|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
US8791112B2
(en)
|
2011-03-30 |
2014-07-29 |
Arrien Pharmaceuticals Llc |
Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors
|
|
GB201204985D0
(en)
|
2012-03-21 |
2012-05-02 |
Genentech Inc |
Compounds
|
|
US9187484B2
(en)
|
2012-05-02 |
2015-11-17 |
Southern Research Institute |
Triazolopyridazine compounds, use as inhibitors of the kinase LRRK2, and methods for preparation thereof
|
|
CN102675310B
(zh)
*
|
2012-05-09 |
2014-12-24 |
林辉 |
制备吡唑并芳杂环化合物的方法
|
|
LT3495367T
(lt)
|
2012-06-13 |
2021-02-25 |
Incyte Holdings Corporation |
Pakeistieji tricikliniai junginiai, kaip fgfr inhibitoriai
|
|
MD20140130A2
(ro)
*
|
2012-06-29 |
2015-04-30 |
Pfizer Inc. |
4-(amino-substituite)-7H-pirolo[2,3-d]pirimidine noi ca inhibitori de LRRK2
|
|
WO2014026125A1
(en)
|
2012-08-10 |
2014-02-13 |
Incyte Corporation |
Pyrazine derivatives as fgfr inhibitors
|
|
EP2917216B1
(en)
|
2012-11-08 |
2017-10-18 |
Pfizer Inc |
Heteroaromatic compounds as dopamine d1 ligands
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
WO2014134772A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
US9440952B2
(en)
|
2013-03-04 |
2016-09-13 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134776A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134774A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
PL2970333T3
(pl)
*
|
2013-03-15 |
2017-12-29 |
Oncodesign S.A. |
Makrocykliczne inhibitory kinazy LRRK2
|
|
US20140288043A1
(en)
*
|
2013-03-19 |
2014-09-25 |
Genentech, Inc. |
Pyrazolopyridine compounds
|
|
TW201533043A
(zh)
*
|
2013-04-18 |
2015-09-01 |
Lundbeck & Co As H |
作爲ｌｒｒｋ２抑制劑的芳基吡咯并吡啶衍生化合物
|
|
LT2986610T
(lt)
|
2013-04-19 |
2018-04-10 |
Incyte Holdings Corporation |
Bicikliniai heterociklai, kaip fgfr inhibitoriai
|
|
US9718818B2
(en)
|
2013-08-22 |
2017-08-01 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2015092592A1
(en)
|
2013-12-17 |
2015-06-25 |
Pfizer Inc. |
Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
|
|
CN103819396B
(zh)
*
|
2014-02-26 |
2016-06-15 |
四川大学 |
一种手性的1-（3,5-二氯吡啶-4-基）-乙醇的合成方法
|
|
WO2015162518A1
(en)
|
2014-04-25 |
2015-10-29 |
Pfizer Inc. |
Heteroaromatic compounds and their use as dopamine d1 ligands
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
SG11201706287PA
(en)
|
2015-02-20 |
2017-09-28 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
KR20180030201A
(ko)
*
|
2015-07-23 |
2018-03-21 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
화합물
|
|
CN108137586B
(zh)
|
2015-09-14 |
2021-04-13 |
辉瑞大药厂 |
作为LRRK2抑制剂的新颖咪唑并[4,5-c]喹啉和咪唑并[4,5-c][1,5]萘啶衍生物
|
|
WO2017087905A1
(en)
|
2015-11-20 |
2017-05-26 |
Denali Therapeutics Inc. |
Compound, compositions, and methods
|
|
CN108934162A
(zh)
|
2015-12-16 |
2018-12-04 |
南方研究所 |
吡咯并嘧啶化合物、作为激酶lrrk2抑制剂的用途及其制备方法
|
|
US11028080B2
(en)
|
2016-03-11 |
2021-06-08 |
Denali Therapeutics Inc. |
Substituted pyrimidines as LRKK2 inhibitors
|
|
IL299415B2
(en)
|
2016-06-16 |
2025-09-01 |
Denali Therapeutics Inc |
Pyrimidine-2-ylamino-1H-pyrazoles as LRRK2 inhibitors for use in the treatment of neurodegenerative disorders
|
|
IL292977A
(en)
*
|
2016-09-09 |
2022-07-01 |
Incyte Corp |
Pyrazolopyridine derivatives as modulators of hpk1 and their use in cancer therapy
|
|
US20180072718A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
|
US10280164B2
(en)
|
2016-09-09 |
2019-05-07 |
Incyte Corporation |
Pyrazolopyridone compounds and uses thereof
|
|
US10040211B2
(en)
|
2016-12-09 |
2018-08-07 |
Bettcher Industries, Inc. |
Power operated rotary knife
|
