JP2013506490A - バイアル及び予備取り付けされた流体移送デバイスを含むバイアルアッセンブリ - Google Patents
バイアル及び予備取り付けされた流体移送デバイスを含むバイアルアッセンブリ Download PDFInfo
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
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- A—HUMAN NECESSITIES
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- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
- A61J1/1425—Snap-fit type
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2055—Connecting means having gripping means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2065—Connecting means having aligning and guiding means
Abstract
【解決手段】流体移送デバイスは、ニードルレス注射器との流体連通をシールするためのコネクタと、ニードルレス注射器とバイアル内部との間を流体連通できるようにするためにバイアルを穿刺するためのスパイク端を有するスパイクと、を含む、細長いチューブ状流れ部材を備える。スパイク端はバイアルのストッパとぴったりと密封接触する。流体移送デバイスは、更に、最初はコネクタをシールし、取り外されたときにコネクタを露出する、手動で取り外すことができる閉鎖体を備える。
【選択図】図3
Description
101・・・バイアル
101A・・・長手方向軸線
102・・・流体移送デバイス
102A・・・長手方向軸線
103・・・バイアル本体
104・・・バイアル内部
106・・・薬剤
107・・・バイアルリム
108・・・バイアルネック
109・・・ストッパ
109A・・・最上ストッパ面
111・・・バンド
112・・・めくら穴
112A・・・穴端
113・・・チューブ状流れ部材
114・・・コネクタ
116・・・スパイク
116A・・・スパイク端
117・・・内腔
118・・・雄ねじ
119・・・閉鎖体
120・・・流れ部材拘束構成
121・・・環状フランジ
130・・・流れ部材固定構成
131・・・半径方向返し
140・・・注射器
142・・・希釈剤
Claims (17)
- ニードルレス注射器とともに使用するためのバイアルアッセンブリであって、
(a)長手方向軸線を有するバイアルであって、医薬品を貯蔵するためのバイアル内部を有するバイアル本体と、バイアル開口部を形成するバイアルリムと、前記バイアルをシールするためのストッパとを含む、バイアルを備え、
前記ストッパは、最上ストッパ面と、予備成形された軸線方向のめくら穴とを有し、前記めくら穴の穴端では、前記めくら穴と前記バイアル内部との間のストッパの厚さが縮小され、
前記バイアルアッセンブリは、また、
(b)前記バイアルの長手方向軸線と実質的に同軸に整合された長手方向軸線を有する流体移送デバイスを備え、
前記流体移送デバイスは、
i)前記ニードルレス注射器との流体連通をシールするためのコネクタと、
前記ニードルレス注射器と前記バイアル内部との間を流体連通できるようにするために、前記ストッパを穿刺するためのスパイク端を有するスパイクと、
を有する細長いチューブ状流れ部材を含み、
前記流れ部材は、前記スパイク端が前記ストッパ内に配置された初期流体未連通セットアップ位置から流体連通位置まで手動で押圧され、前記流体連通位置において、前記スパイク端が前記穴端を穿刺して前記バイアル内部内に所定距離突出し流体連通できるようになっており、
前記スパイク端は、前記流体未連通セットアップ位置では前記ストッパとぴったりと密封接触しており、前記流体連通位置では前記穴端を越えて前記バイアル内部内に突出し、
前記流体移送デバイスは、また、
ii)最初、前記流体未連通セットアップ位置で前記コネクタをシールし、取り外されると、前記ニードルレス注射器に密封をなして連通できるようにするために、前記流体連通位置で前記コネクタを露出するための、手動で取り外すことができる閉鎖体を備える、バイアルアッセンブリ。 - 請求項1に記載のバイアルアッセンブリであって、
前記コネクタは外ねじを有し、
前記閉鎖体は、前記外ねじに螺着するねじキャップによって構成され、これによって、前記ねじキャップを捩じって前記ねじから外すとき、前記流れ部材固定構成により、前記流れ部材が前記ストッパに対して回転しないようにされる、アッセンブリ。 - 請求項1又は2に記載のバイアルアッセンブリであって、
