|
US4186745A
(en)
|
1976-07-30 |
1980-02-05 |
Kauzlarich James J |
Porous catheters
|
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US5132418A
(en)
|
1980-02-29 |
1992-07-21 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4500707A
(en)
|
1980-02-29 |
1985-02-19 |
University Patents, Inc. |
Nucleosides useful in the preparation of polynucleotides
|
|
US4973679A
(en)
|
1981-03-27 |
1990-11-27 |
University Patents, Inc. |
Process for oligonucleo tide synthesis using phosphormidite intermediates
|
|
US4668777A
(en)
|
1981-03-27 |
1987-05-26 |
University Patents, Inc. |
Phosphoramidite nucleoside compounds
|
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
SE8205892D0
(sv)
|
1982-10-18 |
1982-10-18 |
Bror Morein |
Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
US5916588A
(en)
|
1984-04-12 |
1999-06-29 |
The Liposome Company, Inc. |
Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use
|
|
US6090406A
(en)
|
1984-04-12 |
2000-07-18 |
The Liposome Company, Inc. |
Potentiation of immune responses with liposomal adjuvants
|
|
US5036006A
(en)
|
1984-11-13 |
1991-07-30 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US4945050A
(en)
|
1984-11-13 |
1990-07-31 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US5185444A
(en)
|
1985-03-15 |
1993-02-09 |
Anti-Gene Deveopment Group |
Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
|
|
AU5661386A
(en)
|
1985-03-15 |
1986-10-13 |
Stirchak, E. |
Stereoregular polynucleotide-binding polymers
|
|
US5153319A
(en)
|
1986-03-31 |
1992-10-06 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US6048729A
(en)
|
1987-05-01 |
2000-04-11 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US4853228A
(en)
|
1987-07-28 |
1989-08-01 |
Micro-Pak, Inc. |
Method of manufacturing unilamellar lipid vesicles
|
|
JPH0731857B2
(ja)
|
1988-02-19 |
1995-04-10 |
三洋電機株式会社 |
磁気記録再生装置におけるリール台駆動装置
|
|
NZ230423A
(en)
|
1988-08-25 |
1993-08-26 |
Liposome Co Inc |
A dosage form comprising an antigen and a multilamellar liposome comprising dimyristolyphosphatidylcholine (dmpc) and cholesterol
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
US5262530A
(en)
|
1988-12-21 |
1993-11-16 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5047524A
(en)
|
1988-12-21 |
1991-09-10 |
Applied Biosystems, Inc. |
Automated system for polynucleotide synthesis and purification
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
US6867195B1
(en)
|
1989-03-21 |
2005-03-15 |
Vical Incorporated |
Lipid-mediated polynucleotide administration to reduce likelihood of subject's becoming infected
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
FR2645020B1
(fr)
|
1989-03-28 |
1994-06-10 |
Vila Jorge |
Medicament pour le traitement des maladies infectieuses dues aux retrovirus ainsi que pour le traitement des tumeurs
|
|
JPH0832638B2
(ja)
|
1989-05-25 |
1996-03-29 |
カイロン コーポレイション |
サブミクロン油滴乳剤を含んで成るアジュバント製剤
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5674192A
(en)
|
1990-12-28 |
1997-10-07 |
Boston Scientific Corporation |
Drug delivery
|
|
US5279833A
(en)
|
1990-04-04 |
1994-01-18 |
Yale University |
Liposomal transfection of nucleic acids into animal cells
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
FR2676072B1
(fr)
|
1991-05-03 |
1994-11-18 |
Transgene Sa |
Vecteur de delivrance d'arn.
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US6054288A
(en)
|
1991-11-05 |
2000-04-25 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
|
PT101031B
(pt)
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
US5750390A
(en)
|
1992-08-26 |
1998-05-12 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for treatment of diseases caused by expression of the bcl-2 gene
|
|
US5693535A
(en)
|
1992-05-14 |
1997-12-02 |
Ribozyme Pharmaceuticals, Inc. |
HIV targeted ribozymes
|
|
US5340740A
(en)
|
1992-05-15 |
1994-08-23 |
North Carolina State University |
Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
|
|
CA2134773A1
(en)
|
1992-06-04 |
1993-12-09 |
Robert J. Debs |
Methods and compositions for in vivo gene therapy
|
|
WO1994002595A1
(en)
|
1992-07-17 |
1994-02-03 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for treatment of animal diseases
|
|
US5474914A
(en)
|
1992-07-29 |
1995-12-12 |
Chiron Corporation |
Method of producing secreted CMV glycoprotein H
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US20020102273A1
(en)
|
1995-08-08 |
2002-08-01 |
Robert B. Grieve |
Use of alphavirus expression vectors to produce parasite anitgens
|
|
EP0689454B2
(en)
|
1993-03-23 |
2005-02-23 |
