|
DE1001992C2
(de)
|
1954-05-10 |
1957-07-11 |
Hoechst Ag |
Verfahren zur Herstellung von 3, 5-Di-(2'-anthrachinonyl)-4-phenyl-1, 2, 4-triazolen
|
|
US2898343A
(en)
|
1957-11-18 |
1959-08-04 |
American Cyanamid Co |
Anthraquinone triazoles
|
|
GB928919A
(en)
|
1960-08-16 |
1963-06-19 |
Bellon Labor Sa Roger |
Triazole derivatives and a process for their preparation
|
|
US3898272A
(en)
|
1966-05-06 |
1975-08-05 |
Bayer Ag |
Thionosalicylic acid anilides
|
|
DE1805156B2
(de)
|
1968-10-25 |
1976-01-29 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur herstellung von 2- acyloxythionobenzamiden
|
|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
US4178253A
(en)
|
1977-04-05 |
1979-12-11 |
Ciba-Geigy Corporation |
Corrosion inhibited lubricant compositions
|
|
US4269846A
(en)
|
1979-10-29 |
1981-05-26 |
Usv Pharmaceutical Corporation |
Heterocyclic compounds useful as anti-allergy agents
|
|
JPS5770820A
(en)
|
1980-10-20 |
1982-05-01 |
Haruo Ogura |
Immunoregulating agent
|
|
JPS5910574A
(ja)
|
1982-07-07 |
1984-01-20 |
Fujisawa Pharmaceut Co Ltd |
トリアゾ−ル誘導体およびその製造法
|
|
FR2546887B1
(fr)
|
1983-05-30 |
1985-08-30 |
Paris 7 Universite |
Procede de preparation de dihydro-2,4 triazol-1,2,4 thiones-3 disubstituees en positions 4 et 5 et nouveaux composes pouvant etre prepares par ce procede
|
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
|
US4624995A
(en)
|
1985-04-09 |
1986-11-25 |
Minnesota Mining And Manufacturing Company |
Triazolinethione-containing polymer
|
|
US4740568A
(en)
|
1985-04-09 |
1988-04-26 |
Minnesota Mining And Manufacturing Company |
Triazolinethione-containing polymer
|
|
US5436252A
(en)
|
1986-12-19 |
1995-07-25 |
Merrell Dow Pharmaceuticals Inc. |
5-aryl-3H-1,2,4-triazol-3-ones and their use in the treatment of neurodegenerative disorders
|
|
US5006650A
(en)
|
1987-02-11 |
1991-04-09 |
The Upjohn Company |
Novel N-1 substituted beta-lactams as antibiotics
|
|
DE3729070A1
(de)
|
1987-09-01 |
1989-03-09 |
Bayer Ag |
Substituierte triazolinone
|
|
US5241074A
(en)
|
1988-05-09 |
1993-08-31 |
Bayer Aktiengesellschaft |
Sulphonylaminocarbonyltriazolinones
|
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
US5219722A
(en)
|
1990-09-21 |
1993-06-15 |
Konica Corporation |
Silver halide color photographic light-sensitive material
|
|
SK278998B6
(sk)
|
1991-02-01 |
1998-05-06 |
Merck Sharp & Dohme Limited |
Deriváty imidazolu, triazolu a tetrazolu, spôsob i
|
|
US5356897A
(en)
|
1991-09-09 |
1994-10-18 |
Fujisawa Pharmaceutical Co., Ltd. |
3-(heteroaryl)-pyrazololi[1,5-a]pyrimidines
|
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
|
JP3309982B2
(ja)
|
1992-03-13 |
2002-07-29 |
メルク シヤープ エンド ドーム リミテツド |
イミダゾール,トリアゾールおよびテトラゾール誘導体
|
|
TW218017B
(enExample)
|
1992-04-28 |
1993-12-21 |
Takeda Pharm Industry Co Ltd |
|
|
DE4222771A1
(de)
|
1992-07-10 |
1994-01-13 |
Bayer Ag |
Heterocyclyltriazolinone
|
|
DE4234801A1
(de)
|
1992-10-15 |
1994-04-21 |
Bayer Ag |
Sulfonylaminocarbonyltriazolinone
|
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
|
DE4303376A1
(de)
|
1993-02-05 |
1994-08-11 |
Bayer Ag |
Substituierte Triazolinone
|
|
DE4303676A1
(de)
|
1993-02-09 |
1994-08-11 |
Bayer Ag |
1-Aryltriazolin(thi)one
|
|
US5529925A
(en)
|
1993-12-03 |
1996-06-25 |
St. Jude Children's Research Hospital |
Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma
|
|
DE4411913A1
(de)
|
1994-04-07 |
1995-10-12 |
Bayer Ag |
Substituierte Sulfonylaminocarbonyltriazolinone
|
|
US5538988A
(en)
|
1994-04-26 |
1996-07-23 |
Martinez; Gregory R. |
Benzocycloalkylazolethione derivatives
|
|
US5489598A
(en)
|
1994-06-08 |
1996-02-06 |
Warner-Lambert Company |
Cytoprotection utilizing aryltriazol-3-thiones
|
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
|
JP3372365B2
(ja)
|
1994-08-19 |
2003-02-04 |
富士写真フイルム株式会社 |
ハロゲン化銀写真感光材料およびそれを用いた画像形成方法
|
|
US5525625A
(en)
|
1995-01-24 |
1996-06-11 |
Warner-Lambert Company |
2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders
|
|
DE19502579A1
(de)
|
1995-01-27 |
1996-08-01 |
Bayer Ag |
Sulfonylamino(thio)carbonyl-triazolin(thi)one
|
|
US6080772A
(en)
|
1995-06-07 |
2000-06-27 |
Sugen, Inc. |
Thiazole compounds and methods of modulating signal transduction
|
|
DE19521162A1
(de)
|
1995-06-09 |
1996-12-12 |
Bayer Ag |
N-Aryl-1,2,4-triazolin-5-one
|
|
DE19525162A1
(de)
|
1995-07-11 |
1997-01-16 |
Bayer Ag |
Sulfonylamino(thio)carbonylverbindungen
|
|
EP0839144B1
(en)
|
1995-07-13 |
2001-09-19 |
Knoll GmbH |
Piperazine derivatives as therapeutic agents
|
|
DE19540737A1
(de)
|
1995-11-02 |
1997-05-07 |
Bayer Ag |
Substituierte Sulfonylamino(thio)carbonylverbindungen
|
|
DE19609059A1
(de)
|
1996-03-08 |
1997-09-11 |
Bayer Ag |
Substituierte Arylsulfonylamino(thio)carbonyl-triazolin(thi)one
|
|
ZA974703B
(en)
|
1996-05-30 |
1997-12-30 |
Bayer Ag |
Substituted sulfonylamino(thio)carbonyl compounds.
|
|
TW467902B
(en)
|
1996-07-31 |
2001-12-11 |
Bristol Myers Squibb Co |
Diphenyl heterocycles as potassium channel modulators
|
|
DE19632945A1
(de)
|
1996-08-16 |
1998-02-19 |
Bayer Ag |
Substituierte Sulfonylamino(thio)carbonylverbindungen
|
|
EP0938487A2
(en)
|
1996-11-12 |
1999-09-01 |
Sepracor, Inc. |
2$i(R),4$i(S),$i(R),$i(S)- AND 2$i(S),4$i(R),$i(R),$i(S)-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES
|
|
US6458373B1
(en)
|
1997-01-07 |
2002-10-01 |
Sonus Pharmaceuticals, Inc. |
Emulsion vehicle for poorly soluble drugs
|
|
US5968921A
(en)
|
1997-10-24 |
1999-10-19 |
Orgegon Health Sciences University |
Compositions and methods for promoting nerve regeneration
|
|
JP3788676B2
(ja)
|
1997-11-11 |
2006-06-21 |
富士写真フイルム株式会社 |
有機エレクトロルミネツセンス素子材料およびそれを使用した有機エレクトロルミネツセンス素子
|
|
AR017200A1
(es)
|
1997-12-23 |
2001-08-22 |
Astrazeneca Ab |
Compuestos inhibidores de la proteina cinasa c, sales farmaceuticamente aceptables de los mismos, formulaciones farmaceuitcas que los comprenden, usode las mismas y proceso para la sintesis de dichos compuestos
|
|
EP1062208A1
(de)
|
1998-03-09 |
2000-12-27 |
Basf Aktiengesellschaft |
Hetarylsubstituierte benzylphenylether, verfahren zu ihrer herstellung und ihre verwendung zur bekämpfung von schadpilzen und tierischen schädlingen
|
|
US6747055B1
(en)
|
1998-07-17 |
2004-06-08 |
The United States Of America As Represented By The Department Of Health And Human Services |
Water-soluble drugs and methods for their production
|
|
US6858598B1
(en)
|
1998-12-23 |
2005-02-22 |
G. D. Searle & Co. |
Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
|
|
JP2000284412A
(ja)
|
1999-03-30 |
2000-10-13 |
Fuji Photo Film Co Ltd |
熱現像写真材料
|
|
US6492406B1
(en)
|
1999-05-21 |
2002-12-10 |
Astrazeneca Ab |
Pharmaceutically active compounds