前記流体移送デバイスは、前記流体連通位置において、前記流れ部材の変位を前記所定距離で停止するための流れ部材拘束構成を含む、バイアルアッセンブリ。 - 請求項2に記載のバイアルアッセンブリであって、
前記流れ部材拘束構成は、前記コネクタと前記スパイクとの中間のフランジを含み、
前記フランジは、前記流体未連通セットアップ位置において、前記最上ストッパ面の上方に配置され、前記流体連通位置において、前記最上ストッパ面に当接する、バイアルアッセンブリ。 - 請求項1乃至4のうちのいずれか一項に記載のバイアルアッセンブリであって、
前記流体移送デバイスは、前記閉鎖体を前記コネクタから手動で取り外すとき、前記流れ部材が上方に変位しないようにするための流れ部材固定構成を含む、バイアルアッセンブリ。 - 請求項5に記載のバイアルアッセンブリにおいて、
前記流れ部材固定構成は、前記流れ部材に沿った少なくとも一つの返であって、前記流体未連通セットアップ位置において、前記最上ストッパ面の上方に配置され、前記流体連通位置において前記ストッパ内に配置される返しを含む、バイアルアッセンブリ。 - 請求項1乃至6のうちのいずれか一項に記載のバイアルアッセンブリであって、
前記流体移送デバイスは、更に、前記流れ部材が前記流体未連通セットアップ位置から前記流体連通位置まで誤って変位しないようにする安全キャッチ機構を含む、バイアルアッセンブリ。 - 請求項7に記載のバイアルアッセンブリであって、
前記流体移送デバイスは、更に、ひとたび使用者が前記安全キャッチ機構を、前記流れ部材を前記流体未連通セットアップ位置から前記流体連通位置までいつでも手動で押圧することができるように前記安全キャッチ機構を準備した後、使用者が前記安全キャッチ機構をその初期位置に戻すことを阻止するための変更防止構成を含む、バイアルアッセンブリ。 - 請求項7に記載のバイアルアッセンブリであって、
前記バイアルは、前記バイアルリムと前記バイアル本体との中間にバイアルネックを含み、
前記流れ部材拘束構成は、前記コネクタと前記スパイクとの中間にフランジを含み、
前記フランジは、前記流体未連通セットアップ位置において前記最上ストッパ面の上方に配置されており、
前記安全キャッチ機構は、前記フランジをグリップするための上方フランジグリップと、前記バイアルネックをグリップするための下方ネックグリップと、及び前記上方フランジグリップと前記下方ネックグリップとの間を延びる直立ロッドとを有する、取り外し自在の安全キャッチを含む、バイアルアッセンブリ。 - 請求項7に記載のバイアルアッセンブリであって、
前記安全キャッチ機構は、前記取り外し自在の安全キャッチを前記バイアルから取り外すための安全プルリングを含み、
前記安全プルリングは、
前記バイアルの長手方向軸線と同じ方向に延びる初期下方位置を有し、
前記安全キャッチを取り外すことができるようにするために、前記バイアルの長手方向軸線に対して横方向の位置に手動で上方に押圧される、バイアルアッセンブリ。 - 請求項10に記載のバイアルアッセンブリであって、
前記安全プルリングが前記横方向位置から前記初期下方位置に戻らないようにするための戻り止めを含む、バイアルアッセンブリ。 - 請求項7に記載のバイアルアッセンブリにおいて、
前記安全キャッチ機構は、バイアルグリップ部材であって、
前記バイアルリムに入れ子式にスナップ嵌めするための、下方に垂下した間隔が隔てられた撓み部材と、
前記流れ部材と一体形成され、前記バイアルグリップ部材に入れ子式に取り付けられたキャップ状部材であって、前記スパイク端を、前記ストッパを貫通して前記バイアル内部内に押圧するために、前記流体未連通セットアップ位置から前記流体連通位置まで手動で押圧するためのキャップ状部材と
を有するバイアルグリップ部材を含む、バイアルアッセンブリ。 - 請求項12に記載のバイアルアッセンブリであって、
前記バイアルグリップ部材は、半径方向の外側に向いたピンが設けられた、少なくとも一つの直立し、弾性的に撓むことができるキャッチ部材を含み、
前記キャップ状部材は少なくとも一つのスロットを含み、
前記少なくとも一つの半径方向の外側に向いたピンは、前記キャップ状部材を前記バイアルグリップ部材に入れ子式に取り付けることができるように、対応する前記スロットに沿って移動する、バイアルアッセンブリ。 - 請求項13に記載のバイアルアッセンブリであって、
前記スロットの各々は、前記バイアルアッセンブリが直立位置にある場合に、開放端が反時計回り方向に向いた略U字形状の形態を有し、これによって前記流れ部材固定構成として作用する、バイアルアッセンブリ。 - 請求項14に記載のバイアルアッセンブリであって、
