JP2011525899A5 - - Google Patents

Download PDF

Info

Publication number
JP2011525899A5
JP2011525899A5 JP2011515596A JP2011515596A JP2011525899A5 JP 2011525899 A5 JP2011525899 A5 JP 2011525899A5 JP 2011515596 A JP2011515596 A JP 2011515596A JP 2011515596 A JP2011515596 A JP 2011515596A JP 2011525899 A5 JP2011525899 A5 JP 2011525899A5
Authority
JP
Japan
Prior art keywords
satisfying
determining
following conditions
volume fraction
magnetic nanoparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2011515596A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011525899A (ja
Filing date
Publication date
Priority claimed from GBGB0811856.4A external-priority patent/GB0811856D0/en
Application filed filed Critical
Publication of JP2011525899A publication Critical patent/JP2011525899A/ja
Publication of JP2011525899A5 publication Critical patent/JP2011525899A5/ja
Abandoned legal-status Critical Current

Links

JP2011515596A 2008-06-27 2009-06-26 磁性マイクロバブル、その作成方法及びその使用 Abandoned JP2011525899A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0811856.4A GB0811856D0 (en) 2008-06-27 2008-06-27 Magnetic microbubbles, methods of preparing them and their uses
GB0811856.4 2008-06-27
PCT/GB2009/001614 WO2009156743A2 (en) 2008-06-27 2009-06-26 Magnetic microbubbles, methods of preparing them and their uses

Publications (2)

Publication Number Publication Date
JP2011525899A JP2011525899A (ja) 2011-09-29
JP2011525899A5 true JP2011525899A5 (enExample) 2012-12-06

Family

ID=39683315

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011515596A Abandoned JP2011525899A (ja) 2008-06-27 2009-06-26 磁性マイクロバブル、その作成方法及びその使用

Country Status (5)

Country Link
US (1) US9427396B2 (enExample)
EP (1) EP2296620B1 (enExample)
JP (1) JP2011525899A (enExample)
GB (1) GB0811856D0 (enExample)
WO (1) WO2009156743A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322142B1 (de) * 2009-11-12 2016-07-27 Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH Biokompatible, magnetische Nanopartikel zur Behandlung von Glioblastomen
TWI491425B (zh) * 2010-11-26 2015-07-11 Univ Chang Gung Targeting drug administration system and its operation method
KR101292939B1 (ko) 2010-12-31 2013-08-02 삼성전자주식회사 엠알유도 고강도집속초음파 치료 및 진단용 인지질 나노입자 및 이의 제조방법
DE102011000264B4 (de) 2011-01-21 2019-01-17 Surflay Nanotec Gmbh Mikrogasbläschen mit PVA-Wand, Herstellung und Verwendung von solchen Mikrogasbläschen
CZ304301B6 (cs) * 2012-09-19 2014-02-19 Vysoké Učení Technické V Brně Způsob přípravy magneticky vodivých prášků s využitím kavitace a zařízení k provádění tohoto způsobu
WO2016115133A1 (en) * 2015-01-12 2016-07-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Polymer microbubbles as x-ray dark field contrast agents
EP3512952B1 (en) * 2016-09-15 2024-05-15 Labcyte Inc. High-efficiency transfection of biological cells using sonoporation
GB201716237D0 (en) * 2017-10-05 2017-11-22 Univ Oxford Innovation Ltd Magnetic-acoustic device
GB201716239D0 (en) * 2017-10-05 2017-11-22 Univ Oxford Innovation Ltd Compositions and methods for treating pseudoaneurysm
CN109946966B (zh) * 2019-03-15 2022-04-15 宁波大学 基于参数不确定量化的磁流体运动控制方法
US11883679B2 (en) * 2019-10-11 2024-01-30 North Carolina State University Systems and methods for ultrasound induced thrombolysis with magnetic microbubbles, optional nanodroplets, and a rotational magnetic field
GB201918428D0 (en) 2019-12-13 2020-01-29 Univ Oxford Innovation Ltd Functionalised microbubbles

