JP2017508479A5 - - Google Patents
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- Publication number
- JP2017508479A5 JP2017508479A5 JP2016572917A JP2016572917A JP2017508479A5 JP 2017508479 A5 JP2017508479 A5 JP 2017508479A5 JP 2016572917 A JP2016572917 A JP 2016572917A JP 2016572917 A JP2016572917 A JP 2016572917A JP 2017508479 A5 JP2017508479 A5 JP 2017508479A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- ucb
- population
- hla
- pooled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 210000000822 natural killer cell Anatomy 0.000 claims 32
- 238000000034 method Methods 0.000 claims 17
- 210000004027 cell Anatomy 0.000 claims 13
- 230000000779 depleting effect Effects 0.000 claims 6
- 102100033627 Killer cell immunoglobulin-like receptor 3DL1 Human genes 0.000 claims 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 4
- 101000945371 Homo sapiens Killer cell immunoglobulin-like receptor 2DL2 Proteins 0.000 claims 4
- 102100033599 Killer cell immunoglobulin-like receptor 2DL2 Human genes 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 238000011176 pooling Methods 0.000 claims 4
- 230000002062 proliferating effect Effects 0.000 claims 4
- 101000945351 Homo sapiens Killer cell immunoglobulin-like receptor 3DL1 Proteins 0.000 claims 3
- 101000945490 Homo sapiens Killer cell immunoglobulin-like receptor 3DL2 Proteins 0.000 claims 3
- 108010043610 KIR Receptors Proteins 0.000 claims 3
- 102100034840 Killer cell immunoglobulin-like receptor 3DL2 Human genes 0.000 claims 3
- 230000003213 activating effect Effects 0.000 claims 3
- 230000002401 inhibitory effect Effects 0.000 claims 3
- 108010002634 HLA-Bw4 antigen Proteins 0.000 claims 2
- 101001027081 Homo sapiens Killer cell immunoglobulin-like receptor 2DL1 Proteins 0.000 claims 2
- 102100037363 Killer cell immunoglobulin-like receptor 2DL1 Human genes 0.000 claims 2
- 238000001994 activation Methods 0.000 claims 2
- 230000003321 amplification Effects 0.000 claims 2
- 210000003743 erythrocyte Anatomy 0.000 claims 2
- 230000008014 freezing Effects 0.000 claims 2
- 238000007710 freezing Methods 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 238000003199 nucleic acid amplification method Methods 0.000 claims 2
- 238000010257 thawing Methods 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 101000945333 Homo sapiens Killer cell immunoglobulin-like receptor 2DL3 Proteins 0.000 claims 1
- 102000002698 KIR Receptors Human genes 0.000 claims 1
- 102100033634 Killer cell immunoglobulin-like receptor 2DL3 Human genes 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 239000012190 activator Substances 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 230000001747 exhibiting effect Effects 0.000 claims 1
- 210000004700 fetal blood Anatomy 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14305332.0 | 2014-03-07 | ||
| EP14305332 | 2014-03-07 | ||
| PCT/EP2015/054837 WO2015132415A1 (en) | 2014-03-07 | 2015-03-09 | Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020071370A Division JP2020114248A (ja) | 2014-03-07 | 2020-04-10 | 臍帯血由来のプールｎｋ細胞並びにがん及び慢性感染症の治療のためのこれらの用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017508479A JP2017508479A (ja) | 2017-03-30 |
| JP2017508479A5 true JP2017508479A5 (enExample) | 2018-04-19 |
| JP6775426B2 JP6775426B2 (ja) | 2020-10-28 |
Family
ID=50277168
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016572917A Active JP6775426B2 (ja) | 2014-03-07 | 2015-03-09 | 臍帯血由来のプールｎｋ細胞並びにがん及び慢性感染症の治療のためのこれらの用途 |
