CY1117820T1 - Δικυκλικες ετερο-κυκλικες ενωσεις σαν καταστολεις κινασης (kinase) πρωτεϊνης - Google Patents

Δικυκλικες ετερο-κυκλικες ενωσεις σαν καταστολεις κινασης (kinase) πρωτεϊνης

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Publication number
CY1117820T1
CY1117820T1 CY20161100727T CY161100727T CY1117820T1 CY 1117820 T1 CY1117820 T1 CY 1117820T1 CY 20161100727 T CY20161100727 T CY 20161100727T CY 161100727 T CY161100727 T CY 161100727T CY 1117820 T1 CY1117820 T1 CY 1117820T1
Authority
CY
Cyprus
Prior art keywords
cyclotic
compounds
hydro
kinase proteins
kinase
Prior art date
Application number
CY20161100727T
Other languages
English (en)
Inventor
Gordon Saxty
Valerio Berdini
Christopher William Murray
Charlotte Mary Griffiths-Jones
Emma Vickerstaffe
Gilbert Ebai Besong
Original Assignee
Astex Therapeutics Limited
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Filing date
Publication date
Application filed by Astex Therapeutics Limited filed Critical Astex Therapeutics Limited
Publication of CY1117820T1 publication Critical patent/CY1117820T1/el

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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Abstract

Η εφεύρεση σχετίζεται με νέα δικυκλικά έτερο-κυκλικά παράγωγα του τύπου (Ι), όπου τα R1, q, Α, Β, X1, Χ2, Χ3, Χ4, Χ5 και R2 είναι όπως ορίζονται στην παρούσα, με φαρμακευτικές συνθέσεις που περιέχουν τις εν λόγω ενώσεις και την χρήση των εν λόγω ενώσεων στην θεραπεία ασθενειών, π.χ. καρκίνου.
CY20161100727T 2007-10-12 2016-07-25 Δικυκλικες ετερο-κυκλικες ενωσεις σαν καταστολεις κινασης (kinase) πρωτεϊνης CY1117820T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97958907P 2007-10-12 2007-10-12
GBGB0720038.9A GB0720038D0 (en) 2007-10-12 2007-10-12 New compounds
US6117208P 2008-06-13 2008-06-13
PCT/GB2008/003439 WO2009047522A1 (en) 2007-10-12 2008-10-10 Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
CY1117820T1 true CY1117820T1 (el) 2017-05-17

Family

ID=38788130

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100727T CY1117820T1 (el) 2007-10-12 2016-07-25 Δικυκλικες ετερο-κυκλικες ενωσεις σαν καταστολεις κινασης (kinase) πρωτεϊνης

Country Status (17)

Country Link
US (2) US8071614B2 (el)
EP (1) EP2203449B1 (el)
JP (1) JP5562858B2 (el)
AU (1) AU2008309342C1 (el)
CA (1) CA2701868C (el)
CY (1) CY1117820T1 (el)
ES (1) ES2585352T3 (el)
GB (1) GB0720038D0 (el)
HK (1) HK1145496A1 (el)
HR (1) HRP20160852T1 (el)
HU (1) HUE028999T2 (el)
ME (1) ME02815B (el)
PL (1) PL2203449T3 (el)
PT (1) PT2203449T (el)
RS (1) RS55045B1 (el)
SI (1) SI2203449T1 (el)
WO (1) WO2009047522A1 (el)

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