Family Cites Families (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331654A (en) 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
US4652257A (en) * 1985-03-21 1987-03-24 The United States Of America As Represented By The Secretary Of The Navy Magnetically-localizable, polymerized lipid vesicles and method of disrupting same
DE3529195A1 (de) * 1985-08-14 1987-02-26 Max Planck Gesellschaft Kontrastmittel fuer ultraschalluntersuchungen und verfahren zu seiner herstellung
US4844882A (en) * 1987-12-29 1989-07-04 Molecular Biosystems, Inc. Concentrated stabilized microbubble-type ultrasonic imaging agent
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5228446A (en) 1989-12-22 1993-07-20 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5230882A (en) * 1989-12-22 1993-07-27 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5773024A (en) 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5705187A (en) 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US5149319A (en) * 1990-09-11 1992-09-22 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids
US5123414A (en) * 1989-12-22 1992-06-23 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
US5656211A (en) 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US6613306B1 (en) * 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20040208826A1 (en) 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
IN172208B (enExample) * 1990-04-02 1993-05-01 Sint Sa
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US5578292A (en) * 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US6989141B2 (en) 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20080063603A1 (en) * 1990-04-02 2008-03-13 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5556610A (en) * 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20030185759A1 (en) * 1990-05-18 2003-10-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5420176A (en) * 1990-06-01 1995-05-30 Imarx Pharmaceutical Corp. Contrast media for ultrasonic imaging
US5215680A (en) * 1990-07-10 1993-06-01 Cavitation-Control Technology, Inc. Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles
US5310540A (en) * 1990-10-05 1994-05-10 Sintetica Sa Method for the preparation of stable suspensions of hollow gas-filled microspheres suitable for ultrasonic echography
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients
GB9106686D0 (en) 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
GB9106673D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5698397A (en) * 1995-06-07 1997-12-16 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
US20050053552A1 (en) 1993-01-25 2005-03-10 Quay Steven C. Phase shift colloids as ultrasound contrast agents
US5411730A (en) * 1993-07-20 1995-05-02 Research Corporation Technologies, Inc. Magnetic microparticles
JP3559849B2 (ja) * 1993-07-30 2004-09-02 アイエムシーオーアール ファーマシューティカル カンパニー 超音波技術のための安定化された微小気泡組成物
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
DE4341478C2 (de) 1993-12-02 1998-10-08 Max Delbrueck Centrum Mittel zur Antitumortherapie
DE69432295T2 (de) * 1993-12-15 2003-08-14 Bracco Research Sa Gas-mischungen verwendbar als ultraschallkontrastmittel
DE4412651A1 (de) 1994-04-13 1995-10-19 Mueller Schulte Detlef Dr Mittel zur selektiven AIDS Therapie sowie Verfahren zur Herstellung und Verwendung derselben
US5562893A (en) * 1994-08-02 1996-10-08 Molecular Biosystems, Inc. Gas-filled microspheres with fluorine-containing shells
US6132764A (en) 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
WO1998053855A1 (en) * 1997-05-30 1998-12-03 Alliance Pharmaceutical Corp. Methods and apparatus for monitoring and quantifying the movement of fluid
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
IL116328A (en) * 1994-12-16 1999-09-22 Bracco Research Sa Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging
WO1996022111A1 (en) * 1995-01-19 1996-07-25 Sound Science Limited Partnership Local delivery and monitoring of drugs
US6540981B2 (en) * 1997-12-04 2003-04-01 Amersham Health As Light imaging contrast agents
US5997898A (en) * 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US5558092A (en) * 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
CN1174713C (zh) 1995-08-29 2004-11-10 光谱股份有限公司 用于输药及检测的人体皮肤微穿孔设备
US5876683A (en) * 1995-11-02 1999-03-02 Glumac; Nicholas Combustion flame synthesis of nanophase materials
EA001135B1 (ru) * 1996-02-19 2000-10-30 Нюкомед Имагинг А/С Усовершенствования в области контрастных агентов
US5976501A (en) * 1996-06-07 1999-11-02 Molecular Biosystems, Inc. Use of pressure resistant protein microspheres encapsulating gases as ultrasonic imaging agents for vascular perfusion
US20010051131A1 (en) * 1996-06-19 2001-12-13 Evan C. Unger Methods for delivering bioactive agents
CA2259437C (en) * 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
ATE411055T1 (de) * 1996-08-02 2008-10-15 Ge Healthcare As Verbesserungen für oder in bezug auf kontrastmittel
US6414139B1 (en) * 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
US5846517A (en) * 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
ID21681A (id) * 1996-10-21 1999-07-08 Nycomed Imaging As Peningkatan pada atau berkenaan dengan zat-zat kontras
EP0946202B1 (en) * 1996-10-28 2003-09-10 Amersham Health AS Contrast agents
EP1001816A4 (en) 1996-11-25 2002-07-17 Imarx Pharmaceutical Corp PERFLUORINATED ETHER COMPOSITIONS FOR USE AS DIAGNOSTIC CONTRAST AGENTS
US6344272B1 (en) * 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
GB9708240D0 (en) * 1997-04-23 1997-06-11 Nycomed Imaging As Improvements in or relating to contrast agents
US20020159951A1 (en) * 1997-05-06 2002-10-31 Unger Evan C. Novel targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) * 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US20010053384A1 (en) * 1997-07-07 2001-12-20 James F. Greenleaf Site-directed transfection with ultrasound and cavitation nuclei
CN1103605C (zh) * 1997-08-12 2003-03-26 勃勒柯研究有限公司 磁共振成象用可投药组合物及方法
GB9717542D0 (en) * 1997-08-19 1997-10-22 Nycomed Imaging As Process
GB9717588D0 (en) * 1997-08-19 1997-10-22 Nycomed Imaging As Improvements in or relating to contrast agents
EP1024837A1 (en) 1997-10-21 2000-08-09 Nycomed Imaging As Ultrasound imaging with contrast agent targeted to microvasculature and a vasodilator drug
US6896659B2 (en) 1998-02-06 2005-05-24 Point Biomedical Corporation Method for ultrasound triggered drug delivery using hollow microbubbles with controlled fragility
AU760697B2 (en) 1998-04-09 2003-05-22 Ge Healthcare As Use of particulate contrast agents in diagnostic imaging for studying physiological parameters
US20040170564A1 (en) 1998-04-22 2004-09-02 Roald Skurtveit Ultrasound contrast agent dispersions comprising gas and destabilising agent
EP1073716B1 (en) * 1998-04-28 2004-04-28 Amersham Health AS Improvements in or relating to separation processes
US6548048B1 (en) * 1998-04-28 2003-04-15 Amersham Health As Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
GB9809776D0 (en) * 1998-05-07 1998-07-08 Nycomed Imaging As Method
DE69939258D1 (de) 1998-05-15 2008-09-18 Nasa Johnson Space Ct Mikrokapseln mit extern ausgelöster öffnung
GB2340225B (en) 1998-08-03 2002-11-13 Boris Zachar Gorbunov A detector and method for detecting ultra-low concentrations of molecules
AUPP899899A0 (en) * 1999-03-03 1999-03-25 Paragon Medical Limited Magnetic material
WO2000062818A1 (en) * 1999-04-20 2000-10-26 Richard Leslie Edelson Differentiation of monocytes into functional dendritic cells
JP3200704B2 (ja) 1999-05-13 2001-08-20 経済産業省産業技術総合研究所長 機能的に配置された磁気粒子・リポソーム粒子複合体
DE19924668A1 (de) * 1999-05-28 2000-11-30 Bayer Ag Substituierte alpha-Phenyl-beta-Ketosulfone
ATE215673T1 (de) 1999-06-28 2002-04-15 California Inst Of Techn Elastomerische mikropumpen- und mikroventilsysteme
EP1202670A4 (en) 1999-08-13 2004-11-10 Point Biomedical Corp HOLLOW MICROSPHERES WITH CONTROLLED FRAGILITY FOR MEDICAL USE
EP1202671A4 (en) 1999-08-13 2004-11-10 Point Biomedical Corp MICROPARTICLES USEFUL AS ULTRASONIC CONTRAST AGENTS FOR THE LYMPHATIC SYSTEM
GB9920392D0 (en) * 1999-08-27 1999-11-03 Nycomed Imaging As Improvemets in or relating to diagnostic imaging
US6395257B1 (en) * 2000-01-18 2002-05-28 Mallinckrodt Inc. Dendrimer precursor dyes for imaging
US6180087B1 (en) * 2000-01-18 2001-01-30 Mallinckrodt Inc. Tunable indocyanine dyes for biomedical applications
AU5812701A (en) * 2000-05-12 2001-11-20 Paul D Dalton Method of producing structures using centrifugal forces
CA2410887C (en) * 2000-06-02 2012-07-24 Bracco Research Usa Compounds for targeting endothelial cells, compositions containing the same and methods for their use
DE10040380B4 (de) 2000-08-11 2006-03-09 Schering Ag Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Plaques
EP1319423A3 (en) * 2001-12-11 2003-10-08 Dornier Medtech System GmbH Apparatus and method for initiating chemical reactions and for the targeted delivery of drugs or other agents
CA2759764C (en) 2002-02-14 2017-06-13 Veridex, Llc Methods and algorithms for cell enumeration in a low-cost cytometer
ATE463762T1 (de) 2002-02-15 2010-04-15 Nippon Soda Co Harz mit ketenaldehyd-copolymer
AU2003278807A1 (en) 2002-03-01 2004-08-13 Bracco International B.V. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US7211240B2 (en) * 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
WO2003081968A1 (en) * 2002-03-19 2003-10-02 California Institute Of Technology A method for integrating microparticles into mems
AUPS220302A0 (en) 2002-05-08 2002-06-06 Chang, Chak Man Thomas A plasma formed within bubbles in an aqueous medium and uses therefore
CA2418229A1 (en) * 2002-05-16 2003-11-16 Rohan Dharmakumar Microbubble construct for sensitivity enhanced mr manometry
CA2428896A1 (en) 2002-05-16 2003-11-16 Rohan Dharmakumar Microbubble construct for sensitivity enhanced mr manometry
US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
DE10224352A1 (de) 2002-06-01 2003-12-11 Mueller Schulte Detlef Thermosensitive Polymerträger mit veränderbarer physikalischer Struktur für die biochemische Analytik, Diagnostik und Therapie
WO2004006765A1 (en) 2002-07-17 2004-01-22 Dailey James P Delivery of therapeutic agent affixed to magnetic particle
AU2003300043A1 (en) 2002-10-10 2004-05-04 Elizabeth Chambers Carriers attached to blood cells
MXPA05007730A (es) 2003-02-04 2006-01-31 Bracco Int Bv Agentes de contraste para ultrasonido y proceso para la preparacion de los mismos.
WO2004071535A1 (en) 2003-02-13 2004-08-26 Bracco Imaging S.P.A. Contrast enhanced x-ray phase imaging
CA2526166C (en) 2003-06-12 2014-04-15 Bracco Research Sa Blood flow estimates through replenishment curve fitting in ultrasound contrast imaging
US20060086834A1 (en) 2003-07-29 2006-04-27 Robert Pfeffer System and method for nanoparticle and nanoagglomerate fluidization
US7883606B2 (en) 2003-09-10 2011-02-08 Nahum Parkansky Production of nanoparticles and microparticles
CN1215902C (zh) 2003-09-11 2005-08-24 复旦大学 一种具有核壳结构的磁性荧光双功能微球及其制备方法
US20060204442A1 (en) 2003-09-12 2006-09-14 Bankruptcy Estate Of Ferx, Inc. Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
US20050074506A1 (en) 2003-10-02 2005-04-07 Brainsgate Ltd. Targeted release of nitric oxide in the CNS circulation for modulating the BBB and treating disorders
US20050089470A1 (en) 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089471A1 (en) 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US7329391B2 (en) 2003-12-08 2008-02-12 Applera Corporation Microfluidic device and material manipulating method using same
US20050175709A1 (en) * 2003-12-11 2005-08-11 Baty Ace M.Iii Therapeutic microparticles
US20070081946A1 (en) 2003-12-22 2007-04-12 Bracco Research S.A. Assembly of gas-filled microvesicle with active component for contrast imaging
JP4602993B2 (ja) 2004-01-16 2010-12-22 ボストン サイエンティフィック リミテッド 医用撮像のための方法及び装置
EP1720521A4 (en) 2004-02-10 2008-11-05 Barnes Jewish Hospital IMPROVED EFFICIENCY AND SAFETY OF TARGETED MEANS WITH DECOY SYSTEMS
JPWO2005079843A1 (ja) 2004-02-25 2008-01-17 小林　猛 新規リポソーム
