|
US4666828A
(en)
|
1984-08-15 |
1987-05-19 |
The General Hospital Corporation |
Test for Huntington's disease
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4801531A
(en)
|
1985-04-17 |
1989-01-31 |
Biotechnology Research Partners, Ltd. |
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
|
|
EP0308020A3
(en)
|
1987-09-18 |
1990-12-05 |
Merck & Co. Inc. |
5-(aryl and heteroaryl)-6-(aryl and heteroaryl)-1,2-dihydro-2-oxo 3-pyridinecarboxylic acids and derivatives thereof
|
|
US5272057A
(en)
|
1988-10-14 |
1993-12-21 |
Georgetown University |
Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
|
|
US5192659A
(en)
|
1989-08-25 |
1993-03-09 |
Genetype Ag |
Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
|
|
US5554630A
(en)
|
1993-03-24 |
1996-09-10 |
Neurosearch A/S |
Benzimidazole compounds
|
|
CA2191979A1
(en)
|
1994-06-20 |
1995-12-28 |
Muneo Takatani |
Condensed imidazole compounds, their production and use
|
|
AU5348396A
(en)
|
1995-05-01 |
1996-11-21 |
Fujisawa Pharmaceutical Co., Ltd. |
Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivati ves and their use as bone resorption inhibitors
|
|
US6218529B1
(en)
|
1995-07-31 |
2001-04-17 |
Urocor, Inc. |
Biomarkers and targets for diagnosis, prognosis and management of prostate, breast and bladder cancer
|
|
WO1997012613A1
(en)
|
1995-10-05 |
1997-04-10 |
Warner-Lambert Company |
Method for treating and preventing inflammation and atherosclerosis
|
|
AU747708B2
(en)
|
1996-07-24 |
2002-05-23 |
Du Pont Pharmaceuticals Company |
Azolo triazines and pyrimidines
|
|
CA2744096C
(en)
|
1996-07-31 |
2013-07-30 |
Laboratory Corporation Of America Holdings |
Biomarkers and targets for diagnosis, prognosis and management of prostate disease
|
|
CA2291709A1
(en)
|
1997-05-30 |
1998-12-03 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US5990146A
(en)
|
1997-08-20 |
1999-11-23 |
Warner-Lambert Company |
Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation
|
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
IL137019A0
(en)
|
1998-01-28 |
2001-06-14 |
Du Pont Pharm Co |
Azolo triazines and pyrimidines
|
|
CA2341409A1
(en)
|
1998-08-31 |
2000-03-09 |
Merck And Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6245759B1
(en)
*
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
EP1206265B1
(en)
|
1999-06-30 |
2003-11-12 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
WO2001000214A1
(en)
|
1999-06-30 |
2001-01-04 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
US6329380B1
(en)
|
1999-06-30 |
2001-12-11 |
Merck & Co., Inc. |
SRC kinase inhibitor compounds
|
|
JP2001057292A
(ja)
|
1999-08-20 |
2001-02-27 |
Toray Ind Inc |
発光素子
|
|
GB9919778D0
(en)
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
|
GB9921150D0
(en)
|
1999-09-07 |
1999-11-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1214330A1
(en)
|
1999-09-21 |
2002-06-19 |
LION Bioscience AG |
Benzimidazole derivatives and combinatorial libraries thereof
|
|
GB9927687D0
(en)
|
1999-11-23 |
2000-01-19 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2397661C
(en)
|
2000-03-01 |
2012-01-03 |
Janssen Pharmaceutica N.V. |
2,4-disubstituted thiazolyl derivatives
|
|
MXPA02007603A
(es)
|
2000-03-09 |
2003-02-24 |
Aventis Pharma Gmbh |
Usos terapeuticos de mediadores ppar.
