JP2011526244A5 - - Google Patents

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Publication number
JP2011526244A5
JP2011526244A5 JP2011501003A JP2011501003A JP2011526244A5 JP 2011526244 A5 JP2011526244 A5 JP 2011526244A5 JP 2011501003 A JP2011501003 A JP 2011501003A JP 2011501003 A JP2011501003 A JP 2011501003A JP 2011526244 A5 JP2011526244 A5 JP 2011526244A5
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JP
Japan
Prior art keywords
mif
disease
cancer
domain
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011501003A
Other languages
English (en)
Japanese (ja)
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JP2011526244A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/037887 external-priority patent/WO2009117710A2/en
Publication of JP2011526244A publication Critical patent/JP2011526244A/ja
Publication of JP2011526244A5 publication Critical patent/JP2011526244A5/ja
Pending legal-status Critical Current

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JP2011501003A 2008-03-20 2009-03-20 炎症の処置方法 Pending JP2011526244A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US3838108P 2008-03-20 2008-03-20
US61/038,381 2008-03-20
US3937108P 2008-03-25 2008-03-25
US61/039,371 2008-03-25
US4580708P 2008-04-17 2008-04-17
US61/045,807 2008-04-17
US12109508P 2008-12-09 2008-12-09
US61/121,095 2008-12-09
PCT/US2009/037887 WO2009117710A2 (en) 2008-03-20 2009-03-20 Methods of treating inflammation

Publications (2)

Publication Number Publication Date
JP2011526244A JP2011526244A (ja) 2011-10-06
JP2011526244A5 true JP2011526244A5 (enExample) 2011-11-24

Family

ID=41091567

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2011501003A Pending JP2011526244A (ja) 2008-03-20 2009-03-20 炎症の処置方法
JP2011501000A Pending JP2011515416A (ja) 2008-03-20 2009-03-20 抗mif抗体を用いる処置方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011501000A Pending JP2011515416A (ja) 2008-03-20 2009-03-20 抗mif抗体を用いる処置方法

Country Status (14)

Country Link
US (2) US20110262386A1 (enExample)
EP (2) EP2252318A4 (enExample)
JP (2) JP2011526244A (enExample)
KR (1) KR20110014141A (enExample)
CN (2) CN102046199A (enExample)
AU (2) AU2009225389A1 (enExample)
BR (1) BRPI0910259A2 (enExample)
CA (2) CA2717071A1 (enExample)
CO (1) CO6300848A2 (enExample)
EA (1) EA201001529A1 (enExample)
IL (1) IL207752A0 (enExample)
MX (1) MX2010010198A (enExample)
NZ (1) NZ588033A (enExample)
WO (2) WO2009117710A2 (enExample)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009117710A2 (en) * 2008-03-20 2009-09-24 Carolus Therapeutics, Inc. Methods of treating inflammation
US20110070184A1 (en) * 2008-03-24 2011-03-24 Carolus Therpeutics, Inc. Methods and compositions for treating atherosclerosis and related condidtions
WO2010056910A2 (en) * 2008-11-12 2010-05-20 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders
WO2011038149A2 (en) * 2009-09-23 2011-03-31 Carolus Therapeutics, Inc. Methods of treating inflammation
EP2308485A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP2308484A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
WO2012125680A1 (en) 2011-03-16 2012-09-20 Novartis Ag Methods of treating vasculitis using an il-17 binding molecule
US9133164B2 (en) * 2011-04-13 2015-09-15 Innov88 Llc MIF inhibitors and their uses
TWI407964B (zh) * 2011-05-10 2013-09-11 Univ Fu Jen Catholic 干擾性核糖核酸用於治療或減緩疼痛之用途
EP3626739A1 (en) 2011-06-24 2020-03-25 Stephen D. Gillies Light chain immunoglobulin fusion proteins and methods of use thereof
US10596233B2 (en) 2011-06-30 2020-03-24 Dignity Health Use of pertussis toxin as a therapeutic agent
CA2831154C (en) 2011-06-30 2021-01-12 Dignity Health Use of pertussis toxin as a therapeutic agent
JP2014526886A (ja) 2011-07-15 2014-10-09 モルフォシス・アー・ゲー マクロファージ遊走阻止因子(mif)とd−ドーパクロームトートメラーゼ(d−dt)に交差反応性がある抗体
CN102357249A (zh) * 2011-10-26 2012-02-22 广州赫尔氏药物开发有限公司 能够抑制耐药性结核杆菌的药物
EP3338776A1 (en) 2012-05-01 2018-06-27 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
US10561676B2 (en) * 2013-08-02 2020-02-18 Syntrix Biosystems Inc. Method for treating cancer using dual antagonists of CXCR1 and CXCR2
US10046002B2 (en) 2013-08-02 2018-08-14 Syntrix Biosystems Inc. Method for treating cancer using chemokine antagonists
EP3052526A4 (en) 2013-10-03 2017-04-19 Oregon Health & Science University Recombinant polypeptides comprising mhc class ii 1 domains
EP3242685B1 (en) * 2015-01-09 2022-05-04 AdAlta Limited Cxcr4 binding molecules
TW201718851A (zh) * 2015-09-18 2017-06-01 通用醫院公司 具有抗化學排斥(anti-fugetactic)性質之經修飾自然殺手細胞及其用途
WO2017106332A1 (en) 2015-12-14 2017-06-22 X4 Pharmaceuticals, Inc. Methods for treating cancer
ES2907489T3 (es) * 2015-12-14 2022-04-25 X4 Pharmaceuticals Inc Métodos para el tratamiento del cáncer
CN109152780B (zh) 2016-03-11 2021-10-01 阿迪亚生命科学公司 用于治疗结晶性关节病症的cxcr-2抑制剂
KR102645432B1 (ko) * 2016-03-28 2024-03-11 (주)아모레퍼시픽 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법
WO2017177230A1 (en) 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
US20190134231A1 (en) * 2016-04-21 2019-05-09 The Board Of Regents Of The University Of Texas System Methods and compositions for detecting aneurysms
JP7461741B2 (ja) 2016-06-20 2024-04-04 カイマブ・リミテッド 抗pd-l1およびil-2サイトカイン
JP7054529B2 (ja) 2016-06-21 2022-04-14 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
WO2017223229A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
CA3027500A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
JP7252125B2 (ja) * 2016-10-03 2023-04-04 ザ チルドレンズ メディカル センター コーポレーション 糖尿病性腎症の予防および処置
CN108355133A (zh) * 2017-01-26 2018-08-03 中国医学科学院阜外医院 靶向cxcr7的药物组合物和方法
US11767564B2 (en) * 2017-10-27 2023-09-26 Board Of Regents, The University Of Texas System Use of SDHA as a prognostic marker and therapeutic target in uveal melanoma
CN107964045B (zh) * 2017-12-18 2021-04-23 南京医科大学 一种人鼠嵌合抗CXCR2全分子IgG及其应用
CN112368011A (zh) 2018-04-11 2021-02-12 俄亥俄州创新基金会 缓释微粒用于眼用药物递送的方法和组合物
US11679146B2 (en) 2018-06-05 2023-06-20 Anji Pharmaceuticals Inc. Compositions and methods for treating pancreatitis
CA3098415A1 (en) * 2018-06-07 2019-12-12 Oncoone Research & Development Gmbh Anti-oxmif/anti-cd3 antibody for cancer treatment
