|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
EP0308020A3
(en)
|
1987-09-18 |
1990-12-05 |
Merck & Co. Inc. |
5-(aryl and heteroaryl)-6-(aryl and heteroaryl)-1,2-dihydro-2-oxo 3-pyridinecarboxylic acids and derivatives thereof
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5554630A
(en)
|
1993-03-24 |
1996-09-10 |
Neurosearch A/S |
Benzimidazole compounds
|
|
DE69524598T2
(de)
|
1994-06-20 |
2002-07-11 |
Takeda Chemical Industries, Ltd. |
Kondensierte imidazolderivate, ihre herstellung und verwendung
|
|
JPH11505524A
(ja)
|
1995-05-01 |
1999-05-21 |
藤沢薬品工業株式会社 |
イミダゾ１，２−ａピリジンおよびイミダゾ１，２−ａピリデジン誘導体、および骨吸収阻害剤としてのその用途
|
|
EP0951541B1
(en)
|
1995-07-31 |
2005-11-30 |
Urocor, Inc. |
Biomarkers and targets for diagnosis, prognosis and management of prostate disease
|
|
US6218529B1
(en)
|
1995-07-31 |
2001-04-17 |
Urocor, Inc. |
Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
|
|
AU6966696A
(en)
|
1995-10-05 |
1997-04-28 |
Warner-Lambert Company |
Method for treating and preventing inflammation and atherosclerosis
|
|
HU229024B1
(en)
|
1996-07-24 |
2013-07-29 |
Bristol Myers Squibb Pharma Co |
Azolo-pyridimidines, pharmaceutical compositions containing the same and use thereof
|
|
JP2002501532A
(ja)
|
1997-05-30 |
2002-01-15 |
メルク エンド カンパニー インコーポレーテッド |
新規血管形成阻害薬
|
|
US5990146A
(en)
|
1997-08-20 |
1999-11-23 |
Warner-Lambert Company |
Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation
|
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
ATE301657T1
(de)
|
1998-01-28 |
2005-08-15 |
Bristol Myers Squibb Pharma Co |
Azolo-pyrimidine
|
|
CA2341409A1
(en)
|
1998-08-31 |
2000-03-09 |
Merck And Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6245759B1
(en)
*
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
EP1194152A4
(en)
|
1999-06-30 |
2002-11-06 |
Merck & Co Inc |
Links to SRC kinase inhibition
|
|
EP1206260A4
(en)
|
1999-06-30 |
2002-10-30 |
Merck & Co Inc |
SRC-KINASE INHIBITING COMPOUNDS
|
|
WO2001000213A1
(en)
|
1999-06-30 |
2001-01-04 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
JP2001057292A
(ja)
|
1999-08-20 |
2001-02-27 |
Toray Ind Inc |
発光素子
|
|
GB9919778D0
(en)
*
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
|
GB9921150D0
(en)
|
1999-09-07 |
1999-11-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1214330A1
(en)
|
1999-09-21 |
2002-06-19 |
LION Bioscience AG |
Benzimidazole derivatives and combinatorial libraries thereof
|
|
GB9927687D0
(en)
|
1999-11-23 |
2000-01-19 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2003525291A
(ja)
|
2000-03-01 |
2003-08-26 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
２，４−二置換チアゾリル誘導体
|
|
IL151517A0
(en)
|
2000-03-09 |
2003-04-10 |
Aventis Pharma Gmbh |
Therapeutic uses of ppar mediators
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
US7022711B2
(en)
|
2000-08-04 |
2006-04-04 |
Warner-Lambert Company |
2-(4-Pyridyl)amino-6-dialkoxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
|
|
AU2001295992A1
(en)
|
2000-10-24 |
2002-05-06 |
Sankyo Company Limited |
Imidazopyridine derivatives
|
|
GB0027561D0
(en)
|
2000-11-10 |
2000-12-27 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2002046168A1
(en)
|
2000-12-07 |
2002-06-13 |
Astrazeneca Ab |
Therapeutic benzimidazole compounds
|
|
US20020107262A1
(en)
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
SE0100568D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
SE0100567D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
ES2316546T3
(es)
|
2001-02-20 |
2009-04-16 |
Astrazeneca Ab |
2-arilamino-pirimidinas para el tratamiento de trastornos asociados a gsk3.