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
JP2004519422A
(ja)
|
2000-08-04 |
2004-07-02 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
２−（４−ピリジル）アミノ−６−ジアルコキシフェニルピリド〔２，３−ｄ〕ピリミジン−７−オン
|
|
WO2002034748A1
(fr)
|
2000-10-24 |
2002-05-02 |
Sankyo Company, Limited |
Derives d'imidazopyridine
|
|
GB0027561D0
(en)
|
2000-11-10 |
2000-12-27 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2004515496A
(ja)
|
2000-12-07 |
2004-05-27 |
アストラゼネカ・アクチエボラーグ |
ベンズイミダゾール治療剤
|
|
US20020107262A1
(en)
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
SE0100568D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
BR0207096A
(pt)
|
2001-02-20 |
2004-01-20 |
Astrazeneca Ab |
Uso de um composto, compostos, formulação farmacêutica, e, método de tratamento e/ou profilaxia de condições associadas com a inibição de glicogênio sintase quinase-3
|
|
SE0100567D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
TWI248936B
(en)
|
2001-03-21 |
2006-02-11 |
Merck Sharp & Dohme |
Imidazo-pyrimidine derivatives as ligands for GABA receptors
|
|
DE10117183A1
(de)
|
2001-04-05 |
2002-10-10 |
Gruenenthal Gmbh |
Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
|
|
EP2048142A3
(en)
|
2001-04-26 |
2009-04-22 |
Eisai R&D Management Co., Ltd. |
Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof
|
|
AU2002317377A1
(en)
|
2001-07-20 |
2003-03-03 |
Cancer Research Technology Limited |
Biphenyl apurinic/apyrimidinic site endonuclease inhibitors to treat cancer
|
|
GB0128499D0
(en)
|
2001-11-28 |
2002-01-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6900208B2
(en)
|
2002-03-28 |
2005-05-31 |
Bristol Myers Squibb Company |
Pyrrolopyridazine compounds and methods of use thereof for the treatment of proliferative disorders
|
|
CA2483306A1
(en)
|
2002-04-23 |
2003-11-06 |
Shionogi & Co., Ltd. |
Pyrazolo[1,5-a]pyrimidine derivative and nad(p)h oxidase inhibitor containing the same
|
|
JP2004002826A
(ja)
|
2002-04-24 |
2004-01-08 |
Sankyo Co Ltd |
高分子イミダゾピリジン誘導体
|
|
US7125888B2
(en)
|
2002-05-02 |
2006-10-24 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
ATE457025T1
(de)
*
|
2002-05-23 |
2010-02-15 |
Cytopia Res Pty Ltd |
Kinaseinhibitoren
|
|
AUPS251402A0
(en)
*
|
2002-05-23 |
2002-06-13 |
Cytopia Pty Ltd |
Kinase inhibitors
|
|
GB0212048D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0212049D0
(en)
|
2002-05-24 |
2002-07-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2003101993A1
(en)
|
2002-06-04 |
2003-12-11 |
Neogenesis Pharmaceuticals, Inc. |
Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
|
|
US7196090B2
(en)
|
2002-07-25 |
2007-03-27 |
Warner-Lambert Company |
Kinase inhibitors
|
|
WO2004026867A2
(en)
|
2002-09-19 |
2004-04-01 |
Schering Corporation |
Imidazopyridines as cyclin dependent kinase inhibitors
|
|
GB0223349D0
(en)
|
2002-10-08 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2004035579A1
(ja)
|
2002-10-15 |
2004-04-29 |
Takeda Pharmaceutical Company Limited |
イミダゾピリジン誘導体、その製造法および用途
|
|
US7550470B2
(en)
|
2002-12-11 |
2009-06-23 |
Merck & Co. Inc. |
Substituted pyrazolo[1,5-A]pyrimidines as tyrosine kinase inhibitors
|
|
AU2003298942A1
(en)
|
2002-12-11 |
2004-06-30 |
Merck And Co., Inc. |
Tyrosine kinase inhibitors
|
|
US7826979B2
(en)
|
2003-02-14 |
2010-11-02 |
Vertex Pharmaceuticals Incorporated |
Method of modeling complex formation between a query ligan and a target molecule
|
|
US7476670B2
(en)
|
2003-02-18 |
2009-01-13 |
Aventis Pharma S.A. |
Purine derivatives, method for preparing, pharmaceutical compositions and novel use
|
|
US7157460B2
(en)
|
2003-02-20 |
2007-01-02 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
|
WO2004087153A2
(en)
|
2003-03-28 |
2004-10-14 |
Chiron Corporation |
Use of organic compounds for immunopotentiation
|
|
BRPI0413746A
(pt)
*
|
2003-08-21 |
2006-10-24 |
Osi Pharm Inc |
composto ou um seu n-óxido ou seu sal farmaceuticamente aceitável, composição, e, método de tratamento de distúrbio hiperproliferativo
|
|
AP2006003552A0
(en)
|
2003-08-21 |
2006-04-30 |
Osi Pharm Inc |
N3 - substituted imidazopyridine C-kit inhibitors.