| JP2020071370A Pending JP2020114248A (ja) | 2014-03-07 | 2020-04-10 | 臍帯血由来のプールｎｋ細胞並びにがん及び慢性感染症の治療のためのこれらの用途 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020071370A Pending JP2020114248A (ja) | 2014-03-07 | 2020-04-10 | 臍帯血由来のプールｎｋ細胞並びにがん及び慢性感染症の治療のためのこれらの用途 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20170073637A1 (enExample) |
| EP (1) | EP3114215B1 (enExample) |
| JP (2) | JP6775426B2 (enExample) |
| CN (1) | CN106164256B (enExample) |
| CA (1) | CA2941519C (enExample) |
| DK (1) | DK3114215T3 (enExample) |
| ES (1) | ES2880718T3 (enExample) |
| WO (1) | WO2015132415A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017042393A1 (en) * | 2015-09-11 | 2017-03-16 | Emercell Sas | Pooled nk cells from umbilical cord blood associated with antibodies and their uses for the treatment of disease |
| KR20180086204A (ko) * | 2015-11-05 | 2018-07-30 | 글리코스템 떼라퓨틱스 비.브이. | 면역치료법에 사용하기 위한 조성물 |
| EP3411414A4 (en) * | 2016-02-05 | 2019-10-23 | Washington University | COMPOSITIONS AND METHOD FOR TARGETED CYTOKINE RELIEF |
| EP3746095A4 (en) | 2018-02-01 | 2021-04-21 | Nkmax Co., Ltd. | Method of producing natural killer cells and composition for treating cancer |
| EP3755349A4 (en) | 2018-02-21 | 2021-11-17 | Board of Regents, The University of Texas System | PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES |
| DK3755347T3 (da) * | 2018-02-21 | 2025-08-04 | Univ Texas | Universelle antigenpræsenterende celler og anvendelser deraf |
| KR20210052494A (ko) | 2018-08-27 | 2021-05-10 | 아피메트 게엠베하 | 항체 구조물이 사전 로드된 동결 보존된 nk 세포 |
| WO2020152661A1 (ja) * | 2019-01-21 | 2020-07-30 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
| JP6838750B2 (ja) * | 2019-01-21 | 2021-03-03 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
| JP6977969B2 (ja) * | 2019-03-22 | 2021-12-08 | 株式会社ガイアバイオメディシン | 免疫細胞提供システム |
| JP2021035400A (ja) * | 2020-12-07 | 2021-03-04 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101077912B1 (ko) * | 2008-10-24 | 2011-10-31 | 주식회사 메디셀 | 제대혈로부터 효율적인 자연살해세포의 증식 및 분화 방법 |
| CA2703428A1 (en) * | 2010-05-11 | 2011-11-11 | Mcgill University Health Center | Pooled cord blood units |
| WO2012009422A1 (en) * | 2010-07-13 | 2012-01-19 | Anthrogenesis Corporation | Methods of generating natural killer cells |
| KR101447546B1 (ko) * | 2011-03-03 | 2014-10-08 | 한국생명공학연구원 | 제대혈 ｃｄ14 양성 단핵세포로부터 자연살해세포 분화 및 증식 방법 |
| WO2012146702A1 (en) * | 2011-04-28 | 2012-11-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preparing accessory cells and uses thereof for preparing activated nk cells |
| JP5840876B2 (ja) * | 2011-06-24 | 2016-01-06 | テラ株式会社 | Ｎｋ細胞を増幅するための組成物及び方法 |
| JP5572863B2 (ja) * | 2011-06-24 | 2014-08-20 | 国立大学法人九州大学 | Ｎｋ細胞の増幅方法 |
| WO2014123879A1 (en) * | 2013-02-05 | 2014-08-14 | Anthrogenesis Corporation | Natural killer cells from placenta |
-
2015
- 2015-03-09 WO PCT/EP2015/054837 patent/WO2015132415A1/en not_active Ceased
- 2015-03-09 US US15/123,660 patent/US20170073637A1/en active Pending
- 2015-03-09 CA CA2941519A patent/CA2941519C/en active Active
- 2015-03-09 DK DK15709149.7T patent/DK3114215T3/da active
- 2015-03-09 EP EP15709149.7A patent/EP3114215B1/en active Active
- 2015-03-09 ES ES15709149T patent/ES2880718T3/es active Active
- 2015-03-09 CN CN201580011900.9A patent/CN106164256B/zh active Active
- 2015-03-09 JP JP2016572917A patent/JP6775426B2/ja active Active
-
2020
- 2020-04-10 JP JP2020071370A patent/JP2020114248A/ja active Pending
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