|
US8754114B2
(en)
|
2010-12-22 |
2014-06-17 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
|
|
US8791112B2
(en)
|
2011-03-30 |
2014-07-29 |
Arrien Pharmaceuticals Llc |
Substituted 5-(pyrazin-2-yl)-1H-pyrazolo [3, 4-B] pyridine and pyrazolo [3, 4-B] pyridine derivatives as protein kinase inhibitors
|
|
GB201204985D0
(en)
|
2012-03-21 |
2012-05-02 |
Genentech Inc |
Compounds
|
|
EP2844660B1
(en)
*
|
2012-05-02 |
2017-11-01 |
Southern Research Institute |
Triazolopyridazine compounds, use as inhibitors of the kinase lrrk2, and methods for preparation thereof
|
|
CN102675310B
(zh)
*
|
2012-05-09 |
2014-12-24 |
林辉 |
制备吡唑并芳杂环化合物的方法
|
|
EP3176170B1
(en)
|
2012-06-13 |
2018-11-14 |
Incyte Holdings Corporation |
Substituted tricyclic compounds as fgfr inhibitors
|
|
CA2878054C
(en)
|
2012-06-29 |
2018-09-11 |
Pfizer Inc. |
Novel 4-(substituted-amino)-7h-pyrrolo[2,3-d]pyrimidines as lrrk2 inhibitors
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
GEP201606598B
(en)
|
2012-11-08 |
2017-01-10 |
Pfizer |
Heteroaromatic compounds as dopamine d1 ligands
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
WO2014134772A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134774A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014137728A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2014134776A1
(en)
|
2013-03-04 |
2014-09-12 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
SG11201506357RA
(en)
*
|
2013-03-15 |
2015-09-29 |
Ipsen Pharma Sas |
Macrocyclic lrrk2 kinase inhibitors
|
|
US20140288043A1
(en)
*
|
2013-03-19 |
2014-09-25 |
Genentech, Inc. |
Pyrazolopyridine compounds
|
|
TW201533043A
(zh)
*
|
2013-04-18 |
2015-09-01 |
Lundbeck & Co As H |
作爲ｌｒｒｋ２抑制劑的芳基吡咯并吡啶衍生化合物
|
|
SG10201708520YA
(en)
|
2013-04-19 |
2017-12-28 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
EP3035800B1
(en)
*
|
2013-08-22 |
2019-10-09 |
Merck Sharp & Dohme Corp. |
Compounds inhibiting leucine-rich repeat kinase enzyme activity
|
|
WO2015092592A1
(en)
|
2013-12-17 |
2015-06-25 |
Pfizer Inc. |
Novel 3,4-disubstituted-1h-pyrrolo[2,3-b]pyridines and 4,5-disubstituted-7h-pyrrolo[2,3-c]pyridazines as lrrk2 inhibitors
|
|
CN103819396B
(zh)
*
|
2014-02-26 |
2016-06-15 |
四川大学 |
一种手性的1-（3,5-二氯吡啶-4-基）-乙醇的合成方法
|
|
WO2015162518A1
(en)
|
2014-04-25 |
2015-10-29 |
Pfizer Inc. |
Heteroaromatic compounds and their use as dopamine d1 ligands
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
MX373169B
(es)
|
2015-02-20 |
2020-04-24 |
Incyte Holdings Corp |
Heterociclos bicíclicos como inhibidores de receptores del factor de crecimiento fibroblástico (fgfr).
