JP2011125348A5 - - Google Patents

Download PDF

Info

Publication number
JP2011125348A5
JP2011125348A5 JP2011036102A JP2011036102A JP2011125348A5 JP 2011125348 A5 JP2011125348 A5 JP 2011125348A5 JP 2011036102 A JP2011036102 A JP 2011036102A JP 2011036102 A JP2011036102 A JP 2011036102A JP 2011125348 A5 JP2011125348 A5 JP 2011125348A5
Authority
JP
Japan
Prior art keywords
perfusion culture
cells
present
animal cells
cell density
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011036102A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011125348A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2011125348A publication Critical patent/JP2011125348A/ja
Publication of JP2011125348A5 publication Critical patent/JP2011125348A5/ja
Pending legal-status Critical Current

Links

JP2011036102A 2004-03-05 2011-02-22 連続的灌流および交互接線流による細胞培養の方法 Pending JP2011125348A (ja)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP04075703.1 2004-03-05
EP04075702.3 2004-03-05
EP04075703 2004-03-05
EP04075702 2004-03-05
EP04077656 2004-09-27
EP04077657.7 2004-09-27
EP04077656.9 2004-09-27
EP04077657 2004-09-27

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007501239A Division JP2007525984A (ja) 2004-03-05 2005-03-04 連続的灌流および交互接線流による細胞培養の方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015209828A Division JP2016039817A (ja) 2004-03-05 2015-10-26 連続的灌流および交互接線流による細胞培養の方法

Publications (2)

Publication Number Publication Date
JP2011125348A JP2011125348A (ja) 2011-06-30
JP2011125348A5 true JP2011125348A5 (enExample) 2013-06-27

Family

ID=34961830

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2007501239A Pending JP2007525984A (ja) 2004-03-05 2005-03-04 連続的灌流および交互接線流による細胞培養の方法
JP2011036102A Pending JP2011125348A (ja) 2004-03-05 2011-02-22 連続的灌流および交互接線流による細胞培養の方法
JP2011259168A Pending JP2012090632A (ja) 2004-03-05 2011-11-28 連続的灌流および交互接線流による細胞培養の方法
JP2014016778A Expired - Fee Related JP5719947B2 (ja) 2004-03-05 2014-01-31 灌流培養方法の、細胞培養物中の細胞の凝集度合いを減少させるための使用
JP2015209828A Pending JP2016039817A (ja) 2004-03-05 2015-10-26 連続的灌流および交互接線流による細胞培養の方法
JP2017132997A Pending JP2017225443A (ja) 2004-03-05 2017-07-06 連続的灌流および交互接線流による細胞培養の方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2007501239A Pending JP2007525984A (ja) 2004-03-05 2005-03-04 連続的灌流および交互接線流による細胞培養の方法

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2011259168A Pending JP2012090632A (ja) 2004-03-05 2011-11-28 連続的灌流および交互接線流による細胞培養の方法
JP2014016778A Expired - Fee Related JP5719947B2 (ja) 2004-03-05 2014-01-31 灌流培養方法の、細胞培養物中の細胞の凝集度合いを減少させるための使用
JP2015209828A Pending JP2016039817A (ja) 2004-03-05 2015-10-26 連続的灌流および交互接線流による細胞培養の方法
JP2017132997A Pending JP2017225443A (ja) 2004-03-05 2017-07-06 連続的灌流および交互接線流による細胞培養の方法

Country Status (14)

