ES2305317T3 - Derivados de amida bifenilcarboxilico como inhibidores de quinasa p38. - Google Patents

Derivados de amida bifenilcarboxilico como inhibidores de quinasa p38. Download PDF

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Publication number
ES2305317T3
ES2305317T3 ES02782928T ES02782928T ES2305317T3 ES 2305317 T3 ES2305317 T3 ES 2305317T3 ES 02782928 T ES02782928 T ES 02782928T ES 02782928 T ES02782928 T ES 02782928T ES 2305317 T3 ES2305317 T3 ES 2305317T3
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Prior art keywords
methyl
biphenyl
carbonyl
alkyl
amino
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Expired - Lifetime
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ES02782928T
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English (en)
Spanish (es)
Inventor
Richard Martyn c/o GlaxoSmithKline ANGELL
Nicola Mary c/o GlaxoSmithKline ASTON
Paul c/o GlaxoSmithKline BAMBOROUGH
Mark James c/o GlaxoSmithKline BAMFORD
George Stuart c/o GlaxoSmithKline COCKERILL
Stephen Sean c/o GlaxoSmithKline FLACK
Dramane Ibrahim c/o GlaxoSmithKline LAINE
Ann Louise c/o GlaxoSmithKline WALKER
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Glaxo Group Ltd
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Glaxo Group Ltd
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    • C07—ORGANIC CHEMISTRY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
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    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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ES02782928T 2001-10-17 2002-10-16 Derivados de amida bifenilcarboxilico como inhibidores de quinasa p38. Expired - Lifetime ES2305317T3 (es)

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Application Number Priority Date Filing Date Title
GB0124933 2001-10-17
GBGB0124933.3A GB0124933D0 (en) 2001-10-17 2001-10-17 Chemical compounds

Publications (1)

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ES2305317T3 true ES2305317T3 (es) 2008-11-01

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ES02782928T Expired - Lifetime ES2305317T3 (es) 2001-10-17 2002-10-16 Derivados de amida bifenilcarboxilico como inhibidores de quinasa p38.

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US (2) US7151118B2 (enExample)
EP (1) EP1436272B1 (enExample)
JP (1) JP2005508967A (enExample)
AT (1) ATE394383T1 (enExample)
DE (1) DE60226469D1 (enExample)
ES (1) ES2305317T3 (enExample)
GB (1) GB0124933D0 (enExample)
WO (1) WO2003033483A1 (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
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PE20020506A1 (es) * 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0124936D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124939D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124941D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124932D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124934D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124938D0 (en) 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
GB0124931D0 (en) * 2001-10-17 2001-12-05 Glaxo Group Ltd Chemical compounds
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