|
US4200750A
(en)
|
1977-01-07 |
1980-04-29 |
Westwood Pharmaceuticals Inc. |
4-Substituted imidazo [1,2-a]quinoxalines
|
|
DE3919348A1
(de)
|
1988-06-16 |
1989-12-21 |
Ciba Geigy Ag |
Mikrobizide mittel
|
|
MX16687A
(es)
|
1988-07-07 |
1994-01-31 |
Ciba Geigy Ag |
Compuestos de biarilo y procedimiento para su preparacion.
|
|
EP0430033A3
(en)
|
1989-11-24 |
1991-09-11 |
Ciba-Geigy Ag |
Microbicidal agents
|
|
GB9119920D0
(en)
|
1991-09-18 |
1991-10-30 |
Glaxo Group Ltd |
Chemical compounds
|
|
ES2162792T3
(es)
|
1991-09-18 |
2002-01-16 |
Glaxo Group Ltd |
Derivados de benzanilida como antagonistas de 5-ht1d.
|
|
GB9816837D0
(en)
|
1998-08-04 |
1998-09-30 |
Zeneca Ltd |
Amide derivatives
|
|
US5246943A
(en)
|
1992-05-19 |
1993-09-21 |
Warner-Lambert Company |
Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
|
|
US5236934A
(en)
|
1992-08-26 |
1993-08-17 |
E. I. Du Pont De Nemours And Company |
1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
|
|
GB2273930A
(en)
|
1992-12-30 |
1994-07-06 |
Glaxo Group Ltd |
Benzanilide derivatives
|
|
TW240217B
(enExample)
|
1992-12-30 |
1995-02-11 |
Glaxo Group Ltd |
|
|
IL108630A0
(en)
|
1993-02-18 |
1994-05-30 |
Fmc Corp |
Insecticidal substituted 2,4-diaminoquinazolines
|
|
GB2276162A
(en)
|
1993-03-17 |
1994-09-21 |
Glaxo Group Ltd |
Aniline and benazilide derivatives
|
|
GB2276161A
(en)
|
1993-03-17 |
1994-09-21 |
Glaxo Group Ltd |
Aniline and benzanilide derivatives
|
|
CN1129933A
(zh)
|
1993-08-31 |
1996-08-28 |
辉瑞大药厂 |
5-芳基吲哚衍生物
|
|
WO1995006644A1
(en)
|
1993-09-03 |
1995-03-09 |
Smithkline Beecham Plc |
Amide derivatives as 5ht1d receptor antagonists
|
|
JPH09503773A
(ja)
|
1993-10-19 |
1997-04-15 |
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー |
5ht−1dレセプター拮抗剤用のベンズアニリド誘導体
|
|
WO1995015954A1
(en)
*
|
1993-12-07 |
1995-06-15 |
Smithkline Beecham Plc |
Heterocyclic biphenylylamides useful as 5ht1d antagonists
|
|
GB9326008D0
(en)
|
1993-12-21 |
1994-02-23 |
Smithkline Beecham Plc |
Novel compounds
|
|
GB9408577D0
(en)
|
1994-04-29 |
1994-06-22 |
Fujisawa Pharmaceutical Co |
New compound
|
|
JPH09512804A
(ja)
|
1994-05-06 |
1997-12-22 |
スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー |
5−ht1dアンタゴニストとして有用なビフェニルカルボキシアミド類
|
|
US5521213A
(en)
|
1994-08-29 |
1996-05-28 |
Merck Frosst Canada, Inc. |
Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2
|
|
GB2295387A
(en)
|
1994-11-23 |
1996-05-29 |
Glaxo Inc |
Quinazoline antagonists of alpha 1c adrenergic receptors
|
|
WO1996031509A1
(en)
|
1995-04-04 |
1996-10-10 |
Glaxo Group Limited |
IMIDAZO[1,2-a]PYRIDINE DERIVATIVES
|
|
GB9507203D0
(en)
|
1995-04-07 |
1995-05-31 |
Smithkline Beecham Plc |
Novel compounds
|
|
IL118544A
(en)
|
1995-06-07 |
2001-08-08 |
Smithkline Beecham Corp |
History of imidazole, the process for their preparation and the pharmaceutical preparations containing them
|
|
WO1997003034A2
(en)
|
1995-07-10 |
1997-01-30 |
The Dow Chemical Company |
Polynitrile oxides
|
|
US6174887B1
