JP2013542747A5 - - Google Patents

Download PDF

Info

Publication number
JP2013542747A5
JP2013542747A5 JP2013540104A JP2013540104A JP2013542747A5 JP 2013542747 A5 JP2013542747 A5 JP 2013542747A5 JP 2013540104 A JP2013540104 A JP 2013540104A JP 2013540104 A JP2013540104 A JP 2013540104A JP 2013542747 A5 JP2013542747 A5 JP 2013542747A5
Authority
JP
Japan
Prior art keywords
genetically modified
yeast cell
modified yeast
cell according
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013540104A
Other languages
English (en)
Japanese (ja)
Other versions
JP6061862B2 (ja
JP2013542747A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/061717 external-priority patent/WO2012074818A2/en
Publication of JP2013542747A publication Critical patent/JP2013542747A/ja
Publication of JP2013542747A5 publication Critical patent/JP2013542747A5/ja
Application granted granted Critical
Publication of JP6061862B2 publication Critical patent/JP6061862B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2013540104A 2010-11-22 2011-11-21 3‐ヒドロキシプロピオン酸生産用の組成物及び方法 Active JP6061862B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US41619910P 2010-11-22 2010-11-22
US61/416,199 2010-11-22
US201161535181P 2011-09-15 2011-09-15
US61/535,181 2011-09-15
PCT/US2011/061717 WO2012074818A2 (en) 2010-11-22 2011-11-21 Compositions and methods for 3-hydroxypropionic acid production

Publications (3)

Publication Number Publication Date
JP2013542747A JP2013542747A (ja) 2013-11-28
JP2013542747A5 true JP2013542747A5 (https=) 2015-01-15
JP6061862B2 JP6061862B2 (ja) 2017-01-18

Family

ID=45099210

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013540104A Active JP6061862B2 (ja) 2010-11-22 2011-11-21 3‐ヒドロキシプロピオン酸生産用の組成物及び方法

Country Status (11)