SMITHKLINE BEECHAM BIOLOGICALS s.a. |
Vaccine compositions containing 3-o deacylated monophosphoryl lipid a
|
|
JPH09500013A
(ja)
|
1993-06-01 |
1997-01-07 |
ライフ・テクノロジーズ・インコーポレイテッド |
カチオン性脂質による遺伝子免疫
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
CZ288182B6
(en)
|
1993-07-15 |
2001-05-16 |
Minnesota Mining & Mfg |
Imidazo[4,5-c]pyridine-4-amines and pharmaceutical preparations based thereon
|
|
US6015686A
(en)
|
1993-09-15 |
2000-01-18 |
Chiron Viagene, Inc. |
Eukaryotic layered vector initiation systems
|
|
US5397307A
(en)
|
1993-12-07 |
1995-03-14 |
Schneider (Usa) Inc. |
Drug delivery PTCA catheter and method for drug delivery
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
JP3403233B2
(ja)
|
1994-01-20 |
2003-05-06 |
テルモ株式会社 |
バルーンカテーテル
|
|
AU2215995A
(en)
|
1994-04-07 |
1995-10-30 |
Akzo Nobel N.V. |
Freeze-dried compositions comprising rna
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5993850A
(en)
|
1994-09-13 |
1999-11-30 |
Skyepharma Inc. |
Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances
|
|
US5885613A
(en)
|
1994-09-30 |
1999-03-23 |
The University Of British Columbia |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
|
|
AUPM873294A0
(en)
|
1994-10-12 |
1994-11-03 |
Csl Limited |
Saponin preparations and use thereof in iscoms
|
|
FR2726003B1
(fr)
|
1994-10-21 |
2002-10-18 |
Agronomique Inst Nat Rech |
Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires
|
|
DE69536153D1
(de)
|
1994-11-17 |
2011-05-05 |
Ich Productions Ltd |
Internalisierung von dna, unter verwendung von konjugaten des poly-l-lysins und eines peptidligands des integrin-rezeptors
|
|
AU4594996A
(en)
|
1994-11-30 |
1996-06-19 |
Chiron Viagene, Inc. |
Recombinant alphavirus vectors
|
|
US6071890A
(en)
|
1994-12-09 |
2000-06-06 |
Genzyme Corporation |
Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
|
|
US5965434A
(en)
|
1994-12-29 |
1999-10-12 |
Wolff; Jon A. |
Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
UA56132C2
(uk)
|
1995-04-25 |
2003-05-15 |
Смітклайн Бічем Байолоджікалс С.А. |
Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
|
|
US5700642A
(en)
|
1995-05-22 |
1997-12-23 |
Sri International |
Oligonucleotide sizing using immobilized cleavable primers
|
|
US5792462A
(en)
|
1995-05-23 |
1998-08-11 |
University Of North Carolina At Chapel Hill |
Alphavirus RNA replicon systems
|
|
US5981501A
(en)
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
|
US6264957B1
(en)
|
1995-09-27 |
2001-07-24 |
The United States Of America As Represented By The Department Of Health And Human Services |
Product of infectious respiratory syncytial virus from cloned nucleotide sequences
|
|
DE69716240T2
(de)
|
1996-02-12 |
2003-06-26 |
Ml Lab Plc London |
Neue methode zur impfung sowie impfstoffe dafür, die eine epitopkodierende nukleinsäure und ein epitopenthaltende peptid beinhalten
|
|
DE19605548A1
(de)
|
1996-02-15 |
1997-09-04 |
Boehringer Ingelheim Int |
Zusammensetzung für die Transfektion höherer eukaryotischer Zellen
|
|
US6451592B1
(en)
*
|
1996-04-05 |
2002-09-17 |
Chiron Corporation |
Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
|
|
JP2001503735A
(ja)
|
1996-07-03 |
2001-03-21 |
ユニバーシティ オブ ピッツバーグ |
親水性活性試薬のためのエマルジョン処方物
|
|
WO1998001148A1
(en)
|
1996-07-09 |
1998-01-15 |
President And Fellows Of Harvard College |
Use of papillomavirus e2 protein in treating papillomavirus-infected cells and compositions containing the protein
|
|
CN1138533C
(zh)
|
1996-09-13 |
2004-02-18 |
利普森有限公司 |
脂质体
|
|
US7384923B2
(en)
|
1999-05-14 |
2008-06-10 |
Lipoxen Technologies Limited |
Liposomes
|
|
US6395302B1
(en)
|
1996-11-19 |
2002-05-28 |
Octoplus B.V. |
Method for the preparation of microspheres which contain colloidal systems
|
|
AU753688B2
(en)
|
1997-03-10 |
2002-10-24 |
Ottawa Civic Loeb Research Institute |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
US6818222B1
(en)
|
1997-03-21 |
2004-11-16 |
Chiron Corporation |
Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants
|
|
WO1998051278A2
(en)
|
1997-05-14 |
1998-11-19 |
Inex Pharmaceuticals Corporation |
High efficiency encapsulation of charged therapeutic agents in lipid vesicles
|
|
US6048546A
(en)
|
1997-07-31 |
2000-04-11 |
Sandia Corporation |
Immobilized lipid-bilayer materials
|
|
US6060308A
(en)
|
1997-09-04 |
2000-05-09 |
Connaught Laboratories Limited |
RNA respiratory syncytial virus vaccines
|
|
US6090619A
(en)
|
1997-09-08 |
2000-07-18 |
University Of Florida |
Materials and methods for intracellular delivery of biologically active molecules
