PL1720972T3 - Proces hodowli komórek poprzez ciągłą perfuzję i zmienny przepływ styczny - Google Patents
Proces hodowli komórek poprzez ciągłą perfuzję i zmienny przepływ stycznyInfo
- Publication number
- PL1720972T3 PL1720972T3 PL05715787T PL05715787T PL1720972T3 PL 1720972 T3 PL1720972 T3 PL 1720972T3 PL 05715787 T PL05715787 T PL 05715787T PL 05715787 T PL05715787 T PL 05715787T PL 1720972 T3 PL1720972 T3 PL 1720972T3
- Authority
- PL
- Poland
- Prior art keywords
- tangential flow
- cell culturing
- continuous perfusion
- alternating tangential
- alternating
- Prior art date
Links
- 238000012258 culturing Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000010412 perfusion Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/06—Tissue, human, animal or plant cell, or virus culture apparatus with filtration, ultrafiltration, inverse osmosis or dialysis means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/10—Hollow fibers or tubes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Virology (AREA)
- Botany (AREA)
- Tropical Medicine & Parasitology (AREA)
- Water Supply & Treatment (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04075703 | 2004-03-05 | ||
| EP04075702 | 2004-03-05 | ||
| EP04077656 | 2004-09-27 | ||
| EP04077657 | 2004-09-27 | ||
| PCT/EP2005/002374 WO2005095578A1 (en) | 2004-03-05 | 2005-03-04 | Process for cell culturing by continuous perfusion and alternating tangential flow |
| EP05715787.7A EP1720972B1 (en) | 2004-03-05 | 2005-03-04 | Process for cell culturing by continuous perfusion and alternating tangential flow |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1720972T3 true PL1720972T3 (pl) | 2014-06-30 |
Family
ID=34961830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05715787T PL1720972T3 (pl) | 2004-03-05 | 2005-03-04 | Proces hodowli komórek poprzez ciągłą perfuzję i zmienny przepływ styczny |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US8206981B2 (enExample) |
| EP (3) | EP2308958A3 (enExample) |
| JP (6) | JP2007525984A (enExample) |
| KR (1) | KR101050585B1 (enExample) |
| CN (3) | CN104593277A (enExample) |
| AU (1) | AU2005229359C1 (enExample) |
| CA (1) | CA2557046A1 (enExample) |
| DK (1) | DK1720972T3 (enExample) |
| ES (1) | ES2456015T3 (enExample) |
| IL (2) | IL177724A (enExample) |
| PL (1) | PL1720972T3 (enExample) |
| PT (1) | PT1720972E (enExample) |
| SI (1) | SI1720972T1 (enExample) |
| WO (1) | WO2005095578A1 (enExample) |
Families Citing this family (86)
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|---|---|---|---|---|
| KR101050585B1 (ko) | 2004-03-05 | 2011-07-19 | 디에스엠 아이피 어셋츠 비.브이. | 연속식 살포 및 교호 접선 흐름에 의한 세포 배양 방법 |
| DK1988170T3 (da) | 2006-02-24 | 2019-07-22 | Toray Industries | Fremgangsmåde til fremstilling af et kemisk produkt og indretning til kontinuerlig fermentering |
| EP1870450A1 (en) * | 2006-06-21 | 2007-12-26 | DSMIP Assets B.V. | Process for the culturing of E1-immortalized HER cells |
| AU2011211462C1 (en) * | 2006-07-14 | 2015-01-22 | Dpx Holdings B.V. | Improved process for the culturing of cells |
| PT2634243T (pt) * | 2006-07-14 | 2017-12-18 | Patheon Holdings I B V | Método para melhorar a cultura de células |
| EP2014760A1 (en) | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
| DK2235197T3 (en) * | 2007-12-27 | 2017-10-09 | Baxalta GmbH | Methods of cell culture |
| WO2010003759A2 (en) * | 2008-06-17 | 2010-01-14 | Dsm Ip Assets B.V. | Cell culturing method |
| CN105708862B (zh) | 2008-09-02 | 2020-11-06 | 普拉里斯坦有限公司 | 来自胎盘组织的粘附细胞及其在治疗中的用途 |
| ES2532015T3 (es) * | 2008-11-03 | 2015-03-23 | Crucell Holland B.V. | Método para la producción de vectores adenovíricos |
| EP2454364B1 (en) | 2009-07-16 | 2014-04-23 | Crucell Holland B.V. | Production of polio virus at high titers for vaccine production |
| WO2011045378A1 (en) | 2009-10-15 | 2011-04-21 | Crucell Holland B.V. | Method for the purification of adenovirus particles |
| MX2012004221A (es) | 2009-10-15 | 2012-06-08 | Crucell Holland Bv | Proceso para purificacion de adenovirus de cultivos de alta densidad celular. |
| ES2642629T3 (es) | 2009-11-17 | 2017-11-17 | E. R. Squibb & Sons, L.L.C. | Métodos para la producción mejorada de proteínas |
| ES2578514T3 (es) * | 2010-02-15 | 2016-07-27 | Crucell Holland B.V. | Método para la producción de vectores adenovíricos |
| US20120315696A1 (en) * | 2010-02-15 | 2012-12-13 | Alfred Luitjens | METHOD FOR THE PRODUCTION OF Ad26 ADENOVIRAL VECTORS |
| WO2011144561A1 (en) | 2010-05-18 | 2011-11-24 | Crucell Holland B.V. | Methods for welding ethylene vinyl acetate (eva) tubing, tubing obtained thereby and use of such tubing for sterile transfer of content into a bioreactor |
| EP2625262B1 (en) * | 2010-10-05 | 2015-09-23 | Novo Nordisk Health Care AG | Process for protein production |
| BR112013028006A2 (pt) * | 2011-05-13 | 2016-09-06 | Octapharma Ag | método para aumentar a produtividade de células eucarióticas na produção do recombinante fviii |
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2005
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- 2005-03-04 ES ES05715787.7T patent/ES2456015T3/es not_active Expired - Lifetime
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- 2005-03-04 AU AU2005229359A patent/AU2005229359C1/en not_active Ceased
- 2005-03-04 US US10/591,118 patent/US8206981B2/en active Active
- 2005-03-04 EP EP10183651A patent/EP2308958A3/en not_active Withdrawn
- 2005-03-04 DK DK05715787.7T patent/DK1720972T3/da active
- 2005-03-04 CN CN201410471955.5A patent/CN104593277A/zh active Pending
- 2005-03-04 SI SI200531842T patent/SI1720972T1/sl unknown
- 2005-03-04 WO PCT/EP2005/002374 patent/WO2005095578A1/en not_active Ceased
- 2005-03-04 CA CA002557046A patent/CA2557046A1/en not_active Withdrawn
- 2005-03-04 EP EP05715787.7A patent/EP1720972B1/en not_active Revoked
- 2005-03-04 CN CN201410601800.9A patent/CN104388324A/zh active Pending
- 2005-03-04 JP JP2007501239A patent/JP2007525984A/ja active Pending
- 2005-03-04 PT PT57157877T patent/PT1720972E/pt unknown
- 2005-03-04 CN CNA2005800071754A patent/CN1930281A/zh active Pending
- 2005-03-04 EP EP12186351A patent/EP2540815A1/en not_active Ceased
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- 2012-05-23 US US13/478,307 patent/US20130266985A1/en not_active Abandoned
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