | オックスフォード ナノポール テクノロジーズ ピーエルシー | 新規な細孔モノマー及び細孔 |
| CN120303290A (zh) | 2022-10-28 | 2025-07-11 | 牛津纳米孔科技公开有限公司 | 孔单体和孔 |
| GB202216162D0 (en) | 2022-10-31 | 2022-12-14 | Oxford Nanopore Tech Plc | Method |
| GB202216905D0 (en) | 2022-11-11 | 2022-12-28 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| EP4636094A1 (en) * | 2022-12-16 | 2025-10-22 | BGI Shenzhen | Nanopore sequencing method and kit |
| GB202304324D0 (en) | 2023-03-24 | 2023-05-10 | Oxford Nanopore Tech Plc | Method and kits |
| GB202305524D0 (en) | 2023-04-14 | 2023-05-31 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
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- 2012-10-18 WO PCT/GB2012/052579 patent/WO2013057495A2/en not_active Ceased
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