Country Link
US (3) US8206981B2 (enExample)
EP (3) EP2540815A1 (enExample)
JP (6) JP2007525984A (enExample)
KR (1) KR101050585B1 (enExample)
CN (3) CN1930281A (enExample)
AU (1) AU2005229359C1 (enExample)
CA (1) CA2557046A1 (enExample)
DK (1) DK1720972T3 (enExample)
ES (1) ES2456015T3 (enExample)
IL (2) IL177724A (enExample)
PL (1) PL1720972T3 (enExample)
PT (1) PT1720972E (enExample)
SI (1) SI1720972T1 (enExample)
WO (1) WO2005095578A1 (enExample)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2456015T3 (es) 2004-03-05 2014-04-21 Dsm Ip Assets B.V. Procedimiento para cultivar células mediante perfusión continua y flujo tangencial alternante
WO2007097260A1 (ja) 2006-02-24 2007-08-30 Toray Industries, Inc. 化学品の製造方法、および、連続発酵装置
EP1870450A1 (en) * 2006-06-21 2007-12-26 DSMIP Assets B.V. Process for the culturing of E1-immortalized HER cells
AU2011211462C1 (en) * 2006-07-14 2015-01-22 Dpx Holdings B.V. Improved process for the culturing of cells
CN102876628A (zh) * 2006-07-14 2013-01-16 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
EP2014760A1 (en) 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
AU2008345231B2 (en) * 2007-12-27 2014-09-11 Takeda Pharmaceutical Company Limited Cell culture processes
WO2010003759A2 (en) * 2008-06-17 2010-01-14 Dsm Ip Assets B.V. Cell culturing method
EP3115451A1 (en) 2008-09-02 2017-01-11 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
DK2350268T3 (en) * 2008-11-03 2015-03-23 Crucell Holland Bv PROCEDURE FOR PRODUCING ADENOVIRUS VECTORS
KR101548790B1 (ko) 2009-07-16 2015-08-31 크루셀 홀란드 비.브이. 백신 제조를 위한 고역가 폴리오바이러스의 제조
WO2011045381A1 (en) 2009-10-15 2011-04-21 Crucell Holland B.V. Process for adenovirus purification from high cell density cultures
AU2010305765B2 (en) 2009-10-15 2015-07-02 Crucell Holland B.V. Method for the purification of adenovirus particles
NO2501822T3 (enExample) 2009-11-17 2018-01-13
US20120315696A1 (en) * 2010-02-15 2012-12-13 Alfred Luitjens METHOD FOR THE PRODUCTION OF Ad26 ADENOVIRAL VECTORS
JP5250155B2 (ja) * 2010-02-15 2013-07-31 クルセル ホランド ベー ヴェー Ａｄ２６アデノウイルスベクターの製造方法
WO2011144561A1 (en) 2010-05-18 2011-11-24 Crucell Holland B.V. Methods for welding ethylene vinyl acetate (eva) tubing, tubing obtained thereby and use of such tubing for sterile transfer of content into a bioreactor
CN107190034A (zh) * 2010-10-05 2017-09-22 诺沃—诺迪斯克保健股份有限公司 生产蛋白质的方法
US9115381B2 (en) * 2011-05-13 2015-08-25 Octapharma Ag Method of increasing the productivity of eucaryotic cells in the production of recombinant FVIII
KR20230114317A (ko) * 2011-07-01 2023-08-01 암젠 인크 포유동물 세포 배양
AR088381A1 (es) 2011-10-18 2014-05-28 Coherus Biosciences Inc Formulaciones de etanercept estabilizadas con meglumina
US10485869B2 (en) 2011-10-18 2019-11-26 Coherus Biosciences, Inc. Etanercept formulations stabilized with meglumine
CN103305417A (zh) * 2012-03-07 2013-09-18 无锡药明康德生物技术有限公司 进行蛋白生产的高产量反应器及其生产方法和应用
GB201211256D0 (en) * 2012-06-25 2012-08-08 Glaxosmithkline Biolog Sa Fermentation process
CA2878508A1 (en) 2012-07-09 2014-01-16 Coherus Biosciences, Inc. Etanercept formulations exhibiting marked reduction in sub-visible particles