|
|
SE9902387D0
(sv)
|
1999-06-22 |
1999-06-22 |
Astra Ab |
New pharmaceutically active compounds
|
|
US20040110684A1
(en)
|
1999-08-02 |
2004-06-10 |
Universite Catholique De Louvain |
Novel pharmaceutical compositions for modulating angiogenesis
|
|
US6921763B2
(en)
|
1999-09-17 |
2005-07-26 |
Abbott Laboratories |
Pyrazolopyrimidines as therapeutic agents
|
|
JP2003510359A
(ja)
|
1999-10-01 |
2003-03-18 |
スミスクライン・ビーチャム・コーポレイション |
化合物および方法
|
|
CA2429196A1
(en)
|
2000-03-24 |
2001-10-04 |
Duke University |
Characterization of grp94-ligand interactions and purification, screening, and therapeutic methods relating thereto
|
|
US20030216385A1
(en)
|
2000-05-19 |
2003-11-20 |
Takahiko Tobe |
Triazole derivatives
|
|
WO2002002123A1
(en)
|
2000-06-29 |
2002-01-10 |
Trustees Of Boston University |
Use of geldanamycin and related compounds for prophylaxis or treatment of fibrogenic disorders
|
|
CA2416685C
(en)
|
2000-07-19 |
2008-10-07 |
Warner-Lambert Company |
Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids
|
|
ATE526019T1
(de)
|
2000-07-28 |
2011-10-15 |
Sloan Kettering Inst Cancer |
Verfahren zur behandlung von zellproliferationen störungen und virusinfektionen
|
|
AU2877202A
(en)
|
2000-11-02 |
2002-05-15 |
Sloan Kettering Inst Cancer |
Methods for enhancing the efficacy of cytotoxic agents through the use of hsp90 inhibitors
|
|
WO2002066447A1
(en)
|
2001-02-21 |
2002-08-29 |
Ono Pharmaceutical Co., Ltd. |
4h-1,2,4-triazole-3(2h)-thione deratives as sphingomyelinase inhibitors
|
|
WO2002069900A2
(en)
|
2001-03-01 |
2002-09-12 |
Conforma Therapeutics Corp. |
Methods for treating genetically-defined proliferative disorders with hsp90 inhibitors
|
|
ES2251582T3
(es)
|
2001-03-09 |
2006-05-01 |
Pfizer Products Inc. |
Compuestos antiinflamatorios de bencimidazol.
|
|
US20040235813A1
(en)
|
2001-05-03 |
2004-11-25 |
Erich Wanker |
Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation
|
|
WO2002094196A2
(en)
|
2001-05-23 |
2002-11-28 |
Sloan Kettering Institute For Cancer Research |
Method of treatment for cancers associated with elevated
|
|
SK287857B6
(sk)
|
2001-05-24 |
2012-01-04 |
Eli Lilly And Company |
Novel pyrrole derivatives as pharmaceutical agents
|
|
JP4102124B2
(ja)
|
2001-08-01 |
2008-06-18 |
富士フイルム株式会社 |
ハロゲン化銀乳剤およびハロゲン化銀写真感光材料
|
|
EP1420747A4
(en)
|
2001-08-06 |
2010-06-02 |
Kosan Biosciences Inc |
ANSAMYCIN BENZOQUINONE
|
|
CA2460345A1
(en)
|
2001-09-13 |
2003-03-20 |
Synta Pharmaceuticals Corp. |
2-aroylimidazole compounds for treating cancer
|
|
US7473695B2
(en)
|
2001-10-22 |
2009-01-06 |
Mitsubishi Tanabe Pharma Corporation |
4-imidazolin-2-one compounds
|
|
RU2367655C2
(ru)
|
2001-11-28 |
2009-09-20 |
Сосьете Де Консей Де Решерш Э Д`Аппликасьон Сьентифик (С.К.Р.А.С.) |
5-сульфанил-4н-1,2,4-триазольные производные и их применение в качестве лекарственного препарата
|
|
AU2002365899B2
(en)
|
2001-12-04 |
2007-09-13 |
Onyx Pharmaceuticals, Inc. |
RAF-MEK-ERK pathway inhibitors to treat cancer
|
|
WO2003050295A2
(en)
|
2001-12-12 |
2003-06-19 |
Conforma Therapeutics Corporation |
Assays and implements for determining and modulating hsp90 binding activity
|
|
JP4399265B2
(ja)
|
2001-12-21 |
2010-01-13 |
ヴァーナリス(ケンブリッジ)リミテッド |
3,4−ジアリールピラゾール、および癌の治療におけるそれらの使用
|
|
DE60330227D1
(de)
|
2002-03-13 |
2010-01-07 |
Array Biopharma Inc |
