JP2014507443A5 - - Google Patents
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- Publication number
- JP2014507443A5 JP2014507443A5 JP2013555547A JP2013555547A JP2014507443A5 JP 2014507443 A5 JP2014507443 A5 JP 2014507443A5 JP 2013555547 A JP2013555547 A JP 2013555547A JP 2013555547 A JP2013555547 A JP 2013555547A JP 2014507443 A5 JP2014507443 A5 JP 2014507443A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- indol
- triazole
- phenyl
- mercapto
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161446099P | 2011-02-24 | 2011-02-24 | |
| US61/446,099 | 2011-02-24 | ||
| US201161491531P | 2011-05-31 | 2011-05-31 | |
| US61/491,531 | 2011-05-31 | ||
| PCT/US2012/026268 WO2012141796A2 (en) | 2011-02-24 | 2012-02-23 | Prostate cancer therapy with hsp90 inhibitory compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014507443A JP2014507443A (ja) | 2014-03-27 |
| JP2014507443A5 true JP2014507443A5 (enExample) | 2015-04-09 |
Family
ID=46614578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013555547A Pending JP2014507443A (ja) | 2011-02-24 | 2012-02-23 | Ｈｓｐ９０阻害化合物での前立腺癌治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140051665A1 (enExample) |
| EP (1) | EP2678014A2 (enExample) |
| JP (1) | JP2014507443A (enExample) |
| CN (1) | CN103391779A (enExample) |
| AU (1) | AU2012243289A1 (enExample) |
| CA (1) | CA2827739A1 (enExample) |
| WO (1) | WO2012141796A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2035396B1 (en) | 2006-05-25 | 2014-05-14 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate hsp90 activity |
| US8450500B2 (en) | 2008-06-04 | 2013-05-28 | Synta Pharmaceuticals Corp. | Pyrrole compounds that modulate HSP90 activity |
| ES2415234T3 (es) * | 2008-08-08 | 2013-07-24 | Synta Pharmaceuticals Corp. | Compuestos de triazol que modulan la actividad Hsp90 |
| WO2010017545A2 (en) | 2008-08-08 | 2010-02-11 | Synta Pharamceuticals Corp. | Triazole compounds that modulate hsp90 activity |
| RU2012136451A (ru) | 2010-01-28 | 2014-03-10 | Президент Энд Феллоуз Оф Гарвард Колледж | Композиции и способы улучшения активности протеасомы |
| EP2560640A1 (en) | 2010-04-19 | 2013-02-27 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a hsp90 inhibitory compounds and a egfr inhibitor |
| JP6208122B2 (ja) | 2011-05-12 | 2017-10-04 | プロテオステイシス セラピューティクス，インコーポレイテッド | プロテオスタシス調節因子 |
| AU2012280931A1 (en) | 2011-07-07 | 2014-02-27 | Synta Pharmaceuticals Corp. | Treating cancer with HSP90 inhibitory compounds |
| JP2014534228A (ja) | 2011-11-02 | 2014-12-18 | シンタ ファーマシューティカルズ コーポレーション | 白金含有剤とｈｓｐ９０阻害剤の組合せ療法 |
| WO2013067162A1 (en) | 2011-11-02 | 2013-05-10 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of hsp90 inhibitors with topoisomerase i inhibitors |
| CA2854188A1 (en) | 2011-11-14 | 2013-05-23 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitors with braf inhibitors |
| US9849135B2 (en) | 2013-01-25 | 2017-12-26 | President And Fellows Of Harvard College | USP14 inhibitors for treating or preventing viral infections |
| WO2015073528A1 (en) | 2013-11-12 | 2015-05-21 | Proteostasis Therapeutics, Inc. | Proteasome activity enhancing compounds |
| EP3179992B1 (en) | 2014-08-11 | 2022-05-11 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor, a pd-1 inhibitor and/or a pd-l1 inhibitor |
| US20170231986A1 (en) | 2014-08-11 | 2017-08-17 | Acerta Pharma B.V. | Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor |
| US20170224819A1 (en) | 2014-08-11 | 2017-08-10 | Acerta Pharma B.V. | Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a CDK 4/6 Inhibitor |
| US11679160B2 (en) * | 2017-09-27 | 2023-06-20 | Targimmune Therapeutics Ag | Castration resistant prostate cancer |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| KR20140006070A (ko) | 2004-11-18 | 2014-01-15 | 신타 파마슈티칼스 코프. | Ｈｓｐ90 활성을 조절하는 트리아졸 화합물 |
| CN101801983B (zh) | 2007-08-13 | 2014-01-29 | 辛塔制药公司 | 调控hsp90活性的三唑化合物 |
| WO2011149824A1 (en) * | 2010-05-24 | 2011-12-01 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a hsp90 inhibitory compound and a topoisomerase ii inhibitor |
| EP2678013A1 (en) * | 2011-02-23 | 2014-01-01 | Synta Pharmaceuticals Corp. | Combination therapy of hsp90 inhibitory compounds with radiotherapy |
-
2012
- 2012-02-23 JP JP2013555547A patent/JP2014507443A/ja active Pending
- 2012-02-23 US US14/001,465 patent/US20140051665A1/en not_active Abandoned
- 2012-02-23 EP EP12743551.9A patent/EP2678014A2/en not_active Withdrawn
- 2012-02-23 CA CA2827739A patent/CA2827739A1/en not_active Abandoned
- 2012-02-23 WO PCT/US2012/026268 patent/WO2012141796A2/en not_active Ceased
- 2012-02-23 AU AU2012243289A patent/AU2012243289A1/en not_active Abandoned
- 2012-02-23 CN CN2012800101340A patent/CN103391779A/zh active Pending
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