PL2625262T3 - Sposób wytwarzania białka - Google Patents

Sposób wytwarzania białka

Info

Publication number
PL2625262T3
PL2625262T3 PL11764561T PL11764561T PL2625262T3 PL 2625262 T3 PL2625262 T3 PL 2625262T3 PL 11764561 T PL11764561 T PL 11764561T PL 11764561 T PL11764561 T PL 11764561T PL 2625262 T3 PL2625262 T3 PL 2625262T3
Authority
PL
Poland
Prior art keywords
protein production
protein
production
Prior art date
Application number
PL11764561T
Other languages
English (en)
Polish (pl)
Inventor
Jarno Robin
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43735957&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2625262(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Publication of PL2625262T3 publication Critical patent/PL2625262T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL11764561T 2010-10-05 2011-10-05 Sposób wytwarzania białka PL2625262T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP10186545 2010-10-05
US39271310P 2010-10-13 2010-10-13
PCT/EP2011/067372 WO2012045769A1 (en) 2010-10-05 2011-10-05 Process for protein production
EP11764561.4A EP2625262B1 (en) 2010-10-05 2011-10-05 Process for protein production

Publications (1)

Publication Number Publication Date
PL2625262T3 true PL2625262T3 (pl) 2016-05-31

Family

ID=43735957

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11764561T PL2625262T3 (pl) 2010-10-05 2011-10-05 Sposób wytwarzania białka

Country Status (7)

Country Link
US (1) US10138290B2 (enExample)
EP (2) EP2625262B1 (enExample)
JP (2) JP6282467B2 (enExample)
CN (2) CN107190034A (enExample)
ES (1) ES2556454T3 (enExample)
PL (1) PL2625262T3 (enExample)
WO (1) WO2012045769A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015526094A (ja) * 2012-08-20 2015-09-10 テルモ ビーシーティー、インコーポレーテッド 細胞成長チャンバーを循環する流体の成分を濃縮する方法
SG11201601182QA (en) 2013-09-30 2016-04-28 Crucell Holland Bv Method for the clarification of high density crude cell culture harvest
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
CA3032099A1 (en) * 2016-07-25 2018-02-01 Repligen Corporation Alternating tangential flow rapid harvesting
EP3700505A4 (en) * 2017-10-26 2021-01-06 Repligen Corporation MICRO-ALTERNATIVE TANGENTIAL FLOW INFUSION FILTER, PROCESSING CONTAINER, AND METHODS OF USE THEREOF
TWI846694B (zh) 2018-05-04 2024-07-01 美商健臻公司 具有過濾系統的灌注式生物反應器
CN108504562A (zh) * 2018-06-21 2018-09-07 江苏澳创生物科技有限公司 一种发酵生产l-苏氨酸的系统及其应用
CA3144125A1 (en) * 2019-07-16 2021-01-21 Haihong Sun Cell culture method based on high-density and continuous inoculation and use thereof