N3-alkylierte benzimidazol-derivate als mek-hemmer
|
|
GB0207362D0
(en)
|
2002-03-28 |
2002-05-08 |
Univ Liverpool |
Chemotherapy
|
|
GB0208516D0
(en)
|
2002-04-15 |
2002-05-22 |
Univ Liverpool |
Chemotherapy
|
|
AU2003274576A1
(en)
|
2002-11-15 |
2004-06-15 |
Warner-Lambert Company Llc |
Combination chemotherapy comprising a mek inhibitor and capecitabine for treating cancer
|
|
GB0228417D0
(en)
|
2002-12-05 |
2003-01-08 |
Cancer Rec Tech Ltd |
Pyrazole compounds
|
|
GB0229618D0
(en)
|
2002-12-19 |
2003-01-22 |
Cancer Rec Tech Ltd |
Pyrazole compounds
|
|
CA2515726C
(en)
|
2003-02-11 |
2012-07-10 |
Vernalis (Cambridge) Limited |
Isoxazole compounds
|
|
EP1457499A1
(en)
|
2003-03-12 |
2004-09-15 |
Tufts University School Of Medicine |
Inhibitors of extracellular Hsp90
|
|
JP2006514994A
(ja)
|
2003-03-13 |
2006-05-18 |
コンフォーマ・セラピューティクス・コーポレイション |
長鎖および中鎖トリグリセリドを有する医薬製剤
|
|
JP2006522745A
(ja)
|
2003-04-11 |
2006-10-05 |
ノボ ノルディスク アクティーゼルスカブ |
置換1,2,4−トリアゾールの薬学的使用
|
|
WO2004089415A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST
|
|
WO2004089416A2
(en)
|
2003-04-11 |
2004-10-21 |
Novo Nordisk A/S |
Combination of an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent
|
|
US7378233B2
(en)
|
2003-04-12 |
2008-05-27 |
The Johns Hopkins University |
BRAF mutation T1796A in thyroid cancers
|
|
DE10318020A1
(de)
|
2003-04-19 |
2004-11-11 |
Repower Systems Ag |
Gitterturm für eine Windkraftanlage
|
|
SE0301232D0
(sv)
|
2003-04-25 |
2003-04-25 |
Astrazeneca Ab |
Novel use
|
|
GB0309637D0
(en)
|
2003-04-28 |
2003-06-04 |
Cancer Rec Tech Ltd |
Pyrazole compounds
|
|
US20050020534A1
(en)
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites
|
|
US20050054625A1
(en)
|
2003-05-30 |
2005-03-10 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with nuclear export inhibitors
|
|
US20050020557A1
(en)
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
|
|
US7691838B2
(en)
|
2003-05-30 |
2010-04-06 |
Kosan Biosciences Incorporated |
Method for treating diseases using HSP90-inhibiting agents in combination with antimitotics
|
|
US20050026893A1
(en)
|
2003-05-30 |
2005-02-03 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with immunosuppressants
|
|
US20050054589A1
(en)
|
2003-05-30 |
2005-03-10 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with antibiotics
|
|
US20050020556A1
(en)
|
2003-05-30 |
2005-01-27 |
Kosan Biosciences, Inc. |
Method for treating diseases using HSP90-inhibiting agents in combination with platinum coordination complexes
|
|
US20050019918A1
(en)
|
2003-06-03 |
2005-01-27 |
Hidetoshi Sumimoto |
Treatment of cancer by inhibiting BRAF expression
|
|
AU2004248160B2
(en)
|
2003-06-12 |
2010-05-27 |
Merck Sharp & Dohme Corp. |
Prodrugs of mitotic kinesin inhibitors
|
|
GB0315111D0
(en)
|
2003-06-27 |
2003-07-30 |
Cancer Rec Tech Ltd |
Substituted 5-membered ring compounds and their use
|
|
CA2536470A1
(en)
|
2003-08-15 |
2005-02-24 |
Vertex Pharmaceuticals Incorporated |
Pyrrole compositions useful as inhibitors of c-met
|
|
JP2005084612A
(ja)
|
2003-09-11 |
2005-03-31 |
Fuji Photo Film Co Ltd |
ハロゲン化銀乳剤、ハロゲン化銀感光材料、および熱現像感光材料
|
|
EP1682181A2
(en)
|
2003-09-23 |
2006-07-26 |
Novartis AG |
Combination of a vegf receptor inhibitor with a chemotherapeutic agent
|
|
EP1697352B1
(en)
|
2003-09-24 |
2012-06-27 |