|
|
US6129705A
(en)
|
1997-10-01 |
2000-10-10 |
Medtronic Ave, Inc. |
Drug delivery and gene therapy delivery system
|
|
GB9725084D0
(en)
|
1997-11-28 |
1998-01-28 |
Medeva Europ Ltd |
Vaccine compositions
|
|
US6009406A
(en)
|
1997-12-05 |
1999-12-28 |
Square D Company |
Methodology and computer-based tools for re-engineering a custom-engineered product line
|
|
GB9726555D0
(en)
|
1997-12-16 |
1998-02-11 |
Smithkline Beecham Plc |
Vaccine
|
|
HUP0101619A3
(en)
|
1998-04-09 |
2003-11-28 |
Smithkline Beecham Biolog |
Adjuvant compositions
|
|
US6432925B1
(en)
|
1998-04-16 |
2002-08-13 |
John Wayne Cancer Institute |
RNA cancer vaccine and methods for its use
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
CA2336554A1
(en)
|
1998-06-29 |
2000-01-06 |
U.S. Medical Research Institute Of Infectious Diseases |
Marburg virus vaccines
|
|
WO2000003683A2
(en)
|
1998-07-20 |
2000-01-27 |
Inex Pharmaceuticals Corporation |
Liposomal encapsulated nucleic acid-complexes
|
|
GB9817052D0
(en)
|
1998-08-05 |
1998-09-30 |
Smithkline Beecham Biolog |
Vaccine
|
|
DE122007000087I1
(de)
|
1998-10-16 |
2008-03-27 |
Glaxosmithkline Biolog Sa |
Adjuvanzsysteme und impfstoffe
|
|
CA2360347C
(en)
|
1998-12-31 |
2013-05-07 |
Chiron Corporation |
Improved expression of hiv polypeptides and production of virus-like particles
|
|
ATE289630T1
(de)
|
1999-09-09 |
2005-03-15 |
Curevac Gmbh |
Transfer von mrnas unter verwendung von polykationischen verbindungen
|
|
PL355163A1
(en)
|
1999-09-24 |
2004-04-05 |
Smithkline Beecham Biologicals S.A. |
Use of combination of polyoxyethylene sorbitan ester and octoxynol as adjuvant and its use in vaccines
|
|
BR0014285A
(pt)
|
1999-09-24 |
2002-05-21 |
Smithkline Beecham Biolog |
Adjuvantes compreendendo um éster ou éter de alquila de polioxietileno e pelo menos um tensoativo não-iÈnico
|
|
JP2004500047A
(ja)
|
1999-10-20 |
2004-01-08 |
ザ ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン |
キメラ免疫原性組成物およびこれらをコードする核酸
|
|
US8541008B2
(en)
|
1999-11-19 |
2013-09-24 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Pharmaceutical compositions and methods to vaccinate against candidiasis
|
|
WO2001095935A1
(en)
|
2000-01-20 |
2001-12-20 |
Ottawa Health Research Institute |
Immunostimulatory nucleic acids for inducing a th2 immune response
|
|
US20030212022A1
(en)
|
2001-03-23 |
2003-11-13 |
Jean-Marie Vogel |
Compositions and methods for gene therapy
|
|
AU2001253323A1
(en)
|
2000-04-18 |
2001-10-30 |
Human Genome Sciences, Inc. |
Extracellular matrix polynucleotides, polypeptides, and antibodies
|
|
JP2003535832A
(ja)
|
2000-06-09 |
2003-12-02 |
ブリカス，テニ |
ポリヌクレオチドおよび薬物の標的化リポソームへのカプセル化
|
|
ATE440861T1
(de)
|
2000-07-03 |
2009-09-15 |
Novartis Vaccines & Diagnostic |
Immunisierung gegen chlamydia pneumoniae
|
|
WO2002009645A2
(en)
*
|
2000-08-01 |
2002-02-07 |
The Johns Hopkins University |
Intercellular transport protein linked to an antigen as a molecular vaccine
|
|
US20040142474A1
(en)
|
2000-09-14 |
2004-07-22 |
Expression Genetics, Inc. |
Novel cationic lipopolymer as a biocompatible gene delivery agent
|
|
JP2004509970A
(ja)
|
2000-09-26 |
2004-04-02 |
ハイブリドン・インコーポレイテッド |
位置的化学変化による免疫刺激オリゴヌクレオチドアナログの免疫刺激活性の調節
|
|
MXPA03002640A
(es)
|
2000-09-28 |
2003-06-19 |
Chiron Corp |
Microparticulas para la distribucion de acidos nucleicos heterologos.
|
|
US7939087B2
(en)
|
2000-10-27 |
2011-05-10 |
Novartis Vaccines And Diagnostics, Inc. |
Nucleic acids and proteins from Streptococcus groups A & B
|
|
WO2002079239A2
(en)
|
2001-01-31 |
2002-10-10 |
U.S. Army Medical Research Institute Of Infectious Diseases |
Chimeric filovirus glycoprotein
|
|
WO2002061113A2
(en)
|
2001-02-01 |
2002-08-08 |
The Johns Hopkins University |
Nucleic acid derived vaccine that encodes an antigen linked to a polypeptide that promotes antigen presentation
|
|
US20030040498A1
(en)
|
2001-03-14 |
2003-02-27 |
Ansardi David Calvert |
Oncolytic RNA replicons
|
|
WO2002088318A2
(en)
|
2001-04-30 |
2002-11-07 |
Targeted Genetics Corporation |
Lipid-comprising drug delivery complexes and methods for their production
|
|
US7514099B2
(en)
|
2005-02-14 |
2009-04-07 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
US20030077251A1
(en)
|
2001-05-23 |
2003-04-24 |
Nicolas Escriou |
Replicons derived from positive strand RNA virus genomes useful for the production of heterologous proteins
|
|
EP2842964A1
(de)
|
2001-06-05 |
2015-03-04 |
Curevac GmbH |
Virtuelles Verfahren zur Ermittlung einer modifzierten mRNA-Sequenz
|
|
US20050175629A1
(en)
|
