JP2011525899A5 - - Google Patents

Download PDF

Info

Publication number
JP2011525899A5
JP2011525899A5 JP2011515596A JP2011515596A JP2011525899A5 JP 2011525899 A5 JP2011525899 A5 JP 2011525899A5 JP 2011515596 A JP2011515596 A JP 2011515596A JP 2011515596 A JP2011515596 A JP 2011515596A JP 2011525899 A5 JP2011525899 A5 JP 2011525899A5
Authority
JP
Japan
Prior art keywords
satisfying
determining
following conditions
volume fraction
magnetic nanoparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2011515596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011525899A (ja
Filing date
Publication date
Priority claimed from GBGB0811856.4A external-priority patent/GB0811856D0/en
Application filed filed Critical
Publication of JP2011525899A publication Critical patent/JP2011525899A/ja
Publication of JP2011525899A5 publication Critical patent/JP2011525899A5/ja
Abandoned legal-status Critical Current

Links

JP2011515596A 2008-06-27 2009-06-26 磁性マイクロバブル、その作成方法及びその使用 Abandoned JP2011525899A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0811856.4 2008-06-27
GBGB0811856.4A GB0811856D0 (en) 2008-06-27 2008-06-27 Magnetic microbubbles, methods of preparing them and their uses
PCT/GB2009/001614 WO2009156743A2 (en) 2008-06-27 2009-06-26 Magnetic microbubbles, methods of preparing them and their uses

Publications (2)

Publication Number Publication Date
JP2011525899A JP2011525899A (ja) 2011-09-29
JP2011525899A5 true JP2011525899A5 (enExample) 2012-12-06

Family

ID=39683315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011515596A Abandoned JP2011525899A (ja) 2008-06-27 2009-06-26 磁性マイクロバブル、その作成方法及びその使用

Country Status (5)

Country Link
US (1) US9427396B2 (enExample)
EP (1) EP2296620B1 (enExample)
JP (1) JP2011525899A (enExample)
GB (1) GB0811856D0 (enExample)
WO (1) WO2009156743A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2600229T3 (es) * 2009-11-12 2017-02-07 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Nanopartículas magnéticas biocompatibles para el tratamiento de glioblastomas
TWI491425B (zh) * 2010-11-26 2015-07-11 Univ Chang Gung Targeting drug administration system and its operation method
KR101292939B1 (ko) 2010-12-31 2013-08-02 삼성전자주식회사 엠알유도 고강도집속초음파 치료 및 진단용 인지질 나노입자 및 이의 제조방법
DE102011000264B4 (de) 2011-01-21 2019-01-17 Surflay Nanotec Gmbh Mikrogasbläschen mit PVA-Wand, Herstellung und Verwendung von solchen Mikrogasbläschen
CZ304301B6 (cs) * 2012-09-19 2014-02-19 Vysoké Učení Technické V Brně Způsob přípravy magneticky vodivých prášků s využitím kavitace a zařízení k provádění tohoto způsobu
WO2016115133A1 (en) * 2015-01-12 2016-07-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Polymer microbubbles as x-ray dark field contrast agents
US10787670B2 (en) * 2016-09-15 2020-09-29 Labcyte Inc. High-efficiency transfection of biological cells using sonoporation
GB201716239D0 (en) * 2017-10-05 2017-11-22 Univ Oxford Innovation Ltd Compositions and methods for treating pseudoaneurysm
GB201716237D0 (en) * 2017-10-05 2017-11-22 Univ Oxford Innovation Ltd Magnetic-acoustic device
CN109946966B (zh) * 2019-03-15 2022-04-15 宁波大学 基于参数不确定量化的磁流体运动控制方法
US11883679B2 (en) * 2019-10-11 2024-01-30 North Carolina State University Systems and methods for ultrasound induced thrombolysis with magnetic microbubbles, optional nanodroplets, and a rotational magnetic field
GB201918428D0 (en) 2019-12-13 2020-01-29 Univ Oxford Innovation Ltd Functionalised microbubbles
DE102024207013B4 (de) * 2024-07-25 2026-02-19 Volkswagen Aktiengesellschaft Batterie und Verfahren zum Betrieb einer Batterie

Family Cites Families (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331654A (en) 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4652257A (en) * 1985-03-21 1987-03-24 The United States Of America As Represented By The Secretary Of The Navy Magnetically-localizable, polymerized lipid vesicles and method of disrupting same
DE3529195A1 (de) * 1985-08-14 1987-02-26 Max Planck Gesellschaft Kontrastmittel fuer ultraschalluntersuchungen und verfahren zu seiner herstellung
US4844882A (en) * 1987-12-29 1989-07-04 Molecular Biosystems, Inc. Concentrated stabilized microbubble-type ultrasonic imaging agent
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5228446A (en) 1989-12-22 1993-07-20 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5656211A (en) 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US5230882A (en) * 1989-12-22 1993-07-27 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
US5773024A (en) 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5123414A (en) * 1989-12-22 1992-06-23 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US20040208826A1 (en) 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) * 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) * 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
IN172208B (enExample) * 1990-04-02 1993-05-01 Sint Sa
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20080063603A1 (en) * 1990-04-02 2008-03-13 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5556610A (en) * 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US20030185759A1 (en) * 1990-05-18 2003-10-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5420176A (en) * 1990-06-01 1995-05-30 Imarx Pharmaceutical Corp. Contrast media for ultrasonic imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
EP0504340B1 (en) * 1990-10-05 1995-06-21 BRACCO International B.V. Method for the preparation of stable suspensions of hollow gas-filled microspheres suitable for ultrasonic echography
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
GB9106673D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
GB9106686D0 (en) 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) * 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5698397A (en) * 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US20050053552A1 (en) 1993-01-25 2005-03-10 Quay Steven C. Phase shift colloids as ultrasound contrast agents
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
EP0711179B2 (en) * 1993-07-30 2010-09-01 IMCOR Pharmaceutical Co. Stabilized microbubble compositions for ultrasound
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
DE4341478C2 (de) 1993-12-02 1998-10-08 Max Delbrueck Centrum Mittel zur Antitumortherapie
ATE234638T1 (de) 1993-12-15 2003-04-15 Bracco Research Sa Gas-mischungen verwendbar als ultraschallkontrastmittel
DE4412651A1 (de) 1994-04-13 1995-10-19 Mueller Schulte Detlef Dr Mittel zur selektiven AIDS Therapie sowie Verfahren zur Herstellung und Verwendung derselben
US5562893A (en) * 1994-08-02 1996-10-08 Molecular Biosystems, Inc. Gas-filled microspheres with fluorine-containing shells
US6132764A (en) 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
IL116328A (en) * 1994-12-16 1999-09-22 Bracco Research Sa Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging
GB2313310B (en) * 1995-01-19 1999-03-17 Cate Folkert Jan Ten Local delivery and monitoring of drugs
US6540981B2 (en) * 1997-12-04 2003-04-01 Amersham Health As Light imaging contrast agents
US5558092A (en) * 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US5997898A (en) * 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
AU707065B2 (en) 1995-08-29 1999-07-01 Nitto Denko Corporation Microporation of human skin for drug delivery and monitoring applications
US5876683A (en) * 1995-11-02 1999-03-02 Glumac; Nicholas Combustion flame synthesis of nanophase materials
JP4418033B2 (ja) * 1996-02-19 2010-02-17 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤のまたはそれに関する改良
US5976501A (en) * 1996-06-07 1999-11-02 Molecular Biosystems, Inc. Use of pressure resistant protein microspheres encapsulating gases as ultrasonic imaging agents for vascular perfusion
US20010051131A1 (en) * 1996-06-19 2001-12-13 Evan C. Unger Methods for delivering bioactive agents
ES2200187T3 (es) * 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
MXPA99001053A (es) * 1996-08-02 2002-03-11 Nycomed Imaging As Mejoramientos en o que se relacionan con agentes de contraste.
US6414139B1 (en) * 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
DE69738406T2 (de) * 1996-10-21 2008-12-04 Ge Healthcare As Verbesserungen in oder an Kontrastmitteln
WO1998018497A2 (en) * 1996-10-28 1998-05-07 Nycomed Imaging As Contrast agents
EP1001816A4 (en) 1996-11-25 2002-07-17 Imarx Pharmaceutical Corp PERFLUORINATED ETHER COMPOSITIONS FOR USE AS DIAGNOSTIC CONTRAST AGENTS
US6344272B1 (en) * 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
GB9708240D0 (en) * 1997-04-23 1997-06-11 Nycomed Imaging As Improvements in or relating to contrast agents
US20020159951A1 (en) * 1997-05-06 2002-10-31 Unger Evan C. Novel targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) * 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
AU7702798A (en) * 1997-05-30 1998-12-30 Alliance Pharmaceutical Corporation Methods and apparatus for monitoring and quantifying the movement of fluid
US20010053384A1 (en) * 1997-07-07 2001-12-20 James F. Greenleaf Site-directed transfection with ultrasound and cavitation nuclei
WO1999007415A1 (en) * 1997-08-12 1999-02-18 Bracco Research S.A. Administrable compositions and methods for magnetic resonance imaging
GB9717588D0 (en) * 1997-08-19 1997-10-22 Nycomed Imaging As Improvements in or relating to contrast agents
GB9717542D0 (en) * 1997-08-19 1997-10-22 Nycomed Imaging As Process
JP2001520207A (ja) 1997-10-21 2001-10-30 ニユコメド・イメージング・アクシエセルカペト 微小血管に標的設定された造影剤および血管拡張剤による超音波造影
US6896659B2 (en) * 1998-02-06 2005-05-24 Point Biomedical Corporation Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility
CA2327816A1 (en) 1998-04-09 1999-10-21 Nycomed Imaging As Use of particulate contrast agents in diagnostic imaging for studying physiological parameters
US20040170564A1 (en) 1998-04-22 2004-09-02 Roald Skurtveit Ultrasound contrast agent dispersions comprising gas and destabilising agent
DE69916822T2 (de) * 1998-04-28 2005-04-21 Amersham Health As Oslo Verbesserung von trennungsverfahren
US6548048B1 (en) * 1998-04-28 2003-04-15 Amersham Health As Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
GB9809776D0 (en) * 1998-05-07 1998-07-08 Nycomed Imaging As Method
WO1999059556A1 (en) 1998-05-15 1999-11-25 Nasa/Johnson Space Center Externally triggered microcapsules
GB2340225B (en) 1998-08-03 2002-11-13 Boris Zachar Gorbunov A detector and method for detecting ultra-low concentrations of molecules
AUPP899899A0 (en) * 1999-03-03 1999-03-25 Paragon Medical Limited Magnetic material
EP1176986B1 (en) * 1999-04-20 2018-07-04 Yale University Differentiation of monocytes into functional dendritic cells
JP3200704B2 (ja) 1999-05-13 2001-08-20 経済産業省産業技術総合研究所長 機能的に配置された磁気粒子・リポソーム粒子複合体
DE19924668A1 (de) * 1999-05-28 2000-11-30 Bayer Ag Substituierte alpha-Phenyl-beta-Ketosulfone
NZ533466A (en) 1999-06-28 2005-10-28 California Inst Of Techn Microfabricated elastomeric valve and pump systems
EP1202670A4 (en) 1999-08-13 2004-11-10 Point Biomedical Corp HOLLOW MICROSPHERES WITH CONTROLLED FRAGILITY FOR MEDICAL USE
EP1202671A4 (en) 1999-08-13 2004-11-10 Point Biomedical Corp MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
