JP2015522580A5 - - Google Patents
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- JP2015522580A5 JP2015522580A5 JP2015519154A JP2015519154A JP2015522580A5 JP 2015522580 A5 JP2015522580 A5 JP 2015522580A5 JP 2015519154 A JP2015519154 A JP 2015519154A JP 2015519154 A JP2015519154 A JP 2015519154A JP 2015522580 A5 JP2015522580 A5 JP 2015522580A5
- Authority
- JP
- Japan
- Prior art keywords
- epitope
- polypeptide
- composition
- polypeptide antigen
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 108090000765 processed proteins & peptides Proteins 0.000 claims description 98
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 88
- 229920001184 polypeptide Polymers 0.000 claims description 83
- 239000000203 mixture Substances 0.000 claims description 75
- 239000000427 antigen Substances 0.000 claims description 61
- 102000036639 antigens Human genes 0.000 claims description 61
- 108091007433 antigens Proteins 0.000 claims description 61
- 230000002163 immunogen Effects 0.000 claims description 32
- 241000725303 Human immunodeficiency virus Species 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 21
- 230000037452 priming Effects 0.000 claims description 20
- 125000002091 cationic group Chemical group 0.000 claims description 14
- 239000002502 liposome Substances 0.000 claims description 12
- 239000011859 microparticle Substances 0.000 claims description 12
- 239000004005 microsphere Substances 0.000 claims description 12
- 239000007908 nanoemulsion Substances 0.000 claims description 12
- 239000002077 nanosphere Substances 0.000 claims description 12
- 239000000277 virosome Substances 0.000 claims description 12
- -1 cocriates Substances 0.000 claims description 11
- 230000004927 fusion Effects 0.000 claims description 11
- 239000007764 o/w emulsion Substances 0.000 claims description 10
- 239000007762 w/o emulsion Substances 0.000 claims description 10
- 239000002671 adjuvant Substances 0.000 claims description 8
- 230000003308 immunostimulating effect Effects 0.000 claims description 8
- 241000710929 Alphavirus Species 0.000 claims description 7
- 230000028993 immune response Effects 0.000 claims description 7
- 239000003937 drug carrier Substances 0.000 claims description 6
- 125000003729 nucleotide group Chemical group 0.000 claims description 6
- 239000003981 vehicle Substances 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 5
- 239000000839 emulsion Substances 0.000 claims description 4
- 244000052769 pathogen Species 0.000 claims description 4
- 230000001717 pathogenic effect Effects 0.000 claims description 4
- 239000002356 single layer Substances 0.000 claims description 4
- 230000004936 stimulating effect Effects 0.000 claims description 4
- 238000002255 vaccination Methods 0.000 claims description 3
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 239000002691 unilamellar liposome Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- AWGBKZRMLNVLAF-UHFFFAOYSA-N 3,5-dibromo-n,2-dihydroxybenzamide Chemical compound ONC(=O)C1=CC(Br)=CC(Br)=C1O AWGBKZRMLNVLAF-UHFFFAOYSA-N 0.000 claims 4
- 230000005847 immunogenicity Effects 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 3
- 230000001939 inductive effect Effects 0.000 description 2
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261669010P | 2012-07-06 | 2012-07-06 | |
| US61/669,010 | 2012-07-06 | ||
| US201261698971P | 2012-09-10 | 2012-09-10 | |
| US61/698,971 | 2012-09-10 | ||
| PCT/EP2013/063749 WO2014005958A1 (en) | 2012-07-06 | 2013-06-29 | Immunogenic compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015522580A JP2015522580A (ja) | 2015-08-06 |
| JP2015522580A5 true JP2015522580A5 (enExample) | 2016-08-18 |
Family
ID=48703552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015519154A Pending JP2015522580A (ja) | 2012-07-06 | 2013-06-29 | 免疫学的組成物およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20150140068A1 (enExample) |
| EP (1) | EP2869842A1 (enExample) |
| JP (1) | JP2015522580A (enExample) |
| CN (1) | CN104853770A (enExample) |
| WO (1) | WO2014005958A1 (enExample) |
Families Citing this family (40)