2001-08-31 |
2005-08-11 |
Giuseppe Del Giudice |
Helicobacter pylori vaccination
|
|
WO2003023026A1
(en)
|
2001-09-06 |
2003-03-20 |
Alphavax, Inc. |
Alphavirus replicon vector systems
|
|
DE60234375D1
(de)
|
2001-09-14 |
2009-12-24 |
Cytos Biotechnology Ag |
VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG
|
|
AU2002347404A1
(en)
|
2001-09-14 |
2003-04-01 |
Cytos Biotechnology Ag |
In vivo activation of antigen presenting cells for enhancement of immune responses induced by virus like particles
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
FR2832423B1
(fr)
|
2001-11-22 |
2004-10-08 |
Vivalis |
Systeme d'expression de proteines exogenes dans un systeme aviaire
|
|
US20050163832A1
(en)
|
2002-02-13 |
2005-07-28 |
Vladimir Torchilin |
Intracellular delivery of therapeutic agents
|
|
DE10207177A1
(de)
|
2002-02-19 |
2003-09-04 |
Novosom Ag |
Fakultativ kationische Lipide
|
|
FR2836924B1
(fr)
|
2002-03-08 |
2005-01-14 |
Vivalis |
Lignees de cellules aviaires utiles pour la production de substances d'interet
|
|
DE60334618D1
(de)
|
2002-06-28 |
2010-12-02 |
Protiva Biotherapeutics Inc |
Verfahren und vorrichtung zur herstellung von liposomen
|
|
AU2003244855A1
(en)
|
2002-07-05 |
2004-01-23 |
Lipoxen Technologies Limited |
Method to enhance an immune response of nucleic acid vaccination
|
|
EP1530585A2
(en)
|
2002-08-22 |
2005-05-18 |
Cytos Biotechnology AG |
Inducible alphaviral/orip based gene expression system
|
|
AU2003267785C1
(en)
|
2002-09-13 |
2009-12-24 |
Replicor, Inc. |
Non-sequence complementary antiviral oligonucleotides
|
|
JP4991108B2
(ja)
*
|
2002-12-13 |
2012-08-01 |
アルファバックス，インコーポレイティド |
多抗原性アルファウイルス・レプリコン粒子及び方法
|
|
PT2311848E
(pt)
|
2002-12-23 |
2013-10-03 |
Vical Inc |
Vacinas à base de polinucleótido optimizadas por codão contra a infecção do citomegalovírus humano
|
|
AU2003300021A1
(en)
|
2002-12-27 |
2004-07-29 |
Chiron Corporation |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
US8193185B2
(en)
|
2003-01-21 |
2012-06-05 |
Novartis Vaccines And Diagnostics, Inc. |
Use of tryptanthrin compounds for immune potentiation
|
|
US8338583B2
(en)
|
2003-02-04 |
2012-12-25 |
Bar-Ilan University |
Snornai-small nucleolar RNA degradation by RNA interference in trypanosomatids
|
|
US20040228842A1
(en)
|
2003-02-27 |
2004-11-18 |
Shan Lu |
Compositions and methods for cytomegalovirus treatment
|
|
CN1791678A
(zh)
*
|
2003-03-20 |
2006-06-21 |
阿尔法瓦克斯公司 |
改进的甲病毒复制子和辅助构建体
|
|
DE10319208B4
(de)
|
2003-04-29 |
2005-10-20 |
Grenzebach Bsh Gmbh |
Furniermessermaschine
|
|
KR20060063788A
(ko)
|
2003-05-30 |
2006-06-12 |
니뽄 신야쿠 가부시키가이샤 |
올리고 핵산 담지 복합체, 이 복합체를 함유하는 의약조성물
|
|
WO2005002619A2
(en)
|
2003-06-26 |
2005-01-13 |
Chiron Corporation |
Immunogenic compositions for chlamydia trachomatis
|
|
PT1651666E
(pt)
|
2003-07-11 |
2009-08-28 |
Alphavax Inc |
Vacinas de citomegalovírus à base de alfavírus
|
|
US7368537B2
(en)
|
2003-07-15 |
2008-05-06 |
Id Biomedical Corporation Of Quebec |
Subunit vaccine against respiratory syncytial virus infection
|
|
CN101291653B
(zh)
|
2003-07-16 |
2012-06-27 |
普洛体维生物治疗公司 |
脂质包封的干扰rna
|
|
PT1648500E
(pt)
|
2003-07-31 |
2014-10-10 |
Novartis Vaccines & Diagnostic |
Composições imunogénicas para estreptococos piogenes
|
|
EP1512393A1
(de)
|
2003-09-08 |
2005-03-09 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
Verfahren zur Herstellung von homogenen Liposomen und Lipoplexen
|
|
EP1528101A1
(en)
|
2003-11-03 |
2005-05-04 |
ProBioGen AG |
Immortalized avian cell lines for virus production
|
|
US20050208020A1
(en)
|
2003-11-12 |
2005-09-22 |
Doolan Denise L |
Enhancement of vaccine-induced immune responses and protection by heterologous boosting with alphavirus replicon vaccines
|
|
US7303881B2
(en)
|
2004-04-30 |
2007-12-04 |
Pds Biotechnology Corporation |
Antigen delivery compositions and methods of use
|
|
GB0410866D0
(en)
|
2004-05-14 |
2004-06-16 |
Chiron Srl |
Haemophilius influenzae
|
|
AU2005245956B2
(en)
|
2004-05-18 |
2011-05-19 |
Alphavax, Inc. |
TC-83-derived alphavirus vectors, particles and methods
|
|
JP5331340B2
(ja)
|
2004-05-18 |
2013-10-30 |
バイカル インコーポレイテッド |
インフルエンザウィルスワクチン組成物、及びその使用方法
|
|
GB0411428D0
(en)
|
2004-05-21 |
2004-06-23 |
Got A Gene Ab |
Vectors
|
|
JP4896021B2
(ja)
|
2004-05-21 |
2012-03-14 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド |
呼吸器系病原体ワクチンのためのアルファウイルスベクター
|
|
EP1781593B1
(en)
|
2004-06-07 |
2011-12-14 |
Protiva Biotherapeutics Inc. |
Cationic lipids and methods of use
|
|
EP1766035B1
(en)
|
2004-06-07 |
2011-12-07 |