Country Link
US (7) US9090918B2 (https=)
EP (2) EP3287519B1 (https=)
JP (1) JP6061862B2 (https=)
KR (1) KR20130119945A (https=)
CN (2) CN107828671B (https=)
AU (1) AU2011336923B2 (https=)
BR (1) BR112013012630B1 (https=)
CA (1) CA2818499A1 (https=)
MX (1) MX2013005654A (https=)
WO (1) WO2012074818A2 (https=)
ZA (1) ZA201303544B (https=)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0709607B1 (pt) 2006-03-13 2018-05-08 Cargill Inc cédulas de levedura tendo via rompida de diidroxi acetona fosfato para glicerol e processo de fermentação"
BR112013003003A2 (pt) 2010-08-06 2016-06-14 Mascoma Corp produção de produtos malonil-coa derivados através de rotas anaeróbicas
CN107828671B (zh) * 2010-11-22 2022-03-08 卡吉尔公司 用于生产3-羟基丙酸的组合物和方法
ES2645680T3 (es) * 2010-11-22 2017-12-07 Cargill, Incorporated Células de levadura y proceso para convertir acetaldehído en etanol
WO2013003608A1 (en) * 2011-06-28 2013-01-03 Brookhaven Science Associates, Llc Modified plants with increased oil content
US9493790B2 (en) * 2011-08-24 2016-11-15 Novozymes, Inc. Methods for producing multiple recombinant polypeptides in a filamentous fungal host cell
US8728788B1 (en) 2011-09-30 2014-05-20 Novozymes A/S Dehydrogenase variants and polynucleotides encoding same
CN107586732A (zh) * 2012-03-06 2018-01-16 利戈斯股份有限公司 用于产生丙二酸的重组宿主细胞
US9994878B2 (en) * 2012-05-30 2018-06-12 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
SG11201501013PA (en) 2012-08-10 2015-04-29 Opx Biotechnologies Inc Microorganisms and methods for the production of fatty acids and fatty acid derived products
CA2888093A1 (en) * 2012-10-11 2014-04-17 Technical University Of Denmark Genetically engineered yeast
CN105209626B (zh) * 2012-11-30 2019-09-03 诺维信股份有限公司 通过重组酵母生产3-羟基丙酸
AU2014244216A1 (en) * 2013-03-14 2015-09-24 E.I. Du Pont De Nemours And Company Glycerol 3- phosphate dehydrogenase for butanol production
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US10442749B2 (en) 2013-03-15 2019-10-15 Cargill, Incorporated Recovery of 3-hydroxypropionic acid
US20150044746A1 (en) * 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction
EP3008179A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark 3hp tolerance
EP3008178A1 (en) 2013-06-14 2016-04-20 Technical University of Denmark Microbial production of 3-hydroxypropionic acid
US9556443B2 (en) 2013-07-19 2017-01-31 Samsung Electronics Co., Ltd. Yeast cell with inactivated NADH dehydrogenase and method of producing lactate using the yeast cell
US11408013B2 (en) 2013-07-19 2022-08-09 Cargill, Incorporated Microorganisms and methods for the production of fatty acids and fatty acid derived products
CN106795483A (zh) 2013-07-19 2017-05-31 嘉吉公司 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法
CN105431520A (zh) * 2013-07-31 2016-03-23 诺维信公司 利用表达昆虫天冬氨酸1-脱羧酶的重组酵母的3-羟基丙酸生产
WO2015031504A1 (en) * 2013-08-27 2015-03-05 The Regents Of The University Of California RECOMBINANT PATHWAY AND ORGANISMS FOR MALONYL-CoA SYNTHESIS
WO2015036273A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur herstellung von acrylsäure
WO2015036218A1 (de) 2013-09-12 2015-03-19 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
US9630900B2 (en) 2013-09-12 2017-04-25 Basf Se Method for the dehydration of 3-hydroxypropanoic acid to form acrylic acid
JP6499587B2 (ja) 2013-11-22 2019-04-10 Jmtcエンザイム株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
JP6488666B2 (ja) * 2013-11-22 2019-03-27 Agc株式会社 クローニングベクター、発現ベクターおよび形質転換体の製造方法
KR101555867B1 (ko) 2014-04-18 2015-10-01 부산대학교 산학협력단 3-하이드록시프로피온산을 분해하지 않는 슈도모나스 데니트리피칸스 결실 변이균주 및 이를 이용한 3-하이드록시프로피온산의 생산방법