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
US10975081B2
(en)
*
|
2015-07-23 |
2021-04-13 |
Glaxosmithkline Intellectual Property Development Limited |
Substituted fused pyrazole compounds and their use as LRRK2 inhibitors
|
|
AU2016322813B2
(en)
|
2015-09-14 |
2021-04-01 |
Pfizer Inc. |
Novel imidazo (4,5-c) quinoline and imidazo (4,5-c)(1,5) naphthyridine derivatives as LRRK2 inhibitors
|
|
US11214565B2
(en)
|
2015-11-20 |
2022-01-04 |
Denali Therapeutics Inc. |
Compound, compositions, and methods
|
|
WO2017106771A1
(en)
|
2015-12-16 |
2017-06-22 |
Southern Research Institute |
Pyrrolopyrimidine compounds, use as inhibitors of the kinase lrrk2, and methods for preparation thereof
|
|
US11028080B2
(en)
|
2016-03-11 |
2021-06-08 |
Denali Therapeutics Inc. |
Substituted pyrimidines as LRKK2 inhibitors
|
|
JOP20180113B1
(ar)
|
2016-06-16 |
2022-03-14 |
Denali Therapeutics Inc |
مركبات بيريميدين -2-يل امينو -h1- بيرازول كمثبطات lrrk2 للاستخدام في علاج اضطرابات تنكسية عصبية
|
|
WO2018049214A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
|
WO2018049191A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridone derivatives as hpk1 modulators and uses thereof for the treatment of cancer
|
|
CN109923114B
(zh)
|
2016-09-09 |
2022-11-01 |
因赛特公司 |
作为hpk1调节剂的吡唑并吡啶衍生物和其用于治疗癌症的用途
|
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
|
US10040211B2
(en)
|
2016-12-09 |
2018-08-07 |
Bettcher Industries, Inc. |
Power operated rotary knife
|
|
US20180228786A1
(en)
|
2017-02-15 |
2018-08-16 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
|
JP6728503B2
(ja)
|
2017-02-24 |
2020-07-22 |
テグ−キョンプク メディカル イノベーション ファウンデーション |
血液脳関門を通過することができる化合物を有効成分として含有する脳腫瘍の予防または治療用薬学的組成物
|
|
CA3056027A1
(en)
|
2017-03-10 |
2018-09-13 |
Pfizer Inc. |
Cyclic substituted imidazo[4,5-c]quinoline derivatives
|
|
CN111051304B
(zh)
|
2017-03-10 |
2022-12-27 |
辉瑞大药厂 |
作为LRRK2抑制剂的咪唑并[4,5-c]喹啉衍生物
|
|
US11168082B2
(en)
*
|
2017-05-15 |
2021-11-09 |
The Regents Of The University Of Michigan |
Pyrrolo[2,3-C]pyridines and related analogs as LSD-1 inhibitors
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US10722495B2
(en)
|
2017-09-08 |
2020-07-28 |
Incyte Corporation |
Cyanoindazole compounds and uses thereof
|
|
US10752635B2
(en)
|
2018-02-20 |
2020-08-25 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
US10745388B2
(en)
|
2018-02-20 |
2020-08-18 |
Incyte Corporation |
Indazole compounds and uses thereof
|
|
KR20200133747A
(ko)
|
2018-02-20 |
2020-11-30 |
인사이트 코포레이션 |
암을 치료하기 위한 hpk1 억제제로서의 n-(페닐)-2-(페닐)피리미딘-4-카복스아미드 유도체 및 관련 화합물
|
|
US11299473B2
(en)
|
2018-04-13 |
2022-04-12 |
Incyte Corporation |
Benzimidazole and indole compounds and uses thereof
|
|
BR112020022373A2
(pt)
|
2018-05-04 |
2021-02-02 |
Incyte Corporation |
sais de um inibidor de fgfr
|
|
CR20240498A
(es)
|
2018-05-04 |
2025-01-08 |
Incyte Corp |
FORMAS SÓLIDAS DE UN INHIBIDOR DE FGFR Y PROCESOS PARA PREPARARLAS (Divisional EXP. 2020-0590)
|
|
ES2738911A1
(es)
|
2018-07-25 |
2020-01-27 |
Consejo Superior Investigacion |
Procedimiento para depositar elementos sobre un sustrato de interes y dispositivo
|
|
US10899755B2
(en)
|
2018-08-08 |
2021-01-26 |
Incyte Corporation |
Benzothiazole compounds and uses thereof
|
|
ES2744304B2
(es)
|
2018-08-24 |
2020-06-22 |
Consejo Superior Investigacion |
Compuestos inhibidores de LRRK2 y su uso para el tratamiento de enfermedades neurodegenerativas
|
|
WO2020068729A1
(en)
|
2018-09-25 |
2020-04-02 |
Incyte Corporation |
Pyrazolo[4,3-d]pyrimidine compounds as alk2 abd/or fgfr modulators
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021026180A1
(en)
|
2019-08-06 |
2021-02-11 |
Incyte Corporation |
Solid forms of an hpk1 inhibitor
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
JOP20220083A1
(ar)
|
2019-10-14 |
2023-01-30 |
Incyte Corp |
حلقات غير متجانسة ثنائية الحلقة كمثبطات لـ fgfr
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
PE20221504A1
(es)
|
2019-12-04 |
2022-09-30 |
Incyte Corp |
Derivados de un inhibidor de fgfr
|
|
EP4069696A1
(en)
|
2019-12-04 |
2022-10-12 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US12012409B2
(en)
|
2020-01-15 |
2024-06-18 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
JP2024522188A
(ja)
|
2021-06-09 |
2024-06-11 |
インサイト・コーポレイション |
Ｆｇｆｒ阻害剤としての三環式ヘテロ環
|
|
EP4352059A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
WO2023076404A1
(en)
|
2021-10-27 |
2023-05-04 |
Aria Pharmaceuticals, Inc. |
Methods for treating systemic lupus erythematosus
|
|
WO2025248032A1
(en)
|
2024-05-31 |
2025-12-04 |
Syngenta Crop Protection Ag |
Pesticidally active indazole compounds
|