JP2012526726A - 薬物動態が改善された鼻腔内用薬学的組成物 - Google Patents

薬物動態が改善された鼻腔内用薬学的組成物 Download PDF

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Publication number
JP2012526726A
JP2012526726A JP2011548484A JP2011548484A JP2012526726A JP 2012526726 A JP2012526726 A JP 2012526726A JP 2011548484 A JP2011548484 A JP 2011548484A JP 2011548484 A JP2011548484 A JP 2011548484A JP 2012526726 A JP2012526726 A JP 2012526726A
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pharmaceutical formulation
therapeutic agent
micrometers
free base
administered
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JP2012526726A5 (enExample
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良一 永田
俊志 治田
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Shin Nippon Biomedical Laboratories Ltd
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Shin Nippon Biomedical Laboratories Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2011548484A 2009-05-15 2010-05-14 薬物動態が改善された鼻腔内用薬学的組成物 Pending JP2012526726A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17890009P 2009-05-15 2009-05-15
US61/178,900 2009-05-15
PCT/JP2010/003285 WO2010131486A1 (en) 2009-05-15 2010-05-14 Intranasal pharmaceutical compositions with improved pharmacokinetics

Publications (2)

Publication Number Publication Date
JP2012526726A true JP2012526726A (ja) 2012-11-01
JP2012526726A5 JP2012526726A5 (enExample) 2013-06-27

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JP2011548484A Pending JP2012526726A (ja) 2009-05-15 2010-05-14 薬物動態が改善された鼻腔内用薬学的組成物

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Country Link
US (1) US9101539B2 (enExample)
EP (1) EP2429495A4 (enExample)
JP (1) JP2012526726A (enExample)
WO (1) WO2010131486A1 (enExample)

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WO2025220834A1 (ko) * 2024-04-16 2025-10-23 한미약품 주식회사 흡입제 조성물

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