EP1789528A4 - Perfusion bioreactors for culturing cells - Google Patents

Perfusion bioreactors for culturing cells

Info

Publication number
EP1789528A4
EP1789528A4 EP05796533A EP05796533A EP1789528A4 EP 1789528 A4 EP1789528 A4 EP 1789528A4 EP 05796533 A EP05796533 A EP 05796533A EP 05796533 A EP05796533 A EP 05796533A EP 1789528 A4 EP1789528 A4 EP 1789528A4
Authority
EP
European Patent Office
Prior art keywords
culturing cells
perfusion bioreactors
bioreactors
perfusion
culturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05796533A
Other languages
German (de)
French (fr)
Other versions
EP1789528A2 (en
Inventor
Neil F Robbins
Jon Rowley
Mark Quinto
Abel Z Hastings
Bryan G Towns
Bradley R Snodgrass
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP1789528A2 publication Critical patent/EP1789528A2/en
Publication of EP1789528A4 publication Critical patent/EP1789528A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
EP05796533A 2004-09-16 2005-09-16 Perfusion bioreactors for culturing cells Withdrawn EP1789528A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94189204A 2004-09-16 2004-09-16
US69984905P 2005-07-18 2005-07-18
PCT/US2005/032818 WO2006033935A2 (en) 2004-09-16 2005-09-16 Perfusion bioreactor for culturing cells

Publications (2)

Publication Number Publication Date
EP1789528A2 EP1789528A2 (en) 2007-05-30
EP1789528A4 true EP1789528A4 (en) 2011-07-20

Family

ID=36090481

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05796533A Withdrawn EP1789528A4 (en) 2004-09-16 2005-09-16 Perfusion bioreactors for culturing cells

Country Status (5)

Country Link
EP (1) EP1789528A4 (en)
JP (1) JP4914835B2 (en)
AU (1) AU2005287162B2 (en)
CA (1) CA2579680A1 (en)
WO (1) WO2006033935A2 (en)

