CA2941519C - Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease - Google Patents
Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease Download PDFInfo
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- CA2941519C CA2941519C CA2941519A CA2941519A CA2941519C CA 2941519 C CA2941519 C CA 2941519C CA 2941519 A CA2941519 A CA 2941519A CA 2941519 A CA2941519 A CA 2941519A CA 2941519 C CA2941519 C CA 2941519C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
- A01N1/146—Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0081—Purging biological preparations of unwanted cells
- C12N5/0087—Purging against subsets of blood cells, e.g. purging alloreactive T cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0665—Blood-borne mesenchymal stem cells, e.g. from umbilical cord blood
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2315—Interleukin-15 (IL-15)
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
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- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Dentistry (AREA)
- Oncology (AREA)
- Environmental Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Virology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14305332.0 | 2014-03-07 | ||
| EP14305332 | 2014-03-07 | ||
| PCT/EP2015/054837 WO2015132415A1 (en) | 2014-03-07 | 2015-03-09 | Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2941519A1 CA2941519A1 (en) | 2015-09-11 |
| CA2941519C true CA2941519C (en) | 2022-09-06 |
Family
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Family Applications (1)
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| CA2941519A Active CA2941519C (en) | 2014-03-07 | 2015-03-09 | Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease |
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| WO2017042393A1 (en) * | 2015-09-11 | 2017-03-16 | Emercell Sas | Pooled nk cells from umbilical cord blood associated with antibodies and their uses for the treatment of disease |
| KR20180086204A (ko) * | 2015-11-05 | 2018-07-30 | 글리코스템 떼라퓨틱스 비.브이. | 면역치료법에 사용하기 위한 조성물 |
| EP3411414A4 (en) * | 2016-02-05 | 2019-10-23 | Washington University | COMPOSITIONS AND METHOD FOR TARGETED CYTOKINE RELIEF |
| EP3746095A4 (en) | 2018-02-01 | 2021-04-21 | Nkmax Co., Ltd. | Method of producing natural killer cells and composition for treating cancer |
| EP3755349A4 (en) | 2018-02-21 | 2021-11-17 | Board of Regents, The University of Texas System | PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES |
| DK3755347T3 (da) * | 2018-02-21 | 2025-08-04 | Univ Texas | Universelle antigenpræsenterende celler og anvendelser deraf |
| KR20210052494A (ko) | 2018-08-27 | 2021-05-10 | 아피메트 게엠베하 | 항체 구조물이 사전 로드된 동결 보존된 nk 세포 |
| WO2020152661A1 (ja) * | 2019-01-21 | 2020-07-30 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
| JP6838750B2 (ja) * | 2019-01-21 | 2021-03-03 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
| JP6977969B2 (ja) * | 2019-03-22 | 2021-12-08 | 株式会社ガイアバイオメディシン | 免疫細胞提供システム |
| JP2021035400A (ja) * | 2020-12-07 | 2021-03-04 | 株式会社ガイアバイオメディシン | Ｎｋ細胞を含む細胞集団の製造方法 |
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| KR101077912B1 (ko) * | 2008-10-24 | 2011-10-31 | 주식회사 메디셀 | 제대혈로부터 효율적인 자연살해세포의 증식 및 분화 방법 |
| CA2703428A1 (en) * | 2010-05-11 | 2011-11-11 | Mcgill University Health Center | Pooled cord blood units |
| WO2012009422A1 (en) * | 2010-07-13 | 2012-01-19 | Anthrogenesis Corporation | Methods of generating natural killer cells |
| KR101447546B1 (ko) * | 2011-03-03 | 2014-10-08 | 한국생명공학연구원 | 제대혈 ｃｄ14 양성 단핵세포로부터 자연살해세포 분화 및 증식 방법 |
| WO2012146702A1 (en) * | 2011-04-28 | 2012-11-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preparing accessory cells and uses thereof for preparing activated nk cells |
| JP5840876B2 (ja) * | 2011-06-24 | 2016-01-06 | テラ株式会社 | Ｎｋ細胞を増幅するための組成物及び方法 |
| JP5572863B2 (ja) * | 2011-06-24 | 2014-08-20 | 国立大学法人九州大学 | Ｎｋ細胞の増幅方法 |
| WO2014123879A1 (en) * | 2013-02-05 | 2014-08-14 | Anthrogenesis Corporation | Natural killer cells from placenta |
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| ES2880718T3 (es) | 2021-11-25 |
| DK3114215T3 (da) | 2021-06-21 |
| JP2017508479A (ja) | 2017-03-30 |
| US20170073637A1 (en) | 2017-03-16 |
| WO2015132415A1 (en) | 2015-09-11 |
| CN106164256A (zh) | 2016-11-23 |
| EP3114215A1 (en) | 2017-01-11 |
| JP6775426B2 (ja) | 2020-10-28 |
| JP2020114248A (ja) | 2020-07-30 |
| CN106164256B (zh) | 2021-08-10 |
| CA2941519A1 (en) | 2015-09-11 |
| EP3114215B1 (en) | 2021-04-14 |
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