|
WO2018152220A1
(en)
|
2017-02-15 |
2018-08-23 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
|
SG11201908234WA
(en)
*
|
2017-02-24 |
2019-10-30 |
Daegu Gyeongbuk Medical Innovation Found |
Pharmaceutical composition comprising compound capable of penetrating blood-brain barrier as effective ingredient for preventing or treating brain cancer
|
|
WO2018163030A1
(en)
|
2017-03-10 |
2018-09-13 |
Pfizer Inc. |
Cyclic substituted imidazo[4,5-c]quinoline derivatives
|
|
WO2018163066A1
(en)
|
2017-03-10 |
2018-09-13 |
Pfizer Inc. |
Novel imidazo[4,5-c]quinoline derivatives as lrrk2 inhibitors
|
|
AU2018269947B2
(en)
*
|
2017-05-15 |
2021-10-14 |
The Regents Of The University Of Michigan |
Pyrrolo(2,3-c)pyridines and related analogs as LSD-1 inhibitors
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US10722495B2
(en)
|
2017-09-08 |
2020-07-28 |
Incyte Corporation |
Cyanoindazole compounds and uses thereof
|
|
US10752635B2
(en)
|
2018-02-20 |
2020-08-25 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
JP7526673B2
(ja)
|
2018-02-20 |
2024-08-01 |
インサイト・コーポレイション |
がんを治療するためのｈｐｋ１阻害剤としてのｎ－（フェニル）－２－（フェニル）ピリミジン－４－カルボキサミド誘導体及び関連化合物
|
|
US10745388B2
(en)
|
2018-02-20 |
2020-08-18 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
US11299473B2
(en)
|
2018-04-13 |
2022-04-12 |
Incyte Corporation |
Benzimidazole and indole compounds and uses thereof
|
|
MX2020011718A
(es)
|
2018-05-04 |
2021-02-15 |
Incyte Corp |
Formas solidas de un inhibidor de receptores del factor de crecimiento de fibroblastos (fgfr) y procesos para prepararlas.
|
|
ES3061844T3
(en)
|
2018-05-04 |
2026-04-07 |
Incyte Corp |
Salts of an fgfr inhibitor
|
|
ES2738911A1
(es)
|
2018-07-25 |
2020-01-27 |
Consejo Superior Investigacion |
Procedimiento para depositar elementos sobre un sustrato de interes y dispositivo
|
|
US10899755B2
(en)
|
2018-08-08 |
2021-01-26 |
Incyte Corporation |
Benzothiazole compounds and uses thereof
|
|
ES2744304B2
(es)
|
2018-08-24 |
2020-06-22 |
Consejo Superior Investigacion |
Compuestos inhibidores de LRRK2 y su uso para el tratamiento de enfermedades neurodegenerativas
|
|
ES2973117T3
(es)
|
2018-09-25 |
2024-06-18 |
Incyte Corp |
Compuestos de pirazolo[4,3-d]pirimidina como moduladores de ALK2 y/o FGFR
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
KR20220059480A
(ko)
|
2019-08-06 |
2022-05-10 |
인사이트 코포레이션 |
고체 형태의 hpk1 억제제
|
|
US12122767B2
(en)
|
2019-10-01 |
2024-10-22 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
TWI891666B
(zh)
|
2019-10-14 |
2025-08-01 |
美商英塞特公司 |
作為ｆｇｆｒ抑制劑之雙環雜環
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021113462A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Derivatives of an fgfr inhibitor
|
|
CA3163875A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
JP2024512501A
(ja)
|
2021-03-19 |
2024-03-19 |
アルヴィナス・オペレーションズ・インコーポレイテッド |
インダゾール系化合物及び関連使用方法
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含ｆｇｆｒ抑制劑及ｎｅｃｔｉｎ－４靶向劑之組合療法
|
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
JP2024522189A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Ｆｇｆｒ阻害剤としての三環式ヘテロ環
|
|
WO2023076404A1
(en)
|
2021-10-27 |
2023-05-04 |
Aria Pharmaceuticals, Inc. |
Methods for treating systemic lupus erythematosus
|
|
AU2024352092A1
(en)
|
2023-09-28 |
2026-04-09 |
Arvinas Operations, Inc. |
Benzimidazole and benzimidazolone based protac compounds for the targeted degradation of leucine rich repeat kinase 2 (lrrk2)
|
|
WO2025248032A1
(en)
|
2024-05-31 |
2025-12-04 |
Syngenta Crop Protection Ag |
Pesticidally active indazole compounds
|