JP2016517273A5 - - Google Patents
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- Publication number
- JP2016517273A5 JP2016517273A5 JP2016501598A JP2016501598A JP2016517273A5 JP 2016517273 A5 JP2016517273 A5 JP 2016517273A5 JP 2016501598 A JP2016501598 A JP 2016501598A JP 2016501598 A JP2016501598 A JP 2016501598A JP 2016517273 A5 JP2016517273 A5 JP 2016517273A5
- Authority
- JP
- Japan
- Prior art keywords
- aptamer
- deoxyuridine
- disease
- independently selected
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361782938P | 2013-03-14 | 2013-03-14 | |
| US61/782,938 | 2013-03-14 | ||
| US201361789244P | 2013-03-15 | 2013-03-15 | |
| US61/789,244 | 2013-03-15 | ||
| PCT/US2014/024669 WO2014159669A2 (en) | 2013-03-14 | 2014-03-12 | Aptamers that bind to il-6 and their use in treating or diagnosing il-6 mediated conditions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016517273A JP2016517273A (ja) | 2016-06-16 |
| JP2016517273A5 true JP2016517273A5 (enExample) | 2017-03-16 |
| JP6591392B2 JP6591392B2 (ja) | 2019-10-16 |
Family
ID=51625609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016501598A Active JP6591392B2 (ja) | 2013-03-14 | 2014-03-12 | Ｉｌ−６に結合するアプタマー及びｉｌ−６介在性状態の治療または診断におけるそれらの使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9206429B2 (enExample) |
| EP (1) | EP2970979B1 (enExample) |
| JP (1) | JP6591392B2 (enExample) |
| KR (1) | KR102242874B1 (enExample) |
| CN (3) | CN109439664B (enExample) |
| AU (1) | AU2014244534B2 (enExample) |
| CA (1) | CA2902186C (enExample) |
| ES (1) | ES2710723T3 (enExample) |
| SG (1) | SG11201507335QA (enExample) |
| WO (1) | WO2014159669A2 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104561013A (zh) * | 2015-01-05 | 2015-04-29 | 中国人民解放军南京军区福州总医院 | 基于高通量测序技术进行核酸适配体序列优化的方法 |
| CN105203763B (zh) * | 2015-11-15 | 2017-01-04 | 北京博奥医学检验所有限公司 | 一种口腔癌特异性检测的试剂盒 |
| US10927380B2 (en) * | 2016-07-01 | 2021-02-23 | Somalogic, Inc. | Oligonucleotides comprising modified nucleosides |
| CN107663220B (zh) * | 2016-07-27 | 2020-10-02 | 上海伯豪医学检验所有限公司 | 修饰碱基、包含修饰碱基的核酸、适配体及其应用 |
| CN110023499A (zh) | 2016-10-24 | 2019-07-16 | 拜欧亿思有限公司 | 肿瘤坏死因子-α(TNF-α)结合适配体及其治疗用途 |
| CN107238712B (zh) * | 2017-06-05 | 2018-12-28 | 中国人民解放军沈阳军区总医院 | 血浆s100a12在st段抬高型心肌梗死预后中的应用 |
| US12484814B2 (en) | 2018-10-02 | 2025-12-02 | WearOptimo Pty Ltd | Actuator system |
| US12569679B2 (en) | 2018-10-02 | 2026-03-10 | WearOptimo Pty Ltd | Treatment delivery system |
| WO2020069565A1 (en) | 2018-10-02 | 2020-04-09 | WearOptimo Pty Ltd | Measurement system |
| US11649460B2 (en) | 2020-03-20 | 2023-05-16 | Joao Francisco Peinado Pereira | DNA aptamers, method for inhibiting human galectin-1 and method of treating a mammal in need thereof |
| CN115851742B (zh) * | 2022-10-28 | 2025-10-10 | 合肥工业大学 | 一种IL-6/sIL-6R双特异性环状核酸适配体及试剂盒与应用 |
| IL324176B1 (en) * | 2023-04-26 | 2026-08-01 | Eurus Therapeutics Inc | Unnatural polynucleotides for targeted modification of nucleotide sequence |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070166741A1 (en) | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| CA2526853A1 (en) * | 2003-05-23 | 2005-03-03 | Board Of Regents - The University Of Texas System | Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer targeting ap-1 transcription factors |
| EP1756138A4 (en) * | 2004-03-05 | 2009-07-01 | Archemix Corp | APTAMERS FACILITATED TO THE FAMILY OF HUMAN IL-12 CYTOKINS AND THEIR USE AS THERAPEUTICS AGAINST AUTOIMMUNE DISEASES |
| HUE025489T2 (en) | 2006-01-17 | 2016-04-28 | Somalogic Inc | Multiplexed analysis of test samples |
| US7964356B2 (en) * | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US7855054B2 (en) | 2007-01-16 | 2010-12-21 | Somalogic, Inc. | Multiplexed analyses of test samples |
| US8975026B2 (en) * | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| ES3045958T3 (en) | 2007-07-17 | 2025-12-01 | Somalogic Operating Co Inc | Method for generating aptamers with improved off-rates |
| NZ602618A (en) * | 2010-04-12 | 2013-12-20 | Somalogic Inc | Aptamers to beta-ngf and their use in treating beta-ngf mediated diseases and disorders |
| US8658613B2 (en) | 2010-11-30 | 2014-02-25 | Otc Biotechnologies, Llc | Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health |
| FR2978964B1 (fr) * | 2011-08-09 | 2015-02-20 | Conservatoire Nat Arts | Composition vaccinale anti-il-6 |
-
2014
- 2014-03-12 SG SG11201507335QA patent/SG11201507335QA/en unknown
- 2014-03-12 CN CN201811220016.8A patent/CN109439664B/zh active Active
- 2014-03-12 KR KR1020157027953A patent/KR102242874B1/ko not_active Expired - Fee Related
- 2014-03-12 EP EP14775454.3A patent/EP2970979B1/en active Active
- 2014-03-12 JP JP2016501598A patent/JP6591392B2/ja active Active
- 2014-03-12 US US14/206,814 patent/US9206429B2/en active Active
- 2014-03-12 ES ES14775454T patent/ES2710723T3/es active Active
- 2014-03-12 CA CA2902186A patent/CA2902186C/en active Active
- 2014-03-12 CN CN202110252614.9A patent/CN112961860A/zh active Pending
- 2014-03-12 CN CN201480014093.1A patent/CN105051193A/zh active Pending
- 2014-03-12 AU AU2014244534A patent/AU2014244534B2/en not_active Ceased
- 2014-03-12 WO PCT/US2014/024669 patent/WO2014159669A2/en not_active Ceased
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