CN112961860A - 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途 - Google Patents

结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途 Download PDF

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CN112961860A
CN112961860A CN202110252614.9A CN202110252614A CN112961860A CN 112961860 A CN112961860 A CN 112961860A CN 202110252614 A CN202110252614 A CN 202110252614A CN 112961860 A CN112961860 A CN 112961860A
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aptamer
disease
seq
cancer
deoxyuridine
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Pending
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CN202110252614.9A
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Chinese (zh)
Inventor
沙希·古普塔
广田雅生
丹尼尔·J·施奈德
铃木智树
塞尔·C·贾维斯
石川优一
村上育郎
埃米·热利纳
希拉·沃
内博伊沙·亚尼奇
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Otsuka Pharmaceutical Co Ltd
Somalogic Inc
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Otsuka Pharmaceutical Co Ltd
Somalogic Inc
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Publication of CN112961860A publication Critical patent/CN112961860A/zh
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CN202110252614.9A 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途 Pending CN112961860A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361782938P 2013-03-14 2013-03-14
US61/782,938 2013-03-14
US201361789244P 2013-03-15 2013-03-15
US61/789,244 2013-03-15
CN201480014093.1A CN105051193A (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途

Related Parent Applications (1)

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CN201480014093.1A Division CN105051193A (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途

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CN112961860A true CN112961860A (zh) 2021-06-15

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CN202110252614.9A Pending CN112961860A (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途
CN201811220016.8A Active CN109439664B (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途
CN201480014093.1A Pending CN105051193A (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途

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CN201811220016.8A Active CN109439664B (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途
CN201480014093.1A Pending CN105051193A (zh) 2013-03-14 2014-03-12 结合il-6的适体及其在治疗或诊断il-6介导的疾患中的用途

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Country Link
US (1) US9206429B2 (enExample)
EP (1) EP2970979B1 (enExample)
JP (1) JP6591392B2 (enExample)
KR (1) KR102242874B1 (enExample)
CN (3) CN112961860A (enExample)
AU (1) AU2014244534B2 (enExample)
CA (1) CA2902186C (enExample)
ES (1) ES2710723T3 (enExample)
SG (1) SG11201507335QA (enExample)
WO (1) WO2014159669A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104561013A (zh) * 2015-01-05 2015-04-29 中国人民解放军南京军区福州总医院 基于高通量测序技术进行核酸适配体序列优化的方法
CN105891486A (zh) * 2015-11-15 2016-08-24 陈博 一种口腔癌特异性检测的试剂盒
CN109312346B (zh) * 2016-07-01 2024-07-30 私募蛋白质体操作有限公司 包含修饰核苷的寡核苷酸
CN107663220B (zh) * 2016-07-27 2020-10-02 上海伯豪医学检验所有限公司 修饰碱基、包含修饰碱基的核酸、适配体及其应用
WO2018079864A1 (ko) * 2016-10-24 2018-05-03 김성천 TNF-α 결합 압타머 및 그것의 치료적 용도
CN107238712B (zh) * 2017-06-05 2018-12-28 中国人民解放军沈阳军区总医院 血浆s100a12在st段抬高型心肌梗死预后中的应用
AU2019352635B2 (en) 2018-10-02 2024-12-19 WearOptimo Pty Ltd Actuator system
JP7379505B2 (ja) 2018-10-02 2023-11-14 ウェアオプティモ ピーティーワイ リミテッド 流体レベルの判定
US11649460B2 (en) 2020-03-20 2023-05-16 Joao Francisco Peinado Pereira DNA aptamers, method for inhibiting human galectin-1 and method of treating a mammal in need thereof
CN115851742B (zh) * 2022-10-28 2025-10-10 合肥工业大学 一种IL-6/sIL-6R双特异性环状核酸适配体及试剂盒与应用
KR20250168544A (ko) * 2023-04-26 2025-12-02 유러스 세러퓨틱스 가부시키가이샤 표적 뉴클레오티드 서열의 개변을 위한 비천연형 폴리뉴클레오티드

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070166741A1 (en) 1998-12-14 2007-07-19 Somalogic, Incorporated Multiplexed analyses of test samples
EP1667729A4 (en) 2003-05-23 2007-10-17 Univ Texas STRUCTURAL BASED AND COMBINATORY SELECTED OLIGONUCLEOSIDE PHOSPHOROTHIOAT AND PHOSPHORODITHIOAT APTAMIC TARGETING AP-1 TRANSCRIPTION FACTORS
EP1756138A4 (en) 2004-03-05 2009-07-01 Archemix Corp HUMAN CYTOKINE FAMILY BINDING APTAMERS AND THEIR USE AS THERAPEUTIC AGENTS OF AUTOIMMUNE DISEASES
DK1994171T3 (en) 2006-01-17 2015-06-15 Somalogic Inc Multiplex Analyses of test samples
US7964356B2 (en) 2007-01-16 2011-06-21 Somalogic, Inc. Method for generating aptamers with improved off-rates
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US8975026B2 (en) * 2007-01-16 2015-03-10 Somalogic, Inc. Method for generating aptamers with improved off-rates
CA2696431C (en) 2007-07-17 2021-01-05 Somalogic, Inc. Method for generating aptamers with improved off-rates
US20110275794A1 (en) * 2010-04-12 2011-11-10 Somalogic, Inc. 5-position modified pyrimidines and their use
US8658613B2 (en) 2010-11-30 2014-02-25 Otc Biotechnologies, Llc Methods and compositions of nucleic acid ligands for detection of clinical analytes related to human health
FR2978964B1 (fr) * 2011-08-09 2015-02-20 Conservatoire Nat Arts Composition vaccinale anti-il-6

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Publication number Publication date
SG11201507335QA (en) 2015-10-29
CN109439664B (zh) 2024-03-08
JP6591392B2 (ja) 2019-10-16
AU2014244534A1 (en) 2015-09-10
EP2970979A2 (en) 2016-01-20
HK1217512A1 (en) 2017-01-13
CN105051193A (zh) 2015-11-11
CA2902186A1 (en) 2014-10-02
EP2970979B1 (en) 2018-11-21
CN109439664A (zh) 2019-03-08
US9206429B2 (en) 2015-12-08
KR102242874B1 (ko) 2021-04-21
WO2014159669A3 (en) 2014-12-04
KR20150140669A (ko) 2015-12-16
US20140315986A1 (en) 2014-10-23
AU2014244534B2 (en) 2020-04-30
WO2014159669A2 (en) 2014-10-02
CA2902186C (en) 2023-04-11
EP2970979A4 (en) 2016-11-09
ES2710723T3 (es) 2019-04-26
JP2016517273A (ja) 2016-06-16

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