Protiva Biotherapeutics Inc. |
Lipid encapsulated interfering rna
|
|
US7862829B2
(en)
|
2004-07-09 |
2011-01-04 |
University Of North Carolina At Chapel Hill |
Viral adjuvants
|
|
US20060051405A1
(en)
|
2004-07-19 |
2006-03-09 |
Protiva Biotherapeutics, Inc. |
Compositions for the delivery of therapeutic agents and uses thereof
|
|
DE602005020815D1
(de)
|
2004-09-24 |
2010-06-02 |
Intercell Ag |
Verändertes vp-1capsidprotein von parvovirus b19
|
|
EP1794183A2
(en)
|
2004-10-01 |
2007-06-13 |
Novartis Vaccines and Diagnostics S.r.l. |
Hepatitis c virus replication system
|
|
WO2006053646A2
(en)
|
2004-11-19 |
2006-05-26 |
Novosom Ag |
Improvements in or relating to pharmaceutical compositions for local administration
|
|
GB2421025A
(en)
|
2004-12-09 |
2006-06-14 |
Oxxon Therapeutics Ltd |
HSV vaccination vectors
|
|
US7404969B2
(en)
|
2005-02-14 |
2008-07-29 |
Sirna Therapeutics, Inc. |
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
|
|
NZ580974A
(en)
|
2005-02-18 |
2011-05-27 |
Novartis Vaccines & Diagnostic |
Immunogens from uropathogenic escherichia coli
|
|
SI1858920T1
(sl)
|
2005-02-18 |
2016-07-29 |
Glaxosmithkline Biologicals S.A. |
Proteini in nukleinske kisline iz escherichia coli, povezane z meningitisom/sepso
|
|
AU2006219717B2
(en)
|
2005-03-02 |
2009-05-21 |
The Secretary Of State For Defence |
Pharmaceutical composition
|
|
GB0504436D0
(en)
|
2005-03-03 |
2005-04-06 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
BRPI0609460A2
(pt)
|
2005-03-30 |
2010-04-13 |
Novartis Vaccines & Diagnostics Inc |
haemophilus influenzae tipo b
|
|
US7618393B2
(en)
|
2005-05-03 |
2009-11-17 |
Pharmajet, Inc. |
Needle-less injector and method of fluid delivery
|
|
CA2608278A1
(en)
|
2005-05-12 |
2006-12-28 |
Guido Grandi |
Immunogenic compositions for chlamydia trachomatis
|
|
US8703095B2
(en)
|
2005-07-07 |
2014-04-22 |
Sanofi Pasteur S.A. |
Immuno-adjuvant emulsion
|
|
EP1909758A1
(en)
|
2005-08-02 |
2008-04-16 |
I.D.M. Immuno-Designed Molecules |
Process for the preparation of liposomal formulations
|
|
US7951384B2
(en)
|
2005-08-05 |
2011-05-31 |
University Of Massachusetts |
Virus-like particles as vaccines for paramyxovirus
|
|
RS63964B1
(sr)
|
2005-08-23 |
2023-03-31 |
Univ Pennsylvania |
Rnk koja sadrži modifikovane nukleozide i postupci za njenu upotrebu
|
|
EP1764089A1
(en)
|
2005-09-15 |
2007-03-21 |
Novosom AG |
Serum stable liposomes comprising amphoter II lipid mixtures
|
|
WO2007107304A2
(en)
|
2006-03-17 |
2007-09-27 |
Novosom Ag |
An efficient method for loading amphoteric liposomes with nucleic acid active substances
|
|
DE102005046490A1
(de)
|
2005-09-28 |
2007-03-29 |
Johannes-Gutenberg-Universität Mainz |
Modifikationen von RNA, die zu einer erhöhten Transkriptstabilität und Translationseffizienz führen
|
|
WO2007041270A1
(en)
|
2005-09-29 |
2007-04-12 |
Elan Pharmaceuticals, Inc. |
Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by vla-4
|
|
JP2009511636A
(ja)
|
2005-10-18 |
2009-03-19 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド |
アルファウイルスレプリコン粒子による粘膜免疫および全身免疫
|
|
JP2007112768A
(ja)
|
2005-10-24 |
2007-05-10 |
Kyoto Univ |
肝指向性リポソーム組成物
|
|
AU2006307602A1
(en)
|
2005-10-25 |
2007-05-03 |
Novartis Vaccines And Diagnostics Srl |
Compositions comprising Yersinia pestis antigens
|
|
JP5215865B2
(ja)
|
2005-11-22 |
2013-06-19 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス インコーポレイテッド |
ノロウイルス抗原およびサポウイルス抗原
|
|
ES2564241T3
(es)
|
2005-12-02 |
2016-03-21 |
Glaxosmithkline Biologicals Sa |
Nanopartículas para su uso en composiciones inmunogénicas
|
|
EP3031469B1
(en)
|
2006-06-07 |
2023-08-23 |
The Trustees Of Princeton University |
Cytomegalovirus surface protein complex for use in vaccines and as a drug target
|
|
US7915399B2
(en)
|
2006-06-09 |
2011-03-29 |
Protiva Biotherapeutics, Inc. |
Modified siRNA molecules and uses thereof
|
|
DK2035581T3
(da)
|
2006-06-21 |
2012-10-08 |
Scripps Research Inst |
Dna-sammensætning mod tumorstromaantigen fap og fremgangsmåder til anvendelse deraf
|
|
EP2586790A3
(en)
|
2006-08-16 |
2013-08-14 |
Novartis AG |
Immunogens from uropathogenic Escherichia coli
|
|
PL3207941T6
(pl)
|
2006-09-07 |
2020-11-16 |
Scott & White Memorial Hospital |
Sposoby i kompozycje oparte na koniugacie ludzkiej interleukiny (IL)-3 z toksyną błoniczą
|
|
WO2008033966A2
(en)
|
2006-09-12 |
2008-03-20 |
Alphavax, Inc. |
Alphavirus replicon particles matched to protein antigens as immunological adjuvants
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
JP2010519203A
(ja)
*
|
2007-02-16 |