SG11201501460RA (en) 2012-09-11 2015-04-29 Coherus Biosciences Inc Correctly folded etanercept in high purity and excellent yield
WO2014051503A1 (en) 2012-09-27 2014-04-03 Ge Healthcare Bio-Sciences Ab Tangential flow perfusion system
TWI637057B (zh) 2012-11-09 2018-10-01 拜爾沙納有限公司 具交替生物反應器用途之不連續進料批次製程
KR20210095233A (ko) * 2013-03-15 2021-07-30 젠자임 코포레이션 고-밀도 세포 뱅킹 방법
EP2976418B1 (en) 2013-03-19 2020-09-30 CMC Biologics A/S A method for producing a product (e.g. polypeptide) in a continuous cell culture fermentation process.
EP3391942A1 (en) 2013-03-26 2018-10-24 Coherus Biosciences, Inc. Protein production method
US9790465B2 (en) 2013-04-30 2017-10-17 Corning Incorporated Spheroid cell culture well article and methods thereof
SG10201803601SA (en) * 2013-09-16 2018-06-28 Genzyme Corp Methods and systems for processing a cell culture
BR112016006063A2 (pt) 2013-09-30 2017-08-01 Crucell Holland Bv método para clarificação de uma colheita de cultura celular em bruto
CN103525756B (zh) * 2013-10-23 2015-04-08 南京农业大学 一种原代鸡肝细胞的分离培养方法
EP3083933B1 (en) * 2013-12-20 2026-01-21 Biogen MA Inc. Use of perfusion seed cultures to improve biopharmaceutical fed-batch production capacity and product quality
IL282517B (en) * 2014-01-29 2022-07-01 Amgen Inc Overexpression of n-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
EP3107934A4 (en) * 2014-02-17 2017-10-18 Advantech Bioscience Farmacêutica Ltda Enhancement of recombinant protein expression using a membrane-based cell retention system
PT3926051T (pt) * 2014-06-04 2024-06-20 Amgen Inc Métodos de colheita de culturas de células de mamíferos
CN106574252B (zh) 2014-07-24 2021-06-01 扬森疫苗与预防公司 从细胞培养物中纯化脊髓灰质炎病毒的方法
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
CN107426990A (zh) * 2014-09-18 2017-12-01 建新公司 超高密度细胞建库方法
KR102460969B1 (ko) 2014-10-29 2022-10-31 코닝 인코포레이티드 세포 배양 인서트
CN107109339B (zh) 2014-10-29 2021-07-02 康宁股份有限公司 灌注生物反应器平台
WO2016069930A1 (en) 2014-10-29 2016-05-06 Corning Incorporated Microwell design and fabrication for generation of cell culture aggregates
US10092888B2 (en) 2014-11-07 2018-10-09 Genesis Technologies, Llc Linear reciprocating actuator
WO2016106192A2 (en) 2014-12-22 2016-06-30 Genzyme Corporation Methods of culturing a mammalian cell
WO2016128361A1 (en) * 2015-02-09 2016-08-18 Univercells Nv System, apparatus and method for the production of cells and/or cell products
US10358626B2 (en) 2016-04-12 2019-07-23 Artemis Biosystems, Inc. Perfusion filtration systems
EP3604547A1 (en) * 2016-04-14 2020-02-05 Trizell Ltd. Fixed-bed bioreactor with constant-flow pump/tubing system
FI3722435T3 (fi) 2016-04-14 2025-12-05 Ferring Ventures Ltd Kiinteäpetinen bioreaktori vakiovirtauspumppu/-putkijärjestelmällä
KR102414290B1 (ko) 2016-04-15 2022-06-29 베링거 인겔하임 인터내셔날 게엠베하 세포 보유 장치 및 방법
JPWO2018003476A1 (ja) * 2016-06-30 2019-01-17 富士フイルム株式会社 細胞懸濁液の膜分離方法及び細胞培養装置
WO2018011805A2 (en) * 2016-07-11 2018-01-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Systems and methods for growing cells in vitro
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
EP3652291B1 (en) 2017-07-14 2021-12-29 Corning Incorporated Cell culture vessel
