RS63292B1 - Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18 - Google Patents

Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18

Info

Publication number
RS63292B1
RS63292B1 RS20220541A RSP20220541A RS63292B1 RS 63292 B1 RS63292 B1 RS 63292B1 RS 20220541 A RS20220541 A RS 20220541A RS P20220541 A RSP20220541 A RS P20220541A RS 63292 B1 RS63292 B1 RS 63292B1
Authority
RS
Serbia
Prior art keywords
fgf
compound
predicting responsiveness
inflammatory biomarkers
biomarkers
Prior art date
Application number
RS20220541A
Other languages
English (en)
Inventor
Christoph H Ladel
Hans Guehring
Anne-Christine Bay-Jensen
Morten Karsdal
Per Qvist
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of RS63292B1 publication Critical patent/RS63292B1/sr

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
RS20220541A 2017-09-29 2018-09-28 Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18 RS63292B1 (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP17194169 2017-09-29
EP18169317 2018-04-25
PCT/EP2018/076391 WO2019063756A1 (en) 2017-09-29 2018-09-28 INFLAMMATORY BIOMARKERS FOR PREDICTING REACTIVITY TO FGF-18 COMPOUND
EP18782012.1A EP3688468B1 (en) 2017-09-29 2018-09-28 Inflammatory biomarkers for predicting responsiveness to fgf-18 compound

Publications (1)

Publication Number Publication Date
RS63292B1 true RS63292B1 (sr) 2022-06-30

Family

ID=63722379

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20220541A RS63292B1 (sr) 2017-09-29 2018-09-28 Inflamatorni biomarkeri za predviđanje responsivnosti na jedinjenje fgf-18

Country Status (16)

Country Link
US (2) US11467169B2 (sr)
EP (1) EP3688468B1 (sr)
JP (1) JP7418324B2 (sr)
CN (1) CN111164429A (sr)
AU (1) AU2018343980A1 (sr)
CA (1) CA3075713A1 (sr)
DK (1) DK3688468T3 (sr)
ES (1) ES2918249T3 (sr)
HR (1) HRP20220737T1 (sr)
HU (1) HUE058848T2 (sr)
IL (1) IL273574A (sr)
LT (1) LT3688468T (sr)
PL (1) PL3688468T3 (sr)
RS (1) RS63292B1 (sr)
SI (1) SI3688468T1 (sr)
WO (1) WO2019063756A1 (sr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT3687558T (lt) 2017-09-29 2022-06-27 Merck Patent Gmbh Metaboliniai biožymenys, skirti atsako į fgf-18 junginį numatymui

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9712348B1 (pt) 1996-10-16 2013-06-18 vetor de expressão, célula de bactéria ou levedura transformada ou transfectada, processo para produzir um polipeptídeo homólogo de fgf, composição farmacêutica, e, processos para estimular ex vivo células progenitoras de miócitos ou miócitos
US20040136970A1 (en) 2002-10-07 2004-07-15 Ellsworth Jeff L. Methods for administering FGF18
PT1828239E (pt) 2004-12-10 2011-10-27 Zymogenetics Inc Produção de fgf18 em hospedeiros procarióticos
JP5815206B2 (ja) 2006-08-25 2015-11-17 アレス トレーディング ソシエテ アノニム Fgf−18を用いた軟骨障害の治療
AU2013301606B2 (en) 2012-08-06 2018-08-02 Merck Patent Gmbh Genetic markers for predicting responsiveness to FGF-18 compound
WO2015084883A2 (en) * 2013-12-02 2015-06-11 Abbvie, Inc. Compositions and methods for treating osteoarthritis
SG11201606505UA (en) * 2014-02-20 2016-09-29 Merck Patent Gmbh Fgf-18 compound dosing regimen
LT3687558T (lt) 2017-09-29 2022-06-27 Merck Patent Gmbh Metaboliniai biožymenys, skirti atsako į fgf-18 junginį numatymui

Also Published As

Publication number Publication date
US20210231680A1 (en) 2021-07-29
SI3688468T1 (sl) 2022-08-31
JP7418324B2 (ja) 2024-01-19
PL3688468T3 (pl) 2022-07-18
HUE058848T2 (hu) 2022-09-28
DK3688468T3 (da) 2022-06-20
JP2020535423A (ja) 2020-12-03
EP3688468A1 (en) 2020-08-05
CA3075713A1 (en) 2019-04-04
US20230258659A1 (en) 2023-08-17
US11467169B2 (en) 2022-10-11
LT3688468T (lt) 2022-06-27
EP3688468B1 (en) 2022-03-16
HRP20220737T1 (hr) 2022-09-02
AU2018343980A1 (en) 2020-04-02
WO2019063756A1 (en) 2019-04-04
ES2918249T3 (es) 2022-07-14
CN111164429A (zh) 2020-05-15
IL273574A (en) 2020-05-31

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