BRPI0415896A - combinações compreendendo um inibidor de hsp90 e um inibidor de fosfodiesterase para tratamento ou prevenção de neoplasia - Google Patents
combinações compreendendo um inibidor de hsp90 e um inibidor de fosfodiesterase para tratamento ou prevenção de neoplasiaInfo
- Publication number
- BRPI0415896A BRPI0415896A BRPI0415896-2A BRPI0415896A BRPI0415896A BR PI0415896 A BRPI0415896 A BR PI0415896A BR PI0415896 A BRPI0415896 A BR PI0415896A BR PI0415896 A BRPI0415896 A BR PI0415896A
- Authority
- BR
- Brazil
- Prior art keywords
- inhibitor
- treating
- combinations
- preventing cancer
- phosphodiesterase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
"COMBINAçõES COMPREENDENDO UM INIBIDOR DE Hsp90 E UM INIBIDOR DE FOSFODIESTERASE PARA TRATAMENTO OU PREVENçãO DE NEOPLASIA". é providenciado um método para tratar ou prevenir neoplasia, ou um distúrbio relacionado com neoplasia num indivíduo, compreendendo o método a administração ao indivíduo de uma quantidade eficaz de uma combinação, compreendendo um inibidor de Hsp90 e um inibidor de fosfodiesterase, e, opcionalmente um inibidor de Cox-2.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51502103P | 2003-10-28 | 2003-10-28 | |
PCT/US2004/035949 WO2005041879A2 (en) | 2003-10-28 | 2004-10-28 | COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0415896A true BRPI0415896A (pt) | 2007-01-09 |
Family
ID=34549367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0415896-2A BRPI0415896A (pt) | 2003-10-28 | 2004-10-28 | combinações compreendendo um inibidor de hsp90 e um inibidor de fosfodiesterase para tratamento ou prevenção de neoplasia |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1682143A2 (pt) |
JP (1) | JP2007509968A (pt) |
BR (1) | BRPI0415896A (pt) |
CA (1) | CA2543503A1 (pt) |
MX (1) | MXPA06004657A (pt) |
WO (1) | WO2005041879A2 (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS52642B (en) | 2004-11-18 | 2013-06-28 | Synta Pharmaceuticals Corp. | TRIAZOLE COMPOUNDS MODULATING HSP90 ACTIVITY |
US8399464B2 (en) | 2005-03-09 | 2013-03-19 | Nippon Kayaku Kabushiki Kaisha | HSP90 inhibitor |
AU2006224623A1 (en) * | 2005-03-14 | 2006-09-21 | Nycomed Gmbh | Method for preventing cardiovascular diseases |
CA2700893A1 (en) * | 2007-10-12 | 2009-04-16 | Arqule, Inc. | Substituted tetrazole compounds and uses thereof |
WO2009140621A2 (en) * | 2008-05-15 | 2009-11-19 | Duke University | Compositions and methods relating to heat shock transcription factor activating compounds and targets thereof |
US9315449B2 (en) | 2008-05-15 | 2016-04-19 | Duke University | Substituted pyrazoles as heat shock transcription factor activators |
AR081810A1 (es) | 2010-04-07 | 2012-10-24 | Bayer Cropscience Ag | Piridinilpirazoles biciclicos |
EP2384752A1 (de) * | 2010-04-14 | 2011-11-09 | Universitätsklinikum Hamburg-Eppendorf | Kombinationspräparat umfassend einen Phosphodiesterasehemmer und einen COX-Inhibitor zur Behandlung von Krebs |
WO2011133520A1 (en) | 2010-04-19 | 2011-10-27 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor |
EP2773345A1 (en) | 2011-11-02 | 2014-09-10 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of hsp90 inhibitors with topoisomerase i inhibitors |
AU2012332424A1 (en) | 2011-11-02 | 2014-06-05 | Synta Pharmaceuticals Corp. | Combination therapy of Hsp90 inhibitors with platinum-containing agents |
WO2013074594A1 (en) | 2011-11-14 | 2013-05-23 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitors with braf inhibitors |
CN103102306A (zh) * | 2013-02-06 | 2013-05-15 | 河南东泰制药有限公司 | 一种塞来昔布的制备方法 |
US9663529B2 (en) | 2013-07-02 | 2017-05-30 | Bristol-Myers Squibb Company | Tricyclic pyrido-carboxamide derivatives as rock inhibitors |
TW201506024A (zh) | 2013-07-02 | 2015-02-16 | 必治妥美雅史谷比公司 | 作為有效rock抑制劑的三環甲醯胺衍生物 |
CN104069113B (zh) * | 2014-07-08 | 2016-08-31 | 山东大学齐鲁医院 | 西地那非在制备治疗抗血管瘤的药物中的应用 |
TW202039504A (zh) * | 2018-12-31 | 2020-11-01 | 美商拜歐米富士恩有限公司 | Menin-mll相互作用之不可逆抑制劑 |
CA3125353A1 (en) | 2018-12-31 | 2020-07-09 | Biomea Fusion, Llc | Inhibitors of menin-mll interaction |
CN112679470B (zh) * | 2021-01-06 | 2023-01-13 | 中国药科大学 | (e)-1-苯基4-烯基-1h-吡唑类化合物及其医药用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090834A (en) * | 1993-05-21 | 2000-07-18 | G.D. Searle & Co. | Substituted oxazoles for the treatment of inflammation |
US6492411B1 (en) * | 1993-11-30 | 2002-12-10 | G. D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation |
CA2447066A1 (en) * | 2001-05-23 | 2002-11-28 | Sloan Kettering Institute For Cancer Research | Method of treatment for cancers associated with elevated |
US20030157061A1 (en) * | 2001-12-05 | 2003-08-21 | Pharmacia Corporation | Combinations of a cyclooxygenase-2 selective inhibitor and a TNFalpha antagonist and therapeutic uses therefor |
-
2004
- 2004-10-28 CA CA002543503A patent/CA2543503A1/en not_active Abandoned
- 2004-10-28 MX MXPA06004657A patent/MXPA06004657A/es not_active Application Discontinuation
- 2004-10-28 WO PCT/US2004/035949 patent/WO2005041879A2/en not_active Application Discontinuation
- 2004-10-28 EP EP04817484A patent/EP1682143A2/en not_active Withdrawn
- 2004-10-28 JP JP2006538292A patent/JP2007509968A/ja not_active Withdrawn
- 2004-10-28 BR BRPI0415896-2A patent/BRPI0415896A/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2005041879A3 (en) | 2005-10-06 |
MXPA06004657A (es) | 2006-06-27 |
CA2543503A1 (en) | 2005-05-12 |
WO2005041879A2 (en) | 2005-05-12 |
EP1682143A2 (en) | 2006-07-26 |
JP2007509968A (ja) | 2007-04-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |