JP2016500260A5 - - Google Patents
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- Publication number
- JP2016500260A5 JP2016500260A5 JP2015547149A JP2015547149A JP2016500260A5 JP 2016500260 A5 JP2016500260 A5 JP 2016500260A5 JP 2015547149 A JP2015547149 A JP 2015547149A JP 2015547149 A JP2015547149 A JP 2015547149A JP 2016500260 A5 JP2016500260 A5 JP 2016500260A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cells
- gene
- tet3
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 29
- 238000000034 method Methods 0.000 claims 19
- 101150070537 Tet3 gene Proteins 0.000 claims 7
- 230000004069 differentiation Effects 0.000 claims 7
- 239000012634 fragment Substances 0.000 claims 7
- 210000001082 somatic cell Anatomy 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 101000653369 Homo sapiens Methylcytosine dioxygenase TET3 Proteins 0.000 claims 2
- 102100030812 Methylcytosine dioxygenase TET3 Human genes 0.000 claims 2
- 108010029485 Protein Isoforms Proteins 0.000 claims 2
- 102000001708 Protein Isoforms Human genes 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 101150033839 4 gene Proteins 0.000 claims 1
- 101100510267 Mus musculus Klf4 gene Proteins 0.000 claims 1
- 101710135898 Myc proto-oncogene protein Proteins 0.000 claims 1
- 101150086694 SLC22A3 gene Proteins 0.000 claims 1
- 101150037203 Sox2 gene Proteins 0.000 claims 1
- 101710150448 Transcriptional regulator Myc Proteins 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 238000000684 flow cytometry Methods 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1222693.2A GB201222693D0 (en) | 2012-12-17 | 2012-12-17 | Novel method |
| GB1222693.2 | 2012-12-17 | ||
| PCT/GB2013/053317 WO2014096800A1 (en) | 2012-12-17 | 2013-12-17 | Novel method |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018218938A Division JP2019058176A (ja) | 2012-12-17 | 2018-11-22 | 新規方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500260A JP2016500260A (ja) | 2016-01-12 |
| JP2016500260A5 true JP2016500260A5 (enExample) | 2017-02-02 |
Family
ID=47630838
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015547149A Pending JP2016500260A (ja) | 2012-12-17 | 2013-12-17 | 新規方法 |
| JP2018218938A Pending JP2019058176A (ja) | 2012-12-17 | 2018-11-22 | 新規方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018218938A Pending JP2019058176A (ja) | 2012-12-17 | 2018-11-22 | 新規方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20160186207A1 (enExample) |
| EP (1) | EP2931881A1 (enExample) |
| JP (2) | JP2016500260A (enExample) |
| CN (1) | CN105051188A (enExample) |
| AU (1) | AU2013366092A1 (enExample) |
| CA (1) | CA2894822A1 (enExample) |
| GB (1) | GB201222693D0 (enExample) |
| WO (1) | WO2014096800A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010037001A2 (en) | 2008-09-26 | 2010-04-01 | Immune Disease Institute, Inc. | Selective oxidation of 5-methylcytosine by tet-family proteins |
| CN107254539A (zh) | 2011-07-29 | 2017-10-17 | 剑桥表现遗传学有限公司 | 用于检测核苷酸修饰的方法 |
| ES2786984T3 (es) | 2012-11-30 | 2020-10-14 | Cambridge Epigenetix Ltd | Agente oxidante para nucleótidos modificados |
| GB201403216D0 (en) | 2014-02-24 | 2014-04-09 | Cambridge Epigenetix Ltd | Nucleic acid sample preparation |
| CN104630272A (zh) * | 2015-01-06 | 2015-05-20 | 西北农林科技大学 | 一种基于去甲基化促进生殖干细胞自我更新和增殖的载体及其应用 |
| CA3006432A1 (en) | 2015-12-04 | 2017-06-08 | Novartis Ag | Compositions and methods for immunooncology |
| WO2018073787A2 (en) * | 2016-10-19 | 2018-04-26 | Fred Hutchinson Cancer Research Center | Compositions and methods for reprogramming cells and for somatic cell nuclear transfer using duxc expression |
| SG11201907434RA (en) * | 2017-03-22 | 2019-10-30 | Novartis Ag | Compositions and methods for immunooncology |
| WO2018222139A1 (en) | 2017-05-29 | 2018-12-06 | Agency For Science, Technology And Research | Markers of totipotency and methods of use |
| WO2019164876A1 (en) * | 2018-02-20 | 2019-08-29 | The Regents Of The University Of California | Therapeutics that invoke epigenetic changes for use in treating neurological conditions such as cognitive impairment |
| WO2020028617A1 (en) | 2018-08-01 | 2020-02-06 | University Of Georgia Research Foundation, Inc. | Compositions and methods for improving embryo development |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101420740B1 (ko) * | 2005-12-13 | 2014-07-17 | 교또 다이가꾸 | 핵초기화 인자 |
| WO2010037001A2 (en) * | 2008-09-26 | 2010-04-01 | Immune Disease Institute, Inc. | Selective oxidation of 5-methylcytosine by tet-family proteins |
-
2012
- 2012-12-17 GB GBGB1222693.2A patent/GB201222693D0/en not_active Ceased
-
2013
- 2013-12-17 EP EP13808199.7A patent/EP2931881A1/en not_active Withdrawn
- 2013-12-17 WO PCT/GB2013/053317 patent/WO2014096800A1/en not_active Ceased
- 2013-12-17 CN CN201380070275.6A patent/CN105051188A/zh active Pending
- 2013-12-17 CA CA2894822A patent/CA2894822A1/en not_active Abandoned
- 2013-12-17 US US14/652,742 patent/US20160186207A1/en not_active Abandoned
- 2013-12-17 AU AU2013366092A patent/AU2013366092A1/en not_active Abandoned
- 2013-12-17 JP JP2015547149A patent/JP2016500260A/ja active Pending
-
2018
- 2018-11-22 JP JP2018218938A patent/JP2019058176A/ja active Pending
- 2018-12-21 US US16/231,206 patent/US20190264223A1/en not_active Abandoned
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