CN1667413A (zh) 2004-03-09 2005-09-14 中国科学院过程工程研究所 一种免疫磁性微球及其制备方法和用途
EP1755686A2 (en) 2004-06-02 2007-02-28 Sidney Kimmel Cancer Center Imaging and therapeutic agents targeting proteins expressed on endothelial cell surface
DE102004036780A1 (de) 2004-07-29 2006-03-23 Dr. Kübler GmbH Verfahren zur In-vitro-Herstellung eines Stoffgemisches für ein tumorkrankes Individuum sowie Stoffgemisch für ein tumorkrankes Individuum
JP2006045132A (ja) 2004-08-05 2006-02-16 Konica Minolta Medical & Graphic Inc リポソーム含有磁気共鳴造影剤
EP1793865A4 (en) 2004-08-05 2009-05-13 Baylor Res Inst GENETIC OR DRUG DELIVERY SYSTEM
US7575738B2 (en) 2004-08-13 2009-08-18 General Electric Company Heat shock protein as a targeting agent for endothelium-specific in vivo transduction
CN103120799A (zh) 2004-08-18 2013-05-29 博莱科瑞士股份有限公司 用于反差成像的充气微泡组合物
US20060049116A1 (en) 2004-09-03 2006-03-09 Subramanian Krupakar M Method and apparatus for bubble glow discharge plasma treatment of fluids
EP1655040A1 (en) 2004-10-08 2006-05-10 Bracco Imaging, S.P.A. Contrast agent formulations for the visualization of the lymphatic system
EP1810688A1 (en) 2004-11-10 2007-07-25 Konica Minolta Medical & Graphic, Inc. Pharmaceutical preparation containing coated magnetic particles and method for production thereof, and diagnosis therapy system
JP2008524203A (ja) 2004-12-17 2008-07-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 分子イメージングのためのターゲティング剤
CN101080240A (zh) 2004-12-17 2007-11-28 皇家飞利浦电子股份有限公司 用于分子成象和治疗的靶向造影剂或靶向治疗剂
WO2006069677A2 (en) 2004-12-30 2006-07-06 Cinvention Ag Combination comprising an agent providing a signal, an implant material and a drug
WO2006080243A1 (ja) 2005-01-28 2006-08-03 Konica Minolta Medical & Graphic, Inc. 被覆磁性粒子含有製剤およびその製造方法、並びに診断治療システム
US7846100B2 (en) 2005-03-03 2010-12-07 Bracco International Bv Medical imaging system based on a targeted contrast agent
WO2006102395A2 (en) 2005-03-22 2006-09-28 Medstar Health Inc Delivery systems and methods for diagnosing and treating cardiovascular diseases
WO2006122414A1 (en) 2005-05-17 2006-11-23 Matregen Corp. Depot for sustained and controlled delivery of methotrexate
RU2008107572A (ru) 2005-07-28 2009-09-10 Паскуале МОЗАИКО (CH) Способ получения средств для улучшения состояния систем и веществ, средство для улучшения состояния систем и применение этих средств для улучшения или оптимизации состояния систем и веществ
US20090312637A1 (en) 2005-08-03 2009-12-17 Koninklijke Philips Electronics, N.V. Ultrasound monitoring and feedback for magnetic hyperthermia
CN1315920C (zh) 2005-08-08 2007-05-16 北京师范大学 具有无机/有机核壳结构的磁性复合微球及其制备方法
GB0518273D0 (en) 2005-09-08 2005-10-19 Univ Dundee Apparatus and method for sonoporation
WO2007028981A1 (en) 2005-09-08 2007-03-15 University Of Dundee Apparatus and method for sonoporation
US8592136B2 (en) * 2005-09-13 2013-11-26 Affymetrix, Inc. Methods for producing codes for microparticles
WO2007047149A2 (en) 2005-10-12 2007-04-26 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Susceptibility-matched multi-well sample holders for high-throughput screening by magnetic analysis
CN100560133C (zh) 2006-03-14 2009-11-18 中国人民解放军第二军医大学 磁性聚乳酸-羟基乙酸氧化酚砷纳米微球及其制药用途

Similar Documents

Publication Publication Date Title
JP2011525899A5 (enExample)
JP2012502876A5 (enExample)
JP2011505522A5 (enExample)
JP2012021904A5 (enExample)
JP2010538767A5 (enExample)
JP2010042027A5 (enExample)
JP2012507448A5 (enExample)
JP2010227108A5 (enExample)
JP2013500200A5 (enExample)
JP2013546230A5 (enExample)
JP2011508438A5 (enExample)
EP2822716A4 (en) IMPROVED ALUMINUM ALLOYS WITH MAGNESIUM, SILICON, MANGANE, IRON AND COPPER, AND METHOD FOR THE PRODUCTION THEREOF
JP2011517729A5 (enExample)
JP2012531154A5 (enExample)
JP2012098988A5 (enExample)
JP2012020346A5 (enExample)
JP2014520090A5 (enExample)
JP2012518389A5 (enExample)
JP2012105193A5 (enExample)
JP2013505359A5 (enExample)
JP2011527428A5 (enExample)
JP2011500431A5 (enExample)
JP2012515773A5 (enExample)
JP2015520964A5 (enExample)
JP2013545093A5 (enExample)