Vertex Pharmceuticals Incorporated |
4-azole substituted imidazole compositions useful as inhibitors or c-met receptor tyrosine kinase
|
|
US20050085531A1
(en)
|
2003-10-03 |
2005-04-21 |
Hodge Carl N. |
Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
|
|
WO2005039569A1
(en)
|
2003-10-18 |
2005-05-06 |
Bayer Healthcare Ag |
5-substituted 2-(phenylmethyl) thio-4-phenyl-4h-1,2,4-triazole derivatives and related compounds as gaba-agonists for the treatment of urinary incontinence and related diseases
|
|
JP2007509968A
(ja)
|
2003-10-28 |
2007-04-19 |
ファルマシア・コーポレーション |
新形成を治療または予防するためのhsp90阻害剤およびホスホジエステラーゼ阻害剤を含む組み合わせ
|
|
WO2005044194A2
(en)
|
2003-10-28 |
2005-05-19 |
Pharmacia Corporation |
TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR
|
|
US6855705B1
(en)
|
2003-11-12 |
2005-02-15 |
Kosan Biosciences, Inc. |
11-O-methylgeldanamycin compounds
|
|
CA2558224A1
(en)
|
2004-03-08 |
2005-09-22 |
Wyeth |
Ion channel modulators
|
|
US20050288347A1
(en)
|
2004-03-26 |
2005-12-29 |
Hodge Carl N |
Certain triazole-based compounds, compositions, and uses thereof
|
|
US20050267087A1
(en)
|
2004-04-28 |
2005-12-01 |
Vassiliki Poulaki |
Inflammatory eye disease
|
|
ES2564127T5
(es)
|
2004-06-04 |
2020-03-26 |
Genentech Inc |
Mutaciones en EGFR
|
|
GB0416168D0
(en)
|
2004-07-20 |
2004-08-18 |
Vernalis Cambridge Ltd |
Pyrmidothiophene compounds
|
|
DE102004039280A1
(de)
|
2004-08-13 |
2006-02-23 |
Merck Patent Gmbh |
1,5-Diphenyl-pyrazole
|
|
WO2006036892A2
(en)
|
2004-09-24 |
2006-04-06 |
Sapphire Therapeutics, Inc. |
Use of inhibitors of 24-hydroxylase in the treatment of cancer
|
|
DE102004049078A1
(de)
|
2004-10-08 |
2006-04-13 |
Merck Patent Gmbh |
Phenylpyrazole
|
|
US8143299B2
(en)
|
2004-10-25 |
2012-03-27 |
University Of Medicine And Dentistry Of New Jersey |
Anti-mitotic anti-proliferative compounds
|
|
WO2006091246A1
(en)
|
2004-11-01 |
2006-08-31 |
University Of Southern California |
Novel compounds for treatment of cancer and disorders associated with angiogenesis function
|
|
RS52642B
(sr)
|
2004-11-18 |
2013-06-28 |
Synta Pharmaceuticals Corp. |
Jedinjenja triazola koja modulišu aktivnost hsp90
|
|
WO2006061712A2
(en)
|
2004-12-10 |
2006-06-15 |
Pfizer Inc. |
Use of mek inhibitors in treating abnormal cell growth
|
|
DE102005007304A1
(de)
|
2005-02-17 |
2006-08-24 |
Merck Patent Gmbh |
Triazolderivate
|
|
EA013521B1
(ru)
|
2005-02-25 |
2010-06-30 |
Серенекс, Инк. |
Производные тетрагидроиндазолона
|
|
EP1857446B1
(en)
|
2005-03-09 |
2013-05-01 |
Nippon Kayaku Kabushiki Kaisha |
Derivatives of 3-(2,4-dihydroxyphenyl)-1,2,4-triazole useful in the treatment of cancer
|
|
US8399464B2
(en)
|
2005-03-09 |
2013-03-19 |
Nippon Kayaku Kabushiki Kaisha |
HSP90 inhibitor
|
|
JP2008137894A
(ja)
|
2005-03-22 |
2008-06-19 |
Nippon Kayaku Co Ltd |
新規なアセチレン誘導体
|
|
CN101253160A
(zh)
|
2005-07-06 |
2008-08-27 |
西科尔公司 |
制备来曲唑的改进方法
|
|
JP5149177B2
(ja)
|
2005-07-25 |
2013-02-20 |
シンタ ファーマシューティカルズ コーポレーション |
増殖性疾患の治療のための、チューブリンポリマー化の1,2,3−トリアゾール系抑制剤
|
|
US7473784B2
(en)
|
2005-08-01 |
2009-01-06 |
Bristol-Myers Squibb Company |
Benzothiazole and azabenzothiazole compounds useful as kinase inhibitors
|
|
EP1934185A1
(en)
|
2005-08-12 |
2008-06-25 |
Synta Pharmaceuticals Corporation |
Pyrazole compounds that modulate hsp90 activity
|
|
CA2618724A1
(en)
|
2005-08-18 |
2007-02-22 |