JP7195302B2 (ja) 2017-07-14 2022-12-23 コーニング インコーポレイテッド ３ｄ培養のための細胞培養容器及び３ｄ細胞の培養方法
CN111051494B (zh) 2017-07-14 2024-03-29 康宁股份有限公司 用于手动或自动培养基交换的3d细胞培养容器
CN111051496B (zh) 2017-09-06 2024-03-08 富士胶片株式会社 产物的制造方法
EP3681989A1 (en) * 2017-09-15 2020-07-22 Bristol-Myers Squibb Company Online biomass capacitance monitoring during large scale production of polypeptides of interest
KR20250151558A (ko) 2017-10-06 2025-10-21 론자 리미티드 라만 분광법을 사용하는 세포 배양의 자동 제어
CN118580928A (zh) 2017-10-16 2024-09-03 里珍纳龙药品有限公司 灌注生物反应器及相关使用方法
TWI827570B (zh) * 2017-12-11 2024-01-01 美商安進公司 雙特異性抗體產品之連續製造製程
CA3088023C (en) * 2018-03-08 2023-03-21 Repligen Corporation Tangential flow depth filtration systems and methods of filtration using same
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
EP3770266A4 (en) * 2018-03-19 2021-06-09 FUJIFILM Corporation PRODUCT MANUFACTURING PROCESS
CN112165983A (zh) 2018-05-25 2021-01-01 瑞普利金公司 切向流过滤系统和方法
CN108504562A (zh) * 2018-06-21 2018-09-07 江苏澳创生物科技有限公司 一种发酵生产l-苏氨酸的系统及其应用
CN111065725B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 包括具有互联的壁的微板的流体装置
EP3649229B1 (en) 2018-07-13 2021-08-25 Corning Incorporated Cell culture vessels with stabilizer devices
WO2020013847A1 (en) 2018-07-13 2020-01-16 Corning Incorporated Microcavity dishes with sidewall including liquid medium delivery surface
US12478571B2 (en) 2018-12-17 2025-11-25 Pontis Biologics, Inc. Enzyme based compositions and methods for removing dental calculi
WO2020165873A1 (en) * 2019-02-15 2020-08-20 Oncosimis Biotech Private Limited Method and system for enhanced continuous production, secretion and separation of recombinant polypeptides from bacteria
WO2020223274A1 (en) * 2019-04-29 2020-11-05 Voyager Therapeutics, Inc. SYSTEMS AND METHODS FOR PRODUCING BACULOVIRAL INFECTED INSECT CELLS (BIICs) IN BIOREACTORS
CA3137494A1 (en) * 2019-06-13 2020-12-17 Amgen Inc. Automated biomass-based perfusion control in the manufacturing of biologics
JP7680418B2 (ja) * 2019-07-16 2025-05-20 イノベント バイオロジクス（スーチョウ）カンパニー，リミティド 高密度連続接種の細胞培養方法及びその応用
EP4058547A1 (en) * 2019-11-15 2022-09-21 Lonza Ltd. Process and system for producing an inoculum
CA3189533A1 (en) 2020-07-28 2022-02-03 Seagen Inc. Methods and systems for producing polypeptides
JP2024514327A (ja) * 2021-04-14 2024-04-01 ジェンザイム・コーポレーション 哺乳類細胞の灌流培養方法
EP4584299A2 (en) 2022-09-07 2025-07-16 Quantitative Biosciences, Inc. Fentanyl-specific single variable-domain antibodies and use in a continuous agglutination assay
CN116179464A (zh) * 2022-12-06 2023-05-30 无锡药明生物技术股份有限公司 提高培养液细胞密度和高密度细胞培养的方法
WO2024192171A1 (en) * 2023-03-14 2024-09-19 Sonnet BioTherapeutics, Inc. Methods of making recombinant il-12 albumin binding domain fusion proteins
WO2024192116A1 (en) * 2023-03-14 2024-09-19 Repligen Corporation High viable cell density transfection
WO2024226439A1 (en) 2023-04-24 2024-10-31 Quantitative Biosciences, Inc. Engineered biosensor strains of e. coli for continuous aerobic detection of analytes
WO2024248119A1 (ja) * 2023-05-31 2024-12-05 富士フイルム株式会社 生産物の生産方法
WO2025128343A1 (en) 2023-12-11 2025-06-19 Just-Evotec Biologics, Inc. Protein expression using trans-splicing and split selectable markers