EP3161142A4 (en) * 2014-06-26 2018-05-16 Lygos, Inc. Recombinant host cells for the production of malonate
WO2016026763A1 (en) 2014-08-18 2016-02-25 Basf Se Process for preparing acrylic acid using a heterogeneous alumina catalyst
US10704064B2 (en) * 2014-08-29 2020-07-07 Sk Innovation Co., Ltd. Recombinant yeast producing 3-hydroxypropionic acid and method for producing 3-hydroxypropionic acid using the same
EP2993228B1 (en) 2014-09-02 2019-10-09 Cargill, Incorporated Production of fatty acid esters
EP3205721B1 (en) 2014-10-10 2019-08-28 JMTC Enzyme Corporation Transformant and method for producing same, and method for producing lactic acid
CN107109347A (zh) * 2014-12-19 2017-08-29 诺维信公司 用于生产3‑羟基丙酸的重组宿主细胞
WO2016100910A1 (en) * 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
WO2016135020A1 (de) 2015-02-24 2016-09-01 Basf Se Verfahren zur kontinuierlichen dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2016138303A1 (en) 2015-02-27 2016-09-01 Novozymes A/S Mutant host cells for the production of 3-hydroxypropionic acid
WO2016162175A1 (de) 2015-04-07 2016-10-13 Basf Se Verfahren zur dehydratisierung von 3-hydroxypropionsäure zu acrylsäure
WO2016200239A1 (ko) * 2015-06-11 2016-12-15 부산대학교 산학협력단 3-하이드록시프로피온산에 의해 발현이 유도되는 프로모터 시스템 및 이를 이용한 3-하이드록시프로피온산의 생물학적 생산방법
EP3321364B1 (en) 2015-06-11 2022-12-28 Noroo IC Co., Ltd. Promoter system inducing expression by 3-hydroxypropionic acid and method for biological production of 3-hydroxypropionic acid using same
US10626423B2 (en) * 2015-07-21 2020-04-21 The Governing Council Of The University Of Toronto Methods and microorganisms for the production of 1,3-butanediol
US20180265902A1 (en) 2015-08-24 2018-09-20 Novozymes A/S Beta-Alanine Aminotransferases For The Production of 3-Hydroxypropionic Acid
US20180258437A1 (en) * 2015-11-12 2018-09-13 Lygos, Inc. Recombinant host cells and methods for the production of l-aspartate and beta-alanine
CA3042854A1 (en) * 2015-11-12 2017-05-18 Lygos, Inc. Recombinant host cells and methods for the anaerobic production of l-aspartate and beta-alanine
DE102016114555A1 (de) 2016-08-05 2018-02-08 Thyssenkrupp Ag Prozess zur Herstellung von Acrylsäure aus einer wässrigen 3-Hydroxypropanol-Lösung
CN110168095A (zh) 2016-12-06 2019-08-23 诺维信公司 用于使用工程化酵母菌株从含有木糖的纤维素基质生产乙醇的改善方法
EP3577227A4 (en) 2017-02-02 2020-12-30 Cargill Inc. GENETICALLY MODIFIED CELLS PRODUCING C6-C10 FATTY ACID DERIVATIVES
US11091753B2 (en) 2017-05-31 2021-08-17 Novozymes A/S Xylose fermenting yeast strains and processes thereof for ethanol production
WO2018222990A1 (en) 2017-06-02 2018-12-06 Novozymes A/S Improved yeast for ethanol production
CA3070757A1 (en) 2017-08-17 2019-02-21 Basf Se Process for continuously preparing n-butyl acrylate or isobutyl acrylate
WO2019042971A1 (en) 2017-08-29 2019-03-07 Novozymes A/S BAKERY YEAST EXPRESSING ANTI-RESTORATION / FRESHNESS AMYLASES
CA3089135A1 (en) 2018-01-29 2019-08-01 Novozymes A/S Microorganisms with improved nitrogen utilization for ethanol production
KR102419608B1 (ko) * 2018-02-08 2022-07-08 주식회사 엘지화학 고농도 3-하이드록시프로피온산 수용액의 제조 방법
CA3098718A1 (en) 2018-05-31 2019-12-05 Novozymes A/S Processes for enhancing yeast growth and productivity
EP3810786A4 (en) * 2018-06-25 2022-06-08 Lygos, Inc. RECOMBINANT HOST CELLS AND METHODS FOR PRODUCTION OF ASPARTIC ACID AND BETA-ALANINE
BR112021001282A2 (pt) 2018-07-25 2021-04-27 Novozymes A/S levedura expressando enzimas para produção de etanol
CA3114783A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