Synta Pharmaceuticals Corp. |
Imidazole compounds that modulate hsp90 activity
|
|
JP5118039B2
(ja)
|
2005-08-18 |
2013-01-16 |
シンタ ファーマシューティカルズ コーポレーション |
Hsp90活性を調節するトリアゾール化合物
|
|
RU2008141761A
(ru)
|
2006-03-22 |
2010-04-27 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
ИНГИБИТОРЫ с-МЕТ ПРОТЕИНКИНАЗЫ
|
|
EP3266867A1
(en)
|
2006-04-14 |
2018-01-10 |
Cell Signaling Technology, Inc. |
Gene defects and mutant alk kinase in human solid tumors
|
|
WO2007132867A1
(ja)
|
2006-05-15 |
2007-11-22 |
Takeda Pharmaceutical Company Limited |
癌の予防及び治療剤
|
|
DE102006023337A1
(de)
|
2006-05-18 |
2007-11-22 |
Merck Patent Gmbh |
Triazolderivate II
|
|
AU2012200157B2
(en)
|
2006-05-25 |
2014-08-21 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders associated with protooncogene products
|
|
US8034834B2
(en)
|
2006-05-25 |
2011-10-11 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders with HSP90 inhibitors
|
|
AU2007267859B2
(en)
|
2006-05-25 |
2012-04-12 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate Hsp90 activity
|
|
EP2032545A2
(en)
|
2006-05-25 |
2009-03-11 |
Synta Pharmaceuticals Corporation |
Compounds that modulate hsp90 activity and methods for identifying same
|
|
CA2653332A1
(en)
|
2006-05-25 |
2007-12-06 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
|
EP2034996A2
(en)
|
2006-05-25 |
2009-03-18 |
Synta Pharmaceuticals Corporation |
Triazole compounds that modulate hsp90 activity
|
|
CA2653336C
(en)
|
2006-05-25 |
2014-10-28 |
Synta Pharmaceuticals Corp. |
Method for treating non-hodgkin's lymphoma
|
|
WO2007139952A2
(en)
|
2006-05-25 |
2007-12-06 |
Synta Pharmaceuticals Corp. |
Method for the preparation of triazole compounds with hsp90 modulating activity
|
|
AU2007284537B2
(en)
|
2006-08-17 |
2012-04-12 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate HSP90 activity
|
|
US20110046125A1
(en)
|
2006-10-19 |
2011-02-24 |
Synta Pharmaceuticals Corp. |
Method for treating infections
|
|
WO2008057246A2
(en)
|
2006-10-26 |
2008-05-15 |
Synta Pharmaceuticals Corp. |
Method for treating inflammatory disorders
|
|
DE102007002715A1
(de)
|
2007-01-18 |
2008-07-24 |
Merck Patent Gmbh |
Triazolderivat
|
|
NZ579403A
(en)
|
2007-02-08 |
2012-03-30 |
Synta Pharmaceuticals Corp |
Triazole compounds that are useful in the treatment of proliferative disorders, such as cancer
|
|
TW200901960A
(en)
|
2007-03-05 |
2009-01-16 |
Kyowa Hakko Kogyo Kk |
Pharmaceutical composition
|
|
WO2008112199A1
(en)
|
2007-03-12 |
2008-09-18 |
Synta Pharmaceuticals Corp. |
Method for inhibiting topoisomerase ii
|
|
ES2395114T3
(es)
|
2007-03-27 |
2013-02-08 |
Synta Pharmaceuticals Corporation |
Derivados de triazinona y de diazinona útiles como inhibidores de Hsp90
|
|
WO2008125633A2
(en)
|
2007-04-13 |
2008-10-23 |
Rikshospitalet - Radiumhospitalet Hf |
Egfr inhibitors for treatment and diagnosis of metastatic prostate cancer
|
|
US8648104B2
(en)
|
2007-05-25 |
2014-02-11 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders associated with mutations in c-Met
|
|
US8765802B2
(en)
|
2007-06-12 |
2014-07-01 |
Provid Pharmaceuticals, Inc. |
Kinase inhibitors, compositions thereof, and methods of use therewith
|
|
US20080318241A1
(en)
|
2007-06-18 |
2008-12-25 |
The Regents Of The University Of Michigan |
Methods and Systems for Detecting Antiangiogenesis