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US54544A (en) * 1866-05-08 Improvement in low-water detecters
JPS61199788A (ja) 1985-02-28 1986-09-04 Mitsubishi Rayon Co Ltd 醗酵生成物の分離濃縮方法及び連続醗酵方法
US5286646A (en) 1985-11-25 1994-02-15 Boehringer Mannheim Gmbh Method for mammalian cell culture
GB8617646D0 (en) 1986-07-18 1986-08-28 Manchester Inst Science Tech Recovery of biological material
US4806484A (en) 1987-08-07 1989-02-21 Igb Products, Ltd. Perfusion airlift bioreactor
JPH0797982B2 (ja) 1987-09-24 1995-10-25 東洋紡績株式会社 細胞培養装置
US4921792A (en) 1987-11-27 1990-05-01 Miles Inc. Continuous cell dispersion, cultivation and substance recovery process
JPH01243985A (ja) 1988-03-25 1989-09-28 P C C Technol:Kk 植物器官の培養法及びその培養槽
US5595909A (en) * 1988-05-23 1997-01-21 Regents Of The University Of Minnesota Filter device
EP0343635B1 (en) 1988-05-25 1994-08-24 Teijin Limited Process for continuously culturing adherent animal cells
JPH02113896A (ja) * 1988-10-24 1990-04-26 Snow Brand Milk Prod Co Ltd ヒト抗リシンモノクローナル抗体およびそれを分泌するハイブリドーマ
US5019512A (en) * 1989-03-17 1991-05-28 Baxter International Inc. Spin filter for removing substantially cell-free culture medium from suspension cell culture system
JPH0541984A (ja) * 1990-09-07 1993-02-23 Dow Chem Co:The 攪拌容器における中空繊維においての細胞の増殖
US5256294A (en) 1990-09-17 1993-10-26 Genentech, Inc. Tangential flow filtration process and apparatus
GB9118664D0 (en) 1991-08-30 1991-10-16 Celltech Ltd Cell culture
JPH05153973A (ja) 1991-12-03 1993-06-22 Hitachi Ltd 細胞培養方法及び装置
US6204000B1 (en) 1995-04-28 2001-03-20 The United States Of America As Represented By The Department Of Health And Human Services Diagnostic methods and gene therapy using reagents derived from the human metastasis suppressor gene KAI1
JP2752918B2 (ja) * 1995-05-16 1998-05-18 ユーエイチティー株式会社 動物細胞のマイクロキャリア培養法
US6001585A (en) 1997-11-14 1999-12-14 Cellex Biosciences, Inc. Micro hollow fiber bioreactor
JP2997771B2 (ja) * 1998-06-29 2000-01-11 金沢大学長 細胞の懸濁培養方法
US6103526A (en) 1998-10-08 2000-08-15 Protein Sciences Corporation Spodoptera frugiperda single cell suspension cell line in serum-free media, methods of producing and using
US8026096B1 (en) 1998-10-08 2011-09-27 Protein Sciences Corporation In vivo active erythropoietin produced in insect cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
CA2252972C (en) 1998-11-26 2012-09-18 National Research Council Of Canada Serum-free production of recombinant proteins and adenoviral vectors
SI1147180T1 (sl) 1999-01-26 2009-06-30 Schering Plough Ltd Razmnoževnje govejega korona virusa v ovarijskih celicah kitajskega hrčka
US6855544B1 (en) * 1999-04-15 2005-02-15 Crucell Holland B.V. Recombinant protein production in a human cell
NZ514951A (en) 1999-04-15 2004-02-27 Crucell Holland B Recombinant protein production in a cultured human cell
JP2001149099A (ja) 1999-11-26 2001-06-05 Olympus Optical Co Ltd 染色体異常解析のための有核細胞の標本作製方法
EP1103610A1 (en) 1999-11-26 2001-05-30 Introgene B.V. Production of vaccines from immortalised mammalian cell lines