JP7370587B2 (ja) * 2018-10-30 2023-10-30 GreenEarthInstitute株式会社 有機化合物の製造方法およびコリネ型細菌
BR112021011629A2 (pt) 2018-12-18 2021-09-08 Braskem S.A. Via de coprodução de derivados de 3-hp e acetil-coa a partir de malonato semialdeído
CN109852605A (zh) * 2019-01-16 2019-06-07 徐州工程学院 一种诱变筛选高产3-羟基丙酸菌株的方法
EP4004029A1 (en) 2019-07-26 2022-06-01 Novozymes A/S Microorganisms with improved nitrogen transport for ethanol production
CN112390855B (zh) * 2019-07-31 2022-04-29 上海交通大学医学院附属仁济医院 Pretide-146a在制备缓解或治疗自身免疫性疾病的药物中的应用
BR112022002203A2 (pt) 2019-08-05 2022-09-06 Novozymes As Misturas de enzimas e processos para produção de um ingrediente alimentar com alto teor de proteína a partir de um subproduto de vinhaça completa
MX2021015818A (es) 2019-08-06 2022-02-03 Novozymes As Proteinas de fusion para mejorar la expresion de enzimas.
CA3152952A1 (en) 2019-09-16 2021-03-25 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
AU2020402990A1 (en) 2019-12-10 2022-06-09 Novozymes A/S Microorganism for improved pentose fermentation
US20240228996A1 (en) 2020-02-10 2024-07-11 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
BR112022026729A2 (pt) 2020-06-29 2023-01-24 Basf Se Aparelho e uso do aparelho para realizar processos de transferência de massa, e, método para projetar o aparelho para transferência de massa
KR102639658B1 (ko) * 2020-07-31 2024-02-22 주식회사 엘지화학 3-하이드록시프로피온산의 2단계 제조 방법
CN111985041B (zh) * 2020-09-17 2021-03-30 青岛理工大学 一种加固边坡挡墙高度确定方法及加固边坡挡墙
KR20230076829A (ko) * 2020-09-30 2023-05-31 게노미엄, 아이엔씨. 바이오아크롤레인 및 바이오아크릴산을 생산하는 발효 공정
CA3191387A1 (en) 2020-09-30 2022-04-07 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
WO2022090564A1 (en) 2020-11-02 2022-05-05 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP4242312A4 (en) * 2020-11-05 2024-04-24 Lg Chem, Ltd. Microorganisms having capability of producing 3-hydroxypropionic acid from glucose and uses thereof
EP4242319A4 (en) * 2020-11-05 2024-05-22 Lg Chem, Ltd. PROCESS FOR PRODUCING 3-HYDROXYPROPIONIC ACID
CN116348603B (zh) 2021-02-08 2024-07-02 朗泽科技有限公司 重组微生物及其用途
BR112023025624A2 (pt) 2021-06-07 2024-02-27 Novozymes As Célula de levedura recombinante, célula hospedeira recombinante, composição, cocultura, métodos de produção de um derivado de uma célula hospedeira recombinante e de produção de um produto de fermentação, e, uso de uma célula hospedeira recombinante
FR3125040B1 (fr) 2021-07-09 2024-04-26 Snf Sa Procédé d’obtention de bio-monomère à partir de diméthylaminoethanol d’origine renouvelable
FR3125042B1 (fr) 2021-07-09 2024-04-12 Snf Sa Procédé d’obtention d’alkyl(méth)acrylamide substitué biosourcé
FR3125048B1 (fr) 2021-07-09 2024-04-19 Snf Sa Polymère biosourcé à biodégradabilité améliorée
WO2023168244A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
WO2023168233A1 (en) 2022-03-03 2023-09-07 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate
CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN116024184B (zh) * 2022-07-26 2024-03-15 南京科技职业学院 醛脱氢酶突变体及其在制备5-羟甲基-2-呋喃甲酸中的应用
EP4638768A2 (en) 2022-12-19 2025-10-29 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
WO2024226289A1 (en) 2023-04-26 2024-10-31 Cargill, Incorporated Methods for producing propionic acid
AU2024303961A1 (en) 2023-06-13 2025-12-11 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
CN121794035A (zh) 2023-09-15 2026-04-03 嘉吉公司 升膜蒸发器原位清洁方法和系统
KR20250119485A (ko) * 2024-01-31 2025-08-07 주식회사 엘지화학 3-하이드록시프로피온산의 생산 방법
WO2025261823A1 (en) 2024-06-21 2025-12-26 Basf Se Process for manufacture of (meth)acrylates