2010-06-03 |
メルク・シャープ・エンド・ドーム・コーポレイション |
生物活性分子の活性を強化するための組成物及び方法
|
|
WO2008109806A2
(en)
|
2007-03-08 |
2008-09-12 |
Massachusetts Institute Of Technology |
Electrostatic coating of particles for drug delivery
|
|
US8877206B2
(en)
|
2007-03-22 |
2014-11-04 |
Pds Biotechnology Corporation |
Stimulation of an immune response by cationic lipids
|
|
AP3018A
(en)
|
2007-03-29 |
2014-10-31 |
Alnylam Pharmaceuticals Inc |
Compositions and methods for inhibiting expressionof a gene from the ebola
|
|
US8748591B2
(en)
|
2007-04-17 |
2014-06-10 |
The Board Of Regents Of The University Of Texas System |
Chimeric sindbis-western equine encephalitis virus and uses thereof
|
|
LT2494993T
(lt)
|
2007-05-04 |
2018-12-27 |
Marina Biotech, Inc. |
Aminorūgščių lipidai ir jų panaudojimas
|
|
EP2152890A1
(en)
|
2007-05-23 |
2010-02-17 |
MannKind Corporation |
Multicistronic vectors and methods for their design
|
|
DE102007029471A1
(de)
|
2007-06-20 |
2008-12-24 |
Novosom Ag |
Neue fakultativ kationische Sterole
|
|
NZ582495A
(en)
|
2007-06-21 |
2012-05-25 |
Alphavax Inc |
Promoterless cassettes for expression of alphavirus structural proteins
|
|
US8202518B2
(en)
|
2007-07-04 |
2012-06-19 |
Ribovax Biotechnologies S.A. |
Antibodies against human cytomegalovirus (HCMV)
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
US20110177155A1
(en)
|
2007-08-21 |
2011-07-21 |
Immune Disease Institute, Inc. |
Methods of delivery of agents to leukocytes and endothelial cells
|
|
GB0717187D0
(en)
|
2007-09-04 |
2007-10-17 |
Novartis Ag |
Compositions comprising yersinia pestis antigens
|
|
CA2704153A1
(en)
|
2007-09-26 |
2009-04-02 |
Vanderbilt University |
Vaccine for rsv and mpv
|
|
EP2042193A1
(en)
|
2007-09-28 |
2009-04-01 |
Biomay AG |
RNA Vaccines
|
|
US20090091591A1
(en)
|
2007-10-07 |
2009-04-09 |
Yohanan Sivan |
Printing Systems And Methods For Generating Relief Images
|
|
AU2008338803B2
(en)
|
2007-11-26 |
2015-02-05 |
Glaxosmithkline Biologicals S.A. |
Methods of generating alphavirus particles
|
|
EP2067749A1
(en)
|
2007-11-29 |
2009-06-10 |
Total Petrochemicals France |
Process for purification of an aqueous phase containing polyaromatics
|
|
WO2009074861A2
(en)
|
2007-12-10 |
2009-06-18 |
Powderject Research Limited |
Improved vaccine
|
|
EP2224912B1
(en)
|
2008-01-02 |
2016-05-11 |
TEKMIRA Pharmaceuticals Corporation |
Improved compositions and methods for the delivery of nucleic acids
|
|
US20110165223A1
(en)
|
2008-01-02 |
2011-07-07 |
The Johns Hopkins University |
Antitumor Immunization by Liposomal Delivery of Vaccine to the Spleen
|
|
ITMI20081249A1
(it)
|
2008-07-09 |
2010-01-09 |
Novartis Vaccines & Diagnostic |
Immunogeni di escherichia coli con solubilità migliorata.
|
|
EA018068B1
(ru)
|
2008-03-03 |
2013-05-30 |
Айрм Ллк |
Соединения и композиции в качестве модуляторов активности tlr
|
|
EP2268659A2
(en)
|
2008-03-06 |
2011-01-05 |
Novartis AG |
Mutant forms of chlamydia htra
|
|
CA2721333C
(en)
|
2008-04-15 |
2020-12-01 |
Protiva Biotherapeutics, Inc. |
Novel lipid formulations for nucleic acid delivery
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
WO2009132131A1
(en)
|
2008-04-22 |
2009-10-29 |
Alnylam Pharmaceuticals, Inc. |
Amino lipid based improved lipid formulation
|
|
WO2009132206A1
(en)
|
2008-04-25 |
2009-10-29 |
Liquidia Technologies, Inc. |
Compositions and methods for intracellular delivery and release of cargo
|
|
US20100040650A1
(en)
|
2008-05-30 |
2010-02-18 |
Crowe Jr James E |
Virus-Like paramyxovirus particles and vaccines
|
|
EP2130912A1
(en)
|
2008-06-04 |
2009-12-09 |
Institut für Viruskrankeiten und Immunprophylaxe |
Pestivirus replicons providing an RNA-based viral vector system
|
|
EP2310494A1
(en)
|
2008-06-25 |
2011-04-20 |
ProBioGen AG |
Cell line for propagation of highly attenuated alphaviruses
|
|
US9421251B2
(en)
|
2008-06-25 |
2016-08-23 |
Novartis Ag |
Rapid responses to delayed booster immunisations
|
|
JP5475774B2
(ja)
|
2008-07-16 |
2014-04-16 |
インスティテュート フォー リサーチ イン バイオメディシン |
ヒトサイトメガロウイルス中和抗体およびその使用
|
|
US8124093B2
(en)
|
2008-07-16 |
2012-02-28 |
Institute For Research In Biomedicine |
Human cytomegalovirus neutralizing antibodies and use thereof
|
|
JP2010025644A
(ja)
|
2008-07-16 |
2010-02-04 |
Kochi Univ Of Technology |
硝酸イオンの呈色試薬並びにこれを用いた硝酸イオンの検出及び定量方法
|
|
EP2328614A1
(en)
*
|
2008-08-06 |
2011-06-08 |
Novartis AG |
Microparticles for use in immunogenic compositions
|
|
CL2008002322A1
(es)
|
2008-08-07 |
2009-06-05 |
Univ Concepcion |
Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.