|
|
TWI248936B
(en)
|
2001-03-21 |
2006-02-11 |
Merck Sharp & Dohme |
Imidazo-pyrimidine derivatives as ligands for GABA receptors
|
|
DE10117183A1
(de)
|
2001-04-05 |
2002-10-10 |
Gruenenthal Gmbh |
Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
|
|
US7074801B1
(en)
|
2001-04-26 |
2006-07-11 |
Eisai Co., Ltd. |
Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof
|
|
AU2002317377A1
(en)
|
2001-07-20 |
2003-03-03 |
Cancer Research Technology Limited |
Biphenyl apurinic/apyrimidinic site endonuclease inhibitors to treat cancer
|
|
GB0128499D0
(en)
|
2001-11-28 |
2002-01-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6900208B2
(en)
|
2002-03-28 |
2005-05-31 |
Bristol Myers Squibb Company |
Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
|
|
US7662826B2
(en)
|
2002-04-23 |
2010-02-16 |
Shionogi & Co., Ltd. |
Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same
|
|
JP2004002826A
(ja)
|
2002-04-24 |
2004-01-08 |
Sankyo Co Ltd |
高分子イミダゾピリジン誘導体
|
|
ATE381332T1
(de)
|
2002-05-02 |
2008-01-15 |
Merck & Co Inc |
Tyrosinkinase-hemmer
|
|
AUPS251402A0
(en)
*
|
2002-05-23 |
2002-06-13 |
Cytopia Pty Ltd |
Kinase inhibitors
|
|
WO2003099811A1
(en)
|
2002-05-23 |
2003-12-04 |
Cytopia Pty Ltd |
Kinase inhibitors
|
|
GB0212048D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0212049D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU2003240488A1
(en)
|
2002-06-04 |
2003-12-19 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
|
|
US7196090B2
(en)
|
2002-07-25 |
2007-03-27 |
Warner-Lambert Company |
Kinase inhibitors
|
|
MY133311A
(en)
|
2002-09-19 |
2007-11-30 |
Schering Corp |
Novel imidazopyridines as cyclin dependent kinase inhibitors
|
|
GB0223349D0
(en)
|
2002-10-08 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2004035579A1
(ja)
|
2002-10-15 |
2004-04-29 |
Takeda Pharmaceutical Company Limited |
イミダゾピリジン誘導体、その製造法および用途
|
|
US7550470B2
(en)
|
2002-12-11 |
2009-06-23 |
Merck & Co. Inc. |
Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors
|
|
AU2003298942A1
(en)
|
2002-12-11 |
2004-06-30 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
|
WO2004075021A2
(en)
|
2003-02-14 |
2004-09-02 |
Vertex Pharmaceuticals, Inc. |
Molecular modeling methods
|
|
US7476670B2
(en)
|
2003-02-18 |
2009-01-13 |
Aventis Pharma S.A. |
Purine derivatives, method for preparing, pharmaceutical compositions and novel use
|
|
US7157460B2
(en)
|
2003-02-20 |
2007-01-02 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
|
WO2004087153A2
(en)
|
2003-03-28 |
2004-10-14 |
Chiron Corporation |
Use of organic compounds for immunopotentiation
|
|
JP4769720B2
(ja)
|
2003-08-21 |
2011-09-07 |
オーエスアイ・ファーマシューテイカルズ・エル・エル・シー |
Ｎ−置換ベンズイミダゾリルｃ−Ｋｉｔ阻害剤
|
|
US7442709B2
(en)
|
2003-08-21 |
2008-10-28 |
Osi Pharmaceuticals, Inc. |
N3-substituted imidazopyridine c-Kit inhibitors
|
|
MXPA06002019A
(es)
|
2003-08-21 |
2006-05-31 |
Osi Pharm Inc |
Imidazopiridinas n3 sustituidas inhibidoras de c_kit.