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39710A (en) 1972-06-19 1975-04-25 Imi Inst For Res & Dev Recovery of acids from aqueous solutions by solvent extraction
US4771001A (en) 1986-03-27 1988-09-13 Neurex Corp. Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification
US5210296A (en) 1990-11-19 1993-05-11 E. I. Du Pont De Nemours And Company Recovery of lactate esters and lactic acid from fermentation broth
US5132456A (en) 1991-05-07 1992-07-21 The Regents Of The University Of California Sorption of carboxylic acid from carboxylic salt solutions at PHS close to or above the pKa of the acid, with regeneration with an aqueous solution of ammonia or low-molecular-weight alkylamine
US5420304A (en) 1992-03-19 1995-05-30 Biopak Technology, Ltd. Method to produce cyclic esters
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
IL109003A (en) 1994-03-16 1999-09-22 Yissum Res Dev Co Process and extractant composition for extracting water-soluble carboxylic and mineral acids
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
WO1999053035A1 (en) 1998-04-13 1999-10-21 The University Of Georgia Research Foundation, Inc. Pyruvate carboxylase overexpression for enhanced production of oxaloacetate-derived biochemicals in microbial cells
EP1975236B1 (en) * 1998-08-04 2015-05-06 Metabolix, Inc. Polyhydroxyalkanoate production from polyols
US6485947B1 (en) 1999-05-21 2002-11-26 Cargill Dow Polymers, Llc Production of lactate using crabtree negative organisms in varying culture conditions
US6852517B1 (en) 1999-08-30 2005-02-08 Wisconsin Alumni Research Foundation Production of 3-hydroxypropionic acid in recombinant organisms
DE60030403D1 (de) 1999-08-30 2006-10-12 Wisconsin Alumni Res Found Herstellung von 3-hydroxypropionsäure in rekombinanten organismen
JP4098455B2 (ja) 2000-03-10 2008-06-11 株式会社日立製作所 マーク画像中の電子透かし情報の参照方法及び計算機
CA2429039A1 (en) 2000-11-20 2002-05-30 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
US7109010B2 (en) 2000-11-22 2006-09-19 Nature Works Llc Methods and materials for the synthesis of organic products
DE60230677D1 (de) 2001-11-23 2009-02-12 Cargill Inc Verfahren und materialien zur herstellung organischer produkte in zellen von candida-spezies
ES2329778T3 (es) 2002-01-18 2009-12-01 Novozymes A/S 2,3-aminomutasa de alanina.
CN1642897A (zh) 2002-03-25 2005-07-20 嘉吉有限公司 制造β-羟基羧酸衍生物的方法
EP1513939B1 (en) 2002-05-30 2014-12-31 Cargill Inc. Fermentation process using specific oxygen uptake rates as a process control
BR0315969B1 (pt) 2002-11-01 2013-03-19 processo para preparaÇço de 1,3-propanodiol.
JP2006518766A (ja) 2003-02-24 2006-08-17 カーギル,インコーポレイティド 3−ヒドロキシカルボン酸を調製するプロセス
DE602004022305D1 (de) 2003-06-26 2009-09-10 Novozymes As Verfahren zur trennung und rückgewinnung von 3-hydroxypropionsäure und acrylsäure
BRPI0411925A (pt) 2003-06-26 2006-08-15 Cargill Inc processo para separação e recuperação de ácido 3-hidroxipropiÈnico e ácido acrìlico
US7326557B2 (en) 2003-11-14 2008-02-05 Rice University Increasing intracellular NADPH availability in E. coli
WO2005118719A2 (en) 2003-12-04 2005-12-15 Cargill, Incorporated Production of 3-hydroxypropionic acid using beta-alanine/pyruvate aminotransferase
EP2292750A3 (en) 2004-07-30 2011-12-21 Novozymes A/S Alanine 2, 3 aminomutases
US7987056B2 (en) 2004-09-20 2011-07-26 The Regents Of The University Of Colorado, A Body Corporate Mixed-library parallel gene mapping quantitative micro-array technique for genome-wide identification of trait conferring genes
MX2007004980A (es) 2004-10-25 2007-06-14 Codexis Inc Alanina 2,3-aminomutasas mejoradas, y polinucleotidos relacionados.
DK2305826T3 (en) 2005-08-10 2016-06-27 Univ Florida Materials and methods for the efficient production of lactic acid
US7846688B2 (en) 2005-08-15 2010-12-07 The Regents Of The University Of Colorado Broad host range vectors for shotgun and expression library cloning in Gram negative bacteria
DE102005048818A1 (de) * 2005-10-10 2007-04-12 Degussa Ag Mikrobiologische Herstellung von 3-Hydroxypropionsäure
BRPI0709607B1 (pt) 2006-03-13 2018-05-08 Cargill Inc cédulas de levedura tendo via rompida de diidroxi acetona fosfato para glicerol e processo de fermentação"
WO2007130745A1 (en) 2006-03-15 2007-11-15 Regents Of The University Of Colorado Enhanced alcohol tolerant microorganism and methods of use thereof