|
|
KR20100057030A
(ko)
|
2007-08-13 |
2010-05-28 |
신타 파마슈티칼스 코프. |
Hsp90의 활성을 조절하는 트라이아졸 화합물
|
|
JP2011503111A
(ja)
|
2007-11-12 |
2011-01-27 |
バイパー サイエンシズ,インコーポレイティド |
Parp阻害剤単独又は抗腫瘍剤との組み合わせによる乳がんの治療
|
|
AU2009210656A1
(en)
|
2008-02-08 |
2009-08-13 |
Poniard Pharmaceuticals, Inc. |
Use of picoplatin and cetuximab to treat colorectal cancer
|
|
AU2009215168A1
(en)
|
2008-02-12 |
2009-08-20 |
Dana-Farber Cancer Institute |
Fish assay for EML4 and ALK fusion in lung cancer
|
|
US20090232906A1
(en)
|
2008-03-14 |
2009-09-17 |
Bionumerik Pharmaceuticals, Inc. |
Treatment methods and compositions for lung cancer, adenocarcinoma, and other medical conditions
|
|
US9156836B2
(en)
|
2008-05-16 |
2015-10-13 |
Synta Pharmaceuticals Corp. |
Tricyclic triazole compounds that modulate HSP90 activity
|
|
US8450500B2
(en)
|
2008-06-04 |
2013-05-28 |
Synta Pharmaceuticals Corp. |
Pyrrole compounds that modulate HSP90 activity
|
|
WO2009158026A1
(en)
|
2008-06-27 |
2009-12-30 |
Synta Pharmaceuticals Corp. |
Hydrazonamide compounds that modulate hsp90 activity
|
|
WO2010017545A2
(en)
|
2008-08-08 |
2010-02-11 |
Synta Pharamceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
|
WO2010017479A1
(en)
|
2008-08-08 |
2010-02-11 |
Synta Pharmaceuticals Corp. |
Triazole compounds that modulate hsp90 activity
|
|
US20110319415A1
(en)
|
2008-08-18 |
2011-12-29 |
Universit+e,uml a+ee t zu K+e,uml o+ee ln |
Susceptibility to HSP90-Inhibitors
|
|
AU2009319048B2
(en)
|
2008-11-28 |
2014-01-30 |
Novartis Ag |
Pharmaceutical combination comprising a Hsp 90 inhibitor and a mTOR inhibitor
|
|
US20100209929A1
(en)
|
2009-01-14 |
2010-08-19 |
Nodality, Inc., A Delaware Corporation |
Multiple mechanisms for modulation of jak/stat activity
|
|
WO2010138377A1
(en)
|
2009-05-28 |
2010-12-02 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating cancer
|
|
NZ599445A
(en)
*
|
2009-10-19 |
2014-04-30 |
Synta Pharmaceuticals Corp |
Combination cancer therapy with hsp90 inhibitory compounds
|
|
WO2011060328A1
(en)
|
2009-11-13 |
2011-05-19 |
Infinity Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer
|
|
EP2333103A1
(en)
|
2009-12-11 |
2011-06-15 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Differential diagnosis and therapy for kinase inhibitors
|
|
EP2560641A2
(en)
|
2010-04-19 |
2013-02-27 |
Synta Pharmaceuticals Corp. |
Cancer therapy using a combination of a hsp90 inhibitory compounds and a vegf inhibitor
|
|
WO2011133520A1
(en)
|
2010-04-19 |
2011-10-27 |
Synta Pharmaceuticals Corp. |
Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor
|
|
WO2011146803A1
(en)
|
2010-05-20 |
2011-11-24 |
Synta Pharmaceuticals Corp. |
Method of treating lung adenocarcinoma with hsp90 inhibitory compounds
|
|
US20130172333A1
(en)
|
2010-05-20 |
2013-07-04 |
Synta Pharmaceuticals Corp. |
Formulation and dosing of hsp90 inhibitory compounds
|
|
US20130171105A1
(en)
|
2010-05-24 |
2013-07-04 |
Synta Pharmaceuticals Corp. |
Cancer therapy using a combination of a hsp90 inhibitory compound and a topoisomerase ii inhibitor
|
|
US20130225870A1
(en)
|
2010-08-25 |
2013-08-29 |
Synta Pharmaceuticals Corp. |
Method of synthesizing substituted 2-alkyl phenols
|
|
AU2011302344B2
(en)
|
2010-09-13 |
2015-01-15 |
Synta Pharmaceuticals Corp. |
HSP90 inhibitors for treating non-small cell lung cancers in wild-type EGFR and/or KRAS patients
