JP2013538588A5 - - Google Patents
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- Publication number
- JP2013538588A5 JP2013538588A5 JP2013532180A JP2013532180A JP2013538588A5 JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5 JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013532180 A JP2013532180 A JP 2013532180A JP 2013538588 A5 JP2013538588 A5 JP 2013538588A5
- Authority
- JP
- Japan
- Prior art keywords
- cell culture
- suspension
- hemostatic
- protein
- filter module
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10186545 | 2010-10-05 | ||
| EP10186545.9 | 2010-10-05 | ||
| US39271310P | 2010-10-13 | 2010-10-13 | |
| US61/392,713 | 2010-10-13 | ||
| PCT/EP2011/067372 WO2012045769A1 (en) | 2010-10-05 | 2011-10-05 | Process for protein production |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Division JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013538588A JP2013538588A (ja) | 2013-10-17 |
| JP2013538588A5 true JP2013538588A5 (enExample) | 2014-11-20 |
| JP6282467B2 JP6282467B2 (ja) | 2018-02-21 |
Family
ID=43735957
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013532180A Active JP6282467B2 (ja) | 2010-10-05 | 2011-10-05 | タンパク質を生産するための方法 |
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016153606A Withdrawn JP2016187360A (ja) | 2010-10-05 | 2016-08-04 | タンパク質を生産するための方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10138290B2 (enExample) |
| EP (2) | EP2957628A1 (enExample) |
| JP (2) | JP6282467B2 (enExample) |
| CN (2) | CN107190034A (enExample) |
| ES (1) | ES2556454T3 (enExample) |
| PL (1) | PL2625262T3 (enExample) |
| WO (1) | WO2012045769A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104583386A (zh) * | 2012-08-20 | 2015-04-29 | 泰尔茂比司特公司 | 浓缩穿过细胞生长腔室循环的流体的组分 |
| BR112016006063A2 (pt) * | 2013-09-30 | 2017-08-01 | Crucell Holland Bv | método para clarificação de uma colheita de cultura celular em bruto |
| JP6530171B2 (ja) * | 2014-09-09 | 2019-06-12 | 旭化成メディカル株式会社 | 培養産生物の回収方法 |
| US11339775B2 (en) * | 2016-07-25 | 2022-05-24 | Repligen Corporation | Alternating tangential flow rapid harvesting |
| EP3700505A4 (en) | 2017-10-26 | 2021-01-06 | Repligen Corporation | MICRO-ALTERNATIVE TANGENTIAL FLOW INFUSION FILTER, PROCESSING CONTAINER, AND METHODS OF USE THEREOF |
| TWI846694B (zh) * | 2018-05-04 | 2024-07-01 | 美商健臻公司 | 具有過濾系統的灌注式生物反應器 |
| CN108504562A (zh) * | 2018-06-21 | 2018-09-07 | 江苏澳创生物科技有限公司 | 一种发酵生产l-苏氨酸的系统及其应用 |
| JP7680418B2 (ja) * | 2019-07-16 | 2025-05-20 | イノベント バイオロジクス（スーチョウ）カンパニー，リミティド | 高密度連続接種の細胞培養方法及びその応用 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4770999A (en) | 1985-04-22 | 1988-09-13 | Genetics Institute, Inc. | High yield production of active Factor IX |
| DE3785102T2 (de) | 1986-01-03 | 1993-07-22 | Genetics Inst | Verfahren zur herstellung von faktor-viii:c-typ-proteinen. |
| CA1331157C (en) | 1987-04-06 | 1994-08-02 | Randal J. Kaufman | Method for producing factor viii:c-type proteins |
| US4956080A (en) * | 1987-08-03 | 1990-09-11 | Microlift Systems, Incorporated | High pressure oxygen-saturated water treatment apparatus |
| JPH066054B2 (ja) | 1987-10-15 | 1994-01-26 | 帝人株式会社 | 動物細胞の培養方法 |
| JPH084495B2 (ja) | 1988-08-19 | 1996-01-24 | 帝人株式会社 | 接着性動物細胞の培養方法 |
| WO1990002175A1 (en) | 1988-08-16 | 1990-03-08 | Novo Nordisk A/S | A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors |
| US6268487B1 (en) | 1996-05-13 | 2001-07-31 | Genzyme Transgenics Corporation | Purification of biologically active peptides from milk |
