|
GB864145A
(en)
*
|
1959-06-02 |
1961-03-29 |
Thomae Gmbh Dr K |
Novel purines and a process for their manufacture
|
|
US3016378A
(en)
*
|
1959-07-01 |
1962-01-09 |
Thomae Gmbh Dr K |
Amino-substituted purine derivatives
|
|
JPS6041077B2
(ja)
|
1976-09-06 |
1985-09-13 |
喜徳 喜谷 |
１，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
|
|
US4323581A
(en)
|
1978-07-31 |
1982-04-06 |
Johnson & Johnson |
Method of treating carcinogenesis
|
|
IL73534A
(en)
|
1983-11-18 |
1990-12-23 |
Riker Laboratories Inc |
1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
|
|
WO1988007045A1
(fr)
|
1987-03-09 |
1988-09-22 |
Kyowa Hakko Kogyo Co., Ltd. |
Derives de la substance physiologiquement active k-252
|
|
US4904768A
(en)
|
1987-08-04 |
1990-02-27 |
Bristol-Myers Company |
Epipodophyllotoxin glucoside 4'-phosphate derivatives
|
|
EP0383919A4
(en)
|
1988-02-04 |
1992-08-05 |
Kyowa Hakko Kogyo Co., Ltd. |
Staurosporin derivatives
|
|
US5238944A
(en)
|
1988-12-15 |
1993-08-24 |
Riker Laboratories, Inc. |
Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
|
|
US4929624A
(en)
|
1989-03-23 |
1990-05-29 |
Minnesota Mining And Manufacturing Company |
Olefinic 1H-imidazo(4,5-c)quinolin-4-amines
|
|
US5389640A
(en)
|
1991-03-01 |
1995-02-14 |
Minnesota Mining And Manufacturing Company |
1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
US6410010B1
(en)
|
1992-10-13 |
2002-06-25 |
Board Of Regents, The University Of Texas System |
Recombinant P53 adenovirus compositions
|
|
US5268376A
(en)
|
1991-09-04 |
1993-12-07 |
Minnesota Mining And Manufacturing Company |
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
|
|
EP0540185A1
(en)
|
1991-10-10 |
1993-05-05 |
Schering Corporation |
4'-(N-substituted-N-oxide)staurosporine derivatives
|
|
US5266575A
(en)
|
1991-11-06 |
1993-11-30 |
Minnesota Mining And Manufacturing Company |
2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines
|
|
AU3064992A
(en)
|
1991-11-08 |
1993-06-07 |
University Of Southern California |
Compositions containing k-252 compounds for potentiation of neurotrophin activity
|
|
AU661533B2
(en)
|
1992-01-20 |
1995-07-27 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US5948898A
(en)
|
1992-03-16 |
1999-09-07 |
Isis Pharmaceuticals, Inc. |
Methoxyethoxy oligonucleotides for modulation of protein kinase C expression
|
|
PT633886E
(pt)
|
1992-04-03 |
2001-03-30 |
Upjohn Co |
Aminas biciclicas-heterociclicas farmaceuticamente activas
|
|
US5756494A
(en)
|
1992-07-24 |
1998-05-26 |
Cephalon, Inc. |
Protein kinase inhibitors for treatment of neurological disorders
|
|
US5621100A
(en)
|
1992-07-24 |
1997-04-15 |
Cephalon, Inc. |
K-252a derivatives for treatment of neurological disorders
|
|
ES2225824T3
(es)
|
1992-08-31 |
2005-03-16 |
Ludwig Institute For Cancer Research |
Nonapeptido aislado derivado del gen mage-3 y presentado por hla-a1, y sus usos.
