BRPI0910259A2 - métodos de tratamento de inflamação - Google Patents
métodos de tratamento de inflamaçãoInfo
- Publication number
- BRPI0910259A2 BRPI0910259A2 BRPI0910259A BRPI0910259A BRPI0910259A2 BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2 BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment methods
- inflammation treatment
- inflammation
- methods
- treatment
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3838108P | 2008-03-20 | 2008-03-20 | |
| US3937108P | 2008-03-25 | 2008-03-25 | |
| US4580708P | 2008-04-17 | 2008-04-17 | |
| US12109508P | 2008-12-09 | 2008-12-09 | |
| PCT/US2009/037887 WO2009117710A2 (en) | 2008-03-20 | 2009-03-20 | Methods of treating inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0910259A2 true BRPI0910259A2 (pt) | 2015-12-01 |
Family
ID=41091567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0910259A BRPI0910259A2 (pt) | 2008-03-20 | 2009-03-20 | métodos de tratamento de inflamação |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20110044988A1 (enExample) |
| EP (2) | EP2254597A4 (enExample) |
| JP (2) | JP2011515416A (enExample) |
| KR (1) | KR20110014141A (enExample) |
| CN (2) | CN102088993A (enExample) |
| AU (2) | AU2009225389A1 (enExample) |
| BR (1) | BRPI0910259A2 (enExample) |
| CA (2) | CA2717365A1 (enExample) |
| CO (1) | CO6300848A2 (enExample) |
| EA (1) | EA201001529A1 (enExample) |
| IL (1) | IL207752A0 (enExample) |
| MX (1) | MX2010010198A (enExample) |
| NZ (1) | NZ588033A (enExample) |
| WO (2) | WO2009117706A2 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2254597A4 (en) * | 2008-03-20 | 2012-04-18 | Carolus Therapeutics Inc | TREATMENT PROCEDURE WITH ANTI-MIF ANTIBODIES |
| CA2716628A1 (en) * | 2008-03-24 | 2009-10-01 | Carolus Therapeutics, Inc. | Methods and compositions for treating atherosclerosis and related conditions |
| WO2010056910A2 (en) * | 2008-11-12 | 2010-05-20 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
| WO2011038149A2 (en) * | 2009-09-23 | 2011-03-31 | Carolus Therapeutics, Inc. | Methods of treating inflammation |
| EP2308485A1 (en) | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Sulfonamides for the prevention of diabetes |
| EP2308484A1 (en) | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets |
| WO2012125680A1 (en) | 2011-03-16 | 2012-09-20 | Novartis Ag | Methods of treating vasculitis using an il-17 binding molecule |
| EP2696682B1 (en) * | 2011-04-13 | 2018-03-21 | Innovimmune Biotherapeutics, Inc. | Mif inhibitors and their uses |
| TWI407964B (zh) * | 2011-05-10 | 2013-09-11 | Univ Fu Jen Catholic | 干擾性核糖核酸用於治療或減緩疼痛之用途 |
| WO2012178137A1 (en) | 2011-06-24 | 2012-12-27 | Gillies Stephen D | Light chain immunoglobulin fusion proteins and methods of use thereof |
| US10596233B2 (en) | 2011-06-30 | 2020-03-24 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
| US9801921B2 (en) | 2011-06-30 | 2017-10-31 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
| WO2013010955A1 (en) | 2011-07-15 | 2013-01-24 | Morphosys Ag | Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt) |
| CN102357249A (zh) * | 2011-10-26 | 2012-02-22 | 广州赫尔氏药物开发有限公司 | 能够抑制耐药性结核杆菌的药物 |
| EP3338776A1 (en) | 2012-05-01 | 2018-06-27 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
| US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
| US10561676B2 (en) * | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
| EP3052526A4 (en) | 2013-10-03 | 2017-04-19 | Oregon Health & Science University | Recombinant polypeptides comprising mhc class ii 1 domains |
| EP3242685B1 (en) | 2015-01-09 | 2022-05-04 | AdAlta Limited | Cxcr4 binding molecules |
| TW201718851A (zh) * | 2015-09-18 | 2017-06-01 | 通用醫院公司 | 具有抗化學排斥(anti-fugetactic)性質之經修飾自然殺手細胞及其用途 |
| JP6958820B2 (ja) | 2015-12-14 | 2021-11-02 | エックス４ ファーマシューティカルズ， インコーポレイテッド | がんを処置する方法 |
