JP2013538588A5 - - Google Patents
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- Publication number
- JP2013538588A5 JP2013538588A5 JP2013532180A JP2013532180A JP2013538588A5 JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5 JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5
- Authority
- JP
- Japan
- Prior art keywords
- cell culture
- suspension
- hemostatic
- protein
- filter module
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10186545.9 | 2010-10-05 | ||
| EP10186545 | 2010-10-05 | ||
| US39271310P | 2010-10-13 | 2010-10-13 | |
| US61/392,713 | 2010-10-13 | ||
| PCT/EP2011/067372 WO2012045769A1 (en) | 2010-10-05 | 2011-10-05 | Process for protein production |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Division JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013538588A JP2013538588A (ja) | 2013-10-17 |
| JP2013538588A5 true JP2013538588A5 (enExample) | 2014-11-20 |
| JP6282467B2 JP6282467B2 (ja) | 2018-02-21 |
Family
ID=43735957
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532180A Active JP6282467B2 (ja) | 2010-10-05 | 2011-10-05 | タンパク質を生産するための方法 |
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10138290B2 (enExample) |
| EP (2) | EP2625262B1 (enExample) |
| JP (2) | JP6282467B2 (enExample) |
| CN (2) | CN107190034A (enExample) |
| ES (1) | ES2556454T3 (enExample) |
| PL (1) | PL2625262T3 (enExample) |
| WO (1) | WO2012045769A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015526094A (ja) * | 2012-08-20 | 2015-09-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞成長チャンバーを循環する流体の成分を濃縮する方法 |
| SG11201601182QA (en) | 2013-09-30 | 2016-04-28 | Crucell Holland Bv | Method for the clarification of high density crude cell culture harvest |
| JP6530171B2 (ja) * | 2014-09-09 | 2019-06-12 | 旭化成メディカル株式会社 | 培養産生物の回収方法 |
| CA3032099A1 (en) * | 2016-07-25 | 2018-02-01 | Repligen Corporation | Alternating tangential flow rapid harvesting |
| EP3700505A4 (en) * | 2017-10-26 | 2021-01-06 | Repligen Corporation | MICRO-ALTERNATIVE TANGENTIAL FLOW INFUSION FILTER, PROCESSING CONTAINER, AND METHODS OF USE THEREOF |
| TWI846694B (zh) | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| CN108504562A (zh) * | 2018-06-21 | 2018-09-07 | 江苏澳创生物科技有限公司 | 一种发酵生产l-苏氨酸的系统及其应用 |
| CA3144125A1 (en) * | 2019-07-16 | 2021-01-21 | Haihong Sun | Cell culture method based on high-density and continuous inoculation and use thereof |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1986006408A1 (en) | 1985-04-22 | 1986-11-06 | Genetics Institute, Inc. | HIGH YIElD PRODUCTION OF ACTIVE FACTOR IX |
| ATE87663T1 (de) | 1986-01-03 | 1993-04-15 | Genetics Inst | Verfahren zur herstellung von faktor-viii:c-typ- proteinen. |
| CA1331157C (en) | 1987-04-06 | 1994-08-02 | Randal J. Kaufman | Method for producing factor viii:c-type proteins |
| US4956080A (en) * | 1987-08-03 | 1990-09-11 | Microlift Systems, Incorporated | High pressure oxygen-saturated water treatment apparatus |
| JPH066054B2 (ja) | 1987-10-15 | 1994-01-26 | 帝人株式会社 | 動物細胞の培養方法 |
| JPH084495B2 (ja) | 1988-08-19 | 1996-01-24 | 帝人株式会社 | 接着性動物細胞の培養方法 |
| WO1990002175A1 (en) | 1988-08-16 | 1990-03-08 | Novo Nordisk A/S | A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors |
| US6268487B1 (en) * | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| US5851800A (en) | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
| AT409379B (de) * | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| DK1356073T3 (da) | 2000-10-20 | 2010-04-06 | Bioneer As | Fermenteringsfremgangsmåde til fremstilling af heterologe genprodukter i mælkesyrebakterier |
| US6960657B2 (en) | 2001-11-02 | 2005-11-01 | Novo Nordisk Healthcare A/G | Human coagulation factor VII polypeptides |
| JP2005512524A (ja) * | 2001-11-02 | 2005-05-12 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | ヒト凝固第ｖｉｉ因子ポリペプチド |
| ES2363205T3 (es) | 2002-06-21 | 2011-07-26 | Novo Nordisk Health Care Ag | Glicoformas del factor vii pegilado. |
| US7351688B2 (en) | 2003-02-05 | 2008-04-01 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein formulations |
| DE602004008451T2 (de) | 2003-05-01 | 2008-05-15 | Dsm Ip Assets B.V. | Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellen |
| NZ542585A (en) | 2003-05-09 | 2007-11-30 | Crucell Holland Bv | Cultures of PER.C6-immortalized cells and processes for culturing the same to increase product yields therefrom |
| ES2565077T3 (es) * | 2003-10-10 | 2016-03-31 | Novo Nordisk Health Care Ag | Método para producción en gran escala de un polipéptido en células eucariotas |
| PL1720972T3 (pl) | 2004-03-05 | 2014-06-30 | Dpx Holdings Bv | Proces hodowli komórek poprzez ciągłą perfuzję i zmienny przepływ styczny |
| RU2396347C2 (ru) | 2004-08-17 | 2010-08-10 | Ксл Бехринг Гмбх | Модифицированные витамин к-зависимые полипептиды |
| EP1707634A1 (en) | 2005-03-29 | 2006-10-04 | Octapharma AG | Method for isolation of recombinantly produced proteins |
| JP2009535019A (ja) | 2006-04-21 | 2009-10-01 | バイエル・ヘルスケア・エルエルシー | 灌流培養への哺乳動物細胞中の抗アポトーシス遺伝子の応用 |
| CN101490239A (zh) * | 2006-07-14 | 2009-07-22 | 帝斯曼知识产权资产管理有限公司 | 改进的细胞培养方法 |
| FI2343362T4 (fi) * | 2006-07-14 | 2024-07-04 | Patheon Holdings I B V | Parannettu menetelmä solujen viljelyä varten |
| EP1988101A1 (en) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Improvement of factor VIII polypeptide titers in cell cultures |
| EP2014760A1 (en) | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
| JP2009045019A (ja) | 2007-08-21 | 2009-03-05 | Toray Ind Inc | タンパク質の製造方法 |
| EP2268807A2 (en) * | 2008-04-21 | 2011-01-05 | Novo Nordisk A/S | Hyperglycosylated human coagulation factor ix |
| WO2010003759A2 (en) | 2008-06-17 | 2010-01-14 | Dsm Ip Assets B.V. | Cell culturing method |
-
2011
- 2011-10-05 WO PCT/EP2011/067372 patent/WO2012045769A1/en not_active Ceased
- 2011-10-05 CN CN201710499437.8A patent/CN107190034A/zh active Pending
- 2011-10-05 ES ES11764561.4T patent/ES2556454T3/es active Active
- 2011-10-05 EP EP11764561.4A patent/EP2625262B1/en not_active Revoked
- 2011-10-05 PL PL11764561T patent/PL2625262T3/pl unknown
- 2011-10-05 EP EP15174742.5A patent/EP2957628A1/en not_active Withdrawn
- 2011-10-05 CN CN2011800482244A patent/CN103154233A/zh active Pending
- 2011-10-05 US US13/823,847 patent/US10138290B2/en active Active
- 2011-10-05 JP JP2013532180A patent/JP6282467B2/ja active Active
-
2016
- 2016-08-04 JP JP2016153606A patent/JP2016187360A/ja not_active Withdrawn
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