|
|
DE69331228T4
(de)
|
1992-09-21 |
2002-09-05 |
Kyowa Hakko Kogyo Co., Ltd. |
Heilmittel für thrombozytopenia
|
|
KR100335584B1
(ko)
|
1992-10-28 |
2002-11-29 |
제넨테크, 인코포레이티드 |
혈관내피세포성장인자에대한길항제
|
|
US5395937A
(en)
|
1993-01-29 |
1995-03-07 |
Minnesota Mining And Manufacturing Company |
Process for preparing quinoline amines
|
|
US5352784A
(en)
|
1993-07-15 |
1994-10-04 |
Minnesota Mining And Manufacturing Company |
Fused cycloalkylimidazopyridines
|
|
DK0708772T3
(da)
|
1993-07-15 |
2000-09-18 |
Minnesota Mining & Mfg |
Imidazo[4,5,-c]pyridin-4-aminer
|
|
US5478932A
(en)
|
1993-12-02 |
1995-12-26 |
The Board Of Trustees Of The University Of Illinois |
Ecteinascidins
|
|
EP1449529B1
(en)
|
1993-12-23 |
2010-01-27 |
Eli Lilly And Company |
Protein Kinase C Inhibitors
|
|
US5587459A
(en)
|
1994-08-19 |
1996-12-24 |
Regents Of The University Of Minnesota |
Immunoconjugates comprising tyrosine kinase inhibitors
|
|
US6083903A
(en)
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
|
US5482936A
(en)
|
1995-01-12 |
1996-01-09 |
Minnesota Mining And Manufacturing Company |
Imidazo[4,5-C]quinoline amines
|
|
ATE446955T1
(de)
|
1995-03-30 |
2009-11-15 |
Pfizer Prod Inc |
Chinazolinone derivate
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US6331555B1
(en)
|
1995-06-01 |
2001-12-18 |
University Of California |
Treatment of platelet derived growth factor related disorders such as cancers
|
|
US5747498A
(en)
|
1996-05-28 |
1998-05-05 |
Pfizer Inc. |
Alkynyl and azido-substituted 4-anilinoquinazolines
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
WO1997007081A2
(en)
|
1995-08-11 |
1997-02-27 |
Yale University |
Glycosylated indolocarbazole synthesis
|
|
FR2741881B1
(fr)
|
1995-12-01 |
1999-07-30 |
Centre Nat Rech Scient |
Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
|
|
DE69635966T2
(de)
|
1995-12-08 |
2006-11-30 |
Janssen Pharmaceutica N.V. |
(Imidazol-5-yl)Methyl-2-Chinolinonderivate als Farnesyl Protein transferase Inhibitoren
|
|
KR100447918B1
(ko)
|
1996-07-25 |
2005-09-28 |
동아제약주식회사 |
대장을포함한위장관보호작용을갖는플라본및플라바논화합물
|
|
CN1189562C
(zh)
|
1996-08-02 |
2005-02-16 |
吉倪塞思技术公司 |
针对核糖核苷酸还原酶r1和r2组分的抗肿瘤反义序列
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
US6126965A
(en)
|
1997-03-21 |
2000-10-03 |
Georgetown University School Of Medicine |
Liposomes containing oligonucleotides
|
|
EP1017394B1
(en)
|
1997-07-12 |
2005-12-07 |
Cancer Research Technology Limited |
Cyclin dependent kinase inhibiting purine derivatives
|
|
RS49779B
(sr)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
|
|
KR100743287B1
(ko)
|
1998-05-29 |
2007-07-26 |
수젠, 인크. |
피롤기로 치환된 2-인돌리논 단백질 인산화 효소 억제제
|
|
US20030083242A1
(en)
|
1998-11-06 |
2003-05-01 |
Alphonse Galdes |
Methods and compositions for treating or preventing peripheral neuropathies
|
|
AR024464A1
(es)
|
1999-06-25 |
2002-10-02 |
Genentech Inc |
Anticuerpos anti-erbb2 humanizados.