US20080103060A1 (en) 2006-08-08 2008-05-01 Regents Of The University Of Colorado Compositions and methods for chemical reporter vectors
BRPI0716212A2 (pt) 2006-08-30 2013-10-15 Cargill Inc Beta-alanina/alfa-cetoglutarato aminotransferase para produção de ácido 3-hidroxipropiônico
US8938765B2 (en) 2006-12-22 2015-01-20 Time Warner Cable Enterprises Llc Methods, apparatus and user interface for providing content on demand
BRPI0806695A2 (pt) 2007-01-12 2014-06-03 Univ Colorado Composições e métodos para aumentar a tolerância à produção de produtos químicos produzidos por microorganismos
US8673601B2 (en) 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
US8048624B1 (en) 2007-12-04 2011-11-01 Opx Biotechnologies, Inc. Compositions and methods for 3-hydroxypropionate bio-production from biomass
EP2235173A2 (en) 2007-12-19 2010-10-06 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2009089457A1 (en) * 2008-01-11 2009-07-16 Novozymes A/S Methods for producing 3-hydroxypropionic acid and compounds thereof
BRPI0915749A2 (pt) 2008-07-08 2018-07-10 Opx Biotechnologies Inc métodos, composições e sistemas para produção biossintética de 1,4-butanodiol
US20100021978A1 (en) 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
BRPI0918882A2 (pt) * 2008-07-23 2019-02-26 Opx Biotechnologies Inc métodos, sistemas e composições para tolerância aumentada de microorganismo para produção de ácido 3-hidroxipropiônico (3-hp)
US20110281314A1 (en) 2008-08-04 2011-11-17 Lynch Michael D Methods, systems and compositions related to microbial bio-production of butanol and/or isobutanol
WO2010031083A2 (en) * 2008-09-15 2010-03-18 Opx Biotechnologies, Inc. Methods, systems and compositions related to reduction of conversions of microbially produced 3-hydroxypropionic acid (3-hp) to aldehyde metabolites
WO2010059424A2 (en) 2008-11-18 2010-05-27 Novozymes, Inc. Methods and compositions for degrading cellulosic material
US20110144377A1 (en) 2009-06-16 2011-06-16 E. I. Du Pont Nemours And Company Process for the biological production of 3-hydroxypropionic acid with high yield
US8809027B1 (en) 2009-09-27 2014-08-19 Opx Biotechnologies, Inc. Genetically modified organisms for increased microbial production of 3-hydroxypropionic acid involving an oxaloacetate alpha-decarboxylase
GB2487866A (en) 2009-09-27 2012-08-08 Opx Biotechnologies Inc Method for producing 3-Hydroxypropionic acid and other products
WO2011050037A1 (en) 2009-10-23 2011-04-28 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2011063363A2 (en) 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
CA2788045A1 (en) 2010-01-27 2011-08-04 Opx Biotechnologies, Inc. Microorganism production of high-valve chemical products, and related compositions, methods and systems
EP2553111B1 (en) 2010-03-30 2016-05-11 Novozymes A/S Methods for enhancing by-products from fermentation processes
US9394555B2 (en) 2010-08-12 2016-07-19 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a dioxy compound and uses thereof
CN107828671B (zh) 2010-11-22 2022-03-08 卡吉尔公司 用于生产3-羟基丙酸的组合物和方法
US20140121118A1 (en) 2010-11-23 2014-05-01 Opx Biotechnologies, Inc. Methods, systems and compositions regarding multiplex construction protein amino-acid substitutions and identification of sequence-activity relationships, to provide gene replacement such as with tagged mutant genes, such as via efficient homologous recombination
WO2013192453A1 (en) 2012-06-20 2013-12-27 Opx Biotechnologies, Inc. Purification of 3-hydroxypropionic acid from crude cell broth and dehydration to acrylic acid
US20130345470A1 (en) 2012-06-20 2013-12-26 Opx Biotechnologies, Inc. Purification of 3-Hydroxypropionic Acid from Crude Cell Broth and Production of Acrylamide
CA2905602A1 (en) 2013-03-15 2014-09-18 Sarah M. Hoyt Flash evaporation for product purification and recovery
WO2014146026A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Bioproduction of chemicals
US20150044746A1 (en) 2013-03-15 2015-02-12 Opx Biotechnologies, Inc. Method of enhanced bioproduction
US10442749B2 (en) 2013-03-15 2019-10-15 Cargill, Incorporated Recovery of 3-hydroxypropionic acid
WO2014145332A1 (en) 2013-03-15 2014-09-18 Opx Biotechnologies, Inc. Monfunctional mcr + 3-hp dehydrogenase