GB9920392D0 (en) * 1999-08-27 1999-11-03 Nycomed Imaging As Improvemets in or relating to diagnostic imaging
US6180087B1 (en) * 2000-01-18 2001-01-30 Mallinckrodt Inc. Tunable indocyanine dyes for biomedical applications
US6395257B1 (en) * 2000-01-18 2002-05-28 Mallinckrodt Inc. Dendrimer precursor dyes for imaging
AU2001258127B2 (en) * 2000-05-12 2005-11-10 Matregen Corp. Method of producing structures using centrifugal forces
US7109167B2 (en) * 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
DE10040380B4 (de) 2000-08-11 2006-03-09 Schering Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
US20030147812A1 (en) * 2001-12-11 2003-08-07 Friedrich Ueberle Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents
EP1474772A4 (en) 2002-02-14 2005-11-09 Immunivest Corp METHODS AND ALGORITHMS FOR COUNTING CELLS IN A SMALL CYTOMETER
US7105272B2 (en) 2002-02-15 2006-09-12 Nippon Soda Co., Ltd. Acid-degradable resin compositions containing ketene-aldehyde copolymer
US7211240B2 (en) * 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
EP1587944A4 (en) 2002-03-01 2007-03-21 Dyax Corp KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
WO2003081968A1 (en) * 2002-03-19 2003-10-02 California Institute Of Technology A method for integrating microparticles into mems
AUPS220302A0 (en) 2002-05-08 2002-06-06 Chang, Chak Man Thomas A plasma formed within bubbles in an aqueous medium and uses therefore
CA2418229A1 (en) * 2002-05-16 2003-11-16 Rohan Dharmakumar Microbubble construct for sensitivity enhanced mr manometry
CA2428896A1 (en) 2002-05-16 2003-11-16 Rohan Dharmakumar Microbubble construct for sensitivity enhanced mr manometry
US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
DE10224352A1 (de) 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
US20040086572A1 (en) 2002-07-17 2004-05-06 Dailey James P. Delivery of therapeutic agent affixed to magnetic particle
WO2004032970A2 (en) 2002-10-10 2004-04-22 Samir Mitragotri Carriers attached to blood cells
WO2004069284A2 (en) 2003-02-04 2004-08-19 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
WO2004071535A1 (en) 2003-02-13 2004-08-26 Bracco Imaging S.P.A. Contrast enhanced x-ray phase imaging
KR101025490B1 (ko) 2003-06-12 2011-04-04 브라코 인터내셔날 비.브이. 초음파 콘트라스트 조영에서 보충 커브 피팅을 통한 혈류 개산
US20060086834A1 (en) 2003-07-29 2006-04-27 Robert Pfeffer System and method for nanoparticle and nanoagglomerate fluidization
JP2007504944A (ja) 2003-09-10 2007-03-08 パランスキ ナフム ナノ粒子及びマイクロ粒子の製造方法
CN1215902C (zh) 2003-09-11 2005-08-24 复旦大学 一种具有核壳结构的磁性荧光双功能微球及其制备方法
WO2005025508A2 (en) 2003-09-12 2005-03-24 Bankruptcy Estate Of Ferx, Inc. Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
US20050074506A1 (en) 2003-10-02 2005-04-07 Brainsgate Ltd. Targeted release of nitric oxide in the CNS circulation for modulating the BBB and treating disorders
US20050089471A1 (en) 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089470A1 (en) 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US7329391B2 (en) 2003-12-08 2008-02-12 Applera Corporation Microfluidic device and material manipulating method using same
US20050175709A1 (en) * 2003-12-11 2005-08-11 Baty Ace M.Iii Therapeutic microparticles
EP1696965B1 (en) 2003-12-22 2014-12-10 Bracco Suisse SA Assembly of gas-filled microvesicle with active component for contrast imaging
JP4602993B2 (ja) 2004-01-16 2010-12-22 ボストン サイエンティフィック リミテッド 医用撮像のための方法及び装置
US20080193372A1 (en) 2004-02-10 2008-08-14 Barnes-Jewish Hospital Efficacy and Safety of Targeted Particulate Agents with Decoy Systems
WO2005079843A1 (ja) 2004-02-25 2005-09-01 Ttc Co., Ltd. 新規リポソーム
CN1667413A (zh) 2004-03-09 2005-09-14 中国科学院过程工程研究所 一种免疫磁性微球及其制备方法和用途
WO2005117999A2 (en) 2004-06-02 2005-12-15 Sidney Kimmel Cancer Center Imaging and therapeutic agents targeting proteins expressed on endothelial cell surface