|
|
US7442709B2
(en)
|
2003-08-21 |
2008-10-28 |
Osi Pharmaceuticals, Inc. |
N3-substituted imidazopyridine c-Kit inhibitors
|
|
GB2423083B
(en)
*
|
2003-12-03 |
2007-07-11 |
Cytopia Res Pty Ltd |
Azole-based kinase inhibitors
|
|
JP2007519720A
(ja)
|
2004-01-28 |
2007-07-19 |
スミスクライン ビーチャム コーポレーション |
チアゾール化合物
|
|
TW200530236A
(en)
|
2004-02-23 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Heteroaryl phenylurea
|
|
US7566781B2
(en)
|
2004-05-10 |
2009-07-28 |
Banyu Pharmaceutical Co., Ltd. |
Imidazopyridine compound
|
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
|
CA2577947A1
(en)
*
|
2004-08-31 |
2006-03-09 |
Banyu Pharmaceutical Co., Ltd. |
Novel substituted imidazole derivative
|
|
KR20070057965A
(ko)
|
2004-09-21 |
2007-06-07 |
신타 파마슈티칼스 코프. |
염증 및 면역 관련 용도를 위한 화합물
|
|
WO2006038001A1
(en)
|
2004-10-06 |
2006-04-13 |
Celltech R & D Limited |
Aminopyrimidine derivatives as jnk inhibitors
|
|
CA2589770A1
(en)
|
2004-12-01 |
2006-06-08 |
Osi Pharmaceuticals, Inc. |
N-substituted benzimidazolyl c-kit inhibitors and combinatorial benzimidazole library
|
|
JPWO2006070943A1
(ja)
|
2004-12-28 |
2008-06-12 |
武田薬品工業株式会社 |
縮合イミダゾール化合物およびその用途
|
|
EP1836188A1
(en)
|
2004-12-30 |
2007-09-26 |
Astex Therapeutics Limited |
Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases
|
|
DOP2006000051A
(es)
|
2005-02-24 |
2006-08-31 |
Lilly Co Eli |
Inhibidores de vegf-r2 y métodos
|
|
US7998974B2
(en)
|
2005-03-03 |
2011-08-16 |
Sirtris Pharmaceuticals, Inc. |
Fused heterocyclic compounds and their use as sirtuin modulators
|
|
BRPI0610514A2
(pt)
|
2005-04-05 |
2016-11-16 |
Pharmacopeia Inc |
composto, composição farmacêutica, e, método de tratamento de um distúrbio
|
|
FR2884821B1
(fr)
|
2005-04-26 |
2007-07-06 |
Aventis Pharma Sa |
Pyrrolopyridines substitues, compositions les contenant, procede de fabrication et utilisation
|
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
|
AU2006296386A1
(en)
|
2005-09-30 |
2007-04-05 |
Astrazeneca Ab |
Imidazo [1,2-a] pyridine having anti-cell-proliferation activity
|
|
CA2645434A1
(en)
|
2006-03-20 |
2007-09-27 |
Synta Pharmaceutical Corp. |
Benzoimidazolyl-parazine compounds for inflammation and immune-related uses
|
|
AU2007230911A1
(en)
|
2006-03-23 |
2007-10-04 |
Synta Pharmaceuticals Corp. |
Benzimidazolyl-pyridine compounds for inflammation and immune-related uses
|
|
ITVA20060041A1
(it)
|
2006-07-05 |
2008-01-06 |
Dialectica Srl |
Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
|
|
TW200811134A
(en)
|
2006-07-12 |
2008-03-01 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
EP1882475A1
(en)
|
2006-07-26 |
2008-01-30 |
Novartis AG |
Method of treating disorders mediated by the fibroblast growth factor receptor
|
|
US7737149B2
(en)
|
2006-12-21 |
2010-06-15 |
Astrazeneca Ab |
N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof
|
|
US8131527B1
(en)
|
2006-12-22 |
2012-03-06 |
Astex Therapeutics Ltd. |
FGFR pharmacophore compounds
|
|
CN101679408B
(zh)
|
2006-12-22 |
2016-04-27 |
Astex治疗学有限公司 |
作为fgfr抑制剂的双环杂环化合物
|
|
JP5442449B2
(ja)
*
|
2006-12-22 |
2014-03-12 |
アステックス、セラピューティックス、リミテッド |
新規化合物
|
|
US7977336B2
(en)
|
2006-12-28 |
2011-07-12 |
Banyu Pharmaceutical Co. Ltd |
Aminopyrimidine derivatives as PLK1 inhibitors
|
|
UA101611C2
(ru)
|
2007-04-03 |
2013-04-25 |
Аррей Байофарма Инк. |
СОЕДИНЕНИЯ ИМИДАЗО[1,2-а]ПИРИДИНА КАК ИНГИБИТОРЫ ТИРОЗИНКИНАЗЫ РЕЦЕПТОРОВ
|
|
CA2691987C
(en)
|
2007-06-12 |
2016-08-16 |
Achaogen, Inc. |
Antibacterial agents
|
|
WO2009002534A1
(en)
|
2007-06-26 |
2008-12-31 |
Gilead Colorado, Inc. |
Imidazopyridinyl thiazolyl histone deacetylase inhibitors
|
|
GB0720041D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New Compounds
|
|
GB0720038D0
(en)
|
2007-10-12 |
2007-11-21 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0810902D0
(en)
|
2008-06-13 |
2008-07-23 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906470D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|
|
GB0906472D0
(en)
|
2009-04-15 |
2009-05-20 |
Astex Therapeutics Ltd |
New compounds
|