JP2015532096A5 - - Google Patents
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- JP2015532096A5 JP2015532096A5 JP2015534771A JP2015534771A JP2015532096A5 JP 2015532096 A5 JP2015532096 A5 JP 2015532096A5 JP 2015534771 A JP2015534771 A JP 2015534771A JP 2015534771 A JP2015534771 A JP 2015534771A JP 2015532096 A5 JP2015532096 A5 JP 2015532096A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- acid sequence
- aoi
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261708554P | 2012-10-01 | 2012-10-01 | |
| US61/708,554 | 2012-10-01 | ||
| PCT/US2013/062410 WO2014055370A1 (en) | 2012-10-01 | 2013-09-27 | Compostions and methods for producing glycoproteins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015532096A JP2015532096A (ja) | 2015-11-09 |
| JP2015532096A5 true JP2015532096A5 (enExample) | 2016-11-17 |
| JP6351598B2 JP6351598B2 (ja) | 2018-07-04 |
Family
ID=49354940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015534771A Active JP6351598B2 (ja) | 2012-10-01 | 2013-09-27 | 糖タンパク質を産生するための組成物および方法 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20150259425A1 (enExample) |
| EP (1) | EP2904092B1 (enExample) |
| JP (1) | JP6351598B2 (enExample) |
| KR (1) | KR102182885B1 (enExample) |
| CN (1) | CN104797707A (enExample) |
| AU (1) | AU2013327681B2 (enExample) |
| BR (1) | BR112015007319B1 (enExample) |
| CA (1) | CA2886753C (enExample) |
| CY (1) | CY1119602T1 (enExample) |
| DK (1) | DK2904092T3 (enExample) |
| EA (1) | EA201590550A1 (enExample) |
| ES (1) | ES2646594T3 (enExample) |
| HK (1) | HK1207394A1 (enExample) |
| HR (1) | HRP20171753T1 (enExample) |
| HU (1) | HUE034896T2 (enExample) |
| IL (1) | IL237916A0 (enExample) |
| IN (1) | IN2015DN02630A (enExample) |
| LT (1) | LT2904092T (enExample) |
| ME (1) | ME02882B (enExample) |
| MX (1) | MX366106B (enExample) |
| NO (1) | NO2760138T3 (enExample) |
| PL (1) | PL2904092T3 (enExample) |
| PT (1) | PT2904092T (enExample) |
| RS (1) | RS56641B1 (enExample) |
| SG (2) | SG11201502339YA (enExample) |
| SI (1) | SI2904092T1 (enExample) |
| SM (1) | SMT201700588T1 (enExample) |
| WO (1) | WO2014055370A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014018747A2 (en) | 2012-07-26 | 2014-01-30 | Momenta Pharmaceuticals, Inc. | Glycoproteins with anti-inflammatory properties |
| AU2014337263B2 (en) | 2013-10-16 | 2019-12-12 | Outlook Therapeutics, Inc. | Buffer formulations for enhanced antibody stability |
| CA2966005C (en) | 2014-10-31 | 2021-04-27 | Abbvie Biotherapeutics Inc. | Anti-cs1 antibodies and antibody drug conjugates |
| EP3247718B1 (en) | 2015-01-21 | 2021-09-01 | Outlook Therapeutics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
| AU2017206012A1 (en) * | 2016-01-06 | 2018-07-26 | Outlook Therapeutics, Inc. | Reduction of high molecular weight species, acidic charge species, and fragments in a monoclonal antibody composition |
| JP6674028B2 (ja) * | 2016-01-06 | 2020-04-01 | アウトルック セラピューティクス，インコーポレイティド | モノクローナル抗体組成物中のアフコシル化種の調節 |
| EP3411401A1 (en) | 2016-02-03 | 2018-12-12 | Oncobiologics, Inc. | Buffer formulations for enhanced antibody stability |
| EP3420072B1 (en) | 2016-02-22 | 2025-06-18 | Agency for Science, Technology and Research | Cell culture medium |
| WO2018089928A1 (en) * | 2016-11-11 | 2018-05-17 | Whitehead Institute For Biomedical Research | Human plasma-like medium |
| US12325737B2 (en) | 2018-03-26 | 2025-06-10 | Amgen Inc. | Total afucosylated glycoforms of antibodies produced in cell culture |
| CA3103610A1 (en) | 2018-06-12 | 2019-12-19 | The Regents Of The University Of California | Single-chain bispecific chimeric antigen receptors for the treatment of cancer |
| KR20220002963A (ko) * | 2019-04-18 | 2022-01-07 | 얀센 바이오테크 인코포레이티드 | 시알릴화된 당단백질 |
| CN111944050B (zh) * | 2020-08-19 | 2022-05-13 | 苏州普乐康医药科技有限公司 | 一种抗b7-h3抗体及其应用 |
| CN113337562B (zh) * | 2021-05-24 | 2022-06-03 | 宁波人健药业集团股份有限公司 | 使用CHO细胞高效发酵生产rhCG的方法 |