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
MX2021007604A (es) * 2018-12-26 2021-08-11 Colgate Palmolive Co Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis.
CN110133306B (zh) * 2019-05-09 2023-04-07 北京勤邦生物技术有限公司 检测西马特罗的酶联免疫试剂盒及其应用
JP2023517956A (ja) 2020-03-10 2023-04-27 エックス4 ファーマシューティカルズ, インコーポレイテッド 好中球減少症を処置する方法
WO2021181398A1 (en) * 2020-03-11 2021-09-16 Biolinerx Ltd. Cxcr4 inhibitor for the treatment of acute respiratory distress syndrome and viral infections
US20210338626A1 (en) * 2020-04-28 2021-11-04 Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch Methods for treating or preventing a viral infection or inhibiting viral replication
EP4237002A4 (en) * 2020-10-28 2025-02-12 University Health Network METHODS OF TREATING SPONDYLOARTHRITIS OR SYMPTOMS THEREOF
JP2024512499A (ja) * 2021-03-22 2024-03-19 クリップスビーエヌシー・カンパニー・リミテッド 新規な組換えマイコバクテリウムスメグマチス菌株およびその用途
JP2024516548A (ja) 2021-04-08 2024-04-16 ジョスリン ダイアビーティス センター インコーポレイテッド 腎機能低下の診断及び予測の方法
KR102561554B1 (ko) * 2021-04-14 2023-07-28 부산대학교 산학협력단 치주질환 진단용 바이오마커 조성물, 치주질환 치료 효용성 평가용 바이오마커 조성물 및 이를 이용한 진단키트
EP4472735A2 (en) * 2022-02-04 2024-12-11 University of Pittsburgh - of the Commonwealth System of Higher Education Methods of detecting and treating cerebral aneurysms
WO2025171411A1 (en) * 2024-02-09 2025-08-14 Herophilus, Inc. Compositions and methods related to modulating macrophage migration inhibitory factor (mif)-cd74 signaling and related treatments for neuroinflammatory conditions
CN121714692A (zh) * 2026-02-26 2026-03-24 华中科技大学同济医学院附属协和医院 Cxcl14抑制剂在制备用于预防或治疗患者腹主动脉瘤的药物中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE474597T1 (de) * 1993-05-17 2010-08-15 Cytokine Pharmasciences Inc Inhibition des migrations-inhibitions-faktors in der behandlung von krankheiten bei denen eine cytokin-vermittelte toxizität eine rolle spielt
US6080407A (en) * 1993-05-17 2000-06-27 The Picower Institute For Medical Research Diagnostic assays for MIF
US20070072861A1 (en) * 2000-03-27 2007-03-29 Barbara Roniker Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders
CN1842346A (zh) * 2001-01-12 2006-10-04 塞托凯恩药物科学公司 由巨噬细胞迁移抑制因子调节细胞毒性淋巴细胞反应
WO2003047622A1 (fr) * 2001-11-30 2003-06-12 Jun Nishihira Remedes pour la sclerose en plaques
JP2003226653A (ja) * 2001-11-30 2003-08-12 Jun Nishihira 多発性硬化症治療剤
US6656168B2 (en) * 2001-12-18 2003-12-02 Kimberly-Clark Worldwide, Inc. Feminine care product with discrete areas of a skin wellness additive
AU2003213647A1 (en) * 2002-02-27 2003-09-09 Emory University Multimeric binding complexes
JP4472351B2 (ja) * 2002-03-01 2010-06-02 イミューノメディクス、インコーポレイテッド インターナライジング抗cd74抗体およびその使用方法
AU2002343174A1 (en) * 2002-11-25 2004-06-18 Rachid Ennamany Betaine and salicylic acid compositions
TW200418829A (en) * 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
US20050202010A1 (en) * 2003-08-29 2005-09-15 Giroir Brett P. Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor
WO2005065328A2 (en) * 2003-12-30 2005-07-21 The United States Of America, As Represented By The Department Of Veterans Affairs Macrophage migration inhibitory factor (mif) as marker for urological inflammatory disease
WO2006105666A1 (en) * 2005-04-06 2006-10-12 Queen's University At Kingston Administration of macrophage targeted formulations of compounds which modulate cholesterol-metabolizing enzymes for treatment of atherosclerosis
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
JPWO2007138961A1 (ja) * 2006-05-29 2009-10-08 レドックス・バイオサイエンス株式会社 マクロファージ遊走阻止因子阻害剤
WO2009117710A2 (en) * 2008-03-20 2009-09-24 Carolus Therapeutics, Inc. Methods of treating inflammation
US20110070184A1 (en) * 2008-03-24 2011-03-24 Carolus Therpeutics, Inc. Methods and compositions for treating atherosclerosis and related condidtions
WO2010056910A2 (en) * 2008-11-12 2010-05-20 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders
WO2010065491A2 (en) * 2008-12-01 2010-06-10 Carolus Therapeutics, Inc. Methods of treating inflammatory disorders

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