(en)
|
1995-08-22 |
2001-01-16 |
Japan Tobacco Inc. |
Amide compounds and use of the same
|
|
US6323227B1
(en)
|
1996-01-02 |
2001-11-27 |
Aventis Pharmaceuticals Products Inc. |
Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
|
|
US6080767A
(en)
|
1996-01-02 |
2000-06-27 |
Aventis Pharmaceuticals Products Inc. |
Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides
|
|
PL187516B1
(pl)
|
1996-01-11 |
2004-07-30 |
Smithkline Beecham Corp |
Nowe podstawione pochodne imidazolu, sposób ich wytwarzania oraz kompozycja farmaceutyczna zawierająca te związki
|
|
FR2754260B1
(fr)
|
1996-10-04 |
1998-10-30 |
Adir |
Nouveaux derives substitues de biphenyle ou de phenylpyridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
US6147080A
(en)
|
1996-12-18 |
2000-11-14 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of p38
|
|
US5945418A
(en)
|
1996-12-18 |
1999-08-31 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of p38
|
|
EP0983260A2
(en)
|
1997-05-22 |
2000-03-08 |
G.D. Searle & Co. |
3(5)-HETEROARYL SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS
|
|
US6087496A
(en)
|
1998-05-22 |
2000-07-11 |
G. D. Searle & Co. |
Substituted pyrazoles suitable as p38 kinase inhibitors
|
|
CA2294057A1
(en)
|
1997-06-13 |
1998-12-17 |
Smithkline Beecham Corporation |
Novel pyrazole and pyrazoline substituted compounds
|
|
WO1998057934A1
(en)
|
1997-06-19 |
1998-12-23 |
The Du Pont Merck Pharmaceutical Company |
(AMIDINO)6-MEMBERED AROMATICS AS FACTOR Xa INHIBITORS
|
|
US6060491A
(en)
|
1997-06-19 |
2000-05-09 |
Dupont Pharmaceuticals |
6-membered aromatics as factor Xa inhibitors
|
|
AU8381098A
(en)
|
1997-07-02 |
1999-01-25 |
Smithkline Beecham Corporation |
Novel cycloalkyl substituted imidazoles
|
|
WO1999012930A1
(en)
|
1997-09-05 |
1999-03-18 |
Glaxo Group Limited |
2,3-diaryl-pyrazolo[1,5-b]pyridazines derivatives, their prepa ration and their use as cyclooxygenase 2 (cox-2) inhibitors
|
|
CA2304713C
(en)
*
|
1997-10-14 |
2003-06-10 |
Asahi Kasei Kogyo Kabushiki Kaisha |
Biphenyl-5-alkanoic acid derivatives and use thereof
|
|
EP1616865A1
(en)
*
|
1997-12-22 |
2006-01-18 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
|
JPH11218884A
(ja)
|
1998-02-03 |
1999-08-10 |
Konica Corp |
ハロゲン化銀写真感光材料
|
|
DE19817461A1
(de)
|
1998-04-20 |
1999-10-21 |
Basf Ag |
Neue substituierte Benzamide, deren Herstellung und Anwendung
|
|
US6579872B1
(en)
|
1998-05-15 |
2003-06-17 |
Astrazeneca Ab |
Bezamide derivatives for the treatment of diseases mediated by cytokines
|
|
US6867209B1
(en)
|
1998-05-22 |
2005-03-15 |
Scios, Inc. |
Indole-type derivatives as inhibitors of p38 kinase
|
|
US6130235A
(en)
|
1998-05-22 |
2000-10-10 |
Scios Inc. |
Compounds and methods to treat cardiac failure and other disorders
|
|
US6448257B1
(en)
|
1998-05-22 |
2002-09-10 |
Scios, Inc. |
Compounds and methods to treat cardiac failure and other disorders
|
|
WO2000012074A2
(en)
|
1998-08-28 |
2000-03-09 |
Scios Inc. |
Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase
|
|
US6184226B1
(en)
|
1998-08-28 |
2001-02-06 |
Scios Inc. |
Quinazoline derivatives as inhibitors of P-38 α
|
|
WO2000017175A1
(en)
|
1998-09-18 |
2000-03-30 |
Vertex Pharmaceuticals Incorporated |
INHIBITORS OF p38
|
|
PL348208A1
(en)
|
1998-11-03 |
2002-05-06 |
Glaxo Group Ltd |
Pyrazolopyridine derivatives as selective cox-2 inhibitors
|
|
EP1140840B1
(en)
|
1999-01-13 |
2006-03-22 |
Bayer Pharmaceuticals Corp. |
-g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
CA2361428A1
(en)
|
1999-02-11 |
2000-08-17 |
Cor Therapeutics, Inc. |
Inhibitors of factor xa
|
|
EP1157025B1
(en)
|
1999-02-27 |
2004-03-10 |
Glaxo Group Limited |
Pyrazolopyridines
|
|
GB9906566D0
(en)
|
1999-03-23 |
1999-05-19 |
Zeneca Ltd |
Chemical compounds
|
|
US6509361B1
(en)
|
1999-05-12 |
2003-01-21 |
Pharmacia Corporation |
1,5-Diaryl substituted pyrazoles as p38 kinase inhibitors
|
|
HRP20010854A2
(en)
*
|
1999-05-21 |
2003-04-30 |
Scios Inc |
INDOLE-TYPE DERIVATIVES AS INHIBITORS OF p38 KINASE
|
|
CA2374820A1
(en)
|
1999-05-24 |
2000-11-30 |
Cor Therapeutics, Inc. |
Inhibitors of factor xa
|
|
AU5283900A
(en)
|
1999-05-24 |
2000-12-12 |
Cor Therapeutics, Inc. |
Inhibitors of factor xa
|
|
WO2000071510A2
(en)
|
1999-05-24 |
2000-11-30 |
Cor Therapeutics, Inc. |
INHIBITORS OF FACTOR Xa
|
|
DE19932571A1
(de)
|
1999-07-13 |
2001-01-18 |
Clariant Gmbh |
Verfahren zur Herstellung von Biarylen unter Palladophosphacyclobutan-Katalyse
|
|
GB9919778D0
(en)
|
1999-08-21 |
1999-10-27 |
Zeneca Ltd |
Chemical compounds
|
|
US6576632B1
(en)
|
1999-08-27 |
2003-06-10 |
Pfizer Inc |
Biaryl compounds useful as anticancer agents
|
|
GB9924092D0
(en)
|
1999-10-13 |
1999-12-15 |
Zeneca Ltd |
Pyrimidine derivatives
|
|
CZ20012494A3
(cs)
|
1999-11-10 |
2001-10-17 |
Ortho-Mcneil Pharmaceutical, Inc. |
Substituované 2-aryl-3-(heteroaryl)-imidazo[1,2-a]Pyrimidiny, způsob přípravy těchto sloučenin a farmaceutické kompozice obsahující tyto sloučeniny
|
|
JP2003528084A
(ja)
|
2000-03-22 |
2003-09-24 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
p38のインヒビター
|
|
AU5878101A
(en)
|
2000-05-18 |
2001-11-26 |
Daiichi Pharmaceutical Co., Ltd. |
Novel benzofuran derivatives
|
|
PE20020506A1
(es)
|
2000-08-22 |
2002-07-09 |
Glaxo Group Ltd |
Derivados de pirazol fusionados como inhibidores de la proteina cinasa
|
|
HUP0303897A2
(hu)
|
2000-11-17 |
2004-03-01 |
Bristol-Myers Squibb Company |
Eljárások p38 kinázzal összafüggő esetek kezelésére, kináz inhibitorokként alkalmazható pirrolotriazin vegyületek és ezeket tartalmazó gyógyszerkészítmények
|
|
DE10059418A1
(de)
|
2000-11-30 |
2002-06-20 |
Aventis Pharma Gmbh |
Ortho, meta-substituierte Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
|
DE10060807A1
(de)
|
2000-12-07 |
2002-06-20 |
Aventis Pharma Gmbh |
Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
|
DE10063008A1
(de)
|
2000-12-16 |
2002-06-20 |
Merck Patent Gmbh |
Carbonsäureamidderivate
|
|