|
|
CA2817564A1
(en)
|
2010-11-18 |
2012-05-24 |
Ronald K. Blackman |
Preselection of subjects for therapeutic treatment based on hypoxic status
|
|
JP2014503500A
(ja)
|
2010-11-18 |
2014-02-13 |
シンタ ファーマスーティカルズ コーポレーション |
低酸素状態に基づく酸素感受性薬剤による治療に適した被験体の事前選択
|
|
WO2012078757A2
(en)
|
2010-12-08 |
2012-06-14 |
Synta Pharmaceuticals Corp. |
Combination breast cancer therapy with hsp90 inhibitory compounds
|
|
US20130331357A1
(en)
|
2011-01-11 |
2013-12-12 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitory compounds with proteasome inhibitors
|
|
WO2012116061A1
(en)
|
2011-02-23 |
2012-08-30 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitory compounds with radiotherapy
|
|
AU2012243289A1
(en)
|
2011-02-24 |
2013-08-29 |
Synta Pharmaceuticals Corp. |
Prostate cancer therapy with Hsp90 inhibitory compounds
|
|
WO2012116247A1
(en)
|
2011-02-25 |
2012-08-30 |
Synta Pharmaceuticals Corp. |
Hsp90 inhibitory compounds in treating jak/stat signaling-mediated cancers
|
|
MY181439A
(en)
*
|
2011-02-28 |
2020-12-22 |
Sunshine Lake Pharma Co Ltd |
Substituted quinoline compounds and methods of use
|
|
WO2012155063A1
(en)
|
2011-05-11 |
2012-11-15 |
Synta Pharmaceuticals Corp. |
Treating cancer with an hsp90 inhibitory compound
|
|
EP2714039A1
(en)
|
2011-05-23 |
2014-04-09 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitory compounds with mek inhibitors
|
|
WO2012162372A1
(en)
|
2011-05-24 |
2012-11-29 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitory compounds with mtor/p13k inhibitors
|
|
WO2012162584A1
(en)
|
2011-05-26 |
2012-11-29 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitory compounds with chk inhibitors
|
|
WO2013006864A2
(en)
|
2011-07-07 |
2013-01-10 |
Synta Pharmaceuticals Corp. |
Treating cancer with hsp90 inhibitory compounds
|
|
US20140296176A1
(en)
|
2011-08-19 |
2014-10-02 |
Synta Pharmaceuticals Corp. |
Combination cancer therapy with an hsp90 inhibitor and an antimetabolite
|
|
US8628752B2
(en)
|
2011-10-28 |
2014-01-14 |
Synta Pharmaceuticals Corp. |
Methods of identifying HSP90 inhibitors with less ocular toxicity
|
|
JP2014532712A
(ja)
|
2011-11-02 |
2014-12-08 |
シンタ ファーマシューティカルズ コーポレーション |
トポイソメラーゼi阻害剤とhsp90阻害剤の組合せを使用する癌療法
|
|
WO2013067165A1
(en)
|
2011-11-02 |
2013-05-10 |
Synta Pharmaceuticals Corp. |
Combination therapy of hsp90 inhibitors with platinum-containing agents
|
|
US20150051203A1
(en)
|
2012-03-28 |
2015-02-19 |
Synta Pharmaceuticals Corp. |
Triazole derivatives as hsp90 inhibitors
|
|
JP2015515477A
(ja)
|
2012-04-04 |
2015-05-28 |
シンタ ファーマシューティカルズ コーポレーション |
Hsp90活性を調節する新規トリアゾール化合物
|
|
JP2015516439A
(ja)
|
2012-05-10 |
2015-06-11 |
シンタ ファーマシューティカルズ コーポレーション |
Hsp90阻害化合物で癌を治療すること
|
|
US10155987B2
(en)
|
2012-06-12 |
2018-12-18 |
Dana-Farber Cancer Institute, Inc. |
Methods of predicting resistance to JAK inhibitor therapy
|
|
EP2914259A1
(en)
|
2012-10-19 |
2015-09-09 |
Synta Pharmaceuticals Corp. |
Treating polycystic kidney disease with hsp90 inhibitory compounds
|
|
EP2999465A1
(en)
|
2013-05-21 |
2016-03-30 |
Synta Pharmaceuticals Corp. |
Specific cancer treatment regimens with ganetespib
|
|
WO2015109218A1
(en)
|
2014-01-17 |
2015-07-23 |
Synta Pharmaceuticals Corp. |
Targeted cancer treatment by hsp90 inhibitors ganetespib and nvp-auy922
|