| US5851800A (en) | 1996-05-14 | 1998-12-22 | Pharmacia & Upjohn Ab | Process for producing a protein |
| AT409379B (de) * | 1999-06-02 | 2002-07-25 | Baxter Ag | Medium zur protein- und serumfreien kultivierung von zellen |
| US6544424B1 (en) | 1999-12-03 | 2003-04-08 | Refined Technology Company | Fluid filtration system |
| PT1356073E (pt) | 2000-10-20 | 2010-02-15 | Bioneer As | Método de fermentação aperfeiçoado para a produção de produtos genéticos heterólogos em bactérias do ácido láctico |
| JP2005512524A (ja) | 2001-11-02 | 2005-05-12 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | ヒト凝固第ｖｉｉ因子ポリペプチド |
| US6960657B2 (en) | 2001-11-02 | 2005-11-01 | Novo Nordisk Healthcare A/G | Human coagulation factor VII polypeptides |
| UA86744C2 (en) | 2002-06-21 | 2009-05-25 | Ново Нордиск Хэлс Кеа Аг | Pegylated factor vii glycoforms |
| US7351688B2 (en) | 2003-02-05 | 2008-04-01 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein formulations |
| US20070065907A1 (en) | 2003-05-01 | 2007-03-22 | Dms Ip Assets B.V. | Process for the production of biological substances by perfusion culturing of suspended animal cells |
| WO2004099396A1 (en) | 2003-05-09 | 2004-11-18 | Crucell Holland B.V. | Cultures of e1-immortalized cells and processes for culturing the same to increase product yields therefrom |
| JP4740138B2 (ja) | 2003-10-10 | 2011-08-03 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 真核生物細胞におけるポリペプチドの大規模生産方法及びそれに適した培養容器 |
| CA2557046A1 (en) | 2004-03-05 | 2005-10-13 | John Crowley | Process for cell culturing by continuous perfusion and alternating tangential flow |
| WO2006018204A1 (en) | 2004-08-17 | 2006-02-23 | Zlb Behring Gmbh | Modified vitamin k dependent polypeptides |
| EP1707634A1 (en) | 2005-03-29 | 2006-10-04 | Octapharma AG | Method for isolation of recombinantly produced proteins |
| US20100167396A1 (en) | 2006-04-21 | 2010-07-01 | Bayer Healthcare Llc | Application of Anti-Apoptotic Gene Expression in Mammalian Cells for Perfusion Culture |
| KR101685246B1 (ko) * | 2006-07-14 | 2016-12-09 | 디피엑스 홀딩스 비.브이. | 개선된 세포 배양 방법 |
| CN101490239A (zh) * | 2006-07-14 | 2009-07-22 | 帝斯曼知识产权资产管理有限公司 | 改进的细胞培养方法 |
| EP1988101A1 (en) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Improvement of factor VIII polypeptide titers in cell cultures |
| EP2014760A1 (en) | 2007-06-13 | 2009-01-14 | CMC Biopharmaceuticals A/S | A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process |
| JP2009045019A (ja) | 2007-08-21 | 2009-03-05 | Toray Ind Inc | タンパク質の製造方法 |
| US20110137011A1 (en) | 2008-04-21 | 2011-06-09 | Novo Nordisk A/S | Hyperglycosylated human coagulation factor ix |
| WO2010003759A2 (en) | 2008-06-17 | 2010-01-14 | Dsm Ip Assets B.V. | Cell culturing method |
-
2011
- 2011-10-05 EP EP15174742.5A patent/EP2957628A1/en not_active Withdrawn
- 2011-10-05 CN CN201710499437.8A patent/CN107190034A/zh active Pending
- 2011-10-05 JP JP2013532180A patent/JP6282467B2/ja active Active
- 2011-10-05 WO PCT/EP2011/067372 patent/WO2012045769A1/en not_active Ceased
- 2011-10-05 CN CN2011800482244A patent/CN103154233A/zh active Pending
- 2011-10-05 EP EP11764561.4A patent/EP2625262B1/en not_active Revoked
- 2011-10-05 PL PL11764561T patent/PL2625262T3/pl unknown
- 2011-10-05 ES ES11764561.4T patent/ES2556454T3/es active Active
- 2011-10-05 US US13/823,847 patent/US10138290B2/en active Active
-
2016
- 2016-08-04 JP JP2016153606A patent/JP2016187360A/ja not_active Withdrawn
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