DK1294732T3 - Ruthenium (II)-forbindelser til anvendelse i cancerterapi - Google Patents

Ruthenium (II)-forbindelser til anvendelse i cancerterapi

Info

Publication number
DK1294732T3
DK1294732T3 DK01945472T DK01945472T DK1294732T3 DK 1294732 T3 DK1294732 T3 DK 1294732T3 DK 01945472 T DK01945472 T DK 01945472T DK 01945472 T DK01945472 T DK 01945472T DK 1294732 T3 DK1294732 T3 DK 1294732T3
Authority
DK
Denmark
Prior art keywords
compounds
ruthenium
cancer therapy
sup
cancer
Prior art date
Application number
DK01945472T
Other languages
Danish (da)
English (en)
Inventor
Robert Edward Morris
Duncan Jodrell
Haimei Chen
Peter John Sadler
Original Assignee
Univ Edinburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Edinburgh filed Critical Univ Edinburgh
Application granted granted Critical
Publication of DK1294732T3 publication Critical patent/DK1294732T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0046—Ruthenium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK01945472T 2000-06-30 2001-06-26 Ruthenium (II)-forbindelser til anvendelse i cancerterapi DK1294732T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0016052.3A GB0016052D0 (en) 2000-06-30 2000-06-30 Ruthenium (II) compounds
PCT/GB2001/002824 WO2002002572A1 (en) 2000-06-30 2001-06-26 Ruthenium (ii) compounds for use in the therapy of cancer

Publications (1)

Publication Number Publication Date
DK1294732T3 true DK1294732T3 (da) 2004-12-06

Family

ID=9894730

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01945472T DK1294732T3 (da) 2000-06-30 2001-06-26 Ruthenium (II)-forbindelser til anvendelse i cancerterapi

Country Status (14)

Country Link
US (1) US6936634B2 (es)
EP (1) EP1294732B1 (es)
JP (1) JP2004502696A (es)
AT (1) ATE273985T1 (es)
AU (1) AU2001267687A1 (es)
BR (1) BR0112122A (es)
CA (1) CA2414446A1 (es)
DE (1) DE60105028T2 (es)
DK (1) DK1294732T3 (es)
ES (1) ES2227225T3 (es)
GB (1) GB0016052D0 (es)
MX (1) MXPA02012911A (es)
PT (1) PT1294732E (es)
WO (1) WO2002002572A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030790A1 (en) * 1999-10-27 2001-05-03 The University Court, The University Of Edinburgh Half-sandwich ruthenium (ii) compounds comprising nitrogen containing ligands for treatment of cancer
EP1461067A1 (en) * 2001-12-07 2004-09-29 Intermune, Inc. Compositions and method for treating hepatitis virus infection
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds
US7241913B2 (en) 2003-04-30 2007-07-10 The University Court Of The University Of Edinburgh Ruthenium compounds
GB0418643D0 (en) * 2004-08-20 2004-09-22 Univ Edinburgh Ruthenium (II) compounds
GB0604602D0 (en) * 2006-03-07 2006-04-19 Univ Edinburgh Ruthenium (II) compounds
GB0610062D0 (en) * 2006-05-19 2006-06-28 Univ Edinburgh Ruthenium (ll) compounds
CN101851256B (zh) * 2010-04-30 2013-01-09 广东药学院 一种以柔性碳链联接的钌(ⅱ)卟啉配合物及其制备方法和应用
CN101863925B (zh) * 2010-05-21 2012-08-29 广东药学院 一种芳基钌(ⅱ)配合物及其制备方法和应用
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980472A (en) * 1983-06-23 1990-12-25 American Cyanamid Company Method of making (3-amino-1H-pyrazol-4-yl) (aryl)methanones
DE3572981D1 (en) * 1984-07-24 1989-10-19 Asta Pharma Ag Ruthenium compounds having a tumor inhibiting activity
EP0188585A1 (de) 1984-07-24 1986-07-30 Byk Gulden Lomberg Chemische Fabrik GmbH Tumorhemmend wirkende rutheniumverbindungen
US4980473A (en) * 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
US5225556A (en) * 1985-01-18 1993-07-06 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and for A-DNA; chiral metal complexes as Z-specific antitumor agents and as double strand cleavers
US4699978A (en) * 1985-01-18 1987-10-13 The Trustees Of Columbia University In The City Of New York Site-specific chiral ruthenium (II) and cobalt (III) antitumor agents
AU4017695A (en) 1994-10-28 1996-05-23 Procept, Inc. Ruthenium complexes and their use as immunosuppressive agents
JPH11209314A (ja) 1997-09-30 1999-08-03 Takasago Internatl Corp シクロオクタジエン類の製造方法
JP3488103B2 (ja) * 1998-11-12 2004-01-19 高砂香料工業株式会社 ４−メチル−５−ヘキセン−１−アールを含有する香料組成物
GB0028025D0 (en) 2000-11-17 2001-01-03 Univ York Compounds