Similar Documents

Publication Publication Date Title
JP2013542747A5 (https=)
JP5772594B2 (ja) 形質転換体およびその製造方法、ならびに乳酸の製造方法
CN102016024B (zh) 突变体酵母及使用其的物质生产方法
MY169074A (en) Yeast strains engineered to produce ethanol from acetic acid and glycerol
CN112725210B (zh) 抑制乳酸代谢和乙醇产生的重组耐酸酵母及使用其生产乳酸的方法
JP2013528398A5 (https=)
BR112013010169B1 (pt) Microrganismo monascus ruber, seu uso na produção de ácido láctico e método para produzir uma composição a um rendimento elevado, que compreende um ácido láctico
EP3380626A1 (en) Genetically modified yeasts and fermentation processes using genetically modified yeasts
CN106086058A (zh) 一种减少蛹虫草出菇时间及提高出菇产量的方法
JP5813977B2 (ja) Kluyveromyces属の変異体酵母及びこれを用いたエタノールの製造方法
CN116064266B (zh) 盐胁迫抗性增强的重组酿酒酵母菌及其构建方法与应用
CN107937297B (zh) 一株多抑制物胁迫耐受性酿酒酵母及制备方法、应用
CN104911118A (zh) 一种乳酸脱氢酶人源化酿酒酵母及其构建方法
CN102226154B (zh) 具有双重筛选标记的多形汉逊酵母菌及其应用
CN104450804A (zh) 一种削弱丙酮酸分解代谢强化丙酮酸积累的方法
CN103710274B (zh) 一种胞外丙酮酸产量提高的基因工程菌及其应用
CN103131718B (zh) 来源产甘油假丝酵母新型耐高渗功能基因CgHog1的克隆及其应用
CN109266566A (zh) 一种调节光滑球拟酵母渗透压胁迫的方法
CN102120966A (zh) Ura3缺陷型毕赤酵母x-33菌株的构建及应用
CN107723302B (zh) 一种过表达产甘油假丝酵母CgGAD1提高渗透压耐受性的方法
CN108949664B (zh) 一种酸胁迫抗性提高的乳酸菌工程菌及其应用
CN104845948B (zh) 一种酶活性提高的丙酮酸羧化酶突变体p474n及其应用
CN105132388A (zh) 一种酶活性提高的丙酮酸羧化酶突变体r485p及其应用
CN103923847A (zh) 一种强化前体供应增强α-酮戊二酸合成的解脂亚洛酵母
JP6253465B2 (ja) Kluyveromyces属の変異体酵母及びこれを用いたエタノールの製造方法