PL2625262T3 - Sposób wytwarzania białka - Google Patents

Sposób wytwarzania białka

Info

Publication number
PL2625262T3
PL2625262T3 PL11764561T PL11764561T PL2625262T3 PL 2625262 T3 PL2625262 T3 PL 2625262T3 PL 11764561 T PL11764561 T PL 11764561T PL 11764561 T PL11764561 T PL 11764561T PL 2625262 T3 PL2625262 T3 PL 2625262T3
Authority
PL
Poland
Prior art keywords
protein production
protein
production
Prior art date
Application number
PL11764561T
Other languages
English (en)
Polish (pl)
Inventor
Jarno Robin
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43735957&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2625262(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of PL2625262T3 publication Critical patent/PL2625262T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL11764561T 2010-10-05 2011-10-05 Sposób wytwarzania białka PL2625262T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP10186545 2010-10-05
US39271310P 2010-10-13 2010-10-13
PCT/EP2011/067372 WO2012045769A1 (en) 2010-10-05 2011-10-05 Process for protein production
EP11764561.4A EP2625262B1 (en) 2010-10-05 2011-10-05 Process for protein production

Publications (1)

Publication Number Publication Date
PL2625262T3 true PL2625262T3 (pl) 2016-05-31

Family

ID=43735957

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11764561T PL2625262T3 (pl) 2010-10-05 2011-10-05 Sposób wytwarzania białka

Country Status (7)

Country Link
US (1) US10138290B2 (enExample)
EP (2) EP2625262B1 (enExample)
JP (2) JP6282467B2 (enExample)
CN (2) CN103154233A (enExample)
ES (1) ES2556454T3 (enExample)
PL (1) PL2625262T3 (enExample)
WO (1) WO2012045769A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014031690A1 (en) * 2012-08-20 2014-02-27 Terumo Bct, Inc. Concentrating components of fluid circulated through a cell growth chamber
CN105579572B (zh) * 2013-09-30 2018-08-10 扬森疫苗与预防公司 用于净化高密度粗细胞培养收获物的方法
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
CN109689191B (zh) * 2016-07-25 2021-11-19 瑞普利金公司 交替切向流快速收获
WO2019084410A1 (en) * 2017-10-26 2019-05-02 Repligen Corporation MICRO-ALTERNATIVE TANGENTIALLY FLOWING INFUSION FILTER, TREATMENT CONTAINER, AND METHODS OF USING THE SAME
TWI846694B (zh) * 2018-05-04 2024-07-01 美商健臻公司 具有過濾系統的灌注式生物反應器
CN108504562A (zh) * 2018-06-21 2018-09-07 江苏澳创生物科技有限公司 一种发酵生产l-苏氨酸的系统及其应用
WO2021008571A1 (zh) * 2019-07-16 2021-01-21 信达生物制药(苏州)有限公司 高密度连续接种的细胞培养方法及其应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE74164T1 (de) 1985-04-22 1992-04-15 Genetics Inst Herstellung mit hoher leistung des aktivfaktors ix.
EP0253870B1 (en) 1986-01-03 1993-03-31 Genetics Institute, Inc. Method for producing factor viii:c-type proteins
CA1331157C (en) 1987-04-06 1994-08-02 Randal J. Kaufman Method for producing factor viii:c-type proteins
US4956080A (en) * 1987-08-03 1990-09-11 Microlift Systems, Incorporated High pressure oxygen-saturated water treatment apparatus
JPH066054B2 (ja) 1987-10-15 1994-01-26 帝人株式会社 動物細胞の培養方法
JPH084495B2 (ja) 1988-08-19 1996-01-24 帝人株式会社 接着性動物細胞の培養方法
WO1990002175A1 (en) 1988-08-16 1990-03-08 Novo Nordisk A/S A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors
US6268487B1 (en) 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
US5851800A (en) 1996-05-14 1998-12-22 Pharmacia & Upjohn Ab Process for producing a protein
AT409379B (de) * 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
US6544424B1 (en) * 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
PT1356073E (pt) 2000-10-20 2010-02-15 Bioneer As Método de fermentação aperfeiçoado para a produção de produtos genéticos heterólogos em bactérias do ácido láctico
US6960657B2 (en) 2001-11-02 2005-11-01 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
JP2005512524A (ja) 2001-11-02 2005-05-12 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト ヒト凝固第ｖｉｉ因子ポリペプチド
CN1671420A (zh) 2002-06-21 2005-09-21 诺和诺德医疗保健公司 Peg化因子ⅶ糖型
US7351688B2 (en) 2003-02-05 2008-04-01 The Research Foundation Of State University Of New York Compositions and methods for less immunogenic protein formulations
DK1620549T3 (da) 2003-05-01 2007-11-05 Dsm Ip Assets Bv Fremgangsmåde til fremstilling af biologiske stoffer ved perfusionsdyrkning af suspenderede dyreceller
ATE414144T1 (de) 2003-05-09 2008-11-15 Crucell Holland Bv Kulturen von e1-immortalisierten zellen und verfahren zu deren kultivierung zur erhöhung der produktausbeuten davon
EP1673452B1 (en) 2003-10-10 2015-12-23 Novo Nordisk Health Care AG Method for large-scale production of a polypeptide in eukaryote cells
CN104593277A (zh) * 2004-03-05 2015-05-06 帝斯曼知识产权资产管理有限公司 用于通过连续灌注和交互切向流来培养细胞的方法
JP2008509688A (ja) 2004-08-17 2008-04-03 ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー 改変ビタミンｋ依存性ポリペプチド
EP1707634A1 (en) 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
JP2009535019A (ja) 2006-04-21 2009-10-01 バイエル・ヘルスケア・エルエルシー 灌流培養への哺乳動物細胞中の抗アポトーシス遺伝子の応用
PT2634243T (pt) 2006-07-14 2017-12-18 Patheon Holdings I B V Método para melhorar a cultura de células
CN101490239A (zh) * 2006-07-14 2009-07-22 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
EP1988101A1 (en) 2007-05-04 2008-11-05 Novo Nordisk A/S Improvement of factor VIII polypeptide titers in cell cultures
EP2014760A1 (en) 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
JP2009045019A (ja) 2007-08-21 2009-03-05 Toray Ind Inc タンパク質の製造方法
EP2444491B1 (en) 2008-04-21 2016-11-16 Novo Nordisk Healthcare Ag Hyperglycosylated human coagulation factor IX
WO2010003759A2 (en) 2008-06-17 2010-01-14 Dsm Ip Assets B.V. Cell culturing method