| CN113480632B (zh) * | 2021-07-30 | 2023-02-03 | 宁波人健药业集团股份有限公司 | 一种在CHO细胞中表达的重组蛋白rhCG纯化工艺 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
| US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
| US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| EP1690935A3 (en) | 1990-01-12 | 2008-07-30 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| IE922437A1 (en) | 1991-07-25 | 1993-01-27 | Idec Pharma Corp | Recombinant antibodies for human therapy |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| PT1024191E (pt) | 1991-12-02 | 2008-12-22 | Medical Res Council | Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| CA2219361C (en) | 1995-04-27 | 2012-02-28 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| WO1996034096A1 (en) | 1995-04-28 | 1996-10-31 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US5705364A (en) | 1995-06-06 | 1998-01-06 | Genentech, Inc. | Mammalian cell culture process |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| EP1972194A1 (en) | 1996-12-03 | 2008-09-24 | Amgen Fremont Inc. | Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom |
| JP3876002B2 (ja) | 1997-04-14 | 2007-01-31 | ミクロメート・アクチエンゲゼルシャフト | 抗ヒト抗原受容体を産生するための斬新な方法およびそれらの使用 |
| US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
| DE60230858D1 (de) * | 2001-02-15 | 2009-03-05 | Centocor Inc | Chemisch definiertes medium für kultivierte säugerzellen |
| US7709610B2 (en) | 2003-05-08 | 2010-05-04 | Facet Biotech Corporation | Therapeutic use of anti-CS1 antibodies |
| ATE531388T1 (de) | 2004-03-24 | 2011-11-15 | Abbott Biotherapeutics Corp | Verwendung von anti-alpha5beta1-antikörpern zur hemmung der krebszellproliferation |
| AU2005335714B2 (en) | 2004-11-10 | 2012-07-26 | Macrogenics, Inc. | Engineering Fc antibody regions to confer effector function |
| EP2545938A1 (en) | 2007-08-03 | 2013-01-16 | Abbott Biotherapeutics Corp. | Therapeutic use of anti-tweak receptor antibodies |
-
2012
- 2012-01-12 NO NO14160512A patent/NO2760138T3/no unknown
-
2013
- 2013-09-27 SG SG11201502339YA patent/SG11201502339YA/en unknown
- 2013-09-27 DK DK13776656.4T patent/DK2904092T3/en active
- 2013-09-27 IN IN2630DEN2015 patent/IN2015DN02630A/en unknown
- 2013-09-27 SM SM20170588T patent/SMT201700588T1/it unknown
- 2013-09-27 MX MX2015004027A patent/MX366106B/es active IP Right Grant
- 2013-09-27 JP JP2015534771A patent/JP6351598B2/ja active Active
- 2013-09-27 SI SI201330877T patent/SI2904092T1/en unknown
- 2013-09-27 WO PCT/US2013/062410 patent/WO2014055370A1/en not_active Ceased
- 2013-09-27 ME MEP-2017-285A patent/ME02882B/me unknown
- 2013-09-27 AU AU2013327681A patent/AU2013327681B2/en active Active
- 2013-09-27 RS RS20171200A patent/RS56641B1/sr unknown
- 2013-09-27 SG SG10201702448WA patent/SG10201702448WA/en unknown
- 2013-09-27 HR HRP20171753TT patent/HRP20171753T1/hr unknown
- 2013-09-27 LT LTEP13776656.4T patent/LT2904092T/lt unknown
- 2013-09-27 HK HK15108000.4A patent/HK1207394A1/xx unknown
- 2013-09-27 EA EA201590550A patent/EA201590550A1/ru unknown
- 2013-09-27 ES ES13776656.4T patent/ES2646594T3/es active Active
- 2013-09-27 CN CN201380058690.XA patent/CN104797707A/zh active Pending
- 2013-09-27 BR BR112015007319-0A patent/BR112015007319B1/pt active IP Right Grant
- 2013-09-27 EP EP13776656.4A patent/EP2904092B1/en active Active
- 2013-09-27 CA CA2886753A patent/CA2886753C/en active Active
- 2013-09-27 US US14/432,653 patent/US20150259425A1/en not_active Abandoned
- 2013-09-27 PL PL13776656T patent/PL2904092T3/pl unknown
- 2013-09-27 KR KR1020157009991A patent/KR102182885B1/ko active Active
- 2013-09-27 HU HUE13776656A patent/HUE034896T2/hu unknown
- 2013-09-27 PT PT137766564T patent/PT2904092T/pt unknown
-
2015
- 2015-03-24 IL IL237916A patent/IL237916A0/en unknown
-
2017
- 2017-02-03 US US15/424,672 patent/US20170152540A1/en not_active Abandoned
- 2017-11-14 CY CY20171101192T patent/CY1119602T1/el unknown
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