|
|
AU6014900A
(en)
|
1999-07-13 |
2001-01-30 |
Kyowa Hakko Kogyo Co. Ltd. |
Staurosporin derivatives
|
|
PT1244647E
(pt)
|
1999-11-05 |
2006-10-31 |
Astrazeneca Ab |
Derivados de quinazolina como inibidores de vegf
|
|
HRP20020751B1
(hr)
|
2000-02-15 |
2011-01-31 |
Sugen |
Pirolom supstituirani 2-indolinoni kao inhibitori protein kinaze
|
|
EP1274718B1
(en)
|
2000-04-12 |
2006-10-18 |
Genaera Corporation |
A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group
|
|
CA2413134C
(en)
|
2000-06-30 |
2010-05-11 |
Glaxo Group Limited |
Quinazoline ditosylate salt compounds
|
|
BRPI0113757B8
(pt)
|
2000-09-11 |
2017-11-07 |
Chiron Corp |
derivados de quinolinona como inibidores de tirosina quinase
|
|
US6677450B2
(en)
|
2000-10-06 |
2004-01-13 |
Bristol-Myers Squibb Company |
Topoisomerase inhibitors
|
|
ATE325865T1
(de)
|
2001-01-16 |
2006-06-15 |
Regeneron Pharma |
Isolierung von sezernierte proteine exprimierenden zellen
|
|
WO2002062826A1
(fr)
|
2001-02-07 |
2002-08-15 |
Vadim Viktorovich Novikov |
Procede de fabrication des peptides
|
|
EP1404689A1
(en)
|
2001-07-02 |
2004-04-07 |
Debiopharm S.A. |
Oxaliplatin active substance with a very low content of oxalic acid
|
|
KR100484504B1
(ko)
|
2001-09-18 |
2005-04-20 |
학교법인 포항공과대학교 |
쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물
|
|
US20030134846A1
(en)
|
2001-10-09 |
2003-07-17 |
Schering Corporation |
Treatment of trypanosoma brucei with farnesyl protein transferase inhibitors
|
|
WO2004078163A2
(en)
|
2003-02-28 |
2004-09-16 |
Transform Pharmaceuticals, Inc. |
Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
|
|
US6927036B2
(en)
|
2002-02-19 |
2005-08-09 |
Xero Port, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
MXPA04009541A
(es)
|
2002-03-29 |
2005-01-25 |
Chiron Corp |
Benzazoles sustituidos y uso de los mismos como inhibidores de cinasa raf.
|
|
US6727272B1
(en)
|
2002-07-15 |
2004-04-27 |
Unitech Pharmaceuticals, Inc. |
Leflunomide analogs for treating rheumatoid arthritis
|
|
US7148342B2
(en)
|
2002-07-24 |
2006-12-12 |
The Trustees Of The University Of Pennyslvania |
Compositions and methods for sirna inhibition of angiogenesis
|
|
CA2511646A1
(en)
|
2002-12-27 |
2004-07-22 |
Chiron Corporation |
Thiosemicarbazones as anti-virals and immunopotentiators
|
|
WO2004064759A2
(en)
|
2003-01-21 |
2004-08-05 |
Chiron Corporation |
Use of tryptanthrin compounds for immune potentiation
|
|
WO2004087153A2
(en)
|
2003-03-28 |
2004-10-14 |
Chiron Corporation |
Use of organic compounds for immunopotentiation
|
|
WO2006128172A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating b cell regulated autoimmune disorders
|
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
|
WO2010002954A1
(en)
*
|
2008-07-02 |
2010-01-07 |
Wyeth |
(2-aryl-7h-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine compounds, their use as mtor kinase and pi3 kinase inhibitors, and their syntheses
|
|
CA2740389A1
(en)
|
2008-10-15 |
2010-05-20 |
Gilead Sciences, Inc. |
3-hydroquinazolin-4-one derivatives for use as stearoyl coa desaturase inhibitors
|
|
KR20110098908A
(ko)
*
|
2008-11-11 |
2011-09-02 |
엑스커버리 홀딩 컴퍼니 엘엘씨 |
ＰＩ3Ｋ/ｍＴＯＲ 키나제 억제제
|
|
AR077974A1
(es)
|
2009-08-28 |
2011-10-05 |
Takeda Pharmaceutical |
Compuestos de hexahidrooxazinopterina para uso como inhibidores de mtor
|
|
ES2567168T3
(es)
|
2009-11-12 |
2016-04-20 |
F. Hoffmann-La Roche Ag |
Compuestos purina y pirazolopirimidina N7-sustituidos, composiciones y métodos de utilización
|
|
WO2011058027A2
(en)
|
2009-11-12 |
2011-05-19 |
F. Hoffmann-La Roche Ag |
N-9-substituted purine compounds, compositions and methods of use
|
|
WO2011078795A1
(en)
|
2009-12-21 |
2011-06-30 |
S*Bio Pte Ltd |
Bridged morpholino substituted purines
|
|
AR083267A1
(es)
|
2010-10-04 |
2013-02-13 |
Novartis Ag |
Combinaciones farmaceuticas
|
|
WO2012104776A1
(en)
|
2011-01-31 |
2012-08-09 |
Novartis Ag |
Novel heterocyclic derivatives
|
|
WO2013016305A2
(en)
|
2011-07-22 |
2013-01-31 |
Nvidia Corporation |
Component analysis systems and methods
|
|
SG11201401716XA
(en)
|
2011-10-28 |
2014-05-29 |
Novartis Ag |
Novel purine derivatives and their use in the treatment of disease
|