| EP3389634B1 (en) | 2015-12-14 | 2021-10-06 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| AU2017231832B2 (en) | 2016-03-11 | 2021-11-11 | Ardea Biosciences, Inc. | CXCR-2 inhibitors for treating crystal arthropathy disorders |
| KR102645432B1 (ko) * | 2016-03-28 | 2024-03-11 | (주)아모레퍼시픽 | 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법 |
| WO2017177230A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| WO2017184683A1 (en) * | 2016-04-21 | 2017-10-26 | The Board Of Regents Of The University Of Taxas System | Methods and compositions for detecting aneurysms |
| NZ789594A (en) | 2016-06-20 | 2025-07-25 | Kymab Ltd | Anti-PD-L1 antibodies |
| CA3027500A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| EP3808748A1 (en) | 2016-06-21 | 2021-04-21 | X4 Pharmaceuticals, Inc. | Substituted piperidines as cxcr4-inhibitors |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| US11291641B2 (en) * | 2016-10-03 | 2022-04-05 | The Children's Medical Center Corporation | Prevention and treatment of diabetic nephropathy |
| CN108355133A (zh) * | 2017-01-26 | 2018-08-03 | 中国医学科学院阜外医院 | 靶向cxcr7的药物组合物和方法 |
| US11767564B2 (en) * | 2017-10-27 | 2023-09-26 | Board Of Regents, The University Of Texas System | Use of SDHA as a prognostic marker and therapeutic target in uveal melanoma |
| CN107964045B (zh) * | 2017-12-18 | 2021-04-23 | 南京医科大学 | 一种人鼠嵌合抗CXCR2全分子IgG及其应用 |
| AU2019252676A1 (en) | 2018-04-11 | 2020-11-26 | Ohio State Innovation Foundation | Methods and compositions for sustained release microparticles for ocular drug delivery |
| MX2020013155A (es) | 2018-06-05 | 2021-04-29 | Anji Pharma Us Llc | Composiciones y metodos para tratar la pancreatitis. |
| CA3098415A1 (en) * | 2018-06-07 | 2019-12-12 | Oncoone Research & Development Gmbh | Anti-oxmif/anti-cd3 antibody for cancer treatment |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| CA3123290A1 (en) * | 2018-12-26 | 2020-07-02 | Colgate-Palmolive Company | Biomarkers of neutrophil deregulation as diagnostic for gingivitis |
| CN110133306B (zh) * | 2019-05-09 | 2023-04-07 | 北京勤邦生物技术有限公司 | 检测西马特罗的酶联免疫试剂盒及其应用 |
| JP2023517956A (ja) | 2020-03-10 | 2023-04-27 | エックス４ ファーマシューティカルズ， インコーポレイテッド | 好中球減少症を処置する方法 |
| KR20220166809A (ko) * | 2020-03-11 | 2022-12-19 | 바이오라인알엑스 리미티드 | 급성 호흡곤란 증후군 및 바이러스 감염 치료를 위한 cxcr4 억제제 |
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| JP2024512499A (ja) * | 2021-03-22 | 2024-03-19 | クリップスビーエヌシー・カンパニー・リミテッド | 新規な組換えマイコバクテリウムスメグマチス菌株およびその用途 |
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| KR102561554B1 (ko) * | 2021-04-14 | 2023-07-28 | 부산대학교 산학협력단 | 치주질환 진단용 바이오마커 조성물, 치주질환 치료 효용성 평가용 바이오마커 조성물 및 이를 이용한 진단키트 |
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| EP1741779A3 (en) * | 1993-05-17 | 2010-03-24 | The Picower Institute For Medical Research | Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine mediated toxicity |
| US6030615A (en) * | 1993-05-17 | 2000-02-29 | The Picower Institute For Medical Research | Combination method for treating diseases caused by cytokine-mediated toxicity |
| US20070072861A1 (en) * | 2000-03-27 | 2007-03-29 | Barbara Roniker | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
| US20020114812A1 (en) * | 2001-01-12 | 2002-08-22 | Riichiro Abe | Methods and compositions for modulating regulation of the cytotoxic lymphocyte response by macrophage migration inhibitory factor |
| JP2003226653A (ja) * | 2001-11-30 | 2003-08-12 | Jun Nishihira | 多発性硬化症治療剤 |
| WO2003047622A1 (fr) * | 2001-11-30 | 2003-06-12 | Jun Nishihira | Remedes pour la sclerose en plaques |
| US6656168B2 (en) * | 2001-12-18 | 2003-12-02 | Kimberly-Clark Worldwide, Inc. | Feminine care product with discrete areas of a skin wellness additive |
| AU2003213647A1 (en) * | 2002-02-27 | 2003-09-09 | Emory University | Multimeric binding complexes |
| AU2003215732B2 (en) * | 2002-03-01 | 2009-12-17 | Immunomedics, Inc. | Internalizing anti-CD74 antibodies and methods of use |
| EP1569692B1 (en) * | 2002-11-25 | 2010-11-10 | Jallal Messadek | Betaine and salicylic acid compositions |