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006408A1 (en) 1985-04-22 1986-11-06 Genetics Institute, Inc. HIGH YIElD PRODUCTION OF ACTIVE FACTOR IX
ATE87663T1 (de) 1986-01-03 1993-04-15 Genetics Inst Verfahren zur herstellung von faktor-viii:c-typ- proteinen.
CA1331157C (en) 1987-04-06 1994-08-02 Randal J. Kaufman Method for producing factor viii:c-type proteins
US4956080A (en) * 1987-08-03 1990-09-11 Microlift Systems, Incorporated High pressure oxygen-saturated water treatment apparatus
JPH066054B2 (ja) 1987-10-15 1994-01-26 帝人株式会社 動物細胞の培養方法
JPH084495B2 (ja) 1988-08-19 1996-01-24 帝人株式会社 接着性動物細胞の培養方法
WO1990002175A1 (en) 1988-08-16 1990-03-08 Novo Nordisk A/S A method of producing polypeptides by culturing eukaryotic cells in the presence of protease inhibitors
US6268487B1 (en) * 1996-05-13 2001-07-31 Genzyme Transgenics Corporation Purification of biologically active peptides from milk
US5851800A (en) 1996-05-14 1998-12-22 Pharmacia & Upjohn Ab Process for producing a protein
AT409379B (de) * 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
US6544424B1 (en) 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
DK1356073T3 (da) 2000-10-20 2010-04-06 Bioneer As Fermenteringsfremgangsmåde til fremstilling af heterologe genprodukter i mælkesyrebakterier
US6960657B2 (en) 2001-11-02 2005-11-01 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
JP2005512524A (ja) * 2001-11-02 2005-05-12 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト ヒト凝固第ｖｉｉ因子ポリペプチド
ES2363205T3 (es) 2002-06-21 2011-07-26 Novo Nordisk Health Care Ag Glicoformas del factor vii pegilado.
US7351688B2 (en) 2003-02-05 2008-04-01 The Research Foundation Of State University Of New York Compositions and methods for less immunogenic protein formulations
DE602004008451T2 (de) 2003-05-01 2008-05-15 Dsm Ip Assets B.V. Verfahren zur herstellung von biologischen substanzen durch perfusionskultivierung von suspendierten tierischen zellen
NZ542585A (en) 2003-05-09 2007-11-30 Crucell Holland Bv Cultures of PER.C6-immortalized cells and processes for culturing the same to increase product yields therefrom
ES2565077T3 (es) * 2003-10-10 2016-03-31 Novo Nordisk Health Care Ag Método para producción en gran escala de un polipéptido en células eucariotas
PL1720972T3 (pl) 2004-03-05 2014-06-30 Dpx Holdings Bv Proces hodowli komórek poprzez ciągłą perfuzję i zmienny przepływ styczny
RU2396347C2 (ru) 2004-08-17 2010-08-10 Ксл Бехринг Гмбх Модифицированные витамин к-зависимые полипептиды
EP1707634A1 (en) 2005-03-29 2006-10-04 Octapharma AG Method for isolation of recombinantly produced proteins
JP2009535019A (ja) 2006-04-21 2009-10-01 バイエル・ヘルスケア・エルエルシー 灌流培養への哺乳動物細胞中の抗アポトーシス遺伝子の応用
CN101490239A (zh) * 2006-07-14 2009-07-22 帝斯曼知识产权资产管理有限公司 改进的细胞培养方法
FI2343362T4 (fi) * 2006-07-14 2024-07-04 Patheon Holdings I B V Parannettu menetelmä solujen viljelyä varten
EP1988101A1 (en) 2007-05-04 2008-11-05 Novo Nordisk A/S Improvement of factor VIII polypeptide titers in cell cultures
EP2014760A1 (en) 2007-06-13 2009-01-14 CMC Biopharmaceuticals A/S A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
JP2009045019A (ja) 2007-08-21 2009-03-05 Toray Ind Inc タンパク質の製造方法
EP2268807A2 (en) * 2008-04-21 2011-01-05 Novo Nordisk A/S Hyperglycosylated human coagulation factor ix
WO2010003759A2 (en) 2008-06-17 2010-01-14 Dsm Ip Assets B.V. Cell culturing method

Also Published As

Publication number Publication date
JP2013538588A (ja) 2013-10-17
JP6282467B2 (ja) 2018-02-21
EP2957628A1 (en) 2015-12-23
EP2625262A1 (en) 2013-08-14
EP2625262B1 (en) 2015-09-23
ES2556454T3 (es) 2016-01-18
JP2016187360A (ja) 2016-11-04
US20130244283A1 (en) 2013-09-19
US10138290B2 (en) 2018-11-27
CN103154233A (zh) 2013-06-12
WO2012045769A1 (en) 2012-04-12
CN107190034A (zh) 2017-09-22

Similar Documents

Publication Publication Date Title
PT2501822T (pt) Métodos para produção de proteínas melhorada
GB201011502D0 (en) Novel process
GB201103499D0 (en) Process
HU1000010D0 (en) Novel process
GB201011446D0 (en) Process
GB201009676D0 (en) Novel process
GB201009673D0 (en) Novel process
HU1000386D0 (en) Novel process
GB201011444D0 (en) Process
GB201009671D0 (en) Novel process
ZA201207386B (en) Process for preparing benzoxaboroles
SG10201602874VA (en) Protein production method
EP2578725A4 (en) COATED ELEMENT AND METHOD FOR PRODUCING THE SAME
GB201012418D0 (en) Process
GB201004301D0 (en) Process
HUE044066T2 (hu) Eljárás metilén-difenil-diizocianát elõállítására
PL2468877T3 (pl) Sposób wytwarzania enzymów
GB201011063D0 (en) Process
GB201115218D0 (en) Novel process
GB201009172D0 (en) Process
PT2571902T (pt) Novo processo.
GB201004299D0 (en) Process
EP2737065A4 (en) PROCESS FOR PRODUCING PROTEINS
IL223145A0 (en) Process for preparing dithiine-tetracarboxy-diimides
GB201101794D0 (en) Protein production