DE10110749A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Substituierte Aminodicarbonsäurederivate
|
|
EE200300437A
(et)
|
2001-03-09 |
2004-02-16 |
Pfizer Products Inc. |
Triasolopüridiinid kui põletikuvastased ained
|
|
ES2332090T3
(es)
|
2001-04-06 |
2010-01-26 |
Biocryst Pharmaceuticals, Inc. |
Compuestos biarilicos como inhibidores de serina proteasa.
|
|
FR2824827B1
(fr)
|
2001-05-17 |
2004-02-13 |
Fournier Lab Sa |
Nouveaux derives de 5-phenyl-1h-indole antagoniste des recepteurs de l'interleukine-8
|
|
AR037233A1
(es)
|
2001-09-07 |
2004-11-03 |
Euro Celtique Sa |
Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento
|
|
GB0124848D0
(en)
|
2001-10-16 |
2001-12-05 |
Celltech R&D Ltd |
Chemical compounds
|
|
GB0124941D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124934D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124931D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124928D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124938D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124936D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124932D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
GB0124939D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
SI1474395T1
(sl)
|
2002-02-12 |
2008-02-29 |
Smithkline Beecham Corp |
Nikotinamidni derivati, uporabni kot inhibitorji p38
|
|
US20030225089A1
(en)
|
2002-04-10 |
2003-12-04 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
|
|
GB0209891D0
(en)
|
2002-04-30 |
2002-06-05 |
Glaxo Group Ltd |
Novel compounds
|
|
GB0217757D0
(en)
|
2002-07-31 |
2002-09-11 |
Glaxo Group Ltd |
Novel compounds
|
|
US20040116479A1
(en)
|
2002-10-04 |
2004-06-17 |
Fortuna Haviv |
Method of inhibiting angiogenesis
|
|
US7136850B2
(en)
|
2002-12-20 |
2006-11-14 |
International Business Machines Corporation |
Self tuning database retrieval optimization using regression functions
|
|
CA2415049A1
(en)
*
|
2002-12-23 |
2004-06-23 |
William J. Wagner |
Windshield wiper blade slapper apparatus
|
|
GB0308201D0
(en)
|
2003-04-09 |
2003-05-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0308185D0
(en)
|
2003-04-09 |
2003-05-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0308186D0
(en)
|
2003-04-09 |
2003-05-14 |
Smithkline Beecham Corp |
Novel compounds
|
|
US7754726B2
(en)
|
2003-07-25 |
2010-07-13 |
Novartis Ag |
Benzamide derivatives as p-38 kinase inhibitors
|
|
GB0318814D0
(en)
|
2003-08-11 |
2003-09-10 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0402138D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0402140D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0402143D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
|
GB0402137D0
(en)
|
2004-01-30 |
2004-03-03 |
Smithkline Beecham Corp |
Novel compounds
|
|
AR055271A1
(es)
|
2004-10-05 |
2007-08-15 |
Smithkline Beecham Corp |
Compuesto del acido bifenil carboxilico, composicion farmaceutica que lo comprende, su uso para preparar esta ultima y proceso para prepararlo
|