US6544424B1 (en) * 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
US6168941B1 (en) * 2000-04-07 2001-01-02 Genvec, Inc. Method of producing adenoviral vector stocks
JP4138209B2 (ja) 2000-06-29 2008-08-27 エーザイ・アール・アンド・ディー・マネジメント株式会社 プラバスタチン含有組成物
JP2002113896A (ja) 2000-10-05 2002-04-16 Seiko Epson Corp 画像形成装置
KR100882560B1 (ko) * 2001-04-17 2009-02-12 세이렌가부시끼가이샤 배지 첨가제 및 동물 세포 배양용 배지
DE10120835C2 (de) 2001-04-27 2003-04-10 Sifin Inst Fuer Immunpraeparat Verfahren zur Herstellung von monoklonalen Antikörpern
CA2351156A1 (en) 2001-07-04 2003-01-04 Peter W. Zandstra A bioprocess for the generation of pluripotent cell derived cells and tissues
ES2357423T3 (es) * 2001-08-31 2011-04-26 Bayer Schering Pharma Aktiengesellschaft Unidad y procedimiento para realizar fermentación a alta densidad celular.
ES2249616T3 (es) 2001-09-05 2006-04-01 Yamasa Corporation Citidina-fosfocolina para el tratamiento de la neuropatia diabetica.
WO2003025158A1 (en) 2001-09-14 2003-03-27 Medcell Biologics, Inc. Oxygen enriched bioreactor and method of culturing cells
JP2003219873A (ja) 2002-01-24 2003-08-05 Japan Science & Technology Corp サケ科キングサーモン由来の不死化細胞
US20030186335A1 (en) 2002-03-28 2003-10-02 National Institute Of Advanced Industrial Science And Technology Monoclonal antibodies, hybridomas, cell isolation method, isolated cells and immunological diagnostic method
DE10237082B4 (de) * 2002-08-09 2014-12-31 Sartorius Stedim Biotech Gmbh Verfahren und Vorrichtung zur biotechnologischen Herstellung von Wertstoffen
EP1623023B1 (en) 2003-05-09 2008-11-12 Crucell Holland B.V. Cultures of e1-immortalized cells and processes for culturing the same to increase product yields therefrom
JP2005041984A (ja) 2003-07-22 2005-02-17 Shin Kobe Electric Mach Co Ltd 水架橋ポリオレフィン製シートの製造法
ES2456015T3 (es) 2004-03-05 2014-04-21 Dsm Ip Assets B.V. Procedimiento para cultivar células mediante perfusión continua y flujo tangencial alternante
CN102876628A (zh) 2006-07-14 2013-01-16 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
JP2008308560A (ja) 2007-06-13 2008-12-25 Tohcello Co Ltd 表面防汚性複合フィルムの製造方法

Similar Documents

Publication Publication Date Title
JP2011125348A5 (enExample)
JP2016039817A5 (enExample)
JP2015507921A5 (enExample)
JP2012040033A5 (enExample)
JP2011525899A5 (enExample)
JP2012065652A5 (enExample)
JP2009511058A5 (enExample)
JP2016500260A5 (enExample)
NZ601424A (en) Method for the production of ad26 adenoviral vectors
JP2012507270A5 (enExample)
JP2013027385A5 (enExample)
JP2013517776A5 (enExample)
JP2016539627A5 (enExample)
JP2014208682A5 (enExample)
JP2011527428A5 (enExample)
JP2016539641A5 (enExample)
CN102858375A (zh) 载有干扰核糖核酸的细胞微粒子、其制备方法及其应用
WO2012166706A3 (en) Supramolecular nanofibers and hydrogels based on oligopeptides functionalized with nucleobases
JP2010500231A5 (enExample)
JP2012084502A5 (enExample)
JP2014513545A5 (enExample)
JP2016058130A5 (enExample)
TR201107238U (tr) Ticari araçların arka süspansiyonlarında uygulanan modüler yapı.
JP2010166901A5 (enExample)
JP2008280345A5 (enExample)