|
|
KR101661746B1
(ko)
|
2008-08-13 |
2016-09-30 |
캘리포니아 인스티튜트 오브 테크놀로지 |
캐리어 나노입자, 그리고 관련된 조성물, 방법 및 시스템
|
|
WO2010036948A2
(en)
|
2008-09-26 |
2010-04-01 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Dna prime/inactivated vaccine boost immunization to influenza virus
|
|
JP5777519B2
(ja)
|
2008-10-09 |
2015-09-09 |
テクミラ ファーマシューティカルズ コーポレイション |
改良されたアミノ脂質および核酸の送達方法
|
|
WO2010053572A2
(en)
|
2008-11-07 |
2010-05-14 |
Massachusetts Institute Of Technology |
Aminoalcohol lipidoids and uses thereof
|
|
DK2355851T3
(en)
|
2008-11-10 |
2018-06-25 |
Arbutus Biopharma Corp |
Newly known lipids and compositions for release of therapeutic agents
|
|
EP2367844A4
(en)
|
2008-11-18 |
2012-08-01 |
Ligocyte Pharmaceuticals Inc |
RSV-F VLP AND MANUFACTURING METHOD AND METHOD OF USE THEREOF
|
|
US20120101148A1
(en)
|
2009-01-29 |
2012-04-26 |
Alnylam Pharmaceuticals, Inc. |
lipid formulation
|
|
WO2010119343A2
(en)
|
2009-04-14 |
2010-10-21 |
Novartis Ag |
Compositions for immunising against staphylococcus aureus
|
|
CA3045126A1
(en)
|
2009-05-05 |
2010-11-11 |
Arbutus Biopharma Corporation |
Methods of delivering oligonucleotides to immune cells
|
|
CA2764609C
(en)
|
2009-06-10 |
2018-10-02 |
Alnylam Pharmaceuticals, Inc. |
Improved cationic lipid of formula i
|
|
JP5766188B2
(ja)
|
2009-07-01 |
2015-08-19 |
プロチバ バイオセラピューティクス インコーポレイティッド |
固形腫瘍に治療剤を送達するための脂質製剤
|
|
WO2011001780A1
(ja)
|
2009-07-02 |
2011-01-06 |
コニカミノルタホールディングス株式会社 |
特定分散剤を含有する外水相を利用する二段階乳化法によるリポソームの製造方法、ならびに当該リポソームの製造方法を用いるリポソーム分散液またはその乾燥粉末の製造方法およびそれにより製造されるリポソーム分散液またはその乾燥粉末
|
|
WO2011005799A2
(en)
|
2009-07-06 |
2011-01-13 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
|
PL3178490T3
(pl)
|
2009-07-15 |
2022-08-01 |
Glaxosmithkline Biologicals S.A. |
Kompozycje białka f rsv i sposoby ich wytwarzania
|
|
US8277919B2
(en)
|
2009-07-23 |
2012-10-02 |
VMO Systems, Inc. |
Reflective coating for an optical disc
|
|
BR112012002291A2
(pt)
|
2009-07-31 |
2016-11-29 |
Ethris Gmbh |
"polirribonucleotídeo com uma sequência que codifica uma proteína ou fragmento de proteína, implante, e, processo para a seleção de sequências de nucleotídeos"
|
|
SG178954A1
(en)
*
|
2009-09-02 |
2012-04-27 |
Novartis Ag |
Immunogenic compositions including tlr activity modulators
|
|
TWI445708B
(zh)
*
|
2009-09-02 |
2014-07-21 |
Irm Llc |
作為ｔｌｒ活性調節劑之化合物及組合物
|
|
US20110070260A1
(en)
|
2009-09-09 |
2011-03-24 |
Baric Ralph S |
Multivalent Immunogenic Compositions Against Noroviruses and Methods of Use
|
|
EP2496700B1
(en)
|
2009-11-04 |
2017-03-01 |
The University Of British Columbia |
Nucleic acid-containing lipid particles and related methods
|
|
ME03091B
(me)
|
2009-12-01 |
2019-01-20 |
Translate Bio Inc |
Isporuka irnk za povećanje ekspresije proteina i enzima u humanim genetskim oboljenjima
|
|
CA2783372C
(en)
|
2009-12-07 |
2019-07-16 |
Muthiah Manoharan |
Compositions for nucleic acid delivery
|
|
SI3112467T1
(en)
|
2009-12-07 |
2018-06-29 |
The Trustees Of The University Of Pennsylvania |
Rna preparations comprising purified modified rna for reprogramming cells
|
|
AU2010330814B2
(en)
|
2009-12-18 |
2017-01-12 |
Acuitas Therapeutics Inc. |
Methods and compositions for delivery of nucleic acids
|
|
WO2011076807A2
(en)
|
2009-12-23 |
2011-06-30 |
Novartis Ag |
Lipids, lipid compositions, and methods of using them
|
|
JP5988435B2
(ja)
*
|
2010-01-24 |
2016-09-07 |
ノバルティス アーゲー |
放射線照射された生分解性微粒子
|
|
US20130195961A1
(en)
|
2010-03-09 |
2013-08-01 |
Kejian Yang |
Novel mucosal vaccination approach for herpes simplex virus type-2
|
|
EP2556151A1
(en)
*
|
2010-04-07 |
2013-02-13 |
Novartis AG |
Method for generating a parvovirus b19 virus-like particle
|
|
HUE047796T2
(hu)
|
2010-07-06 |
2020-05-28 |
Glaxosmithkline Biologicals Sa |
RNS bevitele több immunútvonal bekapcsolására
|
|
CN103154242B
(zh)
*
|
2010-07-06 |
2015-09-30 |
诺华股份有限公司 |
诺如病毒衍生的免疫原性组合物和方法
|
|
DK2590676T3
(en)
|
2010-07-06 |
2016-10-24 |
Glaxosmithkline Biologicals Sa |
Virionlignende feed particles to self-replicating RNA molecules
|
|
JP5940064B2
(ja)
|
2010-07-06 |
2016-06-29 |
ノバルティス アーゲー |
低用量のｒｎａを用いた大型哺乳動物の免疫化
|
|
US9192661B2
(en)
*
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
|
NZ606591A
(en)
*
|
2010-07-06 |
2015-02-27 |
Novartis Ag |
Cationic oil-in-water emulsions
|
|
US9770463B2
(en)
*
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
|
RS54489B1
(sr)
*
|
2010-07-06 |
2016-06-30 |
Glaxosmithkline Biologicals Sa |
Lipozomi sa lipidima koji imaju poboljšanu pka vrednost za oslobađanje rnk
|
|
US8898852B2
(en)
|
2010-08-04 |
2014-12-02 |
Honeywell International Inc. |
Air burst to clear detection window
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
HRP20221048T1
(hr)
*
|
2010-08-31 |
2022-11-11 |
Glaxosmithkline Biologicals Sa |
Mali liposomi za isporuku rna koja kodira imunogen
|
|
SMT202200311T1
(it)
|
2010-08-31 |
2022-09-14 |
Glaxosmithkline Biologicals Sa |
Liposomi pegilati per somministrare rna codificante un immunogene
|
|
BR112013004865A2
(pt)
|
2010-08-31 |