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US20100159590A1 (en) 2006-10-05 2010-06-24 Nanopoint, Inc. Systems and methods for active microfluidic cell handling
PT104155B (en) 2008-08-06 2017-04-05 Ass For The Advancement Of Tissue Eng And Cell Based Tech & Therapies (A4Tec) MULTI-CAMERA BIOREACTOR WITH BIDIRECTIONAL PERFUSION INTEGRATED IN A CULTURE SYSTEM FOR APPLICATION IN STRATEGIES OF TISSUE ENGINEERING
JP2010207174A (en) * 2009-03-12 2010-09-24 Atto Corp Perfusion cultivation system
CN102449135B (en) * 2009-03-26 2014-07-09 新加坡科技研究局 Apparatus for cell or tissue culture
JP4903252B2 (en) * 2009-11-30 2012-03-28 株式会社日立製作所 Cell culture equipment
JP5834020B2 (en) 2009-12-16 2015-12-16 ヴィヴァバイオセル・ソチエタ・ペル・アツィオーニ Continuous culture equipment
CA2791565C (en) * 2010-03-02 2018-08-28 Universite Technologie De Compiegne - Utc Multi-reactor unit for dynamic cell culture
US9453197B2 (en) 2010-12-16 2016-09-27 General Electric Company Methods of making cell carrier
US9534206B2 (en) 2010-12-16 2017-01-03 General Electric Company Cell carrier, associated methods for making cell carrier and culturing cells using the same
US9518249B2 (en) 2010-12-16 2016-12-13 General Electric Company Cell carrier, associated methods for making cell carrier and culturing cells using the same
US20120156777A1 (en) * 2010-12-16 2012-06-21 General Electric Company Cell carrier, associated methods for making cell carrier and culturing cells using the same
US9453196B2 (en) 2010-12-16 2016-09-27 General Electric Company Cell carrier, methods of making and use
US9926523B2 (en) 2010-12-16 2018-03-27 General Electric Company Cell carriers and methods for culturing cells
ES2529994T3 (en) * 2012-09-28 2015-02-25 Tissuse Gmbh Chip for multiple organs with improved life and homeostasis
GB201223495D0 (en) * 2012-12-30 2013-02-13 Plummer Simon M A Bioreactor
SG11201506339RA (en) 2013-02-22 2015-09-29 Genzyme Corp Microcarrier perfusion culturing methods and uses thereof
SG10201806083RA (en) 2013-02-22 2018-08-30 Genzyme Corp Microcarrier perfusion culturing methods and uses thereof
TWI743024B (en) * 2014-06-06 2021-10-21 美商健臻公司 Perfusion culturing methods and uses thereof
TWI776235B (en) 2014-06-09 2022-09-01 美商健臻公司 Seed train processes and uses thereof
IL308064A (en) 2014-12-22 2023-12-01 Genzyme Corp Methods of culturing a mammalian cell
US20180105784A1 (en) * 2015-03-30 2018-04-19 Takasago Electric, Inc. Culture medium exchange unit
JP6111510B1 (en) 2016-05-02 2017-04-12 インテグリカルチャー株式会社 Growth induction system, growth induction control device, growth induction control method, and growth induction control program
DE112016006830B4 (en) 2016-05-02 2024-02-22 Integriculture Inc. INTELLIGENT INDUCTION SYSTEM, AGING INDUCTION CONTROL DEVICE, AGING INDUCTION CONTROL METHOD AND AGING INDUCTION CONTROL PROGRAM
JP6968381B2 (en) * 2016-09-09 2021-11-17 国立大学法人 東京大学 Cell culture device
US11655439B2 (en) 2016-11-24 2023-05-23 AlveoliX Technologies AG Cell culturing system and method
CA3076212A1 (en) * 2017-09-19 2019-03-28 Advanced Solutions Life Sciences, Llc Well-plate and fluidic manifold assemblies and methods
CN107435023A (en) * 2017-09-19 2017-12-05 中国医学科学院输血研究所 A kind of bioreactor and biologic reaction equipment
CN112041422A (en) * 2018-02-08 2020-12-04 佛罗里达大学研究基金会公司 Bioreactor with perfusion function
US11680241B2 (en) 2018-02-08 2023-06-20 University Of Florida Research Foundation, Inc. Perfusion enabled bioreactors
JP7061356B2 (en) * 2018-02-28 2022-04-28 国立大学法人横浜国立大学 Culture equipment, methods for constructing two or more types of cell structures, and on-chip organ devices
WO2020179389A1 (en) * 2019-03-07 2020-09-10 Ｐｈｃホールディングス株式会社 Culture medium replacement device
EP4100509A1 (en) 2020-02-05 2022-12-14 LifeTaq-Analytics GmbH Three-dimensional cell culture
CN113025491A (en) * 2021-03-17 2021-06-25 杭州电子科技大学 Perfusion reactor for in-vitro dynamic culture of cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087292A2 (en) * 2002-04-08 2003-10-23 Millenium Biologix Inc. Automated tissue engineering system

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548263B1 (en) * 1997-05-29 2003-04-15 Cellomics, Inc. Miniaturized cell array methods and apparatus for cell-based screening
WO1999047922A2 (en) * 1998-03-18 1999-09-23 Massachusetts Institute Of Technology Vascularized perfused microtissue/micro-organ arrays
US20030215941A1 (en) * 2002-03-12 2003-11-20 Stewart Campbell Assay device that analyzes the absorption, metabolism, permeability and/or toxicity of a candidate compound

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003087292A2 (en) * 2002-04-08 2003-10-23 Millenium Biologix Inc. Automated tissue engineering system

Also Published As

Publication number Publication date
WO2006033935A2 (en) 2006-03-30
AU2005287162A1 (en) 2006-03-30
CA2579680A1 (en) 2006-03-30
AU2005287162B2 (en) 2010-12-23
JP4914835B2 (en) 2012-04-11
JP2008513013A (en) 2008-05-01
WO2006033935A9 (en) 2006-05-26
WO2006033935A3 (en) 2006-10-26
EP1789528A2 (en) 2007-05-30

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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17P Request for examination filed

Effective date: 20070302

AK Designated contracting states

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: ROBBINS, NEIL, F.

Inventor name: QUINTO, MARK

Inventor name: SNODGRASS, BRADLEY, R.

Inventor name: HASTINGS, ABEL, Z.

Inventor name: TOWNS, BRYAN, G.

Inventor name: ROWLEY, JON

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20110617

17Q First examination report despatched

Effective date: 20120306

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20120717