Also Published As

Publication number Publication date
BR0112122A (pt) 2003-05-13
MXPA02012911A (es) 2004-07-30
ES2227225T3 (es) 2005-04-01
CA2414446A1 (en) 2002-01-10
JP2004502696A (ja) 2004-01-29
AU2001267687A1 (en) 2002-01-14
GB0016052D0 (en) 2000-08-23
EP1294732A1 (en) 2003-03-26
DE60105028T2 (de) 2005-08-18
PT1294732E (pt) 2004-12-31
DE60105028D1 (de) 2004-09-23
US20040029852A1 (en) 2004-02-12
US6936634B2 (en) 2005-08-30
EP1294732B1 (en) 2004-08-18
ATE273985T1 (de) 2004-09-15
WO2002002572A1 (en) 2002-01-10

Similar Documents

Publication Publication Date Title
ES2133807T3 (es) Compuestos de peptidilo y su uso terapeutico como inhibidores de metaloproteasas.
IS6520A (is) Ný efnasambönd
CO5271715A1 (es) 7-aza-indolin-2-onas sustituidas en 4 y su uso como inhibidores de proteiuna quinasa
TR199901417T2 (xx) Analjezik etkisi olan yeni bile�imler.
AR035482A1 (es) Uso de un compuesto de cianoquinolina para la manufactura de un medicamento para tratar o inhibir polipos colonicos
ES2170252T3 (es) Tetrahidroimidazopiridoindoldionas como inhibidores de cgmp especifico pde.
MY138059A (en) Use of ikb-kinase inhibitors in pain therapy
SE0101387D0 (sv) Novel compounds
ATE334985T1 (de) Verbindungen, verfahren und pharmazeutische zubereitungen zur behandlung von zellschäden wie zum beispiel schäden an nerven- oder kerzgefässgewebe
PE20020521A1 (es) Compuestos heterociclicos sustituidos para tratar la resistencia a multiples drogas
PA8432901A1 (es) Compuestos de piridilpirrol
BR9805544C1 (pt) Uso de um composto.
DE60045508D1 (de) Dalda-analoge und ihre verwendung
NZ513096A (en) Compositions for treating inflammatory response
ES2101858T3 (es) Derivados de geneserina como inhibidores de colinesterasa.
DK1294732T3 (da) Ruthenium (II)-forbindelser til anvendelse i cancerterapi
ES2135769T3 (es) Derivados de isotiourea como inhibidores de no-sintasa.
SE9904674D0 (sv) Novel compounds
BR0205812A (pt) Benzimidazois úteis no tratamento da disfunção sexual
AR020563A1 (es) Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion
SE0003476D0 (sv) Compounds
GEP20053590B (en) Phenyl Heterocyclyl Ether Derivatives as Serotonin Re-Uptake Inhibitors
BR0309996A (pt) Composto, composição farmacêutica, método de tratar ou melhorar doenças ou condições proliferativas, uso de um composto, e, método de tratar ou melhorar doenças inflamatórias
SE0004827D0 (sv) Therapeutic compounds
UY26498A1 (es) Pirroles sustituidos