前記スロットの各々は、実質的に水平な最下部分、実質的に水平な最上部分、及び前記実質的に水平な最下部分と前記実質的に水平な最上部分との間に延びて、上方に傾斜した部分を含み、
ラッチ部材が、前記実質的に水平な最上部分と、前記上方に傾斜した部分との間の接続箇所に配置されており、
これによって、前記半径方向の外側に向いたピンは、ひとたび使用者が前記安全キャッチ機構を、前記流れ部材を前記初期セットアップ位置から前記流体連通位置までいつでも手動で押圧することができるように前記安全キャッチ機構を準備した後、使用者が前記安全キャッチ機構をその初期位置に戻すことを阻止するため、前記流体連通において、対応する前記ラッチ部材を乗り越える、バイアルアッセンブリ。 - 請求項1乃至15のうちのいずれか一項に記載のバイアルアッセンブリで使用するためのバイアル。
- 請求項1乃至15のうちのいずれか一項に記載のバイアルアッセンブリで使用するための流体移送デバイス。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL201323A IL201323A0 (en) | 2009-10-01 | 2009-10-01 | Fluid transfer device for assembling a vial with pre-attached female connector |
IL201323 | 2009-10-01 | ||
PCT/IL2010/000777 WO2011039747A1 (en) | 2009-10-01 | 2010-09-21 | Vial assemblage with vial and pre-attached fluid transfer device |
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JP2013506490A true JP2013506490A (ja) | 2013-02-28 |
JP5575905B2 JP5575905B2 (ja) | 2014-08-20 |
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JP2012531551A Expired - Fee Related JP5575905B2 (ja) | 2009-10-01 | 2010-09-21 | バイアル及び予備取り付けされた流体移送デバイスを含むバイアルアッセンブリ |
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US (1) | US8998875B2 (ja) |
EP (1) | EP2470148A1 (ja) |
JP (1) | JP5575905B2 (ja) |
CN (1) | CN102548523A (ja) |
BR (1) | BR112012007326A2 (ja) |
IL (2) | IL201323A0 (ja) |
WO (1) | WO2011039747A1 (ja) |
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KR20160032040A (ko) * | 2013-05-29 | 2016-03-23 | 인두스트리에 볼라 에스.피.에이. | 바이알 접근 장치 |
JP2016519978A (ja) * | 2013-05-29 | 2016-07-11 | インドゥストリー・ボルラ・ソシエタ・ペル・アチオニIndustrie Borla S.p.A. | バイアルアクセスデバイス |
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Also Published As
Publication number | Publication date |
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US8998875B2 (en) | 2015-04-07 |
IL218730A0 (en) | 2012-06-28 |
EP2470148A1 (en) | 2012-07-04 |
CN102548523A (zh) | 2012-07-04 |
WO2011039747A1 (en) | 2011-04-07 |
IL201323A0 (en) | 2010-05-31 |
US20120184938A1 (en) | 2012-07-19 |
BR112012007326A2 (pt) | 2016-10-04 |
JP5575905B2 (ja) | 2014-08-20 |
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