MXPA02012911A - Compuestos de rutenio (ii) para el uso en terapia del cancer. - Google Patents

Compuestos de rutenio (ii) para el uso en terapia del cancer.

Info

Publication number
MXPA02012911A
MXPA02012911A MXPA02012911A MXPA02012911A MXPA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A
Authority
MX
Mexico
Prior art keywords
cancer
compounds
ruthenium
therapy
saturated
Prior art date
Application number
MXPA02012911A
Other languages
English (en)
Inventor
Haimei Chen
Original Assignee
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Glasgow filed Critical Univ Glasgow
Publication of MXPA02012911A publication Critical patent/MXPA02012911A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Los compuestos que se pueden usar en el tratamiento y/o prevencion de cancer, los cuales tienen la formula (I); en donde R1 y R2 junto con el anillo al cual estan unidos representan un grupo carbociclico o heterociclico saturado o insaturado.
MXPA02012911A 2000-06-30 2001-06-26 Compuestos de rutenio (ii) para el uso en terapia del cancer. MXPA02012911A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0016052.3A GB0016052D0 (en) 2000-06-30 2000-06-30 Ruthenium (II) compounds
PCT/GB2001/002824 WO2002002572A1 (en) 2000-06-30 2001-06-26 Ruthenium (ii) compounds for use in the therapy of cancer

Publications (1)

Publication Number Publication Date
MXPA02012911A true MXPA02012911A (es) 2004-07-30

Family

ID=9894730

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012911A MXPA02012911A (es) 2000-06-30 2001-06-26 Compuestos de rutenio (ii) para el uso en terapia del cancer.

Country Status (14)

Country Link
US (1) US6936634B2 (es)
EP (1) EP1294732B1 (es)
JP (1) JP2004502696A (es)
AT (1) ATE273985T1 (es)
AU (1) AU2001267687A1 (es)
BR (1) BR0112122A (es)
CA (1) CA2414446A1 (es)
DE (1) DE60105028T2 (es)
DK (1) DK1294732T3 (es)
ES (1) ES2227225T3 (es)
GB (1) GB0016052D0 (es)
MX (1) MXPA02012911A (es)
PT (1) PT1294732E (es)
WO (1) WO2002002572A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003512471A (ja) * 1999-10-27 2003-04-02 ユニバーシティ コート， エディンバラ大学 窒素および配位子を含む癌治療用の半サンドイッチ状ルテニウム（ｉｉ）化合物
JP2005517648A (ja) * 2001-12-07 2005-06-16 インターミューン インコーポレイテッド 肝炎ウイルス感染症を治療するための組成物および方法
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds
ATE397003T1 (de) 2003-04-30 2008-06-15 Univ Edinburgh Ruthenium(ii)-komplexe zur behandlung von tumoren
GB0418643D0 (en) * 2004-08-20 2004-09-22 Univ Edinburgh Ruthenium (II) compounds
GB0604602D0 (en) * 2006-03-07 2006-04-19 Univ Edinburgh Ruthenium (II) compounds
GB0610062D0 (en) * 2006-05-19 2006-06-28 Univ Edinburgh Ruthenium (ll) compounds
CN101851256B (zh) * 2010-04-30 2013-01-09 广东药学院 一种以柔性碳链联接的钌(ⅱ)卟啉配合物及其制备方法和应用
CN101863925B (zh) * 2010-05-21 2012-08-29 广东药学院 一种芳基钌(ⅱ)配合物及其制备方法和应用
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980472A (en) * 1983-06-23 1990-12-25 American Cyanamid Company Method of making (3-amino-1H-pyrazol-4-yl) (aryl)methanones
WO1986000905A1 (en) * 1984-07-24 1986-02-13 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M Ruthenium compounds having a tumor inhibiting activity
WO1986000804A1 (en) 1984-07-24 1986-02-13 Byk Gulden Lomberg Chemische Fabrik Gesellschaft M Ruthenium compositions having a tumor inhibiting activity
US5225556A (en) * 1985-01-18 1993-07-06 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and for A-DNA; chiral metal complexes as Z-specific antitumor agents and as double strand cleavers
US4699978A (en) * 1985-01-18 1987-10-13 The Trustees Of Columbia University In The City Of New York Site-specific chiral ruthenium (II) and cobalt (III) antitumor agents
US4980473A (en) * 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
WO1996013510A1 (en) 1994-10-28 1996-05-09 Procept, Inc. Ruthenium complexes and their use as immunosuppressive agents
JPH11209314A (ja) 1997-09-30 1999-08-03 Takasago Internatl Corp シクロオクタジエン類の製造方法
JP3488103B2 (ja) * 1998-11-12 2004-01-19 高砂香料工業株式会社 ４−メチル−５−ヘキセン−１−アールを含有する香料組成物
GB0028025D0 (en) 2000-11-17 2001-01-03 Univ York Compounds

Also Published As

Publication number Publication date
DE60105028D1 (de) 2004-09-23
DE60105028T2 (de) 2005-08-18
BR0112122A (pt) 2003-05-13
EP1294732B1 (en) 2004-08-18
WO2002002572A1 (en) 2002-01-10
GB0016052D0 (en) 2000-08-23
US20040029852A1 (en) 2004-02-12
US6936634B2 (en) 2005-08-30
AU2001267687A1 (en) 2002-01-14
PT1294732E (pt) 2004-12-31
EP1294732A1 (en) 2003-03-26
CA2414446A1 (en) 2002-01-10
DK1294732T3 (da) 2004-12-06
JP2004502696A (ja) 2004-01-29
ES2227225T3 (es) 2005-04-01
ATE273985T1 (de) 2004-09-15

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Legal Events

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