| TW200418829A (en) * | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
| US20050202010A1 (en) * | 2003-08-29 | 2005-09-15 | Giroir Brett P. | Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor |
| WO2005065328A2 (en) * | 2003-12-30 | 2005-07-21 | The United States Of America, As Represented By The Department Of Veterans Affairs | Macrophage migration inhibitory factor (mif) as marker for urological inflammatory disease |
| US20060257466A1 (en) * | 2005-04-06 | 2006-11-16 | Kim Perry M | Administration of macrophage targeted formulations of compounds which modulate cholesterol-metabolizing enzymes for treatment of atherosclerosis |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| WO2007138961A1 (ja) * | 2006-05-29 | 2007-12-06 | Redox Bioscience Inc. | マクロファージ遊走阻止因子によって引き起こされる障害の予防乃至治療剤 |
| EP2254597A4 (en) * | 2008-03-20 | 2012-04-18 | Carolus Therapeutics Inc | TREATMENT PROCEDURE WITH ANTI-MIF ANTIBODIES |
| CA2716628A1 (en) * | 2008-03-24 | 2009-10-01 | Carolus Therapeutics, Inc. | Methods and compositions for treating atherosclerosis and related conditions |
| WO2010056910A2 (en) * | 2008-11-12 | 2010-05-20 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
| US20110256130A1 (en) * | 2008-12-01 | 2011-10-20 | Joshua Robert Schultz | Methods of treating inflammatory disorders |
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2009
- 2009-03-20 EP EP09722541A patent/EP2254597A4/en not_active Withdrawn
- 2009-03-20 EP EP09721240A patent/EP2252318A4/en not_active Withdrawn
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- 2009-03-20 CN CN2009801093284A patent/CN102088993A/zh active Pending
- 2009-03-20 MX MX2010010198A patent/MX2010010198A/es active IP Right Grant
- 2009-03-20 NZ NZ588033A patent/NZ588033A/xx not_active IP Right Cessation
- 2009-03-20 CA CA2717365A patent/CA2717365A1/en not_active Abandoned
- 2009-03-20 US US12/918,968 patent/US20110044988A1/en not_active Abandoned
- 2009-03-20 AU AU2009225389A patent/AU2009225389A1/en not_active Abandoned
- 2009-03-20 EA EA201001529A patent/EA201001529A1/ru unknown
- 2009-03-20 CN CN200980109905XA patent/CN102046199A/zh active Pending
- 2009-03-20 BR BRPI0910259A patent/BRPI0910259A2/pt not_active IP Right Cessation
- 2009-03-20 US US12/918,964 patent/US20110262386A1/en not_active Abandoned
- 2009-03-20 KR KR1020107023480A patent/KR20110014141A/ko not_active Withdrawn
- 2009-03-20 WO PCT/US2009/037883 patent/WO2009117706A2/en not_active Ceased
- 2009-03-20 CA CA2717071A patent/CA2717071A1/en not_active Abandoned
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- 2009-03-20 WO PCT/US2009/037887 patent/WO2009117710A2/en not_active Ceased
- 2009-03-20 JP JP2011501003A patent/JP2011526244A/ja active Pending
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2010
- 2010-08-23 IL IL207752A patent/IL207752A0/en unknown
- 2010-09-20 CO CO10116141A patent/CO6300848A2/es not_active Application Discontinuation
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| CA2717365A1 (en) | 2009-09-24 |
| CA2717071A1 (en) | 2009-09-24 |
| CO6300848A2 (es) | 2011-07-21 |
| WO2009117706A3 (en) | 2010-01-21 |
| JP2011515416A (ja) | 2011-05-19 |
| EA201001529A1 (ru) | 2011-06-30 |
| JP2011526244A (ja) | 2011-10-06 |
| AU2009225389A1 (en) | 2009-09-24 |
| AU2009225385A1 (en) | 2009-09-24 |
| EP2252318A4 (en) | 2012-04-18 |
| IL207752A0 (en) | 2010-12-30 |
| EP2254597A2 (en) | 2010-12-01 |
| WO2009117710A2 (en) | 2009-09-24 |
| CN102046199A (zh) | 2011-05-04 |
| NZ588033A (en) | 2012-11-30 |
| EP2252318A2 (en) | 2010-11-24 |
| KR20110014141A (ko) | 2011-02-10 |
| WO2009117710A3 (en) | 2010-01-21 |
| CN102088993A (zh) | 2011-06-08 |
| WO2009117706A2 (en) | 2009-09-24 |
| US20110044988A1 (en) | 2011-02-24 |
| MX2010010198A (es) | 2010-12-21 |
| US20110262386A1 (en) | 2011-10-27 |
| EP2254597A4 (en) | 2012-04-18 |
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