|
|
NZ545694A
(en)
|
2003-12-03 |
2010-04-30 |
Ym Bioscience Australia Pty Lt |
Azole-based kinase inhibitors
|
|
EP1711496A4
(en)
|
2004-01-28 |
2009-02-11 |
Smithkline Beecham Corp |
THIAZOLE COMPOUNDS
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
JPWO2005108399A1
(ja)
|
2004-05-10 |
2008-03-21 |
萬有製薬株式会社 |
イミダゾピリジン化合物
|
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
|
AU2005278292B2
(en)
|
2004-08-31 |
2011-09-08 |
Msd K.K. |
Novel substituted imidazole derivatives
|
|
KR20070057965A
(ko)
|
2004-09-21 |
2007-06-07 |
신타 파마슈티칼스 코프. |
염증 및 면역 관련 용도를 위한 화합물
|
|
WO2006038001A1
(en)
|
2004-10-06 |
2006-04-13 |
Celltech R & D Limited |
Aminopyrimidine derivatives as jnk inhibitors
|
|
CA2589770A1
(en)
|
2004-12-01 |
2006-06-08 |
Osi Pharmaceuticals, Inc. |
N-substituted benzimidazolyl c-kit inhibitors and combinatorial benzimidazole library
|
|
WO2006070943A1
(ja)
|
2004-12-28 |
2006-07-06 |
Takeda Pharmaceutical Company Limited |
縮合イミダゾール化合物およびその用途
|
|
WO2006070198A1
(en)
|
2004-12-30 |
2006-07-06 |
Astex Therapeutics Limited |
Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases
|
|
DOP2006000051A
(es)
|
2005-02-24 |
2006-08-31 |
Lilly Co Eli |
Inhibidores de vegf-r2 y métodos
|
|
WO2006094235A1
(en)
|
2005-03-03 |
2006-09-08 |
Sirtris Pharmaceuticals, Inc. |
Fused heterocyclic compounds and their use as sirtuin modulators
|
|
JP2008534689A
(ja)
|
2005-04-05 |
2008-08-28 |
ファーマコペイア， インコーポレイテッド |
免疫抑制のためのプリン及びイミダゾピリジン誘導体
|
|
FR2884821B1
(fr)
|
2005-04-26 |
2007-07-06 |
Aventis Pharma Sa |
Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
|
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
|
AR056556A1
(es)
|
2005-09-30 |
2007-10-10 |
Astrazeneca Ab |
Imidazo(1,2-a)piridina con actividad antiproliferacion celular
|
|
AU2007227210A1
(en)
|
2006-03-20 |
2007-09-27 |
Synta Pharmaceuticals Corp. |
Benzoimidazolyl-parazine compounds for inflammation and immune-related uses
|
|
AU2007230911A1
(en)
|
2006-03-23 |
2007-10-04 |
Synta Pharmaceuticals Corp. |
Benzimidazolyl-pyridine compounds for inflammation and immune-related uses
|
|
ITVA20060041A1
(it)
|
2006-07-05 |
2008-01-06 |
Dialectica Srl |
Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
|
|
TW200811134A
(en)
|
2006-07-12 |
2008-03-01 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
EP1882475A1
(en)
|
2006-07-26 |
2008-01-30 |
Novartis AG |
Method of treating disorders mediated by the fibroblast growth factor receptor
|
|
US7737149B2
(en)
|
2006-12-21 |
2010-06-15 |
Astrazeneca Ab |
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof
|
|
US8513276B2
(en)
|
2006-12-22 |
2013-08-20 |
Astex Therapeutics Limited |
Imidazo[1,2-a]pyridine compounds for use in treating cancer
|
|
US8131527B1
(en)
|
2006-12-22 |
2012-03-06 |
Astex Therapeutics Ltd. |
FGFR pharmacophore compounds
|
|
HRP20150642T1
(hr)
|
2006-12-22 |
2015-08-14 |
Astex Therapeutics Limited |
BICIKLIÄŚKE HETEROCIKLIÄŚKE TVARI KAO INHIBITORI FGFR-a
|
|
US7977336B2
(en)
|
2006-12-28 |
2011-07-12 |
Banyu Pharmaceutical Co. Ltd |
Aminopyrimidine derivatives as PLK1 inhibitors
|
|
NZ580327A
(en)
|
2007-04-03 |
2012-02-24 |
Array Biopharma Inc |
IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS
|
|
TWI519508B
(zh)
|
2007-06-12 |
2016-02-01 |
Achaogen Inc |
抗菌劑
|
|
CA2690192A1
(en)
|
2007-06-26 |
2008-12-31 |
Gilead Colorado, Inc. |
Imidazopyridinyl thiazolyl histone deacetylase inhibitors
|
|
GB0720038D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0720041D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New Compounds
|
|
GB0810902D0
(en)
|
2008-06-13 |
2008-07-23 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906470D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906472D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|