MX2010010198A - Metodos para tratamiento de inflamacion. - Google Patents

Metodos para tratamiento de inflamacion.

Info

Publication number
MX2010010198A
MX2010010198A MX2010010198A MX2010010198A MX2010010198A MX 2010010198 A MX2010010198 A MX 2010010198A MX 2010010198 A MX2010010198 A MX 2010010198A MX 2010010198 A MX2010010198 A MX 2010010198A MX 2010010198 A MX2010010198 A MX 2010010198A
Authority
MX
Mexico
Prior art keywords
mif
cxcr2
peptide
disease
cancer
Prior art date
Application number
MX2010010198A
Other languages
English (en)
Spanish (es)
Inventor
Christian Weber
Juergen Bernhagen
Joshua Robert Schultz
Benedikt Vollrath
Alma Zernecke
Original Assignee
Carolus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carolus Therapeutics Inc filed Critical Carolus Therapeutics Inc
Publication of MX2010010198A publication Critical patent/MX2010010198A/es

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
MX2010010198A 2008-03-20 2009-03-20 Metodos para tratamiento de inflamacion. MX2010010198A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US3838108P 2008-03-20 2008-03-20
US3937108P 2008-03-25 2008-03-25
US4580708P 2008-04-17 2008-04-17
US12109508P 2008-12-09 2008-12-09
PCT/US2009/037887 WO2009117710A2 (en) 2008-03-20 2009-03-20 Methods of treating inflammation

Publications (1)

Publication Number Publication Date
MX2010010198A true MX2010010198A (es) 2010-12-21

Family

ID=41091567

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010010198A MX2010010198A (es) 2008-03-20 2009-03-20 Metodos para tratamiento de inflamacion.

Country Status (14)

Country Link
US (2) US20110044988A1 (enExample)
EP (2) EP2252318A4 (enExample)
JP (2) JP2011526244A (enExample)
KR (1) KR20110014141A (enExample)
CN (2) CN102046199A (enExample)
AU (2) AU2009225389A1 (enExample)
BR (1) BRPI0910259A2 (enExample)
CA (2) CA2717365A1 (enExample)
CO (1) CO6300848A2 (enExample)
EA (1) EA201001529A1 (enExample)
IL (1) IL207752A0 (enExample)
MX (1) MX2010010198A (enExample)
NZ (1) NZ588033A (enExample)
WO (2) WO2009117706A2 (enExample)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110014141A (ko) * 2008-03-20 2011-02-10 카롤러스 테라퓨틱스, 인코포레이티드 염증을 치료하는 방법
CA2716628A1 (en) * 2008-03-24 2009-10-01 Carolus Therapeutics, Inc. Methods and compositions for treating atherosclerosis and related conditions
US20100183598A1 (en) * 2008-11-12 2010-07-22 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders
WO2011038149A2 (en) * 2009-09-23 2011-03-31 Carolus Therapeutics, Inc. Methods of treating inflammation
EP2308485A1 (en) * 2009-10-06 2011-04-13 Dompé S.p.a. Sulfonamides for the prevention of diabetes
EP2308484A1 (en) 2009-10-06 2011-04-13 Dompé S.p.a. Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets
WO2012125680A1 (en) 2011-03-16 2012-09-20 Novartis Ag Methods of treating vasculitis using an il-17 binding molecule
US9133164B2 (en) * 2011-04-13 2015-09-15 Innov88 Llc MIF inhibitors and their uses
TWI407964B (zh) * 2011-05-10 2013-09-11 Univ Fu Jen Catholic 干擾性核糖核酸用於治療或減緩疼痛之用途
US11492383B2 (en) 2011-06-24 2022-11-08 Stephen D. Gillies Light chain immunoglobulin fusion proteins and methods of use thereof
US10596233B2 (en) 2011-06-30 2020-03-24 Dignity Health Use of pertussis toxin as a therapeutic agent
WO2013003786A1 (en) * 2011-06-30 2013-01-03 Dignity Health Use of pertussis toxin as a therapeutic agent
US9238689B2 (en) 2011-07-15 2016-01-19 Morpho Sys AG Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT)
CN102357249A (zh) * 2011-10-26 2012-02-22 广州赫尔氏药物开发有限公司 能够抑制耐药性结核杆菌的药物
CA3095012C (en) 2012-05-01 2023-02-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
US10046002B2 (en) 2013-08-02 2018-08-14 Syntrix Biosystems Inc. Method for treating cancer using chemokine antagonists
US10561676B2 (en) * 2013-08-02 2020-02-18 Syntrix Biosystems Inc. Method for treating cancer using dual antagonists of CXCR1 and CXCR2
WO2015051330A1 (en) 2013-10-03 2015-04-09 Oregon Health & Science University RECOMBINANT POLYPEPTIDES COMPRISING MHC CLASS II α1 DOMAINS
DK3242685T3 (da) 2015-01-09 2022-07-25 Adalta Ltd Cxcr4-bindende molekyler
TW201718851A (zh) * 2015-09-18 2017-06-01 通用醫院公司 具有抗化學排斥(anti-fugetactic)性質之經修飾自然殺手細胞及其用途
CN109069486A (zh) 2015-12-14 2018-12-21 X4 制药有限公司 治疗癌症的方法
CN109069426B (zh) * 2015-12-14 2021-10-29 X4 制药有限公司 治疗癌症的方法
CN109152780B (zh) 2016-03-11 2021-10-01 阿迪亚生命科学公司 用于治疗结晶性关节病症的cxcr-2抑制剂
KR102645432B1 (ko) * 2016-03-28 2024-03-11 (주)아모레퍼시픽 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
WO2017184683A1 (en) * 2016-04-21 2017-10-26 The Board Of Regents Of The University Of Taxas System Methods and compositions for detecting aneurysms
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
JP6994767B2 (ja) 2016-06-21 2022-01-14 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
EP3808748B1 (en) 2016-06-21 2026-05-20 X4 Pharmaceuticals, Inc. Substituted piperidines as cxcr4-inhibitors
US10988465B2 (en) 2016-06-21 2021-04-27 X4 Pharmaceuticals, Inc. CXCR4 inhibitors and uses thereof
WO2018067548A1 (en) 2016-10-03 2018-04-12 The Children's Medicial Center Corporation Prevention and treatment of diabetic nephropathy
CN108355133A (zh) * 2017-01-26 2018-08-03 中国医学科学院阜外医院 靶向cxcr7的药物组合物和方法
US11767564B2 (en) * 2017-10-27 2023-09-26 Board Of Regents, The University Of Texas System Use of SDHA as a prognostic marker and therapeutic target in uveal melanoma
CN107964045B (zh) * 2017-12-18 2021-04-23 南京医科大学 一种人鼠嵌合抗CXCR2全分子IgG及其应用
KR20210009315A (ko) 2018-04-11 2021-01-26 오하이오 스테이트 이노베이션 파운데이션 안약 전달용 서방형 마이크로 입자를 이용한 방법 및 조성물
CA3102032A1 (en) 2018-06-05 2019-12-12 Anji Pharma (Us) Llc Compositions and methods for treating pancreatitis
US20220002398A1 (en) * 2018-06-07 2022-01-06 Oncoone Research & Development Gmbh ANTI-oxMIF/ANTI-CD3 ANTIBODY FOR CANCER TREATMENT
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
CA3123290A1 (en) * 2018-12-26 2020-07-02 Colgate-Palmolive Company Biomarkers of neutrophil deregulation as diagnostic for gingivitis
CN110133306B (zh) * 2019-05-09 2023-04-07 北京勤邦生物技术有限公司 检测西马特罗的酶联免疫试剂盒及其应用
CN115515585A (zh) 2020-03-10 2022-12-23 X4 制药有限公司 用于治疗中性粒细胞减少症的方法
JP2023517616A (ja) * 2020-03-11 2023-04-26 バイオラインアールエックス・リミテッド 急性呼吸窮迫症候群およびウイルス感染の治療用のcxcr4阻害剤
WO2021219495A1 (en) * 2020-04-28 2021-11-04 Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch Methods for treating or preventing a viral infection or inhibiting viral replication
US20230404980A1 (en) * 2020-10-28 2023-12-21 University Health Network Methods of treating spondyloarthritis or symptoms thereof
EP4317441A4 (en) * 2021-03-22 2025-09-17 Clipsbnc Co Ltd NEW RECOMBINANT STRAIN OF MYCOBACTERIUM SMEGMATIS AND ITS USE
CA3214688A1 (en) 2021-04-08 2022-10-13 Andrzej KROLEWSKI Methods of diagnosing and predicting renal decline
KR102561554B1 (ko) * 2021-04-14 2023-07-28 부산대학교 산학협력단 치주질환 진단용 바이오마커 조성물, 치주질환 치료 효용성 평가용 바이오마커 조성물 및 이를 이용한 진단키트
EP4472735A4 (en) * 2022-02-04 2026-06-03 Univ Pittsburgh Commonwealth Sys Higher Education METHODS FOR DETECTING AND TREATMENT OF CEREBRAL ANEURYSMS
CN117771224A (zh) * 2023-12-28 2024-03-29 山东大学齐鲁医院 一种用于预防和/或治疗腹主动脉瘤的药物及其应用
WO2025171411A1 (en) * 2024-02-09 2025-08-14 Herophilus, Inc. Compositions and methods related to modulating macrophage migration inhibitory factor (mif)-cd74 signaling and related treatments for neuroinflammatory conditions
CN121714692B (zh) * 2026-02-26 2026-06-02 华中科技大学同济医学院附属协和医院 Cxcl14抑制剂在制备用于预防或治疗患者腹主动脉瘤的药物中的应用
CN121971656A (zh) * 2026-04-09 2026-05-05 四川省医学科学院·四川省人民医院 一种靶向cxcl7基因的组合物及其在制备真菌性角膜炎药物中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6645493B1 (en) * 1993-05-17 2003-11-11 The Picower Institute For Medical Research Composition containing anti-MIF antibody
WO1994026307A1 (en) * 1993-05-17 1994-11-24 The Picower Institute For Medical Research Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine-mediated toxicity
US20070072861A1 (en) * 2000-03-27 2007-03-29 Barbara Roniker Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders
MXPA03006275A (es) * 2001-01-12 2005-09-08 Cytokine Pharmasciences Inc Metodo y composiciones para modular la regulacion de la respuesta de linfocitos citotoxicos por el factor inhibidor de la migracion de macrofagos.
WO2003047622A1 (fr) * 2001-11-30 2003-06-12 Jun Nishihira Remedes pour la sclerose en plaques
JP2003226653A (ja) * 2001-11-30 2003-08-12 Jun Nishihira 多発性硬化症治療剤
US6656168B2 (en) * 2001-12-18 2003-12-02 Kimberly-Clark Worldwide, Inc. Feminine care product with discrete areas of a skin wellness additive
WO2003072753A2 (en) * 2002-02-27 2003-09-04 Emory University Multimeric binding complexes
KR101017732B1 (ko) * 2002-03-01 2011-02-28 이뮤노메딕스, 인코오포레이티드 내재화 항-cd74 항체 및 그 이용방법
WO2004049095A2 (en) * 2002-11-25 2004-06-10 Jallal Messadek Betaine and salicylic acid compositions
TW200418829A (en) * 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
US20050202010A1 (en) * 2003-08-29 2005-09-15 Giroir Brett P. Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor
US7897349B2 (en) * 2003-12-30 2011-03-01 The United States Of America As Represented By The Department Of Veterans Affairs Macrophage migration inhibitory factor (MIF) as marker for urological inflammatory disease
WO2006105666A1 (en) * 2005-04-06 2006-10-12 Queen's University At Kingston Administration of macrophage targeted formulations of compounds which modulate cholesterol-metabolizing enzymes for treatment of atherosclerosis
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
WO2007138961A1 (ja) * 2006-05-29 2007-12-06 Redox Bioscience Inc. マクロファージ遊走阻止因子によって引き起こされる障害の予防乃至治療剤
KR20110014141A (ko) * 2008-03-20 2011-02-10 카롤러스 테라퓨틱스, 인코포레이티드 염증을 치료하는 방법
CA2716628A1 (en) * 2008-03-24 2009-10-01 Carolus Therapeutics, Inc. Methods and compositions for treating atherosclerosis and related conditions
US20100183598A1 (en) * 2008-11-12 2010-07-22 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders
WO2010065491A2 (en) * 2008-12-01 2010-06-10 Carolus Therapeutics, Inc. Methods of treating inflammatory disorders

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