2016-06-07 |
Novartis Ag |
lípidos adequados para entrega lipossomal de codificadores de proteínas rna
|
|
EP2614072A4
(en)
|
2010-09-09 |
2014-03-19 |
Univ Virginia Commonwealth |
VACCINE AGAINST THE HUMAN CYTOMEGALOVIRUS
|
|
DK4108671T3
(da)
|
2010-10-01 |
2025-01-06 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
|
|
EP3520813B1
(en)
|
2010-10-11 |
2023-04-19 |
GlaxoSmithKline Biologicals S.A. |
Antigen delivery platforms
|
|
PH12013500764A1
(en)
|
2010-10-25 |
2015-09-23 |
Stepan Co |
Quaternized fatty amines, amidoamines, and their derivatives from natural oil metathesis
|
|
US20120177701A1
(en)
|
2010-12-31 |
2012-07-12 |
Selecta Biosciences, Inc. |
Compositions comprising immunostimulatory nucleic acids and related methods
|
|
PL2667892T3
(pl)
*
|
2011-01-26 |
2019-09-30 |
Glaxosmithkline Biologicals Sa |
Schemat szczepień przeciwko rsv
|
|
WO2012106377A2
(en)
|
2011-01-31 |
2012-08-09 |
The Trustees Of The University Of Pennsylvania |
Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof
|
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
|
ES2651143T3
(es)
*
|
2011-05-13 |
2018-01-24 |
Glaxosmithkline Biologicals Sa |
Antígenos de F de prefusión del VRS
|
|
CA2835428A1
(en)
|
2011-05-17 |
2012-11-22 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof for non-human vertebrates
|
|
PT2717893T
(pt)
|
2011-06-08 |
2019-08-20 |
Translate Bio Inc |
Composições de nanopartículas lipídicas e métodos para transferência de arnm
|
|
EP3998064A1
(en)
|
2011-06-08 |
2022-05-18 |
Translate Bio, Inc. |
Cleavable lipids
|
|
CN103781470A
(zh)
*
|
2011-07-06 |
2014-05-07 |
诺华股份有限公司 |
包含核酸的水包油乳液
|
|
US20140141070A1
(en)
|
2011-07-06 |
2014-05-22 |
Andrew Geall |
Liposomes having useful n:p ratio for delivery of rna molecules
|
|
EP3508219A1
(en)
|
2011-07-06 |
2019-07-10 |
GlaxoSmithKline Biologicals S.A. |
Self-replicating rna prime - protein boost vaccines
|
|
EP3854413A1
(en)
*
|
2011-07-06 |
2021-07-28 |
GlaxoSmithKline Biologicals SA |
Immunogenic combination compositions and uses thereof
|
|
EP3456316A1
(en)
*
|
2011-07-06 |
2019-03-20 |
GlaxoSmithKline Biologicals S.A. |
Cationic oil-in-water emulsions
|
|
US20140255472A1
(en)
|
2011-08-31 |
2014-09-11 |
Andrew Geall |
Pegylated liposomes for delivery of immunogen-encoding rna
|
|
EP3384938A1
(en)
|
2011-09-12 |
2018-10-10 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP6113737B2
(ja)
|
2011-10-03 |
2017-04-12 |
モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． |
修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
|
|
AU2012322704B2
(en)
*
|
2011-10-11 |
2017-09-07 |
Novartis Ag |
Recombinant self-replicating polycistronic RNA molecules
|
|
US20140348863A1
(en)
*
|
2011-10-12 |
2014-11-27 |
Alessia Bianchi |
Cmv antigens and uses thereof
|
|
WO2013130161A1
(en)
|
2011-12-14 |
2013-09-06 |
modeRNA Therapeutics |
Methods of responding to a biothreat
|
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
|
CA2859691A1
(en)
|
2011-12-21 |
2013-06-27 |
Moderna Therapeutics, Inc. |
Methods of increasing the viability or longevity of an organ or organ explant
|
|
EP2834259A4
(en)
|
2012-04-02 |
2016-08-24 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES
|
|
HK1206612A1
(en)
|
2012-04-02 |
2016-01-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of secreted proteins
|
|
US9597380B2
(en)
|
2012-11-26 |
2017-03-21 |
Modernatx, Inc. |
Terminally modified RNA
|
|
CN109045294A
(zh)
*
|
2013-01-10 |
2018-12-21 |
思齐乐 |
流感病毒免疫原性组合物及其应用
|
|
US9504747B2
(en)
*
|
2013-03-08 |
2016-11-29 |
Novartis Ag |
Lipids and lipid compositions for the delivery of active agents
|
|
WO2014160243A1
(en)
|
2013-03-14 |
2014-10-02 |
The Trustees Of The University Of Pennsylvania |
Purification and purity assessment of rna molecules synthesized with modified nucleosides
|
|
US10258698B2
(en)
|
2013-03-14 |
2019-04-16 |
Modernatx, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
EP3623361B1
(en)
|
2013-12-19 |
2021-08-18 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
|
EP3350157B1
(en)
|
2015-09-17 |
2022-01-05 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
|
RS63986B1
(sr)
|
2015-10-28 |
2023-03-31 |
Acuitas Therapeutics Inc |
Novi lipidi i lipidne formulacije nanočestica za isporuku nukleinskih kiselina
|
|
CN110114058B
(zh)
|
2016-11-10 |
2023-05-26 |
川斯勒佰尔公司 |
用于递送mrna的改进的基于ice的脂质纳米颗粒制剂
|
|
US11045540B2
(en)
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
|
MX2021005969A
(es)
|
2018-11-21 |
2021-09-14 |
Translate Bio Inc |
Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr nebulizado.
|
|
EP4021407A1
(en)
|
2019-08-30 |
2022-07-06 |
GlaxoSmithKline Biologicals S.A. |
Jet mixing lipid nanoparticle manufacturing process
|
|
DE102019214469A1
(de)
|
2019-09-23 |
2021-03-25 |
Henkel Ag & Co. Kgaa |
Kit und Verfahren zum Färben von keratinischem Material mit Aminosilikon und farbgebender Verbindung
|
|
WO2022137133A1
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Rna vaccine against sars-cov-2 variants
|