JP2017508523A5 - - Google Patents
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- JP2017508523A5 JP2017508523A5 JP2016553431A JP2016553431A JP2017508523A5 JP 2017508523 A5 JP2017508523 A5 JP 2017508523A5 JP 2016553431 A JP2016553431 A JP 2016553431A JP 2016553431 A JP2016553431 A JP 2016553431A JP 2017508523 A5 JP2017508523 A5 JP 2017508523A5
- Authority
- JP
- Japan
- Prior art keywords
- culture
- fgf
- weeks
- compound
- days
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14000599 | 2014-02-20 | ||
| EP14000599.2 | 2014-02-20 | ||
| PCT/EP2015/053639 WO2015124735A1 (en) | 2014-02-20 | 2015-02-20 | Fgf-18 in graft transplantation and tissue engineering procedures |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017508523A JP2017508523A (ja) | 2017-03-30 |
| JP2017508523A5 true JP2017508523A5 (enExample) | 2018-02-22 |
| JP6495934B2 JP6495934B2 (ja) | 2019-04-03 |
Family
ID=50151087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553431A Active JP6495934B2 (ja) | 2014-02-20 | 2015-02-20 | グラフト移植および組織工学的手順におけるｆｇｆ−１８ |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20170056554A1 (enExample) |
| EP (1) | EP3107591B1 (enExample) |
| JP (1) | JP6495934B2 (enExample) |
| KR (1) | KR102437057B1 (enExample) |
| CN (1) | CN106232153B (enExample) |
| AR (1) | AR099557A1 (enExample) |
| AU (1) | AU2015220781B2 (enExample) |
| BR (1) | BR112016018704B1 (enExample) |
| ES (1) | ES2676318T3 (enExample) |
| IL (1) | IL247105B (enExample) |
| MX (1) | MX2016010873A (enExample) |
| RU (1) | RU2682159C2 (enExample) |
| SG (1) | SG11201606696UA (enExample) |
| WO (1) | WO2015124735A1 (enExample) |
| ZA (1) | ZA201605549B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20181573T1 (hr) | 2014-02-20 | 2018-11-30 | Merck Patent Gmbh | Implantat koji sadrži fgf-18 |
| JP6431083B2 (ja) | 2014-02-20 | 2018-11-28 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | Ｆｇｆ−１８化合物の投与計画 |
| CA2971315C (en) | 2015-01-29 | 2023-02-14 | Ares Trading S.A. | Immunoassays for high positively charged proteins |
| CN107058217A (zh) * | 2017-01-22 | 2017-08-18 | 广州赛莱拉干细胞科技股份有限公司 | 一种软骨细胞的增殖培养基及增殖培养方法 |
| AU2017404163A1 (en) * | 2017-03-17 | 2019-10-31 | The Trustees Of The University Of Pennsylvania | Cartilage preservation media |
| DK3687558T3 (da) | 2017-09-29 | 2022-06-20 | Merck Patent Gmbh | Metaboliske biomarkører til forudsigelse af modtageligheden på fgf-18 forbindelse |
| DK3688468T3 (da) | 2017-09-29 | 2022-06-20 | Merck Patent Gmbh | Inflammatoriske biomarkører til forudsigelse af modtageligheden for fgf-18 forbindelse |
| IL281333B2 (en) | 2018-09-10 | 2025-11-01 | Merck Patent Gmbh | A method for reducing risk in a clinical trial |
| CN113244413B (zh) * | 2021-06-28 | 2021-10-26 | 深圳市瑞吉生物科技有限公司 | 一种mRNA剂型的骨关节炎药物制剂及其制备方法和应用 |
| CN117230002A (zh) * | 2022-06-06 | 2023-12-15 | 友康生物科技(北京)股份有限公司 | 一种软骨细胞培养基 |
| IT202300012807A1 (it) * | 2023-06-26 | 2024-12-26 | Umberto Parri | Protesi d'anca in biomateriali e procedimento di fabbricazione |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511958B1 (en) * | 1997-08-14 | 2003-01-28 | Sulzer Biologics, Inc. | Compositions for regeneration and repair of cartilage lesions |
| US20140193468A1 (en) * | 2001-03-23 | 2014-07-10 | Histogenics Corporation | Methods for preparation of neo-cartilage constructs |
| US20040136970A1 (en) * | 2002-10-07 | 2004-07-15 | Ellsworth Jeff L. | Methods for administering FGF18 |
| MY148277A (en) * | 2006-08-25 | 2013-03-29 | Ares Trading Sa | Treatment of cartilage disorders with fgf-18 |
| KR101419961B1 (ko) * | 2006-08-25 | 2014-07-30 | 아레스 트레이딩 에스.에이. | Ｆｇｆ-18 로 연골 질환의 치료 |
| JP5388233B2 (ja) * | 2011-01-19 | 2014-01-15 | 富士ソフト株式会社 | 再生軟骨の軟骨特性を評価する方法 |
-
2015
- 2015-02-20 BR BR112016018704-0A patent/BR112016018704B1/pt active IP Right Grant
- 2015-02-20 CN CN201580020522.0A patent/CN106232153B/zh active Active
- 2015-02-20 ES ES15705823.1T patent/ES2676318T3/es active Active
- 2015-02-20 MX MX2016010873A patent/MX2016010873A/es active IP Right Grant
- 2015-02-20 EP EP15705823.1A patent/EP3107591B1/en active Active
- 2015-02-20 RU RU2016137290A patent/RU2682159C2/ru active
- 2015-02-20 AU AU2015220781A patent/AU2015220781B2/en active Active
- 2015-02-20 US US15/120,136 patent/US20170056554A1/en not_active Abandoned
- 2015-02-20 KR KR1020167025249A patent/KR102437057B1/ko active Active
- 2015-02-20 SG SG11201606696UA patent/SG11201606696UA/en unknown
- 2015-02-20 JP JP2016553431A patent/JP6495934B2/ja active Active
- 2015-02-20 WO PCT/EP2015/053639 patent/WO2015124735A1/en not_active Ceased
- 2015-02-20 AR ARP150100506A patent/AR099557A1/es active IP Right Grant
-
2016
- 2016-08-04 IL IL247105A patent/IL247105B/en active IP Right Grant
- 2016-08-10 ZA ZA2016/05549A patent/ZA201605549B/en unknown
-
2022
- 2022-06-16 US US17/842,762 patent/US20220378981A1/en active Pending
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