CL2008002322A1 - Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna. - Google Patents

Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.

Info

Publication number
CL2008002322A1
CL2008002322A1 CL2008002322A CL2008002322A CL2008002322A1 CL 2008002322 A1 CL2008002322 A1 CL 2008002322A1 CL 2008002322 A CL2008002322 A CL 2008002322A CL 2008002322 A CL2008002322 A CL 2008002322A CL 2008002322 A1 CL2008002322 A1 CL 2008002322A1
Authority
CL
Chile
Prior art keywords
pharmaceutical formulation
family
arn
sfv
vaccine
Prior art date
Application number
CL2008002322A
Other languages
English (en)
Inventor
Onate Contreras Angel
Andrews Garcia Edilia
Donoso Llanculeo Gabriel
Original Assignee
Univ Concepcion
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Concepcion filed Critical Univ Concepcion
Priority to CL2008002322A priority Critical patent/CL2008002322A1/es
Publication of CL2008002322A1 publication Critical patent/CL2008002322A1/es
Priority to MX2011001429A priority patent/MX2011001429A/es
Priority to PCT/CL2009/000009 priority patent/WO2010015098A1/es
Priority to US13/057,620 priority patent/US20110200667A1/en
Priority to BRPI0917956A priority patent/BRPI0917956A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/098—Brucella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/36011—Togaviridae
    • C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
    • C12N2770/36141—Use of virus, viral particle or viral elements as a vector
    • C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Abstract

Formulación farmacéutica veterinaria que comprende una partícula recombinante de ARN que codifica para una proteína cu/zn superoxidodismutasa de bacterias patógenas de rumiantes y al menos un alfavirus ARN perteneciente a la familia del virus Semliki Forest.
CL2008002322A 2008-08-07 2008-08-07 Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna. CL2008002322A1 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CL2008002322A CL2008002322A1 (es) 2008-08-07 2008-08-07 Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.
MX2011001429A MX2011001429A (es) 2008-08-07 2009-08-07 Formulacion farmaceutica veterinaria que comprende una particula recombinante de arn que codifica para una proteina cu/zn superoxido dismutasa de bacterias patogenas de rumiantes y al menos un alfavirus arn perteneciente a la familia del virus semlik
PCT/CL2009/000009 WO2010015098A1 (es) 2008-08-07 2009-08-07 Formulación farmacéutica veterinaria que comprende una partícula recombinante de arn que codifica para una proteína cu/zn superóxido dismutasa de bacterias patógenas de rumiantes y al menos un alfavirus arn perteneciente a la familia del virus semliki forest
US13/057,620 US20110200667A1 (en) 2008-08-07 2009-08-07 Veterinary pharmaceutical formulacion that comprises an rna recombinant particle that encodes for a cu/zn superoxide dismutase protein of ruminant pathogenic bacteria and at least one rna alphavirus belonging to the semliki forest virus family
BRPI0917956A BRPI0917956A2 (pt) 2008-08-07 2009-08-07 formulação farmacêutica veterinária que inclui uma partícula recombinante de rna que codifica para uma proteína cu/zn superóxido dismutase de bactérias patogênicas de ruminantes e pelo menos um alfavírus rna pertencente à família do vírus semliki forest

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2008002322A CL2008002322A1 (es) 2008-08-07 2008-08-07 Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.

Publications (1)

Publication Number Publication Date
CL2008002322A1 true CL2008002322A1 (es) 2009-06-05

Family

ID=41663260

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008002322A CL2008002322A1 (es) 2008-08-07 2008-08-07 Formulacion farmaceutica veterinaria que comprende un sistema vectorial viral constituido por una particula recombinante de arn que codifica una cu/zn superoxido dismutasa de la bacteria patogena de bovinos brucella abortus, y al menos un alfavirus arn perteneciente a la familia del virus semliki forest (sfv), util como vacuna.

Country Status (5)

Country Link
US (1) US20110200667A1 (es)
BR (1) BRPI0917956A2 (es)
CL (1) CL2008002322A1 (es)
MX (1) MX2011001429A (es)
WO (1) WO2010015098A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3243526T (lt) 2010-07-06 2020-02-10 Glaxosmithkline Biologicals S.A. Rnr pristatymas, skirtas keleto imuninio atsako paleidimui
HRP20221522T1 (hr) 2010-07-06 2023-02-17 Glaxosmithkline Biologicals S.A. Čestice za dostavljanje nalik virionu za samo-replicirajuće rna molekule
US9770463B2 (en) 2010-07-06 2017-09-26 Glaxosmithkline Biologicals Sa Delivery of RNA to different cell types
BR112013000244A2 (pt) 2010-07-06 2016-05-17 Novartis Ag lipossomas com lipídeos apresentando pka vantajoso para administração de rna
SI2591114T1 (sl) 2010-07-06 2016-10-28 Glaxosmithkline Biologicals S.A. Imunizacija velikih sesalcev z majhnimi odmerki RNA
ES2923634T3 (es) 2010-08-31 2022-09-29 Glaxosmithkline Biologicals Sa Liposomas pequeños para la administración de ARN que codifica para inmunógeno
SI3970742T1 (sl) 2010-08-31 2022-08-31 Glaxosmithkline Biologicals S.A. Pegilirani liposomi za dostavo RNA, ki kodira imunogen
EP3520813B1 (en) 2010-10-11 2023-04-19 GlaxoSmithKline Biologicals S.A. Antigen delivery platforms
CA2840989A1 (en) 2011-07-06 2013-01-10 Novartis Ag Immunogenic combination compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824310A (en) * 1991-10-22 1998-10-20 The United States Of America As Represented By The Department Of Health And Human Services Lipopplysaccharide conjugate vaccines
US6264952B1 (en) * 1993-11-05 2001-07-24 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for protecting a mammalian host against infection by Brucella
SE9401091D0 (sv) * 1994-03-31 1994-03-31 Bioption Ab Alphavirus cDNA vectors

Also Published As

Publication number Publication date
MX2011001429A (es) 2011-03-29
BRPI0917956A2 (pt) 2015-11-10
WO2010015098A1 (es) 2010-02-11
US20110200667A1 (en) 2011-08-18

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