Also Published As

Publication number Publication date
US20130244283A1 (en) 2013-09-19
CN107190034A (zh) 2017-09-22
JP2013538588A (ja) 2013-10-17
JP2016187360A (ja) 2016-11-04
EP2625262A1 (en) 2013-08-14
WO2012045769A1 (en) 2012-04-12
EP2625262B1 (en) 2015-09-23
US10138290B2 (en) 2018-11-27
JP6282467B2 (ja) 2018-02-21
ES2556454T3 (es) 2016-01-18
CN103154233A (zh) 2013-06-12
EP2957628A1 (en) 2015-12-23

Similar Documents

Publication Publication Date Title
PL2501822T3 (pl) Sposoby zwiększenia produkcji białek
GB201011502D0 (en) Novel process
HU1000010D0 (en) Novel process
GB201009673D0 (en) Novel process
GB201009676D0 (en) Novel process
HU1000386D0 (en) Novel process
GB201009671D0 (en) Novel process
ZA201207386B (en) Process for preparing benzoxaboroles
PL2625262T3 (pl) Sposób wytwarzania białka
EP2578725A4 (en) COATED ELEMENT AND METHOD FOR PRODUCING THE SAME
SG10201602874VA (en) Protein production method
PL2468877T3 (pl) Sposób wytwarzania enzymów
GB201004301D0 (en) Process
HUE044066T2 (hu) Eljárás metilén-difenil-diizocianát elõállítására
GB201115218D0 (en) Novel process
PT2571902T (pt) Novo processo.
GB201004299D0 (en) Process
EP2737065A4 (en) PROCESS FOR PRODUCING PROTEINS
IL223145A0 (en) Process for preparing dithiine-tetracarboxy-diimides
GB201008462D0 (en) Process
GB201101794D0 (en) Protein production
GB201009259D0 (en) Production process
PL393115A1 (pl) Sposób wytwarzania jogurtu
IL209321A0 (en) Process for manufacturing dibromonitromethane
GB201002974D0 (en) Novel process