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| US9710606B2 (en) | 2014-10-21 | 2017-07-18 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10366793B2 (en) | 2014-10-21 | 2019-07-30 | uBiome, Inc. | Method and system for characterizing microorganism-related conditions |
| US10311973B2 (en) | 2014-10-21 | 2019-06-04 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10346592B2 (en) | 2014-10-21 | 2019-07-09 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for neurological health issues |
| US10073952B2 (en) | 2014-10-21 | 2018-09-11 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for autoimmune system conditions |
| US10777320B2 (en) | 2014-10-21 | 2020-09-15 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for mental health associated conditions |
| US10388407B2 (en) | 2014-10-21 | 2019-08-20 | uBiome, Inc. | Method and system for characterizing a headache-related condition |
| US9758839B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome functional features |
| US10325685B2 (en) | 2014-10-21 | 2019-06-18 | uBiome, Inc. | Method and system for characterizing diet-related conditions |
| US10265009B2 (en) | 2014-10-21 | 2019-04-23 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for conditions associated with microbiome taxonomic features |
| US9760676B2 (en) | 2014-10-21 | 2017-09-12 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US10381112B2 (en) | 2014-10-21 | 2019-08-13 | uBiome, Inc. | Method and system for characterizing allergy-related conditions associated with microorganisms |
| US10169541B2 (en) | 2014-10-21 | 2019-01-01 | uBiome, Inc. | Method and systems for characterizing skin related conditions |
| US10410749B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cutaneous conditions |
| US10793907B2 (en) | 2014-10-21 | 2020-10-06 | Psomagen, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for endocrine system conditions |
| US9754080B2 (en) | 2014-10-21 | 2017-09-05 | uBiome, Inc. | Method and system for microbiome-derived characterization, diagnostics and therapeutics for cardiovascular disease conditions |
| US11783914B2 (en) | 2014-10-21 | 2023-10-10 | Psomagen, Inc. | Method and system for panel characterizations |
| US10409955B2 (en) | 2014-10-21 | 2019-09-10 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for locomotor system conditions |
| EP3209803A4 (en) | 2014-10-21 | 2018-06-13 | Ubiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics |
| US10789334B2 (en) | 2014-10-21 | 2020-09-29 | Psomagen, Inc. | Method and system for microbial pharmacogenomics |
| US10246753B2 (en) | 2015-04-13 | 2019-04-02 | uBiome, Inc. | Method and system for characterizing mouth-associated conditions |
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| US12491261B2 (en) | 2016-10-26 | 2025-12-09 | Acuitas Therapeutics, Inc. | Lipid nanoparticle formulations |
| CA3062591A1 (en) | 2017-05-08 | 2018-11-15 | Gritstone Oncology, Inc. | Alphavirus neoantigen vectors |
| EP3668833A1 (en) | 2017-08-16 | 2020-06-24 | Acuitas Therapeutics, Inc. | Lipids for use in lipid nanoparticle formulations |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| JP2021505560A (ja) | 2017-12-04 | 2021-02-18 | インターベット インターナショナル ベー． フェー． | イヌライム病ワクチン |
| BR112020011044A2 (pt) * | 2017-12-04 | 2020-11-17 | Intervet International B.V. | vacinação com partículas de replicon e adjuvante de óleo |
| CN118976103A (zh) * | 2017-12-18 | 2024-11-19 | 英特维特国际股份有限公司 | 猪甲型流感病毒疫苗 |
| JP7653013B2 (ja) | 2018-01-04 | 2025-03-28 | アイコニック セラピューティクス リミテッド ライアビリティ カンパニー | 抗組織因子抗体、抗体薬物コンジュゲート、及び関連する方法 |
| CN109200295A (zh) * | 2018-10-08 | 2019-01-15 | 蚌埠医学院 | 一种用于治疗卵巢癌的药物组合物及其制备方法 |
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| MX2023000614A (es) | 2020-07-16 | 2023-02-13 | Acuitas Therapeutics Inc | Lipidos cationicos para usarse en nanoparticulas lipidicas. |
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-
2013
- 2013-06-29 JP JP2015519154A patent/JP2015522580A/ja active Pending
- 2013-06-29 WO PCT/EP2013/063749 patent/WO2014005958A1/en not_active Ceased
- 2013-06-29 EP EP13732536.1A patent/EP2869842A1/en not_active Withdrawn
- 2013-06-29 US US14/410,728 patent/US20150140068A1/en not_active Abandoned
- 2013-06-29 CN CN201380046633.XA patent/CN104853770A/zh active Pending
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