DE102004036780A1 (de) 2004-07-29 2006-03-23 Dr. Kübler GmbH Verfahren zur In-vitro-Herstellung eines Stoffgemisches für ein tumorkrankes Individuum sowie Stoffgemisch für ein tumorkrankes Individuum
JP2006045132A (ja) 2004-08-05 2006-02-16 Konica Minolta Medical & Graphic Inc リポソーム含有磁気共鳴造影剤
CN101389273B (zh) 2004-08-05 2012-09-05 贝勒研究院 基因或药物递送系统
US7575738B2 (en) 2004-08-13 2009-08-18 General Electric Company Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US20060049116A1 (en) 2004-09-03 2006-03-09 Subramanian Krupakar M Method and apparatus for bubble glow discharge plasma treatment of fluids
EP1655040A1 (en) 2004-10-08 2006-05-10 Bracco Imaging, S.P.A. Contrast agent formulations for the visualization of the lymphatic system
EP1810688A1 (en) 2004-11-10 2007-07-25 Konica Minolta Medical & Graphic, Inc. Pharmaceutical preparation containing coated magnetic particles and method for production thereof, and diagnosis therapy system
US20090238767A1 (en) 2004-12-17 2009-09-24 Koninklijke Philips Electronics, N.V. Targeting contrast agents or targeting therapeutic agents for molecular imaging and therapy
JP2008524203A (ja) 2004-12-17 2008-07-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 分子イメージングのためのターゲティング剤
BRPI0519739A2 (pt) 2004-12-30 2009-03-10 Cinv Ag combinaÇço compreendendo um agente fornecendo um sinal, um material de implante e uma droga
AU2006209654A1 (en) 2005-01-28 2006-08-03 Konica Minolta Medical & Graphic, Inc. Pharmaceutical preparation containing magnetic vesicular particles, manufacturing method thereof and diagnostic therapeutic system
WO2006094951A1 (en) 2005-03-03 2006-09-14 Bracco Research Sa Medical imaging system based on a targeted contrast agent
CA2602946A1 (en) 2005-03-22 2006-09-28 Medstar Health, Inc. Delivery systems and methods for diagnosing and treating cardiovascular diseases
WO2006122414A1 (en) 2005-05-17 2006-11-23 Matregen Corp. Depot for sustained and controlled delivery of methotrexate
EP1909893A1 (de) 2005-07-28 2008-04-16 Pasquale Mosaico Herstellung von mitteln zur zustandsverbesserung von systemen und stoffen
WO2007015179A1 (en) 2005-08-03 2007-02-08 Koninklijke Philips Electronics, N.V. Ultrasound monitoring and feedback for magnetic hyperthermia
CN1315920C (zh) 2005-08-08 2007-05-16 北京师范大学 具有无机/有机核壳结构的磁性复合微球及其制备方法
GB0518273D0 (en) 2005-09-08 2005-10-19 Univ Dundee Apparatus and method for sonoporation
WO2007028981A1 (en) 2005-09-08 2007-03-15 University Of Dundee Apparatus and method for sonoporation
WO2007081410A2 (en) * 2005-09-13 2007-07-19 True Materials Incorporated Encoded microparticles
WO2007047149A2 (en) 2005-10-12 2007-04-26 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Susceptibility-matched multi-well sample holders for high-throughput screening by magnetic analysis
CN100560133C (zh) 2006-03-14 2009-11-18 中国人民解放军第二军医大学 磁性聚乳酸-羟基乙酸氧化酚砷纳米微球及其制药用途

Similar Documents

Publication Publication Date Title
JP2012502876A5 (enExample)
JP2011505522A5 (enExample)
JP2012021904A5 (enExample)
JP2008245635A5 (enExample)
JP2011526312A5 (enExample)
JP2010042027A5 (enExample)
JP2012507448A5 (enExample)
JP2010227108A5 (enExample)
JP2011508438A5 (enExample)
EP2822716A4 (en) IMPROVED ALUMINUM ALLOYS WITH MAGNESIUM, SILICON, MANGANE, IRON AND COPPER, AND METHOD FOR THE PRODUCTION THEREOF
JP2012020346A5 (enExample)
JP2012098988A5 (enExample)
JP2012511151A5 (enExample)
JP2014520090A5 (enExample)
JP2012518389A5 (enExample)
JP2012105193A5 (enExample)
JP2013505359A5 (enExample)
JP2012531301A5 (enExample)
JP2012515773A5 (enExample)
JP2013545093A5 (enExample)
FR2965190B1 (fr) Procede de fabrication de microcapsules polysiloxane fonctionnalisees et peu poreuses.
JP2011218309A5 (enExample)
JP2014513813A5 (enExample)
JP2013531183A5 (enExample)
JP2009523791A5 (enExample)